Transcript
  • 1 Chronic Conditions: All cancers

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 25658 20433 79.6 4158 16.2 5581 21.8 5539 21.6 3265 12.7 1890 7.4 4385 17.1 1868 7.3

    Age at baseline

  • 2 Chronic Conditions: All cancers

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Radiation, no chemotherapy

    1087 984 90.5 121 11.1 245 22.5 228 21.0 238 21.9 152 14.0 301 27.7 138 12.7

    Chemotherapy and radiation

    5805 4747 81.8 859 14.8 1339 23.1 1234 21.3 793 13.7 522 9.0 1083 18.7 474 8.2

    Unknown 1478 1123 76.0 250 16.9 273 18.5 273 18.5 159 10.8 168 11.4 219 14.8 71 4.8

    Females All cases 11936 9822 82.3 1855 15.5 2636 22.1 2786 23.3 1671 14.0 874 7.3 2294 19.2 1007 8.4

    Age at baseline

  • 3 Chronic Conditions: All leukemias

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 7872 5889 74.8 1426 18.1 2048 26.0 1292 16.4 739 9.4 384 4.9 877 11.1 354 4.5

    Age at baseline

  • 4 Chronic Conditions: All leukemias

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Radiation, no chemotherapy

    3 1 33.3 . . 1 33.3 . . . . . . . . . .

    Chemotherapy and radiation

    2066 1622 78.5 344 16.7 561 27.2 361 17.5 234 11.3 122 5.9 287 13.9 119 5.8

    Unknown 441 305 69.2 75 17.0 100 22.7 61 13.8 38 8.6 31 7.0 38 8.6 11 2.5

    Females All cases 3672 2856 77.8 655 17.8 987 26.9 671 18.3 359 9.8 184 5.0 445 12.1 185 5.0

    Age at baseline

  • 5 Chronic Conditions: ALL

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 6615 4863 73.5 1253 18.9 1701 25.7 1025 15.5 590 8.9 294 4.4 660 10.0 252 3.8

    Age at baseline

  • 6 Chronic Conditions: ALL

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Unknown 381 257 67.5 64 16.8 84 22.0 53 13.9 35 9.2 21 5.5 29 7.6 9 2.4

    Females All cases 3053 2332 76.4 575 18.8 814 26.7 523 17.1 278 9.1 142 4.7 325 10.6 123 4.0

    Age at baseline

  • 7 Chronic Conditions: AML

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 927 759 81.9 129 13.9 268 28.9 192 20.7 112 12.1 58 6.3 154 16.6 72 7.8

    Age at baseline

  • 8 Chronic Conditions: AML

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Females All cases 473 397 83.9 67 14.2 137 29.0 104 22.0 59 12.5 30 6.3 88 18.6 46 9.7

    Age at baseline

  • 9 Chronic Conditions: All CNS

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 4489 4010 89.3 600 13.4 1026 22.9 1040 23.2 1041 23.2 303 6.7 1145 25.5 559 12.5

    Age at baseline

  • 10 Chronic Conditions: All CNS

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Radiation, no chemotherapy

    616 574 93.2 60 9.7 134 21.8 149 24.2 174 28.2 57 9.3 187 30.4 87 14.1

    Chemotherapy and radiation

    742 697 93.9 47 6.3 139 18.7 210 28.3 231 31.1 70 9.4 287 38.7 157 21.2

    Unknown 254 224 88.2 41 16.1 54 21.3 47 18.5 54 21.3 28 11.0 54 21.3 20 7.9

    Females All cases 2037 1838 90.2 265 13.0 473 23.2 492 24.2 482 23.7 126 6.2 528 25.9 259 12.7

    Age at baseline

  • 11 Chronic Conditions: Astrocytomas

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 2688 2345 87.2 434 16.1 599 22.3 545 20.3 591 22.0 176 6.5 604 22.5 290 10.8

    Age at baseline

  • 12 Chronic Conditions: Astrocytomas

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Radiation, no chemotherapy

    370 342 92.4 36 9.7 70 18.9 83 22.4 117 31.6 36 9.7 121 32.7 58 15.7

    Chemotherapy and radiation

    211 194 91.9 15 7.1 30 14.2 48 22.7 71 33.6 30 14.2 86 40.8 49 23.2

    Unknown 158 135 85.4 27 17.1 35 22.2 27 17.1 31 19.6 15 9.5 30 19.0 10 6.3

    Females All cases 1283 1144 89.2 202 15.7 292 22.8 271 21.1 298 23.2 81 6.3 297 23.1 144 11.2

    Age at baseline

  • 13 Chronic Conditions: Medulloblastoma/PNET

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 1040 983 94.5 70 6.7 206 19.8 339 32.6 291 28.0 77 7.4 395 38.0 199 19.1

    Age at baseline

  • 14 Chronic Conditions: Medulloblastoma/PNET

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Radiation, no chemotherapy

    115 111 96.5 9 7.8 30 26.1 34 29.6 30 26.1 8 7.0 41 35.7 21 18.3

    Chemotherapy and radiation

    437 417 95.4 22 5.0 89 20.4 135 30.9 134 30.7 37 8.5 178 40.7 94 21.5

    Unknown 48 44 91.7 6 12.5 8 16.7 12 25.0 13 27.1 5 10.4 12 25.0 4 8.3

    Females All cases 408 383 93.9 28 6.9 71 17.4 149 36.5 110 27.0 25 6.1 158 38.7 77 18.9

    Age at baseline

  • 15 Chronic Conditions: Hodgkin

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 3107 2658 85.5 340 10.9 730 23.5 541 17.4 468 15.1 579 18.6 761 24.5 351 11.3

    Age at baseline

  • 16 Chronic Conditions: Hodgkin

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Unknown 197 157 79.7 35 17.8 37 18.8 19 9.6 19 9.6 47 23.9 37 18.8 17 8.6

    Females All cases 1476 1340 90.8 121 8.2 322 21.8 306 20.7 303 20.5 288 19.5 470 31.8 226 15.3

    Age at baseline

  • 17 Chronic Conditions: NHL

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 2114 1569 74.2 356 16.8 431 20.4 424 20.1 210 9.9 148 7.0 269 12.7 100 4.7

    Age at baseline

  • 18 Chronic Conditions: NHL

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Radiation, no chemotherapy

    28 24 85.7 6 21.4 6 21.4 3 10.7 2 7.1 7 25.0 5 17.9 3 10.7

    Chemotherapy and radiation

    511 408 79.8 83 16.2 105 20.5 116 22.7 59 11.5 45 8.8 85 16.6 30 5.9

    Unknown 157 114 72.6 22 14.0 19 12.1 37 23.6 16 10.2 20 12.7 24 15.3 6 3.8

    Females All cases 678 556 82.0 117 17.3 174 25.7 138 20.4 76 11.2 51 7.5 96 14.2 40 5.9

    Age at baseline

  • 19 Chronic Conditions: Wilms

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 2275 1553 68.3 500 22.0 449 19.7 333 14.6 179 7.9 92 4.0 192 8.4 69 3.0

    Age at baseline

  • 20 Chronic Conditions: Wilms

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Chemotherapy and radiation

    499 355 71.1 104 20.8 102 20.4 70 14.0 49 9.8 30 6.0 47 9.4 21 4.2

    Unknown 108 72 66.7 30 27.8 18 16.7 9 8.3 6 5.6 9 8.3 9 8.3 2 1.9

    Females All cases 1255 879 70.0 251 20.0 253 20.2 224 17.8 102 8.1 49 3.9 123 9.8 40 3.2

    Age at baseline

  • 21 Chronic Conditions: Neuroblastoma

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 1947 1455 74.7 440 22.6 372 19.1 382 19.6 193 9.9 68 3.5 230 11.8 88 4.5

    Age at baseline

  • 22 Chronic Conditions: Neuroblastoma

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Radiation, no chemotherapy

    63 50 79.4 22 34.9 9 14.3 11 17.5 6 9.5 2 3.2 9 14.3 2 3.2

    Chemotherapy and radiation

    259 233 90.0 44 17.0 48 18.5 76 29.3 45 17.4 20 7.7 52 20.1 20 7.7

    Unknown 90 63 70.0 17 18.9 22 24.4 14 15.6 5 5.6 5 5.6 5 5.6 1 1.1

    Females All cases 997 759 76.1 221 22.2 186 18.7 204 20.5 111 11.1 37 3.7 138 13.8 59 5.9

    Age at baseline

  • 23 Chronic Conditions: STS

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 1756 1421 80.9 267 15.2 309 17.6 516 29.4 189 10.8 140 8.0 322 18.3 123 7.0

    Age at baseline

  • 24 Chronic Conditions: STS

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Radiation, no chemotherapy

    32 19 59.4 4 12.5 3 9.4 8 25.0 3 9.4 1 3.1 4 12.5 . .

    Chemotherapy and radiation

    521 444 85.2 71 13.6 98 18.8 165 31.7 54 10.4 56 10.7 103 19.8 42 8.1

    Unknown 111 79 71.2 21 18.9 17 15.3 22 19.8 10 9.0 9 8.1 15 13.5 4 3.6

    Females All cases 807 677 83.9 116 14.4 137 17.0 266 33.0 100 12.4 58 7.2 183 22.7 70 8.7

    Age at baseline

  • 25 Chronic Conditions: All bone

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 2098 1878 89.5 229 10.9 216 10.3 1011 48.2 246 11.7 176 8.4 589 28.1 224 10.7

    Age at baseline

  • 26 Chronic Conditions: All bone

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Radiation, no chemotherapy

    9 9 100.0 1 11.1 1 11.1 3 33.3 2 22.2 2 22.2 4 44.4 2 22.2

    Chemotherapy and radiation

    296 258 87.2 53 17.9 45 15.2 96 32.4 37 12.5 27 9.1 71 24.0 26 8.8

    Unknown 120 109 90.8 9 7.5 6 5.0 64 53.3 11 9.2 19 15.8 37 30.8 10 8.3

    Females All cases 1014 917 90.4 109 10.7 104 10.3 485 47.8 138 13.6 81 8.0 311 30.7 128 12.6

    Age at baseline

  • 27 Chronic Conditions: Ewings

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 738 621 84.1 127 17.2 130 17.6 213 28.9 82 11.1 69 9.3 158 21.4 62 8.4

    Age at baseline

  • 28 Chronic Conditions: Ewings

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Chemotherapy and radiation

    236 201 85.2 46 19.5 42 17.8 66 28.0 29 12.3 18 7.6 50 21.2 19 8.1

    Unknown 37 31 83.8 5 13.5 3 8.1 13 35.1 3 8.1 7 18.9 7 18.9 2 5.4

    Females All cases 353 300 85.0 58 16.4 62 17.6 98 27.8 43 12.2 39 11.0 86 24.4 37 10.5

    Age at baseline

  • 29 Chronic Conditions: Osteosarcoma

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Both sexes

    All cases 1257 1168 92.9 78 6.2 65 5.2 772 61.4 152 12.1 101 8.0 420 33.4 158 12.6

    Age at baseline

  • 30 Chronic Conditions: Osteosarcoma

    Maximum Grade

    Any chronic condition

    (grade 1-5) 1:Mild 2:Moderate 3:Severe 4:Disabling 5:Fatal 1

    Multiple severe

    conditions (>=2) 2

    Multiple severe

    conditions (>=3) 2

    All cases N % N % N % N % N % N % N % N %

    Unknown 79 75 94.9 3 3.8 2 2.5 51 64.6 8 10.1 11 13.9 29 36.7 8 10.1

    Females All cases 610 572 93.8 40 6.6 31 5.1 374 61.3 87 14.3 40 6.6 220 36.1 89 14.6

    Age at baseline


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