Oral Biofilm

ORAL BIOFILM

Oral Biofilm

A Biofilm is a community of microorganisms that adheres to substratum within a self-produced polysaccharide matrix and that show an altered phenotype compared to planktonic bacteria.

ORAL BIOFILM

Oral Biofilm

Microcolony 15-20% + Matrix 85-80%(water, bacterial cells,

proteins, exopolysaccharides , ….)

Essential for their functions

Oral Biofilm

The complexity of the bacteria SURVIVAL STRATEGY

Oral Biofilm

BIOFILM CONSEQUENCES?

Oral Biofilm

BIOFILM AND PERIODONTAL DISEASE

Polycaries

Oral Biofilm

BIOFILM MONOGRAPH

Oral Biofilm

New requirements in the therapeutic control of PD

The bacteria embedded in a biofilm are up to 1,000 times as resistant

Oral Biofilm

ANTISEPTIC MOUTHRINSES (affect the biofilm)

CHXCPC

TriclosanEssential oils

Hexetidine

IN VITRO TEST

(Artificial Mouth)

IN VIVO STUDIES

Oral Biofilm

In vitro studies (artificial mouth) CHLORHEXIDINE (CHX) greater bactericidal effect * but NOT all commercial brands showed the same efficacy (Herrera et al. 2003)

In vivo studies CHX mouthrinses able to penetrate the Biofilm and exert a greater bactericidal effect**. Mouthrinses with triclosan have little capacity to reduce the vitality of a biofilm (Arweiler)The effect of the CHLORHEXIDINE mouthrinses depended on their formulation. (Arweiler)

*In 2002 Shapiro compared the bactericidal capacity of CHX, Triclosan, Plant extracts, essential oils and hexetidine vs. destilled water in an artificial mouth **Netuschil

Oral Biofilm

Both in vitro and in vivo studies prove that combinations of CHX+CPC greater effect (Van Strydonck 2005)

Currently, lower levels of CHX (0.05%) are being used together with CPC, which improves its effect while reducing CHX’s side effects (Buscher &cols 2008)

Oral Biofilm

ADVANTAGES against planktonic bacteria

CHX ANTISEPTIC MOUTHRINSES

There are MORE AND MORE DIFFERENCES between CHX all the time

Oral Biofilm

Superior control over oral biofilm,for a better handle on gum disease.

Oral Biofilm

THE ONLY ONE THAT ACHIEVES MAXIMUM CONTROL OVER ORAL MICROBIAL LOAD

Oral Biofilm

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