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Improving the pig’s immune status, productivity and efficiency by enhancing gut health
Rainer Rauch4Mix International
011 866 2900 / 082 604 [email protected]
www.4mix.co.za
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Overview
• Anatomy and digestion• Metabolic Efficiency• How do we maximise Metabolic Efficiency?
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Anatomy and digestion• The main parts of the digestive tract
– 1. Stomach– 2. Small Intestine – 3. Cecum/Large Intestine– 4. Liver (and associated organs)
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Anatomy and digestion
• 1. Stomach– Secretion of enzymes and
hydrochloric acid • pH = approx 2
– Main enzymes = proteolytic (protein digestion)
– Low pH important for• Partial / total eradication of microbes• Hydrolysis of proteins • To optimise pH-dependant protease
enzyme function
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Protein digestion in stomach
Acid
Acid dependant proteolytic enzymes
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Small Intestine• 2. Small Intestine
– Alkaline secretions results in ~ neutral pH– Digestion of smaller protein chains (polypeptides) into amino acids– Absorption of amino acids– Bile secretion to emulsify fats, similar to detergent action (break apart
globules to allow for enzyme attack)
~ neutral pH
~ neutral pH dependant protease enzymes
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Cecum/ Large Intestine• 3. Cecum/ Large Intestine
• Fermentation chamber• No enzyme secretion
– therefore enzyme activity due to “carry over” from small intestine or microbial enzyme production
• Similar in many ways to rumen• Microbial fermentation = 8-16% of
digestion in pig• A low protein digestibility in the stomach /
small intestine can lead to higher protein levels in the large intestine and an “E. coli friendly” environment
• E. coli has been related to oedema disease
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Liver• 4. Liver
– Metabolism of absorbed nutrients – Storage organ for many minerals / certain
vitamins– Energy storage to control blood glucose
(glycogen can be approx 8% of liver fresh weight)
– Bile production for effective fat digestion
– Main site for detoxification (e.g., mycotoxins)– Synthesis of blood components– Hormone manufacture e.g., IGF (Insulin-Like
Growth Factor)
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“Metabolic Efficiency”Gross Energy Total energy of feed
Faecal Energy Digestible Energy
(DE) Energy "available" in blood
Urine Energy
Methane Energy Metabolisable Energy
(ME) Energy available at tissue levelHeat Energy
(during metabolism) Net Energy
(NE) Energy deposited in tissue /
end product (meat, milk, eggs)
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How do we maximise Metabolic Efficiency?• First focus on on-farm solutions
• Quality of raw materials– Digestibility– Voluntary feed intake– Mycotoxins, etc
• Correct and up to date formulations• Genetics• Feed processing • Management
– Temperature / humidity– Quality of housing / floors– Stress factors (e.g. overcrowding)– Well-trained staff
• Disease
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How do we maximise Metabolic Efficiency?
• What can we offer?
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How do we maximise Metabolic Efficiency?
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Acidpro• Unique Organic Acid blend
researched and developed in South Africa for local conditions
• Unique combination of organic acids improves digestibility and feed efficiency through several mechanisms
• Improved pH conditions to allow for higher rate of protein digestion• Reduced protein in hindgut • Reduced risk of E. coli and associated endotoxin related disease
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Acidpro• Acidpro is more than just an
ordinary organic acid blend
• Also contains pre- and pro-biotics to ensure that beneficial micro-organisms are established and that they proliferate
• Competitive exclusion of harmful micro-organisms
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ClexVit• ClexVit is a mycotoxin
binder with a difference
• 3 pronged approach• 1. Toxin binding• 2. Toxin deactivation• 3. Immune stimulation
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ClexVit• ClexVit is a mycotoxin binder
with a difference
• 1. Toxin binding• Different types of clay• 4 different yeast cell walls (exo-
and endo-toxin binding)• Nanotechnology / advanced
grid spacing– Large surface area
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ClexVit• ClexVit is a mycotoxin • binder with a difference
• 2. Toxin deactivation• Enzyme forming yeasts• Liver stimulating additives
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ClexVit• ClexVit is a mycotoxin
binder with a difference
• 3. Immune stimulation• Natural vitamin E• Organic Zinc and Selenium• Phosphorus improves
carbohydrate and protein metabolism
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ClexVit• ClexVit is a mycotoxin
binder with a difference
• 1 – 6 kg / ton depending on type of pig and severity of mycotoxin problem
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What makes us unique?
• Up to date science to research and develop on-farm solutions
• Strategic symbiosis of products
• Honest on-farm technical support
• Your success is our success
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Thank You