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33 DAFTAR PUSTAKA 1. Dan L Longo, Dennis L Kasper, J Larry Jameson, Anthony S Fauci, Stephen L Hauser, Joseph Loscalzo. Harrison’s Principles of internal medicine. USA: The McGraw-Hill Companies; 2012. 2. Undurti N Das. Insulin in Sepsis and Septic Shock. JAPI. 2003; 51:695-700. 3. Van Den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schietz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouikkon R. Intensive Insulin Therapy in Critically Ill Patients. N Engl J Med. 2001; 345: 1359-67. 4. Jonathan Cohen. The immunopathogenesis of sepsis. Nature [Internet]. 2002 [cited 2012 October 8]; 420:885-91. Available from: www.nature.com/nature . 5. F Wong, M Bernardi, R Balk, B Christman, R Moreau, G Garcia-Tsao, et al. Sepsis in cirrhosis: report on the 7 th meeting of the International Ascites Club. Gut [Internet].2005 [cited 2012 December 24]; 54:718-725. Available from: gut.bml.com. 6. Arthur C Guyton, John E Hall. Buku ajar fisiologi kedokteran. Jakarta: EGC; 2007. 7. Anselm O Agwunobi, Claire Reid, Paula Maycock, Roderick A Little, Gordon L Carlson. Insulin Resistence and Substrate Utilization in Human Endotoxemia. JCE & M. 2000; 85: 3770-3778. 8. Armella Mathonet, Alain Cariou. Glycemic Control in Sepsis. Adv Sepsis. 2007; 6(1):16-18.

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Page 1: DAFTAR PUSTAKA - eprints.undip.ac.ideprints.undip.ac.id/43754/10/DESRIYAN_PURNAMA_PUTRA_G2A009076_BAB... · DAFTAR PUSTAKA 1. Dan L Longo, Dennis L Kasper, J Larry Jameson, Anthony

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DAFTAR PUSTAKA

1. Dan L Longo, Dennis L Kasper, J Larry Jameson, Anthony S Fauci, Stephen L

Hauser, Joseph Loscalzo. Harrison’s Principles of internal medicine. USA:

The McGraw-Hill Companies; 2012.

2. Undurti N Das. Insulin in Sepsis and Septic Shock. JAPI. 2003; 51:695-700.

3. Van Den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F,

Schietz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouikkon R. Intensive

Insulin Therapy in Critically Ill Patients. N Engl J Med. 2001; 345: 1359-67.

4. Jonathan Cohen. The immunopathogenesis of sepsis. Nature [Internet]. 2002

[cited 2012 October 8]; 420:885-91. Available from: www.nature.com/nature.

5. F Wong, M Bernardi, R Balk, B Christman, R Moreau, G Garcia-Tsao, et al.

Sepsis in cirrhosis: report on the 7th

meeting of the International Ascites Club.

Gut [Internet].2005 [cited 2012 December 24]; 54:718-725. Available from:

gut.bml.com.

6. Arthur C Guyton, John E Hall. Buku ajar fisiologi kedokteran. Jakarta: EGC;

2007.

7. Anselm O Agwunobi, Claire Reid, Paula Maycock, Roderick A Little, Gordon

L Carlson. Insulin Resistence and Substrate Utilization in Human

Endotoxemia. JCE & M. 2000; 85: 3770-3778.

8. Armella Mathonet, Alain Cariou. Glycemic Control in Sepsis. Adv Sepsis.

2007; 6(1):16-18.

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34

9. Paul E Marik, Murugen Raghavan. Stress-hyperglycemia, insulin and

immunomodulation in sepsis. Intensive Care Med. 2004; 30: 748-56.

10. Alain Cariou, Christophe Vinsonneau, Jean-Francois Dhainaut. Adjunctive

therapies in sepsis: An evidence-based review. Crit Care Med.

2004;32(11):S562-S570.

11. Eric A J Hoste, Norbert H Lameire, Raymond C Vanholder, Dominique D

Benoit, Johan M A Decruyenaere, Francis A Colardyn. Acete Renal Failure in

Patients with Sepsis in a Surgical ICU: Predictive Factor, Incidence,

Comorbidity, and Outcome. J Am Soc Nephrol.2003; 14:1022-30.

12. Greg S Martin, Stephanie Eaton, Meredith Mealer, Marc Moss. Extravascular

lung water in patients with severe sepsis: a prospective cohort study. Critical

Care [Internet]. 2005 [cited 2012 December 24]; 9(2): R74-R82. Available

from: http://ccforum.com/content/9/2/R74

13. Andreas Hillenbrand, Manfred Weiss, Uwe Knippschild, Anna Maria Wolf,

Markus Huber-Lang. Sepsis-induced adipokine change with regard to insulin

resistance. International Journal of Inflamation. 2012:1-7.

14. Can Ince. The microcirculation is the motor of sepsis. Critical Care [Internet].

2005 [cited 2012 December 24]; 9(suppl 4): S13-S19. Available from:

http://ccforum.com/supplements/9/S4/S13.

15. Soren Kaeseler Andersen, Jakob Gjedsted, Christian Christiansen, Else

Tonnesen. The roles of insulin and hyperglycemia in sepsis pathogenesis.

Journal of Leukocyte Biology. 2004; 75: 413-21.

16. Abdulaziz S Aldawood, Hani M Tamim, Mohammed A Alsultan, Asgar H

Rishu, Yaseen M Arabi. Intensive insulin therapy versus conventional insulin

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therapy for critically ill trauma patients admitted to ICU. M E J Anesth

[Internet]. 2010 [cited 2013 January 24]; 20(5): 659-66. Available from:

http://www.meja.aub.edu.lb/20_5.html

17. Abbas E Kitabchi, Guillermo E Umpierrez, Mary Beth Murphy, Eugene J

Barrett, Robert A Kreisberg, Johan I Malone, et al. Management of

hyperglycaemic crises in patients with diabetes. Diabetes Care. 2001; 24: 131-

53.

18. John Koskinas, Ilias P Gomatos, Dina G Tiniakos, Nikolas Memos, Maria

Boutsikou, Aspasia Garatzioti, Athanasios Archimandritis, et al. Liver

histology in ICU patients dying from sepsis: A clinic-pathological study.

World J Gastroenterol. 2008 [Internet]. 2008 [cited 2013 January 22];

14(9):1389-93. Available from: www.wjgnwt.com

19. Herbert Spapen. Liver perfusion in sepsis, septic shock, and multiorgan

failure. The Anatomical Record [Internet]. 2008 [cited 2013 January 22];

291:714-20. Available from: Wiley Interscience.

20. Robert KM, Daryl KG, Victor WR. Biokimia harper. Jakarta: EGC; 2009.

21. Sacha Zeerleder, Erik Hack, Walter A Wuillemin. Disseminated Intravascular

Coagulation in Sepsis. CHEST [Internet]. 2005 [cited 2013 January 3];

128:2864-75. Available from: http://journal.publications.chestnet.org/

22. Frank M Brunkhorst, Christoph Engel, Frank Bloos, et al. Intensive Insulin

Therapy and Pentastarch Resuscitation in Severe Sepsis. N Engl J Med. 2008;

358: 125-39.

23. Sidharta Das, Bijay Misra. Insulin Resistance as Prognostic Indicator in Multi

Organ Dysfunction Syndrome. Medicine Update. 2011: 420-426.

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24. Ricardo Gracia Branco, Robert Charles Tasker, Pedro Celiny Ramos Gracia,

et al. Glycemic control and insulin therapy in sepsis and critical illness. Jurnal

de Pediatria. 2007; 83(Suppl 5): S128-S136.

25. Zdenek Rusavy, Vladimir Sramek, Silvie Lacigova, et al. Influence of insulin

on glucose metabolisme and energy expenditure in septic patients. Critical

Care. 2004; 8: R213-R220.

26. Tri Murti Andayani, Mohamed Izham Mihemed Ibrahim, Ahmad H Asdie.

Comparison of the glycemyc control of insulin and triple oral therapy in type 2

diabetes mellitus. Journal of Diabetes and Endocrinology. 2010: 1 (2): 13-18.

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Lampiran

Descriptive Statistics

N Minimum Maximum Mean Std. Deviation

Jenis Kelamin Pasien 22 1 2 1.41 .503

Usia Pasien 22 34 79 55.64 12.894

GDS Sebelum Pemberian

Insulin

22 100 585 279.41 130.912

GDS Sesudah Pemberian

Insulin

22 62 401 205.91 85.383

Valid N (listwise) 22

Case Processing Summary

Cases

Valid Missing Total

N Percent N Percent N Percent

GDS Sebelum Pemberian

Insulin

22 100.0% 0 .0% 22 100.0%

GDS Sesudah Pemberian

Insulin

22 100.0% 0 .0% 22 100.0%

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Jenis Kelamin Pasien

Frequency Percent Valid Percent

Cumulative

Percent

Valid Laki-laki 13 59.1 59.1 59.1

Perempuan 9 40.9 40.9 100.0

Total 22 100.0 100.0

Descriptives

Statistic Std. Error

GDS Sebelum Pemberian

Insulin

Mean 279.41 27.910

95% Confidence Interval for

Mean

Lower Bound 221.37

Upper Bound 337.45

5% Trimmed Mean 272.76

Median 280.00

Variance 17137.872

Std. Deviation 130.912

Minimum 100

Maximum 585

Range 485

Interquartile Range 215

Skewness .671 .491

Kurtosis -.184 .953

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Tests of Normality

Kolmogorov-Smirnov

a Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

GDS Sebelum Pemberian

Insulin

.144 22 .200* .945 22 .248

GDS Sesudah Pemberian

Insulin

.096 22 .200* .959 22 .476

a. Lilliefors Significance Correction

*. This is a lower bound of the true significance.

GDS Sesudah Pemberian

Insulin

Mean 205.91 18.204

95% Confidence Interval for

Mean

Lower Bound 168.05

Upper Bound 243.77

5% Trimmed Mean 203.00

Median 199.00

Variance 7290.277

Std. Deviation 85.383

Minimum 62

Maximum 401

Range 339

Interquartile Range 107

Skewness .638 .491

Kurtosis .221 .953

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Paired Samples Statistics

Mean N Std. Deviation Std. Error Mean

Pair 1 GDS Sebelum Pemberian

Insulin

279.41 22 130.912 27.910

GDS Sesudah Pemberian

Insulin

205.91 22 85.383 18.204

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Paired Samples Correlations

N Correlation Sig.

Pair 1 GDS Sebelum Pemberian

Insulin & GDS Sesudah

Pemberian Insulin

22 .839 .000

Paired Samples Test

Paired Differences

t df

Sig. (2-

tailed)

Mean

Std.

Deviation

Std. Error

Mean

95% Confidence Interval

of the Difference

Lower Upper

Pair 1 GDS Sebelum

Pemberian Insulin -

GDS Sesudah

Pemberian Insulin

73.500 75.299 16.054 40.114 106.886 4.578 21 .000

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IDENTITAS

Nama : Desriyan Purnama Putra

NIM : G2A009076

Tempat/Tanggal Lahir : Rimbo Bujang/ 23 Desember 1991

Jenis Kelamin : Laki-laki

Alamat : Jalan Bukit Kelapa Sawit VII AD 27 Tembalang

No Telepon : -

No HP : 085266923213

Email : [email protected]

Riwayat Pendidikan Formal

1. SD : SD 81/VIII Lulus Tahun: 2003

2. SMP : SMP N 3 Tebo Lulus Tahun: 2006

3. SMA : SMA N 2 Tebo Lulus Tahun: 2009

4. FK Undip : Masuk Tahun: 2009

Keanggotaan Organisasi

Anggota Maladica ( Mahasiswa Pecianta Alam Medica) FK Undip sejak 2010

Pengalaman Penelitian

Pengalaman Publikasi Tulisan Ilmiah

Pengalaman Presentasi Karya Tulis Ilmiah

Pengalaman Mengikutai Lomba Karya Ilmiah

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