danish national peritonitis survey

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Danish National Peritonitis Survey James Heaf for the Danish Society of Nephrology National Registry, Herlev Hospital, University of Copenhagen

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Page 1: Danish National Peritonitis Survey

Danish National Peritonitis Survey

James Heaf for the Danish Society of Nephrology National Registry, Herlev Hospital, University of Copenhagen

Page 2: Danish National Peritonitis Survey

This Power Point presentation belongs to the Danish Renal Registry, which owns the copyright. It can be freely used for non-commercial study and educational purposes. Any commercial use or publication requires the prior permission of the Danish Renal Registry.

Page 3: Danish National Peritonitis Survey

P a t i e n t S u r v i v a l i n P e r i t o n e a l D i a l y s i s 1 9 9 0 - 2 0 0 6

9 0 - 9 5 9 5 - 0 0 2 0 0 0 -0 , 0 0 , 5 1 , 0 1 , 5 2 , 0 2 , 5 3 , 0 3 , 5 4 , 0

Y e a r s

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

Page 4: Danish National Peritonitis Survey

P D T e c h n i q u e S u r v i v a l 1 9 9 0 - 2 0 0 6

9 0 - 9 5 9 5 - 0 0 2 0 0 0 -0 , 0 0 , 5 1 , 0 1 , 5 2 , 0 2 , 5 3 , 0 3 , 5 4 , 0

Y e a r s

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

T e m p o r a r y s w i t c h e s t o H D e x c l u d e d

Page 5: Danish National Peritonitis Survey

P D T e c h n i q u e a n d P a t i e n t S u r v i v a l

9 0 - 9 5 9 5 - 0 0 2 0 0 0 -0 , 0 0 , 5 1 , 0 1 , 5 2 , 0 2 , 5 3 , 0 3 , 5 4 , 0

Y e a r s

0 , 1

0 , 2

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

Page 6: Danish National Peritonitis Survey

What happens to PD Patients?

HD 38%

Transplant 34%

Death 28%

1990-2005

Page 7: Danish National Peritonitis Survey

0

10

20

30

40

50

60

%/Y

ear

2000 2001 2002 2003 2004 2005 All

Year

Peritonitis Incidence 2000-2005

Page 8: Danish National Peritonitis Survey

Peritonitis by Center 2000-5

0 20 40 60 80

RigshospitalHerlev

HillerødRoskildeHolbæk

Nykøbing FOdense

SønderborgEsbjerg

FredericiaHolsterbro

SkejbyViborg

Aalborg

%/Year

a

b

a: 2002-5b: 2001-5

Page 9: Danish National Peritonitis Survey

L a s t P e r i t o n i t i s b e f o r e P D C e s s a t i o n

T e m p o r a r y H D

P e r m a n e n t H D0 1 2 3 4 5 6

T i m e b e f o r e P D C e s s a t i o n ( m o n t h s )

0 , 6 0

0 , 6 5

0 , 7 0

0 , 7 5

0 , 8 0

0 , 8 5

0 , 9 0

0 , 9 5

1 , 0 0

Cum

ulat

ive

Pro

port

ion

Sur

vivi

ng

D e a t h

3% of all PD patients diein relation to peritonitis.8% of all PD patients change permanently to HD in relationto peritonitis.

Page 10: Danish National Peritonitis Survey

T i m e t o 1 s t , 2 n d a n d 3 r d P e r i t o n i t i s

0 1 2 3 4

Y e a r s

0 , 2

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cum

ulat

ive

Pro

port

ion

Sur

vivi

ng

First

Second

Third

Page 11: Danish National Peritonitis Survey

T i m e b e t w e e n P e r i t o n i t i s E p i s o d e s

0 , 0 0 , 5 1 , 0 1 , 5 2 , 0 2 , 5 3 , 0

S u r v i v a l T i m e ( y e a r s )

0 , 2

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

T i m e t o 1 s t p e r i t o n i t i s

1 s t t o 2 n d P e r i t o n i t i s

2 n d t o 3 r d P e r i t o n i t i s

Page 12: Danish National Peritonitis Survey

Peritonitis Frequency/YearA l l P D C o u r s e s

0

0 - 0 , 5

0 , 5 - 1

1 - 2

2 - 3

> 3

P D C o u r s e s > 1 y e a r

0

0 - 0 , 5

0 , 5 - 1

1 - 2

2 - 3

P D C o u r s e s > 2 y e a r s

0

2 - 3

1 - 2

0 , 5 - 1

0 - 0 , 5

P D C o u r s e s > 3 Y e a r s

0

2 - 31 - 2

0 , 5 - 1

0 - 0 , 5

Page 13: Danish National Peritonitis Survey

APD vs. CAPD

0

10

20

30

40

50

60

70

%/Year

CAPD APD

56

43

Page 14: Danish National Peritonitis Survey

N o E f f e c t o f R e n a l D i a g n o s i s o nP e r i t o n i t i s - f r e e S u r v i v a l

S m a l l G N C I N P o l y c y s t i c D i a b e t i c H y p e r t e n s i v e O t h e r0 , 0 0 , 5 1 , 0 1 , 5 2 , 0

Y e a r s

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

Page 15: Danish National Peritonitis Survey

N o E f f e c t o f S e x o n P e r i t o n i t i s - f r e eS u r v i v a l

M a l e F e m a l e0 1 2 3 4

Y e a r s

0 , 0

0 , 1

0 , 2

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

Page 16: Danish National Peritonitis Survey

E f f e c t o f A g e o n P e r i t o n i t i s - f r e e S u r v i v a l

< 3 0 3 0 - 4 0 4 0 - 5 0 5 0 - 6 0 6 0 - 7 0 > 7 00 , 0 0 , 5 1 , 0 1 , 5 2 , 0

T i m e

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

p < 0 . 0 5