developed methods

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Separation of antivirals using organic solvents blending technique Ledipasvir in mixture with Copovidone 1- Sofosbuvir 2- Ledipasvir copovidone 3- Naphthalene (internal standard) Gradient elution: 1-Paracetamol 2-Phenylephrine HCl 3-Guaifensine 4-Methyl paraben sodium 5-Propyl paraben sodium qualificative and quantitative analytical method for analysis of preservative in co- trimoxazole suspension via gradient elution: 1-Sodium benzoate 2-Methyl paraben sodium

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Page 1: developed methods

Separation of antivirals using organic solvents blending technique

Ledipasvir in mixture with Copovidone 1- Sofosbuvir 2- Ledipasvir copovidone

3- Naphthalene (internal standard)

Gradient elution:

1-Paracetamol2-Phenylephrine HCl3-Guaifensine4-Methyl paraben sodium5-Propyl paraben sodium

qualificative and quantitative analytical method for analysis of preservative in co-trimoxazole suspension via gradient elution:

1-Sodium benzoate2-Methyl paraben sodium3-Propyl paraben sodium

Page 2: developed methods

Gradient method for rapid washing out interference of doxycycline after elution of principle peak:

1-EDTA disodium

Isocratic elution method for separation of Oxybutinin HCl and preservatives is syrup:

1- Methyl paraben sodium2- propyl paraben sodium 3- Oxybutinin HCl

1- Pseudoephedrine HCl2- Chlorpheniramine maleate

on C8 packing

Separation of butylated hydroxyl-touene from ointment bas after ectraction:

1- Butylated hydroxyl toluene

1- Amprolium

Page 3: developed methods

Separation of B1, B6 by ion pairing

1- Pyridoxine HCl2- Thiamine HCl

Separation of Critical pair 1, 2 with resolution Rs = 3 and K for the last peak = 8 by isocratic method

1- Lidocaine HCl2- Methyl paraben3- Triamcinolone acetonide4- Propyl paraben

1-Methoxaline2-Chlorochresol

Vitamine B12 ampoul and propyl paraben as preservative

1- Cyanocobalamine2- Propyl paraben

Page 4: developed methods

1-Caffeine2-Clorpheniramine maleate3-Dextromethorphane

GC method

1- n-butanol2-propylene glycol

GC method

Separation done by ion pairing technique and its effect on folic acid molecules:

1- Folic acid 2- Cyanocobalamine

1- Cyanocobalamine2- Folic acid

C8 packing with 10um particle size

C18 packing with 5 um particle size

Page 5: developed methods

Separation of 1,2 princple peaks on C8 packing with 10um particle size and reversed elution sequence of the same two peaks by the same mobile phase on C18 packing with 5um particle size

1- Amprolium2- Ethopabate

Qualification and quantification method for analysis of preservatives in Phyto extracts

1- Potassium sorbate 2- sodium benzoate 3- Methyl paraben sodium

Thyme extractGuava extract

Fennel extract

Eucalyptus extract

Page 6: developed methods