Syllabus for B.Sc. (Honors) in Chemistry
Session: 2016-2017, 2017-2018 and 2018-2019
Department of Chemistry
Faculty of Science
Mawlana Bhashani Science and Technology University
Santosh, Tangail-1902
Page 1 of 72
Distribution of Courses and credits:
The syllabus for the 4-year B.Sc. (Honors) in Chemistry degree consists of 160
credits and will be divided into eight semesters. Every two semester will cover an
academic year. For each semester, the examinations will be held at the end of the
semester. A candidate for the above mentioned degree have to take total 75
(seventy five) courses covering 160 credits. The summary of the syllabus is given
below:
96 credits of Chemistry theory courses (Major)
28.5 Chemistry practical courses (Major)
3.5 credits oral course (Major)
6 credits Internship at Industry or Research Organization/Project work
10 credits Mathematics theory courses (Integrated)
8 credits Physics theory courses (Integrated)
2 credits Biology theory course (Integrated)
2 credits Biochemistry theory course (Integrated)
2 credits Microbiology theory course (Integrated)
2 credits English theory course (Integrated)
________________________________________________________
Total = 160 credits
The CHEM-4207 Internship at Industry or Research Organization/ Project work
course will be meant for giving practical training to the students in an appropriate
chemical/pharmaceutical industry or doing short-term research work offered by
the teachers of the department or in an appropriate research institution. The
department will assign whether a candidate have to accomplish internship at
Industry or Research Organization or project work according to the availability of
the position.
Selected Part of the Academic Ordinance for B.Sc. (Honors) Degree
Duration of the program of study: The program of the study for the degree
of B. Sc. Honors in Chemistry shall extend over a period of 04 (four) academic
years. The students cannot be allowed to complete their B.Sc. (Hons.) degree in
more than 06 (six) academics years. One year consists of 02 (two) semesters. So
the whole program consists of 08 (eight) semesters.
Duration of Semesters and Courses:
The duration of each semester shall be as follows:
i) Class to be held 14 Weeks
ii) Recess before the date of commencement of
semester final examination 2 Weeks
iii) Duration for conducting each semester final
Examination and completion of results 7 Weeks (4 weeks
for Examination
and 3 weeks for
publication of the
results)
Total 23 Weeks
Page 2 of 72
Assignment of credits:
Theory Courses: A three (3) credit course will involve at least three classes of
fifty minutes per week and at least four class tests. A two (2) credit course will
involve at least two classes of fifty minutes per week and at least three class tests.
Of the total marks, 70% marks will be from written examination to be held at the
end of the semester and 20% marks from class tests conducted throughout the
course and 10% marks from class attendance.
Candidates having less than 60% attendance will not be allowed to sit for the
examination.
Students having less than 60% attendance in each course of any semester shall be
eligible for readmission once only in the following Session within the admission
schedule notified for regular batch of students of the semester concerned.
Basis for awarding for class partition (10% marks) will be as follows:
Attendance Marks
90% and above 10
85% to less than 90% 9
80% to less than 85% 8
75% to less than 80% 7
70% to less than 75% 6
65% to less than 70% 5
60% to less than 65% 4
Less than 60% 0
Practical Courses: A two (2) credit course will involve four classes of fifty
minutes per week. Out of total marks, 70% marks will be allocated for continuous
assessment, 20% marks will be from one quiz test and 10% marks will be from
viva voce. A one and half (1.5) credit course will involve three classes of fifty
minutes per week. Out of total marks, 70% marks will be allocated for continuous
assessment, 20% marks will be from one quiz test and 10% marks will be from
viva voce.
Practical/Lab/Field trip and Viva-voce Courses:
70% of the Practical/Lab marks shall be awarded on the basis of class
performance during the whole course of study conducted by the course teacher
and the rest 30% on the basis of Quiz-test and viva-voce to be evaluated by 02
(two) examiners suggested by the examination committee in which 01(one)
examiner will be as internal from the concern department and another as external
from the other universities/institutions.
Project Work/Internship/Thesis/Industrial Training Courses:
Seventy percent (70%) of marks shall be awarded on project paper/thesis to be
evaluated by 02 (two) examiners suggested by the examination committee in
which 01 (one) examiner will be as internal from the concern department and
another as external from the other universities/institutions, the rest thirty percent
(30%) on the basis of project/thesis presentation/defense/viva-voce to be
conducted by examination committee preferable in presence of external member.
Page 3 of 72
Distribution of Oral/Viva-voce/Comprehensive Viva-voce courses:
Hundred percent (100%) of marks shall be allotted for oral examination conducted
by the relevant examination committee in presence of one external examiner (may
be the external member of the relevant examination committee) from other
Universities/Institutions.
Grading System:
Letter Grades and corresponding Grade points shall be awarded as follows:
Numerical Grade Letter Grade Grade point
80% and above A+
4.0
75% to less than 80% A 3.75
70% to less than 75% A-
3.50
65% to less than 70% B+
3.25
60% to less than 65% B 3.00
55% to less than 60% B-
2.75
50% to less than 55% C+
2.50
45% to less than 50% C 2.25
40% to less than 45% D 2.00
Less than 40% F No Grade Point
Withdrawn W -
Promotion system:
A student is normally required to earn at least 50% credits in a semester. At the
end of each semester, the students will be classified into the following three
categories:
Category 1: Students who have passed all the courses prescribed for the semester
and have no backlog of courses. A student belonging to category 1 shall be
eligible to register for all courses prescribed for the next semester.
Category 2: Students who have earned at least 50% credits in the semester. A
student belonging to category 2 is advised to take at least one course less in the
next semester subject to the condition that he/she has to register for such backlog
courses as may be prescribed by the department.
Category 3: Consisting of students who have failed to earn 50% credits in the
semester. A student belonging to this category is advised to take at least two
courses less in the next semester subject to registration for a minimum of 50%
credits. However he/she will be required to register for such backlog courses as
may be prescribed by the department.
• If there is any fraction to calculate the minimum 50% credits, the students will be
earned minimum round credits. That is, there is no fraction credit.
• A student of 1st , 2
nd , 3
rd , 4
th , 5
th , 6
th , 7
th , 8
th semester can take a course one
time as backlog course because he/she has to complete the program within 06
(six) academic years.
• A student of category 2 and 3 will not be allowed to take more than 25 credits
(including backlog courses) in any semester.
Page 4 of 72
• In addition to these two regular semesters, there may be a short semester in the
intervening period between end of Semester-2 and commencement of semester-1.
During this short semester students, those who need, may take additional courses
to make up deficiencies in Credit and GPA requirements for bachelor’s degree
spending less than the normal duration; and other students may take vacation.
Degree Requirements:
i) The candidate carrying F Grade in any course shall not be awarded the degree
of B.Sc. Honours.
ii) At least a CGPA of 2.50 must be achieved to get a B.Sc. (Hons.) degree.
Grade Point Average (GPA) Calculation:
No credits are granted for grade less than D. Grade Point Average (GPA) is
calculated as total points secured divided by credit earned. Computation of Grade
Point Average (GPA) and Cumulated Grade Point Average (CGPA).
��� =∑CG
∑CO
Where, C = Credit Hour(s) in a Course
G = Grade point acquired in the corresponding course
CE = Credits Earned (marks obtained ≥40%)
Course Code Credit
Hour(s) (C) Marks (%)
Corresponding
Letter Grade
Grade
Point (G)
Point Secured
(CG)
CHEM 1101 3 68 B+ 3.25 9.75
CHEM 1102 1 72 A- 3.50 3.50
CHEM 1103 3 85 A+ 4.00 12.00
CHEM 1104 1 W -- --
CHEM 1105 3 38 F -- --
CHEM 1106 3 82 A+ 4.00 12.00
CHEM 1107 2 65 B+ 3.25 6.50
CHEM 1108 2 75 A 3.75 7.50
ΣCE = 14 ΣCG = 51.25
�, ��� =51.25
14= 3.66
������������ℎ�� ��� ���, ��� =54.75
17= 3.22
"ℎ������, #��� =51.25 + 54.75
14 + 17= 3.22
Page 5 of 72
The courses to be offered in the different semesters are detailed below:
1st Year 1
st Semester
Course
Code Title of the course Credits Hrs/Week Page
CHEM-1101 Fundamentals of Physical Chemistry 2.0 02 8
CHEM-1102 Physical Chemistry Laboratory-I 1.5 03 9
CHEM-1103 Atomic Structure and Chemical Bonding
(Fundamental Concepts) 2.0 02 9
CHEM-1104 Qualitative Inorganic Analysis –I (Laboratory) 1.5 03 11
CHEM-1105 Fundamentals of Organic Chemistry 2.0 02 11
CHEM-1106 Calculus 3.0 03 12
CHEM-1107 Mechanics and Properties of Matter and Waves 3.0 03 13
CHEM-1108 Biology 2.0 02 14
CHEM-1109 Communicative English 2.0 02 15
CHEM-1110 Oral 0.5 - -
19.5 - -
1st Year 2
nd Semester
Course Code Title of the course Credits Hrs/Week Page
CHEM-1201 Chemical Thermodynamics and Equilibrium 3.0 03 16
CHEM-1202 Physical Chemistry Laboratory -II 1.5 03 17
CHEM-1203 Inorganic Reactions, Solvents and Polymers 2.0 02 17
CHEM-1204 Qualitative Inorganic Analysis –II
(Laboratory) 1.5 03 18
CHEM-1205 Chemistry of Functional Groups 3.0 03 19
CHEM-1206 Organic Chemistry Laboratory -I 1.5 03 20
CHEM-1207 Ordinary and Partial Differential Equation 2.0 02 21
CHEM-1208 Electricity and Magnetism 3.0 03 21
CHEM-1209 Oral 0.5 - -
18 - -
2nd
Year 1st Semester
Course Code Title of the course Credits Hrs/Week Page
CHEM-2101 Phase and Ionic Equilibrium 2.0 02 23
CHEM-2102 Physical Chemistry Laboratory -III 1.5 03 24
CHEM-2103 Chemistry of Elements 3.0 03 24
CHEM-2104 Quantitative Inorganic Analysis (Laboratory) 1.5 03 25
CHEM-2105 Chemistry of Cyclic Compounds and Drugs 3.0 03 26
CHEM-2106 Preparative Organic Chemistry Laboratory 1.5 03 27
CHEM-2107 Computational Chemistry Laboratory 2.0 02 28
CHEM-2108 Mathematical Methods 2.0 03 29
CHEM-2109 Electronics and Optics 2.0 02 29
CHEM-2110 Oral 0.5 - -
19 - -
Page 6 of 72
2nd
Year 2nd
Semester
Course Code Title of the course Credits Hrs/Week Page
CHEM-2201 Electrochemistry 2.0 02 31
CHEM-2202 Electro-analytical Laboratory 1.5 03 32
CHEM-2203 Analytical Chemistry 3.0 03 32
CHEM-2204 Quantitative Inorganic Laboratory -II 1.5 03 33
CHEM-2205 Bioorganic Chemistry 3.0 03 34
CHEM-2206 Polymer Chemistry 2.0 02 35
CHEM-2207 Nuclear and Radiation Chemistry 3.0 03 36
CHEM-2208 Statistics and Numerical Methods 3.0 03 37
CHEM-2209 Oral 0.5 - -
19.5 - -
3rd
Year 1st Semester
Course Code Title of the course Credits Hrs/Week Page
CHEM-3101 Chemical Kinetics and Photochemistry 2.0 02 39
CHEM-3102 Physical Chemistry Laboratory -IV 1.5 03 40
CHEM-3103 Atomic Structure and Chemical Bonding
(Advanced Concept)
2.0 02 40
CHEM-3104 Separation Chemistry 2.0 02 41
CHEM-3105 Chromatographic Separation Laboratory 1.5 03 43
CHEM-3106 Chemical Spectroscopy 3.0 03 43
CHEM-3107 Identification of Organic Compounds
(Laboratory)
1.5 03 45
CHEM-3108 Fundamentals of Pharmaceutical Chemistry 3.0 03 45
CHEM-3109 Pharmaceutical Chemistry Laboratory 2.0 04 47
CHEM-3110 Microbiology 2.0 02 47
CHEM-3111 Oral 0.5 - -
21.0 - -
3rd
Year 2nd
Semester
Course Code Title of the course Credits Hrs/Week Page
CHEM-3201 Colloid and Surface Chemistry 2.0 02 48
CHEM-3202 Transition Metals and Coordination
Chemistry
3.0 03 49
CHEM-3203 Inorganic Synthesis Laboratory 1.5 03 50
CHEM-3204 Supramolecular Chemistry 2.0 02 51
CHEM-3205 Organic Reaction Mechanism 3.0 03 51
CHEM-3206 Stereochemistry 3.0 03 52
CHEM-3207 Industrial Chemistry 3.0 03 54
CHEM-3208 Industrial Chemistry Laboratory and Field
Visit
1.5 + 0.5
= 2.0
04 55
CHEM-3209 Biochemistry 2.0 02 55
CHEM-3210 Oral 0.5 - -
22.0 - -
Page 7 of 72
4th
Year 1st
Semester
Course Code Title of the course Credits Hrs/Week Page
CHEM-4101 Applications of Spectroscopic Methods in
Chemical Analysis
3.0 03 57
CHEM-4102 Biophysical Chemistry 2.0 02 58
CHEM-4103 Chemistry of Solids 2.0 02 59
CHEM-4104 Environmental Chemistry 3.0 03 60
CHEM-4105 Green Chemistry 2.0 02 61
CHEM-4106 Theoretical Organic Chemistry 3.0 03 62
CHEM-4107 Chemistry of Natural Products 2.0 02 63
CHEM-4108 Organo-applied Chemistry Laboratory 1.5 03 64
CHEM-4109 Chemistry Research Methodology 2.0 02 64
CHEM-4110 Oral 0.5 - -
21.0 - -
4th
Year 2nd
Semester
Course Code Title of the course Credits Hrs/Week Page
CHEM-4201 Quantum Chemistry and Statistical
Thermodynamics
3.0 03 66
CHEM-4202 Organometallic Chemistry 3.0 03 67
CHEM-4203 Nanochemistry 2.0 02 68
CHEM-4204 Bioinorganic Chemistry 2.0 02 69
CHEM-4205 Organic Reagents and Syntheses 2.0 02 70
CHEM-4206 Medicinal Chemistry 2.0 02 71
*CHEM-4207 Internship at Industry or Research
Organization/ Project work
6.0 12 -
20.0 - -
• The Project/Internship work must be started from 4th
Year 1st Semester.
Page 8 of 72
Course Code: CHEM 1101
Fundamentals of Physical Chemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Gaseous state: Ideal gases: Boyles law, Charles’ and Gay-Lussac’s law,
Avogadro’s law, Ideal gas equation, Dalton’s law of partial pressure; Real gases: van
der Waals equation, Viral equation of state; Molecular interpretation of ideal and real
gases; Condensation of gases and critical state; Kinetic theory of gases; Maxwell
distribution laws; Molecular collisions and Mean free path; Graham’s laws of
diffusion and effusion.
2. The liquid state: Phase transition and its types: melting, freezing, vaporization,
condensation, sublimation, deposition, vapor pressure, boiling point, melting point.
Properties of liquids: surface tension, viscosity, polarity, dielectric constant, dipole
moment, molar reflectivity. Different intermolecular forces (dipole-dipole, London
(dispersion) forces, van der Waal's), hydrogen bonding, structure and properties of
water.
3. The solid state: Molecular interpretation, Amorphos and crystalline solid, unit cell,
Elementary idea on crystalline system, isomorphism and polymorphism, law of
isomorphism.
4. Fundamental concepts of solution: Definitions: Mixture, Homogenous and
Heterogenous mixtures. Properties of solution. Types of solutions, ways of expression
concentration of solution. Colligative properties, ideal and non-ideal solutions;
vapour-pressure measurement; Raoult’s law, elevation of boiling point, depression of
freezing point, osmotic pressure: its determination, laws of osmotic pressure; reverse
osmosis, thermodynamics of colligative properties; ideality of solutions;
thermodynamic treatment of colligative properties, Henry’s Law. Solute-solvent
interactions: hydrophobic and hydrophilic interactions.
5. Chemical equilibrium and Kinetics: Concept of equilibrium, Equilibrium law and
constant, Le Chatelier and Braun’s principle and its application. Reaction rate, order
and molecularity, Experimental determination of rates, Determination of order and
rate constant, Dependence of rates on concentration and temperature, Rate laws and
mechanism, elementary and complex reactions, Preliminary concepts of collision and
transition state theories.
Books Recommended
1. P. Atkins and J. Paula, Atkins Physical Chemistry, (8th
edition) W. H. Freeman
and Company, New York.
2. Gurdeep. Raj, Advanced Physical Chemistry, Goel Publishing House, 2007.
3. S. H. Maron and C. F. Prutton, Principles of Physical Chemistry, Oxford and IBH
Publishing Co. Pvt. Ltd.
4. D. D. Ebbing, General Chemistry, Houghton Mifflin Company, Boston.
5. Raymond Chang, Chemistry, Tata McGraw-Hill Publishing Company Limited,
New Delhi.
Page 9 of 72
Course Code: CHEM 1102
Physical Chemistry Laboratory-I
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Determination of the formula of a hydrate.
2. Determination of relative atomic mass (i.e. atomic mass) of magnesium.
3. Determination of molecular weight of a volatile substance (condensable vapor) by
Victor Mayer’s method.
4. Determination of the molecular weight of a given liquid by steam distillation
method.
5. Acid-base titration with different indicators.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. Palit, Practical Physical Chemistry, Science Book Agency, Calcutta.
2. Sharma, Practical Physical Chemistry, Vikas Publishing House Pvt. Ltd.
3. J.B. Yadav, Advanced Practical Physical Chemistry.
4. Khalique, A Text Book of Practical Chemistry, Ideal Library, Bangla Bazar,
Dhaka.
5. O.P. Pandey, D.N. Bajpai, and S. Giri, Practical Chemistry, S. Chand & Co. Ltd,
New Delhi.
6. A. Findlay, Longmans, Practical Physical Chemistry, Green and Company Ltd.
Course Code: CHEM 1103
Atomic Structure and Chemical Bonding (Fundamental Concepts)
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Atomic Structure (Quantum Mechanical Approach): Fundamental particles,
Cathode rays, Mass and charge of electrons, Radioactivity, α-particle scattering
experiment (Rutherford atom model), Isotopes, Electromagnetic radiations and
spectrum, Atomic spectra, Photoelectric effect, Bohr’s model of hydrogen atom,
Emission spectrum of the atomic of hydrogen, Planck’s quantum theory, Quantum
numbers, Refinements to Bohr’s atom model, Bohr-Sommerfield model, Atomic
orbitals, Pauli’s exclusion principle, Aufbau Principle, Hund’s rule.
2. Periodicity of the Elements: Periodic law, Modern periodic table and
classification of elements, Electronic configuration using periodic table, Diagonal
relationship, Periodic properties-ionization energy, electron affinity, atomic
radius, electronegativity, ionic radii, metallic character, melting and boiling
points, Usefulness and limitations of periodic table.
3. The Chemical Bonds: Overview, Types of bond, Transition between main types
of bonding, Lewis formula, Octet rule and its exceptions.
Page 10 of 72
(a) Ionic Bond: General description, Energy changes in ionic bond formation,
Limitations to form ions, Fajans’s rule, Partial covalent nature of ionic
compounds, Lattice energy and Born-Haber cycle, Factors influencing formation
of ionic bond.
(b) Covalent Bond: General description, Energy change during bond formation,
Covalency and maximum covalency of an element, Valence bond theory: general
description, sigma (σ) and pi (π) bonds, hybrid orbitals, molecular geometry and
directional bonding-valence shell electron pair repulsion theory; shapes of
different covalent molecules according to VSEPR theory, effect of
electronegativity on bond angle. Resonance; resonance energy, conditions
necessary for resonance, Dipole moment, Non-polar and polar covalent bonds,
Molecular orbital theory: principles of molecular orbital theory, bonding and
antibonding molecular orbitals, their significance and characteristics, stability of
molecules, bond order, MO diagram of simple diatomic molecules.
(c) Coordination bond, Hydrogen bond, van der Waals forces.
4. Inorganic Nomenclature: Prefixes and affixes used in inorganic nomenclature,
Use of enclosing marks, numbers, letters and italic letters, names for cations,
anions, radicals, heteropoly anions, names of acids, salts, salt like compounds and
complex compounds.
5. Bonding in Metals and Alloys: Theory of metals, Valence bond approach, The
band theory of metals, Metallic properties, Solid solution, Super structure and
intermetallic compounds, Nonstoichiometric compounds.
Books Recommended:
1. Raymond Chang Chemistry, McGraw-Hill, Inc., New York.
2. J.D. Lee, Concise Inorganic Chemistry, ELBS with Chapman & Hall, Croatia.
F.A. Cotton, G. Wilkinson and P.L. Gaus, Basic Inorganic Chemistry, Wiley-
India.
3. S. Prakash, G.D. Tuli, S.K. Basu, and R.D. Madan, Advanced Inorganic
Chemistry, Vol. 1& 2, S. Chand & Co. Ltd., New Delhi.
4. G. L. Miessler and D. A. Tarr, Inorganic Chemistry.
5. D. Ebbing, General Chemistry, Houghton Mifflin Company, Boston,
New York.
6. Manas Chandra, Atomic Structure and Chemical Bond including Molecular
Spectroscopy, Tata McGraw-Hill Publishing Co. Ltd.
7. S. Z. Haider, Introduction to Modern Inorganic Chemistry, Edexcel
Publishers,Dhaka.
Page 11 of 72
Course Code: CHEM 1104
Qualitative Inorganic Analysis –I (Laboratory)
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Introducing some common apparatus and reagents
a. Use and technical knowledge of an analytical balance, b) Use of graduated
glassware.
2. Some basic techniques:
a. Preparation of the substance for analysis and weighing the sample.
b. Preparation of the solution of various samples in differing concentration
expression.
3. Systematic qualitative analysis of inorganic substances
a. Physical appearance
b. Preliminary dry test
4. Removal of interfering acids for systematic examination of bases in solution.
5. Analysis of insoluble substances.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. G.H. Jeffery, J. Bassett, J. Mendham and R.C. Denney: Vogel’s Qualititative
Inorganic Analysis, Longman Scientific & Technical, New York.
2. O.P. Pandey, D.N. Bajpai, and S. Giri, Practical Chemistry, S. Chand & Co. Ltd,
New Delhi.
3. E.S. Gilreath, Experimental Procedures in Elementary Qualitative Analysis,
Mcgraw-Hill.
Course Code: CHEM 1105
Fundamentals of Organic Chemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Review and Background: Review and background: Origin of organic chemistry;
The structural theory; Electronic structure of carbon and hybridization; Atomic
orbital, Molecular orbital, Covalent bond, Lewis model of bonding, Octet rule,
Shape of molecules and bond angle, Polar and non-polar molecules, Dipole
moment, Resonance, Inductive effect, Mesomeric effect, Functional groups.
2. Aliphatic Hydrocarbons:
(a) Alkanes: Nomenclature of alkanes, Structure, Structural isomerism in alkanes,
conformations: ethane, butane; sources and preparations; Wurtz reaction and its
importance, Physical and chemical properties, Reactions of alkane, Mechanism of
halogenations, orientation and reactivity, reactivity and selectivity; Free radicals,
cabocations, carbanions and their stability study; Electrophiles and nucleophiles,
Pyrolysis: Cracking, Octane number.
(b) Alkenes: Classification by structure: the family, Nomenclature (E, Z-), cis-
trans isomerism in alkenes and cycloalkanes, conditions of geometrical
isomerism, configuration, Structure and preparation, Physical and chemical
Page 12 of 72
properties, Reactions of the carbon-carbon double bond: electrophilic and free
radical addition, Markovnikov and anti-Markovnikov rule, Synthetic application
of oxidation by O3, KMnO4, peracids, etc., Polymerization of alkene, Analysis of
alkene.
(c) Dienes: Structure, Nomenclature, Preparation, Reactions, Diels-Alder reaction,
Hyperconjugation, Stability of conjugated dienes, Polymerization.
(d) Alkynes: Structure & bonding; Nomenclature, Source and preparations,
Physical and chemical properties, Reaction of alkynes, Acidity of alkynes,
Analysis of alkynes.
3. Aromatic Hydrocarbons & Arenes: Source, structure and resonance of benzene,
The concept of aromaticity, Huckel rule, Nomenclature of benzene derivative,
Distribution and polysubstitution: Orientation, Preparation, Electrophilic
substitution with mechanism: nitration, sulphonation, halogenation, alkylation,
acylation, Addition and oxidation reactions.
4. Alkyl and Aryl Halides: Structure, Nomenclature, Preparation, Physical
properties, Substitution and elimination reactions with mechanism (SN1, SN2, E1
and E2), Grignard reagent, Halocarbons-DDT, Gammexane- their uses and
residual effect in the environment.
Books Recommended:
1. R.T. Morrison & R. N. Boyd, Organic Chemistry; Study Guide to Organic
Chemistry, Prentice Hall.
2. T.W.G. Solomon, Organic Chemistry, John Wiley & Sons.
3. B.S. Bahl and A. Bahl, Advanced Organic Chemistry, S. Chand & Co. Ltd., New
Delhi.
4. I.L. Finar, Organic Chemistry, Vol. 1 & 2, Longmans, Green & Co.
5. A. Streitweiser, C.H. Heathcock and E.M. Kosower, Introduction to Organic
Chemistry, Macmillan Pub. Co.
6. W.H. Brown and C.S. Foote, Organic Chemistry, Saunders College Pub.
7. R.W. Griffin Jr., Modern Organic Chemistry, McGraw Hill.
8. P. Sykes, A Guide Book to Mechanism in Organic Chemistry, Orient Longman.
9. Pine, Organic Chemistry, McGraw Hill.
Course Code: CHEM 1106
Calculus
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Basic Concepts of Set Theory: Functions, Limit, Continuity, Differentiability,
Derivatives, Techniques of differentiation.
2. Application of the Derivatives: Maximum and minimum values, Taylor’s series,
Maclaurin’s series, Exponential and Trigonometric series.
3. Partial Differentiation: Maximum and minimum values of multivariate
functions.
Page 13 of 72
4. Indefinite Integrals: Techniques of integration, Definite integrals, Multiple
integrals, γ- and β functions, Application of integration: areas of plane curves,
volumes and surface areas of solids of revolutions.
Books Recommended:
1. T.M. Apostol, Calculus, Wiley International Edition.
2. E. Steiner, The Chemistry Math Book, Oxford University Press.
3. R. Ellis and D. Gulick, Calculus with Analytic Geometry, HBJ.
Course Code: CHEM 1107
Mechanics and Properties of Matter and Waves
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Vector Analysis: Definition, Vector and scalar quantities, vector addition and
subtraction, Scalar and vector products, Vector and dot product of two vectors,
Triple products, Derivatives of vector, Gradient, divergence and curl of a vector.
2. Conservation of Energy and Linear Momentum: Conservative and non-
conservative forces and systems, Conservation of energy and momentum, Center
of mass, Collision problem.
3. Rotational Motion: Rotational motion, Rotational quantities as vectors,
Rotational variables, Rotation with constant angular acceleration, Relation
between linear and angular kinematics of a particle in circular motion, Torque and
angular momentum, Moment of inertia, Rotational dynamics of a rigid body,
Parallel axis and perpendicular axis theorem, Calculation of moment of inertia,
Combined translational and rotational motion of rigid body.
4. Gravitation: Keplar’s laws, Newton’s law, Gravitational field and gravitational
potential energy, Determination of gravitational constant and acceleration due to
gravity, Gravitational attraction of sphere, Mass and density of the earth, Escape
velocity, Acceleration due to gravity, Compound and Kater’s pendulum, Motion
of planet and satellites.
5. Elasticity: Moduli of elasticity, Poison’s ratios, Relation between elastic
constants and their determination, Cantilever, Flat spiral spring.
6. Surface Tension: Definition, Molecular theory, Surface tension and surface
energy, Adhesive and cohesive forces, Pressure inside a soap bubble, Contact
angle.
7. Fluid Dynamics: Viscosity and coefficient of viscosity, Posseule’s equation,
Determination of the coefficient of viscosity of liquid by Stock’s method,
Bernoulli’s theorem and its applications, Torricelli’s theorem, Venturimeter.
8. Oscillatory Motions: Hook’s law, Simple harmonic motion, Lassajous figures,
Combination of harmonic motions, Damped harmonic motion, Forced oscillation
and resonance.
9. Waves in Elastic Media: Physical description of a wave, Types of waves,
Traveling waves, Equation of a traveling wave, Speed of propagation of waves in
a stretched string, Transmission of energy of a traveling wave, Superposition
principle, Group and phase velocity.
Page 14 of 72
Books Recommended:
1. D. Halliday, R. Resnick and K. Krane: Physics Vol.1, John Wiley.
2. M. Spiegle: Vector Analysis, McGraw-Hill Inc., Singapore.
3. D.S. Mathur: Elements of Properties of Matter, S. Chand & Co.
4. Brij Lal & N. Subrahmanyam: Properties of Matter, S. Chand & Co.
5. F.W. Sears: Mechanics, Wave motion and Heat, Addison-Wesley.
6. U.A. Mofiz: Mechanics, Properties of Matter and Waves.
Course Code: CHEM 1108
Biology
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Biology-The Study of Life: Definition of biology, Molecular organization,
Reproduction, Development, Nature of science, Scientific methods, Evolution
theory, Importance of biological science.
2. The Chemistry of Life: The stuff of life, Energy, Water, The chemical building
block of life.
3. The Cells: The overview of cell structure, Structure of prokaryotes and
eukaryotes, Cell ultra-structure: cell membrane, nucleus, golgi complex,
mitochondria, chloroplasts, ribosome, nuclear pores, DNA and RNA, Comparison
of viral, bacterial, animal and plant cells, Brief ideas about cell metabolism, cell
continuity and cell cycle (division), Blood cell structures human and other
chordate animals.
4. Cell–interaction with the Environment: Lipid foundation of membrane,
Architecture of plasma membrane, Passive transport: diffusion, osmosis, Active
transport: Na-K pump, proton pump.
5. The Structure and Function of Plant Tissue: Organization of Plant, Types of
plant tissue, Types of plant cell, Tissue culture.
6. Animal Behavior: Genetic basis, Development, Adaptive, Social, Sociobiology
and animal behavior.
7. Diversity of Life: Classification of living things, Major groups of
microorganisms: virus, bacteria, fungi, and protozoa- general characteristics,
classification, major groups and their importance in nature, non-cellular and
cellular reproduction, infective diseases and their causes.
Books Recommended:
1. P.H. Raken and G.B. Johnson, Understanding Biology, McGraw-Hill, 1988.
2. S.S. Mader, Biology, McGraw-Hill, 1998.
3. Peter H. Raven, George B. Johnson, Jonathan B. Losos, Susan R. Singer, Biology
(7th
ed.), Tata McGraw-Hill Publishers.
Page 15 of 72
Course Code: CHEM 1109
Communicative English
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Grammar: Clause: structure, function, variation and expansion; The noun in the
clause: number, determiners; The pronoun in the clause: number, case, agreement
and reference; The verb in the clause: form, tense, voice, mood, subject-verb
agreement; The modifiers in the clause: adjective, adverb, infinitive, participles;
The conjunctions and prepositions to suggest different relationships: time, space,
cause, result, purpose, condition, exception, etc.
2. Remedial Grammar: Identifying and correcting errors and weakness.
3. Vocabulary: Clues to the meaning of a word, Position in the clause, prefixes,
suffixes, roots; Synonym and antonym; Revisiting and expanding vocabulary.
4. Listening: Fluency, Lexical resource, Grammatical accuracy and correctness.
5. Speaking: How to ask questions: make requests and give instructions; How to
respond to queries: invitation and statements; How to introduce and thank: express
gratitude, regret or appreciation; How to communicate in particular everyday
situations, How to express different concepts: ability, possibility, futurity,
necessity, obligation, assumption, regularity, continuity, arrangement,
comparison, etc.
6. Reading: Summary completion, Matching headings to paragraphs, Identifying
the writer’s views; Multiple choice, Selecting factors, Table completion, Matching
causes and effects, Sentence completion, Short answer questions.
7. Writing: Spelling, Punctuation, Indenting, Brackets, Abbreviation, Numbers and
fractions, Capitalization, Underlining, Hyphenation etc. Organization of writing-
of sentences in paragraphs in essays and letters, Practical writing: personal and
official correspondence, job application, CV, report writing.
Books Recommended:
1. Thomson and Martinet, Cobuild English Grammer, A Communicative of English,
Leech & Svartvik.
2. M. Swan, Practical English Usage, Oxford University Press.
3. N. Lewis, Word Power Made Easy, The Most Effective Vocabulary Builder in the
English language, W. R. Goyal Pub.
4. A.S. Hornby, Oxford Advanced Learner’s Dictionary, Oxford University Press.
Page 16 of 72
Course Code: CHEM 1201
Chemical Thermodynamics and Equilibrium
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Introduction of Thermodynamics and First Law of Thermodynamics: The
basic concepts: system and surrounding. State and state functions. Equilibrium
states and reversibility. Energy, heat and work. The first law: statement and
formulation. Deviation of expression for expansion work and its application at
different conditions. Heat capacity, Relation between Cp and Cv. Joule-Thomson
effect and inversion temperature.
2. Themochemistry: Law of conservation of energy. Heat of reaction. Exothermic
and Endothermic processes. Enthalpy and standard enthalpy changes (enthalpy of
ionization, enthalpy of neutralization, enthalpy of a reaction, enthalpy of
vaporization, laws of thermochemistry etc.). Measurements of enthalpy changes.
Variation of enthalpy with temperature (Kirchoff's equation). Hess law and its
application. Coupled reactions and converting a non-spontaneous reaction to
spontaneous.
3. Second Law of Thermodynamics: Entropy, entropy and second law, Second law
of thermodynamics: Carnot’s cycle, efficiency of Carnot’s cycle, entropy change
at constant pressure and temperature, entropy and probability, entropy change in
reversible and irreversible process. Free energy: Gibbs and Helmholtz (work
function) free energy, net work/maximum work in Gibbs and Helmholts free
energy, condition of spontaneity, Gibbs-Helmholtz equation; Clapeyron equation,
Clausius-Clapeyron equation; Van’t Hoff reaction isotherm and isochor.
Maxwell’s relations: reversible, irreversible, adiabatic and isothermal process.
4. Third Law of Thermodynamics: Nernst heat theorem: third law of
thermodynamics, absolute entropy, entropy and probability, the statistical
approach to entropy, calculation of entropy for gaseous substance.
5. Application of Thermodynamic Principles: Energy conversion. Efficiencies of
power plants: possibilities and limitation of heat engine. Energy balance in a
closed system. Energy balance in a reacting system. Fuels and combustion.
Adiabatic flame temperature. Ignition. Flash point.
6. Thermodynamics and Chemical Equilibrium: Chemical equilibrium involving
ideal and non-ideal gases. Temperature and pressure dependence of equilibrium
constants. Extent of reaction and reaction Gibbs energy.
Books Recommended
1. S. Glasstone, Thermodynamics for Chemists, Affiliated East-West Pvt. Ltd.
2. Samuel H. Maron, Principles of Physical Chemistry, Oxford and IBH Publishing
Co. Pvt. Ltd.
3. Robert J. Silbey, Physical Chemistry, Wiley
4. Gordon M. Barrow, Physical Chemistry, McGraw-Hill
5. P. Atkins and J. Paula, Atkins Physical Chemistry, (9th
edition) W. H. Freeman
and Company, New York
Page 17 of 72
Course Code: CHEM 1202
Physical Chemistry Laboratory-II
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Partition coefficient of iodine between water and dichloromethane.
2. Partition coefficient of between water and toluene and study of association of
benzoic acid or Study of the adsorption of acetic acid or charcoal and examine the
validity of Freundlich’s adsorption isotherm and Langmuir’s adsorption isotherm.
3. Determination of the integral enthalpy of solution of solids calorimetrically.
4. Determination of enthalpy of solution from solubility measurements.
5. Determination of the solubility product of Ca(OH)2 in H2O and to study the effect
of added CaCl2 on the solubility of Ca(OH)2.
6. Verification of the Hess’s law of constant heat summation
7. Determination of the equilibrium constant for the reaction KI + I2 � KI3.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. M.M. Huque and M.Y.A. Mollah, Principles of Physical Chemistry, Fully Revised
Edition, Brothers’ Publication, Dhaka, January, 2009.
2. Palit, Practical Physical Chemistry, Science Book Agency, Kolkata.
3. Sharma, Practical Physical Chemistry, Vikas Publishing House Pvt. Ltd.
4. J.B. Yadav, Advanced Practical Physical Chemistry, Goel Publishing house,
Meerut.
5. Khalique, A Text Book of Practical Chemistry, Ideal Library, Bangla Bazar,
Dhaka.
6. O.P. Pandey, D.N. Bajpai, and S. Giri, Practical Chemistry, S. Chand & Co. Ltd,
New Delhi.
7. A.J. Mian and M.M. Hoque, Practical Chemistry, Student Publications, Dhaka.
8. A. Findlay, Practical Physical Chemistry, Longmans, Green and Company Ltd.
9. D.T. Burns and E.M. Rattenbury, Introductory Practical Physical Chemistry,
Elsevier.
Course Code: CHEM 1203
Inorganic Reactions, Solvents and Polymers
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Acids and Bases: Modern concepts of acids and bases: Arrhenius concept,
Bronsted-Lowry concept, Lewis concept, Limitations, Conjugate acids and bases,
Classification of Bronsted acid-bases, Acid-base strength, Hard soft acid base
principle (HSAB principle), pH, pOH, Buffer solution and buffer action,
Henderson-Hasselbalch equation, Acid-base indicator, pH curve and indicator
range, choice of suitable indicator, Theories of acid-base indicators.
2. Types of Reactions: Acid-base reactions, double decomposition reactions,
precipitation reactions, substitution reactions, condensation reactions, addition
Page 18 of 72
reactions, elimination reactions, isomerization reactions, polymerization reactions,
oxidation-reduction reactions, Electronic concept of oxidation and reduction,
oxidation state and oxidation numbers, assignment of oxidation numbers,
balancing of redox reactions, oxidation-reduction potentials, oxidizing reducing
agents, Prediction of redox reaction.
3. Solvent Chemistry: Solvent properties; donor and acceptor properties,
Classification of solvents: protic and aprotic solvents, chemistry of some non-
aqueous solvents: properties of ionizing solvents, acid base phenomenon in non-
aqueous systems, Studies of some typical non-aqueous ionizing solvents: liquid
NH3, liq. Sulfur dioxide, hydrogen fluoride, liquid N2O4, BrF3, anhydrous
sulphuric acid, acetic acid, liq. H2S.
4. Electron Deficient and Nonstoichiometric Compounds: (a) Boron hydrides and
their derivatives, properties and studies of their bonding and structures; the
borohydrides, (b) Metal carbides, classification, structure formation and uses,
Graphite compounds.
5. Inorganic Polymers: Chain and network polymers, Silicon polymers, Boron
nitrogen polymers, Sulphur-nitrogen polymers, Phosphonitrilic compounds,
Chemistry of fullerenes.
Books Recommended:
1. F.A. Cotton, G. Wilkinson and P.L. Gaus, Basic Inorganic Chemistry, Wiley-
India.
2. J. Huheey, Keiter & Keiter, Inorganic Chemistry, 5th ed., India.
3. G.L. Miessler & D.A. Tarr, Inorganic Chemistry, 3rd ed., Pearson, India.
4. Raymond Chang, Chemistry, McGraw-Hill, Inc., New York, 1994.
5. T.C. Waddington, Nonaqueous Solvents (Study in Modern Chemistry) Thomas
Nelson & Sons Ltd.
6. S. Prakash, G. D. Tuli, S.K. Basu, and R.D. Madan, Advanced Inorganic
Chemistry, Vol. 1& 2, S. Chand & Co. Ltd., New Delhi.
7. K. Kundu, Oxidation-Reduction and Acid-Base Reactions, Bangla Academy,
Dhaka.
8. S. Z. Haider, Introduction to Modern Inorganic Chemistry, Edexcel Publishers,
Dhaka.
Course Code: CHEM 1204
Qualitative Inorganic Analysis-II (Laboratory)
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Identification of inorganic cations and anions in mixture by semi-micro qualitative
inorganic analysis.
2. Making of models of 7 crystal structures.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Page 19 of 72
Books Recommended:
1. G.H. Jeffery, J. Bassett, J. Mendham and R.C. Denney: Vogel’s Qualitative
Inorganic Analysis, Longman Scientific & Technical, New York.
2. O.P. Pandey, D.N. Bajpai, and S. Giri, Practical Chemistry, S. Chand & Co. Ltd,
New Delhi.
3. E.S. Gilreath, Experimental Procedures in Elementary Qualitative Analysis,
McGraw-Hill.
Course Code: CHEM 1205
Chemistry of Functional Groups
(Full Marks: 20 + 10 + 70 = 100; 3.0 Credits)
1. Hydroxyl Compounds (Alcohols and Phenol): Structure, Nomenclature,
Physical properties (acidity and basicity of alcohols and phenols), Preparation,
Important reactions of alcohols and phenols: substitution, esterification,
oxidations, ring substitution, coupling with diazonium salts, Reimer-Tiemann
reaction, Phenol-formaldehyde resin of phenol, The Pinacol-Pinacolon
rearrangement, etc, Periodic acid oxidation of glycols.
2. Ethers, Sulphide and Epoxides: Structure, Nomenclature, Preparation,
Williamson-ether synthesis, Physical properties, Reactions, Ethers as protecting
groups, Crown ethers.
3. Carbonyl Compounds:
(a) Aldehydes (Aliphatic & aromatic): Structure, Nomenclature, Relative
Reactivity of carbonyl compounds, General methods of preparations, Physical
properties, Reactions of aldehyde: nucleophilic addition to carbonyl compounds,
oxidation and reduction, A simple study of named reaction: Reimer-Tiemann
reaction, Cannizzaro reaction, Aldol condensation reaction, Perkin reaction and
Wittig reaction: mechanism and application.
(b) Ketones (Aliphatic & aromatic): Structure, Nomenclature, General methods
of preparations, Physical properties, Reactions: nucleophilic addition to carbonyl
compounds, oxidation and reduction
4. Carboxylic Acids (Aliphatic & aromatic) & its Derivatives: Nomenclature,
Orbital picture, Hydrogen bonding, Acidity, Resonance effect and inductive effect
on acidity, General methods of preparations and reactions of carboxylic acids:
hydroxy acids, unsaturated acids, keto acids, synthesis using active methylene
compounds, Derivatives of Carboxylic acids (esters, amides, acid halide and
anhydride s), Relative reactivity of carboxylic acid derivatives.
5. Amines (Aliphatic & Aromatic): Nomenclature, Structure and basicity,
Preparations, Physical properties, Separation of amines, Reactions: alkylation,
conversion into amides, oxidation, ring substitution in aromatic amines, Hoffmann
degradation of quaternary ammonium hydroxides, Analysis of amines, Aromatic
Diazonium salts: Preparation and reactions, Synthesis of azo dyes.
Page 20 of 72
6. Nitro and Nitroso Compouds: General properties and resonance of aromatic
nitro-compounds, Synthesis, Reactivity, Reactions of aliphatic and aromatic nitro
and nitroso compounds, Reduction of nitro compounds, TNT, TNB.
7. Color, Dyes and Pigments: Theories of color and color conjugated systems,
Nomenclature, Classification, Raw materials for synthesis of dyes.
Books Recommended:
1. R.T. Morrison & R.N. Boyd, Organic Chemistry; Study Guide to Organic
Chemistry, Prentice Hall.
2. T.W.G. Solomon, Organic Chemistry, John Wiley & Sons.
3. B.S. Bahl and A. Bahl, Advanced Organic Chemistry, S. Chand & Co. Ltd., New
Delhi.
4. I.L. Finar, Organic Chemistry, Vol. 1 & 2, Longmans, Green & Co.
5. A. Streitweiser, C.H. Heathcock and E.M. Kosower, Introduction to Organic
Chemistry, Macmillan Pub. Co.
6. W.H. Brown and C.S. Foote, Organic Chemistry, Saunders College Pub.
7. R.W. Griffin Jr., Modern Organic Chemistry, McGraw Hill.
8. P. Sykes, A Guide Book to Mechanism in Organic Chemistry, Orient Longman.
9. Organic Chemistry, McCurry
Course Code: CHEM 1206
Organic Chemistry Laboratory-I (Fundamentals)
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Introduction to basic laboratory equipment: Glassware and other personal
items, Assembly and precaution in using glassware, Cleaning glassware, heating
and cooling, Laboratory safety instructions.
2. Melting points and boiling points of organic compounds: Discussion on
melting point and boiling point, Determination of melting point of a solid, mixed
melting points and mixed-melting temperature curve from mixed Tm of two
different organic compounds of nearly same Tm and then taking their Tm’s at
different mol%, Identification of typical functional groups in organic compound,
Determination of boiling point of a liquid.
3. Recrystallization: Discussion on crystallization, Crystallization theory,
Purification of benzoic acid or salicylic acid.
4. Drying: Drying technique of some organic compounds.
5. Distillation: Simple distillation, Fractional distillation, Steam distillation.
6. Solvent extraction.
7. Detection: Detection of N, S and halogens in organic compounds.
8. Solubility test and classification of the organic compounds
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. H.D. Durst and G.W. Gokel, Experimental Organic Chemistry, McGraw-Hill
Book Company, New York, 1987.
Page 21 of 72
2. Vogel’s Text Book of Practical Organic Chemistry, ELBS with Longman, 5th
Edition.
3. L.F. Fiesser, K.L. Williamson, Organic Experiment, D.C. Health & Company
Lexington, Massachusetts, Toronto, 4th
Edition.
4. R.L. Shriner, R.C. Fuson and D.Y. Curtin, Systematic Identification of Organic
Compounds, John Wiley Sons, Inc. New York, London, Sydney.
5. A.I. Vogel, Elementary Practical Organic Chemistry (Part 1), Longman.
Course Code: CHEM 1207
Ordinary and Partial Differential Equation
(Full Marks: 20 + 10 + 70 = 100; 2.0 Credits)
Section-A (Ordinary Differential Equation-ODE):
1. Ordinary Differential Equations of First Order and Second Order: General
principles, Elementary standard types, linear equations with constant co-efficients.
Section-B
2. Partial Differential Equation (PDE): Wave equation, Diffusion equation, Laplace
equation, Poisson equation, Schroedinger equation, Method of separation of variables,
Method of Laplace and Fourier transforms, Formation of PDE, Solution system of
PDE, Legendre and Bessel functions, Laguere and Hermite polynomial.
Books Recommended:
1. E. Steiner, The Chemistry Math Book, Oxford University Press.
2. S. Lang, Linear Algebra, Springer.
3. R.R. Stoll, Linear Algebra and Matrix Theory, McGraw-Hill.
4. R. Ellis and D. Gulick, Calculus with Analytical Geometry, HBJ.
5. K. Mohammad, A Text book of Co-ordinate Geometry and Vector Analysis, The
University Press.
6. A.F.M. Rahman & P.K. Bhattacharjee: A Textbook on Co-ordinate Geometry
(two and three dimensions) and Vector Analysis.
Course Code: CHEM 1208
Electricity and Magnetism
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Electric Field: Charge & matter, Coulomb’s law, Electric field and field strength,
Point charge in an electric field, Electric dipole, Electric field due to dipole,
Dipole in an external electric field, Electric flux, Gauss’s law and its applications.
2. Electric Potential: Electric potential and field strength, Potential due to a point
charge, Electric potential energy, Calculation of field strength from electric
potential.
3. Capacitors and Dielectrics: Capacitance-its calculation, Parallel plate capacitors
with dielectrics, Dielectrics and Gauss’s law, Dielectric constant, Energy stored in
an electric field.
Page 22 of 72
4. Current, Electromotive Force and Circuits: Electron theory of conductivity;
Conductor, semiconductor, insulators and superconductors; Current and current
density, Resistance, Resistivity and conductivity, Ohm’s law, Electromotive force,
Potential difference, Kirchhoff’s law and its applications, Single-loop and multi
loop circuits, DC circuits with LR, RC, LC and LCR in series, AC circuits with
LR, RC, LC, and LCR in series, Ammeters, voltmeter, ohmmeter, watt meter,
frequency meter, AC/DC bridge, digital voltmeter.
5. Magnetic Field and Ampere’s Law: Magnetic field and field strength, Magnetic
force on charge and current, Lorenz force, Torque on a current loop, The Hall
effect, Circulating charges, Ampere’s law and magnetic field near straight wire,
Two parallel conductors, Biot-Savart law, Magnetic materials & their properties.
6. Magnetic Induction: Faraday’s law of induction, Lenz’s law, Induction and
electric field, Inductance and its calculation, An IR circuit’s energy and the
magnetic field, Energy density and magnetic field, Self and mutual inductance.
7. Thermoelectricity: Thermal e.m.f; Seeback, Peltier and Thomson Effects;
Thermoelectric thermometer, Thermocouple.
Books Recommended:
1. D. Halliday and R. Resnicks, Fundamentals of Physics, Part II, John Wiley.
2. A.R. Rafiqullah, A.K.Roy & M.S.Huq, Concept of Electricity and Magnetism.
3. A.F. Kip: Fundamentals of Electricity and Magnetism, McGraw-Hill.
4. K.K. Tewari: Electricity and Magnetism with Electronics, S. Chand & Co. Ltd.,
New Delhi.
5. H.D. Young and RA Freedman, University Physics, Pearson.
Page 23 of 72
Course Code: CHEM 2101
Phase and Ionic Equilibrium
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Physical Transformation of Pure Ssubstances and Phase Diagram: Stabilities
of phases. Phase boundaries. Phase rule and its thermodynamic deviation. Phase
component. Degrees of freedom. Triple point. Metastable system. Phase diagram
of water, carbon dioxide, and helium. Phase stability and phase transitions:
thermodynamic criterion of equilibrium. Dependence of stability on conditions.
Location of phase boundaries: Clapeyron and Clausius-Clapeyron equation,
Ehrenfest classification of phase transitions.
2. Two Component and Three Component Systems: Binary liquid systems.
Distillation of liquids mixtures. Konowaloff's rule. Partially miscible liquids.
Upper and lower consolute temperatures. Effect of salts on CST. Sublimation.
Solid-liquid equilibria. Eutectic point. P-C & T-C diagram. Cryohydrate,
quadruple point. Factional distillation. Fractional column. Completely miscible
liquid pairs. Azeotropes, Congruent and Incongruent malting points. Maximum
and Minimum melting points. Cooling curves. Solid-Liquid, Gas-Solid systems.
Dissociation pressure. CaCO3 Equilibrium formation. Three component systems:
Triangular phase diagrams. Partially miscible liquids. Role of added salts.
3. Chemical Equilibrium: Reaction Gibbs energy. Exergonic and endergonic
reactions. Perfect gas Equilibria. Thermodynamic equilibrium constant.
Equilibrium constant from thermal data. The response of Equilibrium to pressured
and temperature. Le Chatelier's principle. van't Hoff equation. Response of
equilibria to pH: acid-base equlibria in water, acid-base titrations, pH curve, use
of equilibria to direct changes in pH, Ellingham's diagram and application for
metal extraction.
4. Ionic Equilibrium: Degree of ionization. Factors affecting degree of ionization.
Ostwald dillution law. Neutralization & Hydrolysis of Salts. Ionic Product of
Water. pH, pH scale. Buffer solutions: classification, mechanism of buffer action
and applications.
Books Recommended
1. P. Atkins and J. Paula, Atkins Physical Chemistry, (9th
edition) W. H.
Freeman and Company, New York.
2. Gurdeep Raj, Advanced Physical Chemistry, Goel Publishing House, 2007
3. Gordon M. Barrow, Physical Chemistry, McGraw-Hill
4. K. K. Sharma and L. L. Sharma, A Textbook of Physical Chemistry, Vikas
Publishing House Pvt. Ltd.
5. Anthony R. West, Solid State Chemistry and its Applications, Wiley
Page 24 of 72
Course Code: CHEM 2102
Physical Chemistry Laboratory-III
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Determination of enthalpy of neutralization of a strong base by a strong acid.
2. Determination of the phase diagram for the phenol-water system.
3. The pH value of a given solution by indicator method (using buffer solution of
known pH).
4. Determination of the liquid-liquid miscibility of partially miscible three liquid
system.
5. Study of molecular mass by measurements of physical properties:
a. Viscosity and density
b. Surface tension
c. Vapor pressure.
6. Determination of the partial molal volume of solutions (alcohol-water system) by
Westphal balance or density bottle (picknometer).
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. Palit, Practical Physical Chemistry, Science Book Agency, Calcutta.
2. Sharma, Practical Physical Chemistry, Vikas Publishing House Pvt. Ltd.
3. J.B. Yadav, Advanced Practical Physical Chemistry, Goel Publishing House.
4. A. Khalique, A Text Book of Practical Chemistry, Ideal Library, Bangla Bazar,
Dhaka.
5. O.P. Pandey, D.N. Bajpai, and S. Giri, Practical Chemistry, S. Chand & Co. Ltd,
New Delhi.
6. A.J. Mian and M.M. Hoque, Practical Chemistry, Student Publications, Dhaka.
7. A. Findlay, Practical Physical Chemistry, Longmans, Green and Company Ltd.
Course Code: CHEM 2103
Chemistry of Elements
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Symmetry and Structure: Molecular Symmetry; symmetry operations and
elements; symmetry point group; assigning of molecules to point groups;
Symmetry of orbitals.
2. Hydrogen and Hydrides (Group 1): Position in the periodic table: abundance
and preparation of hydrogen, properties of molecular hydrogen; ortho and para
hydrogen; hydrides; hydrogen ion, isotopes of hydrogen, hydrogen bonding,
hydrogen as fuel.
3. Alkali and Alkaline Earth Metal (Group 1 and Group 2): Occurrence and
abundance, Electronic structure, Physical properties, Reaction with water, air and
dinitrogen; oxides, hydroxides, peroxides, sulphates, nitrates, halides,
superoxides; hardness of water, biological importance.
Page 25 of 72
4. Chemistry of Boron and Carbon (Group 13 and 14): Occurrence, abundance
and extraction, General properties, Structure and allotropy of the elements,
Reactions of boron, Chemical reactivity of carbon; carbides, oxides, and
carbonates; oxides of silicon, Preparation of the metals as semiconductors,
Allotropic forms.
5. Chemistry of Group 17 (Halogens): Occurrence, abundance and extraction,
General properties, Reactivity, Charge transfer compounds of halogens, oxides,
oxo-acids and their salts, Halides, Interhalogen compounds and pseudohalogen
compounds.
6. Chemistry of Titanium and Vanadium (Group 4 and 5): Occurrence,
abundance and uses, Oxidation states, General property and Reactivity.
7. Chemistry of Iron, Copper and Zinc (Group 8, 11 and 12): Occurrence,
abundance and uses, General property, Reactivity, Biological importance and role.
8. Chemistry of Molybdenum, Cobalt and Nickel (Group 6, 9 and 10):
Occurrence, abundance and uses, General property, Reactivity, Biological
importance and role.
9. Chemistry of Lanthanides and Actinides: General features, Lanthanides and
Actinide contraction, Variable valency of lanthanides, Magnetic and spectral
properties, Separation of lanthanides and actinides, Superactinides.
Books Recommended:
1. J.D. Lee, Concise Inorganic Chemistry, ELBS with Chapman & Hall, Croatia,
1996.
2. F.A. Cotton, G. Wilkinson and P.L. Gaus, Basic Inorganic Chemistry,Wiley-India.
3. F.A. Cotton, G. Wilkinson and C. A. Murillo, M. Bochmann, Advanced Inorganic
Chemistry,Wiley-India.
4. N.N. Greenwood and A. Earnshaw, Chemistry of the Elements, Butterworth-
Heinemann.
5. S. Prakash, G.D. Tuli, S.K. Basu, and R.D. Madan, Advanced Inorganic
Chemistry, Vol. 1& 2, S. Chand & Co. Ltd., New Delhi.
6. K. Kundu, Chemistry of Main Group Elements (in Bangla), Bangla Academy,
Dhaka.
Course Code: CHEM 2104
Quantitative Inorganic Analysis-I (Laboratory)
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Neutralization titrations:
(i) Standardization of NaOH solution against succinic/oxalic acid.
(ii) Standardization of HCl by titration with NaOH (using both methyl orange and
methyl red indicator).
Page 26 of 72
2. Redox titrations:
(i) Determination of ferrous ion using standard KMnO4 solution.
(ii) Determination of ferric ion using standard K2CrO7 solution.
(iii) Determination of ferrous ion by oxidation with standard KMnO4 solution.
(iv) Determination of ferric ion with standard KMnO4 solution.
3. Iodomertic titrations:
(i) Standardization of sodium thiosulphate solution using dichromate solution.
(ii) Determination of copper iodometrically with standard Na2S2O3 solution.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. G.H. Jeffery, J. Bassett, J. Mendham and R.C. Denney: Vogel’s Quantitative
Chemical Analysis, Longman Scientific & Technical, New York.
2. Pandey, D.N. Bajpai, and S. Giri, Practical Chemistry, S. Chand & Co. Ltd, New
Delhi.
3. K. Kundu, Practical Inorganic Chemistry (in Bangla), Bangla Academy.
4. K. Kundu, Practical Inorganic Analysis (in Bangla), Bangla Academy.
Course Code: CHEM 2105
Essential Topics of Organic Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Chemistry of the Compounds Containing C-S, C-N and C-P Bonds: Organo-
Sulfur Compounds: Nomenclature, Physical properties, Preparation and reactions
of thiols, thioethers, thioaldehydes, thioketone, thioacids, sulphonic acids and their
derivatives; Basic Structural feature of organo-phosphorus compounds; Synthesis
and reactions; Organo-nitrogen compounds: structures, shape, physical and
chemical properties of nitriles, thiocyanates, carbamates, and ureas, imines and
oximes, azides and azo compounds.
2. Carbanions:
I. Aldol and Claisen Condensations: Acidity of α hydrogens, Reactions
involving carbanions, Aldol condensation, Crossed aldol condensation, Reaction
related to the aldol condensation, Claisen condensation.
II. Malonic Ester and Acetoacetic Ester Syntheses: Carbanions in organic
synthesis, Malonic ester synthesis of carboxylic acids, Acetoacetic ester synthesis
of ketones, Decarboxylation of β-keto acids and malonic acids, Direct and indirect
alkylation of esters and ketones.
3. Bi-functional Compounds: 1,3-dienes, α, β-unsaturated carbonyl compounds,
Preparation, Electrophilic and nucleophilic addition, Michael addition, Diels-
Alder reaction, Hydoxy ketone, Hydroxy acids.
4. Heterocyclic Compounds: Aromaticity of heterocycles, Sources, Isolation,
Structures and reactions of five membered ring heterocycles: pyrrole, furan, and
Page 27 of 72
thiophene, Structures and reactions of five membered ring heterocycle compounds
containing two hetero atoms: imidazole and pyrimidine, oxazole, isoxazole,
thiazole and isothiazole. Six membered ring heterocycle: pyridine. Heterocyclic
compounds having fused rings: chemistry and structure of indole, benzofuran,
benzothiophene, quinoline and isoquinoline.
5. Alicyclic Compounds: Small and normal-size rings, their formation,
Conformations: cycloalkanes and bicycloalkanes, Bayer strain theory, Heat of
combustion and relative stabilities of the cycloalkanes, Factors affecting stability
of conformation, reactions, cis-trans isomerism in alicyclic system.
6. Polynuclear Aromatic Compounds: Nomenclature, General treatment,
Numbering in the rings and their resonance, Naphthalene, anthracene and
phenanthrene: their sources, structures, syntheses, reactions and derivatives,
chemical behavior of the derivatives.
7. Synthesis of Some Important Organic Drugs:
(a) Sulpha Drugs: Sulphanilamide, Sulphapyridine, Sulphathiazole,
Sulphadiazine, Sulphamezathine, Sulphaguanidine, Prontosil, Chloriamin-T;
(b) Antimalerials: Plasmoquin, Mepacrine;
(c) Fever Sinking Drugs: Paracetamol, Aspirin, Phenacetin;
(d) Barbiturates: Barbituric acid, Uramil, Alurate, Barbital, Phenobarbital;
(e) Sweetening Agents: Saccharin, Dulcin and Aspartame.
Books Recommended:
1. R.T. Morrison & R. N. Boyd, Organic Chemistry; Study Guide to Organic
Chemistry, Prentice Hall.
2. T.W.G. Solomon, Organic Chemistry, John Wiley & Sons.
3. B.S. Bahl and A. Bahl, Advanced Organic Chemistry, S. Chand & Co. Ltd., New
Delhi.
4. I.L. Finar, Organic Chemistry, Vol. 1 & 2, Longmans, Green & Co.
5. A. Streitweiser, C.H. Heathcock and E.M. Kosower, Introduction to Organic
Chemistry, Macmillan Pub. Co.
6. W.H. Brown and C.S. Foote, Organic Chemistry, Saunders College Pub.
7. R.W. Griffin Jr., Modern Organic Chemistry, McGraw Hill.
8. P. Sykes, A Guide Book to Mechanism in Organic Chemistry, Orient Longman.
9. E. Eliel, Stereochemistry of Carbon Compounds, McGraw-Hill.
10. Acheson, An Introduction to Heterocyclic Compounds, Academic Press.
11. M. R. Islam, Modern Stereochemistry, Royal Publication, Dhaka.
Course Code: CHEM 2106
Preparative Organic Chemistry Laboratory
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Preparation of aspirin.
2. Preparation of Methyl orange
3. Preparation of acetanilide: N-acetylation of aniline.
4. Preparation of p-nitroacetanilide: Nitration of acetanilide.
Page 28 of 72
5. Preparation of p-Iodonitrobenzene from p-nitrobenzene
6. Alkaline hydrolysis of aspirin.
7. Acidic hydrolysis of p-nitroacetanilide.
8. Preparation of dibenzalacetone (condensation reaction between benzaldehyde and
acetone).
9. Preparation of cinnamic acid
10. Preparation of benzylidene acetophenone (chalcone)
11. Preparation of adipic acid
12. Oxidation of cyclohexanol to cyclohexanone.
13. Reduction of 3-nitro acetophenone with Sn/HCl.
14. t-Butanol from t-butyl chloride.
15. Butyl acetate from butanol and acetic acid.
16. Cyclohexene from cyclohexanol.
17. Benzoic acid from toluene.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. Louis F. Fieser, L. Kenneth F. Williamson, Organic Experiments, D.C. Health and
Company, Lexington, Massachusetts.
2. H.D. Durst and G.W. Gokel, Experimental Organic Chemistry, McGraw-Hill
Book Company, New York, 1987.
3. Brian S. Furniss, Vogel’s Text Book of Practical Organic Chemistry, ELBS with
Longman, 5th
Edition.
Course Code: CHEM 2107
Computational Chemistry Laboratory
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
Section-A
1. Computer and Information Technology: Basic Concepts; How computer system
works; Types of modern digital computers.
2. Introduction to Windows and MS-DOS: Microsoft word processing in detail.
3. Microsoft office: Word, Excel, Power point, Access, Integrating.
4. An overview of computer language and software.
Section-B
1. Writing chemistry texts involving chemical formulae, Molecular structure,
Drawing using Chem Office: 2D and 3D, ISIS/Draw, ACD/ChemSketch, Jmol.
2. 3D molecular model building software.
3. Potential energy, HOMO, LUMO energy calculation and Energy optimization of
chemical structure by Gaussian Software, Orca etc.
4. Advanced word processing-Tabs, tables, use of the equation editor in chemistry.
5. Use of graphical software: Origin/Sigmaplot etc
6. Graphical interpretation in chemistry (line graphs and scatter plots etc.).
7. Use of Ortep 3.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Page 29 of 72
Book Recommended:
1. K.C. Laudon, Interactive Computing, McGraw-Hill Companies, Inc. New York,
1996.
2. Mahbubur Rahman, Microsoft Office XP, 2003, 2007, Systech Publications
Publication, 38/3 Bangla Bazar, Dhaka.
3. Molecules-3D: 3D molecular model building software for windows, Quick Start
Guide, Version 2.0, Molecular Arts Corporation, USA.
4. Homepages of ISIS/Draw, ACD/ChemSketch and Jmol.
Course Code: CHEM 2108
Mathematical Methods
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Fourier series, Fourier transformation, Fourier integral, Application of Fourier
series.
2. Laplace transformation, inverse Laplace transformation, Application of Laplace
transformation in ordinary and partial differential equation.
3. Line integral, Volume integral, Surface integral, Green’s theorem, Gauss’s
divergence theorem, and Stoke’s theorem.
Books Recommended:
1. E. Steiner, The Chemistry Math Book, Oxford University Press.
2. S. Lang, Introduction to Linear Algebra, Springer.
3. R.R. Stoll, Linear Algebra and Matrix Theory, McGraw-Hill.
4. R.L. Burden and J.D. Faires, Numerical Analysis, Brooks Cole.
Course Code: CHEM 2109
Electronics and Optics
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Fundamental Properties of Electronic Devices: Conduction in solids, Energy
band picture, Doping of semiconductors, Junction diodes, Circuit properties of a
P.N. junction.
2. Power Rectification and Filter circuit: Half wave rectifiers, Full wave bridge
rectifiers, Capacitor filter, L-section filter, Pi-filter, zener diode.
3. Transistors: Basic concept of transistors, Transistor terminals and symbols,
Construction and operation of transistor, Transistor as an amplifier, CB, CE, CC
configuration and their characteristics, Transistor biasing.
4. Nature and Propagation of Light: Properties of light, Wave theory and
Huygen's principles, Theories of light.
5. Interference: Coherent Source, Young's experiment, Bi-prism, Color of thin film,
Superposition of waves, Newton’s rings.
6. Diffraction: Fresnel and Fraunhoffer diffraction, Diffraction through single - slit,
Diffraction grating.
Page 30 of 72
7. Polarization: Polarized and un-polarized light, Plane of polarization, Polarization
by reflection, refraction, absorption & scattering, Elliptic and circular polarization,
Polarimeter.
Books Recommended:
1. V.K. Mehta and Rohit Mehta, Principle of Electronics, S. Chand & Co. Ltd., New
Delhi.
2. B.L. Theraja, Basic Electronics (Solid State), S. Chand & Co. Ltd., New Delhi.
3. F.A. Jenkins and H.E. White, Fundamental of Optics, McGraw-Hill.
4. Brij Lal and N. Subrahmanyam, A Text Book of Optics, S. Chand & Co. Ltd.,
New Delhi.
5. B.K. Mathur, Principles of Optics.
6. D.S. Mathur, Geometrical & Physical Optics.
Page 31 of 72
Course Code: CHEM 2201
Electrochemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Basic concept of electrochemistry: Scope of electrochemistry. Definition of
EMF. Current. Resistance. Ohm's law. Faraday's law. Specific and Molar
conductance. Classification of Conductors. Electrolytes. Non-electrolytes. Strong
and weak electrolytes. Mechanism of electrolysis. Ion conduction mechanism in
solid electrolyte.
2. Electrolytic and Electronic conduction: Measurement of conductance. Molar
conductance determination. Independent Law of ionic migration. Application of
conductance measurements. Debye-Huckel-Onsager equation for strong
electrolytes. Transport number of ions. Concept about activity and activity
coefficient of electrolytes. Theory of strong electrolytes. Debye Huckel limiting
law. Ionic strength. Electrodes: Origin, Kinds, Three electrode electrochemical
system: Working electrodes, Reference electrodes, Counter electrodes.
3. Electrochemical cell and Concentration cell: Electrode potential and emf of a
cell. Cell reaction and derivation of Nernst equation. Measurement of emf of a
cell. Factors affecting electrode potential. Rates of electrode potential. Different
parameters determined by potential measurements (pH, equilibrium constant,
activity coefficient, transport number, oxidation state etc.). Conductometric
titration. Standard oxidation reduction potential. Different types of cell used in
practical purpose (Quinhydrone electrode, Daniel cell and lead storage battery,
hydrogen electrode, standard cell, calomel electrode). Application of galvanic cell:
emf measurements. Feasibility of a reaction. Potentiometric titration. pH titration.
Electro-gravimetry. Rechargeable battery: dry cell & fuel cell, solar cell.
Photoelectrochemical generation of hydrogen from water.
4. Electrode Process: Polarization: concentration polarization, activation
polarization and Ohmic polarization. Polarography and voltammetry.
5. Industrial applications of Electrochemistry: Chloro-alkali industries,
Electrometallurgy, Electrochemical treatment of industrial effluents. Corrosion:
Types of Corrosion, Prevention of Corrosion.
Books Recommended
1. P. Atkins and J. Paula, Atkins Physical Chemistry, (9th
edition) W. H. Freeman
and Company, New York.
2. Samuel Glasstone, An Introduction to Electrochemistry, East-West Press Private
Ltd.
3. Gordon M. Barrow, Physical Chemistry, McGraw-Hill.
4. Gurdeep. Raj, Advanced Physical Chemistry, Goel Publishing House, 2007
5. A.J. Bard, Electrochemical Methods: Fundamentals and Applications, Wiley
6. Paul Monk, Physical Chemistry (Understanding our chemical world), John Wiley
& Sons Ltd.
Page 32 of 72
Course Code: CHEM 2202
Electro-analytical Laboratory
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credit)
1. Measurement of cell constant of a conductance cell and measurement of the
solubility of a sparingly soluble salt by conductometric method.
2. Determination of conductivity of natural water.
3. Determination of the molar conductance at infinite dilution and dissociation
constant of a weak acid.
4. Conductometric titration of: (a) strong acid, (b) weak acid and to draw their
neutralization curves.
5. Potentiometric titration of: (a) strong acid, (b) weak acid and to draw their
neutralization curves.
6. Determination of the half wave potential of the cadmium ion in 1M potassium
chloride solution.
7. Determination of the standard electrode potential of Zinc and Copper.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. J.B. Yadav, Advanced Practical Physical Chemistry, Goel Publishing House.
2. Khalique, A Text Book of Practical Chemistry, Ideal Library, Bangla Bazar,
Dhaka.
3. O.P. Pandey, D.N. Bajpai, and S. Giri, Practical Chemistry, S. Chand & Co. Ltd,
New Delhi.
4. A. Findlay, Practical Physical Chemistry, Longmans, Green and Company Ltd.
Course Code: CHEM 2203
Analytical Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3.0 Credits)
1. Errors, Sampling and Quantitative analysis: Accuracy, Precision, Mean,
Average, Deviation, Mean deviation, Standard deviation, Coefficient of variation,
Reliability of results, Confidence intervals, Comparison of results, Classification
of errors, Source of errors, Minimization of errors, Determination of the accuracy
of methods of quantitative analysis, Significant figures and their computations,
Statistical treatment of analytical data, Sampling procedures, Sample population,
Significance of representative sampling, Working curve, Blank solution,
Standard-addition technique, Curve fitting, Q-test and T-test
2. Gravimetric Analysis: Precipitation method, Requirements of quantitative
separation, Process of precipitation: saturated and supersaturated solution,
nucleation, crystal growth, Condition of precipitation, Completeness of
precipitation, The purity of the precipitate: co-precipitation, occlusion and post-
precipitation, Washing the precipitate, Thermogravimetric method of analysis,
TGA, DTA, DSC, & DTG analysis of a typical sample.
3. Complexometric Titration: Principles, Complexes and formation constants,
Metal titrants, Chelon effect, Titration curve, Types of EDTA titration, Titration
Page 33 of 72
of mixtures, selectivity, masking and demasking agents, Detection of end point:
Metal ion indicators, Dithizone and diethyldithiocarbamate.
4. Atomic Spectrometric Methods: Emission spectroscopy, Flame emission
spectrometry, Plasma emission spectrometry, Distribution between ground and
excited state, Basic principles of atomic absorption spectroscopy and its
application, Internal standard and standard addition calibration.
5. Spectrophotometric and Polarographic Methods: Spectrophotometric methods,
Beer-Lambert law and its application in UV-Vis spectroscopy, Deviations of
Beer-Lambert law, Determination of pH of a solution by colorimetric methods,
Determination of pK value of an indicator by spectroscopic method,
Spectrophotometric titration, Apparatus for Spectrophotometric titration,
Determination of equilibrium constant by spectrophotometry and determination of
Pb & As. Basic of polarographic analysis, Cyclic voltametry (CV).
7. Ion-exchange Methods: Principles, Types, Action of ion exchange resins, Ion-
exchange equilibria, Factors determining the distribution of ions between ion
exchange resins and solution, Ion exchange capacity, The column separation:
experimental techniques, Some widely used resins, Ion exchange in organic and
aqueous-organic solvents, Separation of amino acids, Effect of complexing agent,
Separation of metal ions on anion exchange columns.
Books Recommended:
1. G.D. Christian, Analytical chemistry, John Wiley & Sons.
2. D.A. Skoog & D.M. West, Fundamental of Analytical Chemistry, Saunders
Publishing.
3. Braun, Introduction to chemical analysis, McGraw Hill International.
4. Ewing, Instrumental methods of chemical analysis, McGraw-Hill International.
5. G.H. Jeffery, J. Bassett, J. Mendham and R.C. Denney: Vogel’s Quatitative
Chemical Analysis, Longman Scientific & Technical, New York.
6. Pecsok and Shields, Modern Methods of Chemical Analysis, John Wiley & Sons.
7. F.W. Fifield & D. Kealey, Principles & Practice of Analytical Chemistry, Wiley-
Blackwell.
8. A Braithwaite and F.J. Smith, Chromatographic Methods, Blackie Academic and
Professional.
9. R.M. Verma, Analytical Chemistry, CBS Publishers & Distributors, India.
Course Code: CHEM 2204
Quantitative Inorganic Analysis-II (Laboratory)
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Precipitation titrations:
(i) Determination of concentration of a silver nitrate solution by Mohr’s method.
(ii) Determination of chloride by Volhard’s method.
2. Complexometric titrations using EDTA:
(i) Determination of zinc by direct titration using Eriochrome-Black T as
indicator.
Page 34 of 72
(ii) Determination of nickel by direct titration using murexide as indicator.
(iii)Determination of calcium by substitution titration using Eriochrome-Black T
as indicator.
(iv) Determination of aluminum by back titration using Eriochrome-Black T as
indicator.
3. Gravimetric analysis:
(i) Determination of lead as lead chromate.
(ii) Determination of sulfate as barium sulfate.
(iii) Determination of iron as Fe2O3.
(iv) Quantitative separation and estimation of copper volumetrically and nickel
(II) gravimetrically.
(v) Determination of calcium and magnesium in a mixture.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. G.H. Jeffery, J. Bassett, J. Mendham and R.C. Denney: Vogel’s Quantitative
Chemical Analysis, Longman Scientific & Technical, New York.
2. O.P. Pandey, D.N. Bajpai, and S. Giri, Practical Chemistry, S. Chand & Co. Ltd,
New Delhi.
Course Code: CHEM 2205
Bioorganic Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Carbohydrates: Definition, Classification, Constitution and configuration of
monosaccharides, Ring structure of monosaccharides with their inter-conversion
and conformations, Synthesis of monosaccharides, Action of acids and bases in
reducing sugars, Epimers, Anomers and anomeric configurations, Structure,
Properties and reactions of mono-, di-, tri-saccharides, Polysaccharides:
Definition, Constitution and Classification, Importance of Polysaccharides,
Isolation of Polysaccharides and their purification using different physical and
chemical methods, Structure elucidation of polysaccharides using chemical and
spectroscopic methods, An introduction of some important polysaccharides such
as starch, cellulose, pectin, alginic acid, chitin, chitosan, glycogen, heparin and
darmatan sulphates.
2. Amino acids, Peptides and Proteins: Definition, sources, classification and
importance of amino acids, its buffer action in biological system, Structure,
configuration, preparation and reactions of amino acids, Biosynthesis of amino
acids, Peptides, its occurrence, constituents and geometry, C- and N-terminal
residues of peptides, primary, secondary and tertiary structure of polypeptides,
Proteins, their classifications and functions, Denatured and conjugated proteins.
3. Lipids: Definition, occurrence, classification and function, Composition of fats
and oils, Hydrolysis of fats, Saturated and unsaturated fatty acids,
Phosphoglycerides, Phosphate esters, Phospholipids and cell membranes,
Biosynthesis of lipids.
Page 35 of 72
4. Nucleic Acids: Definition, sources, and importance, Structure of nucleic acids,
Nucleosides and nucleotides, DNA and RNA.
5. Purine: Chemistry of purines, puric acid; purine derivatives and xanthanes bases.
6. Glycoconjugates: A brief introduction of glycoprotein, proteoglycan and
glycolipid.
Books Recommended:
1. R.T. Morrison & R.N. Boyd, Organic Chemistry; Study Guide to Organic
Chemistry, Prentice Hall.
2. T.W.G. Solomon, Organic Chemistry, John Wiley & Sons.
3. I.L. Finar, Organic Chemistry, Vol. 1 & 2, Longmans, Green & Co.
4. A. Streitweiser, C.H. Heathcock and E.M. Kosower, Introduction to Organic
Chemistry, Macmillan Pub. Co.
5. W.H. Brown and C.S. Foote, Organic Chemistry, Saunders College Pub.
6. R.W. Griffin Jr., Modern Organic Chemistry, McGraw Hill.
7. Guthrie and Honeyman, An Introduction to Carbohydrate Chemistry, Oxford
University Press.
8. O.P. Agarwal, Chemistry of Organic Natural Products, Vol-I & II, Goel
Publishing.
Course Code: CHEM 2206
Polymer Chemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Polymer Structure: Historical Development, Basic Concepts and
Definitions,Difference among common chemical compounds, polymers and
macromolecules, Classification of Polymers, Degree of polymerization,
Nomenclature, Chemical bonding and Polymer Structure.
2. Polymerization: Types of polymerization. Mechanism and kinetics of (a) step-
reaction (condensation) polymerization, (b) radical chain (addition)
polymerization and (c) ionic polymerization. Ring-Opening Polymerization
3. Molecular Weight and Size of Polymers: Average molecular weight of polymers,
Distribution of molecular weight, Determination of molecular weight by end
group analysis, Osmotic pressure measurement, Light scattering, Viscosity
measurement, gel permeation chromatography and ultracentrifugation.
4. Rheology and Mechanical Properties of Polymers: Flow behavior of polymers,
Elasticity and Viscoelasticity, Glass transition temperature (Tg): Factors affecting
the glass transition temperatures, mechanical properties of crystalline polymers:
crystallinity, the crystalline melting point (Tm): Factors affecting the crystalline
melting point.
5. Special Polymers:Preparation with Mechanism, Properties and Uses: Phenol-
formaldehyde resins, Melamine formaldehyde resins, Urea-formaldehyde resins,
Page 36 of 72
Epoxy resins, Polyester polyamide, Polyethylene, PVC, Polystyrene,
Chitin/Chitosan, Alginate, Gelatin, Collagen. Polyurea, Polyaniline.
6. Technology:
• Fibers: Introduction, Production, Textile fibers, Natural fibers, Cellulose, Silk,
Wool.
• Rubber: Overview, Processing and application.
• Plastic: Overview, Processing, Thermoset/ Thermoplastic, Polymer Blends.
Books Recommended
1. F. W. Billmeyer, Text book of Polymer Science, Wiley-Interscience.
2. G. Odian, Principles of Polymerization, Wiley.
3. R. J. Young and P. A. Lovell, Introduction to Polymers, Chapman & Hall
4. R. O. Ebewele, Polymer Science and Technology, CRC press, Boca Raton,
New York, 2000
5. V. R. Gowariker, N. V. Viswanathan & J. Sreedhar, Polymer Science, New
age Intrnational (Pvt.), 1996
Course Code: CHEM 2207
Nuclear and Radiation Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Introduction: Basic Concepts of Nuclear, Radiochemistry and Radiation
Chemistry, Definition and scope of nuclear chemistry; Modern ideas in nuclear
science and technology.
2. Atomic Nucleus: Composition, Size, Density, Mass and Energy correlation,
Nuclear binding energy, Stable and unstable nuclei, Factors responsible for the
stability of a nucleus.
3. Modes of Decay: Radioactivity, Laws governing radioactive decay, Half-life and
average life, Successive decay and branching decay, Radioactive equilibrium.
4. Interaction of radiation with Matter: Interactions of charged particles with
matters and energy loss mechanism, Interaction of gamma radiation with matters,
Photoelectric and Compton effects and pair production, Radiolysis of water spur
reaction.
5. Nuclear Reaction: Basic concepts, Transnucleation, Potential barrier, Elastic and
inelastic scattering, Q-value and threshold energy for nuclear reaction, Reaction
cross section, Excitation function, Reaction mechanism at low and high energy.
Radioactive capture, Photonuclear reaction, Reaction mechanism of low and high
energy, Special reaction: Evaporation, Spallation, Fission, Fusion, Fragmentation,
Transfer reaction. The process of nuclear fission, Fission Fragment and their mass
distribution, Fission energy, Fission cross section and thresholds, Fission
Neutrons, Theory of nuclear fission. Basic principle of Nuclear Reactor, The
natural uranium reactor, The four factor formula, The classification of reactors,
Page 37 of 72
Reactor power, Critical size of thermal reactor; The Breeder reactor; Nuclear
waste management; Nature’s nuclear reactor.
6. Radiation Detection: Ionization current measurement, Ionization chamber,
Multificative ion-collection, G.M. counter, Scintillation counter: operation
principles of NaI (T1) Scintillation detector, Proportional counter, Semiconductor
gamma radiation detector-Ge (Li) and Hyperpure Germanium, Health physics
instruments, Radio isotopes and their uses:Production and separation of radio
isotopes, The Szilard – Shalmers reaction, Isotope dilution analysis, Tracer
technique for reaction kinetics and for industrial, agriculture and medical uses.
7. Nuclear and Radiomechanical Analytical Techniques: Neutron activation
analysis, Isotope, isotope dilution analysis, Radiomechanical tracer techniques,
Production of radioisotopes and labeled compounds, Radiation protection.
8. Radiation Protection: External and internal radiation sources, Radiation effects,
Safety recommendation and regulations.
9. Radiation Processing Technology: Curing, Grafting and Crosslinking.
Books Recommended
1. Friedlander, Kennedy and Miller, Introduction to Nuclear and Radiochemistry,
John Wiley & Sons, New York.
2. H.J. Arnikar, Essential of Nuclear Chemistry, Wiley Eastern Limited, New Age
International Limited, 1995.
3. L. Yaffe, Nuclear Chemistry, Volume 1 & 2, Academic Press.
4. B.G. Harvey, Nuclear Chemistry, Prentice-Hall, Inc. Englewood Cliffs, N.J.
Course Code: CHEM 2208
Statistics and Numerical Methods
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
SECTION-A (Statistics):
1. Definition and scope of the study of statistics; Nature of statistical data; Attributes
and variables; Population and sample; Collection and condensation of data;
Frequency distribution; Graphical representation of data.
2. Mean and standard deviation; Variance, Coefficient of variation; Errors;
Distribution of random errors.
3. Correlation and Regression: Bivariate data, Relationship between the variables,
Distribution and use of coefficient of correlation, Correlation and regression
coefficients, Linear correlation, Partial and multiple correlation, Rank correlation
and correlation ratio.
Page 38 of 72
SECTION-B (Numerical Methods):
1. Polynomial interpolation.
2. Numerical integration.
3. Systems of Linear Equations: Gaussian elimination method, the least square
method.
4. Solution of ordinary differential equation by Euler methods, the Runge-Kutta
methods.
Books Recommended:
1. E. Steiner, The Chemistry Math Book, Oxford University Press.
2. S. Lang, Introduction to Linear Algebra, Springer.
3. R.R. Stoll, Linear Algebra and Matrix Theory, McGraw-Hill.
4. R.L. Burden and J.D. Faires, Numerical Analysis, Brooks Cole.
5. M. Nurul Islam, An Introduction to Statistics and Probability, Mollick Brothers.
Page 39 of 72
Course Code: CHEM 3101
Chemical Kinetics and Photochemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Chemical kinetics: Integration of rate equations for model reaction systems: zero,
first and second order reactions. Elementary reaction and molecularity. Parallel,
Consecutive, Successive and Opposing reactions: methods for determination of
order and rate constant. Complex reactions. Kinetics of polymerization reactions.
Steady state and rate determining step. Chain reactions.
2. Theories of reaction rate: Collision theory, Statistical approach to reaction
dynamics. Transition state theory for bimolecular reactions and its application.
Activated complex theory and collision theories for reaction in solution.
Diffusion-controlled reaction. Effect of dielectric constant & pressure on the rate
of reaction in solution. Primary salt effect. Kinetic isotope effect. Unimolecular
reaction: Lindemann-Hinshelwood approach. Steady state approximation method.
3. Mechanism on the basis of kinetic studies: Thermal decomposition of C2H6,
CH3CHO, CH3COCH3, O3, COCl2, hydrogen bromide reaction and calculation of
activation energy. Solid state reaction: Tarnish reaction & Wagner theory.
Thermal decomposition: mechanism, solid-solid reaction, Photographic process.
4. Catalysis: Competitive adsorption and kinetics of surface reactions. Arrhenius and
van't Hoff's intermediate. Enzyme catalysis: Michaelis-Menten mechanism.
Specific and general acid-base catalysis. Heterogenous catalyst: outline,
application, absorption isotherm & rate law.
5. Elements of Photochemistry: Laws of photochemistry. Quantum yield and its
significance. Photolysis. Photosensitization. Photo-oxidation. Photo-reduction.
Photochemistry of molecular O2, anthracene and carbonyl compounds.
Chemiluminescence, Fluorescence, and Phosphorescence. Solar energy and it's
application. Some storage system fuel: hydrogen application. Photovoltaic cell
and photocurrent.
Books Recommended
1. Keith J. Laidler, Chemical Kinetics, Pearson Education.
2. Samuel H. Maron, Principles of Physical Chemistry, Oxford and IBH
Publishing Co. Pvt. Ltd.
3. K.K. Rohatgi-Mukherjee, Fundamentals of Photochemistry, New Age
International Publishers.
4. Robert J. Silbey, Physical Chemistry, Wiley
5. Gurdeep. Raj, Advanced Physical Chemistry, Goel Publishing House, 2007
6. K. K. Sharma and L. L. Sharma, A Textbook of Physical Chemistry, Vikas
Publishing House Pvt. Ltd.
7. Ira N. Levine, Physical Chemistry, McGRAW-Hill Edition.
8. P. Atkins and J. Paula, Atkins Physical Chemistry, (9th
edition) W. H.
Freeman and Company, New York
Page 40 of 72
Course Code: CHEM 3102
Physical Chemistry Laboratory-IV
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Determination of the kinetics of dissolution of magnesium metal in dilute HCl.
2. Determination the rate constant and order of a reaction between acetone and
iodine in presence of mineral acid and a catalyst.
3. Determination of the specific reaction rate of the hydrolysis of an ester by NaOH
solution (conductometric method).
4. Determination of the molecular weight of a substance by cryoscopic method.
5. Determination of the percentage of D-glucose and D-tartaric acid in a given
solution polarimetrically.
6. Spectroscopic analyses:
(a) Determination of the absorption spectrum of a colored substance in solution
and to verify the validity of Beer-Lambert Law,
(b) Determination of the concentration of an unknown solution,
(c) Determination of stability constant of a complex compound.
(d) Preparation of solution, calibration curve and interpretation of UV-Spectra
(e) Instrument preparation, calibration and interpretation of IR-Spectra.
(f) Determination of the concentration of K2Cr2O7 and KMnO4 in a solution or
mixture by spectrophotometric method.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. Palit, Practical Physical Chemistry, Science Book Agency, Calcutta.
2. Sharma, Practical Physical Chemistry, Vikas Publishing House Pvt. Ltd.
3. J.B. Yadav, Advanced Practical Physical Chemistry, Goel Publishing House.
4. A. Findlay, Practical Physical Chemistry, Longmans, Green & Co. Ltd.
5. Khalique, A Text Book of Practical Chemistry, Ideal Library, Bangla Bazar,
Dhaka.
6. O.P. Pandey, D.N. Bajpai, and S. Giri, Practical Chemistry, S. Chand & Co. Ltd,
New Delhi.
7. A.J. Mian and M.M. Hoque, Practical Chemistry, Student Publications, Dhaka.
Course Code: CHEM 3103
Atomic Structure and Chemical Bonding (Advanced Concepts)
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Atomic Structure (Wave Mechanical Approach): de Broglie’s concept of dual
nature of matter: de Broglie wave equation, Experimental verification of wave
nature of electrons, Confirmation of quantization of angular momentum (Bohr’s
theory) by de Broglie’s concept, Heisenberg’s uncertainty principle, Nature of
Page 41 of 72
wave motion, Schrödinger wave equation, Interpretation of the wave function:
eigen value and eigen function, Solution of the wave equation, Schrödinger
equation for hydrogen like atoms, Separation of variables, radial, angular and
probability functions, Representation of symmetry of orbitals, General
implications of quantum theory in chemistry.
2. Critical Studies of Different Bond Types and Theories:
(a) Ionic Bonds: Energetics of ionic bond formation, Inter- atomic distances and
their relationship with the structures of compounds and crystals, Born-Haber
cycle, Mandelung constant, Lattice energy and its significance, Sizes of ions:
ionic radii and ionic structure, Radius ration effect, Packing of ions in crystals.
(b) Covalent Bonds:
(i) Valence Bond Theory (VBT): Sigma (σ), pi (π) and delta (δ) bonding,
Lewis model, octet rule, expanded octet and limitations, Directional
characteristics of covalent bonds: hybridization, shapes and molecules-VSEPR
theory, Resonance, Isolobality. Valence bond treatment of H2 molecule.
(ii) Molecular Orbital Theory (MOT): Construction of molecular orbital by
LCAO method, Overlap criteria of bond formation: bonding, anti-bonding and
nonbonding orbitals, Bond order, MOs representations of homo- and hetero-
diatomic molecules, HOMO and LUMO, MOs of polyatomic molecules with
б- and л-bonding-the ligand group orbital approach, Comparison of VBT with
MOT, Mixing of molecular orbitals and their correlation diagrams.
Books Recommended:
1. J.D. Lee, Concise Inorganic Chemistry, ELBS with Chapman & Hall, Croatia.
2. F.A. Cotton, G. Wilkinson, C. A. Murillo, M. Bochmann, Advanced Inorganic
Chemistry, Wiley-India.
3. S. Prakash, G.D. Tuli, S.K. Basu, and R.D. Madan, Advanced Inorganic
Chemistry, Vol. 1& 2, S. Chand & Co. Ltd., New Delhi.
4. J.E. Huheey, Keiter & Keiter, Inorganic Chemistry, 4th ed., Harper Collin
College Publishers.
5. Manas Chandra, Atomic Structure and Chemical Bond including Molecular
Spectroscopy, Tata McGraw-Hill Publishing Co. Ltd.
6. G.L. Miessler & D.A. Tarr, Inorganic Chemistry, 3rd ed., Pearson, India.
7. Shriver & Atkins, Inorganic Chemistry, 4th ed.,
Oxford University Press,
India.
8. C.E. Housecroft & A.G. Sharpe, Inorganic Chemistry, 3rd ed., Pearson.
Course Code: CHEM 3104
Separation Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Solvent Extraction: Distribution coefficient, Distribution ratio, Factors favoring
solvent extraction, Quantitative treatment of solvent extraction equilibria,
Page 42 of 72
Synergistic extraction, Ion association complexes, Extraction reagents, Solvent
extraction of metals.
2. Chromatographic Methods:
(i) Introduction: Basic principles of chromatography, Classification of
chromatography, Sorption isotherm and chromatographic behavior, Retention
time, Capacity factor, Way of describing the efficiency of chromatographic
methods, Chromatographic band shapes and band broadening, Chromatographic
terms: adsorbent, support, development, elution, sample, etc., Separation
techniques, Selection of chromatographic methods.
(ii) Adsorption chromatography:
A. Liquid-Solid Chromatography (Column chromatography): Principle,
Adsorption column and column packing, Application of sample to the column,
Separation of components of the sample: simple elution, stepwise or fractional
elution, gradient elution, Adsorbents, Particle size of adsorbents, Solvents,
Factors influencing the relative positions of bands or zones on chromatographic
columns, Separation and detection of colorless compounds on adsorption
column, Applications.
B. Liquid-Solid Chromatography (Gel Chromatography): Principle, Practical
parameters of gel columns, Classification of gels, Gel column and column
packing, Samples, Modified gel chromatography, Gel affinity chromatography,
Gel ion exchange chromatography, Applications.
(iii) Partition Chromatography
Liquid-Liquid Chromatography: Principle, Partition column and its
characterization, Solid supports, Partition column and column packing,
Application of sample in the column, Stationary and mobile phase, Elution.
Identification of separated compounds.
(iv) Ion Exchange Chromatography:
General discussion, Synthesis of ion exchange resin, Desirable properties of ion
exchange resin, Particle size of ion exchange resin, Ion exchange equilibria,
Factors influencing the selectivity coefficient of ion exchanger, Ion exchange
column and column packing, Separation technique: elution, Partition
chromatography with liquid ion exchanger, Separation of Organic compounds on
ion exchange columns: salting out chromatography.
(v) Thin Layer Chromatography:
Principle and theory, Preparation of thin layer on plates, Sample preparation,
Developments of TLC plates, Location of compounds on chromatogram,
Detection of compounds of chromatogram, Factors influencing the Rf value,
Reversed phase TLC, HPTLC, Development techniques of HPTLC, Applications.
(vi) Paper Chromatography:
General discussion and theory of paper chromatography, Factors influencing the
Rf value, Chromatographic paper, Sample preparation, Application of sample to
the chromatographic paper, Choice of solvents, Development of paper
chromatogram, Location of compounds on chromatogram, Defects.
Page 43 of 72
(vii) High Performance Liquid Chromatography:
Definition and general discussion, Basic instrumentation: the mobile phase
reservoir, pumps, sample injection, column, column packing, detectors, High
performance partition chromatography, High performance adsorption
chromatography.
Books Recommended:
1. A Braithwaite and F.J. Smith, Chromatographic Methods, Blackie Academic
and Professional.
2. G.D. Christian, Analytical chemistry, John Wiley & Sons.
3. D.A. Skoog & D.M. West, Fundamental of Analytical Chemistry, Saunders
Publishing.
4. Braun, Introduction to chemical analysis, McGraw Hill International.
5. Ewing, Instrumental methods of chemical analysis, McGraw-Hill
International.
6. G.H. Jeffery, J. Bassett, J. Mendham and R.C. Denney: Vogel’s Quatitative
Chemical Analysis, Longman Scientific & Technical, New York.
7. Pecsok and Shields, Modern Methods of Chemical Analysis, John Wiley &
Sons.
8. F.W. Fifield & D. Kealey, Principles & Practice of Analytical Chemistry,
Wiley-Blackwell.
Course Code: CHEM 3105
Chromatographic Separation Laboratory
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Separation of organic compounds by chromatographic methods:
(a) Preparation of thin layer plates.
(b) Separation of mixture of colored and colorless compounds by TLC.
(c) Separation of colored compounds by column chromatography using alumina
and silica-gel as stationary phases.
(d) Identification of free sugars by paper chromatography and detection of the
separated compounds by dipping and spray reagents.
2. Studies of some organic reactions.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. A. I. Vogel, A text book Organic Quantitative Analysis Part II, ELBS.
2. Chromatography: Published by IFS and ICAT
Course Code: CHEM 3106
Chemical Spectroscopy
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Introduction to Spectroscopy: Electromagnetic radiation, Characterization of
Electromagnetic radiation, Quantization of energy, Absorption and emission of
Page 44 of 72
radiation, Regions of spectrum, Representation of spectra, Signal-to-noise ratio,
Resolving power, Width and intensity of spectral transitions.
2. Electronic Absorption (UV-Vis) Spectrometry: Introduction, Spectra of
hydrogen and hydrogen like element, Electronic angular momentum, The Zeeman
effect, Electronic spectra of diatomic molecule, Vibrational coarse structures,
Frank-Condon principle; Dissociation energy and dissociation products,
Rotational fine structure of electronic-vibration transition, Diatomic molecular
energies in different electronic arrangements, Electronic angular momentum,
Electronic spectra and molecular structure, Technique and instrumentation UV-
Vis spectrometry.
3. Microwave (rotational) Spectroscopy: Rotation of molecules and their
classification, Interaction of electromagnetic radiation with rotating molecule,
Rotational energies of simple linear molecules, Rotational energy levels and
selection rules, Rotational spectra and determination of bond length of diatomic
molecules, Rotation of polyatomic molecules, Techniques and instrumentation,
Microwave oven, Stark and isotope effect.
4. Infrared (vibrational) Spectroscopy: Introduction and principle, Vibration in
molecule, Harmonic and inharmonic vibration in diatomic molecules, Vibration-
rotation spectra of diatomic molecules, Breakdown of the Born-Oppenheimer
approximation: interaction of rotations vibrations, Instrumentation, Vibrational
spectra of polyatomic molecules.
5. Raman Spectroscopy: Quantum theory of Raman effect, Classical theory of
Raman effect, Elementary treatment of Raman spectra, Pure rotational spectra and
Vibrational Raman Spectra. Structure determination from Raman and infrared
spectroscopy, Techniques and instrumentation, Polarization of light and Raman
effect.
6. Magnetic Resonance Spectroscopy: Spin and an applied magnetic field, The
energies of nuclei in magnetic fields, The chemical shifts, Pulse techniques in
NMR, Electron spin resonance (ESR) spectroscopy: introduction, the position of
ESR absorption, The G factor, hyperfine splitting, The fine structure of ESR,
Double resonance in ESR, Techniques in ESR spectroscopy.
7. Solid State and Surface Spectroscopy: Principles of important techniques to
investigate surfaces and the solid state (EELS, RAIRS, Raman Spectroscopy,
Inelastic Helium Scattering, PES, AES, XRF and EXAFS etc.).
8. Mössbauer Spectroscopy: Basic Principle and Applications.
Books Recommended:
1. C.N. Banwell and E.M. McCash, Fundamentals of Molecular Spectroscopy, Tata
McGraw-Hill, New Delhi.
2. G.M. Barrow, Introduction to Molecular Spectroscopy.
3. J.M. Hollas, Modern Spectroscopy, Wiley.
4. G. Chatwal and S. Anand, Spectroscopy (Atomic and Molecular).
5. P.S. Sindhu, Molecular Spectroscopy, Tata McGraw-Hill, New Delhi.
6. F.P. Larkins, Introduction to Spectroscopy.
7. R. Chang, Basic Principles of Spectroscopy, McGraw Hill.
8. D.H. Williams and I. Fleming, Spectroscopic Methods in Organic Chemistry, Tata
McGraw-Hill, New Delhi.
9. P.W. Atkins, Physical Chemistry, Oxford University Press.
Page 45 of 72
Course Code: CHEM 3107
Identification of Organic Compounds (Laboratory)
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Physical appearance.
2. Elemental analysis.
3. Solubility test.
4. Functional group analysis: By (a) chemical methods, (b) Spectroscopic methods.
(i) carboxylic acids, (ii) aldehydes and ketones, (iii) alcohols and phenols, (iv)
esters, (v) amines, (vi) amides and substituted amides, (vii) nitro compounds (viii)
nitriles, (ix) unsaturated compounds, (x) hydrocarbons, (xi) halogenated
compounds, (xii) organo sulphur compounds.
5. Literature survey.
6. Determination of physical constants of organic compounds (b.p., m.p. and mixed
m.p. determination).
7. Naming of the identified compounds.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. H.T. Clarke, B. Haynes, E.C. Brick, G.C. Shone, Hand Book of Organic Analysis,
Quantitative and Qualitative, Edward Arnold, 5th
Edition.
2. R.L. Shriner, R.C. Fuson, and D.Y. Curtin, Systematic Identification of Organic
Compounds, John Wiley Sons, Inc, New York, London, Sydney.
3. H.D. Durst and G.W. Gokel, Experimental Organic Chemistry, McGraw-Hill
Book Company, New York, 1987.
4. B.S. Furniss Vogel’s Text Book of Practical Organic Chemistry, ELBS with
Longman, 5th
Edition.
Course Code: CHEM 3108
Fundamentals of Pharmaceutical Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Introduction: Pharmaceutical process: raw material, classification, testing,
procurement, Importance of pharmaceutical chemicals and processing of
pharmaceutical products, equipments.
2. Pharmacopeia: Introduction, BP, USP, EUP, INN.
3. Pharmaceutical Analysis: Principles underlying qualitative and quantitative
pharmaceutical analysis, Significance of qualitative analysis in pharmaceutical
quality assurance and quality control, Theory and Basic concepts of GMP, ISO
9000, ISO 9001, TQM, (a) Titrametric Analysis: Acid base titration in
pharmaceutical analysis, Redox titration: iodometry and iodimetry, Application in
pharmaceutical analysis, (b) Non aqueous titration: principles and application, (c)
Instrumental analysis: UV, IR, HPLC; Application in drug analysis, (e)
Page 46 of 72
Microbiological assay: principle and applications (specific examples), Sterility
and pyrogen Testing.
4. Unit Process and Unit Operation in Pharmaceutical Chemistry: Design,
construction and safety measures of pharmaceutical manufacturing plant;
Principles involved and technique employed in drying, granulation, mixing, and
clarification; Filtration, milling distillation, control of humidity, refrigeration, air
conditioning, piping and stages, GMP and GMT.
5. Pharmaceutics:
(a) Tablet: Definition, formulation and compounding; Wet and dry granulation
methods, Slugging and capping of tablets, Coating of tablets, Disintegration and
Dissolution test for compressed tablets, Essential qualities of good tablets.
(b) Capsule: Materials for production of hard gelatin capsules, Methods of
capsule filling, Importance evaluation of capsules.
(c) Ointments: Definition and classification, Factors affecting skin absorption,
Ointments bases, Preparation of ointments including dermatological preparation.
(d) Parenteral Products: Definition and types of parenteral products, Vehicles
for parenteral products, Cleaning equipments and preparation of parenteral
products including clarification, Filling, sterilization, sealing and capping,
Control requirements for paranteral products, Pyrogen tests, Sterility test, Foreign
particles, Inspection for leakage, Identity, labeling, storage, Administration of
parenteral products.
(e) Emulsions and Aerosols: Definition and classification, Theory of emulsions,
Emulsifications and emulsifying agents, Types of emulsifying agents,
Sedimentation testing, Preparing equipments, Packing and storage, (b) Internal
and External Liquid: Preparations of different types of Syrups, Elixirs,
Compounding of internal and external liquids, Liquids manufacturing; The
hydrophilic and lyophilic system.
Books Recommended:
1. E.W. Martin, Husa’s Pharmaceutical Dispensing, Mack Publishing. Co.
2. A. Burger, Medicinal Chemistry and Drug Discovery, Wiley-Interscience.
3. A.I. Vogel, A Text Book of Practical Organic Chemistry, Prentice Hall.
4. Curtin, Shriner and Fusion, Systematic Organic Analysis, Wiley.
5. B.G. Katzsung, Basic and Clinical pharmacology, 9 th
edition, McGraw-Hill,
New York.
6. L. Lachman, The Theory and Practice of Industrial Pharmacy, 3 rd
Indian
edition. Varghese Publishing House, Bombay.
7. W.O. Foye, Principles of Medicinal Chemistry, 3 rd
edition, Varghese
Publishing House, Bombay.
8. A. White, P. Handler and E. L. Smith, Principles of Biochemistry, McGraw-
Hill.
9. M. Mesbahuddin and M. R. Islam, General Principles of Pharmacology,
Bengal Library, Dhaka.
Page 47 of 72
Course Code: CHEM 3109
Pharmaceutical Chemistry Laboratory
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Analysis of different raw materials and pharmaceutical products, e.g. assay of
ascorbic acid, aspirin, paracetamol and iron in pharmaceutical formulations.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. British Pharmacopoeia, 2017.
2. United State Pharmacopeia 2017.
Course Code: CHEM 3110
Microbiology
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
Introduction of Microbiology:
1. Important genera and group. Nature and function of beneficial and harmful
bacteria.
2. Role of microorganism in biodegradation of organic compounds.
3. Pathogenic and non-pathogenic bacteria, Toxin produced during food poisoning
and outbreak, Sources of pathogenic bacteria for food contamination and
prevention method.
Control of Microorganism:
1. General principle of microbial control, heat treatment, cold treatment,
dehydration, radiation, filtration; Factors important in the control of
microorganisms.
2. Practical uses of sterilization, disaffection and bacteriastasis, commonly used
chemical disinfectants and other anti-microbial agents in food science.
3. Hygene and Sanitation.
4. Basic principles of microbiological treatment: An aspect of waste water treatment.
Books Recommended:
3. G.J. Tortora, B.R. Funke and C.L. Case, Microbiology: An Introduction, 8th
ed.,
Pearson Education Inc., Singapore.
4. M.J. Peiczar Jr., E.C.S. Chan and N.R. Krieg., Microbiology,. 5th
ed, Tata
McGraw-Hill Publishing Co. Ltd., New Delhi, India.
5. G. Bitton, Wastewater Microbiology. Wiley-Liss, Inc., USA.
6. R.A. Herbert and G.A. Codd, Microbes in Extreme Environment, Academic Press
Inc.
Page 48 of 72
Course Code: CHEM 3201
Colloid and Surface Chemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Colloids: General method of preparation. Classification and general properties of
Colloids. Solubility of colloids. Electrokinetic phenomena: Electrical double
layer, Zeta potential, Electro osmosis, Electrophoresis and Electrodialysis.
Properties of gels, Colloidal electrolytes.
2. Association Colloids: micelle: Emulsions: preparation, types, specific properties
and solubility. Microemulsion. Uses of colloids and emulsions. Micelle
formations by surfactants in water, CMC, thermodynamics of micelle formation,
solubilization of solutions of surfactant; thermodynamics of mixed aqueous
micellar systems.
3. Surface phenomena: Sorption: Absorption and Adsorption. Adsorption on solid
surfaces. Techniques for measurements of adsorption on solid from the gas phase.
Different types of adsorption isotherms for gas-solid system: Freundlich,
Langmuir & BET isotherms. Effect of temperature on adsorption.
4. Chemistry of Interface: Thermodynamic description of interface. Interfacial
tension at a plane surface. Gibb's adsorption equation. Determination of surface
excess concentration. Electrocapillary phenomenon. Surface films: Self-assembled
monolayer. Single layer and Multilayer films. Langmuir film, Langmuir-Blodgett
films, Layer-by-Layer (LbL) films: their preparation and characterization.
5. Introduction of surface characterization tools: Atomic Force Microscopy
(AFM), X-ray photoelectron Spectroscopy (XPS), Scanning Electron Microscope
(SEM), Scanning Tunneling Microscope (STEM), Energy-dispersive X-ray
spectroscopy (EDS, EDX, or XEDS), X-ray reflectivity (XRR), Near edge X-ray
absorption fine structure spectroscopy (NEXAFS), X-ray fluorescence (XRF).
Books Recommended
1. Samuel H. Maron, Principles of Physical Chemistry, Oxford and IBH
Publishing Co. Pvt. Ltd.
2. Arthur W. Adamson, Physical Chemistry of Surfaces, John Wiley & Sons. Inc.
3. A. R. Verma, Crystallography Applied to Solid State Physics, New Age
International Publishers.
4. Gurdeep. Raj, Advanced Physical Chemistry, Goel Publishing House, 2007
5. Richard J. Farn, Chemistry and Technology of Surfactants, Blackwell
Publishing.
6. K. K. Sharma, A Textbook of Physical Chemistry
7. Paul Monk, Physical Chemistry (Understanding our chemical world), John
Wiley & Sons Ltd.
8. M. Satake, Y. Hayashi, Y. Mido, S. A. Iqbal and M. S. Sethi, Colloidal and
Surface Chemistry.
Page 49 of 72
Course Code: CHEM 3202
Transition Metals and Coordination Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Transition Elements: General characteristics, Shape and function of d-orbitals,
Magnetism in transition metal chemistry: origin of paramagnetism, diamagnetism,
Ferromagnetism and antiferromagnetism, Magnetic susceptibility, Curie law.
2. Elements of Coordination Chemistry: Definition and scope of coordination
chemistry, Coordination compounds, ligands and their types, coordination
number; Classification of coordination compounds, Nomenclature of coordination
compounds, Theories of complex compounds: Bolmstrand and Jorgensen’s chain
theory, Werner’s theory, Sidgwick’s electronic interpretation: EAN of metals,
Pauling’s valence bond theory and its limitations, Isomerism stereochemistry of 4-
and 6-coordinated complexes, Chelate complexes, Stabilization of unusual
oxidation states by complexation, Application of coordination compounds.
3. Concepts of Modern Bonding in Coordination Compounds: The crystal field
theory and ligand field theory for octahedral and tetrahedral complexes, Crystal
field stabilization energy, Effects of crystal field splitting, Consequences of ligand
field splitting: magnetic properties, electronic properties, spectrochemical series,
Structural and thermodynamic effect of ligand field splitting, d-d transition, C-T
transition. Tetragonal distortion of octahedral complexes: Jahn-Teller distortion,
Square planner complexes, Tetrahedral complexes, Molecular orbital theory.
4. Stability of complexes: Factors influencing the stability of complexes, Stability
constant, Effect of ligand on the stability of complexes, Measurement of Stability
constant.
5. Reaction Mechanism of Coordination Complexes: Inert and labile complexes,
(i) Ligand substitution reactions: substitution in square-planar complexes, the
trans effect, its application and mechanism, substitution in octahedral complexes,
(ii) Redox reaction: inner-sphere and outer-sphere mechanism.
6. Complexes of π-acid Ligand: Structure, preparation, bonding and properties of
metal carbonyls, phosphine and phosphorus trihalides, π-acid complexes of
nitrogen, metal nitrosyls, π-acid complexes of unsaturated hydrocarbons, π-allyl
and π-aromatic complexes.
Books Recommended:
1. F.A. Cotton, G. Wilkinson and P.L. Gaus, Basic Inorganic Chemistry, Wiley-
India.
2. F.A. Cotton, G. Wilkinson and C. A. Murillo, M. Bochmann, Advanced Inorganic
Chemistry, Wiley-India.
3. S. Prakash, G.D. Tuli, S.K. Basu, and R.D. Madan, Advanced Inorganic
Chemistry, Vol. 2, S. Chand & Co. Ltd., New Delhi.
4. J. Huheey, Keiter & Keiter, Inorganic Chemistry: Principles of Structure and
Reactivity, 4th ed., Prentice Hall, India.
5. G.L. Miessler & D.A. Tarr, Inorganic Chemistry, 3rd ed., Pearson, India.
6. Shriver & Atkins, Inorganic Chemistry, 4th ed.,
Oxford University Press, India.
Page 50 of 72
7. C.E. Housecroft & A.G. Sharpe, Inorganic Chemistry, 3rd ed., Pearson.
8. K. Kundu, Coordination Chemistry, Bangla Academy, Dhaka (Language of the
book is in Bengali).
Course Code: CHEM 3203
Inorganic Syntheses Laboratory
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Preparation of sodium thiosulphate.
2. Preparation of ammonium nickel(II) sulphate.
3. Preparation of tris(thiourea)copper (I) sulfate.
4. Preparation of cis- and trans-potassium dioxalatodiaquachromate(III).
5. Preparation of tris(acetylacetonato)manganese(III) and comparison of its IR
spectra with that of the ligand.
6. Preparation of Al3+
and Cu2+
complexes with acetylacetone and comparison by IR
spectra.
7. Synthesis of NaCl crystals by common ion effect and investigating the crystals by
X-ray diffraction. Determination of the percentage of sodium by ion exchange
method.
8. Preparation of FeSO4. 7H2O. Comparing its masses in an ordinary and Gouy
balance. Quantitative estimation of the components including the moisture content
and the presence of Fe3+
ion as impurity.
9. Preparation of CuSO4.5H2O starting from copper and investigating its infrared
spectrum and thermal dehydration pattern. Interpreting the reactivity of copper
and iron towards sulfuric acids.
10. Synthesis of [Cu(NH3)4]SO4.H2O from CuSO4.5H2O
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. Zvi Szfran, Ronald M. Pike, and Mono M S, Microscale Inorganic Chemistry,
John Wiley & Sons, New York.
2. Gilbert, Alyea, Dutton, and Dersisbach, Tested Demonstration in Chemistry 1-2,
Division of Chemical Education, American Chemical Society.
3 G.H. Jeffery, J. Bassett, J. Mendham, and R.C. Denny, Vogel’s Textbook of
Quantitative Chemical Analysis, Longman and ELBS.
4. G. Pass and H. Sutcliffe, Practical Inorganic Chemistry, Preparations, Reactions
and Instrumental Methods, Chapman and Hall, New York.
5. J.D. Woollins, Inorganic Experiments, VCH Verlagsgesellschaft mbh, Weinheim.
6. K. Kundu, Practical Inorganic Chemistry, Bangla Academy, Dhaka.
Page 51 of 72
Course Code: CHEM 3204
Supramolecular Chemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Conceptual Foundation of Supramolecular Chemistry: Natural and Artificial
Molecular Recognition.
2. Synthesis and Design of Organic and Inorganic Supramolecular Frame-
work: Cryptands and Macromolecules: Catenanes, Rotaxanes, Cubanes,
Peddlanes, Propellanes, Mobius stripes, Trafail knocks, Cage compounds, etc.
3. Host-Guest Interactions: Calthrate Inclusions.
4. Bio-Inorganic Chemistry: Template synthesis, Metal ion and macro molecular
recognition.
5. Molecules and Crystals: Bio-Organic Molecules, Liquid Crystals.
6. Enzymes and Drugs: Recognition behavior of enzymes, Synthetic enzymes.
Drug design and recognition.
7. Surfactants and Micelles: Surfactants, Micelles, Vesicles; Pre-organization of
Interface Active compounds; Self organization.
8. Some Inorganic Supramolecular Systems: (a) Silicates, (b) Molybdenum and
Vanadium Phosphates, (c) Clays, (d) Inorganic Host-Guest Chemistry, Nano-
structures.
Books Recommended:
1. F. Vogtle, Supramolecular Chemistry, John Wiley and Sons.
2. J.M. Lehn, Nobel Lectures of Chemistry, 1980-90.
3. J.M. Lehn, Supramolecular Chemistry: Concepts and Perspectives, Wiley-VCH,
Weinheim.
4. A. Müller, A. Dress and F. Vögtle (ed.): From Simplicity to Complexity in
Chemistry and Beyond, Vieweg, Wiesbaden.
5. Muller, Reuter and Dillinger, Supramolecular Chemistry: Small Guest in Small
and Large Hosts, Angew. Chem. Int. Ed. Eng., 1995, 34, 2328.
6. R.W. Hay, Bio-inorganic Chemistry, Ellis Horwood Ltd., Halsted Press, New
York.
7. Stereochemistry – Eliel & Samuels.
Course Code: CHEM 3205
Organic Reaction Mechanism
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Methods of Determining Reaction Mechanisms: Classes of organic reaction
mechanisms, Methods of determining reaction mechanisms: Meaning of reaction
mechanism, Energy profile, Identification of products, Possible intermediates and
Page 52 of 72
their trapping, Isotopic labelling, Stereochemical studies, Detection of
intermediates; Kinetic study and stereochemical evidence.
2. Substitution Reactions: Nucleophilic substitution reaction in aliphatic system,
Aromatic SN1, nucleophilic substitution in aromatic system (i.e. benzyne), SN2,
SNi etc. Duality of mechanism, SN1 and SN2 reaction mechanism, Factors
affecting the mechanism of substitution reaction, Aromatic substitution both
nucleophilic and electrophilic, Stereochemistry of neighboring group
participation.
3. Addition Reactions: Mechanism of addition to >C = C<, >C = O bonds:
conjugated system like conjugative diene and conjugated unsaturated carbonyl
compounds, their stereochemistry, Kinetics, Hydration of olefins, Addition of
hydrogen halides, Peroxide initiated addition of hydrogen bromide, Addition of
halogens, Diels-Alder reaction, Grignard reagents, Cannizzaro reaction.
4. Elimination Reactions: Comparison of Elimination with addition and
substitution; E1, E2 and E1cB mechanisms, Orientation in elimination reactions,
cis & trans hydroxylation of olefines, cis-hydrogenation, hydrogenation in
presence of dissolved catalyst. Competition between elimination and substitution,
Intramolecular (cis) elimination, Factors affecting the elimination reaction.
5. Polymerization Reactions: Free radical, Cationic and anionic polymerization
reactions, Addition and condensation polymerizations, Epoxy resins formation.
6. Mechanism of Some Important Reactions: Wolf-Kishner reduction,
Clemmensen reduction, Meerwein-Ponndorf-Verley reduction, Oppenauer
oxidation, Reimer- Tiemann reaction. Kneovengel reaction. Aldol Condensations,
Perkin reaction. Benzoin condensation, Baeyer Villiger Oxidation, Wittig
reaction, Michael and Mannich reactions with all mechanistic details, Reduction
with metal hydrides: LiAlH4, NaBH4.
Books Recommended:
1. Peter Sykes, A Guidebook to Mechanism in Organic Chemistry, Orient Longman.
2. Breslow, Organic Reaction Mechanism, Benjamin/Cummings Co.
3. Jerry March, Advanced Organic Chemistry, Reactions, Mechanisms and
Structures, McGraw-Hill.
4. T.H. Lowry and K. S. Richardson, Mechanism and Theory in Organic Chemistry,
Harper Collins Publishers, Inc., New York.
5. C.K. Ingold, Structure and Mechanism in Organic Chemistry, Bell.
Course Code: CHEM 3206
Stereochemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Stereoisomerism: Geometrical isomerism- explanations, interconversion,
geometrical isomerism of polyenes, carbon-nitrogen, nitrogen-nitrogen double
bonds and cyclic aliphatic compounds, Syn-anti nomenclature, physical properties
of geometrical isomers; optical isomerism- optical isomerism due to asymmetric
Page 53 of 72
carbon atoms, optical activity, specific rotations, enantiomerism,
diastereoisomerism, recemic mixture, resolution of racemic mixture, meso
compounds; R & S configurations, absolute and relative configuration and their
correlation.
2. Optical Activity and Optical Isomerism: Cause of optical activity, Chirality,
molecular dissymmetry, Elements of symmetry, Prochirality, Pseudo Chirality,
Racemic modification: nature, formation, properties and their resolutions,
Chirality in molecules devoid of chiral centres: Atropisomerism, biphenyls,
allenes, spirans, annulenes and their R-S configuration; Asymmetric synthesis.
3. Stereochemistry of Fused Ring System: Stereochemistry of decalines,
Perhydroanthrancene, Perhydrophenanthrene, their optical activity and their
relative stability, Fused rings and bridged-ring systems; Bredt’s rule and its
exceptions in flexible ring systems.
4. Conformations: Conformation and conformers, ethanediol, dihydroxystyrene,
dichlorostyrene, their physical properties and stability.
5. Conformational Analysis: Conformation and their physical properties,
Conformational effects on stability and reactivity in diastereoisomers and in
individual compounds, Conformational effects in small, medium and large ring
systems.
6. Optical Rotation and Rotatory Power: Factors leading to chirality, Molecular
dissymmetry, Atomic dissymmetry and conformational asymmetry, Circular
bifringence and circular dichroism (CD), Cotton effect, Octant rule, Dependence
of optical rotation on wavelength-optical rotatory dispersion (ORD).
7. Chiral and Prochiral Molecules: Pro-R, Pro-S, Homotopic and Heterotopic
ligands and faces, Enantiotropic ligands (HCN addition), Diastereotropic ligands
and faces, Enzymatic oxidation-reduction, Prostereoisomerism in biochemical
reactions (citric acid cycle), Stereochemistry of molecule synthesize reaction.
8. Configuration and conformation of cyclic compounds: Three, four, six-
membered ring conformation analysis and di- and poly-substituted cyclohexanes,
Curtin-Hammet Principle.
Books Recommended:
1. R.T. Morrison & R.N. Boyd, Organic Chemistry; Study Guide to Organic
Chemistry, Prentice Hall.
2. T.W.G. Solomon, Organic Chemistry, John Wiley & Sons.
3. B.S. Bahl and A. Bahl, Advanced Organic Chemistry, S. Chand & Co. Ltd., New
Delhi.
4. I.L. Finar, Organic Chemistry, Vol. 2, Longmans, Green & Co.
5. A. Streitweiser, C.H. Heathcock and E.M. Kosower, Introduction to Organic
Chemistry, Macmillan Pub. Co.
6. W.H. Brown and C.S. Foote, Organic Chemistry, Saunders College Pub.
7. R.W. Griffin Jr., Modern Organic Chemistry, McGraw Hill.
8. E.L. Eliel: Stereochemistry of Carbon Compounds, Tata McGraw-Hill
Page 54 of 72
9. Mislow, Introduction to Stereochemistry, Benjamin.
10. P.S. Kalsi, Stereochemistry, Conformation and Mechanism, Wiley Eastern Ltd.
11. E.L. Eliel: Stereochemistry of Carbon Compounds, Tata McGraw-Hill.
12. M. R. Islam, Modern Stereochemistry, Royal publication, Dhaka.
Course Code: CHEM 3207
Industrial Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Fertilizer Industries: Definition, Plant nutrients and their functions, Role of
fertilizer in agriculture, Manufacture of ammonium nitrate, calcium phosphate,
ammonium phosphate, normal super phosphate (NSP), triple super phosphate
(TSP), potassium compounds, Manufacture of urea from natural gas, mixed
fertilizer, Fertilizer industries in Bangladesh.
2. Sugar and Fermentation Industries: Manufacture of cane sugar, Refining of
raw sugar, Production of sugar from sugar Beet, Milling operation and control of
evaporation, Vacuum pen and centrifugal, Seeding or graining, Utilization of by
products, Sugar industry in Bangladesh.
3. Glass and Ceramic Industry: Definition, Types of ceramic products, Basic raw
materials, White wares, Manufactures of porcelain, Chemical conversion
including basic ceramic industry, Heavy clay products, Manufacture of refractory,
enamels, Ceramic industries in Bangladesh, Definition of glass, Classification of
glass, Physical and Chemical properties of glass, Raw materials, Manufacturing
methods of glass, Some special glass and their properties, Refractory’s. Heavy
clay product.
4. Cement Industry: Raw materials, Portland cement manufacture, Types of
Portland cement, Theory of setting and hardening of cement, Different types of
cement, Characteristic of good cement, Testing of cement, Cement factory in
Bangladesh,
5. Pulp, Paper and Rayon Industries: Natural source of cellulose, Different
process for the manufacture of pulp, Recovery of chemicals from waste cooking
liquor, Manufacture of paper board, rayon, cellulose acetate and cellulose nitrate,
Pulp and paper industries in Bangladesh.
6. Paints and Varnishes: Constituents of paints, varnishes, lacquers and enamels
and their functions, Factors influencing satisfactory performance of surface
coating, Properties of pigments, Manufacture of paints and varnish, Difference
between paints and varnishes.
7. Soaps and Detergents: Raw materials, Fat splitting, Manufacturing of laundry
and toilet soaps, Recovery and refining of glycerin, Composition of different types
of soaps. Detergents: definition, classification and their manufacture, Builders,
Additives, Biodegradability of detergents, Comparison of soap and detergents,
cleaning action of soap and detergent.
8. Petroleum Industry: Definition, origin, composition and classification, Refining
and distillation of petroleum, Cracking of petroleum, Motor and aviation fuels,
Natural gasoline, Aviation gasoline, Octane number, Cetane number, Production
of high octane, Alkylation, Polymerization, Isomerization and reforming.
Page 55 of 72
9. Industrial Management: Testing and Quality control, Industrial Management and
Entrepreneurship Development, Environmental & Pollution in industries.
Books Recommended:
1. R.N. Shreve, The Chemical Process Industries, Mc-Graw Hill. International Book
Company.
2. B.K. Sharma, Industrial Chemistry- Including Chemical Engineering, Goel
Publishing House, Meerut.
3. E.R. Riegel, Industrial Chemistry, Reinhold Publishing Co.
4. O.P. Aggarwal, Engineering Chemistry, Khanna Publishers, Nai Sarak, Delhi.
5. G. Martin, Industrial and Manufacturing Chemistry, Vol. I & II.
6. B.N Chokraborty, Industrial Chemistry, Oxford and IBH Publishing Co. (P) Ltd.
New Delhi.
7. A.S.M.N.H. Bhyiyan, Industrial Chemistry and Chemical Technology, Dhaka
University Press.
8. A.R. Bailey, A Textbook of Metallurgy, MacMillan & Co.
9. R.K. Das, Industrial Chemistry (Part I & II), Kalyani. Publishers, New Delhi.
Course Code: CHEM 3208
Industrial Chemistry Laboratory and Field Visit
(Full Marks: 20 + 10 + 70 = 100; 1.5 + 0.5 = 2 Credits)
1. Analysis of different raw materials and products.
2. Industrial tour and submission of tour report.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Books Recommended:
1. E.R. Riegel and J.A. Kent, Riegels’ Handbook of Industrial Chemistry, Kluwer
Academic / Plenum Publishers.
2. Liegue, Engineering Materials.
3. G. Martins, Industrial and Manufacturing Chemistry (Vol. I, II & III).
4. R.K. Das, Industrial Chemistry (Part I & II), Kalyani. Publishers, New Delhi.
5. Kirk-Othmer Encyclopedia of Chemical Technology, John Wiley & Sons.
Course Code: CHEM 3209
Biochemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Biochemical Aspects of Enzymes: Characterization and classification, Coenzyme
and prosthetic group, Brief treatment on enzymatic reaction mechanism and its
regulation, Enzyme inhibition and regulation.
2. Digestive system, digestion and absorption of food.
Page 56 of 72
3. Vitamins: Physiological action and sources of Vitamin A, D, K and thiamine,
riboflavin, niacin, pantothenic acid, cyanocobalamine, folic acid and ascorbic
acid.
4. Metabolism:
(a) Carbohydrate: Glycolytic pathway, TCA Cycle.
(b) Biological oxidation-reduction: Electron transport chain and oxidative
phosphorylation.
(c) Lipid: Beta oxidation, biosynthesis of fatty acid and cholesterol.
(d) Protein: Transamination, deamination, decarboxylation; urea cycle; Protein
biosynthesis, different types of RNA, simple treatment of protein biosynthesis,
genetic code.
5. Hormones: Effects of insulin, thyroxine and glucocorticoids on cellular
metabolism.
Books Recommended:
1. D.L. Nelson & M.M. Cox, Lehninger Principles of Biochemistry, W. H. Freeman,
New York.
2. J.M. Berg, J.L. Tymoczko and L. Styer, Biochemistry, W. H. Freeman, New
York.
3. E.E. Conn and P.K. Stumps, Outlines of Biochemistry, John Willey & Sons.
4. J.L. Howland, Cell physiology, Macmillan, New York.
5. R.K. Murray, D.K. Granner, P.A. Mayes and V.W. Rodwell, Harper’s Illustrated
Biochemistry, McGraw-Hill.
6. US Environmental Protection Agency, Green Chemistry Expert System.
http://www.epa.gov/ oppt/ greenchemistry/ pubs/ gcesdownload.html (accessed
February 2009).
Page 57 of 72
Course Code: CHEM 4101
Applications of Spectroscopic Methods in Chemical Analysis
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Ultraviolet (UV) and Visible (Vis) Spectroscopy: Shifts of bands with solvents,
The isolated double bond, conjugated double bond, conjugated dienes,
Woodward-Fieser rules for calculating λ max, Splitting of electronic energy
levels and spectroscopic states, spectra of d1 , d
2 , d
5 , d
8 and d
9 complexes,
Charge transfer spectra (CT), Calculation of formation constant by UV-vis
spectroscopy.
2. Infrared (IR) and Raman Spectroscopy: FT-IR, Application of IR
spectroscopy, Interpretation of IR spectra, Characterization of functional groups
and frequency shifts associated with structural changes-Structure elucidation,
Raman spectroscopy and its application, Combined IR-Raman spectroscopic
studies for structural determination.
3. Nuclear Magnetic Resonance Spectroscopy: Nuclear spin, Common nuclei with
spin (1H,
13C,
15N,
19F,
31P), Chemical Shift, Theory of PMR spectroscopy,
Shielding and deshielding, Spin-spin splitting, Coupling constant, Complex spin-
spin splitting, First order and non-first order spectra, Vicinal, geminal, ortho-,
para- and meta- coupling, Proton exchange reactions, Rotation about single
bonds, Variable temperature spectra, Geminal and vicinal coupling-
nonequivalence of protons relaxations, Simplification of complex spectra, LSR &
spin decoupling, New techniques in FT-NMR. NOE-difference spectra, 2D
techniques: COSY, NOESY, HETCOR, 13
C spectroscopy, Operating frequency, 1H decoupling, Off resonance decoupling, Broad band and gated- decoupling
DEPT, Special pulse techniques.
4. Mass Spectrometry: Ionization of a molecule on electron impact, The principles
of mass spectrum, Detection of the presence of the isotopes, Recoganization of
molecular ion peak, Reason for the loss of molecular ion peak, Metastable ions,
Fragmentations: McLafferty rearrangement, Nitrogen rule, Mass spectra of
different classes of organic and organometallic compounds, CI, EI and FAB mass
spectrometry, TOF- techniques.
5. Structure elucidation: By combined UV, IR, NMR (1H and
13C) and Mass
Spectra.
Books Recommended:
1. D.L. Pavia, G.M. Lampman, G.S. Kriz, Introduction to Spectroscopy, Thomson
Brooks/Cole.
2. P.S. Kalsi, Spectroscopy of Organic Compounds, New Age.
3. D.H. Williams and I. Fleming, Spectroscopic Methods in Organic Chemistry, Tata
McGraw-Hill, New Delhi.
4. H. Duddeck and W. Dietrich, Structure Elucidation by Modern NMR, Springer
Verlag.
5. W. Kemp, Organic Spectroscopy, Macmillan, London.
6. V.R. Dani, Organic Spectroscopy, Tata McGraw Hill Publishing. Company, New
Delhi.
Page 58 of 72
7. R. Chang, Basic Principles of Spectroscopy, McGraw Hill.
8. R.M. Silverstein, G.C. Bassler and T.C. Morrill, Spectrometric Identification of
Organic compounds, John Wiley.
9. M.R. Islam and M. A. Huq, Modern NMR Spectroscopy (in Bangla), Ashrafia Bio
Ghar, Bangla Bazar, Dhaka.
10. M.R. Islam and M. A. Huq, Modern Mass Spectroscopy (in Bangla), Bangla
Academy, Dhaka.
Course Code: CHEM 4102
Biophysical Chemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Solutions: Electrolyte solutions: A molecular view of the electrolyte solution
process, Thermodynamics of ions in solution, Enthalpy, entropy and Gibbs energy
of formation of ions in solution; Nonelectrolyte solution: Partial molar quantities,
The thermodynamics of mixing, Real solutions; Ionic activity: Debye-Huckel
theory of electrolytes, The salting-in and salting-out effects; Hydration and
solvation, Structure breaker and structure makers, Effects of additives, pH and
ionization on solubility, The solubility parameter, Partitioning, Biological activity
and partition coefficient.
2. Bioenergetics: Bioenergetics and thermodynamics, Standard free energy change in
biochemical reactions, exergonic, endergonic, The standard states in biochemistry,
ATP-The currency of energy, Hydrolysis of ATP, Synthesis of ATP from ADP,
Principles of coupled reactions, Glycolysis, Limitations of thermodynamics.
3. Enzyme and drug kinetics: (a) Enzyme catalysis, Equation of enzyme kinetics,
Michaeles Menten kinetics, Steady state kinetics, significance of Km and Vmax,
Factors affect on enzyme kinetics, Chymotrypsin: A case study, multisubstrate
system: sequential mechanism, the non-sequential mechanism; Enzyme inhibition:
Reversible inhibition, Irreversible inhibition. (b) Regulations of enzyme-catalyzed
reactions rates drugs, time course of drug action; intake and elimination of drugs;
theories of drug-effect connection.
4. Biological Membrane: Biological membrane: constituent and structure, Fluid
mosaic model, Factors affects the physical properties of membrane, Principles of
membrane transport: active and passive transport, Donnan equilibrium; dialysis;
equilibrium dialysis.
Books Recommended
1. R. Chang, Physical chemistry for Biosciences, University Science Books,
California, 2005.
2. D. L. Nelson and M. M. Cox, Lehninger Principles of Biochemistry, W. H.
Freemann and Company, New York.
3. P. Atkins and J. D. Paula, Physical Chemistry for the Life Sciences, W. H.
Freemann and Company, New York.
4. Alberts, Molecular Biology of the Cell, Sixth Edition, Garlands Science.
5. P.R. Bergethon & F. R. Simons, Biophysical Chemistry, , Springer Verlag
N.Y.
Page 59 of 72
6. T. Devasena, Enzymology, Oxford University Press 2010
Course Code: CHEM 4103
Solid State Chemistry and Crystallography
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Solids: Solid state: properties of solids, crystalline and amorphous solids,
distinction between crystalline and amorphous solids, classification of crystalline
solid, isomorphism, polymorphism and allotropy, molecular crystal (van der
Waals crystals), covalent crystals, ionic crystals, metallic crystals, hydrogen
bonding in crystals; Born-Haber cycle; Liquid crystal: types of liquid crystal,
application of liquid crystal. Space lattice: Bravais indices, Miller indices; Hauy’s
law; unit cell: different types of unit cell, calculation of number of atoms in unit
cell, radius ratio and coordination number; symmetry of elements: plane of
symmetry, axis of symmetry, centre of symmetry. Some important structure of
crystal: Sodium chloride, Zinc blend, Diamond, Wurtzite, Pervoskite and Spinel
structure.
2. Crystal Defects: Perfect crystal, defects in solids, vacancies, classification of
crystal defects: point defects, intrinsic and extrinsic point defects, line defects,
plane defects, electronic defects, excitation state of crystal, transient defects,
stoichiometric and non-stoichiometric defects: Schottky defects, Frenkel defects,
influence of defects on the physical properties of solids, color centers.
3. X-ray Crystallography: Crystallography: crystal systems, crystallographic axis
and axial ratio, law of constancy of interfacial angles, Bragg’s law, important of
Bragg’s law, Laue function and Laue condition, oscillating crystal method,
structure of NaCl, CsCl and CaF2 by Bragg’s law, X-ray diffraction of crystal,
Powder XRD: Theory, Equipment, X-ray source, Sample preparation and
applications, Single crystal X-ray diffraction, Debye-Scherrel equation, Principle
of neutron and electron diffraction.
4. Electrical Properties of Crystals: Band theory of solid, Band structure of metal,
Hall effect, Hall effect and types of semiconductor, Origin of band gap:
conductor, semiconductor and insulator, hole concept, dopping, impurities on
semiconductor: intrinsic and extrinsic semiconductor: p-type and n-type
semiconductor, non-stoichiometric metal oxides, superconductor.
Books Recommended
1. Anthony R. West, Solid State Chemistry and its Applications, Wiley
2. A. R. Verma, Crystallography Applied to Solid State Physics, New Age
International Publishers.
3. D. K. Chakrabarty, Solid State Chemistry, New Age International Publishers.
4. Gurdeep Raj, Advanced Physical Chemistry, Goel Publishing House, 2007
5. P. Atkins and J. Paula, Atkins Physical Chemistry, (8th
edition) W. H.
Freeman and Company, New York
Page 60 of 72
Course Code: CHEM 4104
Environmental Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Biogeochemical Cycles: Carbon transport in the major world rivers with
particular reference to Bangladesh, Sulphur and nitrogen cycles, Biogeochemical
parameters of different soil zones of Bangladesh.
2. Chemistry of the Air Environment: Composition of atmosphere, Types of
chemical pollutants in air and their sources, Chemical and photochemical
reactions and their consequent effects; Environmental effects of oxides of carbon,
nitrogen and sulfur, hydrocarbons and ozone, Metallic particulates in the
atmosphere, The automobiles as polluter, Acid rain, Environmental radioactivity.
3. Green House Effect (Global Warming and its mechanism): Green houses
gases, Sources and sinks, Green house potential of different gases, Consequences
of green houses effect: global and Bangladesh perspective, Remedial actions to be
taken for offsetting the greenhouse effect.
4. Ozone Layer Depletion: Causes and mechanism, CFC’s and their role, Chemical
formulae of CFCs from numbers chemistry of ozone depletion in stratosphere,
ODP, Implications of Ozone depletion, Remedial Measures, Montreal treaty and
other international treaties for protecting the ozone layer, Air particulate matters,
Aerosols: theirs primary sources and effects on human health.
5. Chemistry of the Water Environment: Sources of water pollution, Classes of
polluted water, Standard for drinking water, Measuring DO, BOD, COD, and
DOC, Mobilization of arsenic in ground water, Arsenic and human health,
Bangladesh scenario, Oceanic dumping, Effects of pollution on oceans, Sewerage
and its effects, Sewerage treatment.
6. Environmental Pollution in Agriculture: Definition and types; Structure and
properties of different pesticides, Mode of action of pesticides, Toxicity, Toxicity
rate, MLD, LD50, and pT, Behavior of pesticides in soil, Organochlorine
compounds, Organophosphates and carbamates, Effects of pesticides on
environment, Integrated pest management (IPM), Environment friendly
insecticide and pesticides. Agro-chemicals, uses and misuses, Bangladesh
perspective, Need for the development and use of comprehensive slow release
chemical fertilizers, Micronutrients in soil.
7. Waste Treatment: General understanding of waste in society, Wastes in various
industries, Carriers of wastes: solid, water and other liquids and gas, General
principles of waste treatment, Treatment in dye, tanning and other industries
relevant to Bangladesh, Municipal and industrial wastes, Waste utilization,
Recycling strategy: principles and practice, environmental laws & acts.
Books Recommended:
1. Stanley E. Manahan, Fundamentals of Environmental Chemistry, CRC Press.
2. L.T. Pryde, Environmental Chemistry, Cummins.
Page 61 of 72
3. R.W. Raiswell, P. Brimblecombe, D.L. Dent and P.S. Liss, Environmental
Chemistry, Wiley.
4. J.W. Moore and E. A. Moore, Environmental Chemistry, Academic Press.
5. Werner Stumm and James J. Morgan, Aquatic Chemistry, Wiley-Interscience.
Course Code: CHEM 4105
Green Chemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Principles and Concepts of Green Chemistry: Introduction; Theory and
practice; Sustainable development and green chemistry; Green engineering;
Difference between green chemistry and environmental chemistry.
2. Atom Economy and Waste Prevention: Percent of yield of a reaction; E-factor;
A measure of the efficiency of a reaction; Waste-minimization techniques.
3. Ionic Liquids and Energy Efficiency: Organic solvents; Safer solvents and
auxiliaries; Supercritical fluids; Water as a reaction solvent; Solvent free
synthesis; Design for energy efficiency.
4. Catalysis and Green Chemistry: Introduction to catalysis; Role of catalysis,
Catalytic reactions and synthesis; Biocatalysis; Photocatalysis.
5. Greening up the Suzuki Reaction: Suzuki reaction and its application;
Limitations of Suzuki reaction; Recent works to greening up Suzuki reaction.
6. Sonochemistry and Microwave Assisted Synthesis: Introduction; Ultrasound;
Principles of sonochemistry; Sonochemical synthesis; Microwave as energy
source; Microwave as a tool for synthetic chemistry; Limitations of microwave
chemistry; Application of microwave in organic synthesis.
7. Energy and Chemicals from Renewable Resources: Energy from biomass;
Solar power; Biosynthesis of ethanol from molasses; Chemicals from fatty acids;
Adipic acid, Maleic acid, Glycerol and Sorbitol from natural resources.
Books Recommended
1. R.A. Sheldon, I. Arends and U. Hanefeld, Green Chemistry and Catalysis, Wiley-
VCH.
2. M. Lancaster, Green Chemistry: An introductory text, Third edition, Royal
Society of Chemistry.
3. S.C. Ameta and R. Ameta, Green Chemistry: Fundamentals and applications,
CRC Press, Taylor & Francis Group.
4. P.T. Anastas and J.C. Warner, Green Chemistry: Theory and Practice, Oxford
University Press: New York, 1998, p.30. By permission of Oxford University
Press.
5. J.E. Thompson, Biosynthesis of Ethanol from Molasses, Science Division, Lane
Community College, 2006.
Page 62 of 72
Course Code: CHEM 4106
Theoretical Organic Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Acids and Bases: Effect of solvents on the strength of acids and bases,
Hammett’s acidity function, Grunwald-Acidity scale, Effect of structure on the
strength of acids and bases, Acid base catalysis: specific and general acid
catalysis, specific base catalysis, Brönsted catalysis law, Mechanism of acid and
base catalysis.
2. Structure and Reactivity: Quantitative treatment, The Hammett-Equation,
Significance of σx and ρ, Modification of σ, σx+, σx
-, Yukuwa-Tsuno equation,
Taft equation, Solvent effect, Grunwald-Winstein equation, Dirmoroth’s Er
parameter, Uses of Hammett plots, Spectroscopic correlations, Thermodynamic
implication.
3. Free Radical Reaction: Long lived and short lived free radicals: production and
detection of free radicals, configuration of free radicals, type of free radical
reactions and general characteristics, Homolysis and free radical displacements:
free radical halogenation, iodine exchange reactions, Sandmeyer reaction,
additions and rearrangements of free radicals, polymerization, Homolytic
elimination and cyclizations.
4. Rearrangement Reactions: Electron deficient skeletal rearrangement,
Mechanism and energy diagram of 1,2-shift, Non-classical carbonium ion,
Detection and stereochemistry of rearrangement, Migration to carbon: Wagner-
Meerwein, pinacol, and related rearrangements, Migration to nitrogen: Hofmann
Lossens, Curtius Schmidt, Beckmann rearrangements, Electron rich
rearrangements, Setevens-Favorskii rearrangements, Transannular reactions.
5. Orbital Symmetry Controlled Reactions: Frontier Orbital concept, T.S.
concept-Huckel & Mobius T.Sr., Correlation diagram, Electrophilic reaction,
Sigmatropic reaction, Analysis of electrophile, Cycloaddition and sigmatropic
reactions, Anionic oxy-Cope reactions, Cope and Claisen rearrangements.
6. Photochemistry: Theory of photochemistry, Electronic transitions,
Photosensitization by energy transfer, Photoaddition Photoreduction, Substitution
reactions fragmentation and rearrangement, Photochemical reactions of
conjugated aromatic and heterocyclic systems, configuration free radical
detection, etc.
Books Recommended:
1. Francis Carey and J. R. Sundberg, Advanced Organic Chemistry, Part A & B,
Plennum Press, New York and London.
2. T.H. Lowry and K. S. Richardson, Mechanism and Theory in Organic Chemistry,
Harper Collins Publishers, Inc., New York.
3. M.B. Smith, Organic Synthesis, McGraw-Hill, Inc., New York.
4. P. Sykes, A Guide Book to Mechanism in Organic Chemistry, Longman.
5. J. March, Advanced Organic Chemistry, McGraw-Hill.
6. J. Hine, Physical Organic Chemistry, McGraw-Hill.
Page 63 of 72
7. C.K. Ingold, Structure and Mechanism in Organic Chemistry, Bell & Sons, Ltd.,
London.
8. D.C. Nonhebel and J.C. Walton, Free Radical Chemistry, Cambridge Univ. Press.
9. P de Mayo, Molecular Rearrangement, Inter Science.
10. J. Kopecký, Organic Photochemistry: A Visual Approach, Wiley-VCH Verlag
GmbH.
11. Orbital Symmetry, Gilchrist
12. Structure and Mechanism in Organic Chemistry, E.S. Gould
Course Code: CHEM 4107
Chemistry of Natural Products
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Natural Products: Definition, occurrence and importance of some natural
products, General methods of isolation, purification and determination of structure
of natural products by chemical and spectroscopic methods.
2. Alkaloids: Occurrence, classification, extraction and purification of alkaloids,
General methods of determining structure, Chemistry of ephedrine, atropine and
cocaine, Biosynthesis of alkaloids.
3. Terpenoids: The essential oils, Classification of terpenes, Isoprene rule, Isolation
and purification, General methods of determining structures of terpenes, Detailed
studies of some monoterpenes, (i) acyclic monoterpenes: myrcene, citral, (ii)
monocyclic monoterpenes like limonene, (iii) bicyclic monoterpenes like α-
pinene, camphor, Biosynthesis of monoterpenes.
4. Steroids and Hormones: Introduction of steroids and hormones, Nomenclature
and functions of steroids and hormones, Structure of Cholesterol and its effect in
biological systems, Steroidal hormones and glycoisides, Natural and synthetic
hormones.
5. Flavonoids: Anthocyanins, flavones, xanthenes and other derivatives. Naturally
occurring coloured compounds: chlorophyll and haemoglobin.
6. Pheromones: Pheromones, Their stereo-specificity and action in biological
systems.
7. Antibiotics: Chemistry of penicillin and chloramphenicol.
Books Recommended:
1. I.L. Finar, Organic Chemistry Vol. II, Longmans, Green & Co.
2. K.B.G. Torssell, Natural Product Chemistry, John Wiley and Sons, New York.
3. G.A. Wawan, An Introduction to the Alkaloids, Blackwell.
4. P. de Mayo, Mono & Sesqui-terpenes, Inter Science.
5. S.W. Pettetier, Chemistry of the Alkaloids, von Nostrand Renihold.
6. Fleming, Selected Organic Synthesis, John Wiley and Sons, New York.
7. P.S. Kalsi, Natural Product Chemistry, Kalyani Publishers, New Delhi.
Page 64 of 72
8. O.P. Agarwal, Chemistry of Organic Natural Products, Vol I & II, Goel
Publishing House.
9. Agarwal Vol. I & II.
Course Code: CHEM 4108
Organo-applied Chemistry Laboratory
(Full Marks: 20 + 10 + 70 = 100; 1.5 Credits)
1. Analysis of Fats and Oils: Determination of acid value, iodine value and
saponification value of supplied oil (soybean oil, palm oil, olive oil)/fat.
2. Analysis of sugar: Determination of reducing sugar (glucose) and non-reducing
sugar (sucrose) content in supplied sample (molasses, juice, cane sugar, etc.).
3. Soap and Detergents: Analysis of total acid, total alkali, free acid and free alkali
value of supplied soap or detergent.
4. Food and Drink: Analysis of milk for sugar and protein.
1. Quantitative Estimation of Functional Groups in the Organic Compounds: (i)
Hydroxyl groups (phenols and alcohols), (ii) Carbonyl groups (aldehydes and
ketone), (iii) Carboxylic acid group, (iv) Amino group.
2. Periodic Oxidation: Action of polyhydric alcohols both by acidometric &
iodometric titrations.
3. Chrometographic Analyses: TLC, Simple separation by Column Chromatography,
Analyses of sugars & amino acids by paper chromatography.
N. B.: Experiments may be added to or omitted from the above list if necessary.
Course Code: CHEM 4109
Chemistry Research Methodology
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Fundamentals of Research: Aim and scope, Brief idea about research, Research
process, Research objectives, Research question and hypothesis, Research
problem and Non-research problem.
2. Literature Review: Chemical abstract review, Journals related to chemical
science.
3. Research Design: Research design and its types, Experimental and non-
experimental design, Validity in experiments.
4. Sample Design: Sample design, Types of sampling procedures.
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5. Research Proposal: Proposal development, Components of research proposal.
6. Writing scientific papers and reports: Format of scientific report, Details of
writing scientific report.
Books Recommended
4. W.G. Cochran and G.M. Cox, Experimental Design, John Wiley and Sons Inc.,
London.
5. M. Nurul Islam, (2011), An Introduction to Research Methods (2nd ed.), Mullick
and Brothers, New Market, Dhaka.
6. M. Nurul Islam, (2011), An Introduction to Sampling Methods (Rev. ed.), Mullick
and Brothers, New Market, Dhaka.
7. O.N. Bishop, Statistics for Biology, A Practical Guides for the Experimental
Biologists, Longman, UK.
Page 66 of 72
Course Code: CHEM 4201
Quantum Chemistry and Statistical Thermodynamics
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
SECTION-A: QUANTUM CHEMISTRY
1. Development of Quantum Mechanics: Failure of classical mechanics, Black
body radiation, Photoelectric effect, Compton effect, Planck’s quantum theory, de
Broglie concept of dual nature of electron/Wave particle duality, Heisenberg
uncertainty principle, Interpretation of wave function, Postulates of quantum
mechanics, Operators, Eigen value and eigen function, Normalization,
Orthogonality, Schrödinger wave equation.
2. Application of Quantum Mechanics: Schrodinger’s equation for one electron
system, Solution of Schrodinger’s equation for a free particle and particle in a one
and three dimensional box, Calculation of energy and wave function. Application
of Schrödinger equation to the hydrogen atom in a spherical polar coordinates,
Separation of variables, Significance of Φ(ϕ), Θ(θ) and R (r) equation, Quantum
numbers and total energy of an orbital, Space wave function and radial
distribution function.
3. Approximate Methods: Perturbation method, Variation method and self consistent
field method, Application of approximate methods for calculating energies of
helium atom, hydrogen molecule ion and hydrogen molecule.
SECTION-B: STATISTICAL THERMODYNAMICS
1. Probability Distribution of Particles: Probability and thermodynamic
probability, Probability distribution of particles in energy states, Most probable
distribution, Maxwell-Boltzmann statistics, Bose-Einstein statistics, Fermi-Dirac
statistics,
2. Partition Function: Definition and physical significance of partition function,
Separation of partition function, Translational, Rotational, Vibrational,
Electronic, and total partition function, Relationship between partition functions
and thermodynamic functions. Molar partition function, Application of partition
function to monoatomic and diatomic molecules, Statistical expression for
equilibrium constant, Equipartition of energy.
3. Application of Thermodynamics: Derivation of Maxwell-Boltzmann distribution
law. Electron gas in metals, Specific heat of solids, Einstein and Debye theory of
specific heat.
Books Recommended
1. B. H. Bransden and C. J. Joachain, Quantum Mechanics, Pearson.
2. R. L. Liboff, Introductory Quantum Mechanics, Pearson.
3. S. Prakash, Quantum Mechanics, Pragati Prakashan.
4. K. Singh and S. P. Singh, Elements of Quantum Mechanics, S. Chand &
Company Ltd.
5. C. L. Tien and J. H. Lienhard, Statistical Thermodynamics, Hemisphere
Publishing Corporation, New York.
6. N. M. Laurendeau, Statistical Thermodynamics: Fundamentals and
Page 67 of 72
Applications, Cambridge University Press, 2005.
7. R. Fitzpatrick, Thermodynamics and Statistical Mechanics.
8. Gurdeep. Raj, Advanced Physical Chemistry, Goel Publishing House, 2007.
Course Code: CHEM 4202
Organometallic Chemistry
(Full Marks: 20 + 10 + 70 = 100; 3 Credits)
1. Introduction: Historical background, Classification of organometallic
compounds by bond type, Difference between main groups and transition metal
organometallics, The stability of organic compounds.
2. Main Group Organometallics: Synthesis of Organometallic compounds
containing Lithium, Magnesium, Cadmium, Copper, Zinc and their synthetic
utility.
3. Transition Metal Organometallics: Classification of organic ligands, 18-
electron rule and its basis, application and exceptions.
4. Metal carbonyls, Metal nitrosyls and Metal Phosphines: Synthesis, Structures,
bonding and reactions.
5. Synthesis, Bonding, Structures and Properties (including fluxional behavior)
of the Following Types Transition Metal Organometallics:
(a) Compounds with 1-electron ligands: σ-alkyl, aryl, and halide complexes.
(b) Compounds with 2-electron ligands: alkene compounds.
(c) Compounds with 3-electron ligands: η3-allyl complexes.
(d) Compounds with 4-electron ligands: tricarbonyliron complexes of dienes and
alkynes.
(e) Compounds with 5-electron ligands: cyclopentadienyl complexes.
6. Metal-Metal Bonding and Metal Clusters:
(a) Transition Metal Carbonyl Clusters: Structure, Synthesis and Reactions,
(b) Synthesis, Structure and Substitution Reactions of Trimetallic
Dodecacarbonyls of Osmium.
1. (a) Stoichiometric Reactions of Transition Metal Organometallics: Oxidative
addition, Reductive elimination and Insertion reactions.
(b) Catalytic Reactions of Transition Metal Organometallics: Water gas shift
reaction, Fischer-Tropsch synthesis, Hydroformylation reaction, Homogeneous
hydrogenation of unsaturated compounds, Ziegler-Natta polymerization of
ethylene and propylene.
Books Recommended:
1. G.E. Coates, M.L. Green, P. Powell and K. Wade, Principles of Organometallic
Chemistry, Methuen and Co. Ltd.
Page 68 of 72
2. M. Bochmann, Organometalics 1: Complexes with Transition Metal-Carbon σ-
bonds, Oxford Science Publications.
3. M. Bochmann, Organometalics 2: Complexes with Transition Metal-Carbon π-
bonds, Oxford Science Publications.
4. A.W. Parkins and R.C. Poller, An Introduction to Organometallic Chemistry,
Macmillan Publishers Ltd.
5. G.E. Coates, M.L. Green, and K. Wade, Organometallic Compounds, Vol. 1 & 2,
Methuen and Co. Ltd.
6. B.F.G. Johnson (ed.): Transition Metal Clusters, Wiley-lnterscience.
7. K. Kundu, Elementary Organometallic Chemistry, Bangla Academy, Dhaka.
Course Code: CHEM 4203
Nanochemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Introduction: About size scales, history, Feynman scorecard, Schrodinger’s cat-
quantum mechanics in small systems, fluctuations and “Darwininian
nanoscience”, quantum effects and fluctuations in nanostructures, microscopy and
manipulation tools in nanochemistry.
2. Synthesis of Nanomaterials: Top-down approach: Photolithography, electron
beam lithography, micromechanical structures, thin film technologies, molecular
beam epitaxy, focused ion beam milling, Bottom-up approach: Common aspects
of all assembly methods, laser vaporization technique, chemical bath deposition
method, chemical vapor deposition technique, laser ablation technique, organic
synthesis, electrodeposition, spin coating, DNA nanotechnology.
3. Chemical interaction: Chemical interaction at the nanoscale: electrostatic
interaction, hydrogen bonding, van der Waals attractions, hydrophobic effects,
4. Experimental techniques: Experimental techniques in nanochemisrty: Scanning
electron microscopy, Transmission electron microscopy, Atomic force
microscopy, Scanning tunneling microscopy, X-ray method, UV-vis and Infrared
spectroscopy, Light seafaring method for particle sizing, techniques for surface
area and porosity measurements.
5. Nonmaterials: Fullerenes, Carbon nanotubes, Graphene, Dianmondoids,
6. Application: Application of nano materials in catalysis, oxide reactions, in
sensors and electronic devices, photochemistry, composite, coatings, energy,
environment, food, agriculture, textile and medicine,
7. Environmental implications: Nanotoxicology, risk assessment and
environmental aspects.
Books Recommended
1. Nanochemistry, by G. B. Sergeev, Elsevier, 2006.
Page 69 of 72
2. Introduction to Nanoscience, by Gabor L Hornyak, Joydeep Dutta, Harry F
Tibbals, Anil K Rao, CRC press, 2008.
3. Applied Nanotechnology, by Jeremy J Ramsden, William Andrew, 2009.
4. Nanoscale Material in Chemistry, Ryan M. Richards
5. S. M. Lindsay, Introduction of Nanoscience, Oxford University Press, UK,
2010.
6. G. Cao, Nanostructures and Nanomaterials: Synthesis, Properties &
Applications, Imperial College Press, 2004.
7. A. Hirsch, M. Brettreich, F.Wudl, Fullerenes: Chemistry and Reactions, John
Wiley & Sons, 2005.
Course Code: CHEM 4204
Bioinorganic Chemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Introduction: General aspects, Metal ions in biological systems, Trace and
ultratrace metals, Role of metal ions in biological systems, Metallobiosite
structures, Ion pumps.
2. Functional Value of the Chemical Elements in Biological Systems: Major
chemical properties of chemicals in aqueous solution, Biochemical functions of
the chemical elements, The living process, Chemical flow in biology, Na+/K
+
pump.
3. Metal Management and Electron Transfer: Iron storage and iron transport,
Ferritin, Haemosiderin, Transferrins, Siderophores, Metallothioneins and
phytochelatins, Ceruloplasmin, Vanadium storage and transport, Inner-sphere and
outer-sphere electron transfer, Blue copper proteins: plastocyanin, azurin, etc.,
Iron-sulphur proteins: rubredoxins, ferrodoxins, and other models, synthetic
models for Fe-S proteins, Cytochtomes.
4. Dioxygen Management:
(a) Storage and Transport: Metalloporphyrins: chlorophyll, heme proteins,
Haemoglobin and Myoglobin-model systems, the structures of the natural
sites, cooperativity, synthetic blood, Haemerythrin and haemocyanin, other
heme proteins.
(b) Involvement in Enzymes: Superoxide dimutases, Peroxidases and
catalases, Oxidases and oxygenases, Ribonucleotide reductase, Zinc,
Superacids, Structural role of zinc in proteins, Vitamin B12, Nitrogenases,
Oxotransfer molybdoenzymes, Nickel enzymes, Role of Cu, Co, Zn, V, and
Mo in biologically important reactions.
5. Metals and Health: The application of therapeutic chelating agents, Platinum and
anticancer activity, cis-platin, carboplatin, Gold and antiarthritic agents, auranofin,
etc,
Page 70 of 72
6. Metal Toxicity: Iron overload, Copper, Mercury, Cadmium and Lead toxicity,
Mercuric ion reductase, Lead and porphobilinogen synthase, Metals as
Carcinogens.
Books Recommended
1. D.E. Fenton, Biocoordination Chemistry, Oxford University Press.
2. F.A. Cotton, G. Wilkinson and P.L. Gaus, Basic Inorganic Chemistry, Wiley-
India.
3. J.A. Cowan, Inorganic Biochemistry: An Introduction, Wiley-VCH, New York.
4. S.J. Lippard and J.M. Berg, Principles of Bioinorganic Chemistry, University
Science Books, Mill Valley, California, USA.
5. I. Bertini, H.B. Gray, S.J. Lippad, J.S. Valentine, Bioinorganic Chemistry,
University Science Books, Mill Valley, California, USA.
Course Code: CHEM 4205
Organic Reagents and Syntheses
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. Oxidation: Oxidation reactions with Cr, Mn compounds, SeO2, Pb(OAc), and
peracid, periodate.
2. Reduction Reactions: Catalytic hydrogenation, Reduction with dissolving
metals, Metal hydrides LiAlH4, NaBH4.
3. Interconversion of Functional Groups: (a) Interconversion of function groups,
Transformation of alcohols, Phenols, Halogeno compounds, Nitro compounds,
Acids and acid derivatives, (b) Protective groups: the strategy, protection of
alcohols, diols, carboxylic acids, amino group, carbonyl groups, their applications
in organic syntheses.
8. Formation of Carbon-Carbon Bonds: The principles, Reactions of
organometallic compounds, Grignard Reagents, Organocopper reagents, The use
of stabilized carbanions and related nucleophiles, Formation of carbon-hetero
atom bonds, Umpolung yields, Stereo selective enolate reactions, Enamines,
Michael addition and Robinson annulation, Heck reaction, Suzuki reaction, Stille
coupling, Wittig reaction, Reformatsky reaction.
6. Combinatorial Chemistry: Introduction, Principles of combinatorial chemistry,
Methods and techniques of combinatorial synthesis (Library synthesis), Solid
phase organic synthesis, Solution phase combinatorial chemistry, Solid phase
synthesis of peptides, Hyper-valent iodines and their applications.
6. Strategy in Synthesis: The disconnection approach to synthesis, Concept of a
synthon, Functional group interconversions, Reagent, Synthetic equivalent and
target molecule, Synthesis of monofunctional and difunctional compounds: (a)
one-group disconnection, disconnection of simple alcohol compounds derived
from alcohols, disconnection of simple olefins, ketones, (b) (i) two group
disconnections- 1,3-dioxygenated skeletons, (ii) ‘Illogical’ two group
Page 71 of 72
disconnection, the 1,2-dioxygenation pattern, (c) pericyclic reactions, (d)
heterocyclic compounds, Strategy considering all possible disconnections.
Books Recommended:
1. R.K. Mackie and D.M. Smith, Guidebook to Organic Synthesis, Longman.
2. W. Carruthers, Some Modern Methods of Organic Synthesis, Cambridge
University Press.
3. H.O. House, Modern Synthetic Reactions, Benjamin-Cummings.
4. J. March, Advanced Organic Chemistry, Reactions, Mechanisms and
Structure, John Wiley & Sons.
5. M.B. Smith, Organic Synthesis, McGraw-Hill.
6. S. Warren, Designing Organic Synthesis, John Wiley & Sons.
7. G. Jung, Combinatorial Chemistry: Synthesis, Analysis, Screening, Wiley-
VCH, New York.
Course Code: CHEM 4206
Medicinal Chemistry
(Full Marks: 20 + 10 + 70 = 100; 2 Credits)
1. General Introduction to Medicinal Chemistry: Classification of drugs, sources,
prodrugs, lead compounds, necessity of new drugs.
2. Drug Action: The pharmaceutical phase, the pharmacokinetic phase and the
pharmacodynamic phase. Methods and routes of administration, ADME, Routes
of elimination, Bioavailability.
3. Drug Design: Stereochemistry and drug design, structure-activity relationships
(SAR), Quantitative structure-activity relationship (QSAR), Hansch analysis,
Bioisosteres.
4. Receptors and Messengers: Structure and classification of the receptors,
Agonist, Antagonist and partial-agonist, primary and secondary messengers,
Neurotransmitters, Ligand-receptor theories.
5. Drug Metabolism: Introduction, aim, site of metabolism, factors affecting
metabolism, phase I and phase II reactions.
6. Drug Discovery, Development and Production.
7. Chemical and Biological Aspects of the Following Classes of Drugs: (a) Local
Anaesthetics (procaine, tetracacine, lidocine), (b) Sulfadrugs (sulfamethoxazole,
sulfanilamide, sulfadiazine), (c) Antibiotics (β-lactum, ampicillin, amoxicillin,
cloxacillin, floxacillin), (d) Anticancer agents (mechloroethamine, 5-flurouracil,
methotrexale, doxorubicin, vincristin), (e) Antidiabetic agents (insulin,
tolbutamide, glyburide), (f) Cardiac agents (cardiac glycosides, digitoxin,
digoxin), (g) Central nervous system stimulants (amphetamine, caffeine), and (h)
Depressants (diazepam, barbiturates, propofol, ketamine).
Page 72 of 72
Books Recommended
1. M.E. Wolff (ed.): Burger’s Medicinal Chemistry, John Wiley & Sons, New
York.
2. W.E. Foye (ed.): Principles of Medicinal Chemistry, Varghese Publishing
House, Mumbai.
3. Gareth Thomas: Medicinal Chemistry; An Introduction, John Wiley & Sons.
4. G.L. Patrick: An Introduction to Medicinal Chemistry, Oxford University
Press.
5. J.H. Block & J.M. Beale (Ed.): Wilson and Gisvold’s Textbook of Organic
Medicinal and Pharmaceutical Chemistry, Lippincott, Williams and Wilkins.
6. J.B. Taylor & P.D. Kennewell, Introduction of Medicinal Chemistry, Ellis
Horwood. UK.