dietary fibre : appetite control and weight …...satiety hormones: effect of molecular weight beck...

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Confidential Confidential © Tate & Lyle 2018 Dietary Fibre : Appetite Control and Weight Management Dr Kavita Karnik, VP, Global Nutrition and OI

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Page 1: Dietary Fibre : Appetite Control and Weight …...Satiety hormones: effect of molecular weight Beck et al. 2009 * Change in peptide Y-Y responses to different treatments ‘oat beta-Glucan

Confidential

Confidential© Tate & Lyle 2018

Dietary Fibre : Appetite Control and Weight ManagementDr Kavita Karnik, VP, Global Nutrition and OI

Page 2: Dietary Fibre : Appetite Control and Weight …...Satiety hormones: effect of molecular weight Beck et al. 2009 * Change in peptide Y-Y responses to different treatments ‘oat beta-Glucan

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The risk transition

Global health risks: mortality and burden of disease attributable to selected major risks. WHO 2009

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Obesity in numbers

3

McKinsey Global Institute, Nov 2014

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Confidential© Tate & Lyle 2018, Confidential

Role of fibresObesity represents long-term result of an imbalance between energy intake and energy expenditure ---- the most obvious link between dietary fibre and obesity development is through its effects on energy intake control mechanisms

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What are fibres?

Carbohydrate polymers with a Degree of Polymerisation (DP) of 3 or more

Resistant to absorption and human enzymes in the small intestine

Have a beneficial physiological effects

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“Fibre” means carbohydrate polymers with three or more monomeric units, which are neither digested nor absorbed in the human small intestine

Fibre ingredients should also have a beneficial physiological effect(2) demonstrated by generally accepted scientific evidence

(1) Directive 2008/100/EC, Annex II published 29th October 2008;; (2) such as: decrease intestinal transit time, increase stool bulk, is fermentable by colonic microflora, reduce blood total cholesterol, reduce blood LDL cholesterol levels, reduce post-prandial blood glucose, or reduce blood insulin levels,....; Also repeated in Commission Guidance methods of analysis December 2012

EU Fibre definition (Directive 2008/100/EC, Regulation (EU) 1169/2011)(1)

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ConfidentialMela et al, 2017 6

Structural/functional properties of DF and effects on eating behaviour

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Satiety Index : selected foods

Page 8: Dietary Fibre : Appetite Control and Weight …...Satiety hormones: effect of molecular weight Beck et al. 2009 * Change in peptide Y-Y responses to different treatments ‘oat beta-Glucan

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Global fibre intakes and recommendations

© Tate & Lyle 2018

Auestad N, et al. Contribution of Food Groups to Energy and Nutrient Intakes in Five Developed Countries. Nutrients. 2015 Jun 8;7(6):4593-618.Murphy N, et al. Dietary fibre intake and risks of cancers of the colon and rectum in the European prospective investigation into cancer and nutrition (EPIC). PLoS One. 2012;7:e39361.Wang HJ et al. Trends in dietary fibre intake in Chinese aged 45 years and above, 1991-2011. Eur J Clin Nutr. 2014 May;68(5):619-22.CODEX-aligned dietary fibre definitions help to bridge the ‘fibre gap’. Jones JM. Nutr J. 2014;13:34.Flores M, Macias N, Rivera M, et al. Dietary patterns in Mexican adults are associated with risk of being overweight or obese J Nutr. 2010 Oct;140(10).Dehghan M, et al. Relative validity of an FFQ to estimate daily food and nutrient intakes for Chilean adults. Public HealthNutr. 2013 Oct;16(10):1782-8.Sardinha AN, Canella DS, Martins AP, et al. Dietary sources of fibre intake in Brazil. Appetite. 2014 Aug;79:134-8.

Page 9: Dietary Fibre : Appetite Control and Weight …...Satiety hormones: effect of molecular weight Beck et al. 2009 * Change in peptide Y-Y responses to different treatments ‘oat beta-Glucan

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ConfidentialIbarra et al, 2015. 9

Decreased energy intake after consumption of polydextrose

Systematic review and meta-analysis to examine the effects of polydextrose on energy intake at an ad libitum lunch

6 studies were identified with data for a total of 120 subjects

Energy intake at a subsequent ad libitum lunch indicates a significant effect of polydextrose in a dose-dependent manner over the placebo (p < 0.01)

Energy intake for the rest of the day or dinner and the total daily energy intake were not statistically significant

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Effect of polydextrose on energy intake

Energy intake at the ad libitum lunchtime test meal following fixed energy liquid preloads containing different amounts of polydextrose. n 21; twelve men and nine women

Astbury at al, 2013

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PromOat® beta glucan and satiety

a

a

a

a

b bb

b b bb

a,bb

b

b b

Hartvigsen et al. 2014.

PromOat® beta glucan and satiety

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Satiety hormones: effect of molecular weight

Beck et al. 2009

*

Change in peptide Y-Y responses to different treatments

‘oat beta-Glucan improves satiety and release of

cholecystokinin is likely to be part of the mechanism’

Satiety hormones: effect of molecular weight

Page 13: Dietary Fibre : Appetite Control and Weight …...Satiety hormones: effect of molecular weight Beck et al. 2009 * Change in peptide Y-Y responses to different treatments ‘oat beta-Glucan

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Soluble Corn Fibre reduces glucose and insulin response

Significant difference between treatments at each time point at p<0.05.

Data expressed as mean ± SEM.

© Tate & Lyle 2018

Kendall et al. JACN. 2008;27:711-718.

Soluble Corn Fibre Soluble Corn Fibre

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Additional health benefits of soluble corn fibre

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Growing awareness leads to growing demand for fibre :not only for digestive health but for weight management

Source: 1) Tate & Lyle Proprietary Research, Fibre AAU 2016, 11 countries, 8800 consumers

Consumers Desire for More Fibre in their Diet1

60%USA

44%EUR

70%LATAM

48%APAC

50%MiddleEast

52%Global

Reasons for Fibre Consumption1

Healthy metabolism

Digestive health

Healthy diet

Regularity

Full for longer

Weight management

Tastes great

Fit body

Lowers cholesterol

Heart health

56%

49%

45%

40%

37%

33%

32%

30%

27%

25%

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Consumers want fibre across many categories

Source: 1)Tate & Lyle Proprietary Research, Global Consumer Ingredient Perception Research, November 2017, 9 countries, 3002

consumers

Purchase Intent - Top 10 Categories Impacted by Inclusion of Fibre1

% Very/likely to buy

55%Cereal

49%Yogurt

45%Cookies

45%Soup

45%Crackers

45%Juice

Drinks

44%Cakes

44%Bars

40%Ice Cream

39%Salty

Snacks

Copyright © Tate & Lyle PLC 2018

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Consumers are clear that TASTE is critical

172017 International Food Information Council (IFIC) Food & Health Survey

84% of consumers agree that

taste is the most important factor when choosing what

to eat and drink

© Tate & Lyle 2018

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North America

+15%

Europe

+16%Asia

Pacific

+18%Middle East Africa

+10%

Latin America

+33%

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Food and beverage companies responding to help consumers live healthier lives

Global growth of product

launches with ingredient fibre1

5YCAGR 2013-2017

+23%Beverages

+26%Bakery

+32%Soups, Sauces, and

Dressings

+14%Dairy

Global growth of product launches with ingredient fibre1

5YCAGR 2013-2017

Source: Mintel GNPD 2013-2017 - Ingredients matches "soluble corn fibre" or "polydextrose" or "soluble oat fibre"Copyright © Tate & Lyle PLC 2018

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Thousand IslandDressing,

Reference / 100 g

Thousand IslandDressing,

No added sugar / 100g

Energy 876 kJ / 209 kcal 537 kJ / 128 kcal

Fat 16.0 g 10.6 g

of whichsaturates

1.1 g 0.2 g

Carbohydrate 15.0 g 5.6 g

of which sugars 10.0 g 1.6 g

Fibre 0.2 g 3.8 g

Protein 1.2 g 0.7 g

Salt 1.9 g 1.4 g

Thousand Island dressing – no added sugar, reduced fat and fibre enriched

Featuring PROMITOR® Soluble Fibre, OPTIMIZER Stevia™ 4.10, SPLENDA® Sucralose and HAMULSION® Stabiliser System

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ConfidentialJones JM. CODEX-aligned dietary fibre definitions help to bridge the 'fibre gap'. Nutr J. 2014

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Fibres provide various opportunities to help weight management

A varied diet that uses fibre-fortified foods together with fibre-rich foods has multiple benefits in addition to weight management

Soluble fibres provide an easy-to-use tool to make our foods healthier while preserving the taste

Health benefits from the

different dietary fibre types and

functions

Closes the fibre gap while

staying within a day’s calorie

allotment

Summary