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Maturation of Erythrocytes
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HEMATOPOIESIS Subdivisions
stem
cell
Myelopoiesis
PMN
Bas
Lym
Mon
Eos
Pla
RBC
Lymphopoiesis
Granulopoiesis
Monocytopoiesis
Erythropoiesis
Megakaryopoiesis
Thrombopoiesis
{
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Erythropoiesis:
is the formation of red blood cells, i.e., the
developmental processes of the red blood cells.
occurs in the red bone marrow from the
descendants of the proerythroblast stem cell by the
processes of proliferation and differentiation
each hemocytoblast stem cell can give rise to as
many as 211 mature cells.
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Proerythroblast is:
also called a pronormoblast
the earliest stem cell (derived from the hemocytoblast = pluripotent hemopoietic cell)
found in the red bone marrow which is committed to develop into a red blood cell.
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The retculocyte is characterized by a bluish hue due to ribosomes remaining in its cytoplasm.
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Reticulocyte Red Blood Cell
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Polychromotatophilic Normoblasat Orthochromatophilic Normoblast and Reticulocyte
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Hemopoietic Growth Factor is:
any of the various regulatory proteins and
local hormones which:
▪ target the hematopoietic stem cells in the red
bone marrow
▪ promote the growth, organization, and
maintenance of red bone marrow and blood cells.
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Erythropoietin is:
also referred to as EPO.
a glycoprotein hormone which stimulates the
production of red blood cells by stem cells in the
red bone marrow.
produced mainly by the kidneys.
released in response to decreased levels of oxygen
detected in the blood in the kidney nephron.
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