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Amy Huang, M.D., MHSAProgram Manager for China InitiativesUniversity of Michigan Medical School
November 1, 2011
Introduction to China Platform
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Agenda
Why China
China Platform – institution to institution collaboration
How did UMHS-PUHSC JI get started
Where are we at
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“To educate students, physicians and biomedical scholars and to provide a spectrum of comprehensive knowledge, research, patient care and service of the highest quality to the people of the state of Michigan AND BEYOND.”
University of Michigan Medical School Mission Statement
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Fall 2011 Chinese Student Enrollment
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Why China?
1080 UMHS employees holding China citizenship
19 UM Medical School Departments collaborating with 31 Chinese Universities30+ students from China currently enrolled
in our Medical School Joint Lab – Peking UniversityPopular location for medical student electives
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International Collaborations: Joint papers from UM Med School Faculty and Faculty at Foreign Medical Schools (# of papers last 5 years, based on location of first author)
U.S. not included
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“Collaborations”
Communication/exchange (email, shared discussion at a meeting)
“Visit” or “Delegation” Faculty &/or student-trainee exchange ‘Memorandum of Understanding’ Shared Research Project Shared Research Lab
Programmatic Development
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Strategic Platform =Institution-Institution Initiative
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Strategic Platform =Institution-Institution Initiative
New translational research initiatives resulting in major impact studies
A ‘brokerage’ for those wishing to partner around education and research
A mechanism to provide seed funding and to facilitate competitive funding
Outcome based education initiatives that support above
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Clinical ActivityUMHS vs. Top Four Chinese Medical School UMHS FUDAN SHJT PUMC PUHSCAffiliated Hospitals/Centers 8
10
12
6 8
Total Beds 930 7,000
12,000
4,713
6,688
Daily
Outpatient Visits: ~6,411 32,000
45,390 12,984
32,431
Emergency Room Visits: ~319 1,620 N/A N/A
1,810
Discharges ~171
730
1,112 489 762
Operations ~177
380
556 222 389
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Strategic Partner: Peking University Health Science Center
Excellent Research and Education Similar organizational structure Engaged leadership support First Clinical Research Institute in China
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Starting points for collaboration
Mutual interest in developing shared translationalresearch and education programs with a focus on:• Liver Disease• Lung Disease• Cardiovascular Disease• Core Technologies (e.g. tissue biorepository,
drug development, bioinformatics)
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What is University of Michigan hoping to achieve?
To enhance translational research capacity and productivity
To enhance a qualified workforce for basic science and clinical research
To attract excellent students To compete successfully for
grants/endowments requiring international partnership
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What is Peking University Health Science Center hoping to achieve?
To provide expertise on study design, data interpretation, publication review, etc.
To establish training programs focused on specific diseases
To build infrastructures for translational and clinical research
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Joint Institute Activities• Joint translational and clinical research• Exchange of faculty members, medical residents,
fellows, and other researchers• Exchange of students• Joint lectures and symposia• Exchange of academic information and publications• Joint determination and management of shared
intellectual property• Joint research on the science of collaboration.
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How will we measure success?
Numbers of collaborative projects Numbers of external grants for
collaborative projects Numbers of joint publications Numbers of trainees Numbers of faculty, researchers, and
students in the exchange programs
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Joint Institute Launched October 2010
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Biorepository/Bioinformatics CoreCo-lead by PUHSC & UM
IRB/Human Subject Protections Core
Co-lead by PUHSC & UM
Collaboration CoreCo-lead by
PUHSC & UM
Cardiovascular Program
Co-lead by PUHSC & UM
Liver ProgramCo-lead by PUHSC
& UM
UM-PUHSC Joint Institute for Translational and Clinical ResearchGovernance Structure
Executive BoardCo-chaired by PUHSC & UM
Executive CommitteeCo-directed by PUHSC & UM
Pulmonary Program
Co-lead by PUHSC & UM
UM PUHSC Ora Pescovitz Han Qide Steve Forrest Ke Yang Jim Woolliscroft Wu Yangfeng Steve Kunkel Wang Xian Joe Kolars Weigang Fang
Co-directors Joe Kolars Weigang Fang
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prog
ram
s
Pulm
onar
y
Card
io-
vasc
ular
Live
rcores
biorepository-biomedical informatics
institutional review board/human protection
collaboration
UM-PUHSC Joint Institute for Translational and Clinical Research
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If successful, what will the Joint Institute look like in 2015? A research trajectory resulting in high impact,
transformative, collaborative studies, on prevalent diseases
‘self sufficient’ funding from:- Chinese Government- U.S. extramural sources- Industry, Foundations, Philanthropy
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Where are we in the JI process
Six pilot grants have been approved with two others in preparation.
Joint Institutional Review Board Progress on a common mechanisms for
biomedical informatics and biorepository Successful training course and frequent
exchanges
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JI Joint Symposium and Anniversary CeremonySept 26-20, 2011, Beijing
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Thank you!