ASIAN NETWORK OF ASIAN NETWORK OF RESEARCH ON RESEARCH ON

ANTIANTI--DIABETIC PLANTS (ANRAP)DIABETIC PLANTS (ANRAP)

99tthhINTERNATIONAL SEMINAR INTERNATIONAL SEMINAR

FROM PLANT TO PATIENT: FROM PLANT TO PATIENT: IDENTIFICATION OF NEW DRUGS IDENTIFICATION OF NEW DRUGS

FOR METABOLIC DISORDERSFOR METABOLIC DISORDERS

January 25 January 25 -- 27, 201927, 2019

Organizedby:

DR.PANJWANICENTERFORMOLECULARMEDICINEANDDRUGRESEARCH,

INTERNATIONALCENTERFORCHEMICALANDBIOLOGICALSCIENCES(ICCBS),UNIVERSITYOFKARACHI,KARACHI-75270,PAKISTAN

INVITATION Dear Colleagues,

It is a great honor and pleasure to invite you to the 9th ANRAP International Seminar on “From Plant to Patient: Identification of New Drugs for Metabolic Disorders” which will be held at the Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan, during January 25-27, 2019.

In recent years there is a rapid increase in the metabolic disorders, challenging the available therapeutics to control their global spread. The medicinal value of Asian plants has been known since centuries but proper measures to harness their potential are still in infancy. The discovery of artemisinin for malaria, and metformin for diabetes are prime examples of therapeutic potential of plant derived compounds. Natural products are an important source of new drugs in all major disease areas, including metabolic disorders. ANRAP (Asian Network of Research on Anti-Diabetic Plants) was established with the aim of coordinating research efforts in the field of antidiabetic plant materials with enormous floral resources of the Asian subcontinent. With the vision to provide a common platform to the scientists working for elucidating the therapeutic potential of plants against metabolic disorders, ANRAP is organizing international and national seminars, workshops and symposia in the relevant fields since 1994. The previous ANRAP International Seminars were held in Bangladesh (Dhaka), India (Kolkata), Nepal (Kathmandu), and Malaysia (Kuala Lampur). The 9th meeting of this series is scheduled during January 25-27, 2019 in Karachi, Pakistan. ANRAP-9 will provide an opportunity to bring world famous scientists in the multidisciplinary fields of metabolic disorders together and exchange ideas and views on different themes. This will foster cross-breeding of ideas and developing a common strategy towards the science-based development of plant-based medicine against diabetes, and other metabolic disorders. Along with this, it will indeed be an opportunity to learn about rich and diverse culture of Pakistan.

We are looking forward to see you in Karachi.

Prof. Dr. M. Mosihuzzaman Chairman, ANRAP Board

Prof. Dr. M. Iqbal Choudhary, H.I., S.I., T.I. Director, ICCBS/ Chairman ANRAP-9

VENUE The seminar will be held at the beautiful campus of International Center for Chemical and Biological Sciences (ICCBS) at the University of Karachi. The ICCBS campus is located at about 20 minutes drive from the Jinnah International Airport and about 40 minutes driving distance from the largest shopping area in the center of the city. Bank, post office, stores, restaurants, malls and travel agencies are also located within short distance of the seminar venue. Evening bus shuttles will run for the participants, staying on-campus, to take them to various shopping centers and other attractions in the city.

AIMS AND OBJECTIVES § To bring the national and international researchers

together, particularly from the Asian region, to share knowledge, exchange ideas and research experiences in combating metabolic disorders and other related diseases. Most importantly this major event will expose young Pakistani researchers with the best of science and technologies in the world in the exciting field of natural product chemistry and pharmacology, as well as contribution of natural products in modern drug discovery and development.

§ To emphasize the importance of strengthening R&D capacity and capabilities in addressing the needs of our nation and other Asian countries.

§ To raise awareness on the development and frontier research towards paving the way forward in the fight against metabolic disorders, and other related diseases.

§ To coordinate the efforts of a diverse group of scientists, chemists, microbiologists, molecular biologists, pharmacists, and experts in analytics, such as NMR spectroscopy and mass spectrometry to constitute a platform for research networking and creating links for future collaborations.

SCOPE § Ethnopharmacology of antidiabetic medicinal plants. § Natural products for the management of metabolic

disorders.

§ Research study on complications associated with metabolic disorders and other related diseases.

§ Discovery of lead molecules from medicinal plants for the management of metabolic disorders.

§ Development of new drugs from the regional biota for the management of metabolic disorders.

§ Standardization, efficacy and safety of herbal remedies.

§ Best strategies for pre-clinical studies, and clinical trials in plant-based formulations.

CALL FOR PAPERS / POSTERS All participants are invited to present their research in the form of oral and poster presentations. Abstracts for oral and/or poster presentations should be sent to anrap2019@gmail.com or raheelhej@gmail.com by December 15, 2018. The poster board area will be 1.2 m x 1.8 m.

REGISTRATION

Registration Fee: Before After (Foreign Participants) Nov. 15, 2018

(U.S. $) Nov. 15, 2018

(U.S. $) Private organization 300 350 Academic faculty 150 200 Student 100 150 Accompanying person 100 150

Registration Fee: Before After (Pakistani Participants) Nov. 15, 2018

(Rs.) Nov. 15, 2018

(Rs.) Private organization 10,000 15,000 Academic faculty 8,000 10,000 Student 4,000 5,000 Accompanying person 3,000 3,000

DEADLINES TO MEET

ANRAP-2019 January 25 – 27, 2019 Advance Registration November 15, 2018 Accommodation Request December 15, 2018 Abstract Submission December 15, 2018 Tour Reservations December 15, 2018

In the case of cancellation before December 1, 2018, the fees will be refunded after a 50% deduction. No refund on cancellation will be made after this date. A 20% discount will be given to ANRAP members. ANRAP membership forms are available with Dr. Hafizur Rahman (as well as on ANRAP website: www.anrap.org)

ACCOMMODATION All plenary and invited speakers will be accommodated in the International Guest Houses of ICCBS, which has excellent housing facilities. However other participants can reserve their accommodation from the following hotels in advance, on self-payment basis. Complementary transportation will be provided to them during the symposium.

Class A Approx. per night

Distance from the venue 5-3 Star Hotels

A-1 Movinpick US$ 300 (20 kms) A-2 Marriott US$ 300 (20 kms) A-3 Pearl Continental US$ 300 (20 kms) A-4 Avari Tower US$ 300 (18 kms) A-5 Regent Plaza US$ 150 (16 kms) A-6 Carlton US$ 200 (25 kms) A-7 Ramada Inn US$ 200 (6 kms)

Class B (Other Hotels)

C-2 Best Western Hotel US$ 80 (13 km) C-3 Hotel Mehran US$ 70 (15 km) C-3 Embassy Hotel US$ 60 (14 km)

Class C (Only for foreign graduate students)

Guest Houses US$ 35 (10-15 km)

LANGUAGE

The official language of the conference will be English.

VISA

You are requested to apply for a visa to the nearest Pakistani Embassy or High Commission. Participants from countries with no Pakistani diplomatic mission should also write to the Secretariat at least four months in advance. A formal invitation letter would be required from the Chairman, Organizing Committee (Prof. Dr. M. Iqbal Choudhary) for this purpose.

FOREIGN CURRENCY Registration fee at the symposium desk can be paid in cash or through checks. Currency conversion to Pakistani Rupees will be available upon request.

CLIMATE

Karachi is usually sunny and pleasant in January with average day temperature of 20°C and the night temperature falling to 11-14°C. Winters from November to February have chilly nights and bright sunny days.

TRAVEL Karachi has a modern international airport, which provides connections to all major cities of the world. Most of the major airlines of the world have frequent flights to Karachi, since the city provides a major route linking with the Far East as well as with the Middle East, Europe, and USA. Pakistan International Airlines (PIA) is the national flag career. Your travel agent or any PIA office can provide you with full details on travel to Karachi.

PAKISTAN’S BASIC FACTS Area 8,03943 sq. km Population 207 million Capital Islamabad Provinces Capital Cities

Sindh Karachi Balochistan Quetta Punjab Lahore Khyber Pakhtoonkhwah (KPK) Peshawar Gilgit Baltistan Gilgit Azad Jammu & Kashmir Muzaffarabad (autonomous region) Principal Cities: Karachi, Lahore, Hyderabad, Peshawar, Sukkur, Quetta, Multan, Bahawalpur, Faisalabad, Sialkot, Gujranwala, Rawalpindi, Islamabad. Hill Resorts: Swat, Murree, Nathiagali, Abbottabad, Kaghan.

Languages:

National Language is Urdu. English is widely used in correspondence and communication. Punjabi, Sindhi, Pashtu, Baluchi and Bilti are the principal regional languages.

SHOPPING The cities of Pakistan rightly boast of rich oriental bazaars as well as modern shopping plazas. Bargaining is not uncommon in the market places. Leather, woolen, cotton, brass, copper, wood and gold works are some of the specialties. Onyx ware is in abundance. Gold and silver jewellery, intricately handcrafted, is also a major attraction. Pakistani carpets and rugs are among the best in the world.

PAKISTANI CUISINES Pakistani food is rich and generally meat based. All restaurants offer a range of “Kababs”, barbecued chicken and grilled meat variously spiced and marinated. The most popular meat is chicken followed by lamb. Beef kababs are also popular. Flattened bread (“nan”) baked in a deep gas or coal-fired or thinner floppy bread (“chapati”) pit is invariably served with all meals. If you like curry, there is a whole variety available everywhere. The popular local drinks are “lassi” (yogurt beaten to a rich paste with water and sugar added) or fresh lime in water sweetened with a rich helping of sugar. The food is not expensive. However take care and avoid drinking unboiled tap water or raw vegetables.

TOUR AND SIGHTSEEING TRIPS Several tours and sightseeing trips have been arranged for the conference participants and accompanying persons. This program covers guided tours to Karachi City, visits to beaches outside Karachi, archeological sites, and to the ancient and new cities of Pakistan.

FOR CORRESPONDENCE ORGANIZING SECRETARY, ANRAP-9 International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Karachi-75270, Pakistan Tel: +92 (21) 34824934, 34824930 Fax: +92 (21) 99261713, 34819018 E-mails: anrap2019@gmail.com; raheelhej@gmail.com

ORGANIZING COMMITTEE Prof. Dr. Atta-ur-Rahman, FRS, N.I., H.I., S.I., T.I. Patron-in-Chief

Prof. Dr. M. Iqbal Choudhary, H.I., S.I., T.I. Director, ICCBS/ Chairman ANRAP-9

Dr. Asmat Salim Organizing Secretary

Dr. Md. Hafizur Rahman Seminar Coordinator

MEMBERS Prof. Dr. Viqar U. Ahmed, H.I., S.I. Prof. Dr. Bina S. Siddiqui S.I., T.I. Prof. Dr. Shaheen Faizi, S.I. Prof. Dr. Sabira Begum, P.P. Prof. Dr. Muhammad Shaiq Ali, T.I. Prof. Dr. Khalid M. Khan, T.I., S.I. Prof. Dr. Zafar Saied Saify Prof. Dr. Fatima Basha, S.I. Prof. Dr. Darakhshan J. Haleem Prof. Dr. M. Iqbal Bhanger, P.P. Prof. Dr. Muhammad Arfan Prof. Dr. Farzana Shaheen Prof. Dr. Syed Abid Ali Prof. Dr. M. Raza Shah, T.I.

Prof. Dr. Syed Ghulam Musharraf Dr. Shabana U. Simjee Dr. Zaheer-ul-haq Qasmi Dr. Maqsood A. Chotani Dr. Sammer Yousuf Dr. Shakil Ahmad Dr. Atia-tul-Wahab Dr. Muhammad Imran Malik Dr. Hina Siddiqui Dr. Reaz Uddin Dr. Ishtiaq Ahmed Khan Dr. Abdul Hameed Dr. Syed Tarique Moin Dr. Humera Jahan Dr. Sadia Ajaz Dr. Sobia Rana Dr. Ghulam Abbas Dr. Almas Jabeen

Dr. Munazza Raza Dr. Irfan Khan Dr. Ghulam Mustafa Dr. Ayaz Ahmed Dr. Naghma Hashmi Dr. Saima Rasheed Dr. Mudassar Azhar Dr. Mujeeb-ur-Rehman Dr. Malik Shoaib Ahmad Dr. Arslan Ali Dr. Sumaira Javed Dr. Maria A. Khan Dr. Syeda Rehana Zia Dr. Asma Rauf Dr. Humaira Zafar Dr. Naghma Naz Dr. Rana Zeeshan Haider Dr. Salman Ahmed Khan Dr. Sayed Ali Raza Shah Dr. Ambrina Khatoon Dr. Ghayas Uddin Siddiqui Dr. Zarrin Basharat Dr. Muhammad Irfan Dr. Muhammad Shakeel Dr. Asad Karim Alvi Dr. Muhammad Rashid

Management Mr. Raheel Baig Mr. Javed Riaz Mr. Mahboob Alam Ms. Ferheen Khan

ANRAP Board: Chairman Prof. Dr. Mohammed Mosihuzzaman Bangladesh

General Secretary Prof. Dr. Begum Rokeya Bangladesh

Members Prof. Dr. M. Iqbal Choudhary Pakistan Prof. Dr. Khozirah Shaari Malaysia Prof. Dr. Banasri Hazra India