cytokines and endothelial adhesion molecules (svcam-1

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Cytokines and endothelial adhesion molecules (sVCAM-1) in preeclampsia

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Page 1: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

Cytokines and endothelial adhesion molecules (sVCAM-1)

in preeclampsia

Cytokines and endothelial adhesion molecules (sVCAM-1)

in preeclampsia

Page 2: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

INTRODUCTION INTRODUCTION

Page 3: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

INTRODUCTION INTRODUCTION

Page 4: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

INTRODUCTION INTRODUCTION

The aim of the present work was to study the charac-teristics of the production of

proinflammatory and anti- inflammatory cytokines, vascular endothelial adhesion

molecule-1 (sVCAM-1) as markers of endothelial dys-function and their interactions, with varying

degrees of severity of preeclampsia.

Page 5: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

MATHERIALS AND METHODS MATHERIALS AND METHODS

Page 6: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

MATHERIALS AND METHODS MATHERIALS AND METHODS

Page 7: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

MATHERIALS AND METHODS MATHERIALS AND METHODS

Page 8: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

MATHERIALS AND METHODS MATHERIALS AND METHODS

Page 9: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

MATHERIALS AND METHODS MATHERIALS AND METHODS

Page 10: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

Page 11: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

The content of IL-1β IL-4, IL-6, IL-8, IL-10, G-GSF, TGF-β2 and sVCAM-1 in the blood serum of

pregnant surveyed groups (M ± m).

The content of IL-1β IL-4, IL-6, IL-8, IL-10, G-GSF, TGF-β2 and sVCAM-1 in the blood serum of

pregnant surveyed groups (M ± m).

Page 12: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

Page 13: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

Page 14: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

Page 15: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

Page 16: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

a significant decrease in concen-trations TGF-β2 and IL-10 in severe preeclampsia was indicated,

which may testify the exhaustion of adaptive mechanisms

Page 17: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

CONCLUSIONCONCLUSION

• In the pathogenesis of preeclampsia signifi-cant role plays development of the process of immune inflammation in the complex with endothelial dysfunction.

• These processes are shown enhanced expression of intercellular adhesion molecule and activation of the immune response in their relationship, growing to a se-vere disease process.

• In the pathogenesis of preeclampsia signifi-cant role plays development of the process of immune inflammation in the complex with endothelial dysfunction.

• These processes are shown enhanced expression of intercellular adhesion molecule and activation of the immune response in their relationship, growing to a se-vere disease process.

Page 18: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

CONCLUSIONCONCLUSION

Page 19: Cytokines and Endothelial Adhesion Molecules (sVCAM-1

THANK YOUTHANK YOU