Download - Anat urologi
-
7/29/2019 Anat urologi
1/17
ANATOMYANATOMY
-
7/29/2019 Anat urologi
2/17
Urogenital system consists
of
- Urinary system
- Male genital system
- Female genital system
-
7/29/2019 Anat urologi
3/17
URINARY SYSTEM consists :KidneyUreterUrinary bladderUrethra
MALE GENITAL SYSTEM consists :TestisDuctuli systemAccesorius Glands
Penis
-
7/29/2019 Anat urologi
4/17
-
7/29/2019 Anat urologi
5/17
-
7/29/2019 Anat urologi
6/17
URINARY SYSTEMURINARY SYSTEM
The principal function : Filtration of most small molecules from
blood plasma Selective reabsorbtion Secretion of some excretory product
directly from blood Maintenance of acid-base balance
-
7/29/2019 Anat urologi
7/17
KIDNEYIDNEYMacroscopic:
- bean shaped organ
- retroperitoneal
- hilus medial border* nerves, blood and lymph
vessel enter/exit
* ureter exit- lateral border convex
-
7/29/2019 Anat urologi
8/17
KIDNEYIDNEYMicroscopic:
1.Cortex Renalis
- Columna Renalis
Bertini
- Medullary rays- Uriniferus tubules
2.Medulla Renalis
-Thicker twist than
cortex- Medullary Pyramids
- Collecting tubules
-
7/29/2019 Anat urologi
9/17
-
7/29/2019 Anat urologi
10/17
Kidney Functional UnitKidney Functional UnitUriniferus Tubules Each kidney 1- 4 million UT Interstitial tissue contain : Collagen fiber,blood
and lymph vessels & nerves fiberUT consist :
- Nephron:- Renal corpuscle- Proximal convoluted tubule- Loop of Henle- Distal convoluted tubule
- Collecting tubule
-
7/29/2019 Anat urologi
11/17
Structure Function
Renal corpuscle Glomerulus :Filtration of water and dissolved substances from
blood plasma Glomerular capsule: Receives glomerular filtrate
Descending limb of Reabsorption of water by osmosis the nephron loop
Ascending limb of Reabsorption of chloride ions by activetransport and passive reabsorption of sodium ions
the nephron loop Distal convoluted Reabsorption of water by osmosis tubule Reabsorption of sodium ions by active transport Active secretion of hydrogen ions Passive secretion of potassium ions by electrochemical attraction Papillary duct Passive reabsorption of water by osmosis; drains
urine from several nephrons
-
7/29/2019 Anat urologi
12/17
NephronProximal convoluted: Reabsorption of water by
osmosis
Tubule:-Reabsorption of glucose, amino acids, creatine,lactic acid, citric acid, uric acid, ascorbic acid,phosphate ions, sulfate ions,calcium ions,
potassium ions, and sodium ions by activetransport
- Reabsorption of proteins by pinocytosis
- Reabsorption of chloride ions and othernegatively charged ions by electrochemicalattraction
Active secretion of such substances as penicillin,histamine, and hydrogen ions
-
7/29/2019 Anat urologi
13/17
-
7/29/2019 Anat urologi
14/17
Function :
*reabsorbtion 80 % ultrafiltrat:
-ion Na active, diffusion from lumen into tubules cell about 65 %-water osmosis, ultrafiltrat osmolaritas no changes-glucose, protein, amino acid, acetoacetic acid & vitamin.
*excrete : creatinin, sodium anorganik, phenol red, drugs
Proximal Tubules
-
7/29/2019 Anat urologi
15/17
Loop of HenleLoop of Henle
Length depend on the location of renal corpuscle
Divided in three part- straight to medulla- arcus- straight to cortex
Function : -concentrated ultrafiltrat glomeruli
-AH descending : excretion ion Na & Cl from cell to thelumen, water enter the cell.-AH ascending :reabsorption Na & Cl ion, water out of cell
-
7/29/2019 Anat urologi
16/17
Distal TubulesDistal TubulesStraigthpart: prolonged from pars ascendens AH
-cells change from simple squamosa to simple cuboidal cell
-citoplasma asidophil,mitochondria and RE granular/smooth arounnucleus, AG apical nucleus.
-EM: interdigitasi , ZO, microvili.
Makula densa: -DT in vascular pole, micr same straightpart
- function AJGContortus part:
-micr:- cuboidal cell (5-8 cell), asidophil
- citoplasma : mitochondria oval, lisosom
-
7/29/2019 Anat urologi
17/17
Juxtaglomerular ApparatusJuxtaglomerular Apparatus
Consist :- makula densa- mesangial extraglomerular cell- juxtaglomerular cell
(modification from smooth muscular t.mediaafferen
art epitheloid cell at vascular pole)
Function :product : - renin
- eritropoetin