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Example of acute and chronic inflammation
PROBLEM BASED LEARNING (PBL)
PREPARED BY: MUHAMMAD ARIFF B. MAHDZUB
BACHELOR MEDICINE AND SURGERY (MBBS)
UNIVERSITY COLLEGE SHAHPUTRA, KUANTAN
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Example of diseases associated with acute inflammation
• acute bronchitis
• sore throat from a cold or flu
• acute appendicitis
• acute tonsillitis,
• acute infective meningitis
• acute sinusitis
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Acute bronchitis
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Sore throat
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Acute appendicitis
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Acute tonsillitis
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Acute infective meningitis
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Acute sinusitis
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Example of diseases associated with chronic inflammation
• Alzheimer’s Diseases
• Rheumatoid Arthritis
• Chronic peptic ulcer
• Asthma
• Hypersensitivity
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Alzheimer’s disease
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Rheumatoid arthritis
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Rheumatoid arthritis
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Chronic peptic ulcer
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Asthma
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Hypersensitivity
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Body Reaction Towards
Hypersensitivity
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Hypersensitivity
A state of altered reactivity in which the body reacts with an exaggerated immune response to a foreign substance
There are 4 types :
1. Type I (Anaphylactic) reactions2. Type II (Cytotoxic) reactions3. Type III (Immune complex) reactions4. Type IV (Cell-mediated) reactions
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Type 1 (Anaphylactic) reactions
• Occur within minutes of exposure to antigen
• Allergen attached to IgE antibodies
• IgE binds to mast cells and basophils, causing them to undergo degranulation and release several
chemical mediators :
• histamine – dilates and increases permeability of blood vessels (swelling & redness)
• Prostaglandins – contraction of smooth muscle & increased mucus secretions (control blood pressure)
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