Download - Automated Insulin Preparation System
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Automated Insulin Preparation System
Progress ReportGroup 22: Brant Cauthorn, Jessica Filderman, and Kellie StokaClient: Dr. Klaesner
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Product Need Prevalence
366 million people worldwide1
Cost $465 billion a year worldwide1
50% of people inject insulin wrong2
Why people do it wrong: Visual Impairment Peripheral Neuropathy Arthritis
1 Chang, Maria. The Huffington Post, 13 September 2011.2 Wartburg, Linda. Diabetes Health, 21 March 2009.
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Design Requirements General:
Small size Inexpensive Can be used in a home
setting Limited complexity
Operation: Safe Accurate Not limited by user health
conditions Room Temperature
Minimum functions: Hold two 10 ml insulin
vial(s) Mix insulin vial(s) Sterilize vial(s) Uncap needles Insert needle into vial(s) Withdraw a specified
amount of insulin
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Design Process Optional Features
Injection Capability? Temperature Control? Blood Glucose Monitor? Storage of Vials? Data Communication? Dose Verification?
Required Features User Interface Dose Vessel Mixing Sterilization Setting Dose Power Source
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Design Alternatives – Optional Features Injection Capability?
No Temperature Control?
No Blood Glucose
Monitor? No
Storage of Vials? Yes
Data Communication? Yes
Dose Verification? Yes
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Design Alternatives – User Interface
Keypad Manual “Keys”
Barcode ScannerExternal
Computer
Voice Recognition
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Design Alternatives – User Interface
User Interface Weight Keypad Manual KeysBarcode Scanner
External Computer Speech
Ease of Use 10 8 7 9 10 5 7
Reliability 8 10 10 10 9 8 5
Dose Increment 7 10 6 8 9 10 10
Range of Dose Input 7 10 6 8 9 10 10
Cost 7 7 9 7 5 10 9
Availability 6 8 9 9 10 4 10
Size 5 7 7 9 8 10 9
Total 432 386 430 433 398 418
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Design Alternatives - Mixing Conveyor Belts Drop Down Slot Vortex Vertical Arm Shaker User Mixing Tilt Shaker Horizontal Platform Shaker
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Design Alternatives - Mixing
Mixing WeightConveyer
Belts
Drop Down Slot Vortex
Arm Shaking
VerticallyUser
MixingTilting
Platform Shaker
Storage Capability 10 10 0 10 10 0 10 10
Compatability 9 9 10 8 10 10 10 10
Complexity 9 8 10 6 6 10 8 7
Accuracy 7 9 7 7 7 10 8 8
Reliability 7 9 10 7 6 9 9 8
Size 6 8 9 8 6 10 8 7
Cost 6 8 9 8 6 10 8 8
Speed 5 8 9 8 8 10 8 8
Total 515 452 460 447 483 517 495
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Design Alternatives - Sterilization Spray top of vial with isopropyl alcohol Wipe top of vial with isopropyl alcohol pad Dip top of vial in isopropyl alcohol Heat top of vial User sterilizes vial
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Sterilization Weight Spraying Wiping Dipping Heat User
Effectiveness 10 9 10 10 8 4
Reliability 10 8 8 8 6 4
Cost 9 9 8 8 8 10
Size 9 9 9 9 9 10
Complexity 8 9 9 7 7 10
Necessary Input? 8 7 6 6 10 10
Total 460 453 437 429 420
Design Alternatives - Sterilization
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Design Alternatives - Container What will hold the insulin?
Syringe Insulin Pen Cartridge Catheter
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Design Alternatives - Container
Container Weight SyringeInsulin Pen Cartridge Catheter
Cost 8 10 6 9
Pain to User 6 8 10 7
Ease of Use 10 8 9 5
Reliability 8 10 10 7
Sterility 10 10 9 6Availability 7 10 6 7
Size 5 7 9 8
Portability 6 4 10 0
Total 517 515 369
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Design Alternatives - Syringe Traditional Syringe
Significant user difficulty Modified Syringe
Moderate user difficulty New Syringe Design
Minimal user difficulty
???
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Design Alternatives - Syringe New Syringe Design
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Design Alternatives - Syringe
Syringe Type Weight Traditional Modified New
Ease of Use 10 5 7 10
Reliability 10 10 10 10
Accuracy 10 10 10 10
Cost 9 10 9 8
Size 8 10 10 10
Total 420 431 452
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Design Alternatives – Setting Dose and Drawing Up Insulin Stepper Motor Spacers Bar Pressure
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Design Alternatives – Setting Dose and Drawing Up Insulin
Setting Dose Weight Motor Spacers Bar Pressure
Accuracy 10 8 8 8 6
Two types of insulin possible? 10 10 5 10 9
Sterility 9 10 10 10 10
Reliability 8 8 8 8 6
Speed/duration 7 8 6 6 8
Complexity of design 7 8 8 8 6
Cost 6 8 5 6 8
Size 6 10 8 8 8
Total 554 460 516 482
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Design Alternatives – Dose Verification Weight
Weigh vials before and after drawing insulin Use density to determine volume change
Light Shine light through syringe, measure absorption Raise light vertically until absorption changes
(Insulin-air interface)
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Design Alternatives – Dose Verification
Dose Verification WeightWeight
Solution Light Solution
Compatibility 10 10 9
Reliability 9 5 8
Accuracy 9 8 8
Design complexity 8 8 5
Cost 7 10 9
Size 7 10 9
Total 421 400
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Chosen Design
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Next Steps Select materials and parts Determine precise assembly of parts What happens if machine malfunctions Choose convenient locations for supply input Machine waste removal
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Schedule
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Team Responsibilities Brant – Website Design and Maintenance, CAD
Drawings Kellie – Material & Manufacturing
Requirements, CAD Drawings Jessica – Risk Analysis, Report Editing
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Questions?