dna replication replication is semi-conservative (one strand is old, one strand new) each strand...
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DNA Replication• Replication is semi-conservative (one strand
is old, one strand new)
• Each strand serves as a template (or pattern) for the new strand
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Origins of Replication
• Where DNA Replication starts
• Differs between organisms– Prokaryotes = 1 origin
of replication– Eukaryotes = many
different origins of replication
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General Process of DNA Replication
• Step 1:
– DNA Helicase separates the DNA helix
• Step 2: – DNA Polymerase III builds the new strand
of DNA
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-Nitrogenous bases are located in the cytoplasm
-They enter the nucleus through the pores in the nuclear membrane
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Thymine is added accidentally.
DNA polymerase cuts the damaged DNA.
The proper base is added.
Ligase joins the two spots.
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DNA Ligase
• DNA Ligase – Forms covalent bonds between
nucleotides to create a continuous strand of DNA
– When DNA Polymerase I edits the DNA strand, DNA Ligase attaches the bases on one side of the DNA strand together.
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DNA Replication
• Replicate the following DNA strand:
• A – G – G – C – T – T – C – A – G – T
• T – C – C – G – A – A – G – T – C - A
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