dermat final f2222

8/3/2019 Dermat Final f2222

1/56


2/56

CONTENTS

oIntroduction

oAim

oObjective

oMethodology

oInclusion criteriaoExclusion criteria


3/56

oData analysis and

results

oConclusion

oMerits

oDemeritsoAcknowledgement

oReference


4/56

Introduction Acne vulgaris is a chronic inflammatory disease of the

pilosebaceous units.

It is believed to be the most common disease of the

skin.

The condition usually starts in adolescence, peaks at

the ages of 14 to 19 years and frequently resolves by

mid-twenties.


5/56

Acne vulgaris develops earlier in females than in

males, which may reflect the earlier onset of pubertyin females.

The most severe forms of acne vulgaris occur more

frequently in males, but the disease tends to be more

persistent in females.


6/56

y Severity of the disease varies markedly from one

individual to the other depending upon the interplay

of various factors involved in the development of acne

vulgaris.

y Grading systems based on the clinical appearance of

lesions as well as "lesion counting" are useful in

assessing the severity of acne vulgaris.


7/56


8/56

GRADING SYSTEM

yAcne vulgaris was graded using a simple grading

system taking into account the predominant lesion to

grade acne, which classifies acne vulgaris into four

grades.


9/56

y Grade 1: Comedones, occasional papules

y

Grade 2: Papules, comedones, few pustules

y Grade 3: Predominant pustules, nodules, abscesses

y Grade 4: Mainly cysts, abscesses, widespread scarring


10/56

WHYGRADI

NG ???

y Is an important step in treating acne

yAll acne grades require different treatment

methods

y Help you to choose the most eff. Course of

treatment

y Decide if you can treat your acne at home or if

you should see your dermatologist


11/56


12/56


13/56


14/56


15/56

AIM

ySTUDY ON CLINICAL PROFILE IN 25

ACNE PATIENTS


16/56

OBJECTIVEyTo find out the relationship between

different grades of acne with

Age

Sex

Onset of lesion Duration

Site


17/56

yMenstrual cycle

ySeasonal variation

yFood

yCosmetics

yFamily history

yTreatment


18/56

METHODOLOGY The study was conducted between 5thjan 2010 and 27th

jan 2010.

All patients with acne vulgaris who consented to

participate in the study were included.

Data collected by prestructured questionnaire


19/56

The parameters evaluated included age, gender, age of

onset, duration of lesions, site of lesions, grade,

relation with menstrual cycle, family history,

treatment history ,cosmetic and food


20/56

INCLUSIONCRITERIA

yACNE PATIENTS WHO CAME TO DERMATOLOGY

OPD IN AMALA FROM 5-1-2010 TO 27-1-2010

AND WHO WERE CONSENTED TO PARTICIPATE

IN THE STUDY


21/56


22/56

PROFORMA DEMOGRAPHICVARIABLES

Name

Age

Sex

Address

OccupationHospital no

History of illness


23/56

STUDYVARIABLE

y SITE OF LESION

y ONSET OF LESION

y MENSTRUAL HISTORYy SEASONAL VARIATION

y FOOD

y COSMETICS

y HISTORY OF ACNE IN FAMILY

y TREATMENT MODALITIES ADOPTED


24/56


25/56

Gender characteristics of patients

with acne vulgaris


26/56

Age and gender characteristics of

patients with acne

Age(Years)

Male Female Total % of total

16 - 20 6 12 18 72%

21 - 25 0 7 7 28%

Total 6 19 25 100%

P value=0.55


27/56


28/56

Relationship between duration of acne

vulgaris and severity of thediseaseDuration of

acne vulgaris

(months)

Grade 1 Grade 2 Grade 3 Grade 4 Total % of

total

0 - 12 2 0 0 0 2 8%

13 - 24 5 2 0 0 7 28%

25 - 36 0 4 0 0 4 16%

37 - 48 0 4 0 0 4 16%

49 - 60 0 1 0 2 3 12%

> 60 2 1 0 2 5 20%

Total 9 12 0 4 25 100%

P value = 0.005


29/56


30/56


31/56

Duration of acne vulgaris - Genderwiseclassification

Duration of acne

vulgaris (months)

Male Female Total % of

total

0 - 12 0 2 2 8%

13 - 24 2 5 7 28%

25 - 36 3 1 4 16%

37 - 48 0 4 4 16%

49 - 60 1 2 3 12%

> 60 0 5 5 20%

Total 6 19 25 100%

P value = 0.49


32/56


33/56

Site of lesion occurrence - Genderwiseclassification

Site of LesionMale Female Total % of total

Face 6 19 25 100%

Back 3 0 3 12%

Chest 1 0 1 4%

P value = 0.4


34/56


35/56

Site of lesion occurrence - severity of thedisease

Site of Lesion Grade 1 Grade 2 Grade 3 Grade 4

Face 9 12 0 4

Back 0 2 0 1

Chest 0 2 0 0

% of total 36% 48% 0% 16%

P value = 0.4


36/56

Site of les ion occurrence - severity of the disease

9

12

4

12

0

2

4

6

8

10

12

14

Grade 1 Grade 2 Grade 3 Grade 4

Severity of disease

N

um

ber

ofr

es

ondent

Face

Back

Chest


37/56

Relation to menstrual cycle -severity of the disease

Relation to

menstrual cycle


Yes 1 0 0 1

No 7 8 0 2

Not Applicable 1 4 0 1

P value = 0.4


38/56


39/56


40/56


41/56

Relation to food - severity of the disease

Relation to food Grade 1 Grade 2 Grade 3 Grade 4

Yes 1 3 0 1

No 8 9 0 3

P value = 0.7066


42/56


43/56

Relation to usage of Cosmetics -severity of the disease

Usage of

Cosmetics


Yes 5 1 0 2

No 4 11 0 2

P value =0.049


44/56


45/56

Relation to Family History - severity ofthe disease

Family History Grade 1 Grade 2 Grade 3 Grade 4

Yes 2 10 0 3

No 7 2 0 1

P value = 0.014


46/56


47/56

Treatment undertaken - severity of thedisease

Treatment Grade 1 Grade 2 Grade 3 Grade 4

Yes 3 10 0 3

No 6 2 0 1


48/56


49/56


50/56

y OUT OF SEVERAL PARAMETERS CONSIDERED WE

GOT THREE SIGNIFICANT RESULTS

1. RELATION BETWEEN COSMETICS & GRADES OF

ACNE---------P VALUE=0.049

. DURATION IN MONTHS & GRADES OF ACNE----

------------------P VALUE=0.005

3. FAMILY HISTORY & GRADES OF ACNE------------------------------P VALUE=0.014


51/56

MERITSThe study was very much

informative.

Good interaction with patients.Experience on how to do

analysis and interpretation

It gave us an oppurtunity towork as a team.


52/56

DEMERITSy Short period of study

y Inadequate number of patients so for many

of our data p value went high

y We couldnt get any

1. patients with grade 3 acne

2. Similar study that went hand in hand withour criteria


53/56

ACKNOWLDGEMENT

We are grateful to

Dr.S. CRITONDr. SANDHYA ACHARYA

Dr. ABEL FRANCIS

Dr. ANITTA SHOJANMrs. Jinifor their guidance and help in doing this

short project


54/56

Our heartfelt gratitude to patients and their

bystanders for their cooperation

We thank our colleagues for their support

We thank library staff for their help.

Above all we thank our god almighty for

his blessings


55/56

REFERENCEy FITZ PATRICK DERMATOLOGY

y IADVL TEXT BOOK DERMATOLOGY

y http://www.ijdvl.com/article.asp?issn=0378-6323;year=2009;volume=75;issue=3;spage=272;epage=278;aulast=Adityan


56/56

dermat final f2222

Documents