david r. wallace, ph.d. - omics international · (endocrine and gastrointestinal pharmacology and...

David R. Wallace, Ph.D.

PERSONAL Birth date: June 28, 1960 Phone: (918) 561-1407 (office)

(918) 561-5784 (laboratory) (918) 230-8524 (cellular)

Birthplace: Detroit, Michigan FAX: (918) 561-5729

Office: Oklahoma State University Center for Health Sciences Room E-367 Department of Pharmacology & Physiology Tulsa, OK 74107-1898

Email: [email protected]

EDUCATION

1978-1983: BS, Western Michigan University,

Biomedical Sciences, Minor in Chemistry

1984-1990: Ph.D., University of Florida,

College of Pharmacy, Dept. of Pharmacodynamics, Advisor: Dr. Ralph Dawson, Jr.

Thesis: Activity and Regulation of Phosphate Activated Glutaminase: Characterization by Age and Brain

Region.

1990-1992: Postdoctoral Fellow, University of Colorado Health Science Center

College of Medicine, Dept. of Pharmacology, Advisor: Dr. Nancy Zahniser

Topic: Effect of the aging process on 2-Adrenergic receptors in rat brain.

1992-1994: Postdoctoral Fellow, University of Kentucky

College of Medicine, Dept. of Pharmacology, Advisor: Dr. Rosemarie Booze

Topic: Characterization of the D3 dopamine & psychostimulant compounds.

1995-1996: NIH Postdoctoral Fellow - Training Grant, University of Kentucky

Advisors: Drs. Phyllis Wise and Rosemarie Booze

Topic: Molecular and Cellular Aspects of Brain Aging

FACULTY EMPLOYMENT

2007-present: Professor, Dept. of Pharmacology & Physiology, Oklahoma State University Center for Health Sciences,

Tulsa, Oklahoma

D.R. Wallace CV: 30 November 2016 Page - 2 -

2013-present: Professor (Adjunct Appointment), Dept. of Forensic Sciences, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma

2002-2013: Associate Professor (Joint Appointment), Dept. of Forensic Sciences, Oklahoma State University Center

for Health Sciences, Tulsa, Oklahoma 2005-present: Adjunct Associate Professor of Pharmacology and Toxicology, Oklahoma State University, School of

Veterinary Medicine, Stillwater, Oklahoma 2001-2007: Associate Professor, Dept. of Pharmacology & Physiology, Oklahoma State University Center for Health

Sciences, Tulsa, Oklahoma. 1997-2001: Adjunct Faculty, Rogers State University, Health Sciences and Nursing Education, Claremore, Oklahoma 1996-2001: Assistant Professor, Dept. of Pharmacology & Physiology Oklahoma State University College of Osteopathic Medicine, Tulsa, Oklahoma

ADMINISTRATIVE/NON-FACULTY EMPLOYMENT

2014-present: Chief Executive Officer (CEO) of Eyra Biotechnology, Consultation and Bio-Pharma Startup Company.

Catoosa, OK. 2005-2014: Director; Center for Integrative and Applied Neuroscience, Oklahoma State University Center for Health

Sciences, Tulsa, Oklahoma [Became a regional chapter of the Society for Neuroscience] 2006-2014: Assistant Dean for Research, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma. 2006-2013: Acting Director of Research Regulatory Compliance, Oklahoma State University Center for Health

Sciences, Tulsa, Oklahoma

PROFESSIONAL SOCIETY MEMBERSHIPS Society for Neuroscience International Brain Research Organization American Society for Neurochemistry American Society for Pharmacology and Experimental Therapeutics Experimental Biology International Neurotoxicology Association Sigma Xi Society for Toxicology American Association for Laboratory Animal Science Association of University Technology Managers American Chemical Society


TEACHING EXPERIENCE Current Medical Teaching:

2013-present Instructor: 1st year Medical School fall semester PCME 8771/BIOM6771 “Biomedical Foundations Course: Part

VI” (Special topics and toxicology), Oklahoma State University Center for Health Sciences; 4 hours

2013-present Instructor: 1st year Medical School spring semester PCME8916/BIOM6910 “Neurosystems”

(Drugs/xenobiotics affecting neurodevelopment), Oklahoma State University Center for Health Sciences; 1

hours

2014-present Instructor: 2nd year Medical School fall semester PCME 8823/BIOM 6820 “Gastrointestinal/Hepatic System”

(IBD, Crohn’s, PUD, etc.), Oklahoma State University Center for Health Sciences; 4 hours

2014-present Instructor: 2nd year Medical School fall semester PCME8903/BIOM6900 “Endocrine System”

(Hypothalamus/pituitary, thyroid, estrogen pharmacology), Oklahoma State University Center for Health

Sciences; 7 hours

2015-present Instructor: 2nd year Medical School spring semester PCME8863/BIOM6860 “Reproductive System”

(Androgenic drugs/ED treatment), Oklahoma State University Center for Health Sciences; 5 hours

2016-present Instructor: 2nd year Medical School spring semester CLME8841 “Addiction Medicine” (CNS Stimulants;

Barbiturates/Benzodiazepines; Steroids and Inhalants), Oklahoma State University Center for Health

Sciences; 3 hours

Current Graduate Teaching:

2002-present Instructor: VBSC 5103 “Biochemical Toxicology”. Graduate course at OSU-Stillwater, offered in the spring

semester of alternate years - 3 hours.

2006-present Coordinator/Instructor: BIOM 6543/ITOX 6543 “Environmental Toxins and the Brain”. Graduate course at

OSU-CHS - 48 hours. (Cross-listed as part of the Interdisciplinary Toxicology program)

2014-present Instructor: BIOM 6933 “Biomedical Cornerstones” (Cellular Signaling). Graduate course at OSU-CHS,

offered each spring semester; 2 hours

2014-present Instructor: VBSC 6213 “Toxicology: Molecules to Ecosystems” (Heavy metals). Graduate Course offered at

OSU-Stillwater as part of the Interdisciplinary Toxicology Program, each fall semester; 2 hours.

2014-present Instructor: BIOM 6662 “Research Ethics and Survival Skills for the Biomedical Sciences” (Regulatory

Compliance: Biosafety, Radiation Safety and Chemical Hygiene). Graduate course at OSU-CHS, offered

each fall semester; 2 hours

Past Teaching:

1985-1990 Coordinator and Lecturer: “Anatomy/Physiology Laboratory”, University of Florida College of Pharmacy

Gainesville, Florida.

1986-1988 Lecturer: G.I. physiology, “Anatomy and Physiology” PHA-3500, College of Pharmacy, University of Florida

1992 Lecturer: “Neuropharmacology” course for Third Year Psychiatry Residents, University of Colorado Health

Sciences Center.

1995 Lecturer: “Molecular Pharmacology” course for Graduate Students, University of Kentucky, School of

Medicine.

1996-1997 Instructor: 1st year Medical School Medical Information Sciences Course, Oklahoma State University College

of Osteopathic Medicine, 2 hours.

1996-2001 Instructor: PHAR2113 “Fundamentals of Pharmacology”, Rogers University Division of Nursing and Health

Sciences (Course Coordinator), offered fall, spring and summer semesters, 141 hours total.


1996-2010 Instructor: 2nd year Medical School spring semester PE8523/BIOM5523 “Medical Pharmacology” (Endocrine

II, Autacoids, Special Topics & Central Nervous System), Oklahoma State University College of Osteopathic

Medicine, 13 hours.

1998-2002 Course coordinator/instructor: BIOM 6533 “Principles of Drug Action”. Graduate course at OSU-COM,

offered in the fall semester of even numbered years, 48 hours.

1999-2005 Course coordinator/instructor: BIOM 6543 “Neurochemistry”. Graduate course at OSU-COM, offered in

the fall semester, 48 hours.

2000-2005 Course coordinator/instructor: BIOM 6553 “Neurochemical Basis of Disease”. Graduate course at OSU-

COM, offered in the spring semester of odd numbered years: 48 hours.

2001-2005 Course coordinator/instructor: BIOM 6573 “Neurotoxicology”. Graduate course at OSU-COM, offered in

the spring semester of even numbered years: 48 hours.

2002-2008 Instructor: BIOM 6175 “Molecular and Cell Biology”. Graduate course at OSU-COM, offered in the spring

semester of alternate years, 3 hours.

2004-2005 Instructor: FRNS 6010 “Research Ethics and Statistical Design and Analysis”. Graduate Course through the

OSU-CHS Forensics Science Program - 10 hours.

2005-2008 Instructor: FRNS 5013 “Survey in Forensic Science.” Graduate course through the OSU-CHS Forensic

Science Program. Spring Semester – 2 weeks

2005-2008 Instructor: FRNS 5413 “Forensic Pathology & Medicine.” Graduate course through the OSU-CHS Forensic

Science Program. Spring Semester – 2 weeks

2005-2006 Instructor: FRNS 6010 “Techniques in Forensic Toxicology.” Graduate course through the OSU-CHS

Forensic Science Program. Summers semester – 2 hours.

2005-2007 Course coordinator/instructor: FRNS 5523 “Forensic Toxicology”. Graduate course at OSU-COM - 48 hours.

2006-2007 Instructor: FRNS 5282 “Advanced Techniques in Forensic Science”. Graduate course through the OSU-CHS

Forensic Science Program - 2 hours.

2005-2011 Course coordinator/instructor: FRNS 5533 “Drug Toxicity”. Graduate course at OSU-COM - 45 hours.

2010-2012 Instructor: BIOM 6175 “Molecular and Cellular Biology”. Graduate course at OSU-CHS – 3 hours total.

1998-2012 Instructor: 2nd year Medical School fall semester PCME8513/BIOM5513 “Medical Pharmacology”

(Respiratory/Antihistamine Pharmacology), Oklahoma State University College of Osteopathic Medicine; 8

hours

1998-2014 Instructor: 2nd year Medical School spring semester PCME8513/BIOM5513 “Medical Pharmacology”

(Endocrine and Gastrointestinal Pharmacology and Special Topics in Pharmacology), Oklahoma State

University College of Osteopathic Medicine; 21 hours

2010-2013 Instructor: BIOM 6683 and BIOM 6693 “Receptors I and II”. Graduate course at OSU-CHS – 15 hours total.

2015-present Instructor: 2nd year Medical School spring semester PCME8843/BIOM6840 “Musculoskeletal”

(Osteoporosis), Oklahoma State University Center for Health Sciences; 1 hour

COLLEGE RESEARCH/PROFESSIONAL EXPERIENCE & SERVICE

Current CHS Committee Service

2009-present: Chair, Chemical Hygiene and Radiation Use Committee, OSU-CHS

2015-present: Chair, Budget and Benefits Committee, OSU-CHS

2013-present: Member, Institutional Biosafety Committee, OSU-CHS

2006-present: Member, Research Committee, OSU-CHS


2016-2018 Vice-Chair, Group VI [Biomedical Science] Graduate faculty committee

Past CHS Committee Service

1997 Member; Pharmacology Faculty Search Committee

1997-2000 Member; Curriculum Committee

1997-2001 Member; Research Committee

1998-2003 Member; Radiation Safety Committee

1998-1999 Member; Physiology Faculty Search Committee

1999 Sergeant-At-Arms; Faculty Senate

1999-2000 Coordinator; Biomedical Science Seminar Series

2000-2002 Member; Institutional Review Board OSU-COM

2000-2001 Secretary, Faculty Senate

2000-2005 Chair; Biomedical Science Section of the Oklahoma Academy of Sciences

2000-2001 Member, Pharmacology Faculty Search Committee

2001-2004 Chair; Research Committee

2001-2002 Member; Budget and Benefits Committee

2001-2003 Member; Hazardous Materials and Equipment Committee

2001-2006 Member; Biomedical Science Graduate Committee

2001-2003 Member; Faculty Senate

2002-2003 Secretary; Faculty Senate

2002-2004 Member; Institutional Animal Use and Care Committee

2003-2004 President-Elect; Faculty Senate

2004 Member; Search Committee for Vice-President of Sponsored Programs, Research and Institutional

Development (OSU-CHS)

2004 Member; Pharmacology Faculty Search Committee

2004-2005 President; Faculty Senate

2004: Member, Search Committee for Associate Dean of Rural Health (OSU-CHS)

2005-2006: Past-President, Faculty Senate

2004-2005: Member, Integrative Marketing Team

2005-2006: Chair, Research Committee

2006-2009: Ex Officio Member, Radiation Safety Committee OSU-CHS

2006-2012: Ex Officio Member, Institutional Review Board OSU-CHS

2006-2009: Ex Officio Member, Hazardous Materials Committee OSU=CHS

2006-2008: Radiation Safety Officer, Interim (RSO), Oklahoma State University Center for Health Sciences

2007-2011: Faculty Advisor for OSU-CHS Student Osteopathic Research Association (SORA)

2009-2013: Ex Officio Member, Institutional Biosafety Committee (IBC), OSU-CHS

2007-2013 Member/Ex Officio member; Institutional Animal Use and Care Committee (IACUC), OSU-CHS

2013-2015: Chair, Institutional Biosafety Committee, OSU-CHS

NON-COLLEGE RESEARCH/PROFESSIONAL EXPERIENCE & SERVICE

1993 Life Technologies Workshop: Recombinant DNA II.

1994 Reviewer, "Pharmacology Division", Graduate Student Research Day, University of Kentucky.


1996-1997 Reviewer, “Biomedical Sciences Section”, Oklahoma Academy of Sciences. Student research

presentations.

1999-2000 Vice-Chair; Biomedical Science Section of the Oklahoma Academy of Sciences

2003-2004: Vice-Chair; Biomedical Science Section of the Oklahoma Academy of Sciences

2004-2014 OSU-CHS representative; Tulsa Research Consortium

2006-2014 Member, Biotechnology Advisory Board, Tulsa, Oklahoma

2009-2014 Founding member and Executive Board member, Tulsa Area Bioscience Education and Research

Consortium (TABERC)

2009-present Member of the “Round Table Group”, a national organization of expert witnesses

2006-2016 Member of the Tulsa Biotechnology Advisory Board

2009-present Founding member of the Autism Research Group.

2011-present Member, OKBio Postdoctoral Fellowship Training committee

2011-present Member, OKBio Programming and Development committee

2013 External Reviewer for University of South Carolina College of Pharmacy P&T committee

2013-present Executive Committee Member, Oklahoma Shared Translational Resource Center, CTSA grant awarded

through the University of Oklahoma

2014-2016 Councilor (elected); South-Central Chapter for the Society of Toxicology 2015-present Member of the “Global Mercury Working Group”, through the Society for Environmental Toxicology

and Chemistry 2015-present Member of the “Global Advisory Groups: Metals”, through the Society for Environmental Toxicology

and Chemistry 2015-present Member of the “Science Advisory Board”, Consulting and expertise affiliated organization.

CONSULTING

1993 Consultant for Williams and Associates, Memphis, TN.

2003 Consultant; Statistical consultant to Dr. Lee Rickords’ Human Genetics Laboratory OSUCHS

2004 Pharmacology/Toxicology consultant in legal custody dispute for Plaintiff: John Lambert

2005 Forensic Toxicology consultant/expert witness in capital murder case, State of Oklahoma

2005-2007 Forensic Toxicology consultant/expert witness in custody dispute

2009-present Member of the “Round Table Group”, a national organization of expert witnesses

2013-present Consult for Guidepoint Global Advisors

2014-2015 Consultant to Sarvam Solutions (Bartlesville, OK) on cancer drug development

2014 Forensic Toxicology consultant/expert witness Tulsa County [CF-2013-603]

2014 Forensic Toxicology consultant/expert witness State of Texas [6:14cv241]

2015 Author on the “Brief of Sixteen Professors of Pharmacology as Amici Curiae in Support of Neither Party”,

#14-7955 In the Supreme Court of the United States in the case of Glossip et al. (Petitioner) v. Gross

(Respondent)

2015-2016 Forensic Toxicology consultant/expert witness; 2 cases with Tulsa Public Defender’s Office

JOURNAL EDITORIAL BOARD

2011-present: Editorial Board: Journal of Clinical Toxicology

(http://www.omicsonline.org/editorialboardJCT.php)


2013-present: Editorial Board: Toxics

(http://www.mdpi.com/journal/toxics)

2013-present: Editorial Board: International Journal of Neuroscience and Behavioral Science (http://www.hrpub.org/jour_info.php?id=7)

2014-present: Editorial Board: Clinical Toxicology and Pharmacology

(http://www.enlivenarchive.org/clinical-toxicology-pharmacology.php)

2015-present: Editorial Board: Journal of Pharmacology and Clinical Research (http://juniperpublishers.com/jpcr/editorialboard.php)

EDITOR-in-CHIEF

2015-present: Editor-in-Chief: Toxicology and Forensic Medicine

(http://openventio.org/OpenJournal/ToxicologyandForensicMedicine.html)

INVITED EDITORIAL WORK FOR SPECIAL EDITIONS

Journal of Clinical Toxicology: Special Edition on Designer Drugs, Guest Editor (2014)

Toxics: Special Edition on “Developmental Neurotoxicology”, Guest Editor (2014-2015);

Website: http://www.mdpi.com/journal/toxics/special_issues/developmental-neurotoxicology

Toxics: Topical Collection "Xenobiotics in Developmental Neurotoxicity", Collection Editor (2015- ) Website: http://www.mdpi.com/journal/toxics/special_issues/xenobiotics_neurotoxicity

MANUSCRIPT REVIEWER Journal of Trace Elements and Experimental Medicine Neurobiology of Aging Synapse Neuroscience Research Communications Journal of Neuroscience Neuroscience Journal of Neurochemistry Journal of Neuroscience Research Toxicology Toxicology Letters International Journal of Molecular Sciences Journal of Clinical Toxicology Bioscience International Journal of Environmental Monitoring and Analysis American Journal of Environmental Protection Chemical Biology and Drug Design


GRANT REVIEWER

National Science Foundation

State of Texas

Cooperative Grants Program: U.S. Civilian Research and Defense Foundation

Oklahoma State University Provost Interdisciplinary Grant Program

STUDENT MENTORING

Current Students:

Jesi Whitley Major Advisor, M.S. Student, Biomedical Sciences [2015]

Matthew Green Member of Advisory Committee; Ph.D. Student, Veterinary Biomedical Science [2015]

Amie Jonckowsky Member of Advisory Committee; Ph.D. Student, Biomedical Sciences [2016]

Vikram Gujar Member of Advisory Committee; Ph.D. Student, Biomedical Sciences [2016]

Past Students:

Major Advisor:

Michele Bucholtz: D.O./Ph.D. student (until 2001, Graduated May 2005)

John Paulson: Ph.D. student (Graduated December 2005)

Summer Dodson: University of Tulsa undergraduate student, 2001 Summer Undergraduate Research Fellowship

awardee from the American Society for Pharmacology and Experimental Therapeutics

Amanda Sceiford: M.S. student Forensic Sciences (Graduated July 2004)

Elizabeth Lienneman: M.S. student, Forensic Sciences (Graduated July 2006)

Adrea Tiller: M.S. student, Forensic Sciences (Graduated July 2006)

Suzanna DeCoux: M.S. student, Forensic Sciences (Medical Withdrawal)

Emily Hackworth: M.S. Student Forensic Science (Financial Withdrawal)

Amber Hacker (Hood): M.S. student, Forensic Sciences (Graduated May 2007)

Kara Crosswy: M.S. Student, Forensic Science (Graduated December 2007)

Mikka Mooney: M.F.S.A. student, Forensic Sciences (Graduated July 2009)

Julie Payton: M.S. Student, Forensic Sciences (withdrew from program May 2010)

Summer Dodson: Ph.D. student, Biomedical Sciences (Left laboratory October 2011-Graduated July 2015)

Motunrayo Akande Fulbright Scholar from Nigeria (August 2012 – May 2013)

Thalia Douglas: D.O./M.S. Student, Biomedical Sciences (Graduated December 2013)

Dusti Sloan Ph.D. Student, Biomedical Sciences (Switched advisory committee membership, August 2013;

Graduated December 2016)

Ayantika Sen Major Advisor, Ph.D. Student, Biomedical Sciences (Left Laboratory January 2015)

Advisory Committee Member:

Connie Hebert: Ph.D. student (Graduated May 2002)

Leslie Newman: Ph.D. student (Graduated May 2000)

Heather Schafstall: M.S. student (Graduated May 2003)

Xun Song: Ph.D. student, Toxicology OSU-Stillwater (Graduated May 2003).


Janice Joslyn: M.S. student, Forensic Science (Graduated May 2004)

Kathy Williamson: Ph.D. student, Veterinary Biomedical Science OSU-Stillwater (Graduated May 2004)

Dina Miller M.S. student, Forensic Science (Graduated July 2005)

Jill Pogemiller M.S. student, Forensic Science (Graduated July 2005)

Denise Juroske: M.S. student, Forensic Sciences (Graduated May 2006)

Crystal Schulz: M.S. student, Biomedical Science (Graduated May 2006)

Jon Hart: Ph.D. student OSU-CHS (Graduated May 2006)

Sumit Ahlwalia: M.S. student, Biomedical Sciences (Graduated July 2006)

Kristin Martin: M.S. student, Biomedical Science (Graduated May 2007)

Nikita Mirajkar: Ph.D. Student, Veterinary Biomedical Science OSU-Stillwater (Graduated July 2008)

Jonathan Wilson: M.S. Student, Forensic Science (Graduated July 2008)

Demita Kinard: M.S. Student, Forensic Science (Graduated July 2008)

Susie Talbert: M.S. Student, Forensic Sciences (Graduated July 2009)

Stephanie Olofson: M.S. Student, Forensic Sciences (Graduated December 2009)

Baireddy Praveena: Ph.D. Student, Veterinary Biomedical Science OSU-Stillwater (Graduated December 2009)

Allison Veitenheimer: M.S. Student; Forensic Sciences (Graduated July 2010).

Minh Ngo: M.S. Student; Forensic Sciences (Graduated December 2010).

Catherine Worthen: M.S. Student; Forensic Sciences (Graduated July 2011).

Monica Vermillion: M.S. Student; Forensic Sciences (Graduated July 2011).

Kelly Spencer: M.S. Student; Forensic Sciences (Graduated July 2011).

Danielle Armstrong: Ph.D. Student, Biomedical Sciences (Left Program May 2012)

Laurie Ariola M.S. Student, Forensic Sciences (Graduated July 2012)

David Supeck Ph.D. Student, Biomedical Sciences (Switched advisory committee membership, August 2012)

Michelle DeGear Ph.D. Student, Biomedical Sciences (Switched advisory committee membership, August 2012)

Melissa Windham M.S. Student, Forensic Sciences (Graduated December 2013)

Julia McLouth M.S. Student, Forensic Sciences (Graduated December 2013)

Matthew Green M.S. Student, Forensic Sciences (Graduated May 2014)

Daniel Hunt M.S. Student, Forensic Sciences (Left program June 2014)

Ting Wang Ph.D. Student, Biomedical Sciences (Graduated July 2015)

Raymond Mitchell D.O./M.S. Student, Biomedical Sciences (Graduated July 2015)

Allison Veitenheimer Ph.D. Student, Veterinary Biomedical Sciences (Graduated May 2016)

Joshua Redmond Member of Advisory Committee, D.O./M.S. Student, Biomedical Sciences (Graduated July 2016)

Travis Brachtenbach Member of Advisory Committee, M.S. Student, Forensic Sciences (Graduated July 2016)

External Mentor:

Stephanie Dodson: Northeast Oklahoma State University 2003 BRIN Undergraduate Fellowship

Spencer Stanbury: Oral Roberts University undergraduate Senior Project (2003)

Whitney Allison: MS II Medical Student, OSU-CHS – Summer Research (2004)

Brad Doles: Oral Roberts University Chemistry undergraduate student (2004)

Julie Dionne: Oral Roberts University Chemistry Undergraduate (2006)

Baili Barnes Medical Student Summer Intern (summer of 2012)

Michael Payne University of Tulsa Undergraduate: TABERC Summer Intern (summer of 2012)

Edwina Thompson Tulsa Community College Biotechnology Intern (January – May 2013)


Eric Smith INBRE summer undergraduate internship (2013)

Andrea Hill Oklahoma Baptist University Summer Research Internship (2013)

Clarissa Swafford Oklahoma State University Summer Research Internship (2013)

Jonathan Nahmias INBRE summer undergraduate internship (May-July 2014)

Jesi Whitley Rogers State University Summer Research Internship (2014)

Eric Bates Tulsa Community College Biotechnology Intern (January – May 2015)

INVITED PRESENTATIONS

1990 University of Alabama at Birmingham, School of Medicine. Title: "Age-related Alterations in Phosphate-

Activated Glutaminase Activity and Regulation."

1992 University of Kentucky, Department of Pharmacology, Fall Seminar Series. Title: "Changes in 2-adrenergic

receptor density in Aged Fischer-344 rats: Effect of Chronic deprenyl treatment."

1993 University of Florida, College of Pharmacy seminar series. Title: "The D3 Dopamine Receptor in Rat Basal

Forebrain: A Possible Site of Action for Psychostimulants."

1995 Roche Bioscience, Palo Alto, CA Title: "Neural Anatomical Sites for Stimulant Action"

1995 Temple University School of Pharmacy, Philadelphia, PA Title: "The D3 Dopamine Receptor as a Neural

Substrate for Psychostimulant Abuse."

1996 Oklahoma State School of Osteopathic Medicine, Tulsa, OK Title: “IV Cocaine Administration: Relationship

between Locomotor Activity and the Dopamine D3 Receptor.”

1997 Western Michigan University, Biomedical Science Seminar Series. Title: “The Dopamine D3 Receptor as a

Novel Locus for Psychostimulant Action.”

1998 Mercer University College of Pharmacy. Title: “Modulatory and Protectant Actions of Taurine in the Rat

CNS.”

1998 Northeast Louisiana University, College of Pharmacy Title: “Iron-induced oxidation: Taurine as a

neuromodulator and protector.”

1998 Western University, College of Pharmacy Title: “Taurine Protection against Oxidative Damage in the

Rat CNS.”

1999 Co-Presenter at workshop entitled “Biological Basis of Substance Abuse” for Behavioral Services and

Community Resource Development, Inc., Tulsa, Oklahoma.

2000 American Chemical Society, Oklahoma Section, 45th Penta-sectional Meeting, "Screening of Plant and

Fungal Extracts for Neuropharmacological Activity," Belofsky, G.; Wallace, D.R., April 15, 2000,

Oklahoma State University, Stillwater, Oklahoma.

2001 Presented to the Biological Honor Society, University of Tulsa, "Natural Products Studies of the

Plant Genus Dalea," Belofsky, G.; Ekart, J.A.; French, A.N.; Dodson, S.L.; Stermitz, F.R.; Lewis, K.;

Wallace, D.R., Sept. 25.

2002 Presented at the “Aging and Ethics Conference”, Tulsa, OK, “Alternative Medicines and Aging: Boon or

Bane.” D.R. Wallace, October 11.

2004 Presented at the “Alternative Medicine in the Next Decade” Conference, Las Vegas, NV “Why Do We

Need More Research in Alternative Medicine”, D.R. Wallace, July 31, 2004.

2005 Presented at the monthly “Pediatrics Academic Day”, OSU-CHS. “Pediatric Post-operative Pain

Management”, D.R. Wallace, January 19, 2005


2005 Presented seminar, OSU College of Veterinary Medicine, “HIV Neurotoxicity: Involvement of the

Dopaminergic System” D.R. Wallace, August 25, 2005.

2006 Presented seminar, Northeastern State University, Tahlequah, OK, “AIDS-related Dementia: Involvement

of the Dopaminergic System”, D.R. Wallace, April 19, 2006.

2007 Presented Seminar, Oklahoma State University College of Veterinary Medicine, Stillwater, OK, “Low-level

Heavy Metal Exposure: Effects on the Dopaminergic System”, D.R. Wallace, November 15, 2007.

2007 Presented Seminar, Tulsa Community College, Tulsa, OK, “Mechanism and Actions of Psychostimulants”,

D.R. Wallace, November 24, 2007.

2009 Symposia Presentation, Southwestern and Rocky Mountain Region Division of American Association for

the Advancement of Science (SWARM-AAAS) 84th Annual Meeting, Tulsa OK, “Impact of Environmental

Factors on Pharmacology and Toxicology”, March 30, 2009.

2011 Interviewed by OETA for show on Autism. Discussed environmental factors in the development of autism

spectrum disorders and the current research being conducted at OSU-CHS (aired October 28, 2011;

http://www.oeta.tv/component/video/2546.html).

2012 Presented Seminar, Oklahoma State University College of Veterinary Medicine, Stillwater, OK, “Discrete

Low-level Toxin Effects on the Dopaminergic System”, D.R. Wallace, April 5, 2012.

2012 Presented Seminar, Oklahoma Defense Attorney Association Conference, Midwest City, OK, “The Science

of Drug Addiction”, D.R. Wallace, October 19, 2012.

2013 Presented Seminar, Tulsa Community College S.E. Seminar Series; Tulsa OK “Improved Living through

Chemistry: The Principles of Pharmacology, March 12, 2013.

RESEARCH FEATURES

Winter 2016 Article for the OSU-CHS Magazine: “OSU Interdisciplinary Toxicology Program Researching Impact of

Environmental Toxins on Cellular Level in Cancer Development”, page 22

SESSION CHAIR/MODERATOR & PANEL DISCUSSANT

2007-2010 Chaired and Moderated Annual Oklahoma State University Center for Health Sciences Annual Research

Day held in conjunction with the system-wide OSU Research Week.

2009 Co-Chair of “Pharmacology and Physiology in the 21st Century” Session at the Southwestern and Rocky

Mountain Region Division of American Association for the Advancement of Science (SWARM-AAAS) 84th

Annual Meeting, Tulsa OK, March 30, 2009.

2009 Panel Discussant and Presenter at the Graduate and Professional Student Government Association

(Oklahoma State University) Forum “How to Become an Effective Researcher”, Stillwater, Oklahoma,

April 15, 2009

2011 Panel Discussant and Presenter at the Tulsa Chamber of Commerce Healthcare Forum; “Research in

Tulsa”, October 13, 2011.

2012 Member of the 2012 Operating Committee for the World Toxicology Summit and Expo, September 17-19,

2012, San Antonio TX


2012 Coordinated and Co-Sponsored the OKBio ACCELERATE workshop entitled “Out of the Lab and Into the

Market”, Oklahoma State University Center for Health Sciences, Tulsa, OK, August 30, 2012.

AWARDS AND HONORS

1986 Teaching Assistant of the Year, College of Pharmacy; University of Florida.

1988 Predoctoral Award for the purchase of 28-30-month-old Fischer-344 rats (NO-AG-3-2104) National

Institutes on Aging.

1989 $250 Travel Award; Suncoast Workshop for the Neurobiology of Aging St Petersburg, Florida

1989 $250 Research Award; "Excellence in Research Award", College of Pharmacy University of Florida

1989 $4,500 Fellowship; American Foundation for Pharmaceutical Education: "George V. Doerr Memorial

Fellowship".

1989 $150 Travel Award; "Junior Scientist Travel Award" from the National Center for Toxicological Research

1989-1990 NIA Predoctoral Training Fellowship; Center for the Neurobiology of Aging, University of Florida Consists

of stipend, travel, tuition, and supply monies (AG0019601)

1990 $1,000 Research Award; "Excellence in Research Award", College of Pharmacy, University of Florida

1993 Young Scientist Travel Award, 1993 ASPET meeting, San Francisco, CA.

1995 Travel Award, attendance at the 1995 College of Physicians on Drug Dependence, Scottsdale, AZ.

2004 $3,000 American Osteopathic Association Research Council, “2004 Irvin Korr Award” for excellence in

basic science research at an Osteopathic Institution. 2004 American Osteopathic Association Meeting,

San Francisco CA, November 9, 2004.

2009 Regent’s Distinguished Research Award – Biomedical Science. Oklahoma State University Center for

Health Sciences, Tulsa, OK

2013 President’s Cup for Creative Interdisciplinarity [Third Place] – Interdisciplinary Toxicology Program.

Oklahoma State University Stillwater OK, November 2013.

CURRENT EXTRAMURAL FUNDING 2015-2017 Intramural Grant OSU-CHS, Title: “Environmental factors effecting neuronal/glial function”, (PI), Total

Cost = $35,000

PENDING EXTRAMURAL FUNDING 2017-2018 Pardee Foundation, Title: “Functionality of biologically active components from ginger as anti-breast

cancer agents”, (PI), Total cost = $117,003.

PREVIOUS EXTRAMURAL FUNDING 2014 Oklahoma IDeA Network of Biomedical Research Excellence (OK-INBRE), NIH (NCRR/NIGMS,

8P20GM103447) Title: “Summer Undergraduate Internships”, (PI), Total Cost = $2,200. 2013-2014 Intramural Toxicology Program Grant, Title: “Flavonoid Effect on Estrogen-dependent Human Breast

Cancer MCF-7 Cells”, (co-PI with Guangping Chen), Total Cost = $20,000


2011-2013 Intramural Grant OSU-CHS, Title: “Heavy metal toxicity on cellular function”, (PI), Total Cost = $15,000 2013 Oklahoma IDeA Network of Biomedical Research Excellence (OK-INBRE), NIH (NCRR/NIGMS,

8P20GM103447) Title: “Summer Undergraduate Internships”, (PI), Total Cost = $2,200. 2013-2014 Tulsa Area Bioscience Education and Research Consortium (TABERC), Title: “Biomedical Science

Internships”, (PI), Total Cost = $15,000. 2012 Intramural Grant from the Interdisciplinary Biomedical Engineering Research Initiative, Title: “Acoustic

Analysis of Whole Blood Using Micro-Resonators”, (co-PI) Total Cost = $4,000 2011-2012 Oklahoma Tobacco Research Center Seed Grant, Title: “Development of an organocatalytic and

enantioselective C-C bond forming method for the synthesis of smoking cessation agents”, (co-PI; 15% effort), Total Cost = $50,000

2011-2012 OSU Interdisciplinary Creative Planning Grant Program, Title: “Interdisciplinary Biomedical Research

Initiative: A joint program between OSU-Tulsa, CHS, and Stillwater”, PI, total cost = $20,926 2011-2012 OSU Interdisciplinary Creative Planning Grant Program, Title: “Interdisciplinary Program in Toxicology”,

PI at Center for Health Sciences and Co-PI on project, total cost = $28,353

2009-2010 NIH/NIOSH (CCT610417) T42; Title: “Dopamine-Chemokine Interactions: Target for Heavy Metals

Toxicity” (PI, 25% effort, subcontract through University of Texas-Houston and the Southwest Center for Occupational and Environmental Health SWCOEH; $7,992 total cost)

2005-2010 NIH/NIDA (DA013137-06A1), R01: Title: “HIV/Cocaine Neurotoxicity in Females” (Co-I, 10% effort; $265,900

total costs. Subcontract flow-through: Dr. Rosemarie Booze at University of South Carolina; $1,799,545 total cost)

2000-2005 NIH/NIDA. R01 (DA13137): Title: "HIV/Cocaine Neurotoxicity in Females" (Co-I, 20% effort; $192,000 total

costs. Subcontract flow-through: Dr. Rosemarie Booze, Univ. of Kentucky; $1,196,575 total costs.) – Ended 3/31/05.

2001-2003 NIH/NIDA. R15 (DA12448): Title: “Functional Evolution of Opioid Receptors.” (Co-I, 5% effort; $146,500 total

costs).

2003 BRIN Undergraduate Fellowship: Title: “Gender Differences in gp120 and Tat Neurotoxicity.” (PI, mentored Stephanie Dodson, Northeast Oklahoma State University undergraduate student; $1,500 total costs).

2002 Oklahoma EPScoR BRIN fellowship: Title: "Gender differences in gp120 and Tat neurotoxicity." (PI; $1,500 total costs).

2000 American Society of Pharmacology and Experimental Therapeutics (ASPET), SURF Award: Title: “Delta Opioid Attenuation of Oxidative Stress in SK-N-SH cells.” (PI, mentored Summer Dodson, University of Tulsa undergraduate student; $2,500 total costs).

2000-2002 NIH/NIDA. R15 (DA12448): Title: “Functional Evolution of Opioid Receptors.” (Co-I, 5% effort; $75,000 total costs).

1996-1997 Pharmacia-Upjohn. Title: “Characterization of the D3-preferring agonist, Pramipexole in rat striatum and nucleus accumbens.” (PI, $6,000)


PEER-REVIEWED PUBLICATIONS 1. R. Dawson Jr., D.R. Wallace, and S.M. Gabriel (1989) A pharmacological analysis of food intake regulation in rats treated

neonatally with monosodium-L-glutamate (MSG). Pharmacol Biochem Behav 32:391-398. DOI: 10.1016/0091-

3057(89)90168-8

2. R. Dawson Jr., J.W. Simpkins, and D.R. Wallace (1989) Age- and dose-dependent effects of neonatal monosodium

glutamate administration to female rats Neurobehav Toxicol Teratol 11:331-337. DOI: 10.1016/0892-0362(89)90003-2

3. R. Dawson Jr., D.R. Wallace, and M.J. Meldrum (1989) Endogenous glutamate release from frontal cortex of adult and

aged rats. Neurobiol. Aging, 10:665-668. DOI: 10.1016/0197-4580(89)90002-X

4. R. Dawson Jr., M.J. Meldrum, and D.R. Wallace (1989) Excitotoxin mediated neuronal loss and the regulation of

excitatory amino acid release in the aging brain. In: "Novel Approaches for the Treatment of Alzheimer's Disease":

Advances in Behavioral Biology. Pages 319-329; (E.M. Meyer and J.W. Simpkins, Eds.) Plenum Press New York)

5. R. Dawson Jr. and D.R. Wallace (1989) Central and peripheral actions of alpha2-adrenergic agonists on renal function in

Long-Evans and Brattleboro rats Pharmacology 39:240-252. DOI: 10.1159/000138604

6. R. Dawson Jr. and D.R. Wallace (1990) Neural-renal interactions in the hypertension induced by papillary necrosis: Role

of dietary NaCl intake. Pharmacology 40:42-53. DOI: 10.1159/000138638

7. R. Dawson Jr. and D.R. Wallace, and M.J. King (1990) Monoamine and amino acid content in brain regions of the

Brattleboro rat. Neurochem Res 15:755-761. DOI: 10.1007/BF00973658

8. D.R. Wallace and R. Dawson Jr. (1990) Decreased plasma taurine content in aged rats. Gerontology 36:19-27. DOI:

10.1159/000213171

9. R.J. Ulshafer, D.M. Sherry, R. Dawson Jr., and D.R. Wallace (1990) Excitatory amino acid involvement in retinal

degeneration. Brain Res 531:350-354. DOI: 10.1016/0006-8993(90)90800-Q

10. D.R. Wallace and R. Dawson Jr. (1990) Effect of age and monosodium-L-glutamate treatment on neurotransmitter

content in brain regions from male Fischer-344 rats. Neurochem Res 15:889-898. DOI: 10.1007/BF00965908

11. R. Dawson Jr. and D.R. Wallace (1992) Taurine content in tissues from aged Fischer-344 rats. AGE 15:73-81. DOI:

10.1007/BF02435005

12. D.R. Wallace and R. Dawson Jr. (1992) Ammonia regulation of phosphate-activated glutaminase displays regional

variation and impairment in the brain of aged rats. Neurochem Res 17:1113-1122. DOI: 10.1007/BF00967289

13. R. Dawson Jr and D.R. Wallace (1992) Kainic acid-induced seizures in aged rats: Neurochemical Correlates. Brain Res Bull

29:459-468. DOI: 10.1016/0361-9230(92)90083-A

14. R. Dawson Jr and D.R. Wallace (1993) Regulation of phosphate-activated glutaminase (PAG) by glutamate analogues

Neurochem Res 18:125-132. DOI: 10.1007/BF01474674

15. D.R. Wallace and R. Dawson Jr. (1993) Regional regulations of phosphate-activated glutaminase in rat brain by calcium

and phosphate: Impairment in aged rats and implication for the existence of isozymes. Neurochem Res 18:1271-1279.

DOI: 10.1007/BF00975047


16. D.R. Wallace, D.T. Muskardin and N.R. Zahniser (1994) Pharmacological characterization of 3H-idazoxan, 3H-RX821002

and para-125I-iodoclonidine binding to 2-adrenoceptors in rat cerebral cortex membranes. Eur J Pharmacol 258:67-76.

DOI: 10.1016/0014-2999(94)90058-2

17. D.R. Wallace and R. Dawson Jr. (1994) Effect of the aging process on kinetics and activity of phosphate-activated

glutaminase from various brain regions of adult and aged Fischer-344 rats. AGE 17:59-63. DOI: 10.1007/BF02434895

18. R.M. Booze and D.R. Wallace (1995) Dopamine D2 and D3 receptors in the rat striatum and nucleus accumbens: Use of

7-OH-DPAT and [125I] Iodosulpride. Synapse 19:1-13. DOI: 10.1002/syn.890190102

19. D.R. Wallace and R.M. Booze (1995) Identification of D3 and sigma receptors in the rat striatum and nucleus

accumbens using (+/-)-7-hydroxy-N,N-di-n-[3H]propyl-2-aminotetralin and carbetapentane. J Neurochem 64:700-710.

DOI: 10.1046/j.1471-4159.1995.64020700.x

20. D.R. Wallace and R.M. Booze (1995) Pramipexole, a D3-selective agonist that lacks sigma interactions in the rat brain.

Neurosci Res Comm 17:177-183.

21. D.R. Wallace, C.F. Mactutus and R.M. Booze (1996) Repeated intravenous cocaine administration: Locomotor activity

and dopamine D2/D3 receptors. Synapse 23:152-163. DOI: 10.1002/(SICI)1098-2396(199607)23:3%3C152::AID-

SYN4%3E3.0.CO;2-7

22. D.R. Wallace and R.M. Booze (1996) Dopamine D3 receptor density elevation in aged Fischer-344 X Brown Norway (F1)

rats. Eur J Pharmacol 308:283-285. DOI: 10.1016/0014-2999(96)00354-8

23. D.R. Wallace and R.M. Booze (1997) Upregulation of (+)-7-hydroxy-N,N-di-n-[3H]propylaminotetralin binding following

intracerebroventricular administration of a nitric oxide generator. Neurochem Res 22:163-170. DOI:

10.1023/A:1027311506504

24. R.M. Booze, A.F. Lehner, D.R. Wallace and C.F. Mactutus (1997) Dose response cocaine pharmacokinetics and

metabolite profile following intravenous administration and arterial sampling in unanesthetized freely moving male

rats. Neurotoxicol Teratol 19:7-15. DOI: 10.1016/S0892-0362(96)00180-8

25. P.C. Bickford, C.E. Adams, S.J. Boyson, P. Curella, G.A. Gerhardt, C. Heron, G.O. Ivy, A.M.L.Y. Lin, M.P. Murphy, K. Poth,

D.R. Wallace, D.A. Young, N.R. Zahniser, G.M. Rose (1997). Long term treatment of male F344 rats with deprenyl:

Assessment of effects on longevity, behavior, and brain function. Neurobiol Aging 18:309-318. DOI: 10.1016/S0197-

4580(97)80313-2

26. P. Green, R. Dawson Jr., D.R. Wallace and J. Owens (1998) Treatment of rat brain membranes with taurine increases

radioligand binding. Adv Exp Med Biol 442:377-383. DOI: 10.1007/978-1-4899-0117-0_47

27. D.R. Wallace, J. Owens and R.M. Booze (1998) [3H] (+) 7-OH-DPAT and [3H] Pramipexole binding in the striatum and

nucleus accumbens of Sprague-Dawley and Fischer-344 rats. Life Sci 63:PL275-PL280. DOI: 10.1016/S0024-

3205(98)00446-9

28. L.C. Newman, D.R. Wallace and C.W. Stevens (1999) Characterization of [3H]-diprenorphine binding in Rana pipiens:

Observations of filter binding enhanced by naltrexone J Pharmacol Toxicol Meth 41:43-48. DOI: 10.1016/S1056-

8719(99)00020-9

29. A.L. Coon, D.R. Wallace and R.M. Booze (1999) [3H] PN200-110 L-type calcium channel antagonist binding in the

hippocampus and cerebellum of Alzheimer’s disease Neurobiol Aging 20:597-603. DOI: 10.1016/S0197-

4580(99)00068-8


30. D.R. Wallace and R.M. Booze (2000) Sigma binding sites identified by [3H] DTG are elevated in aged Fischer-344 X

Brown-Norway (F1) rats Synapse 35:311-313. DOI: 10.1002/(SICI)1098-2396(20000315)35:4%3C311::AID-SYN9%3E3.0.CO;2-5

31. L.C. Newman, D.R. Wallace, and C.W. Stevens (2000) Selective opioid agonist and antagonist displacement of [3H]-

Naloxone binding in amphibian brain Eur J Pharmacol 397:255-262. DOI: 10.1016/S0014-2999(00)00265-X

32. L.C. Newman, D.R. Wallace, and C.W. Stevens (2000) Selective opioid agonist and antagonist competition for [3H]

naloxone binding in the amphibian spinal cord Brain Res 884:184-191. DOI: 10.1016/S0006-8993(00)02967-X

33. L.C. Newman, D.R. Wallace, and C.W. Stevens (2002) Binding characterization of selective opioids in Rana pipiens brain J

Pharm Exp Therap 301:364-370. DOI: 10.1124/jpet.301.1.364

34. G.N. Belofsky, A.F. French, D.R. Wallace, and S.L. Dodson (2004) New geranyl stilbenes from Dalea purpurea with in

vitro opioid receptor affinity J Nat Prod 67:26-30. DOI: 10.1021/np030258d

35. D.R. Wallace (2005) Overview of Molecular, Cellular and Genetic Neurotoxicology Neurol Clin North Amer 23:307-320.

DOI: 10.1016/j.ncl.2004.12.008

36. D.R. Wallace, S.L. Dodson, A Nath, and R.M. Booze (2006) Delta opioid agonists attenuate TAT1-72-induced oxidative

stress in SK-N-SH cells Neurotoxicol 27:101-107. DOI: 10.1016/j.neuro.2005.07.008

37. D.R. Wallace, S Dodson, A Nath, and R.M. Booze (2006) Estrogen attenuates gp120- and tat1-72-induced oxidative stress

and prevents loss of dopamine transporter function Synapse 59:51-60. DOI: 10.1002/syn.20214

38. J.M. Silvers, D.R. Wallace, S.B. Harrod, C.F. Mactutus, and R.M. Booze (2006) Prenatal cocaine alters dopamine and

sigma receptor binding in nucleus accumbens and striatum in dams and offspring Neurotox Teratol 28:173-180. DOI:

10.1016/j.ntt.2006.01.009

39. R.M. Booze, D.R. Wallace, J.M. Silvers, B.J. Strupp, D.M. Snow and C.F. Mactutus (2006) Prenatal cocaine exposure

alters alpha-2 receptor expression in adolescent rats BMC Neuroscience 7:33. DOI: 10.1186/1471-2202-7-33

40. D.R. Wallace (2006) HIV Neurotoxicity: Mechanisms and potential protective mechanisms J Biomed Biotech 2006:1-10.

DOI: 10.1155/JBB/2006/65741

41. J. Zhu, C.F. Mactutus, D.R. Wallace and R.M. Booze (2009) HIV-1 Tat protein-induced rapid and reversible decrease in

[3H] dopamine uptake: dissociation of [3H] dopamine uptake and [3H] WIN35,428 binding in rat striatal synaptosomes J

Pharmacol Exp Therap 329:1071-1083. DOI: 10.1124/jpet.108.150144

42. J.T. Curtis, A.N. Hood, Y. Chen, G.P. Cobb and D.R. Wallace (2010) Chronic metals ingestion by prairie voles produces

sex-specific deficits in social behavior: An animal model of autism. Behav Brain Res 213:42-49. DOI:

10.1016/j.bbr.2010.04.028

43. D.R. Wallace (2015) Current state of developmental neurotoxicology research. Toxics 3:370-372; DOI:

10.3390/toxics3040370

44. D.R. Wallace (2015) Metalloestrogen involvement in breast cancer: Implications for nanotechnology and

nanotoxicology. Toxics 3:390-413. DOI:10.3390/toxics3040390

45. D.R. Wallace and E. Bates (2015) Differential effects of organic and inorganic mercury in phenotypically variant breast

cancer cell lines. J Clin Toxicol 5:6. DOI: 10.4172/2161-0495.1000273


46. D.R. Wallace (2016) Natural products as a source of anti-cancer lead compounds: Ginger and breast cancer. J Pharmacol

Clin Res 1(3): 555564

47. D.R. Wallace and K.K. Crosswy (2016) Metabolic interactions between over-the-counter and illicit drugs at cytochrome P450 Toxicol Forensic Med (Submitted 12/2015)

48. M.G. Akande and D.R. Wallace (2016) Effects of chlorpyrifos-methyl, lead acetate and taurine on cellular function in

neuroblastoma and glioma cell lines. Toxicol In Vitro (under revision)

BOOK CHAPTERS/MONOGRAMS (invited)

Monograms

1. D.R Wallace (2005) “Acetamiprid” In: Encyclopedia of Toxicology, 2nd Edition (C. Pope, editor), Volume 1, pages 23-24.

doi:10.1016/B0-12-369400-0/00012-0

2. D.R Wallace (2005) “Dibutyl Phthalate” In: Encyclopedia of Toxicology, 2nd Edition (C. Pope, editor), Volume 2, pages 1-2.

doi:10.1016/B0-12-369400-0/00309-4

3. D.R Wallace (2005) “Phosgene Oxime” In: Encyclopedia of Toxicology, 2nd Edition (C. Pope, editor), Volume 3, page 410.

doi:10.1016/B0-12-369400-0/00759-6

4. D.R Wallace (2005) “Quinoline” In: Encyclopedia of Toxicology, 2nd Edition (C. Pope, editor), Volume 3, pages 596-597.

doi:10.1016/B0-12-369400-0/00759-6

5. D.R Wallace (2005) “Sodium Fluoroacetate” In: Encyclopedia of Toxicology, 2nd Edition (C. Pope, editor), Volume 4,

pages 62-63. doi:10.1016/B0-12-369400-0/00889-9

6. D.R Wallace (2005) “Toxaphene” In: Encyclopedia of Toxicology, 2nd Edition (C. Pope, editor), Volume 4, pages 207-209.

doi:10.1016/B0-12-369400-0/00959-5

7. D.R Wallace (2005) “Trifluralin” In: Encyclopedia of Toxicology, 2nd Edition (C. Pope, editor), Volume 4, page 388.

doi:10.1016/B0-12-369400-0/00987-X

8. Wallace, D.R., (2014). “Trifluralin”, In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition Volume 4. Elsevier Inc.,

Academic Press, pp. 846–848. doi:10.1016/B978-0-12-386454-3.00205-0

9. Wallace, D.R., (2014). “Acetamiprid”, In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition Volume 1. Elsevier Inc.,

Academic Press, pp. 30-32. doi:10.1016/B978-0-12-386454-3.00091-9

10. Wallace, D.R., (2014). “Phosgene Oxime”, In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition Volume 3. Elsevier

Inc., Academic Press, pp. 907-908. doi:10.1016/B978-0-12-386454-3.00183-4

11. Wallace, D.R., (2014). “Quinoline”, In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition Volume 4. Elsevier Inc.,


12. Wallace, D.R., (2014). “Sodium Fluoroacetate”, In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition Volume 4.

Elsevier Inc., Academic Press, pp. 331-333. doi:10.1016/B978-0-12-386454-3.00196-2

13. Wallace, D.R., (2014). “Toxaphene”, In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition Volume 4. Elsevier Inc.,


14. Wallace, D.R., (2014). “Dalapon”, In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition Volume 1. Elsevier Inc.,



Book Chapters:

15. D.R. Wallace, and A.N. Hood (2009) “Chapter 2: Cellular and Molecular Neurotoxicology: Basic Principles” In: Clinical

Neurotoxicology: Syndromes, Substances and Environments, M. Dobbs, editor, Pages 7-16.

16. D.R. Wallace, E. Lienemann, and A.N. Hood (2009) “Chapter 20: Clinical Aspects of Mercury Neurotoxicity” In: Clinical

Neurotoxicology: Syndromes, Substances and Environments, M. Dobbs, editor, Pages 251-258.

17. Wallace, D.R., (2015). Environmental pesticides and heavy metals: Role in breast cancer. In: Toxicity and Hazard of

Agrochemicals, (M.L. Larramendy and S. Soloneski, Eds.; InTech Publishers), Pages 39-70 (ISBN 978-953-51-4263-8;

http://dx.doi.org/10.5772/60779)

PUBLICATIONS IN PREPARATION

D.R. Wallace, Cysteine and Cystine reduction in [3H] dopamine uptake in rat striatum and nucleus accumbens is due to loss of transporter function Neurochem Int D.R. Wallace and A.N. Hood, Co-exposure of heavy metals and psychostimulants alter dopamine transporter (DAT) density without changes in DAT function Toxicol Lett D.R. Wallace and A.L. Sceiford, Inhibitory effects of mercuric chloride on dopamine transport in SK-N-SH cells Toxicology D.R. Wallace and J.D. Paulson Dopaminergic changes following methamphetamine co-administered with nicotinamide. D.R. Wallace and J.D. Paulson Alterations of methamphetamine metabolism by cytochrome P450 CYP2D6 isozymes when co-administered with nicotinamide D.R. Wallace. Beta-alanine acts as a potent antioxidant in SK-N-SH cells by indirect scavenging mechanisms. D.R. Wallace. Modulation of [3H] dopamine uptake by taurine and other sulfur-containing amino acids in rat striatum and nucleus accumbens D.R. Wallace and R.M. Booze Chronic intravenous cocaine upregulation of sigma receptors in the striatum is dose-dependent D.R. Wallace, R.M. Booze and C.F. Mactutus Prenatal intravenous cocaine administration upregulation of sigma receptors in rat brain is gender-selective D.R. Wallace, R.M. Booze, C.F. Mactutus and J.M. Carney Alterations in dopamine D3 receptor density in aged Fischer-344 X Brown-Norway (F1) rats: Effect of dietary restriction.

D.R. Wallace and N.R. Zahniser 2-Adrenergic receptors in the aged Fischer-344 rat brain: Region-specific reductions in p-[125I] Iodoclonidine and [3H] RX821002 but no change in autoreceptor function

ABSTRACTS

DR Wallace and R Dawson Jr (1986) Behavioral and physiological effects of monosodium-L-glutamate (MSG) on neonate rats, Southeast Nerve Net Meeting


DR Wallace, K Marks, and MJ Katovich (1986) Metabolic and physiological effects of deoxycorticosterone acetate (DOCA) and potassium chloride on DOCA/NaCl hypertension, Fed Proc 45:895

DR Wallace, SM Gabriel, and R Dawson Jr (1986) Monosodium glutamate-induced alteration in feeding behavior, blood pressure, and neuropeptide Y levels, Soc. Neurosci Abstr 12:391.17

DR Wallace and R Dawson Jr (1987) Effects of catecholamine (CA) receptor agonist and antagonists on renal dopamine (DA) levels in normotensive and hypertensive rats Fed Proc 46:6666

R Dawson Jr and D.R. Wallace (1987) Salt-induced exacerbation of bromethylamine (BEA) hypertension, Fed Proc 46:6664

D.R. Wallace and R Dawson Jr (1987) Central and peripheral actions of alpha-2 adrenergic agonists on renal function in Long-Evans (LE) and Brattleboro (DI) rats, Soc Neurosci Abstr 13:205.15.

R. Dawson Jr and DR Wallace (1987) Increased sensitivity to kainic acid-induced seizures in aged rats, Soc Neurosci Abstr 13:200.14

DR Wallace and R Dawson Jr (1988) Monosodium-L-glutamate (MSG)- and kainic acid (KA)-induced neurochemical changes in adult and aged rats, Soc Neurosci Abstr 14:168.13

MJ Meldrum, DR Wallace, and R Dawson Jr (1988) Endogenous glutamate release from frontal cortex slices from adult and aged rats, Soc Neurosci Abstr 14:403.10

R Dawson Jr and DR Wallace (1988) Central and peripheral neurotransmitter alterations in the Brattleboro (DI) rat, Soc Neurosci Abstr 14:217.21

DR Wallace and R Dawson Jr (1989) Comparison of assay parameters for the determination of phosphate-activated glutaminase (PAG) in aged rat brain, Suncoast Workshop on the Neurobiology of Aging. 1:21

DR Wallace and R Dawson Jr (1989) Alteration of activity and ammonia inhibition of phosphate-activated glutaminase from aged rat brain, Soc Neurosci Abstr 15:307.19

R Dawson Jr and DR Wallace (1989) Comparison of the binding characteristics of alpha2-adrenergic receptors in rat brain and kidney, Soc Neurosci Abstr 15:173.3

DR Wallace and R Dawson Jr (1989) Regional activity of phosphate-activated glutaminase from adult and aged male Fischer-344 rats, American Aging Association 19:29

DR Wallace and R Dawson Jr (1990) Ammonia inhibition of rat brain glutaminase: Characterization by region and age, Fed. Proc 49:3564

DM Sherry, RJ Ulshafer, R Dawson Jr and DR Wallace (1990) Levels of excitatory amino acids are elevated in RD chick photoreceptors prior to degeneration, ARVO

DR Wallace and R Dawson Jr (1990) Alterations in regional kinetics of phosphate-activated glutaminase with regards to age, Soc Neurosci Abstr 16:491.8

DR Wallace and R Dawson (1991) Regional age-related changes in ammonia regulation of phosphate-activated glutaminase (PAG), American Aging Association 21:49

DR Wallace and R Dawson (1991) Age-related alterations in both phosphate and calcium regulation of regional phosphate-activated glutaminase (PAG), American Aging Association 21:50

R Dawson Jr and DR Wallace (1991) The actions of glutamate receptor agonists and antagonists on the activity of phosphate-activated glutaminase (PAG), Soc Neurosci Abstr 17:536.6

DR Wallace and NR Zahniser (1991) Quantitative autoradiographic (QAR) comparison of 2-adrenergic receptors in rat brain regions using multiple competitors, Soc Neurosci Abstr 17:35.13


DR Wallace and NR Zahniser (1992) Localization of aging-related changes in 2-adrenergic receptors to specific brain regions of Fischer-344 rats, Soc Neurosci Abstr 18:600.3

DR Wallace and RM Booze (1993) Pharmacological characterization of [3H]7-OH-DPAT binding, a putative D3-selective radioligand, in rat basal forebrain, The Pharmacologist 35:129.6

RM Booze and DR Wallace (1993) Pharmacological characterization of binding to D1, D2 and D3 receptors in the striatum and nucleus accumbens of the rat, Soc Neurosci Abstr 19:38.12

DR Wallace and RM Booze (1993) Autoradiographic localization of dopamine D3 receptors in nucleus accumbens subregions using the putative subtype-selective radioligand [3H] 7-OH-DPAT, Soc Neurosci Abstr 19:38.13

DR Wallace and RM Booze (1994) Modulation of [3H]-(+)7-OH-DPAT binding to D3 receptors by nitric oxide in rat striatum, Dopamine 94, 2:126

DR Wallace and RM Booze (1994) Dopamine D-3 and sigma receptor ligands cross-react in rat basal forebrain, Can J. Physiol. Pharmacol 72(Suppl. 1):382

RM Booze and DR Wallace (1994) [3H]-7-OH-DPAT binds dopamine D3 and sigma1 receptors in the rat nucleus accumbens, NIDA Research Monograph 153: College on Problems of Drug Dependence 56:363

DR Wallace, CF Mactutus and RM Booze (1994) Effects of gender and prenatal I.V. cocaine on D2 and D3 receptors in the striatum and accumbens, Soc Neurosci Abstr 20:1353

RM Booze, DR Wallace, CL Colson and CF Mactutus (1994) Prenatal I.V. cocaine: Catecholamine innervation patterns and 2 receptors in the rat hippocampus, Soc Neurosci Abstr 20:597

DR Wallace, CF Mactutus and RM Booze (1995) Effects of chronic intravenous cocaine on activity and dopamine D2/D3 receptors in rat brain, NIDA Research Monograph 162: College on Problems of Drug Dependence 57:221

RM Booze, DR Wallace and CF Mactutus (1995) Sigma receptors and locomotor activity following chronic intravenous cocaine administration, NIDA Research Monograph 162: College on Problems of Drug Dependence 57:237

CF Mactutus, DR Wallace and RM Booze (1995) Chronic intravenous cocaine and hippocampal 2-adrenergic receptors: Relationship with activity and dose, NIDA Research Monograph 162: College on Problems of Drug Dependence 57:237

DR Wallace, CF Mactutus and RM Booze (1995) Pre-natal intravenous cocaine: persistent, regional alterations in 2-adrenergic receptor density, Neurotox Teratol 17:317

RM Booze, DR Wallace, MB Stonestreet, L Mendez-Arroyo, M Welch and CF Mactutus (1995) Passive cigarette smoke exposure during pregnancy: Noradrenergic-mediated alterations in adult and mid-aged offspring, Neurobehav Teratol 17:318

DR Wallace, CF Mactutus and RM Booze (1995) Acute "binge" intravenous cocaine administration elevates D3 receptor density in the rat striatum and nucleus accumbens, Soc Neurosci Abstr 21:719

RM Booze, DR Wallace and CF Mactutus (1995) Differential regulation of sigma receptor density in the rat brain following acute "binge" intravenous cocaine administration, Soc Neurosci Abstr 21:720

CL Colson, DR Wallace, CF Mactutus and RM Booze (1995) Effect of acute "binge" intravenous cocaine administration on 2-adrenergic receptor density in the rat hippocampus, Soc Neurosci Abstr 21:720

DR Wallace, CF Mactutus and RM Booze (1996) Differential alterations in D3 receptor density following acute or chronic intravenous cocaine administration in female rats, NIDA Research Monograph 163: College on Problems of Drug Dependence 58:79

DR Wallace, RM Booze and CF Mactutus (1996) Passive cigarette smoke exposure during pregnancy: Dopamine D3 receptor autoradiography in mid-aged offspring, Neurobehav Teratol 18:341


DR Wallace, CF Mactutus and RM Booze (1996) Persistent alterations in 2-adrenergic receptor density and function following prenatal IV cocaine exposure, Soc Neurosci Abstr 22:1885

B Eppler, DR Wallace, MA Pelleymounter, RM Booze, SC Liu and R Dawson Jr (1996) Taurine-Dopamine interactions in the striatum, Soc Neurosci Abstr 22:1495

DR Wallace, CF Mactutus and RM Booze (1997) Long-term noradrenergic alterations following in utero cocaine exposure, Proc Oklahoma Acad Sci 77:136

DR Wallace and M Bucholtz (1997) Possible involvement of L-DOPA as a neuromodulator at dopamine D2-like receptors, Soc Neurosci Abstr 23:1778

DR Wallace, R Dawson and J Owens (1997) Neuroprotectant actions of sulfur-containing amino acids, Proc Oklahoma Acad Sci 77:22

CW Stevens, LC Newman and DR Wallace (1998) The unireceptor hypothesis of opioid antinociception in amphibians, Soc Neurosci Abstr 24:2053

CW Stevens, LC Newman and DR Wallace (1999) The unireceptor hypothesis of opioid analgesia: Binding studies in amphibians, International Narcotics Research Conference

LC Newman, DR Wallace and CW Stevens (1999) The unireceptor hypothesis of antinociception in amphibians: Binding studies, Soc Neurosci Abstr 25:1479

DR Wallace (1999) Taurine modulation of synaptosomal [3H] dopamine uptake in rat striatum, Soc Neurosci Abstr 25:164

DR Wallace (1999) Taurine modulation of synaptosomal [3H] dopamine uptake in rat striatum, Proc Oklahoma Acad Sci 79:101

CW Stevens, LC Newman and DR Wallace (2000) From pond to pain: Amphibian opioid unireceptors and speculations on the divergence of mammalian mu, kappa, and delta opioid receptor types, College on Problems of Drug Dependence

CW Stevens, LC Newman and DR Wallace (2000) Amphibian opioid receptors: Characterization of mu, kappa, and delta opioid ligand binding, Soc Neurosci Abstr 26:434.1

CW Stevens, LC Newman and DR Wallace (2000) Binding of opioid analgesics in amphibian brain: Evidence for a single receptor type, Univ Oklahoma Research Day

CW Stevens, LC Newman and DR Wallace (2000) Mu, Kappa, and Delta opioid radioligand binding in amphibian brain, International Narcotics Research Conference

DR Wallace (2000) Modulation of [3H] dopamine uptake by HIV-related proteins, gp120 and Tat in rat striatum, Proc Oklahoma Acad Sci 81:78

JW McConnell, G Belofsky, E Levetin, DR Wallace and CW Stevens (2000) Isolation and characterization of components from biologically active extracts from a botrytis sp. of fungus, Amer Chem Soc Abstr 219:325

DR Wallace (2001) Inhibition of dopamine uptake by cysteine and related amino acids, FASEB J 15:72

CW Stevens, LC Newman, and DR Wallace (2001) Opioid receptors in amphibian brain: Radioligand binding studies, FASEB J 15:73

SL Dodson, G Belofsky and DR Wallace (2001) Screening of plant extracts for neuropharmacological activity, Amer Chemical Soc Abstr 221:270

G Belofsky, JA Ekart, AN French, SL Dodson, FR Stermitz, K Lewis and DR Wallace (2001) The biological activity and chemistry of the plant Dalea, Amer Soc Pharmacognosy Abstr


SS Sands, DR Wallace and CW Stevens (2001) Regulation of opioid receptors after chronic morphine administration in amphibians, International Narcotics Research Conference

SS Sands, DR Wallace and CW Stevens (2001) Down-regulation of opioid receptors in amphibians after chronic morphine administration, Proc Oklahoma Acad Sci 81:88

DR Wallace (2001) Attenuation of HIV-mediated oxidative stress by delta opioid receptors, Proc Oklahoma Acad Sci 81:89

JD Dentis, SL Dodson, G Belofsky and DR Wallace (2001) Natural products studies of biologically active extracts of Penicillium expansum, Midwest Regional ACS Meeting

AN French, G Belofsky and DR Wallace (2001) Isolation and characterization of natural products from neuropharmacologically active extracts of Dalea purpurea, Amer Chem Soc Abstr 221:224

DR Wallace (2001) Sulfur-containing amino acids reduce dopamine transporter function, Soc Neurosci Abstr 27:309

JG Hamra and DR Wallace (2001) Presence and characterization of the dopamine transporter in rat lymphocytes, Soc Neurosci Abstr 27:309

SS Sands, DR Wallace and CW Stevens (2001) Regulation of opioid receptors after chronic morphine administration, Soc Neurosci Abstr 27:313

NM Omara, G Belofsky and DR Wallace (2001) Neuropharmacologically active constituents of Dalea Formosa, Amer Chem Soc Abstr 222:723

DR Wallace and SL Dodson (2002) Delta opioid receptor attenuation of HIV-mediated oxidative stress, FASEB J 16:A950

SL Dodson, G Belofsky, and D Wallace (2002) Isolation and characterization of compounds from bioactive extracts of Monarda citreodora, Amer Chem Soc Abstr 223:741

AN French, G Belofsky, D Wallace and S.L. Dodson (2002) Opioid receptor-binding activity of compounds from Dalea purpurea (Fabaceae), Amer Chem Soc Abstr 223:761

K Azadi, G Belofsky, D Wallace and E Levetin (2002) Isolation of natural products from biologically active extracts of fungi, Amer Chem Soc Abstr 223:744

G Belofsky and D Wallace (2002) Biologically active products from Dalea (Fabaceae) species, Amer Chem Soc Abstr Rocky Mountain Regional Meeting

G Belofsky and D Wallace (2002) Using cellular interactions models in the analysis of chemical and biological data, Amer Chem Soc Abstr Rocky Mountain Regional Meeting

K Azadi, G Belofsky and D Wallace (2003) Isolation of fungal metabolites from biologically active extracts of Myrothecium cinctum and Gliocladium species, Amer Chem Soc Abstr 224:473

A L Sceiford and DR Wallace (2004) Effects of subtoxic mercury levels on [3H] Dopamine uptake, 5th Annual OSU Research Week

M Mooney and DR Wallace (2004) Effects of subtoxic levels of manganese on dopamine uptake in SK-N-SH cells, 5th Annual OSU Research Week

S DeCoux and DR Wallace (2004) The effect of low concentrations of 3-Nitropropionic acid on catecholamine uptake in SK-N-SH cells, 5th Annual OSU Research Week

DR Wallace, MJ Mooney and AL Sceiford (2004) Alterations in dopamine uptake by subtoxic concentrations of heavy metals, Soc Neurosci Abstr 30:345.7

G Belofsky, R Carreno and DR Wallace (2005) Biologically active phenolic metabolites of Dalea aurea (Fabaceae), Amer Chem Soc Abstr 226:760


RM Booze, MY Askenov, MV Aksenova, SB Harrod, CF Mactutus and DR Wallace (2005) Cocaine potentiates HIV-1 TAT neurotoxicity via the dopamine transporter, Soc Neuroimmune Pharmacol Abstr 11:5

DR Wallace and JD Paulson (2005) Nicotinamide-induced alterations in CYP2D6 metabolism of methamphetamine, J Neurochem 94(Suppl 1):83

DR Wallace and E Lienemann (2006) Differential effects of mercury and manganese in SK-N-SH cells, Amer J Neurochem 96(Suppl 1):103

DR Wallace and J Paulson (2006) Modification of methamphetamine’s dopaminergic effects by nicotinamide, Soc Neurosci Abstr 32:391.2

AN Hood, KA Little and DR Wallace (2007) Combined effects of heavy metals and drugs of abuse on dopamine transporter function, J Neurochem 102(Suppl 1):53

AN Hood and DR Wallace (2007) Co-exposure of heavy metals and psychostimulants alter dopamine transporter (DAT) density without changes in DAT function, Neurotoxicology Abstr 29:909

AN Hood and DR Wallace (2008) Use of surface plasmon resonance to detect alterations in human dopamine transporter function following mercury exposure, Neurotoxicology Abstr 30:863

DR Wallace and MJ Mooney (2009) Concentration- and Time-Dependent Alterations in [3H] Dopamine Uptake Following Exposure to Manganese Chloride, J Neurochem 108(Suppl 1):86-87

DR Wallace (2009) Impact of Environmental Factors on Pharmacology and Toxicology, Southwestern and Rocky Mountain Region Division of American Association for the Advancement of Science (SWARM-AAAS) 84:88

AN Hood and DR Wallace (2009) Differential effects of heavy metals on indices of dopaminergic function, Soc Neurosci Abstr 35:436.10

JT Curtis, AN Hood and DR Wallace (2009) Metals ingestion by prairie voles produces sex-specific deficits in social behavior: an animal model of autism, Soc Neurosci Abstr 35:436.11

RL Davis, JT Curtis, D Buck, AN Hood and DR Wallace (2009) Heavy metal toxicity and chemokine expression in the brain: Importance in autism, Soc Neurosci Abstr 35:436.1

RL Davis, JT Curtis, D Buck, AN Hood and DR Wallace (2010) Heavy metals and neuroimmune modulation: Importance in autism, Soc Neurosci Abstr 36:147.13

JT Curtis, Y Chen, AN Hood, and DR Wallace (2010) Developmental exposure to metals alters subsequent social behavior in mature prairie voles: a refinement of a Vole-model of autism, Soc Neurosci Abstr 36:560.10

DR Wallace and AN Hood (2010) Effects of in vivo and in vitro cadmium chloride exposure on dopamine transporter function, Soc Neurosci Abstr 36:561.14

DR Wallace, BB Barnes and AN Hood (2012) Interactions between heavy metals on neuron and glial function, Soc Neurosci Abstr 38:354.09

david r. wallace, ph.d. - omics international · (endocrine and gastrointestinal pharmacology and...

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