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Current efforts on Mycoplasma hyopneumoniae control in
reproductive herds
Maria PietersVeterinary Population Medicine department
& Veterinary Diagnostic Laboratory
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Outline
• Where are we at?
• Current efforts
• Mycoplasma Task Force
• Take home message
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• M. hyopneumoniae is highly prevalent in
the USA and the world
• Disease control is less than ideal
• Eradication of disease is a growing trend
• Antibiotic free production is increasing
Where are we at?
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Private practice
Production systems
Academia
Industry
Mycoplasma control issues affect all of us
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Current efforts
• Gilt acclimation initiative
• Economic evaluation of disease and freedom of
• Elimination programs
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Initiative for a collaborative group of U.S. industry and academic leaders with demonstrated interest on aspects related to Mycoplasma infections in swine
The objective of the Task Force is to discuss current strategies, procedures, and tools used in the swine industry, and to make recommendations based on collaborative discussions and review of literature and field information
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Main aspects to focus on
• Status of the problem• Case definition• Current control methods• Elimination
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Status of the problem
• Mycoplasma infections still an issue• Limiting factor in antibiotic free production • Lack of information for common
understating and approaches for disease control
• Lack of information disclosure • Status of diagnostics
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Problematic
• Lack of diagnostics
•Clinical disease in pigs
Not problematic
•Pigs clinically “quiet”
• Serology low in P3s and up
•Not rising S/P values after purposeful exposure
•PCR- 15 woa• Serology- 20
woa
In transition
• Longer than 12 months as a “Not Problematic” farm
•PCR negative gilts at farrowing
Negative
•Post depopulation/ repopulation
•No evidence of antibody response
Case definition
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Current control methods
Management
Medication
Vaccination
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Vaccination
• New vaccine technologies• Gilt vaccination strategies• Sow vaccination:
– Revisiting the maternal interference concept– Characterizing immune response post-
vaccination in sows
• Piglet vaccination
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Medication
• Guidance on antibiotic use• Prevalence threshold for treatment in the
sows (cost-benefit analysis)• Prevalence at weaning threshold for piglet
treatment• Antimicrobial resistance
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Management
• Gilt management:– Continuous flow – All-in/all-out
• Batch production (wean age)• Parity segregation • Matching management with case definition
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Elimination
• Economics• Strategies• Acclimation – Exposure methods• Shortening time for elimination• Is low prevalence good enough?• Quantifying risk of lateral transmission
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Elimination
• Animal welfare• Advantages of Mycoplasma negative
production• Effect on antibiotic usage• ROI• Co-infections as confounding factors
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Next steps
• Disclosing information
• Getting organized with producers and
practitioners for generation of information
• Field trials
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Take home message
- Exciting times!
- Information needed interest to generate new information
- Be open, work together, and share your results!