curriculum vitae name: yasushi ichikawa, m.d. …yoncol/aboutus/pdf/ichikawa...scand j clin lab...
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CURRICULUM VITAE
NAME: Yasushi Ichikawa, M.D. Ph.D.
PRESENT ADDRESS:
5-11-4, Shonantakatori, Yokosuka-City, Kanagawa-Prefecture, Japan
e-mail: [email protected]
DEPARTMENT/INSTITUTION/FACILITY ADDRESS
Professor and Chairman
Yokohama City University Association of Medical Science Graduate School of
Medicine
Department of Oncology
3-9 Fukuura Kanazawa-ku, Yokohama-shi, Kanagawa, 236-0004, Japan
DATE AND PLACE OF BIRTH: May. 14, 1960; Kanagawa, Japan
Marital status: married
CITIZENSHIP: Japan
EDUCATION:
1981-1986 School of Medicine, Hokkaido University (Sapporo-city, Hokkaido, Japan)
1998 obtained M.D.（No. 302968）
1988-1993 Ph.D. course; Department of Gastroenterological Surgery, Graduate
School of Medicine ,Yokohama City University
Theme; Effect of Epidermal Growth Factor on Wound Healing of Gastric Anastomosis
1993 obtained Ph.D.（No. 243）
POSTGRADUATE EXPERIENCE:
1986-1988 Junior Resident, Okinawa Prefectural Chubu Hospital
1988-1993 General Practitioner, Department of Digestive Surgery/Liver
Transplantation Yokohama City University Hospital
1992-1993 Research Fellow, School of Medicine, University of California, Irvine
(Studying Abroad)
1993-2002 Clinical Associate, Department of Gastroenterological Surgery,
School of Medicine, Yokohama City University
2002-2005 Assistant Professor, Department of Gastroenterological Surgery,
School of Medicine, Yokohama City University
2005-2007 Clinical Director, Department of Clinical Oncology/Breast Surgery,
Yokohama City University Hospital
2007-2012 Associate Professor, Department of Clinical Oncology,
School of Medicine, Yokohama City University
2014- Professor, Chairman, Department of Oncology,
School of Medicine, Yokohama City University
LICENSE AND CERTIFICATION:
・Medical License Japanese State Examination（No. 302968）
・Board Certified Surgeon（No. 1800623）＆ Instructor（No. S007852）, Japan
Surgical Society
・Board Certified Surgeon of Gastroenterology（No. 3001060）＆ Instructor（No.
3100）, The Japanese Society of Gastroenterological Surgery
・Board Certified of the Japan Gastroenterological Endoscopy Society（No 990057）
＆ Instructor（No 990057）, Japan Gastroenterological Endoscopy Society
・Faculty（Tentative）, Subspecialty Board of Medical Oncology（No 04456）＆
Diplomate, Subspecialty Board of Medical Oncology（No 0900049）, Japanese
Society of Medical Oncology
・General Clinical Oncologist（No 10190060）＆Tentative Instructor of Clinical
Oncology, Japanese Board of Cancer Therapy
PROFESSIONAL SOCIETY:
・Japan Society of Clinical Oncology
・Japan Society of Medical Oncology
・Japanese Cancer Association
・Japan Surgical Society
・Japan Society of Gastroenterological Surgery
・Japan Gastroenterological Endoscopy Society
・Japan Surgical Association
・Japanese Society of Palliative Medicine
・The Japan Society of Coloproctology
・Japan NeuroEndocrine Tumor Society
・American Association For Cancer Research
・American Society of Clinical Oncology
CLINICAL RESEARCH EXPERIENCES
Clinical Research Experiences: 5 (Medical Products: 5, Ongoing: 2)
Major Target: Digestive Cancer
BIBLIOGRAPHY:
1. Ishikawa T, Mitsuhashi M, Ichikawa Y, Tarnawski A. (3/4) Epidermal growth factor
induces biphasic activation of ornithine decarboxylase in human stomach-derived
KATO-III cells. Life Sci. 1994;54(18):1329-34.
○2. Ichikawa Y, Tarnawski A, Sarfeh IJ, Ishikawa T, Shimada H. (1/5) Distorted
microangioarchitecture and impaired angiogenesis in gastric mucosa of portal
hypertensive rats. Gastroenterology. 1994 Mar;106(3):702-8.
3. Ichikawa Y, Mitsuhashi M, Ishikawa T, Wyle F, Chang K, Fujiwara Y, Arakawa
T, Shimada H, Tarnawski A. (1/9) Laboratory diagnosis of Helicobacter pylori infection
by polymerase chain reaction. Res Commun Mol Pathol Pharmacol. 1996,
Jan;91(1):117-28.
4. Ishikawa T, Ichikawa Y, Mitsuhashi M, Momiyama N, Chishima T, Tanaka K,
Yamaoka H, Miyazakic K, Nagashima Y, Akitaya T, Shimada H. (2/11) Matrilysin is
associated with progression of colorectal tumor. Cancer Lett. 1996 Oct 1;107(1):5-10.
5. Ichikawa Y, Ishikawa T, Momiyama N, Chishima T, Hasegawa S, Yamaoka H,
Yamamoto N, Okamoto T, Kawaguchi M, Shimada H. (1/10) Clinical application of a
novel DNA fluorescence intercalator, pyrylium dye, for the quantification of PCR
products. Scand J Clin Lab Invest. 1996 Nov;56(7):641-7.
6. Miura Y, Ichikawa Y, Ishikawa T, Ogura M, de Fries R, Shimada H, Mitsuhashi
M. (2/7) Fluorometric determination of total mRNA with oligo(dT) immobilized on
microtiter plates. Clin Chem. 1996 Nov;42(11):1758-64.
7. Ishikawa T, Ichikawa Y, Miura Y, Momiyama M, Keller C, Koo K, Akitaya T,
Shimada H, Mitsuhashi M. (2/9) Construction of cDNA bank from biopsy specimens
for
multiple gene analysis of cancer. Clin Chem. 1997 May;43(5):764-70.
8. Nagashima Y, Hasegawa S, Koshikawa N, Taki A, Ichikawa Y, Kitamura H, Misugi
K, Kihira Y, Matuo Y, Yasumitsu H, Miyazaki K. (5/11) Expression of matrilysin in
vascular endothelial cells adjacent to matrilysin-producing tumors. Int J Cancer.
1997 Jul 29;72(3):441-5.
☆9. Takeuchi N, Ichikawa Y, Ishikawa T, Momiyama N, Hasegawa S, Nagashima Y,
Miyazaki K, Koshikawa N, Mitsuhashi M, Shimada H.(2/10) Matrilysin gene
expression in sporadic and familial colorectal adenomas. Mol Carcinog. 1997
Aug;19(4):225-9.
10. Ishikawa T, Ichikawa Y, Tarnawski A, Fujiwara Y, Fukuda T, Arakawa T,
Mitsuhashi M, Shimada H. (2/8) Indomethacin interferes with EGF-induced activation
of ornithine decarboxylase in gastric cancer cells. Digestion. 1998;59(1):47-52.
○11. Ichikawa Y, Ishikawa T, Momiyama N, Yamaguchi S, Masui H, Hasegawa S,
Chishima T, Takimoto A, Kitamura H, Akitaya T, Hosokawa T, Mitsuhashi M,
Shimada H. (1/13) Detection of regional lymph node metastases in colon cancer by
using RT-PCR
for matrix metalloproteinase 7, matrilysin. Clin Exp Metastasis. 1998 Jan;16(1):3-8.
12. Momiyama N, Koshikawa N, Ishikawa T, Ichikawa Y, Hasegawa S, Nagashima Y,
Mitsuhashi M, Miyazaki K, Shimada H.(4/9) Inhibitory effect of matrilysin antisense
oligonucleotides on human colon cancer cell invasion in vitro. Mol Carcinog. 1998
May;22(1):57-63.
13. Hasegawa S, Koshikawa N, Momiyama N, Moriyama K, Ichikawa Y, Ishikawa T,
Mitsuhashi M, Shimada H, Miyazaki K.(5/9) Matrilysin-specific antisense
oligonucleotide inhibits liver metastasis of human colon cancer cells in a nude
mouse model. Int J Cancer. 1998 Jun 10;76(6):812-6.
☆14. Miura Y, Ichikawa Y, Ishikawa T, Sekido H, Nakano A, Mitsuhashi M, Shimada
(2/7) H. The elevated mRNA content as a potential indicator of precancerous states of
the gallbladder mucosa in patients with pancreaticobiliary maljunction. Oncol Rep.
1998 Jul-Aug;5(4):845-51.
15. Takabe K, Ohki S, Kunihiro O, Sakashita T, Endo I, Ichikawa Y, Sekido H,
Amano T, Nakatani Y, Suzuki K, Shimada H.(6/11) Anisakidosis: a cause of intestinal
obstruction from eating sushi. Am J Gastroenterol. 1998 Jul;93(7):1172-3.
16. Akiyama H, Yamaoka H, Tanaka K, Ishikawa T, Ichikawa Y, Wakasugi J,
Nagashima Y, Shimada H. (5/8) Continuous hyperthermic peritoneal perfusion for
peritoneal dissemination of gastric cancer. Hepatogastroenterology. 1998 Nov-
Dec ;45(24):2079-86.
17. Miyazaki K, Koshikawa N, Hasegawa S, Momiyama N, Nagashima Y, Moriyama
K,
Ichikawa Y, Ishikawa T, Mitsuhashi M, Shimada H. (7/10) Matrilysin as a target for
chemotherapy for colon cancer: use of antisense oligonucleotides as antimetastatic
agents. Cancer Chemother Pharmacol. 1999;43 Suppl:S52-5.
18. Tanaka K, Togo S, Nanko M, Ishikawa T, Ichikawa Y, Yamaoka H, Shimada
H.(5/7)
Sialyl Lewis X expression in vascular permeating lesions as a factor for predicting
colorectal cancer metastasis. Hepatogastroenterology. 1999 Mar-Apr;46(26):875-82.
☆19. Kameda K, Shimada H, Ishikawa T, Takimoto A, Momiyama N, Hasegawa S,
Misuta K, Nakano A, Nagashima Y, Ichikawa Y. (10/10) Expression of highly
polysialylated neural cell adhesion molecule in pancreatic cancer neural invasive lesion.
Cancer Lett. 1999 Apr 1;137(2):201-7.
20. Ishikawa T, Ikeda I, Momiyama N, Yamaoka H, Ishiyama A, Chishima T, Ichikawa
Y, Kitamura H, Shuin T, Shimada H. (7/10) Genetic instability did not lead to p53
mutations in an extremely early-onset breast cancer in a cancer-prone family. Jpn
J Clin Oncol. 1999 Jul;29(7):332-5.
21. Takabe K, Lebrun JJ, Nagashima Y, Ichikawa Y, Mitsuhashi M, Momiyama N,
Ishikawa T, Shimada H, Vale WW. (4/9) Interruption of activin A autocrine regulation
by
antisense oligodeoxynucleotides accelerates liver tumor cell proliferation.
Endocrinology. 1999 Jul;140(7):3125-32.
22. Ishikawa T, Kamiyama M, Hisatomi H, Ichikawa Y, Momiyama N, Hamaguchi Y,
Hasegawa S, Narita T, Shimada H. (4/9) Telomerase enzyme activity and RNA
expression in adriamycin-resistant human breast carcinoma MCF-7 cells. Cancer Lett.
1999 Jul 1;141(1-2):187-94.
23. Miyamoto H, Miyagi Y, Ishikawa T, Ichikawa Y, Hosaka M, Kubota Y. (4/6) DNA
polymerase beta gene mutation in human breast cancer. Int J Cancer. 1999 Nov
26;83(5):708-9.
24. Tarnawski A, Arakawa T, Sekhon S, Ichikawa Y, Szabo I, Sarfeh IJ. (4/6) Isolation
of morphologically and functionally intact gastric mucosal microvessels rapid
communication. J Physiol Pharmacol. 2000 Mar;51(1):167-75.
○25. Ichikawa Y, Koshikawa N, Hasegawa S, Ishikawa T, Momiyama N, Kunizaki C,
Takahashi M, Moriwaki Y, Akiyama H, Yamaoka H, Yanoma S, Tsuburaya A,
Nagashima Y, Shimada H, Miyazaki K. (1/15) Marked increase of trypsin(ogen) in
serum of linitis plastica (gastric cancer, borrmann 4) patients. Clin Cancer Res. 2000
Apr;6(4):1385-8.
☆26. Hosaka N, Ichikawa Y, Ishikawa T, Nagashima Y, Kunisaki C, Takahashi M,
Moriwaki Y, Akiyama H, Yamaguchi S, Ota M, Ooki S, Ike H, Shimada H. (2/13)
Correlation of immunohistochemical p53 labeling index with inhibition rate in
chemosensitivity test in gastric and colon cancer. Anticancer Res. 2001
Jan-Feb;21(1A):229-35.
27. Ishikawa T, Kamiyama M, Tani-Ishii N, Suzuki H, Ichikawa Y, Hamaguchi Y,
Momiyama N, Shimada H.(5/8) Inhibition of osteoclast differentiation and bone
resorption by cathepsin K antisense oligonucleotides. Mol Carcinog. 2001
Oct;32(2):84-91.
☆28. Nishizuka I, Ichikawa Y, Ishikawa T, Kamiyama M, Hasegawa S, Momiyama N,
Miyazaki K, Shimada H. (2/8) Matrilysin stimulates DNA synthesis of cultured vascular
endothelial cells and induces angiogenesis in vivo. Cancer Lett. 2001 Nov 28;
173(2):175-82.
29. Morita T, Togo S, Kubota T, Kamimukai N, Nishizuka I, Kobayashi T, Ichikawa
Y, Ishikawa T, Takahashi S, Matsuo K, Tomaru Y, Okazaki Y, Hayashizaki Y,
Shimada
H. (7/14) Mechanism of postoperative liver failure after excessive hepatectomy
investigated using a cDNA microarray. J Hepatobiliary Pancreat Surg. 2002;9(3):352-9.
30. Nishizuka I, Ishikawa T, Hamaguchi Y, Kamiyama M, Ichikawa Y, Kadota K, Miki
R, Tomaru Y, Mizuno Y, Tominaga N, Yano R, Goto H, Nitanda H, Togo S, Okazaki
Y,
Hayashizaki Y, Shimada H. (5/17) Analysis of gene expression involved in brain
metastasis from breast cancer using cDNA microarray. Breast Cancer. 2002;9(1):26-32.
31. Ishikawa T, Hamaguchi Y, Ichikawa Y, Shimura M, Kawano N, Nakatani Y,
Ohnishi
H, Maegawa J, Ogino I, Shimada H. (3/10) Locally advanced mucinous carcinoma of
the
breast with sudden growth acceleration: a case report. Jpn J Clin Oncol. 2002
Feb;32(2):64-7.
○32. Kamiyama M, Ichikawa Y, Ishikawa T, Chishima T, Hasegawa S, Hamaguchi Y,
Nagashima Y, Miyagi Y, Mitsuhashi M, Hyndman D, Hoffman RM, Ohki S, Shimada
H.(2/13) VEGF receptor antisense therapy inhibits angiogenesis and peritoneal
dissemination of human gastric cancer in nude mice. Cancer Gene Ther. 2002
Feb;9(2):197-201.
33. Togo S, Akiyama H, Yamaguchi S, Ichikawa Y, Ike H, Shimada H. (4/6) Clinical
evaluation of granisetron as an inhibitor of nausea and vomiting induced by oral
anticancer drugs. Oncol Rep. 2002 Mar-Apr;9(2):277-82.
○☆34. Huo N, Ichikawa Y, Kamiyama M, Ishikawa T, Hamaguchi Y, Hasegawa S,
Nagashima Y, Miyazaki K, Shimada H. (2/9) MMP-7 (matrilysin) accelerated growth
of human umbilical vein endothelial cells. Cancer Lett. 2002 Mar 8;177(1):95-100.
35. Ike H, Shimada H, Ohki S, Togo S, Yamaguchi S, Ichikawa Y. (6/6) Results of
aggressive resection of lung metastases from colorectal carcinoma detected by
intensive follow-up. Dis Colon Rectum. 2002 Apr;45(4):468-73; discussion 473-5.
○36. Ichikawa Y, Ishikawa T, Takahashi S, Hamaguchi Y, Morita T, Nishizuka I,
Yamaguchi S, Endo I, Ike H, Togo S, Oki S, Shimada H, Kadota K, Nakamura S, Goto
H, Nitanda H, Satomi S, Sakai T, Narita I, Gejyo F, Tomaru Y, Shimizu K,
Hayashizaki Y, Okazaki Y. (1/24) Identification of genes regulating colorectal
carcinogenesis by using the algorithm for diagnosing malignant state method.
Biochem Biophys Res Commun. 2002 Aug 16;296(2):497-506.
37. Ike H, Shimada H, Togo S, Yamaguchi S, Ichikawa Y, Tanaka K. (5/6) Sequential
resection of lung metastasis following partial hepatectomy for colorectal cancer.
Br J Surg. 2002 Sep;89(9):1164-8.
38. Sakakura C, Hagiwara A, Nakanishi M, Shimomura K, Takagi T, Yasuoka R, Fujita
Y, Abe T, Ichikawa Y, Takahashi S, Ishikawa T, Nishizuka I, Morita T, Shimada H,
Okazaki Y, Hayashizaki Y, Yamagishi H. (9/13) Differential gene expression profiles of
gastric cancer cells established from primary tumour and malignant ascites. Br J
Cancer. 2002 Nov 4;87(10):1153-61.
39. Morioka D, Kubota T, Sekido H, Matsuo K, Saito S, Ichikawa Y, Endo I, Togo S,
Shimada H. (6/9) Prostaglandin E1 improved the function of transplanted fatty liver in
a rat reduced-size-liver transplantation model under conditions of permissible
cold preservation. Liver Transpl. 2003 Jan;9(1):79-86.
☆40. Miura M, Ichikawa Y, Tanaka K, Kamiyama M, Hamaguchi Y, Ishikawa T,
Yamaguchi S, Togo S, Ike H, Ooki S, Shimada H. (2/11) Real-time PCR (TaqMan
PCR) quantification of carcinoembryonic antigen (CEA) mRNA in the peripheral blood
of colorectal cancer patients. Anticancer Res. 2003 Mar-Apr;23(2B):1271-6.
41. Ike H, Shimada H, Yamaguchi S, Ichikawa Y, Fujii S, Ohki S. (4/6) Outcome of
total
pelvic exenteration for primary rectal cancer. Dis Colon Rectum. 2003 Apr;46(4):474-
80.
42. Ike H, Shimada H, Ohki S, Yamaguchi S, Ichikawa Y, Fujii S. (5/6) Outcome of
total
pelvic exenteration for locally recurrent rectal cancer. Hepatogastroenterology. 2003
May-Jun;50(51):700-3.
☆43. Ding J, Ichikawa Y, Ishikawa T, Shimada (2/4) H. Effect of formalin on
extraction
of mRNA from a formalin-fixed sample: a basic investigation. Scand J Clin Lab
Invest. 2004;64(3):229-35.
43. Ichikawa Y, Kamiyama M, Sekido H, Ishikawa T, Miura Y, Kamiya N, Morita T,
Shimada H. (1/8) Telomerase activity and Bcl-2 expression in gallbladders of
pancreaticobiliary maljunction patients: a preliminary study. J Hepatobiliary
Pancreat Surg. 2004;11(1):34-9.
44. Ota M, Shimada H, Masui H, Tanaka K, Yamaguchi S, Ichikawa Y, Togo S, Ike H,
Oki S. (6/9) Adjuvant hepatic arterial infusion chemotherapy after curative resection
for Dukes C colorectal cancer: a pilot study. Hepatogastroenterology. 2004
Jan-Feb;51(55):124-7.
45. Shimizu D, Ishikawa T, Ichikawa Y, Togo S, Hayasizaki Y, Okazaki Y, Shimada
(3/7)
H. Current progress in the prediction of chemosensitivity for breast cancer.
Breast Cancer. 2004;11(1):42-8
46. Togo S, Makino H, Kobayashi T, Morita T, Shimizu T, Kubota T, Ichikawa Y,
Ishikawa T, Okazaki Y, Hayashizaki Y, Shimada H. (7/11) Mechanism of liver
regeneration after partial hepatectomy using mouse cDNA microarray. J Hepatol. 2004
Mar;40(3):464-71.
47. Shimada H, Tanaka K, Masui H, Nagano Y, Matsuo K, Kijima M, Ichikawa Y, Ike
H, Ooki S, Togo S. (7/10) Results of surgical treatment for multiple (> or =5 nodules)
bi-lobar hepatic metastases from colorectal cancer. Langenbecks Arch Surg. 2004
Apr;389(2):114-21.
48. Nagano Y, Nagahori K, Yoshiro F, Hamaguchi Y, Ishikawa T, Ichikawa Y, Togo S,
Okazaki Y, Hayashizaki Y, Shimada H. (6/10) Gene expression profile analysis of
regenerating liver after portal vein ligation in rats by a cDNA microarray
system. Liver Int. 2004 Jun;24(3):253-8.
49. Ueda M, Miura Y, Kunihiro O, Ishikawa T, Ichikawa Y, Endo I, Sekido H, Togo
S, Shimada H. (5/9) MUC1 overexpression is the most reliable marker of invasive
carcinoma in intraductal papillary-mucinous tumor (IPMT). Hepatogastroenterology.
2005 Mar-Apr;52(62):398-403.
50. Yamagishi S, Shimada H, Ishikawa T, Fujii S, Tanaka K, Masui H, Yamaguchi S,
Ichikawa Y, Togo S, Ike H. (8/10) Expression of dihydropyrimidine dehydrogenase,
thymidylate synthase, p53 and p21 in metastatic liver tumor from colorectal
cancer after 5-fluorouracil-based chemotherapy. Anticancer Res. 2005
Mar-Apr;25(2B):1237-42.
51. Kijima M, Togo S, Ichikawa Y, Miura M, Yamagishi S, Matsuo K, Tanaka K,
Masui
H, Ishikawa T, Ike H, Shimada H. (3/11) Clinical significance of serum CEA protein
and
CEA mRNA after resection of colorectal liver metastases. Anticancer Res. 2005
Mar-Apr;25(2B):1327-32.
52. Matsuo K, Togo S, Sekido H, Morita T, Kamiyama M, Morioka D, Kubota T, Miura
Y, Tanaka K, Ishikawa T, Ichikawa Y, Endo I, Goto H, Nitanda H, Okazaki Y,
Hayashizaki Y, Shimada H. (11/17)Pharmacologic preconditioning effects:
prostaglandin E1 induces heat-shock proteins immediately after ischemia/reperfusion of
the mouse
liver. J Gastrointest Surg. 2005 Jul-Aug;9(6):758-68.
53. Ishikawa T, Yoshida S, Sekido H, Morioka D, Akiyama H, Ichikawa Y, Endo I,
Masunari H, Togo S, Kobayashi H, Shimada H.(6/11) Biliobiliary fistulas manifested
by
worsening liver function a case report. Hepatogastroenterology. 2005 Jul-Aug; 52(64):
1092-4.
54. Shimizu D, Ishikawa T, Ichikawa Y, Togo S, Hayasizaki Y, Okazaki Y, Danenberg
PV, Shimada H. (3/8) Prediction of chemosensitivity of colorectal cancer to 5-
fluorouracil by gene expression profiling with cDNA microarrays. Int J Oncol. 2005
Aug;27(2):371-6.
55. Ishikawa T, Momiyama N, Hamaguchi Y, Tanabe M, Tomita S, Ichikawa Y,
Nakatani Y, Sasaki T, Nozawa A, Inayama Y, Inui K, Shimada H(6/11). Blue-dye
technique complements four-node sampling for early breast cancer. Eur J Surg Oncol.
2005 Dec;31(10):1119-24. Epub 2005 Jul 7.
56. Ichikawa Y, Ishikawa T, Momiyama N, Kamiyama M, Sakurada H, Matsuyama R,
Hasegawa S, Chishima T, Hamaguchi Y, Fujii S, Saito S, Kubota K, Hasegawa S, Ike
H, Oki S, Shimada H.(1/16) Matrilysin (MMP-7) degrades VE-cadherin and
accelerates accumulation of beta-catenin in the nucleus of human umbilical vein
endothelial cells. Oncol Rep. 2006
57. Morioka D, Watanabe K, Makino H, Saito S, Ueda M, Kubota T, Sekido H, Matsuo
K, Ichikawa Y, Endo I, Togo S, Shimada H. (9/12) Safety limit of the extent of
hepatectomy for rats with moderately fatty liver: experimental study concerning
living liver donor safety. J Gastroenterol Hepatol. 2006 Feb;21(2):367-73.
58. Matsuyama R, Togo S, Shimizu D, Momiyama N, Ishikawa T, Ichikawa Y, Endo I,
Kunisaki C, Suzuki H, Hayasizaki Y, Shimada H. (6/11) Predicting 5-fluorouracil
chemosensitivity of liver metastases from colorectal cancer using primary tumor
specimens: three-gene expression model predicts clinical response. Int J Cancer.
2006 Jul 15;119(2):406-13.
59. Kimura H, Shimada H, Ike H, Yamaguchi S, Ichikawa Y, Kikuchi M, Fujii S, Ohki
S. (5/8) Colonic J-pouch decreases bowel frequency by improving the evacuation ratio.
Hepatogastroenterology. 2006 Nov-Dec;53(72):854-7.
60. Otsuka Y, Ichikawa Y, Kunisaki C, Matsuda G, Akiyama H, Nomura M, Togo S,
Hayashizaki Y, Shimada H. (2/9) Correlating purity by microdissection with gene
expression in gastric cancer tissue. Scand J Clin Lab Invest. 2007;67(4):367-79.
61. Mori R, Ishikawa T, Ichikawa Y, Taniguchi K, Matsuyama R, Ueda M, Fujii Y,
Endo I, Togo S, Danenberg PV, Shimada H. (3/11) Human equilibrative nucleoside
transporter 1 is associated with the chemosensitivity of gemcitabine in human
pancreatic adenocarcinoma and biliary tract carcinoma cells. Oncol Rep. 2007
May;17(5):1201-5.
62. Ishikawa T, Miyajima E, Sasaki T, Tanabe M, Matsumoto C, Nozawa A, Kawachi
K,
Fukuno Y, Takeda H, Hayashi T, Onaka S, Momiyama N, Ichikawa Y, Inui K, Shimada
H. (13/15) Transcription-reverse transcription concerted reaction and minimal residual
disease in axillary sentinel nodes of breast cancer. Eur J Surg Oncol. 2007
May;33(4):430-4. Epub 2006 Nov 13.
63. Kunisaki C, Makino H, Suwa H, Sato T, Oshima T, Nagano Y, Fujii S, Akiyama H,
Nomura M, Otsuka Y, Ono HA, Kosaka T, Takagawa R, Ichikawa Y, Shimada H.
(14/15) Impact of splenectomy in patients with gastric adenocarcinoma of the cardia. J
Gastrointest Surg. 2007 Aug;11(8):1039-44. PubMed PMID: 17514409.
64. Hoshi K, Takakura H, Mitani Y, Tatsumi K, Momiyama N, Ichikawa Y, Togo S,
Miyagi T, Kawai Y, Kogo Y, Kikuchi T, Kato C, Arakawa T, Uno S, Cizdziel PE,
Lezhava A, Ogawa N, Hayashizaki Y, Shimada H. (5/19) Rapid detection of epidermal
growth factor receptor mutations in lung cancer by the SMart-Amplification Process.
Clin Cancer Res. 2007 Sep 1;13(17):4974-83.
65. Watanabe J, Mitani Y, Kawai Y, Kikuchi T, Kogo Y, Oguchi-Katayama A,
Kanamori
H, Usui K, Itoh M, Cizdziel PE, Lezhava A, Tatsumi K, Ichikawa Y, Togo S, Shimada
H, Hayashizaki Y. (13/16) Use of a competitive probe in assay design for genotyping of
the UGT1A1 *28 microsatellite polymorphism by the smart amplification process.
Biotechniques. 2007 Oct;43(4):479-84.
66. Kunisaki C, Makino H, Takagawa R, Oshima T, Nagano Y, Fujii S, Otsuka Y,
Akiyama H, Ono HA, Kosaka T, Ichikawa Y, Shimada H.(11/12) Impact of palliative
gastrectomy in patients with incurable advanced gastric cancer. Anticancer Res.
2008 Mar-Apr;28(2B):1309-15.
☆67. Yamada M, Ichikawa Y, Yamagishi S, Momiyama N, Ota M, Fujii S, Tanaka K,
Togo S, Ohki S, Shimada H. (2/10) Amphiregulin is a promising prognostic marker for
liver metastases of colorectal cancer. Clin Cancer Res. 2008 Apr 15;14(8):2351-6.
68. Kunisaki C, Makino H, Takagawa R, Yamamoto N, Nagano Y, Fujii S, Kosaka T,
Ono HA, Otsuka Y, Akiyama H, Ichikawa Y, Shimada H. (11/12) Surgical outcomes in
esophageal cancer patients with tumor recurrence after curative esophagectomy. J
Gastrointest Surg. 2008 May;12(5):802-10.
69. Taniguchi K, Momiyama N, Ueda M, Matsuyama R, Mori R, Fujii Y, Ichikawa Y,
Endo I, Togo S, Shimada H. (7/10) Targeting of CDC20 via small interfering RNA
causes
enhancement of the cytotoxicity of chemoradiation. Anticancer Res. 2008 May-Jun;28:
1559-63.
70. Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa
Y, Ishikawa T, Sasaki T, Kubota Y, Inayama Y, Aoki I, Ohno S, Shimada H. (7/14) The
overexpression and altered localization of the atypical protein kinase C
lambda/iota in breast cancer correlates with the pathologic type of these tumors.
Hum Pathol. 2008 Jun;39(6):824-31.
71. Kunisaki C, Makino H, Takagawa R, Oshima T, Nagano Y, Kosaka T, Ono HA,
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prognostic factor in patients with gastric cancer. Ann Surg Oncol. 2008 Jul;15(7):1959-
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72. Tatsumi K, Mitani Y, Watanabe J, Takakura H, Hoshi K, Kawai Y, Kikuchi T,
Kogo Y, Oguchi-Katayama A, Tomaru Y, Kanamori H, Baba M, Ishidao T, Usui K,
Itoh
M, Cizdziel PE, Lezhava A, Ueda M, Ichikawa Y, Endo I, Togo S, Shimada H,
Hayashizaki Y. (19/23) Rapid screening assay for KRAS mutations by the modified
smart amplification process. J Mol Diagn. 2008 Nov;10(6):520-6.
73. Takagawa R, Fujii S, Ohta M, Nagano Y, Kunisaki C, Yamagishi S, Osada S,
Ichikawa Y, Shimada H. (8/9) Preoperative serum carcinoembryonic antigen level as a
predictive factor of recurrence after curative resection of colorectal cancer. Ann Surg
Oncol. 2008 Dec;15(12):3433-9.
74. Ueda M, Endo I, Nakashima M, Minami Y, Takeda K, Matsuo K, Nagano Y,
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K, Ichikawa Y, Togo S, Kunisaki C, Shimada H. (9/12) Prognostic factors after
resection
of pancreatic cancer. World J Surg. 2009 Jan;33(1):104-10.
75. Nojiri K, Iwakawa M, Ichikawa Y, Imadome K, Sakai M, Nakawatari M, Ishikawa
K, Ishikawa A, Togo S, Tsujii H, Shimada H, Imai T. (3/12) The proangiogenic factor
ephrin-A1 is up-regulated in radioresistant murine tumor by irradiation. Exp Biol
Med (Maywood). 2009 Jan;234(1):112-22.
76. Shimizu T, Togo S, Kumamoto T, Makino H, Morita T, Tanaka K, Kubota T,
Ichikawa Y, Nagasima Y, Okazaki Y, Hayashizaki Y, Shimada H. (8/12) Gene
expression
during liver regeneration after partial hepatectomy in mice lacking type 1 tumor
necrosis factor receptor. J Surg Res. 2009 Apr;152(2):178-88.
77. Fujii S, Shimada H, Yamagishi S, Ota M, Ichikawa Y, Kunisaki C, Ike H, Ohki
S. (6/8) Surgical strategy for local recurrence after resection of rectal cancer.
Hepatogastroenterology. 2009 May-Jun;56(91-92):667-71.
78. Fujii S, Shimada H, Ike H, Kunisaki C, Ohki S, Ichikawa Y, Ohta M, Yamagishi
S, Osada S. (6/9) Reduction of postoperative abdominal adhesion and ileus by a
bioresorbable membrane. Hepatogastroenterology. 2009 May-Jun;56(91-92):725-8.
79. Ishikawa T, Shimizu S, Katayama K, Chishima T, Hamaguchi Y, Doi T, Tanabe M,
Kasahara A, Yamaguchi N, Narui K, Ohta I, Matsumoto C, Shimizu D, Kito A, Suda T,
Inaba M, Asaga T, Momiyama N, Ichikawa Y, Yoshimoto M, Morita S, Shimada
H.(19/22) Feasibility of AC/EC followed by weekly paclitaxel in node-positive breast
cancer in Japan. Anticancer Res. 2009 May;29(5):1515-20.
80. Takahashi T, Togo S, Kumamoto T, Watanabe K, Kubota T, Ichikawa Y, Endo I,
Kunisaki C, Nagashima Y, Fujimoto J, Shimada H. (6/11) Transfection of NF-kappaB
decoy oligodeoxynucleotides into macrophages reduces murine fatal liver failure after
excessive hepatectomy. J Surg Res. 2009 Jun 15;154(2):179-86.
81. Yoneda K, Iida H, Endo H, Hosono K, Akiyama T, Takahashi H, Inamori M, Abe
Y,
Yoneda M, Fujita K, Kato S, Nozaki Y, Ichikawa Y, Uozaki H, Fukayama M,
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T, Kodama T, Aburatani H, Miyazawa C, Ishii K, Hosomi N, Sagara M, Takahashi M,
Ike H, Saito H, Kusakabe A, Nakajima A. (9/26) Identification of Cystatin SN as a
novel
tumor marker for colorectal cancer. Int J Oncol. 2009 Jul;35(1):33-40.
82. Fujii S, Shimada H, Yamagishi S, Ota M, Kunisaki C, Ike H, Ichikawa Y. (7/7)
Evaluation of intraperitoneal lavage cytology before colorectal cancer resection.
Int J Colorectal Dis. 2009 Aug;24(8):907-14.
83. Ishikawa T, Sasaki T, Miyajima E, Shimizu D, Nozawa A, Kawachi K, Takase A,
Miyazaki N, Tomioka R, Kikuchi M, Amari Y, Fukuno Y, Takeda H, Hayashi T, Onaka
S, Ichikawa Y, Shimada H. (16/17) Pathological examination with two-millimetre serial
sectioning for sentinel lymph node biopsies in breast cancer. Eur J Surg Oncol.
2009 Aug;35(8):895-6.
○84. Ichikawa Y, Goto A, Hirokawa S, Kijima M, Ishikawa T, Chishima T, Suwa H,
Yamamoto H, Yamagishi S, Osada S, Ota M, Fujii S. (1/12) Allergic reactions to
oxaliplatin in a single institute in Japan. Jpn J Clin Oncol. 2009
Sep;39(9):616-20.
85. Shimada H, Tanaka K, Endou I, Ichikawa Y. (4/4) Treatment for colorectal liver
metastases: a review. Langenbecks Arch Surg. 2009 Nov;394(6):973-83.
86. Goshima Y, Usui H, Shiozawa T, Hida T, Kuraoka S, Takeshita S, Yamashita N,
Ichikawa Y, Kamiya Y, Gotoh T, Gotoh T. (8/11) Computational analysis of the effects
of
antineoplastic agents on axonal transport. J Pharmacol Sci. 2010;114(2):168-79.
87. Uchiyama T, Goto A, Sakai E, Sekino Y, Iida H, Endo H, Hosono K, Sakamoto Y,
Koide T, Takahashi H, Yoneda M, Tokoro C, Abe Y, Shimamura T, Kobayashi N,
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K, Maeda S, Nakajima A, Ichikawa Y, Inamori M. (18/19) Endoscopic hemostasis
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88. Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama
Y, Aoki I, Kunisaki C, Endo I, Nagashima Y, Ohno S. (3/12) High expression of
atypical
protein kinase C lambda/iota in gastric cancer as a prognostic factor for
recurrence. Ann Surg Oncol. 2010 Jan;17(1):81-8.
89. Fujii S, Ota M, Yamagishi S, Kunisaki C, Osada S, Suwa H, Ichikawa Y, Shimada
H. (7/8) A Y-shaped vinyl hood that creates pneumoperitoneum in laparoscopic rectal
cancer surgery (Y-hood method.): a new technique for laparoscopic low anterior
resection. Surg Endosc. 2010 Feb;24(2):476-84.
90. Ichikawa Y, Miyagi Y, Fujii S, Ota M, Yamagishi S, Hasegawa S, Saito S, Ike
H, Ohki S, Nakano A, Matsumura N, Ishikawa T, Kunizaki C, Shimada H.(1/12)
Gastrointestinal stromal tumor with two genetic abnormalities on different alleles:
report of a case. Surg Today. 2010 Mar;40(3):262-6.
91. Fujii S, Ota M, Ichikawa Y, Yamagishi S, Osada S, Suwa H, Kunisaki C, Ohki S,
Endo I. (3/9) Paraaortic lymph node metastasis showed CR to UFT/LV therapy in
elderly rectal cancer. Hepatogastroenterology. 2010 May-Jun;57(99-100):472-6.
92. Ishikawa T, Shimizu D, Sasaki T, Morita S, Tanabe M, Ota I, Kawachi K, Nozawa
A, Chishima T, Ichikawa Y, Endo I, Shimada H. (10/12)
A human epidermal growth factor receptor 2 expression-based approach to neoadjuvant
chemotherapy for operable breast cancer. Jpn J Clin Oncol. 2010 Jul;40(7):620-6.
93. Narui K, Ishikawa T, Kito A, Shimizu D, Chishima T, Momiyama N, Ichikawa Y,
Sasaki T, Nozawa A, Inayama Y, Shimada H, Endo I. (6/11) Observational study of
blue
dye-assisted four-node sampling for axillary staging in early breast cancer. Eur J Surg
Oncol. 2010 Aug;36(8):731-6.
94. Fujii S, Ota M, Ichikawa Y, Yamagishi S, Watanabe K, Tatsumi K, Watanabe J,
Suwa H, Oshima T, Kunisaki C, Ohki S, Endo I, Shimada H. (3/13) Comparison of
short, long-term surgical outcomes and mid-term health-related quality of life after
laparoscopic and open resection for colorectal cancer: a case-matched control study. Int
J Colorectal Dis. 2010 Nov;25(11):1311-23.
95. Ota M, Fujii S, Ichikawa Y, Suwa H, Tatsumi K, Watanabe K, Tanaka K, Akiyama
H, Endo I. (3/9) Clinical characteristics of rectal cancer involving the anal canal. J
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96. Fujii S, Watanabe K, Ota M, Yamagishi S, Kunisaki C, Osada S, Ike H, Ichikawa
Y, Endo I, Shimada H. (8/10) Solo surgery in laparoscopic colectomy: a case-matched
study comparing robotic and human scopist. Hepatogastroenterology. 2011
Mar-Apr;58(106):406-10.
97. Nojiri K, Tanaka K, Nagano Y, Ueda M, Matsuo K, Ota M, Ichikawa Y, Shimada
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Endo I. (7/9) Efficacy of surgery for lung metastases from colorectal cancer
synchronous to or following that for liver metastases. Anticancer Res. 2011
Mar;31(3):1049-54.
98. Makino H, Shimada H, Morioka D, Kunisaki C, Morita T, Matsuyama R, Kubota T,
Shimizu D, Ichikawa Y, Tanaka K, Matsuo K, Togo S, Endo I, (9/13) Nagashima Y,
Okazaki Y, Hayashizaki Y. Analysis of gene expression profiles in fatal hepatic failure
after hepatectomy in mice. J Surg Res. 2011 Jul;169(1):36-43.
99. Tanaka K, Ichikawa Y, Endo I. (2/3) Liver resection for advanced or aggressive
colorectal cancer metastases in the era of effective chemotherapy: a review. Int
J Clin Oncol. 2011 Oct;16(5):452-63. doi: 10.1007/s10147-011-0291-6.
100. Ishikawa T, Shimizu D, Yamada A, Sasaki T, Morita S, Tanabe M, Kawachi K,
Nozawa A, Chishima T, Kimura M, Ichikawa Y, Endo I. (11/12) Impacts and predictors
of cytotoxic anticancer agents in different breast cancer subtypes. Oncol Res. 2012;
20(2-3):71-9.
101. Tanabe M, Endo I, Masunari H, Sugita M, Morioka D, Ishikawa T, Ichikawa Y,
Shimada H. (7/8) Is lymph-node micrometastasis in gallbladder cancer a significant
prognostic factor? Hepatogastroenterology. 2012 Jan-Feb;59(113):31-5.
102. Fujii S, Watanabe K, Ota M, Watanabe J, Ichikawa Y, Yamagishi S, Tatsumi K,
Suwa H, Kunisaki C, Taguri M, Morita S, Endo I. (5/12) Laparoscopic colorectal cancer
surgery by a colon lifting-up technique that decreases the number of access ports:
comparison by propensity scoring of short-term and long-term outcomes with standard
multiport laparoscopic surgery. Surg Laparosc Endosc Percutan Tech. 2012 Feb;22(1):
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103. Fujii S, Watanabe K, Ota M, Watanabe J, Ichikawa Y, Yamagishi S, Tatsumi K,
Suwa H, Kunisaki C, Taguri M, Morita S, Endo I.(5/12) Single-incision laparoscopic
surgery using colon-lifting technique for colorectal cancer: a matched case-control
comparison with standard multiport laparoscopic surgery in terms of short-term
results and access instrument cost. Surg Endosc. 2012 May;26(5):1403-11.
104. Tanaka K, Kumamoto T, Nojiri K, Takeda K, Ichikawa Y, Endo I. (5/6) Timing of
two-stage liver resection during chemotherapy for otherwise unresectable colorectal
metastases. World J Surg. 2012 Aug;36(8):1832-41.
105. Yamada Y, Yamaguchi T, Matsumoto H, Ichikawa Y, Goto A, Kato K,
Hamaguchi T,
Shimada Y. (5/8) Phase II study of oral S-1 with irinotecan and bevacizumab (SIRB) as
first-line therapy for patients with metastatic colorectal cancer. Invest New Drugs. 2012
Aug;30(4):1690-6. doi: 10.1007/s10637-011-9743-0.
106. Momiyama M, Kumamoto T, Suetsugu A, Kishimoto H, Chishima T, Tanaka K,
Akiyama H, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. (8/11) Major liver resection
stimulates stromal recruitment and metastasis compared with repeated minor resection.
J Surg Res. 2012 Nov;178(1):280-7.
107. Shimizu D, Ishikawa T, Tanabe M, Sasaki T, Ichikawa Y, Chishima T, Endo
I.(5/7)
Preoperative endocrine therapy with goserelin acetate and tamoxifen in hormone
receptor-positive premenopausal breast cancer patients. Breast Cancer. 2012 Nov
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108. Ishikawa T, Shimizu D, Kito A, Ota I, Sasaki T, Tanabe M, Yamada A, Arioka H,
Shimizu S, Wakasugi J, Mori R, Chishima T, Ichikawa Y, Endo I. (13/14) Breast cancer
manifested by hematologic disorders. J Thorac Dis. 2012 Dec;4(6):650-4.
109. Okano Y, Nezu U, Enokida Y, Lee MT, Kinoshita H, Lezhava A, Hayashizaki Y,
Morita S, Taguri M, Ichikawa Y, Kaneko T, Natsumeda Y, Yokose T, Nakayama H,
Miyagi Y, Ishikawa T. (10/16) SNP (-617C>A) in ARE-like loci of the NRF2 gene: a
new
biomarker for prognosis of lung adenocarcinoma in Japanese non-smoking women.
PLoS One. 2013 Sep 11;8(9):e73794.
110. Tanaka K, Hiroshima Y, Nakagawa K, Kumamoto T, Nojiri K, Takeda K, Ota M,
Ichikawa Y, Endo I. (8/9) Two-stage hepatectomy with effective perioperative
chemotherapy does not induce tumor growth or growth factor expression in liver
metastases from colorectal cancer. Surgery. 2013 Feb;153(2):179-88.
111. Yoshihama Y, Izumisawa Y, Akimoto K, Satoh Y, Mizushima T, Satoh K, Chida
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Takagawa R, Akiyama H, Ichikawa Y, Kunisaki C, Inayama Y, Endo I, Nagashima Y,
Ohno S. (10/15) High expression of KIBRA in low atypical protein kinase C-expressing
gastric cancer correlates with lymphatic invasion and poor prognosis. Cancer Sci.
2013 Feb;104(2):259-65.
112. Yamada A, Ishikawa T, Ota I, Kimura M, Shimizu D, Tanabe M, Chishima T,
Sasaki T, Ichikawa Y, Morita S, Yoshiura K, Takabe K, Endo I. (9/13) High expression
of
ATP-binding cassette transporter ABCC11 in breast tumors is associated with
aggressive subtypes and low disease-free survival. Breast Cancer Res Treat. 2013
Feb;137(3):773-82.
113. Shimada K, Ishikawa T, Nakamura F, Shimizu D, Chishima T, Ichikawa Y, Sasaki
T, Endo I, Nagashima Y, Goshima Y. (6/10) Collapsin response mediator protein 2 is
involved in regulating breast cancer progression. Breast Cancer. 2013 Feb 5.
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114. Hino-Shishikura A, Suzuki A, Minamimoto R, Shizukuishi K, Oka T, Tateishi U,
Sugae S, Ichikawa Y, Horiuchi C, Inoue T. (8/10) Biodistribution and radiation
dosimetry of [¹⁸F]-5-fluorouracil. Appl Radiat Isot. 2013 May;75:11-7.
115. Fujii S, Ishibe A, Ota M, Yamagishi S, Watanabe K, Watanabe J, Kanazawa A,
Ichikawa Y, Oba M, Morita S, Hashiguchi Y, Kunisaki C, Endo I. (8/13) Short-term
results of a randomized study between laparoscopic and open surgery in elderly
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116. Shimada K, Ishikawa T, Yoneyama S, Kita K, Narui K, Sugae S, Shimizu D,
Tanabe M, Sasaki T, Chishima T, Ichikawa Y, Endo I. (11/12) Early-onset brain
metastases in a breast cancer patient after pathological complete response to
neoadjuvant chemotherapy. Anticancer Res. 2013 Nov;33(11):5119-21.
117. Kumamoto T, Tanaka K, Matsuo K, Takeda K, Nojiri K, Mori R, Taniguchi K,
Matsuyama R, Ueda M, Akiyama H, Ichikawa Y, Ota M, Endo I. (11/13) Adjuvant
hepatic arterial infusion chemotherapy with 5-Fluorouracil and interferon after curative
resection of hepatocellular carcinoma: a preliminary report. Anticancer Res. 2013
Dec;33(12):5585-90.
118. Hiroshima Y, Nakamura F, Miyamoto H, Mori R, Taniguchi K, Matsuyama R,
AkiyamaH, Tanaka K, Ichikawa Y, Kato S, Kobayashi N, Kubota K, Nagashima Y,
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associated with liver metastasis and poor survival in pancreatic cancer. Ann Surg Oncol.
2013 Dec;20 Suppl 3:S369-78.
119. Watanabe J, Tatsumi K, Ota M, Suwa Y, Suzuki S, Watanabe A, Ishibe A,
Watanabe K, Akiyama H, Ichikawa Y, Morita S, Endo I. (10/12) The impact of visceral
obesity on surgical outcomes of laparoscopic surgery for colon cancer. Int J Colorectal
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120. Ichikawa Y, Goto A, Kobayashi N, Ota M, Tokuhisa M, Ishibe A, Watanabe J,
Watanabe K, Ishikawa T, Tanaka K, Akiyama H, Fujii S and Endo I. (1/13) Does
Resection of Primary Lesions Show Survival Benefit for Stage IV Colorectal Cancer
Patients with Unresectable Metastases? Hepato-Gastroenterology 2013; 60:00-00 doi
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121. Kumamoto T, Tanaka K, Takeda K, Nojiri K, Mori R, Taniguchi K, Matsuyama R,
Ueda M, Sugita M, Ichikawa Y, Nagashima Y, Endo I. (10/12) Intrahepatic
cholangiocarcinoma arising 28 years after excision of a type IV-A congenital
choledochal cyst: report of a case. Surg Today. 2014 Feb;44(2):354-8.
122. Homma Y, Taniguchi K, Murakami T, Nakagawa K, Nakazawa M, Matsuyama R,
Mori R, Takeda K, Ueda M, Ichikawa Y, Tanaka K, Endo I. (10/12) Immunological
impact of neoadjuvant chemoradiotherapy in patients with borderline resectable
pancreatic ductal adenocarcinoma. Ann Surg Oncol. 2014 Feb;21(2):670-6.
123. Yamamoto S, Tanaka K, Takeda K, Akiyama H, Ichikawa Y, Nagashima Y, Endo
I.(5/7) Patients with CD133-Negative Colorectal Liver Metastasis Have a Poor
Prognosis After Hepatectomy. Ann Surg Oncol. 2014 Feb 20.
124. Homma Y, Taniguchi K, Nakazawa M, Matsuyama R, Mori R, Takeda K,
Ichikawa Y, Tanaka K, Endo I. (7/9) Changes in the immune cell population and cell
proliferation in peripheral blood after gemcitabine-based chemotherapy for pancreatic
cancer. Clin Transl Oncol. 2014 Mar;16(3):330-5.
125. Prediction of Lateral Pelvic Lymph-Node Metastasis in Low Rectal Cancer by
Magnetic Resonance Imaging.(8/10) Ishibe A, Ota M, Watanabe J, Suwa Y, Suzuki S,
Kanazawa A, Watanabe K, Ichikawa Y, Kunisaki C, Endo I. World J Surg. 2016
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126. High infiltration of mast cells positive to tryptase predicts worse outcome
following resection of colorectal liver metastases.(2/11) Suzuki S, Ichikawa Y,
Nakagawa K, Kumamoto T, Mori R, Matsuyama R, Takeda K, Ota M, Tanaka K,
Tamura T, Endo I. BMC Cancer. 2015 Nov 4;15:840
127. Incidence and risk factors for rectovaginal fistula after low anterior resection for
rectal cancer. (13/15) Watanabe J, Ota M, Kawaguchi D, Shima H, Kaida S, Osada S,
Kamimukai N, Kamiya N, Ishibe A, Watanabe K, Matsuyama R, Akiyama H, Ichikawa
Y, Oba M, Endo I. Int J Colorectal Dis. 2015 Dec;30(12):1659-66
128. Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant
Patient Soft-Tissue Sarcoma in Nude Mice. (17/20) Hiroshima Y, Zhao M, Zhang Y,
Zhang N, Maawy A, Murakami T, Mii S, Uehara F, Yamamoto M, Miwa S, Yano S,
Momiyama M, Mori R, Matsuyama R, Chishima T, Tanaka K, Ichikawa Y, Bouvet M,
Endo I, Hoffman RM. PLoS One. 2015 Aug 3;10(8):e0134324
129. S-1 and irinotecan with or without bevacizumab versus 5-fluorouracil and
leucovorin plus oxaliplatin with or without bevacizumab in metastatic colorectal cancer:
a pooled analysis of four phase II studies. (5/11) Iwasa S, Nagashima K, Yamaguchi T,
Matsumoto H, Ichikawa Y, Goto A, Yasui H, Kato K, Okita NT, Shimada Y, Yamada
Y. Cancer Chemother Pharmacol. 2015 Sep;76(3):605-14
130. Exosomal miRNAs from Peritoneum Lavage Fluid as Potential Prognostic
Biomarkers of Peritoneal Metastasis in Gastric Cancer. (2/11) Tokuhisa M, Ichikawa Y,
Kosaka N, Ochiya T, Yashiro M, Hirakawa K, Kosaka T, Makino H, Akiyama H,
Kunisaki C, Endo I. PLoS One. 2015 Jul 24;10(7):e0130472
131. Tumor-Targeting Salmonella typhimurium A1-R in Combination with
Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived
Mouse Models. (17/20) Hiroshima Y, Zhang Y, Zhao M, Zhang N, Murakami T,
Maawy A, Mii S, Uehara F, Yamamoto M, Miwa S, Yano S, Momiyama M, Mori R,
Matsuyama R, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM.
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132. Nutritional management of anastomotic leakage after colorectal cancer surgery
using elemental diet jelly. (10/12) Ishibe A, Ota M, Kanazawa A, Watanabe J, Tatsumi
K, Watanabe K, Godai T, Yamagishi S, Fujii S, Ichikawa Y, Kunisaki C, Endo I.
Hepatogastroenterology. 2015 Jan-Feb;62(137):30-3.
133. Randomised phase II trial of S-1 plus oxaliplatin vs S-1 in patients with
gemcitabine-refractory pancreatic cancer. (20/28) Ohkawa S, Okusaka T, Isayama H,
Fukutomi A, Yamaguchi K, Ikeda M, Funakoshi A, Nagase M, Hamamoto Y,
Nakamori S, Tsuchiya Y, Baba H, Ishii H, Omuro Y, Sho M, Matsumoto S, Yamada N,
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134. Fluorescence-guided surgery, but not bright-light surgery, prevents local
recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) model
resistant to neoadjuvant chemotherapy (NAC). (10/13) Hiroshima Y, Maawy A, Zhang
Y, Murakami T, Momiyama M, Mori R, Matsuyama R, Chishima T, Tanaka K,
Ichikawa Y, Endo I, Hoffman RM, Bouvet M. Pancreatology. 2015 May-Jun;15(3):295-
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135. Associating liver partition and portal vein ligation for staged hepatectomy
(ALPPS): short-term outcome, functional changes in the future liver remnant, and tumor
growth activity. (7/10) Tanaka K, Matsuo K, Murakami T, Kawaguchi D, Hiroshima Y,
Koda K, Endo I, Ichikawa Y, Taguri M, Tanabe M. Eur J Surg Oncol. 2015
Apr;41(4):506-12. doi: 10.1016/j.ejso.2015.01.031. Epub 2015
136. Establishment of a patient-derived orthotopic Xenograft (PDOX) model of HER-2-
positive cervical cancer expressing the clinical metastatic pattern. (14/18) Hiroshima Y,
Zhang Y, Zhang N, Maawy A, Mii S, Yamamoto M, Uehara F, Miwa S, Yano S,
Murakami T, Momiyama M, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Murata T,
Endo I, Hoffman RM. PLoS One. 2015 Feb 17;10(2):e0117417. doi:
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137. Neoadjuvant docetaxel/cyclophosphamide in triple-negative breast cancer:
predictive value of class III-β tubulin and non-basal subtype. (10/11) Shimada K,
Ishikawa T, Kita K, Narui K, Sugae S, Shimizu D, Tanabe M, Sasaki T, Chishima T,
Ichikawa Y, Endo I. Anticancer Res. 2015 Feb;35(2):907-12.
138. Patient-derived orthotopic xenograft (PDOX) nude mouse model of soft-tissue
sarcoma more closely mimics the patient behavior in contrast to the subcutaneous
ectopic model. (16/19) Hiroshima Y, Zhang Y, Zhang N, Uehara F, Maawy A,
Murakami T, Mii S, Yamamoto M, Miwa S, Yano S, Momiyama M, Mori R,
Matsuyama R, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM.
Anticancer Res. 2015 Feb;35(2):697-701.
139. A systematic review of laparoscopic total gastrectomy for gastric cancer. (6/9)
Kunisaki C, Makino H, Takagawa R, Kimura J, Ota M, Ichikawa Y, Kosaka T,
Akiyama H, Endo I. Gastric Cancer. 2015 Apr;18(2):218-26. doi: 10.1007/s10120-015-
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140. A prospective feasibility study of sentinel node biopsy by modified Indigocarmine
blue dye methods after neoadjuvant chemotherapy for breast cancer. (7/8) Kida K,
Ishikawa T, Yamada A, Shimizu D, Tanabe M, Sasaki T, Ichikawa Y, Endo I.
Eur J Surg Oncol. 2015 Apr;41(4):566-70. doi: 10.1016/j.ejso.2014.10.066. Epub 2015
141. Endoscopic inside stent placement is suitable as a bridging treatment for
preoperative biliary tract cancer. (15/15) Kobayashi N, Watanabe S, Hosono K, Kubota
K, Nakajima A, Kaneko T, Sugimori K, Tokuhisa M, Goto A, Mori R, Taniguchi K,
Matsuyama R, Endo I, Maeda S, Ichikawa Y. BMC Gastroenterol. 2015 Feb 5;15:8.
142. Preliminary results of 'liver-first' reverse management for advanced and aggressive
synchronous colorectal liver metastases: a propensity-matched analysis. (6/8) Tanaka K,
Murakami T, Matsuo K, Hiroshima Y, Endo I, Ichikawa Y, Taguri M, Koda K. Dig
Surg. 2015;32(1):16-22. doi: 10.1159/000370253. Epub 2015 Jan 22
143. Evaluation of the intestinal blood flow near the rectosigmoid junction using the
indocyanine green fluorescence method in a colorectal cancer surgery. (11/12)
Watanabe J, Ota M, Suwa Y, Suzuki S, Suwa H, Momiyama M, Ishibe A, Watanabe K,
Masui H, Nagahori K, Ichikawa Y, Endo I. Int J Colorectal Dis. 2015 Mar;30(3):329-
35. doi: 10.1007/s00384-015-2129-6.
144. Thrombomodulin improves rat survival after extensive hepatectomy. (13/14) Ota
Y, Kumamoto T, Ishibe A, Watanabe K, Mori R, Taniguchi K, Matsuyama R, Makino
H, Ueda M, Kubota T, Akiyama H, Tanaka K, Ichikawa Y, Endo I. J Surg Res. 2015
Apr;194(2):375-82.
145. Outcomes of immediate perforator flap reconstruction after skin-sparing
mastectomy following neoadjuvant chemotherapy. (10/13) Narui K, Ishikawa T, Satake
T, Adachi S, Yamada A, Shimada K, Shimizu D, Kida K, Sugae S, Ichikawa Y, Tanabe
M, Sasaki T, Endo I. Eur J Surg Oncol. 2015 Jan;41(1):94-9
146. Optimizing the selection of patients with low rectal cancer for intersphincteric
resection by evaluating vertical invasion to the levator and external sphincter. (2/10)
Narui K, Ichikawa Y, Ike H, Ota M, Saito S, Fujii S, Sasaki T, Nozawa A, Shimada H,
Endo I. Colorectal Dis. 2015 Feb;17(2):133-40.
02Mar2016
Department of Oncology
Yokohama City University, Graduate School of Medicine
Fukuura 3-9 Kanazawa-ku, Yokohama 2360044, Japan
Yasushi Ichikawa M.D., Ph.D.