By Patrick Nelson, Chris Rehm, and Grayson Smith

Cystic Fibrosis

How Cystic Fibrosis is Inherited

• Cystic Fibrosis is a disease that is transmitted through genes.

• It is an autosomal recessive disorder.

Carriers

• It is possible for one to be a carrier for Cystic Fibrosis.

• Cystic Fibrosis can diagnosed when one is very young.

• It is protocol for some states to test for CF on every newborn child.

Testing

• Recent studies have shown that many children who have been diagnosed with Cystic Fibrosis have had an early onset of defective bone mineralization in the lumbar spine, which is located between the ribs and pelvis. Many doctors now use this to test for Cystic Fibrosis.

Frequency of Disease

• Cystic Fibrosis (commonly known as CF), is most common in Caucasians

• Caucasians: 1 in 3,000• African-Americans: 1 in 17,000• Asian-Americans: 1 in 31,000

X-ray of lungs affected by Cystic Fibrosis

Symptoms of Cystic Fibrosis

Symptoms include:

• Body creating thick, sticky mucus that clogs the lungs and obstructs the pancreas.

• This can cause the body to become dysfunctional because these vital organs are blocked.

Treatment

• The treatments for CF include antibiotics and medication to dilate air passages in the body, chest physiotherapy, where mucus is drained from the lungs, and even lung transplantation for the most severe patients.

Example of CF Antibiotics

Prevention of CF

• Unfortunately there is no known cure for CF.• However, scientists do have a prevention that is a

prompt nutritional which prevents many of the secondary problems that occur because of malnutrition.

• These have shown improved lung function later in life of CF patients.

Works Consulted

“Early Onset of Cystic Fibrosis Studied.” Science Online. Facts on File, 2 May 5, 2, 2007. Web. 6 Feb. 2011. <http://www.fofweb.com/

Science/ default.asp?ItemID=WE40>.“Gene Modifies Cystic Fibrosis Lung Disease.” Science Online. Facts

on File, 5 Mar. 3, 5, 2009. Web. 6 Feb. 2011. <http://www.fofweb.com/ Science/ default.asp?ItemID=WE40>.

Giddings, Sharon. Cystic Fibrosis. N.p.: Chealsea House Publications, June 30, 2009. Print.

“New Cystic Fibrosis Therapy Shows Promise.” Science Online. Facts on File, 24 Sept. 9, 24, 2008. Web. 6 Feb. 2011.

<http://www.fofweb.com/ Science/ default.asp?ItemID=WE40>.Steinberg, Mark L., and Sharon D. Cosley. “Cystic Fibrosis (CF).”

Science Online. Facts on File, n.d. Web. 5 Feb. 2011. <http://www.fofweb.com/ Science/ default.asp?ItemID=WE40>.