electronic supporting information10.1007/s00604-015-1499... · web viewiran. 2 department of...
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Electronic Supplementary Material
Solid phase extraction of antidepressant drugs amitriptyline and nortriptyline from plasma
samples using core-shell nanoparticles of the type Fe3O4@ZrO2@N- cetylpyridinium, and
their subsequent determination by HPLC with UV detection
Fahimeh Zare1, Mehrorang Ghaedi1,*, Ali Daneshfar2
1 Department of chemistry, Faculty of sciences, Yasouj University, Yasouj 75918-74831, Iran
2 Department of chemistry, Faculty of sciences, Ilam University, Ilam 69315-516, Iran
*Corresponding author: Tel./Fax: + 98 743 222 3048, E-mail: [email protected]
Figure (S1). FT-IR spectra of Fe3O4 ; Fe3O4@ZrO2 and Fe3O4@ZrO2@N-cetylpyridinium -
NPs.
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Figure (S2). TGA plot of Fe3O4@ZrO2@ N-cetylpyridinium -NPs.
Figure (S3). Effect of pH on magnetic hemimicelle solid phase extraction (MSPE) extraction
efficiency (n=3).
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Figure (S4). Effect of type of surfactant on MSPE extraction efficiency (n=3).
Figure (S5). Effect of amount of surfactant on MSPE extraction efficiency (n=3).
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Figure (S6). Effect of type of eluent solvent on MSPE extraction efficiency (n=3).
Figure (S7). Standardized main effect Pareto chart for the Plackett-Burman design of
screening experiment. Vertical line in the chart defines 95 % confidence level.
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Figure (S8). Response surface for the 22 central composite designs: amount of nanoparticle-
sample volume.
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Figure (S9). The optimization plot for (a) Plackett-Burman design (b) central composite design
including seven factors.