For the transfer of 100-800kgs of powder OEL of 10 microgram, and doing it for 8-10 hrs per day usually will be done in API production.For the transfer of materials care should be taken with respect to the processing of the product as well as the personnel.With respect to personnel:The personnel should be protected by double garment, goggles, cap and double gloves.With respect to the equipment:For containment facilities; equipment provided for on-line processing of the material should be used. Various types of equipment used to overcome the containment problems are:Modular containment valves:High containment valves that makes the transfer of active ingredients or chemicals between IBCs (Intermediate Bulk Containers) much easer and less expensive than has been possible in the past.

Intermediate blending equipment:

The process is completely placed in a segregated area. Glove-ports will be present to perform any type of operation outside.The entire operations will be performed such that there is no leakage of powder from the barriers to outside. Separate cleaning procedure should also be performed.

By using butterfly valves:

These are the various ways where containment can be achieved with minimum OEL.Spill Containment Pallets, Safety Cans, Spill Response Kits and Hazmat Storage Products can also be used for for the transfer of the material of heavy weights.

Sources: http://www.gea-ps.com/npsportal/cmsdoc.nsf/WebDoc/webb7sxqljhttp://www.materialhandlingproducts.com/spill-containment-pallets.htmlhttp://www.gea-ps.com/