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Health Sciences South Carolina: A Statewide Collaborative Learning Health System
● Focus: University—Health System collaborations to advance health● Approach: Technology Empowered Communities of Practice ● Collaborative Programs:○ Integrated research data repository○ Surgical quality collaborative○ Emergency department health
information exchange ○ e-IRB and multi-site IRB reliance
Current data contributors include MUSC, Palmetto Health System and Spartanburg Health systems. Greenville Health System data is available but the health system is no longer an active member of HSSC.
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The Problem: Research Data at the Hospital Level
● Clinical systems are typically integrated in point-to-point connections
● Research data is stored in islands
● Limited connectivity between these domains
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● This architecture scales badly across multiple organizations
The Problem: Research Data at the State Level
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Collection AccessStorage
Data Scope: DemographicsDiagnosesProcedures Medication ordersMedication adminLabs
Data Feed Consolidation& Mapping
Operational Data Store
(HTB)
Clinical Data Warehouse
(CDW)
Data Marts &
Registries
RESEA
RC
HC
LINIC
AL
Anonymizedi2b2
Cohort Analysis
MPI
Healthcare Institutions
Spartanburg Regional Health System
Palmetto Health
Medical University South Carolina
Data Feed Types: HL7, 837A, CSV
Current state: Single Integrated Database
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Information-at-Rest to Information-in-Motion
6
Information platform for collaboration
• Federated provider databases• Multiple linked data models• API for access by EHRs and other apps• Research master ID integrated with
institutional data• Information enrichment subscriptions
(deaths, claims, environmental data, ADT events)
• Integrated open source analytics (OMOP/OHDSI)
Current Future
Information resource for research• Single central database • Proprietary data model (HL7 v3RIM
derived)• Periodic database releases• Governance based access data by
honest brokers• Limited access for clinical applications
(no ”API”)• Export for analytics to separate platform
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Smile CDR fro Sympatico
● Complete FHIR-based Clinical Data Repository Solution
● Powered by HAPI FHIR
● Launched as a commercial offering in 2016
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Collaboration Architecture for the Future
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Goal: Platform for Cross-enterprise Data Integration for Collaboration, and Research
Condition List app provides longitudinal view of conditions across participating organizations
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Maintain Clients’ Data in Different CDMs for CollaborationResearch collaboration requires the ability to maintain data in multiple clinical data models without excessive maintenance costs. Smile CDR support the use of FHIR subscriptions between data stores to maintain data multiple formats
SmileCDR
PCORnetCDR
OMOP CDR
ACTSCDR
InstitutionalClinical Data
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• OMOP CDM is a Common Data Model + Standardized Vocabulary OHDSI is a multi-stakeholder,
interdisciplinary collaborative with thousands of members
OHDSI supports the OMOP CDM and set of open source analytics tools.
OHDSI runs an ongoing set of observational studies evaluating pharmacotherapies and predictive analytics models.
Example CDM for Collaboration: OHDSI
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Open Source Analytics Using OHDSI/OMOP
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Collaboration Architecture for the Future
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Goal: Enrich data with Information Subscriptions
ED Notification App provides cross-enterprise notification when some patients present at any participating Emergency Room (todo: add screenshot)
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Social determinants of health data subscriptions from geolinkedsources
Automatically Enrich Member Databases with New Linked Information from External Sources
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Information Subscriptions: Environmental Data from Networked Regional Sensors
Air pollution data (geolinked) vs. asthmaadmissionsto EDs
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Future Plans: Expanded Scope● Current Scope:
○ Patients, Encounters, Conditions, Vital Signs, Insurance○ 2 Hospital Systems○ OHDSI linked CDM○ ADT notifications○ Research MPI and mortality data subscriptions
● Under Development:○ Laboratory Results○ Medication Orders and Administration○ Additional Hospital Systems○ Geolinked data