discover stem cells. by the end of this lesson, you should… know what a stem cell is know about...
TRANSCRIPT
Discover stem cells
By the end of this lesson, you should…
Know what a stem cell is
Know about different types of stem cellsand where they are
Know why stem cells are important
What we’re going to do today
Stem cell decision maker – in groups
Talk more about stem cells
Types of stem cells – in groups
Summary
Your feedback
What stem cells can do
Use the decision maker to find out
What’s under the flap?• Stem cell take another blood stem cell
• Any other cell put your blood stem cell in the cup with that cell type on it
You can only play if you still have a stem cell token!
What is a stem cell?
1 stem cell
Self renewal – makes sure stem cells don’t run out
Why self-renew AND differentiate?1 stem cell
4 specialized cells
Differentiation - replaces dead or damagedcells throughout your life
Stem cells in your body = Tissue stem cellssurface of the eye brain
skin breast
muscles intestines (gut)
bone marrow
Blood stem cells: A type of tissue stem cell
blood stem cell
found in bone marrow
differentiation
only specialized types of blood cell
white blood cells
red blood cells
The blood challenge
How hard do your blood stem cells work?
Let’s find out!
Blood stem cells have a big job!
If you lined up all the red blood cells from your body, how far would they stretch?
Nearly 4 times around the earth’s equator
Image by Beeblebrox
How long does it take your body to make 2 million red blood cells?
How quickly can youcount to 2 million?
Making red blood cells
Making red blood cellsWe counted to 20 in…
To count to 2 millionit would take…
2 seconds
3 seconds
4 seconds
5 seconds
6 seconds
Making red blood cellsWe counted to 20 in…
To count to 2 millionit would take…
2 days2 seconds
3 seconds
4 seconds
5 seconds
6 seconds
Making red blood cellsWe counted to 20 in…
To count to 2 millionit would take…
3 days
2 seconds
3 seconds
4 seconds
5 seconds
6 seconds
Making red blood cellsWe counted to 20 in…
To count to 2 millionit would take…
5 days
2 seconds
3 seconds
4 seconds
5 seconds
6 seconds
Making red blood cellsWe counted to 20 in…
To count to 2 millionit would take…
6 days
2 seconds
3 seconds
4 seconds
5 seconds
6 seconds
Making red blood cellsWe counted to 20 in…
To count to 2 millionit would take…
7 days
2 seconds
3 seconds
4 seconds
5 seconds
6 seconds
To make 2 million red bloodcells it takes your body…
Making red blood cellsWe counted to 20 in…
To count to 2 millionit would take…
2 days
5 days
6 days
7 days
3 days
1 second!
2 seconds
3 seconds
4 seconds
5 seconds
6 seconds
Your body is more than just blood!
• Shuffle and deal the cards face down.
• The player to the left of the dealer starts.
• On your turn, choose a card you don’t want and give it to the person on your left.
• When you are given a new card: If you’ve got a family of 4, put it down on the table for everyone to see. Then choose a card to give to the person on your left.
• Keep going until the cards are used up.
Stem cells in your body
Keep it moving! You only have a short time to play. Can your group be the first to get all the families?
Cell families
Where are the stem cells in your body?
Stem cells in your body
embryonic stem cells
skin
liver
neurons
ES cells can make many kinds of specialised cells in the lab!
Embryonic stem cells
What we’ve learnt today
Stem cells can:• Self-renew = copy themselves• Differentiate = make other types of cell
There are different kinds of stem cell:• Tissue stem cells – in our bodies all our lives
– only make particular cell types• Embryonic stem cells – in the early embryo
– can make all the cells of the body
We need stem cells to…• Replace cells that die or get damaged• In the future, we might use them to treat diseases or test drugs