Mahasen Ali Radwan, Ph.D. Professor of Clinical Pharmacy
Department of Pharmaceutics and Pharmaceutical Technology
College of Pharmacy
Egyptian Russian University
Suez road, Bader City, Cairo, 11829, Egypt
Tel: +20-2-22636589 / Mobile: +20-1005211461
NATIONALITY: Egyptian
SEX: Female
MARITAL STATUS: Married
EMAIL: [email protected] [email protected]
DATE: January 2019
EDUCATION
March 1988 Ph.D. - College of Pharmacy, University of Georgia, GA, U.S.A.
Dissertation - "Microencapsulation of Disopyramide for Oral Sustained
Release and Subsequent Pharmacokinetic Studies in the Dog"
Major Professors - Drs. James C. Price and Randall L. Tackett.
August 1985 M.Sc. - College of Pharmacy, University of Georgia, GA, U.S.A.
Thesis - "Development of an HPLC Assay for Quantitation of
Oxamniquine in Biological Samples and its Application to
Pharmacokinetic and Tissue Distribution Studies in Animals"
Major Professor- H Won Jun.
May 1978 B.Sc. with honor, College of Pharmacy, Cairo University, Cairo, Egypt.
WORK EXPERIENCE
December 2017 – Present
Head of the department of Pharmaceutics and Pharmaceutical Technology,
Head of the fifth year's Control, College of Pharmacy, Egyptian Russian
University (ERU), Bader City, Cairo, Egypt
September 2016 – Present
Professor-College of Pharmacy, Department of Pharmaceutics and
Pharmaceutical Technology, ERU, Bader City, Cairo, Egypt
Teaching responsibilities at ERU: Teaching undergraduate courses: Pharmacy
Practice I, Pharmacy Practice II, Clinical Pharmacy I, Clinical Pharmacy II,
Hospital Pharmacy and Biopharmaceutics and Pharmacokinetics.
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September 2011 – August 2016
Professor-College of Pharmacy, Department of Pharmaceutical Practice,
Princess Nourah bint Abdulrahahman University (PNU) Riyadh, Saudi Arabia.
Teaching responsibilities at PNU: Teaching and sharing teaching undergraduate
courses, CPP312 (Biopharmaceutics and Pharmacokinetics) to level 5 or 6,
CPP411 (Drug information and Literature Evaluation) to level 7 and CPP416
(Principles of Evidence Based Practice) to level 8.
2013- 2016: Scientific Coordinator-Foundation Year – PNU Health
Colleges. 2011-2013: Supervisor of the Academic Advisory and Student
Support Unit.
2011-2016: Internal Supervisor for Bushra AlQuadeib, Ph.D. through the
External supervision program of King Saud University with Newcastle
University,
Newcastle, United Kingdom. Thesis title: “Pharmaceutical Studies of
Amphotericin – B: Oral Formulation using Nanotechnology”
2013-2018: Internal Supervisor for Alanoud Almurshidy through the
External supervision program of King Saud University with Liverpool
University, Liverpool, United Kingdom. Thesis title: “Development of Afatinib
lipid nanoparticles targeting Non-Small Cell Lung Cancer”
June 2002 – August 2011
Professor-College of Pharmacy, Department of Clinical Pharmacy, King Saud
University (KSU) Riyadh, Saudi Arabia.
December 1995 – June 2002
Associate Professor-College of Pharmacy, Department of Clinical Pharmacy,
King Saud University, Riyadh, Saudi Arabia.
September 1992 – December 1995
Assistant Professor-College of Pharmacy, Department of Clinical Pharmacy,
King Saud University, Riyadh, Saudi Arabia.
Teaching responsibilities at KSU- Sharing teaching of undergraduate and
graduate courses, Departments of Clinical Pharmacy (PHCL) and
Pharmaceutics (PHT) as: PHCL481 (Evidence Based Medicine), PHCL 311
(Pharmacy Practice), PHCL461 (Basic Pharmacokinetics), PHCL462 (Clinical
Pharmacokinetics), PHCL510 (Graduate-Advanced Clinical Pharmacokinetics),
PHT531(Graduate-Advanced Biopharmaceutics), PHT533(Graduate-Controlled
Drug Delivery Systems), PHT 521 (Graduate Hospital Pharmacy),
PHT451(Dispensing of Medication I), PHCL476 (Computer in Pharmacy),
PHCL471(Hospital Pharmacy) and PHT351 (Sterile Products).
Supervisor for M.Sc. Students: Ola Alomran, Maha Alderimli, Nouf Alouda,
Rania Algezani, Safaa Almyibid, Esraa Altaweel, Leena Said; in their research
projects (Department of Clinical Pharmacy).
Co Supervisor for M.Sc. Students: Zahra Alrays, Department of Zoology,
Yossra Alzeen, Department of Biochemistry, College of Science.
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Co Supervisor for Ph.D. Students Rash Kamel Department of Biotechnical
Engineer (Syria).
External Examiner: M.Sc Students (Department of Pharmaceutics and
Zoology).
April 1989 - August 1992
Assistant Professor - Albany College of Pharmacy, Department of
Pharmaceutics, Albany, NY, U.S.A.
Responsibilities: Shared teaching duties in required and elective pharmacy
courses in pharmaceutics, Course Coordinator of Biopharmaceutics and
Pharmacokinetics, and taught Clinical Pharmacokinetics course to
Pharm.D students. Conducted research in the area of Pharmacokinetics,
Pharmaceutical Drug Delivery Systems and Drug Analysis.
Supervised Pharm.D. and undergraduate students in different research
projects.
March 1988 - March 1989
Research Associate, Pharmaceutical Research and Development,
Hoffmann-La Roche, Nutley, NJ, U.S.A.
Responsibilities included the development of In Vitro release techniques to study
the effect of excipients on drug release to screen different formulations,
correlation between in vitro and in vivo results, development of parenteral
sustained release formulations and studying the effect of formulations on drug
disposition and bioavailability in rats.
April 1985 - February 1988
Teaching Assistant - Department of Pharmaceutics, College of Pharmacy,
University of Georgia, U.S.A.
Responsible for assisting junior students in dispensing laboratories
August 1983 - June 1984
November 1978 - June 1984
Inspector - Ministry of Health, Cairo, Egypt
Responsible for inspecting the activities of the scientific offices according to
Ministry of Health regulations and the registration of new drugs in Egypt
according to Ministry of Health and FDA guidelines.
DISTIGUISHED RESEARCH AND PUBLICATION QUALITY AWARDS:
From PNU (2016):
1. Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc, Ben Horrock, Matthew Wright
“Stealth Amphotericin B Nanoparticles For Oral Drug Delivery: In Vitro Optimization” Saudi
Pharmaceutical Journal, 23 (3):290-302 (2015) ISI*
2. Mahasen A. Radwan, Amal El Sayeh F. Abou el Ela, Maha A. Hassan and Dalia A. El-
Maraghy “Pharmacokinetics and Analgesic Effect and of Ketorolac Floating Delivery System”
Drug Delivery , 22(3): 320–327 (2015) ISI*
3. Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc, Elaine Mutch, Ben Horrock,
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Matthew Wright and Abdulaziz Alshaer “Therapeutic Monitoring of Amphotericin B in Saudi
ICU Patients using UPLC MS/MS Assay” Biomedical Chromatography, 28 (12): 1652–1659,
(2014) ISI*
4. Mahasen A. Radwan, Nayira A. Abdel Baky, Iman Y. Zaghloul , Hassan Y. Aboul‐Enein,
“Pharmacokinetics and Cardiovascular Effect of Etoricoxib in the Absence or Presence of
St. John's Wort in Rats” ArzneimittelForschun-Drug Research, 62: 313–318 (2012). ISI*
From KSU (2011 & 2015):
1. Mahasen A. Radwan, Amal El Sayeh F. Abou el Ela, Maha A. Hassan and Dalia A. El-
Maraghy “Pharmacokinetics and Analgesic Effect and of Ketorolac Floating Delivery System”
Drug Delivery , 22(3): 320–327 (2015). ISI*
2. Mahasen A. Radwan, , Bushra T. Alquadeib, Nouf M. Aloudah, Hassan Y. Aboul
Enein“Pharmacokinetics of Ketorolac Loaded to Polyethylcyanoacrylate Nanoparticles
Using UPLC MS/MS for its Determination in Rats” International Journal of Pharmaceutics
Volume 397(1-2):173-178(2010) ISI
3. Zaghloul IY, Radwan MA, Al Jaser MH, Al Issa R “Clinical Efficacy and
Pharmacokinetics of Antimony in Cutaneous Leishmaniasis Patients Treated With Sodium
Stibogluconate” : Journal of Clinical Pharmacology, 50(11):1230-1237 (2010).
4. Mahasen A. Radwan, Iman Y. Zaghloul, Nayira A. Abdel Baky “Stability indicating high
performance liquid chromatographic assay for the pharmacokinetics of Cyclooxygenase
(COX-2) inhibitor etoricoxib in rats” African J. of Pharmacy & Pharmacology, 3(7):339346
(2009). ISI
RESEARCH INTERESTS
Development and Pharmacokinetics of drug delivery systems especially
Nanoparticles and drug targeting, Clinical Pharmacokinetics (Therapeutic Drug
Monitoring and Drug interaction) and Pharmacogenomics. Drug Analysis in
biological fluids using HPLC, UPLC MS/MS, and Chiral analysis. The effect of
Diatery Supplements, especially antioxidents, on the pharmacokinetics of drugs.
Computer data handling and modeling using in-house or commercial software.
VISITING SCIENTIST
July-September 2008 School of Pharmacy and Pharmaceutical Science, University of Central
Lancashire, Preston,UK. To conduct research in the area of liposomes and
niosomes (Nanoparticles) for amphotericin B oral and lung delivery with
Professor Anthony D'Emanuelle.
July-August 2004
Department of Pharmaceutical Technology, Free University of Berlin, Berlin,
Germany. To conduct research in the area of Solid Lipid Nanoparticles (SLN)
of amphotericin B and Cyclosporin with Professor Rainer Mueller.
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COMMITTEES AND SCIENTIFIC SERVICE (Some)
November 2016 – Present: The head of the “Community participation and environmental
development”committee.
November 2015 - July 2016: Consultant to AlFisal New College of Pharmacy to Build the
Course Specifications, Laboratory and Program According to the NCAAA
Requirement.
September 2015 - August 2016: A member of the College of Pharmacy Research Center.
August 2014 - June 2015: A member of the “Standing Committee of Scientific Publications
Subdivision of the Scientific Council, Princess Nourah bint Abdulrahman
University.
August 2011 - June 2015: A member of the Scientific Council, Princess Nourah bint Abdulrahman
University.
August 2011- June 2014: The head of “Standing Committee of Employment and Scientific
Awards” Subdivision of the Scientific Council, Princess Nourah bint
Abdulrahman University.
August 2013-June 2015: A member of the “Standing Committee for Research Excellence” for the
awards of the distingushed research and distingushed researchers at Princess
Nourah bint Abdulrahman University.
2013 –2016: The head of the “Scientific Research Committee and Community Service” for the
quality assurance and Academic Accreditation of Standard 10 and 11 (Scientific
Research and Community Service).
2013-June 2015: A member of the “Princess Nourah research Center: Woman health research” for
the Princess Nourah Research Center and Central Labs: “Woman health
research”.
2013: A member of the “Commission to Study the scientific research and community service” for
studying the status of scientific research and community service at Princess
Nourah bint Abdulrahman University (Subdivision of the study of the Strategic
Plan of Princess Nourah bint Abdulrahman University for the future).
2013-June 2015: The head of the “Scientific Research Committee” for establishment of central
research laboratory of the College of Pharmacy of Princess Nourah bint
Abdulrahman University.
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2009-2011:
A member of the “Scientific Research Committee” for the establishment of the
construction and the selection of the design and equipment of the new Prince Naif
Central Research laboratory at King Saud University, new campus for girls.
2009-2011:
A member of the “Scientific Research Committee” for the establishment of the
College of Pharmacy Central Research laboratory at King Saud University new
campus for girls.
2010:
A member of the team of the “SWAT analysis” as part of the strategic plan of
King Saud University.
1995-2008:
A member of the Advisory Board of Saudi Pharmaceutical Journal.
1991-1992: A member of the “Task Force committee” for moving the curriculum of Albany
College of Pharmacy towards “All PharmD.” program, Albany, U.S.A.
1992-Present: A reviewer for the Journal of Pharmaceutical Sciences, European Journal of
Pharmaceutical Sciences, Pharmacy and Pharmacology, American Journal of
Health-System Pharmacy and others.
2000-Present: Referee for King Abdel Aziz for Science and Technology, for research proposal,
progress and finals reports.
ORGANIZATIONS
1. 1986-Present: Member of the American Association of Pharmaceutical Scientists
(AAPS).
2. 1994-Present: Member of the Saudi Pharmaceutical Association (SPHA). 3.
1987-Present: Controlled Release Society (CRS)
SELECTED TRAINING COURCES/WORKSHOPS ATTENDED
April 5 & 12 ,2016 “Professional Development” program, 12 hours, Center for Excellence in
Teaching and Learning. Pricess Nourah bint Abdulrahman University.
Feb. 25, 2016
“Professional Portfolio” program, 4 hours, Center for Excellence in Teaching
and Learning. Pricess Nourah bint Abdulrahman University.
Dec 29,2014
“Applying Standards of Quality Assurance and Academic Accreditation” Dr.
Hannan Algadhi, Pricess Nourah bint Abdulrahman University.
Dec 7, 2011 “Quality Assurance and Academic Accreditation” Dr. H. AlOlyan, Pricess
Nourah bint Abdulrahman University.
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Nov 30-Dec 2, 2010 “Teaching how to teach” Partners Harvard Medical International (Faculty
development Program) Novotel Hotel, Riyadh
Sept 19-21, 2010
“Motivating student, active learning and assessing student learning
Worhshop” by Experts from USA given in Almalaz Campus (Faculty
development Program), Riyadh
Feb 2-4, 2009
“Parametric and Nonparametric SPSS” training course, in Alisha Campus,
Riyadh.
Dec 2-3, 2008 “Reviewing and improving your teaching” (Faculty development
Program), Riyadh
Nov10-13, 2008 “TQD (UPLC-MS/MS) Operation and Maintenance course”, Waters
education Headquarter, Manchester, England.
PUBLICATIONS (Peer reviewed)
1. Alanood S. Almurshedi, Mahasen Radwan, Samia Omar, Ayodele A. Alaiya, Mohamed
M. Badran, Hanaa Elsaghire, Imran Y. Saleem, Gillian A. Hutcheon “A novel pH-sensitive
liposome to trigger delivery of afatinib to cancer cells: Impact on lung cancer therapy” J.
Molecular Liquids 259: 154–166 (2018) ISI*
2. Mahasen A. Radwan, Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc,
Matthew Wright Ben Horrock “Oral administration of amphotericin B nanoparticles:
antifungal activity, bioavailability and toxicity in rats” Drug Deliv, 24 (1):40-50 (2017)
ISI*
3. Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc, Ben Horrock, Matthew Wright
“Stealth Amphotericin B Nanoparticles For Oral Drug Delivery: In Vitro Optimization”
Saudi Pharmaceutical Journal, 23 (3):290-302 (2015) ISI*
4. Mahasen A. Radwan, Amal El Sayeh F. Abou el Ela, Maha A. Hassan and Dalia A. El-
Maraghy “Pharmacokinetics and Analgesic Effect and of Ketorolac Floating Delivery
System” Drug Delivery , 22(3): 320–327 (2015) ISI*
5. Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc, Elaine Mutch, Ben Horrock,
Matthew Wright and Abdulaziz Alshaer “Therapeutic Monitoring of Amphotericin B in
Saudi ICU Patients using UPLC MS/MS Assay” Biomedical Chromatography, 28 (12):
1652–1659, (2014) ISI*
6. Mahasen A. Radwan, Nayira A. Abdel Baky, Iman Y. Zaghloul , Hassan Y. Aboul‐Enein,
“Pharmacokinetics and Cardiovascular Effect of Etoricoxib in the Absence or Presence of
St. John's Wort in Rats” ArzneimittelForschun-Drug Research, 62: 313–318 (2012). ISI*
8
7. Mahasen A. Radwan, Esraa S. Al Taweel, Abdulrahman M. Al-Moghairi, Nouf M.
Aloudah, Muneera A. Al Babtain, Hussein S. Al-Amri “Metformin Monitoring in Cardiac
Patients exposed to Contrast Media using UHPLC MS/MS” Therapeutic Drug monitoring,
33:742–749 (2011). ISI*
8. Mahasen A. Radwan, Ghada A. Bawazeer, Nouf M. Aloudah, Bushra T. AlQuadeib,
Hassan Y. Aboul Enein “Determination of Free and Total Warfarin Concentrations in
Plasma Using UPLC MS/MS Assay: Application to Patient Samples” Biomedical
Chromatography, 26: 6–11 (2011). ISI
9. Mahasen A. Radwan, , Bushra T. Alquadeib, Nouf M. Aloudah, Hassan Y. Aboul-Enein
“Pharmacokinetics of Ketorolac Loaded to Polyethylcyanoacrylate Nanoparticles Using
UPLC MS/MS for its Determination in Rats” International Journal of Pharmaceutics
Volume 397(1-2):173-178(2010). ISI
10. Iman Y. Zaghloul, Mahasen A. Radwan, May H. Al Jaser and Ramadan Al Issa “Clinical
Efficacy and Pharmacokinetics of Antimony in Cutaneous Leishmaniasis Patients Treated
With Sodium Stibogluconate”, Journal of Clinical Pharmacology, November
,50(11):12301237(2010). ISI
11. Mahasen A. Radwan, Iman Y. Zaghloul, Nayira A. Abdel Baky “Stability indicating high
performance liquid chromatographic assay for the pharmacokinetics of Cyclooxygenase
(COX-2) inhibitor etoricoxib in rats” African J. of Pharmacy & Pharmacology,
3(7):339346 (2009). ISI
12. Nayira A. Abdel Baky, Nouf M. Al-Rasheed, Nawal M. Al-Rasheed, Iman Y Zaghloul,
and Mahasen A. Radwan “Alpha-lipoic acid and amlodipine ameliorate myocardial
infarction induced by isoproterenol in rats” International Journal of Academic Research, 1
(1): 68-77 (2009).
13. Mahasen A. Radwan, May H. AL Jaser, Zahra R. Al Rayes" The effects of induced
diabetes and cutaneous Leishmania infection on the pharmacokinetics of antimony in
hamsters" Annals of Tropical Medicine & Parasitology, 101 (1):1– 10 (2007). ISI
14. Iman Y. Zaghloul, Mahasen A. Radwan, Zinat H. Aly "The Effect of Chronic Cadmium
Exposure on the Pharmacokinetics of Theophylline and Ciprofloxacin in Rats" J. Trace
Elements in Medicine and Biology, 21:132-137 (2007). ISI
15. May H. AL Jaser, Mahasen A. Radwan, Iman Y. Zaghloul "Pharmacokinetics and tissue
distribution of antimony(v) after multiple intramuscular administrations in the hamster"
Saudi Pharmaceutical Journal, 14: 52-58 (2006). ISI
16. Nahla S. Barakat and Mahasen A. Radwan "In Vitro performance of carbamazepine
loaded to various molecular weights of poly (D, L - lactide - co - glycolide)"; Journal of
Drug Delivery, 13(1):9-18 (2006). ISI
17. Mahasen A. Radwan, Heba H. Abdine, Bushra T. Al-Quadeb, Hassan Y. Aboul-Enein
Kenichiro Nakashima “Steroselective HPLC assay of donepezil enantiomers with UV
detection and its application to Pharmacokinetics in rats” J. Chromatography B,
830:114119 (2006). ISI
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18. Mahasen A. Radwan, Heba H. Abdine, Hassan Y. Aboul-Enein “A Validated Chiral
HPLC Method for the Determination of Mebeverine HCl Enantiomers in Pharmaceutical
Dosage Forms and Spiked Rat Plasma” Biomedical Chromatography, 20(2):211-216
(2005). ISI
19. Norah O. Abanmy, Msc., Iman Y. Zaghloul, Ph.D., Mahasen A. Radwan, Ph.D.
"Compatibility of tramadol parentral injection with selected drugs and solutions";
American Journal of Health System Pharmacy, 62:1299-1302 (2005). ISI
20. Nouf M. Aloudah, Mahasen A. Radwan, Nasser F. Al Omar and Sydney Jacobs "HPLC
Assay of Fluconazole and its Application to Patients with Early Septic Shock"; J. of Liquid
Chromatography & related Technologies, 28: 591–600 (2005). ISI
21. Hassan Y. Aboul-Enein, Rajaa F. Hussein, Mahasen A. Radwan, Sameer Al-Rawithi
“Biotin dissolution from pharmaceutical dosage forms using an automated hplc system” J.
of Liquid Chromatography & related Technologies, 27:511-519 (2004). ISI
22. Mahasen A. Radwan and Hassan Abu El-Enein, “In Vitro Release and Stereoselective
Disposition of Flurbiprofen Loaded to Poly(D,L-Lactide-Co-glycolide) Nanoparticles in
Rats”. Chirality, 16:119-125 (2004). ISI
23. Al-Jaser, MH, El-Khameesy, SU, Ghannam, MM, Al-Essa, N, Al-Saleh, FM, Al-Garawi,
M, Zaghloul, I, Radwan M, Al Mubbarak, H, Al-Zuhai, H, Al-Garawi, M and AL-Ayed,
M, “Radioactivity Concentration in Surface Soil Samples from Al-Mezahmiah Area,
Southwest of Riyadh, Kingdom of Saudi Arabia”. Egyptian J. Biophysics, 36:4, 727733
(2004).
24. Al-Jaser, MH, El-Khameesy, SU, Ghannam, MM, Al-Saleh, FM, Al-Garawi, M, Zaghloul,
I, Radwan M, Al-Garawi, M, and AL-Ayed, M, “Radioactivity of 226Ra and 40K in the
ground water around Burraydah treatment plant in the northwest of Riyadh, Saudi Arabia”.
Egyptian J. Biophysics, (2003).
25. Magda A. El-Sherbeny, Huda S. Al-Salem, Maha A. Sultan, Mahasen A. Radwan, Hassan
Farag, and Hussein I. El-Subbagh, “Synthesis, in Vitro and in Vivo Evaluation of a Delivery
System for Targeting Anticancer Drugs to the Brain” Pharmazeutische und Medizinische
Chemie, 336:445-455 (2003). ISI
26. Hassan Abu El-Enein, Rajaa F. Hussein, Mahasen A. Radwan, Ahmad Yusuf, Wijdan
AL-Ahmadi, and Sameer Al-Rawithi ”Tamsulosin dissolution from pharmaceutical dosage
forms using an automated hplc system” J. of Liquid Chromatography & related
Technologies, 26:1109-1116 (2003). ISI
27. Mahasen A. Radwan, May H. AL Jaser, Iman Y. Zaghloul, and Shaheen M. Nakeeb
"Pharmacokinetics of Zidovudine and Pentavalent Antimony After Single and Steady State
Administrations In Leishmania Infected Hamsters" Saudi Pharmaceutical Journal, 10:
113-118 (2002). ISI
28. Mahasen A. Radwan and Hassan Y. Aboul-Enein “The effect of various oral absorption
enhancers on the in vivo performance of insulin–loaded poly(ethylcyanoacrylate)
nanospheres in diabetic rats” Journal of microencapsulation, 19:225-235 (2002). ISI
10
29. Mahasen A. Radwan “Enhancement of insulin – loaded polyisobutylcyanoacrylate
nanospheres absorption by sodium cholate after oral and subcutaneous administrations in
diabetic rats Drug Development and Industrial Pharmacy, 27:981-989 (2001). ISI
30. Mahasen A. Radwan and Hassan Y. Aboul-Enein “The effect of absorption enhancers on
the initial degradation kinetics of insulin by -chymotrypsin” International Journal of
Pharmaceutics, 217:111-120 (2001). ISI
31. Mahasen A. Radwan “Preparation and in vivo evaluation of parenteral metoclopramide –
loaded poly(alkylcyanoacrylate) nanospheres in rats” Journal of
Microencapsulation18:467-477(2001). ISI
32. Mahasen A. Radwan, Iman Y. Zaghloul, Badraldin M. Al-Hadiyah, and Khalil I.
AlKhamis “The influence of fluvoxamine administration on glibenclamide
pharmacokinetics after multiple oral dosing in rats” Saudi Pharmaceutical Journal, 8: 116-
121 (2000). ISI
33. Mahasen A. Radwan"Zidovudine, diclofenac, and ketoprofen pharmacokinetic
interactions in rats" Journal Pharmacy and Pharmacology, 52:665-669 (2000). ISI
34. S. Elkheshen and M. A. Radwan ”Sustained release microspheres of metoclopramide
using poly(D,L-lactide-co-glycolide) copolymers” Journal of Microencapsulation,
17(4):425-435 (2000). ISI
35. Mahasen A. Radwan, Iman Y. Zaghloul, and Zinat H. Aly, “In-vivo performance of
parenteral theophylline - loaded polyisobutylcyanoacrylate nanoparticles in rats”
European Journal Pharmaceutical Science, 8:95-98 (1999). ISI
36. Mahasen A. Radwan “Determination of metoclopramide in serum by HPLC assay and its
application to pharmacokinetic study in rat” Analytical Letters, 31 (14): 2397-2410 (1998).
ISI
37. Mahasen A. Radwan, Iman Y. Zaghloul, Ahmed I. Radwan, Zinat H. Aly, “Multiple –
Dose pharmacokinetics of long -acting oxytetracycline in Brucella Melitensis – infected
sheep”, International Journal of Pharmaceutics, 160:91-7 (1998). ISI
38. Iman Y. Zaghloul and Mahasen A. Radwan “High Performance Liquid Chromatographic
Determination of Tramadol in Pharmaceutical Dosage Forms” J. of Liquid
Chromatography, 20:779-87 (1997). ISI
39. Iman Y. Zaghloul, Zinat H. Aly and Mahasen A. Radwan “Effect of Ciprofloxacin on the
Hypoprothrombinemic Activity of Warfarin in Rats”, International Journal of
Pharmaceutics, 131 (2):131-6 (1996). ISI
40. Mahasen A. Radwan, Zinat H. Aly, and Iman Y. Zaghloul, “Effect of Experimental Liver
Damage by CCL4 on the Pharmacokinetics of Zidovudine in Rats” Saudi Pharmaceutical
Journal, 3:90 - 94 (1995). ISI
41. Mahasen A. Radwan “HPLC Assay of Theophylline and Zidovudine in Rat Serum” J. of
Liquid Chromatography, 18 (16):3301-3309 (1995). ISI
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42. Mahasen A. Radwan “In vitro Evaluation of Polyisobutylcyanoacrylate Nanoparticles
as a Controlled Drug Delivery System of Theophylline”, Drug Development and Industrial
Pharmacy, 21(20): 2371-75 (1995). ISI
43. Mahasen A. Radwan, James C. Price, and Randall L. Tackett, “IN VITRO Release of
Disopyramide from Cellulose Acetate Butyrate Microspheres” Drug Development and
Industrial Pharmacy, 21: 1453-62(1995). ISI
44. M. Radwan “In Vivo Screening Model for Excipients and Vehicles Used in Subcutaneous
Injections”, Drug Development and Industrial Pharmacy, 20: 2753-62 (1994). ISI
45. M.A. Radwan “Stability-Indicating HPLC Assay of Zidovudine in Extemporaneous
Syrup”, Analytical Letters, 27: 1159-1164 (1994). ISI
46. Mahasen A. Radwan, James C. Price, and Randall L.Tackett, "Analysis of Disopyramide
by HPLC with UV Detection", Analytical Letters, 20:1125-31 (1987). ISI
47. H. Won Jun and Mahasen A. Radwan, "Determination of Oxamniquine in Plasma
Samples" Analytical Letters, 18:(1985). ISI
CHAPTERS
1. Mahasen A. Radwan, Nagwa H. Foda, and Omar A. Al Deeb “Mebeverine Hydrochloride”
Analytical Profiles of Drug Substances and Excipients, 25: 165-207 (1998).
2. Nagwa H. Foda, Mahasen A. Radwan, and Omar A. Al Deeb “Fluvoxamine Maleate”
Analytical Profiles of Drug Substances and Excipients, 24:165-208 (1996).
PRESENTATIONS – Abstracts for Oral or Posters
1. M.A. Radwan “Clinical Pharmacokinetics in Egypt: Where we are!” The International
Conference of Faculty of Pharmacy, Egyptian Russian University (ERU): Recent Trends in
Pharmaceutical Sciences” April 28-29, 2018 – Air Defense House Cairo Egypt.
2. M.A. Radwan, Bushra T. ALQuadeib, Lidija Siller, Matthew Wright, Benjamin Horrocks
“Bioavailability and Toxicity of Novel Oral Delivery System of Amphotericin B loaded to
PEGylated Polylactic-Polyglycolic Nanoparticles in Rats”43rd Annual Meeting & Exposition
of the Controlled Release Society, July 17 – 20, 2016, at the Washington State Convention
Center in Seattle, Washington, U.S.A.
3. A.S. Almurshedi, M.A. Radwan, G. Hutcheon, I. Saleem, M. Elkatib “Development of
Novel Pulmonary Liposomal Delivery System of Afatinib Targeting Non-Small Cell Lung
Cancer: In Vitro Characterization” 43rd Annual Meeting & Exposition of the Controlled
Release Society, July 17 – 20, 2016, at the Washington State Convention Center in Seattle,
Washington, U.S.A.
4. Bushra T. ALQuadeib, M.A. Radwan, Lidija Siller, Matthew Wright, Benjamin Horrocks
“Toxicity in rats and in vitro Efficacy of Amphotericin B Nanoparticles formulations” 43rd
Annual Meeting & Exposition of the Controlled Release Society, July 17 – 20, 2016, at the
Washington State Convention Center in Seattle, Washington, U.S.A.
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5. M. A. Radwan, W. M. Mandour, M. M. El Khatib, I. A. Alsarra Pharmacokinetics of
Pioglitazone Loaded to Buccoadhesive Patches in Dogs Using UPLC MS/MS. AAPS Annual
Meeting, November 10-14, 2013, San Antonio, TX, USA.
6. M. A. Radwan, B. T. al-Quadeib, L. Siller, E. Mutch, A. Alshaer, B. Horrocks, Therapeutic
amphotericin B monitoring in Saudi ICU patients using UPLC MS/MS assay. AAPS Annual
Meeting, November 10-14, 2013, San Antonio, TX, USA.
7. Nayira A. Abdel Baky, Nouf M. Al-Rasheed, Nawal M. Al-Rasheed, Iman Y Zaghloul, and
Mahasen A. Radwan The potential cardioprotective effect of alpha lipoic acid on
isoprotrenol induced myocardial infarction in rats. May 2009 The Joint Meeting of Britches
pharmacological Society: New drugs in pharmacological research, Dresden, Germany,
8. Mahasen Radwan, Amal Fatani, Nouf Alouda “Insulin Oral Delivery of Insulin, Is There A
Hope?” February 2009 1st International Conference on Biotechnology, Riyadh.
9. Mahasen Radwan, Samia Omar "Bioavailability of in situ-gelling and mucoadhesive
ketoconazole liquid suppository in the rat" (R6109) 2006 AAPS Annual Meeting (10/28/2006
- 11/2/2006) San Antonio, TX, USA.
10. Mahsen Radwan, May Al Jaser, Zahra Al Rayes Mohammed Mubarak Pharmacokinetics
and Nephrotoxicity of Pentavalent Antimony after Acute and Chronic Administrations of 80
mg/kg for 3 weeks in the Hamster" (T2335)2006 AAPS Annual Meeting (10/28/2006 -
11/2/2006) San Antonio, TX, USA.
11. Bushra T. Al-Quadeb, Mahasen A. Radwan, Heba H. Abdine, Hassan Y. Aboul-Enein and
Kenichiro Nakashima “Stereoselective HPLC assay of Donepezil Enantiomers in tablets and
plasma and its Application to pharmacokinetics in rats” 9th International Pharmaceutical
Sciences Meeting and Exposition, December 17-21, 2005 in Riyadh, Saudi Arabia.
12. Heba H. Abdine, Mahasen A. Radwan, Hassan Y. Aboul-Enein “A validated chiral HPLC
Method for Method for Determination of Mebeverine HCL Enantiomers in Pharmaceutical
dosage forms and spiked rat plasma.” Podium, 9th International Pharmaceutical Sciences
Meeting and Exposition, December 17-21, 2005 in Riyadh, Saudi Arabia.
13. Mahasen A. Radwan, May H. Al Jaser, Zahra R. Al Rayes "The Effect of InducedDiabetes
and Cutaneous Leishmania infection on the Pharmacokinetics of Antimony(v) after Acute and
Chronic Administrations in the Hamster" April 10-15 (2005). Worldleish 3 –Sicicily –
Palirmo – Italy
14. Mahasen A. Radwan, May H. AL Jaser and Iman Y. Zaghloul "Pharmacokinetics and Tissue
Distribution of Antimony(V) After Multiple Intramuscular Administrations in the Hamster"
Worldleish 3 –Sicicily – Palirmo - Italy April 10-15 (2005).
15. Mahasen A. Radwan, Nouf M. Aloudah “HPLC assay of fluconazole and its application to
patients with early septic shock” Annual Meeting of the American-College-of-
ClinicalPharmacy, OCT 24-27, Dallas, TX, USA (2004). Pharmacotherapy, Volume: 24
Issue: 10: 1460 (Abstract: 268) OCT 2004.
16. Hassan Y. Aboul-Enein, Rajaa F. Hussein, Mahasen A. Radwan, Sameer Al-Rawithi
“Biotin dissolution from pharmaceutical dosage forms using an automated HPLC
system”2004.
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17. M. A. El-Sherbeny, H. S. Al-Salem, M. A. Sultan, M. A. Radwan, H.A. Farag, and H. I. El-
Subbagh, “Design, Synthesis, Investigation of Brain Delivery Model for Anticancer
Compounds” 7th International Conference on Chemistry and its Role in Development.
Mansoura & Sharm El-Sheikh, April 14-17, 2003.
18. Hassan Abu El-Enein, Rajaa F. Hussein, Mahasen A. Radwan, Ahmad Yusuf, Wijdan
ALAhmadi, and Sameer Al-Rawithi”Tamsulosin dissolution from pharmaceutical dosage
forms using an automated hplc system” The 1st International Congress Pharmaceutical &
Drug Industries Division National Research Centre – Towards Safe and active Drug. March
24-26, Cairo Egypt 2003.
19. S. Elkheshen and M. A. Radwan”Sustained release microspheres for metoclopramide using
poly(D,L-lactide-co-glycolide) copolymers of different inherent viscosity” Saudi
Pharmaceutical Society, The Pharmacy Profession in the 21st Century, Riyadh, October
1999.
20. Iman Zaghloul, Mahasen Radwan, Zinat H. Aly, Ahmed I. Radwan, ”Pharmacokinetics of
a
Long - acting Oxytetracycline in Brucella melitensis-infected sheep”, Saudi Biological
Society, Sixteenth Annual Meeting on Biological Natural Resources in Kingdom of Saudi
Arabia, March 1995.
21. Mahasen A. Radwan, Bobby Bryant and Erh Chi Huang, “Development of a Sensitive
HPLC Assay for Lorazepam to Monitor Plasma Levels in Neonates." American Association
of Pharmaceutical Scientists, Washington DC, November, 1991, USA.
22. Mahasen A. Radwan, "HPLC Stability - Indicating Assay of AZT in Liquid Dosage Form."
American Association of Pharmaceutical Scientists, Washington, DC, November, 1991,
USA.
23. D. Goldman, M. Radwan, F. Vane and S. Dixit, "In Vitro and In Vivo Release Characteristics
of Sustained Release Subcutaneous Formulations" American Association of Pharmaceutical
Scientists, Atlanta, October, 1989, USA.
24. Mahasen A. Radwan, David Goldman, Charanjit R. Behl, Saran Kumar, and Sara L.
Friedlander, "Development of In Vitro Release Method For Semisolid Products” American
Association of Pharmaceutical Scientists, Orlando, November, 1988.
25. David Goldman, Mahasen A. Radwan, Suresh C. Dixit, and Peter C. Will, "Evaluation of
InVitro Drug Release From Rectal Preparations" American Association of Pharmaceutical
Scientists, Orlando, November, 1988, USA.
26. Mahasen A. Radwan, James C. Price, and Randall L. Tackett, "In Vitro / In Vivo Correlation
of Disopyramide Oral Sustained Release Formulations, "American Association of
Pharmaceutical Scientists, Orlando, November, 1988.
27. Mahasen A. Radwan, James C. Price, and Randall L. Tackett, "Microencapsulation of
Disopyramide for Oral Sustained Release Dosage" Graduate Research Association of
Students in Pharmaceutics, West Virginia, June, 1987.
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28. Mahasen A. Radwan, James C. Price, and Randall L.Tackett, “Effect of Formulation
Parameters on Characteristics of Cellulose Acetate Butyrate Microcapsules of Disopyramide,
"American Association of Pharmaceutical Scientists, Boston, June, 1987.
29. Mahasen A. Radwan, James C. Price, and Randall L Tackett, “Pharmacokinetic of
Microencapsulated Disopyramide in Dogs" American Association of Pharmaceutical
Scientists, Boston, June, 1987.
30. Mahasen A. Radwan and H.Won Jun, “Pharmacokinetic and Tissue Distribution Studies of
Oxamniquine in Animals" American Association of Pharmaceutical Scientists, Washington
DC, November, 1986.
31. Mahasen A. Radwan and H.Won Jun, "High Performance Liquid Chromatographic
Determination of Oxaminquine in Plasma and Tissue Homogenate" Graduate Research
Association of Students in Pharmaceutics, New Jersey, July, 1985.
EXTRACURRICULAR ACTIVITIES
Besides attending most of the available meetings or conferences (In/out the University Campus),
and the available International Meeting/Conferences (according to our teaching load) the following
is a selection of recent Lectures/Seminars which were given:
February 7, 2016: A 30 min talk of “How to write a research proposal” to my “Future
researcher” group at College of Pharmacy.
January 21, 2016: A two-hour seminar on “Writing a Scientific Research Paper” to the Health
Foundation Year students, Princess Nourah bint Abdulrahman University.
August 25, 2015: A two-hour seminar on “Learn How to Learn” to the Health Foundation Year
students, Princess Nourah bint Abdulrahman University.
June 6, 2015: A three-hour Workshop on “How to use Excel in your work” to all the Health
Foundation Year Staff members, Princess Nourah bint Abdulrahman University.
December 30, 2014: A three-hour workshop of “Factorial Design and SPSS” to TA, lecturers and
Faculty members of College of Pharmacy, Princess Nourah bint Abdulrahman University.
March 14, 2014: A three-hour workshop of “How to publish your research” to Faculty members
of College of Pharmacy, Princess Nourah bint Abdulrahman University.
March 4, 2014: A seminar on “The use of Chi Square in Data Analysis” to Faculty members of
College of Pharmacy, Princess Nourah bint Abdulrahman University.
December 3-5, 2013: Workshop on “SPSS application in Health Sciences” for Faculty members
at Princess Nourah bint Abdulrahman University (A 3-day workshop).
April 2013: Research day workshop for undergraduate students before starting their graduation
research project. College of Pharmacy, Princess Nourah bint Abdulrahman University.
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April 8-9/2012: Workshop on “Getting Started with SPSS”, for Faculty members at Princess
Nourah bint Abdulrahman University (A 2- day workshop).
May 28- June 1st,2011: Nanotechnology Application Workshop: (Presented three 2-hr lectures
at Princess Nourah bint Abdulrahman University.
February 20, 2011 “An Overview of Zetasizer (nano) Utilization in Pharmaceutical
Applications” a two hour lecture in “Particle characterization by using Zetasizer: Theory and
Application workshop” Al Malaz Central Laboratory.
May 2010: Research day workshop to introduce undergraduate students to research and area of
research available in King Saud University.
March 2009: Workshop: “Clinical Pharmacokinetics Review” at Saudi Pharmaceutical Society
Midyear Meeting, Jeddah.
May, 2008: “Nanotechnology: A New Era in Drug Delivery” Riyadh Military Hospital, Riyadh.
May 7th, 2008: Workshop, "Nanotechnology: A dream or reality in drug delivery and
Cosmetics” King Saud University.
May, 2006: Workshop: "Tips on Getting Published" seminar in "How to Publish?!“ Research
Center King Saud University.
August 1st, 2006. "Clinical Pharmacokinets of Low E Drugs" Lecture in Workshop of "Clinical
Pharmacy for graduate pharmacists“, College of Pharmacy, Cairo University, Egypt,
November 2004: " The effect of deodorants on Human and Environment", Seminar in What
is hazards to your health Symposium at King Saud University, girls section.
July 29, 2003: "Utilization of Polyalkylcyanoacrylate Nanoparticles (PAN) as a Drug Delivery
System" , Seminar, Free University, Berlin, Germany
July, 2003 "Governmental Rules and Regulations for marketing new drugs“ Guest speaker
for 30 minute TV Show "Society and Medication" in Channel 2 Saudi TV. Saudi Arabia
November, 2003: Symposium on “Natural Products Advantages and disadvantages”, lecture on
“Pharmacokinetics of herbal medicine: Gingko Biloba and St. John’s Wort” Seminar in
, King Saud University.
July 13, 2002. A lecure on "Utilization of Polyalkylcyanoacrylate Nanoparticles (PAN) as a
Drug Delivery System". Seminar, Free University, Berlin, Germany.
October 2001: " How to utilize computer in teaching" Workshop offered to faculty members
and teaching assistants and graduate students, King Saud University.
October 23, 2000 “A female pharmacist can make a difference”, Seminar in the University and
Community Week, King Saud University.
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September 27, 1998: "The other face of Deodorants: Cancer and the increase in the heart
beats and difficulty in breathing” National News Paper, AL RIYADH, 11052:
pp. 29.
September, 1998: "Do we have to be worried from using deodorants?" Seminar, King Saud
University
October, 1996: "What the body will do to a drug?" Seminar, King Saud University.
REFERENCES
They will be furnished upon request.