department of biochemistry & molecular biology · march issue #3/spring 2017 department of...
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March Issue #3/Spring 2017
Department of Biochemistry & Molecular Biology
Kristen Solocinski, Ph.D. Graduate Student in the
Department of Biochemistry and Molecular Biolo-
gy, was selected to receive an American Physiologi-
cal Society (APS) Caroline tum Suden/Frances
Hellebrandt Professional Opportunity Award
and has been asked to present her research at the
2017 Experimental Biology meeting in Chicago, April
22-26. Her abstract is entitled, “Sex-Dependent Reg-
ulation of Blood Pressure by the Circadian Clock
Protein Per1."
Solocinski, conducting her research in Dr. Michelle
Gumz's laboratory, is among 36 men and women se-
lected from over 100 applicants.
This award, which carries a $500 prize and complimentary registration for the Ex-
perimental Biology conference, is a tribute to the role of Dr. Caroline tum Suden
and Dr. Hellebrandt's commitment to physiological research and the advancement
of women in science. Tum Suden (1900-1976) did much of her early research on
the function of the adrenal gland. Frances A. Hellebrandt (1901-1992) was a pioneer
in exercise physiology and rehabilitation and served on the editorial board of the
Journal of Applied Physiology published by APS.
The American Physiological Society (APS) is a nonprofit devoted to fostering educa-
tion, scientific research, and dissemination of information in the physiological sci-
ences. The Society was founded in 1887 with 28 members and now has over 10,500
members. Most members have doctoral degrees in physiology and/or medicine.
Congratulations, Kristen, on this significant accomplishment!
Page 2 Department of Biochemistry & Molecular Biology
The CEG serves as focal point and provides a framework to promote communication, interactions,
and collaboration among ~50 investigators in the area of epigenetics who are housed in many dif-
ferent departments within and outside of the COM. It also provides a variety of important services,
facilities, training, equipment, and expertise to assist the large number of laboratories engaged in
epigenetics-related research. In its role to enhance learning and communication in the area of epi-
genetics, the CEG organizes the CEG Seminar Program featuring special invited speakers from out-
side the University of Florida. These speakers include some of the most prominent researchers in
the field of epigenetics. This academic year, there will be eight guest speakers.
The Director for the Center for Epigenetics is Dr. Thomas P. Yang, ([email protected]). The full sched-
ule of guest speakers may be viewed HERE. These sessions are held at 4:00pm in CGRC-451A
unless stated otherwise.
March Schedule:
March 13 Paul Wade, Ph.D.
Deputy Chief and Senior Investigator
Epigenetics & Stem Cell Biology Laboratory
National Institute of Environmental Health Sciences
Research Triangle Park, NC
Topic: Transcription, chromatin and cancer
March 27 Steven Henikoff, Ph.D.
Member, Fred Hutchinson Cancer Research Center
Investigator, Howard Hughes Medical Institute
Seattle, WA
Topic: Genome-wide mapping of protein-DNA interaction dynamics
CENTER FOR EPIGENETICS
Department of Biochemistry & Molecular Biology Page 3
CENTER FOR STRUCTURAL BIOLOGY SEMINAR SERIES
The seminar series of the Center for Structural Biology seeks to provide stimulating discussions with
a molecular-structure focus or a focus on the cell and tissue/organism level of biological structure.
Dr. Mavis Agbandje-McKenna is the Director for the CSB ([email protected]).
These sessions meet the third Monday of every month in the McKnight Brain Institute, DeWeese
Auditorium (LG-101A), unless stated otherw ise. The Fall 2016-Spring 2017 schedule may be
seen HERE.
March 20 James Keck, Ph.D., Professor, Department of Biomolecular
Chemistry, University of Wisconsin School of Medicine and Public Health
Topic: Structural Mechanisms of DNA Replication Restart
April 17 Greg Bowman, Ph.D., Associate Professor, Department of Biophysics,
Johns Hopkins University, Baltimore, MD
Topic: TBA
Page 4 Department of Biochemistry & Molecular Biology
STRUCTURAL BIOLOGY JOURNAL CLUB/BCH 6875
BMB FACULTY RESEARCH DISCUSSIONS
Dr. Linda Bloom ([email protected]) coordinates this seminar series in which BMB faculty and local
researchers are able to give presentations on their ongoing research. This series meets weekly on
Wednesdays from 4:00—5:00pm. Spring 2017 full schedule.
March Schedule:
March 1 Guest Speaker, Dr. Nahum Sonenberg, Professor, Department of
CGRC-101 Biochemistry, Goodman Cancer Research Centre, University of McGill
Topic: Translational control of Fragile-X syndrome and Autism —
Related disorders via eIF4E
March 8 Spring Break
March 15 Dr. Jianrong Lu, Associate Professor, Department of Biochemistry and
ARB R3-265 Molecular Biology
Topic: Hunt for the roots of the Warburg effect in cancer
March 22 Dr. Michael Kilberg, Professor, Department of Biochemistry and
ARB R3-265 Molecular Biology
Topic: Aminoacyl-tRNA Syntheses: Transcriptional Control of a Whole
Family of Moonlighters
March 29 Dr. Robert Huigens, III, Assistant Professor, Department of
ARB R3-265 Medicinal Chemistry, College of Pharmacy
Topic: Synthetic Medicinal Chemistry Driven Discoveries
Mondays, 3:00-4:00pm, ARB R3-265
The Structural Biology Journal Club on Methodologies and Discoveries in Crystallography
and Cryo-Electron Microscopy is hosted by Dr. Mavis Agbandje-McKenna
([email protected]) and Dr. Rob McKenna ([email protected]). Click here for Spring
2017 semester schedule. (*Journal articles will be added here once they are determined—check
newsletter via BMB website frequently).
March Schedule:
March 6 Spring Break
March 13 Justin Kurian
Journal Article: TBA
March 20 Akilah Murray
Journal Article: TBA
March 27 Carrie Lomelino
Journal Article: TBA
Page 5 Department of Biochemistry & Molecular Bio logy
EPIGENETICS JOURNAL CLUB/GMS 6195
Tuesdays, 11:45am—12:45pm, ARB R3-265 Each week, a student in the Biochemistry and Molecular Biology Advanced Concentration pre-sents a journal article from the current literature to the group of BMB students, postdocs, and faculty. Senior (4th year and more advanced) students have the option of giving a research seminar or presenting a journal article. One faculty member and one or two students are as-signed as “readers” and they are available to answer questions and help with the preparation of the presentation. The readers also provide the student with feedback on the presentation to aid in the development of strong presentation skills and the ability to critically evaluate sci-entific work. This Journal Club is facilitated by Dr. Andy Berglund ([email protected]). Click here for Spring 2017 semester schedule.
March Schedule:
March 7 Spring break
March 14 Boyce Competition Presentations
March 21 Wei Zhou Faculty Reader: Dr. Bert Flanegan; Student: Nikea Pittman Article: Disordered methionine metabolism in MTAP/CDKN2A- deleted cancers leads to dependence on PRMT5: link to article
March 28 Scott Streitfeld Faculty Reader: Dr. Michael Kladde Student Readers: Justin Kurian & Jana Jenquin Article: Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses: link to article
Thursdays, 12:00–1:00pm, CGRC-351A
The Epigenetics Journal Club is facilitated by Dr. Mike Kladde ([email protected]) and Dr. Tom Yang ([email protected]). Click here for Spring 2017 semester schedule.
March Schedule:
March 2 Bihan Wang Student Readers: Joe Collins & Collin LeFrois Article: Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3; link to article
March 9 Spring Break
March 16 Aishwarya Gurumurthy Student Readers: Collin LeFrois & Bihan Wang Article: Editing DNA Methylation in the Mammalian Genome
March 23 No Meeting
March 30 Dorian Vargas-Franco Student Readers: Aishwarya Gurumurthy & Margaret White Journal Article: TBA*
BMB JOURNAL CLUB/BCH 6936
For questions or comments regarding newsletter content, please contact Teresa White, [email protected].
*Journal articles will be added here once they are determined; check back frequently.