HERBAL REMEDIES, SUPPLEMENTS AND CBD: ARE THEY SAFE?DO THEY WORK?
TREVOR CHRIST, PHARMD, BCOPType to enter a caption.
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
OBJECTIVES
▸ Provide key definitions and statistics
▸Describe regulatory oversight of herbal supplements
▸Discuss potential benefits and harms of herbal supplement and CBD use in lymphoma patients
▸ Provide conclusions, resources, and parting advice
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
DEFINITIONS
▸Dietary Supplements
▸ Complementary medicine
▸Alternative medicine
https://nccih.nih.gov/health/supplements. Accessed August 14, 2019.
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
REGULATORY OVERSIGHT OF DIETARY SUPPLEMENTS
▸Dietary Supplement and Health Education Act (DSHEA) of 1994
▸ Federal Drug Administration’s (FDA) responsibilities
▸ Federal Trade Commission’s (FTC) responsibilities
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
COMPARE TO FDA APPROVED PRESCRIPTION DRUG
Phase IIPre-clinical Phase I Phase III
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
ANATOMY OF LABEL
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
DIETARY SUPPLEMENTS▸ The Good
▸Added sense of control
▸Many benefits for various CAM practices (Massage, Aroma therapy, etc.)
▸Nutritional supplementation for vitamin deficiency
▸ The Bad
▸ The Ugly
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
DIETARY SUPPLEMENTS▸ The Good
▸ The Bad
▸ Limited benefits in cancer population
▸ Safety
▸ Drug interactions
▸ Cost
▸ Misinformation
▸ The Ugly
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
DRUG INTERACTIONS
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
DIETARY SUPPLEMENTS▸ The Ugly
▸ Severe liver damage
▸ Increased risk of death in patients choosing alternative medicine over conventional medicine (patients with curative cancers)
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
CBD OIL
▸What is it?
▸What do we know about it?
▸ Is it legal?
▸ Is it safe?
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
WHAT YOU CAN DO
▸ If interested in an herbal supplement, talk to your doctor or pharmacist
▸Don’t exceed recommended doses
▸ Keep track of what you take and only start one supplement at a time.
▸ Research the expected onset of action of the effect you’re looking for (might not always be available) and decide if it’s worth continuing to take
▸ Choose brands with either consumerlabs.com or U.S. Pharmacopeia convention
▸Don’t just trust label and other marketing material, talk to your doctor or pharmacist and research validated websites
▸ Check safety alerts on the FDA website
HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?
RESOURCES
▸ https://ods.od.nih.gov/factsheets/list-all/
▸ https://www.mskcc.org/cancer-care/diagnosis-treatment/symptom-management/integrative-medicine/herbs/search
HERBAL REMEDIES, SUPPLEMENTS AND CBD: ARE THEY SAFE?DO THEY WORK?
TREVOR CHRIST, PHARMD, BCOPType to enter a caption.