diploma in pharmacy (second year) pharmaceutics-ii … · 27 .09.18 types of ointments-according to...

21
DIPLOMA IN PHARMACY (SECOND YEAR) SUBJECT : PHARMACEUTICS-II (2131) SUBJECT TEACHER : Sh. SHIV KUMAR TOTAL HOURS ASSIGNED : Theory: 75 Hours (3 Hours/week), Practical: 75 Hours (Total 6 Hours/Week, 3 Hours/Week per Batch) Unit/ Title of Hours Date Theory Topic Practical Practical Topic Chapter Unit/Chapter Allotted Day Day 3 03.07.18 1 Reading & understanding of prescription, 1,2 Introduction to Pharmaceutics –II laboratory work Prescription 05.07.1 8 2 Latin terms commonly used, method of prescribing, To understand Prescription & Latin terms used in 06.07.18 3 Adaptation of metric system & calculation prescription 10.07.18 Study of various type of Incompatibility- introduction & 4 4 importance of Incompatibility in stability of various dosage 3,4 forms Classification of Dosage form & Coding of experiments Incompatibility 12.07.18 5 Physical Incompatibility- Introduction, cause & correction based on dosage forms method. To understand Weights & Measures involved in dispensing in Prescriptions 1 13.07.18 6 Chemical Incompatibility- Introduction, cause & correction method. 17.07.18 7 Therapeutic Incompatibility-- Introduction, cause & correction method. 5,6 Classification of Dosage form & Coding of experiments 19.07.18 8 Dose based on dosage forms Factor influencing of dosage calculation- age, sex, disease 20.07.18 Dosage calculation 9 state, body weight, day &night etc. Posology 3 24.07.18 10 Calculation of dosage for child- according to Young’s, Clark 7,8 To prepare & submit Simple Mixture containing Ferric Dilling formula Ammonium citrate 2(I) Powder 11 Types of powder, advantage & disadvantage of powders To prepare & submit Simple Mixture containing Acetyl 26.07.18 Salicylic Acid. 27.07.18 12 Cachets & Tablet Triturate. 02.08.1 8 13 Preparation of different type of powders encountered in 9,10 To prepare & submit Simple Mixture containing prescription Ammonium Chloride. 03.08.18 Weighing method – Analytical Balance, Dispensing Balance 14 To prepare & submit Mixture containing Diffusible solids. 7 & Digital Balance 07.08.18 15 Possible errors on weighing, minimum weighable amount 09.08.18 Powder mixing technique –Trituration, Spatulation 11,12 16 Geometric dilution To prepare & submit Mixture Indiffusible Solids. To prepare & submit Mixture Slightly soluble liquids. 10.08.18 17 Proper usage & care of Dispensing balance Lesson Plan for Pharmaceutics-II (2131) (Session 2018-19) |

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DIPLOMA IN PHARMACY (SECOND YEAR)

SUBJECT : PHARMACEUTICS-II (2131)

SUBJECT TEACHER : Sh. SHIV KUMAR

TOTAL HOURS ASSIGNED : Theory: 75 Hours (3 Hours/week), Practical: 75 Hours (Total 6 Hours/Week, 3 Hours/Week per Batch)

Unit/ Title of Hours Date

Theory Topic

Practical Practical Topic

Chapter Unit/Chapter Allotted Day Day

3

03.07.18 1 Reading & understanding of prescription, 1,2 Introduction to Pharmaceutics –II laboratory work

Prescription 05.07.18 2 Latin terms commonly used, method of prescribing, To understand Prescription & Latin terms used in

06.07.18 3 Adaptation of metric system & calculation prescription

10.07.18

Study of various type of Incompatibility- introduction &

4

4 importance of Incompatibility in stability of various dosage 3,4

forms Classification of Dosage form & Coding of experiments

Incompatibility

12.07.18 5

Physical Incompatibility- Introduction, cause & correction based on dosage forms

method.

To understand Weights & Measures involved in dispensing

in Prescriptions

1 13.07.18

6 Chemical Incompatibility- Introduction, cause & correction

method.

17.07.18 7

Therapeutic Incompatibility-- Introduction, cause &

correction method. 5,6

Classification of Dosage form & Coding of experiments

19.07.18

8

Dose

based on dosage forms

Factor influencing of dosage calculation- age, sex, disease

20.07.18 Dosage calculation

9

state, body weight, day &night etc.

Posology 3

24.07.18 10

Calculation of dosage for child- according to Young’s, Clark 7,8 To prepare & submit Simple Mixture containing Ferric

Dilling formula

Ammonium citrate

2(I) Powder

11

Types of powder, advantage & disadvantage of powders

To prepare & submit Simple Mixture containing Acetyl

26.07.18 Salicylic Acid.

27.07.18 12 Cachets & Tablet Triturate.

02.08.18

13 Preparation of different type of powders encountered in 9,10

To prepare & submit Simple Mixture containing

prescription

Ammonium Chloride.

03.08.18

Weighing method – Analytical Balance, Dispensing Balance

14 To prepare & submit Mixture containing Diffusible solids.

7

& Digital Balance

07.08.18 15 Possible errors on weighing, minimum weighable amount

09.08.18 Powder mixing technique –Trituration, Spatulation 11,12

16 Geometric dilution To prepare & submit Mixture Indiffusible Solids.

To prepare & submit Mixture Slightly soluble liquids.

10.08.18 17

Proper usage & care of Dispensing balance

Lesson Plan for Pharmaceutics-II (2131) (Session 2018-19) |

2(II)-a

6

14.08.18 18

Monophasic- theoretical consideration, advantage &

disadvantage of monophasic dosage form

16.08.18 19 Aspects including commonly used Vehicles To prepare & submit mixture containing small dose of

Liquid oral 17.08.18

Essential adjuvants- Stablizers, Colourants & Flavouring

20 Potent Medicament.

dosage form- agents with example. 13,14

To prepare & submit Simple syrup.

monophasic 21.08.18

21 Reviewing of the following monophasic liquids with

detailes of formulation & practical method- Mixture

23.08.18 22 Syrup- introduction & preparation of Syrup To prepare & submit Codeine Linctus B.P.

24.08.18 23 Preparation of Linctus, Lotion Eye Drop & Ear drop

15,16 To prepare & submit Throat paint.

2(II)-b 28.08.18

24 Suspension- Introduction , advantage & disadvantage of

(I) suspension

30.08.18 25

Suspension containing diffusible solids & liquids & their 17,18 To prepare & submit Mandl’s paint.

preparation

To prepare & submit Castor oil emulsion by Dry Gum

31.08.18

26 Study of adjuvants used like Thickening agents, Wetting method.

agents their necessity & quantity to be incorporated.

Biphasic liquid

04.09.18

27

Suspension of precipitate forming liquids like tincture, their 19,20 To prepare & submit Castor oil emulsion by Wet Gum

dosage form- 7

preparation & stability. method.

(Suspension )

06.09.18 28 Suspension produced by chemical reaction To identify the given emulsion by using Dilution method.

07.09.18 29 Introduction to flocculated/ non flocculated suspension.

11.09.18 Evaluation of suspension- Sedimentation method, Rheology To identify the given emulsion by using Conductivity

30

& Micromeritics Study. 21,22 method. To prepare & submit Turpentine oil emulsion by Dry Gum

method.

13.09.18 Emulsion – type of emulsion oil in water, water in oil & 23,24

31 multiple emulsion

To prepare & submit Turpentine oil emulsion by Wet Gum

14.09.18 Identification of emulsion system- Dye test, Conductivity method.

32

test Fluorescence test To prepare & submit liquid Paraffin emulsion by Dry Gum method.

Biphasic liquid

2(II)-b 18.09.18

33 Formulation of emulsion- Dry gum method, Wet gum

dosage form- 6

(II) method Bottle method & Others

(Emulsion)

20.09.18 Selection of emulsifying agents-Natural, Semisynthetic 25,26 To prepare & submit Liquid Paraffin emulsion by wet gum

34 Synthetic, Inorganic & Alcohol method.

To prepare & submit Calamine lotion.

21.09.18 35

Instability in Emulsion-Cracking, Creaming & Phase 27,28 To prepare & submit Sulphur lotion.

Inversion

To prepare & submit Simple Ointment as per I.P.

25.09.18

36 Preservation of Emulsion- Containers, Labeling, Storage.

Lesson Plan for Pharmaceutics-II (2131) (Session 2018-19) |

27.09.18 Types of ointments-according to therapeutic properties

6

37 basis & therapeutic use.

28.09.18 Classification & selection of dermatological vehicles- 29,30

38 Oleaginous base, Absorption bases, Emulsion bases & Water

Semisolid

soluble bases To prepare & submit Sulphur Ointment as per B.P.

04.10.18 39

Preparation and stability of ointments by following process- To prepare & submit Zinc oxide ointment as per B.P.

2(III)-a dosage form-

Trituration method

(Ointments)

05.10.18

40 Preparation and stability of ointments by following process-

Fusion method

09.10.18 41

Preparation and stability of ointments by following process- 31,32 Chemical reaction method To prepare & submit Methyl Salicylate ointment as per B.P.

11.10.18 42

Preparation and stability of ointments by following process- To prepare & submit Paraffin ointment as per B.P.

Emulsification method

12.10.18 43 Difference between ointments & paste.

Semisolid 16.10.18 44

Bases of paste- Hydrocarbon bases, Water miscible bases & To prepare & submit emulsifying ointment as per B.P.

2(III)-b dosage form- 4 Water soluble bases 33,34

To prepare & submit staining ointment as per B.P.

(Paste)

19.10.18 45 Preparation of paste –Trituration method, Fusion method

23.10.18 46 Preservation of paste- Containers, Labeling, Storage.

2(III)-c Semisolid 25.10.1

8 47

Introduction of jellies- advantage & disadvantage of jellies 35,36

dosage form-

To prepare & submit non-staining ointment as per B.P.

(Jellies) 26.10.18 Different type of- medicated jellies, lubricating jellies &

48 To prepare & submit Zinc oxide and Salicylate paste B.P.

4 micellanious jellies

30.10.18 49

Formulation of jellies- gelling agent (targacanth, sodium alginate, pectine, starch gelatin, & cellulose derivative)

2.11.18 50 Preparation & preservation of jellies 37,38 To prepare & submit Unna’s paste.

Semisolid

6.11.18 51 Poultices- Introduction

To prepare & submit Glycerol suppository B.P.

2(III)-d dosage form- 2 8.11.18

52 Storage of poultice

(Poultics)

13.11.18 53 Suppositories & pessaries- their relative merits & demerits

15.11.18 Types of suppositories- Rectal, Vaginal, Nasal, uretheral & 39,40 To prepare & submit suppository containing soluble solids

54 Ear cones B.P.

Semisolid To prepare & submit suppository of Cocoa Butter

2(III)-e dosage form-

5 16.11.18 Suppositories bases classification properties – Fatty bases, containing soluble liquids.

(Suppositories & 55 Water soluble & Water miscible bases, Emulsifying bases

Pessaries)

20.11.18 Preparation-Rolling method, Hot process & Fusion method, 41,42 To prepare & submit suppository of Cocoa Butter

56 Cold compression method containing insoluble liquids.

To prepare & submit simple powder.

Lesson Plan for Pharmaceutics-II (2131) (Session 2018-19) |

20.11.18 Packing of suppositories & use of suppositories for drug 57 absorption

To prepare & submit compound powders

22.11.18 58

Introduction to Dentifrices & cosmetics, classification of

dental products.

27.11.18 59

Facial cosmetics-face powders, compact face powder, rouges

43,44

Dental and

29.11.18 60

Facial cosmetics- cold creams, cleansing creams, vanishing To prepare & submit Cosmetic Preparations

2(IV) Cosmetic 6 creams.

Preparations

30.11.18 61

Deodorants, Antiperspirants- Introduction, characteristics, Preparation

4.12.18 62 Shampoos, Hair dressings and To prepare & submit Cosmetic Preparations

6.12.18 63

Hair removers- Hair removing methods, Formulation of 45,46

Depilatory

2(V) Sterile Dosage 7.12.18 64

Parenteral dosage forms- Definition, general requirements Forms : for parenteral dosage forms. 47,48

Parenteral 11.12.18 65 Types of parenteral formulations, To prepare & submit Tooth powder

dosage forms

13.12.18

14.12.18

Vehicles, adjuvants-solublizing agents, stabilizing agents,

66 buffering agents, antibacterial, chelating agents,

suspending, emulsifying agents& wetting agents

7 18.12.18

20.12.18

21.12.18

Processing, personnel- cleansing of containers, collection of 49,50

67 material, preparation of parenteral products, filtration,

filling, sealing the containers & sterilization. To prepare & submit Insufflations

68 Facilities and quality control- Sterility test, Clarity test,

Leakage test, Pyrogen test etc.

69 Preparation of intravenous fluids and admixtures-

70 Total Parenteral nutrition, dialysis fluids 51,52

71

Ophthalmic Products- introduction like Eye-drops, Eye- lotions, Eye-ointments, Eye-suspension To prepare & submit Dusting powder

72 Study of essential characteristics of different ophthalmic

Sterile Dosage preparation- Foreign particles, Viscocity, Tonicity,

2(V) Forms :

5 73 ph of the preparation, Sterility & Surface activity 53,54

To prepare & submit Boric acid containing 1% of Iodine.

Ophthalmic 74

Formulation additives- thickening agents, buffers,

Products

antioxidants, wetting agents, isotonicity adjustment

Special precautions in handling and storage of ophthalmic 55,56 To prepare & submit compound Magnesium Trisilicate

75 products, Preparation of Eye-drops, Eye- lotion, Eye- oral powder.

ointment

Lesson Plan for Pharmaceutics-II (2131) (Session 2018-19) |

References:

1. Cooper’s & Gunn Dispensing Pharmacy 2. Industrial Pharmacy Lachmann & Libermann 3. Pharmaceutics – II, R, M. Mehta

DIPLOMA IN PHARMACY (SECOND YEAR)

SUBJECT : PHARMACEUTICAL CHEMISTRY-I I(2132)

SUBJECT TEACHER : DALBIR SINGH

TOTAL HOURS ASSIGNED : Theory: 100 Hours (4 Hours/week), Practical: 75 Hours (Total 6 Hours/Week, 3 Hours/Week per Batch)

Unit/ Title of Hours Date Topic Practical Topic

Chapter Unit/Chapter Allotted

2.07.18 Introduction to the nomenclature of organic chemical systems- nitrogen

Introduction to containing heterocyclic compound

1 the nomenclature 3 3.07.18 Introduction to the nomenclature of organic chemical systems- sulphur To introduce Pharmachem –II laboratory of organic containing heterocyclic compound

chemical systems 4.07.18 Introduction to the nomenclature of organic chemical systems- oxygen

containing heterocyclic compound

The chemistry of following Pharmaceutical organic compounds, covering their nomenclature, chemical structure, uses and important physical and chemical properties (Chemical structure

of only those compounds marked with asterisk (*).

The stability and storage conditions and the different type of pharmaceutical formulations of these drugs and their popular brand names.

6.07.18 Antiseptics and Disinfectants – Proflawine, Benzal-koniumchloride,

3.1 Antiseptics and

3 Cetrimide, Chlorocresol*, Chloroxylene, Formaldehyde solution,

Disinfectants 9.07.18

10.07.18 Hexachlorophene liquefied phenol, Nitrofurantoin. To determine the Melting point of the given solid organic

compound

11.07.18 Sulfonamides- Sulfadiazine, Sulfa guanidine.

3.2 Sulfonamides 3 13.07.18 Phthaysulfathiazole, Sulfamethoxypyridazine, To determine the Boiling point of the given liquid organic

compound.

16.07.18

17.07.18 Sulfamethoxazole, co- trimoxazole, Sulfacetamide. To identify the given organic drug (sample D-1) by

18.07.18 20.07.18

Antiteprotic Drugs- Clofazimine,

Antiteprotic

systematic qualitative analysis

3.3 3 Thaimbatosine, Dapsone,

Drugs

23.07.18

Solapsone.

24.07.18 Anti-tubercular Drugs- Isoniazid, PAS To identify the given organic drug (sample D -2) by

Anti-tubercular

systematic qualitative analysis.

3.4 3 25.07.18 Streptomycin, Rifampicin, Ethambutal,Thiacctazone

Drugs

27.07.18 Ethionamide, Cycloscrine, Pyrazinamide.

Antiamoebie and 30.07.18 Antiamoebie and Anthelmintic Drugs- Emetine, Metronidazole, To identify the given organic drug (sample D -3) by

3.5 Anthelmintic 3

Halogenated Hydroxyquinolines, Diloxanidefuroate, Paramomycin Piper systematic qualitative analysis

1.08.18

Drugs

Lesson Plan for PHARMACEUTICAL CHEMISTRY-II (2132) (Session 2018-19) |

1.08.18 zinc, Mebendazole, D.E.C. To identify the given organic drug (sample D -4) by

systematic qualitative analysis

3.08.18

Antibiotics- Benzyl Penicillin, Phenoxy Methyl,

6.08.18 Penciline, Benzathine Penicillin, Ampicilin,

3.6 Antibiotics 5 7.08.18 Cloxacillin, Carbenicillin, Gentamicin, Neomycin,

8.08.18 Erythromycin, Tetracycline, Cepahalexin, Cephaaloridine, To identify the given organic drug (sample D -5) by

10.08.18

Cephalothin, Griseofulvine, Chloramphenicol. systematic qualitative analysis

3

13.08.18 Antifungal agents- Undeeylenic acid,

3.7 Antifungal agents 14.08.18 Tolnaftate, Nystain,

17.08.18 Amphotericin, Hamyein. To identify the given organic drug (sample D -6) by

Antimalarial

20.08.18 Antimalarial Drugs- Chloroquine*, Amodiaquine, systematic qualitative analysis.

3.8 3 21.08.18 Primaquine, Proguanil,

Drugs

24.08.18

Pyrimethamine*, Quinine, Trimethoprim.

27.08.18 Tranquilizers- Chlorpromazine*, Prochtorperazine, Trifluoperazine, To identify the given organic drug (sample D -7) by

3.8 Tranquilizers 3 28.08.18 Haloperidol, Tripe idol, Oxypertine, Chlordiazepoxide, systematic qualitative analysis.

29.08.18 Diazepam*, lorazepam, Merprobamate

31.08.18 Hypnoties:- Phenobarbitone*, Butobatbitone, Cyelobarbitone

3.9 Hypnoties 3 4.09.18 Nitrazepam, Glutethimide*, Methyptylone To identify the given organic drug (sample D -8) by

5.09.18 Paraldehyde, Triclofos Sodium systematic qualitative analysis

General

7.09.18 General Anaestheties- Halothane* Cyclopropane*,

3.10 3 10.09.18 Diethyl ether*, Methohexital sodium

Anaestheties

11.09.18 Thiopental sodium, Trichloroethylene To identify the given organic drug (sample D -9) by

Antidepressant

12.09.18 Antidepressant Drugs- Amitriptyline, Nortiyptyline systematic qualitative analysis.

3.11 3 14.09.18 Imipramine*, Phenelzine

Drugs

17.09.18 Tranyleypromine To identify the given organic drug (sample D -10) by

18.09.18 Analeptics- Theophyline, systematic qualitative analysis.

3.12 Analeptics 3 19.09.18 Caffeine*, Cora mine* To perform and report identification test on given sample

21.09.18 Dextroamphetamine.

of Aspirin or Acetyl salicylic acid as per I.P.

24.09.18 Adrenergic Drugs- Adrenaline*, Nor adrenaline,

3.12 Adrenergic Drugs 3 25.09.18 Isoprenaline*, Phenylephrine, Salbutamol,

26.09.18 Terbutaline, Ephedrine*, Pseudo ephedrine To perform and report identification test on given sample

3.13 Adrenergic

3

28.9.18

Adrenergic Antagonist- Tolazoline, of Paracetamol as per I.P

01.10.18

Antagonist Propranolol, Practolol

03.10.18

05.10.18 Cholinergic Drugs- Neostigimine* To perform and report identification test on given sample

3.14 Cholinergic Drugs 3 08.10.18 Pyridostigmine, pralidoxime

of Ascorbic acid as per I.P

09.10.18 Pilocarpine, Physostigmine

Lesson Plan for PHARMACEUTICAL CHEMISTRY-II (2132) (Session 2018-19) |

12.10.18 Cholinergic Antagonists- Atropine, Hyoscine

Cholinergic

3.15 3 15.10.18 Homatropine, Propantheline, Benztropine

Antagonists

16.10.18 Tropic amide, Biperden To perform and report identification test on given sample of Sulphamethoxazole as per I.P.

17.10.18 Diuretic Drugs- Furosemide*, Chlorothiazide,

3.16 Diuretic Drugs 3

19.10.18 Hydrochlorothiazide*, Benzthiazide, Urea*

22.10.18 Mannitol, Ethacrynic Acid

To perform and report identification test on given sample

23.10.18 Cardiovascular Drugs- Ethyl nitrite, Glyeeryl trinitrate

of Ampicillin as per I.P.

3.17 Cardiovascular

3

26.10.18 Alpha methl dopa, Guancthidine

Drugs

29.10.18 Clofibrate, Quinidine

Hypoglycemic

30.10.18 Hypoglycemic Agents- Insulin, Chlorpropamide* To perform and report identification test on given sample

3.18 3 31.10.18 Tolbutamide, Glibeneclamide of Promethazine hydrochloride as per I.P.

Agents

2.11.18 Phenformin*, Metformin

Coagulants and

5.11.18 Coagulants and Anti Coagulants- Heparin

3.19 3 6.11.18 Thrombin, Menadione To perform and report identification test on given sample

Anti Coagulants

12.11.18 Bishydroxycoumarin, Warfarin Sodium of Prochlorperazine maleate as per I.P.

13.11.18 Local Anesthetics- Lignocaine

3.20 Local Anesthetics 3 14.11.18 Procaine

16.11.18 Benzocaine

19.11.18 Histamine, Diphen hydramine, To perform and report identification test on given sample

Histamine and

of Quinine sulphate as per I.P.

3.21 Anti Histaminic 3 20.11.18 Promethazine, Cyproheptadine, Mepyramine,

Agents

21.11.18 Pheniramine, Chlorpheniramine.

26.11.18 Analgesics and Anti- Pyretics- Morphine, Pethidine

Analgesics and

To synthesize Acetanilide from Aniline and to find out its

27.11.18 Codeine, Methadone, Aspirin, Paracetamol

3.22 3 percentage practical yield and melting point.

Anti- Pyretics

28.11.18 Analgin, Dextropropoxyphene, Pentazocine

Lesson Plan for PHARMACEUTICAL CHEMISTRY-II (2132) (Session 2018-19) |

Non- Steroidal

30.11.18 Non- Steroidal anti- inflammatory Agents- Indomethacin

3.23 anti-

3

3.12.18 Phenybutazone, Oxyphen butazono

inflammatory To synthesize Benzoic acid from Benzamide and to find

Agents- out its percentage practical yield and melting point.

4.12.18 Ibuprofen

5.12.18 Thyroxin and Antithyriods- Thyroxin

3.24 Thyroxin and

3

7.12.18

Methimazole, Methylthiourcil

Antithyriods

10.12.18 Propylthiouracil To synthesize Phenyl Benzoate from Phenol and to find

out its percentage practical yield and melting point. 11.12.18 Diagnostic Agents- Iopanioc Acid, Propyliodone

Sulfobromophty Sodium, Indigotindisulfonate

3.25 Diagnostic Agents 4 12.12.18 Sodium ( Indigo Carmine), Evans Blue To synthesize picric acid from Phenol and to find out its percentage practical yield and melting point 14.12.18 Congo Red, Fluorescin Sodium

Anticonvulsants 17.12.18 Anticonvulsants

Cardiac, 18.12.18 Cardiac, glycosides

3.26 glycosides

5 19.12.18 Antiarrhythmic

Antiarrhythmic 21.12.18 Antihypertensive To visit chemical/analytical laboratory and write a report

Antihypertensive

of it. Vitamins

Vitamins 24.12.18

26.12.18 Steroidal Drugs- Betametazone, Cortisone

3.27 Steroidal Drugs 4 28.12.18 Hydrocortisone, prednisolone 31.12.18

Progesterone, oestradiol

Nandrolone

Anti- Neoplastic Drugs- Actinomycins, Azathioprine

Anti- Neoplastic

Busulphan, Chlorambucil Cisplatin

3.28 5 cyclophosphamide, Daunorubicin, Hydrochloride

Drugs

Fluorouracil, Mercaptopurine

Methothrexate, Mytomycin

References:

1. Pharmaceutical Chemistry – II , Md. Ali 2. Pharmaceutical Chemistry-II, Ashutosh kar 3. A Textbook of Medicinal Chemistry, Harkishan Singh & V.K. Kapoor

Lesson Plan for PHARMACEUTICAL CHEMISTRY-II (2132) (Session 2018-19) | 35

DIPLOMA IN PHARMACY (SECOND YEAR)

SUBJECT : PHARMACOLOGY & TOXICOLOGY (2133)

SUBJECT TEACHER : VISITING FACULTY-I

TOTAL HOURS ASSIGNED : Theory: 75 Hours (3 Hours/week), Practical: 50 Hours (Total 4 Hours/Week, 2 Hours/Week per Batch)

Unit/ Title of Unit/Chapter Hours Date Theory Topic Practical Practical Topic Chapter Allotted Day day

Introduction to 2.07.18, 2.07.18

Introduction to Pharmacology, scope of Introduction to pharmacology & 1 Pharmacology, scope of 1 1 Pharmacology- introduction, pharmacokinetics & toxicology laboratory.

Pharmacology pharmacodynamics & scope of pharmacology.

5.07.18, 6.07.18

Routes of administration of drugs, their 1,2

Routes of administration of

2 advantages and disadvantages-Enteral route, Parenteral route

2 drugs, their advantages and 2

9.07.18, 9.07.18

Routes of administration of drugs, their

disadvantages.

3 advantages and disadvantages-Topical & other

routes

Absorption,

12.07.18,

13.07.18 4 Various processes of absorption of drugs and the 3,4 Introduction to Computers.

factors affecting them

3 Distribution,Metabolism &

3

16.07.18,

16.07.18 5 Metabolism, Distribution

Excretion

19.07.18 6 Excretion of drugs

General mechanism of drugs 20.07.18,

23.07.18 7 Drug receptor interaction- Ligand Gated Ion To select the animals for experimental

4 action and the factors which

2 channel, G-Protien coupled receptor use in pharmacology.

modify drug action 23.07.18 8 Enzyme linked receptor & Intracellular receptor 5,6

26.07.18

27.07.18,

30.07.18

9 General Anaestheies, adjunction to anesthesia,

intravenous Ana esthetics

30.07.18, 2.08.18

10 Analgestic antipyretics and non-steroidal, anti- 7,8 To study the common instrument &

Inflammatory drugs equipment and equipments used in

experimental pharmacology. Drugs acting on the Central

3.08.18 11 Narcotic analgesics

5 (I,II) 8 6.08.18, 6.08.18 12 Anti-rheumatic and antigout remedies 9,10 To study the various laboratory Nervous System

techniques used in experimental

9.08.18 13 Sedatives and Hypnotics

pharmacology. 10.08.18 14 Psychopharmacological agents

13.08.18,

13.08.18 15

Anti convulsants, analeptics, Centrally acting 11,12 To prepare physiological salt

muscle relaxants

solutions

16.08.18 16 Anti- Parkinsonism agents, Local Anesthetics

17.08.18 17 Cholinergic drug 13,14 To study the effect of adrenaline on

20.08.18

heart rate & force of contraction on 18

Cholinergic drug isolated frog heart by using software.

20.08.18 19 Anti- Cholinergic drugs 15,16 To study the effect of calcium ions &

23.08.18

potassium ions on heart rate & force 20 Adrenergic drugs

of contraction on isolated frog heart

Drug acting on autonomic 27.08.18

27.08.18 21 Anti- cholinesterase drugs

5 (III) 10

by using software.

nervous system

30.08.18 22 Adrenergic receptor blockers 17,18 To study the effect of acetylcholine on

31.08.18

heart rate & force of contraction on 23 Neurone blockers

isolated frog heart by using software. 24 Ganglion blockers

25 Neuromuscular blockers 19,20 To study the effect of acetylcholine on

26 Drugs used in myasthenia gravis isolated rectus abdominus muscle by

using software.

5 (IV) Drugs acting on eye 2 6.09.18 27 Drugs acting on eye, mydriatics 21,22 To study the effect of acetylcholine on 7.09.18 28 Drugs used in glaucoma ileum of guinea pig by using software.

10.09.18

10.09.18 29 Drugs acting on respiratory system-Respiratory

Drugs acting on respiratory

stimuntants

3

system 13.09.18 30 Bronchodilators, Nasal decongestants 23,24 To study the effect of mydriatics on

14.09.18 31 Expectorants and Antitussive agents rabbit cornea by using software.

17.09.18 32 Antacids

5 (VI) Drugs acting on

4 17.09.18 33 Physiological role of histamine and serotonin 25,26 To study the effect of acetylcholine on

gastrointestinal tract 20.09.18 34 Histamine and Antihistamines

ileum of guinea pig by using software.

21.09.18 35 Prostaglandins 27,28 To study the effect of mydriatics on 24.09.18 36 Cardio Vascular drugs rabbit cornea by using software. 24.09.18 37 Cardio tonics

Drugs acting on Cardio 27.09.18 38 Anti-arrhythmic agents To study the effect of miotics on

5 (VII) 7 28.9.18

39 Antianginal agents 29,30 rabbit cornea by using software. Vascular system 1.10.18, 1.10.18 40 Antihypertensive agents

4.10.18, 5.10.18 41 Peripheral vasodilators To study the effect of digitalis on

31,32 heart rate & force of contraction on 8.10.18, 8.10.18 42 Drugs used in atherosclerosis

isolated frog heart by using software. 11.10.18 43 Haematinics

Drugs acting on the blood

12.10.18 44 Coagulants 33,34 To observe the effect of convulsant & 5 (VIII) 6 15.10.18 45 Anti-coagulants anticonvulsant in mice by using CD.

and blood forming organs

15.10.18 46 Haemostatic

19.10.18 47 Blood substitutes 35,36 To study the effect of chlorpromazine

22.10.18 48 Blood expanders on animal behaviour in mice by using 22.10.18,

25.10.18 49 Physiology of renal tract- excretion, urine the CD.

5 (IX) Drugs affecting renal

3 formation & UTI

function 26.10.18 50 Diuretics Visit to hospital for observing the

29.10.18

51 Antidiuretics 37,38

reaction 29.10.18,

2.11.18 52 Hormones –Introduction to Pituitary gland

hormones, Thyroid & Adrenal gland hormones

5 (X) Androgens & related

5

5.11.18

5.11.18 53 Hormone antagonists-hypoglycemic agents 39,40 Visit to hospital for observing the substance 8.11.18 54 Antithyroid drugs

reaction of dug in the patient.

12.11.18,

12.11.18 55 Sex hormones and oral contraceptive

15.11.18 56 Corticosteroids 41,42 To understand the adverse drug 16.11.18 57 Car-minatives, Digestants & Bitters reaction and monitor the same

Drugs acting on digestive

19.11.18

19.11.18 58 Antacids and drugs used in Peptic Ulcer

5 (XI) 5 22.11.18

59 Purgative and Laxatives

To understand the adverse drug system

26.11.18 60 Ant-diarrhoeals & Emetics 43,44 reaction and monitor the same

26.11.18,

29.11.18 61 Anti-emetics, Anti-spasmodic

30.11.18 62 Urinary Anti-septic 45,46 To understand the adverse drug

3.12.18,3.12.18 63 Sulphonamides reaction and monitor the same

Chemotherapy of microbial

6.12.18, 7.12.18 64 Penicillin, Streptomycin 47,48 To visit a nearby hospital

5 (XII) 7 10.12.18,

10.12.18 65 Tetracylines and other antibiotics

disease

13.12.18 66 Antiubercular agents

14.12.18 67 Antifungal agents, antiviral drugs 49,50 To visit a nearby hospital

17.12.18, 17.12.18 68 Antiubercular drugs

20.12.18,

21.1218 69

Malaria- Introduction, Life cycle of Malaria

Chemotherapy of protozoal parasite

5 (XII) 3

disease 24.12.18,24.12.18 70 Antimalarials 51,52 To visit a nearby hospital

27.12.18 71 Anthelmintic drugs

28.12.18,31.12.18

72 Cancer- introduction & cause of cancer, types of

5 (XIII) Chemotherapy of cancer. 2 cancer

31.12.18 73 Anticancer drugs To visit a nearby hospital

5 (XIX) Disinfectants and Anti-

2 74 Disinfectants 53,54

septic

75 Anti-septic

References:

1. Essentials of Medical Pharmacology, K.D. Tripathi 2. Textbook of Pharmacology, F.S.K. Barar 3. Lippincott’s Handbook of Pharmacology 4. Pharmacology & Pharmacotherapeutics, Santoshkar & Bhandarkar

DIPLOMA IN PHARMACY (SECOND YEAR)

SUBJECT : PHARMACEUTICAL JURISPRUDENCE (2134)

SUBJECT TEACHER : Visiting Faculty-II

TOTAL HOURS ASSIGNED : 50 Hours (2 Hours/week)

Unit/ Title of Unit/Chapter Hours DATE Theory Topic Chapter Allotted day

4.07.18 1 Advent of allopathic system 5.07.18 2 The 19th & early 20th century

1 Pharmaceutical Legislation in India 5 11.07.18 3 Drug enquire committee 12.07.18 4 The drug act 18.07.18 5 Pharmacy act & other legislation 19.07.18 6 Principles and significance of Professional Ethics.

7 Principles and significance of Professional Ethics. 25.07.18

26.07.18 8 significance of Professional Ethics 2 Principles and significance of Professional Ethics 5 1.08.18

9 Critical study of the code of Pharmaceutical Ethics drafted by Pharmacy

Council in India

2.08.18

10 Critical study of the code of Pharmaceutical Ethics drafted by Pharmacy

Council in India

8.08.18 11 Introduction 9.08.18 12 Objective of the act 16.08.18 13 The pharmacy council of india

3 Pharmacy Act 1948 7 23.08.18 14 Function of pharmacy council of india 29.08.18 15 State pharmacy council & joint state pharmacy council 30.08.18 16 Function of State pharmacy council 5.09.18 17 Commission of enquiry & rules by state government 6.09.18 18 Introduction of The Drugs and Cosmetics Act 1940 12.09.18 19 Import of drugs schedule (C & C1) & schedule X 13.09.18 20 Manufacture of drugs schedule (C & C1)

4

The Drugs and Cosmetics Act 1940

7 19.09.18 21 Manufacture of drugs schedule X

20.09.18 22 Sales of drugs retail

26.09.18 23 Sales of drugs wholesale 27.09.18 24 Labeling & packing of drugs

Lesson Plan for PHARMACEUTICAL JRUISPRUDENCE (2133) (Session 20118-19) |

3.10.18 25 Introduction 4.10.18 26 Definition as per act

The Drugs and magic Remedies (Objectionable 11.10.18 27 Prohibited advertisement

5 7 17.10.18

28 Prohibition on import & export of advertisement Advertisement) Act, 1954 25.10.18 29 Prohibition on import & export of advertisement

31.10.18 30 Penalties as per act 8.11.18 31 Miscellaneous- jurisdiction to try offences, saving of other laws etc. 14.11.18 32 Introduction of act

Narcotic Drugs and Psychotropic Substances Act, 21.11.18 33 Narcotic drugs

6 5 22.11.18

34 Psychotropic substance 1985 28.11.18 35 Controlled operation

29.11.18 36 Administrative agencies 5.12.18 37 Introduction of act

7(I) Latest Drugs (price control) Order-1985 3 6.12.18 38 Price of bulk drugs 12.12.18 39 Retail price of formulation, Miscellaneous 13.12.18 40 Introduction of act, import of poison

7(II) Poison Act ,1919 3 19.12.18 41 Possession & sales of poison 20.12.18 42 Penalties for offence & issue of warrants 26.12.18 43 Introduction of act, manufacture in bond

7(III) Medical and Toilet Preparation (Act, 1955) 4 26.12.18 44 Manufacture outside bond 45 Manufacture of Ayurveda, homeopathic & patent

46 Warehousing & export of alcoholic preparation 47 Introduction of act

7(IV) Medical Termination of Pregnancy Act, 1971 4 48 Termination of pregnancy

49 Offence & penalties

50 Rules & regulation

References: 1. Website: www.pci.nic.in 2. Pharmaceutical Jurisprudence by N.K. Jain 3. Pharmaceutical Jurisprudence by R.M. Mehta

Lesson Plan for PHARMACEUTICAL JRUISPRUDENCE (2133) (Session 20118-19) |

DIPLOMA IN PHARMACY (SECOND YEAR)

SUBJECT : DRUG STORE & BUSSINESS MANAGEMENT (2135)

SUBJECT TEACHER : VISITING FACULTY II

TOTAL HOURS ASSIGNED : 75 Hours (3 Hours/week)

Unit/ Title of Unit/Chapter Hours DATE Theory Day Topic Chapter Allotted

2.07.18, 3.07.18,

4.07.18 1 Trade- Type of Trade, Domestic trade, 6.07.18, 9.07.18 2 International trade 10.07.18, 11.07.18 3 Industry – Introduction & Type of industries

1 Introduction 7 13.07.18, 16.07.18 4 Commerce Functions and Subdivision of Commerce, 17.07.18, 18.07.18 5 Introduction to elements of economics

20.07.18, 23.07.18,

24.07.18 6 Management of financial resources 25.07.18, 27.07.18 7 Management of financial resources 1.08.18, 3.08.18 8 Introduction of pharmaceutical bussiness 6.08.18, 7.08.18 9 Type of business-retail & whole sale

2 Forms of Business Organization

6 8.08.18, 10.08.18 10 Partnership & type of partnership

13.08.18, 14.08.18 11 Retail & whole sale

17.08.18, 20.08.18 12 Type of retailers & wholesalers 21.08.18, 24.08.18 13 Type of retailers & wholesalers 27.08.18, 28.08.18 14 Introduction to drug distribution 29.08.18, 31.08.18 15 Drug distribution

3

Channels of Distribution

6 5.09.18, 7.09.18 16 Channel of drug distribution

10.09.18, 12.09.18 17 Wholesale

14.09.18, 17.09.18 18 Retailing of drugs 18.09.18, 19.09.18 19 Procedure adopted for drug distribution 21.09.18, 24.09.18 20 Drug House Management- Selection of site, and 25.09.18, 26.09.18 21 Drug store-Space requirement & Layout 28.09.18, 31.09.18 22 Legal requirements for opening a medical store 1.10.18, 3.10.18 23 Importance and objectives of purchasing

4 Drug House Management 8 5.10.18, 8.10.18 24 Selection of suppliers 9.10.18, 25 Credit information, tenders 12.10.18-15.10.18 26 Contracts and price determination and

16.10.18-17.10.18

27 Legal requirements thereto

Lesson Plan for DSBM (2135) (Session 2018-19) |

Inventory Control 8

19.10.18-22.10.18 28 Objects and importance 23.10.18-26.10.18 29 Drug store function & storage techniques of materials (drugs)

29.10.18-30.10.18

30 Procedure for purchasing- determination of stock, placing order, selection of supplier etc.

5 31.10.18-2.11.18 31 Modern Techniques like ABC, VED Analysis 5.11.18-6.11.18 32 The Lead-Time, Buffer Stock 12.11.18-13.11.18 33 Inventory carrying cost, 14.11.18-16.11.18 34 Safety stock, minimum and maximum stock levels, 19.11.18,20.11.18 35 Economic order quantity scrap and surplus disposal 26.11.18-27.11.18 36 Sales Promotion- introduction & importance 28.11.18-30.11.18 37 Sales promotion techniques- Direct & Indirect incentives, other techniques 3.12.18-4.12.18 38 Market Research

6 Sales Promotion 8 5.12.18-7.12.18 39 Salesmanship- Definition, recruitment of salesman,

10.12.18-11.12.18 40 Qualities of a salesman,

12.12.18-14.12.18 41 Advertising- importance, different source of Advertising like radio, television 17.12.18-18.12.18 42 Pamphlets, Medicine catalogue, CIMS & MIMS 21.12.18-24.12.18 43 Window Display

7 Recruitment, training, evaluation

7

26.12.18-28.12.18 44 Pharmacist, general requirement and compensation of the 28.12.18 45 Recruitment- recruitment procedure, educational qualification & other requirements pharmacist 46 Recruitment- recruitment procedure, educational qualification & other requirements 47 characteristics of Ideal pharmacist 48 Training for pharmacist 49 Evaluation of pharmacist 50 Compensation of the pharmacist

51 Introduction to the accounting concepts 52 Conventions

8 (a) Banking & finance services 5 53 Double entry Book keeping 54 Different types of accounts.

55 Different types of accounts.

56 Cash book 57 Cash book

8 (b) Banking & Finance services 5 58 Cash book

59 Cash book

60 Cash book

Lesson Plan for DSBM (2135) (Session 2018-19) |

61 General Ledger 62 General Ledger

8 (c) Banking & Finance services 5 63 Trial Balance 64 Trial Balance 65 Trial Balance 66 Profit Account 67 Profit Account

8 (d) Banking & Finance services 5 68 Loss Account 69 Balance Sheet 70 Balance Sheet 71 Simple technique of analyzing financial statements 72 Simple technique of analyzing financial statements

8 (e) Banking & Finance services 5 73 Simple technique of analyzing financial statements 74 Simple technique of analyzing financial statements 75 Simple technique of analyzing financial statements

References:

1. Drug Store & Business Management, R.M. Mehta 2. Drug Store & Business Management, S.K. Aggrawal & Rajesh Khanna

Lesson Plan for DSBM (2135) (Session 2018-19) |

DIPLOMA IN PHARMACY (SECOND YEAR)

SUBJECT : HOSPITAL AND CLINICAL PHARMACY (2136)

SUBJECT TEACHER : VISITING FACULTY-I

TOTAL HOURS ASSIGNED : Theory: 75 Hours (3 Hours/week), Practical: 75 Hours (Total 6 Hours/Week, 3 Hours/Week per Batch)

Unit/ Title of Hours DATE Theory Topic Practical Practical Topic Chapter Unit/Chapter Allotted day Day

3.07.18 1 Hospitals- Definitions, Function To know your hospital & clinical

1 Hospitals 4 4.07.18 2 Hospitals-Classification based or various criteria 1,2 laboratory. 5.07.18 3 Organization of Hospitals, Management

10.07.18 4 Health delivery system in India 3,4

To prepare & evaluate water for injection 11.07.18 5 Hospital Pharmacy – Definition, Functions and

12.07.18 6 Objectives of Hospital Pharmaceutical Services. To perform the test for pyrogen.

2 Hospital

5

17.07.18 7 Location, Layout, flow chart of material and men. 5,6

18.07.18

Personnel and facilities requirements including

Pharmacy

8

equipment’s based on individual and basic needs

19.07.18 9

Requirements and abilities required for Hospital To perform the hydrolytic resistance test

Pharmacists on glass bottles used for transfusion fluids

4

24.07.18 10 Out- patient services, In-patient services. 7,8

Drug Distribution

25.07.18 11 Types of services (ii) Detailed discussion of Unit Dose

system, Floor Ward Stock system

3 system in

26.07.18 12 Satellite Pharmacy Services, Central Sterile Services

To evaluate the plastic transfusion bottles Hospitals

1.08.18 13 Bed Side Pharmacy 9,10 used for large volume parenteral.

2.08.18 14 Economic considerations, estimation of demand To prepare & submit 100ml of 5% w/v

Dextrose Intravenous infusion. 7.08.18

8.08.18 15 Sterile manufacture- Large and small volume parented

facilities, requirements 11,12

Manufacturing

4 5 9.08.18

14.08.18 16 Sterile manufacture- Layout, production planning, and

man- power requirements

16.08.18

21.08.18 17 Non-sterile manufacture- Liquid orals, externals, Bulk To prepare & submit 100ml of 0.9% w/v

concentrate 13,14

Sodium Chloride Intravenous infusion.

23.08.18 18 Procurement of stores and testing of raw material

5 Nomenclature and

4 28.08.18 19 Towel clips, Scalpels & their blades

uses of surgical

29.08.18 20 Forceps, scissors 15,16 To prepare & submit 100ml of Compound

Lesson Plan for HCP (2136) (Session 2018-19) |

instruments 30.08.18 21 Needles, Rubber Catheters Sodium Chloride injection as per I.P.

4.09.18 22 Health accessories

P.T.C/ Hospital

4.09.18 23 P.T.C (Pharmacy Therapeutic Committee) To prepare & submit 100ml of Compound 6 2

5.09.18 6.09.18

24 Hospital formulary system and their organization, Sodium lactate injection as per I.P. formulary 17,18

functioning, composition (Hartmann’s Solution).

11.09.18 25 Information center, source of information

Drug information 12.09.18 26 Guidelines for setting up a DIC To prepare & submit 100ml of Compound

service and Drug

19,20 Sodium Chloride & dextrose injection as 7 4

13.09.18 18.09.18

27 Drug information Centre Location & Function Information per I.P.

Bulletin 19.09.18 20.09.18

28 Drug Information Bulletin & role of computers in To prepare & submit 100ml of 1.6 % w/v pharmacy

21,22 Sodium Chloride hypertonic injection as

25.09.18 29 Surgical dressing like cotton, gauze per I.P.

26.09.18 30 Surgical dressing- Bandages adhesive tapes

8 Surgical dressing 4

27.09.18 3.10.18

31 Surgical dressing - Pharmacopoeia tests for quality To prepare & submit 100ml of 1.4 % w/v 23,24 Sodium bicarbonate intravenous infusion

B.P. 4.10.18

9.10.18 32 Other hospital supply e.g. I. V sets, Ryals tubes, Catheters, To evaluate Absorbent cotton wool I.P. syringes etc

25,26

11.10.18 33 Application of computer in maintenance of records

Drug store 16.10.18 34 Inventory control techniques

9 management & 4 17.10.18 23.10.18

35 Medication monitoring, drug information and data storage To determine the sinking time & water

inventory control

27,28 holding capacity for Absorbent cotton per 25.10.18

30.10.18 36 Retrieval in hospital and retail pharmacy establishments

I.P. 31.10.18

6.11.18

37 Introduction to Clinical Pharmacy Practice- Definition & To determine LOD of Absorbent cotton per

10 Clinical Pharmacy 2 scope. I.P

8.11.18

13.11.18 38 Introduction to Clinical Pharmacy Practice- Definition & 29,30

scope.

Modern

14.11.18 39 Pharmacists and patient counseling

11 3 15.11.18 40 Advice for the use of common drugs To study different types of sterilizers dispensing aspects 31,32 20.11.18 41 Medication history (Autoclave & Hot air oven).

21.11.18

22.11.18

42 Common daily terminology used in the practice of To sterilize surgical instrument

12 Common daily

2 medicine

terminology 27.11.18

28.11.18 43 Common daily terminology used in the practice of 33,34

medicine

13 Disease,

7 29.11.18 44 Tuberculosis

manifestations 4.12.18 45 Hepatitis 35,36 To sterilize syringe, needles & glass wares

Lesson Plan for HCP (2136) (Session 2018-19) |

and path 5.12.18 46 Rheumatoid Arthritis

physiology 6.12.18 47 Cardio-vascular diseases

11.12.18 48 Epilepsy, Diabetes To sterilize rubber gloves & rubber tubing

13.12.18 49 Peptic ulcer 37,38

18.12.18 50 Hypertension

Physiological

19.12.18 51 Hematological parameters To sterilize hospital fabrics

14 3 20.12.18 52 Urine examination

parameters 39,40

23.12.18 53 Stool examination

27.12.18 54 Definition and Introduction.

55 Mechanism of drug interaction. To sterilize surgical dressing

Drug Interactions 56 Drug- Drug interaction with reference to analgesics,

15 5 diuretics

41,42

57 Drug- Drug interaction with reference to cardio vascular

drugs, gastro-intestinal agents vitamins and hypoglycemic

agents.

58 Drug- food interaction.

Adverse Drug

59 Definition & Significance To study the use of computers inj

hospitals for registration of patient in

60 Drug- Induces diseases

16 Reaction 4 43,44

opd/ipd, case history & prospective check 61 Drug- Induces diseases

list. 62 Teratogenecity

63 Introduction, general treatment of poisoning, To study a typical hospital organization&

17 Drug in Clinical

4 64 Systematic Antidots, treatment of insecticide poisoning

45,46 prepare a project report

Toxicity 65 Treatment of heavy metal poison, Narcotic drugs,

66 Treatment of Barbiturate, organ phosphorus poisons

67 Drug dependences, Drug abuse, To study the role of Pharmacist in First

18 Abused Drugs 3 68 Addictive drugs 47,48 Aid 69 Treatments & complications

70 Bioavailability & factor affecting the Bioavailability To determine weight per unit area of

19 Bio-availability 4 71 Purpose of bioavailability studies

49,50 Absorbent cotton ribbon gauze I.P.

72 Bioavailability determination

73 Needs for bioavailability studies

Lesson Plan for HCP (2136) (Session 2018-19) |