discussion

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/ Stroke Cerebrovasc Dis 1994;4:594 @ 1994 National 5troke Association Discussion SESSION X Dr. Johll Moossy: What was the source of the em- bolus? Dr. De Reuck: There was certainly occlusion of the middle cerebral artery in four of the neurotropin- and four of the placebo-treated group. We did not dissect the carotidartery completelyso we cannotsay, but we had generalautopsy. Wealso had cardiac eval- uation postmortem that excluded, in our view, cardiac sources. Dr. James F. Toole: I need to know, once again, what neurotropin is. I missed that point. How do you give it? Dr. De Reuck: You give it intravenously. Dr. Toole: Is it a diuretic? Dr. DeReuck: No, it is on the market in Japan. It is a biological extract and that is the main problem. It is not specifically for edema; it is an anti-inflammatory drug, but it has an effect as it blocks the kinin. It has been tried in brain edema and has been shown to have effect. 594 J STROKE CEREBROVASC DIS, VOL. 4, SUPPLEMENT 1, 1994

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/ Stroke Cerebrovasc Dis 1994;4:594@ 1994 National 5troke Association

Discussion

SESSION X

Dr. Johll Moossy: What was the source of the em­bolus?

Dr. De Reuck: There was certainly occlusion of themiddle cerebral artery in four of the neurotropin­and four of the placebo-treated group. We did notdissect the carotid artery completely so we cannot say,but we had general autopsy. We also had cardiac eval­uation postmortem that excluded, in our view, cardiacsources.

Dr.James F. Toole: I need to know, once again, what

neurotropin is. I missed that point. How do you giveit?

Dr. De Reuck: You give it intravenously.Dr. Toole: Is it a diuretic?Dr. DeReuck: No, it is on the market in Japan. It is a

biological extract and that is the main problem. It isnot specifically for edema; it is an anti-inflammatorydrug, but it has an effect as it blocks the kinin. It hasbeen tried in brain edema and has been shown to haveeffect.

594 JSTROKECEREBROVASC DIS, VOL. 4, SUPPLEMENT 1, 1994