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4. Fill in the diagram of acetylcholine synthesis and neurotransmission:

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3 Question Warm-up

1. Which agents are often used in the treatment of urge incontinence?

2. What group of genes is responsible for skeletal development? (FA12 p124) (FA13 p504)

3. Which cell types are derived from the neural crest? (FA12 p126) (FA13 p505) (SU13 p44-45)

Cellular CommuniCationGG: Chapter 3, 8Phys: Chapter 45, 60R: Chapter 3

Cholinergic neurotransmission (FA12 p264) (FA13 p232) (SU13 p47) (GG p182) (Phys p731)Catecholamine synthesis (FA12 p112) (FA13 p108)Noradrenergic neurotransmission (FA12 p264) (FA13 p232) (SU13 p47)G protein second messengers (FA12 p263) (FA13 p231) (SU13 p46, 197) (Phys p548) (R p90-91) (GG p52)

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6. Fill the signal transmission pathways:

5. Fill in the diagram of norepinephrine synthesis and neurotransmission:

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end of session Quiz

7. What substances inhibit the reuptake of norepinephrine? (FA12 p264) (FA13 p232) (SU13 p47)

8. What substances stimulate the release of norepinephrine from neurons? (FA12 p264) (FA13 p232) (SU13 p47)

9. What G protein class does each of the following receptors stimulate? (FA12 p263) (FA13 p231) (SU13 p197)

• α₁• α₂• β₁• β₂• M₁• M₂• M₃• D₂

10. Outline the pathway by which stimulation of a Gs receptor activates protein kinase A. (FA12 p263) (FA13 p231) (SU13 p197) 3