dnds 6003: urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf ·...

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Instructor: Prof. Michael Szell @mszll Central European University, Fall Term 2018/2019 DNDS 6003: Urban networks and human mobility Class 9: Human mobility and: Epidemiology, community Oct 18, 2018 http://michael.szell.net/teaching/dnds6003 detection, urban mixing, polycentricity

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Page 1: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Instructor: Prof. Michael Szell@mszll

Central European University, Fall Term 2018/2019

DNDS 6003: Urban networks and human mobility

Class 9: Human mobility and: Epidemiology, communityOct 18, 2018

http://michael.szell.net/teaching/dnds6003

detection, urban mixing, polycentricity

Page 2: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

What will you learn today?

The importance of human mobility for epidemiology

Measuring polycentricity and its consequences

Community detection of human mobility and interactions

Page 3: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

John George Bartholomew

Page 4: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

John George Bartholomew

Page 5: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Isochronic distances became “patchy”: What happened?

Page 6: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Black death migration1347-1353

Was one of the biggest pandemics in history: 75-200 Mio. from 1331 to 1353.

Its migration followed the sea and land trading routes of the medieval world.

https://en.wikipedia.org/wiki/Black_Death_migration

Page 7: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Black death migration

Page 8: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Spread of Ebola 2014

Over 50% fatality rateNo treatment

Page 9: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Spread of Ebola 2014

Largest outbreak of Ebola, by cases and geographic extent.

The virus was mostly “contained” in West Africa, but could have easily spread worldwide

https://en.wikipedia.org/wiki/West_African_Ebola_virus_epidemic

Page 10: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Spread of Ebola 2014

Largest outbreak of Ebola, by cases and geographic extent.

The virus was mostly “contained” in West Africa, but could have easily spread worldwide

http://currents.plos.org/outbreaks/article/assessing-the-international-spreading-risk-associated-with-the-2014-west-african-ebola-outbreak/

https://en.wikipedia.org/wiki/West_African_Ebola_virus_epidemic

Page 11: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

The grid has turned into a small-world!

Page 12: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Diseases now spread through the airline network

https://flightstorome.moovellab.com/#roadsinthesky

Page 13: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Change of technology and travel behavior

https://www.youtube.com/watch?v=ECJ2DdPhMxI

2013:

Page 14: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Compartmental models

https://sineadmorris.github.io/project/the-sir-model/

Compartment models are mathematical models of infectious diseases using differential equations. The population is divided into compartments, every individual in the same compartment has the same characteristics.

The simplest one is SIR (Susceptible, Infected, Recovered)

Page 15: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

https://sineadmorris.github.io/project/the-sir-model/

daily births

Compartmental models

daily deaths daily deaths daily deaths

daily infections

daily recoveries

Page 16: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

https://sineadmorris.github.io/project/the-sir-model/

daily births

Compartmental models

daily deaths daily deaths daily deaths

daily infections

daily recoveries

Page 17: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Compartmental models without vital dynamics

daily infections

daily recoveries

Because dynamics of epidemics are much faster than the vital dynamics (birth and death), we can omit those.

Page 18: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Compartmental model of the air traffic network

Exactly same set of equations, but for n nodes in the air traffic network.

Page 19: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Compartmental model of the air traffic network

Exactly same set of equations, but for n nodes in the air traffic network.

Also, there are network flow dynamics:

Where U stands for S,I, or RWhere is the flow from place n to mwnm

Page 20: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

4069 airports, 25,453 direct connectionsFlow: 9,000,000 passengers per day

Page 21: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Compartmental model of the air traffic network

- Assume that the traffic in/out of a node is proportional to its population

- Define an effective distance (asymmetric)

Page 22: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Compartmental model of the air traffic network

Each node has then a shortest path tree:

- Assume that the traffic in/out of a node is proportional to its population

- Define an effective distance (asymmetric)

Page 23: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Compartmental model of the air traffic network

Alternative visualization:

http://science.sciencemag.org/content/342/6164/1330.full

These shortest paths are not anymore about geographic distance!

Node size: trafficNode color: degreeNode y-position: distance

Page 24: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Application to Eyafjallajökull

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069829

When the volcano broke out, 27 European airports closed (nodes removed), changing dramatically the shortest path trees worldwide

Page 25: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Application to Eyafjallajökull

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069829

Page 26: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

Application to 9/11

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069829

Page 27: DNDS 6003: Urban networks and human mobilitymichael.szell.net/downloads/class_szell2018hme.pdf · Spread of Ebola 2014 Largest outbreak of Ebola, by cases and geographic extent. The

GLEAM (Global Epidemic and Mobility Model)

http://www.gleamviz.org