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VALERA, ERLLYNESOSA, DIANE

REBONQUIN, MARIANEPONFERRADO, MARK ANGELO

REGULATION OFBLOOD PRESSURE

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Maintenance of Resting BloodPressure

BLOOD PRESSURE HOMEOSTASIS

Situational adjustment of BloodPressure

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Barorecetor Re!e"

#$emorecetor Re!e"

Brain %#&S'Isc$aemicResonse

Renal(Bod) *luid#ontrol

S)stem

INTERMEDIATE

LONG-TERM

BLOOD PRESSURE REGULATORYMECHANISM

#atec$olamines

Renin(Angiotensin

(AldosteroneS)stem

+asoressin

IMMEDIATE

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IntegratngCenter

Recetor

E,ectors

A,erent

E,erent

Bran Ste!"Me#$%%a

S&na% '(r#"SYMPATHETICNERVOUSSYSTEM

H)&(t*a%a!$+

Barorecetors

#$emorecetors

Heart- Blood.essels

Adrenal

medulla/#atec$olamines

0idne)/Acti.ation of

RAA s)stem

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BLOOD PRESSURE

Car#a' O$t&$t

a% Per&*era% Re++ta

CO TPR BP

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DIRECT CARDIOVASCULAREFFECTS

SYMPATHETIC TONE S)!&at*et'

($t.(/

HR

VENOCONSTRICTI

ON

ARTERIOLAR

CONSTRICTION

VENOUSRETURN

SV

CAPILLARYPRESSURE

ISFFORMATION

PLASMALOSS

CO TPR BP

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NEUROENDOCRINE EFFECTS

SYMPATHETIC TONE S)!&at*et'

($t.(/

ADRENAL

MEDULLA

0UTAGLOMERULA

R CELLS INKIDNEY

CARDIOVASCULAREFFECTS

SECERETION OFCATECHOLAMINES ACTIVATION OF

RENIN-ANGIOTENSIN-

ALDOSTERONESYSTEMVOLUMEEFFECTS

BLOOD PRESSURE

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BARORECEPTOR REFLE

Short-Term &Intermediate

Blood Pressure

Regulation

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BARORECEPTORS

ATRI

A

LO1 PRESSUREBARORE#EPTORS

+olume recetorsAtrium

HI2H PRESSUREBARORE#EPTORS

Arteries %#arotid sinus-

Aortic Arc$

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CHEMORECEPTORREFLE

Short-Term BloodPressure

Regulation

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ARTERIALCHEMORECEPTORS

BLOOD FLO1

O2 De%3er) t( t++$e+4STAGNANT HYPOIA5

CO2 $&ta6e 7r(! t++$e+

STAGNATION

BP

O2

CO2St!$%ate VMC

S)!&at*et'#+'*argeBLOODPRESSURE

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CNS ISCHAEMICRESPONSE

Short-Term BloodPressure

Regulation

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CNS ISCHAEMIC RESPONSE

BLOOD FLO1

O2 De%3er) t( t++$e+4STAGNANT HYPOIA5

CO2 $&ta6e 7r(! t++$e+

STAGNATION

BP

O2

CO2

S)!&at*et'#+'*argeBLOODPRESSURE

Cere8ra%

VMC

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RENIN-ANGIOTENSIN-

ALDOSTERONESYSTEM

IntermediateBlood PressureRegulation

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RENIN-ANGIOTENSIN-ALDOSTERONESYSTEM

Rena% Per7$+(nPre++$re

0$9tag%(!er$%ar 'e%%+ na:erent arter(%ar !$+'%e

n K#ne)

Bar(re'e&t(rRe.e9

BLOODVOLUME;PRESSUR

E

Ang(ten+n-C(n3ertngEn

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+asoconstriction

*acilitates releaseof &oreine$rine

Release of

+asoressin

Increase 1aterinta3e

Renal rea4sortionof Sodium 5 1ater

ANGIOTENSIN II

TP

R

#OBLOOD+OLUME

B

P

+ascularsmoot$muscle

S)mat$eticner.eendings

H)ot$alamus

Secretion of

ALDOSTERO&E

Adrenal#orte"

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CATECHOLAMINES

IntermediateBlood PressureRegulation

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N(re&ne&*rne

CATECHOLAMINES

= >re'e&t(r+

? re'e&t(r+

VASOCONSTRICTION

E&ne&*rne

CARDIOSTIMULATORY EFFECTS"

D(&a!ne

BLOOD PRESSURE

Automaticit) %SA &odal

Disc$arge'#onducti.it)E"cita4ilit)M)ocardial contractilit)

TPR

HR

SV

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RENAL-FLUID BLOODREGULATION

REBO&6UI&- MARIA&E

Long -TermBlood Pressure

Regulation

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1$en 4lood .olume and BP is increased-0ID&E7S e"crete e"cess !uid 4)

PRESSURE DIURESIS- Increased urine formation as a result of

increased glomerular 8ltration due to raisedrenal erfusion ressure

PRESSURE &ATRIURESIS (Increased urinar) e"cretion of sodium as a

result of increased glomerular 8ltration of

sodium due to raised renal erfusion ressure

RENAL REGULATION OF B@P

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1$en 4lood .olume and BP is DE#REASED/

Decrease glomerular caillar) H)drostaticPressure (9 Decreased 2lomerular *iltration Rate

OLI2URIA( decreased urine formation

A&URIA( renal s$utdo:n( no urine formation

RENAL REGULATION OF B@P

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RESTORATION OF FLUID VOLUME OF THE BODY BY ADH IN VOLUME DEPLETION STATE.[NTS: NUCLEUS TRACTUS SOLITARIOUS]

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SEQUENTIAL EVENTS BY !I"! IN"REASE# SALT INTA$EIN"REASES T!E ARTERIAL PRESSURE%

Increased sa! "n!a#e

Increased e$!race%ar &'%(e

Increased ar!er"a )ress%re

Decreased ren"n and an*"'!ens"n

Decreased rena re!en!"'n '+ sa! and ,a!er

Re!%rn '+ e$!race%ar &'%(e a('s! !'n'r(a

Re!%rn '+ ar!er"a ress%re a('s! !' n'r(a

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Than'ou(