Transcript

1998 multi-membered N-heterocycles

multi-membered N-heterocyclesR 0690

03 - 176Synthesis and Antitumor Activity of Macroheterocyclic Compoundsand Their Metal Complexes. — The macroheterocyclic compounds(III), prepared from phthalonitrile (I) and diaminotriazine or -thiadiazine (II),form stable complexes with copper, cobalt or nickel ions. The metal complexesof compound (III) as well as the diamino compounds (II) are tested for theirantitumor activity. — (ISLYAIKIN, M. K.; DANILOVA, E. A.; KUDRIK, E.V.; SMIRNOV, R. P.; BUDUNOVA, A. P.; KINZIRSKII, A. S.; Khim.-Farm.Zh. 31 (1997) 8, 19-22; Ivanovskaya gos. khim.-tekhnol. akad., Ivanova, Russia;RU)

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