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HOW DID IT ALL START ?
DR. MOHAMMAD ABBAS
Assistant Professor& Orthopedic ConsultantFaculty of MedicineKing Abdulaziz University
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NOVEMBER 2009
KNEE COURSE BY SMITH & NEPHEW IN TOURS, FRANCE.
THE TRUFIT PLUG FOR FOCAL CHONDRAL DEFECT WAS INTRODUCED BY DANIEL SARIS
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FOR FOCAL CHONDRAL DEFECT
TRUFIT PLUG
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MSCs
?FOR LARGER AREA OF CARTILAGE DEGENERATION ? TOTAL OSTEOARTHRITIS
TRUFIT PLUG
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JANUARY 2010
THE IDEA AND PROCESS OF STARTING A SCIENTIFIC CHAIR THROUGH RACI @ KAU
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A long tedious process to fulfill the RACI requirements
Sponsor. Distinguished stem cell professor. 3 years detailed plan. Organizational chart. Web page.
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“ There is a huge gap between clinicians and scientists ”
Building up the team
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Biochemistry professor. Consultant Hematologist Consultant Radiologist. PhD scientist in stem cell biology Orthopedic surgeons. Lab. specialist with
master in tissue culture.
Building up the team
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الكرسي مشـــرفعباس. محمد د
أستـاذ الكرسي
أعضاء البحثية الكرسي المجموعات
مختبر الخاليا الجذعية
اإلدارة المالية
. وائل. د اكافينا
فاتن. دالسايس
. ممدوح. د أقاري . عطا. حازم د أ
محمد. دالكاف
مجموعة العظام أبحاث
عباس. محمد دعليشودري. د
درويش. حسام دحمدي. عمرو دالكاف. محمد د
مجموعة أمراض أبحاث
الدم السايس. فاتن د . قاري. ممدوح د أ
كالميجام. دجوثمان
السهلي. حنين أ
أبحاث مجموعةاألشعة
قطب. ممدوح د
أبحاث مجموعةالحيوية الكيمياء
. عطا. حازم د أ
. ممدوح. د أقاري
كالميجام. دجوثمانرهام. أالنونو
حنين. أالسهلي
بالتعاون مركز معالبحوث واالستشارات
Organizational chart
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3 years detailed plan
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Inauguration was on 22 Feb. 2012.
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ESTABLISHING THE STEM CELL LAB. IN THE OPRATING THEATRE
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Establishing a stem cells unit in CEGMR in KFRMC
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Isolation & characterization of MSCs
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Team members are regularly attending ICRS world congress
2015
2013
2012
Team Development
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Participation in ICRS courses
Radiologist MRI T2 mapping of cartilage course in Vienna 2012.
Orthopedic surgeons learning surgical procedures for cartilage regeneration.
Team Development
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1- Isolation and Characterization of Mesenchymal Stem Cells from Bone Marrow of Osteoarthritis patients
2- Epigenetic analysis of osteoarthritis patients
3- Exome sequence analysis for osteoarthritis patients
4- Evaluation of ex-vivo cartilage regeneration with mesenchymal stem cells derived from the human bone marrow (hBM-MSCs) and synovial fluid (hSF MSCs) from osteoarthritis patients
Molecular Hematology Research
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1- EFFECT OF ADRENALINE & VOLTAREN ON VIABILITY and PROLIFERATION of HUMAN MESENCHYMAL STEM CELLS
2- EFFECT OF MARCAINE & DEXAMETHASONE ON VIABILITY and PROLIFERATION of HUMAN MESENCHYMAL STEM CELLS
00.20.4
Effect of Adrenaline on the Viability and Proliferation
of Human MSCsMean
OD
0.14
0.17
Effect of Marcaine on the viability and proliferation
of human MSCsMean
OD
Biochemistry Research
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The focus was on building up Articular Cartilage
Orthopedic Animal Research
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Two projects done on rabbits for focal defects
Orthopedic Animal Research
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Most recent research focuses on Induced Total Surgical Arthritis in Rabbits using
MSCs + Scaffolds
Orthopedic Animal Research
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6 monthly report A yearly presentation to RACI
committee A yearly financial report
Fulfilling RACI follow up
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A yearly meeting with the sponsor
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