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CURRICULUM VITAE - HELEN LIAPIS, M.D. Date: August 2015 Citizenship: USA, EU Address and Telephone Numbers: Office: 10810 Executive Center Dr. Ste. 100 | Little Rock, AR 72211

T 501.604.2695 | F 501.604.2699 Present Position: Pathologist at Arkana Laboratories Retired Professor of Pathology and Immunology Washington

University School of Medicine, St. Louis, MO Past Professor of Internal Medicine (Nephrology) Section Head Renal Pathology

Co-director of Clinical Electron Microscopy Laboratory Co-director WU Kidney Translational Research Core, O’Brian Kidney Center

Other current positions Associate Editor Clinical Kidney journal and BMC Nephrology MIDWEST Organ Procurement Task Force Clinical Representative to the Executive Committee of the Faculty Council (ECFC) at WU 2009-13 Interim Medical School Board University of Cyprus

GUREGN Consortium for the MID-NORTHWEST USA Immediate past President Renal Pathology Society

Education: Graduate: 1968-1974 M.D., University of Athens, Medical

School, Athens, Greece Postgraduate: June 1975 Resident in Anatomic Pathology, Red Cross

Hospital, Athens, Greece Nov. 1977- Resident in Surgery, General Hospital Dec. 1978 (Queen Olga), Rhodes, Greece (Obligatory

rural community service) Jan. 1979- Resident in Clinical Pathology, Venereal Dec 1981 Diseases Hospital and Children's Hospital,

Athens, Greece June-Aug 1980 University College London, Dep. of Clinical

Pathology visiting physician

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1982-1985 Resident, combined Anatomic and Clinical

Pathology Program, Department of Pathology, St. Louis University, St. Louis, MO.

1988-1989 Fellow in Pediatric and Renal Pathology St.

Louis University, Cardinal Glennon Children's Hospital, St. Louis, MO.

Academic Positions/Employment: 1986-1987 General Hospital for Respiratory Diseases,

Blood Bank/ Immunopathology consultant, "Hygia Hospital" Athens, Greece

1989-1990 SmithKline Beacham 1991-1994 Instructor- Surgical Pathology

1991-1996 Medical Director of Transfusion Service Department of Pathology at Washington University Medical Center

1991-present Surgical pathologist at Barnes-Jewish-Children’s Hospitals

1991-present Staff pathologist Autopsy service 1994- 2001 Assistant Professor, Department of

Pathology at Washington University 2001-2008 Associate Professor Department of

Pathology and Immunology 2003-2008 Associate Professor Department of Medicine 2008 Professor of Pathology & Immunology 2008 Section Head Renal Pathology 2009 Director Electron Microscopy 2010 Professor Internal Medicine, Renal Division

University/Hospital Appointments and Committees: 1991-June 1994 Chairman, Jewish Hospital Transfusion

Committee

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1991-1994 Jewish Hospital Institutional Review Board (IRB)

1991-1994 Jewish Hospital Quality Assurance

Committee

1994-present Washington University Medical Student Mentor Program for Women

1995-present Research Awareness for Students of

Washington University School of Medicine and St. Louis area high school students

1996-present Washington University Cancer Center 2007-present Careers advisor in Pathology, WU 2007-current Committee for the Distinguished Clinician Award Program, WU 2010-2013 Career Counseling 4th year medical students 2011-current USCAP Ambassadors: mentoring pathology trainees to become future leaders in pathology 2011-2012 Peer Group Mentoring at WU pathology sponsored by the Dean’s office Other professional positions and visiting appointments 2009-current Interim Board Cyprus University Medical School 2010 President Elect Renal Pathology Society 2010 Nemitsas’ Foundation Advisory Board 2010-11 Consultant Adrelyx 2011- current Consultant BIOGEN 2011 American Association for the Advancement of Science grant reviewer 2011-13 USCAP Ambassador (advisor/mentor for pathologists in training) 2011 Science tour in Germany invited by the German Foreign Affairs Education office

2012- current External faculty promotion committee, the Univ of Patras and Univ of Ioannina, Greece

2013-16 ASN Post Graduate education (PGE) cmt 2014 President Renal Pathology Society 2014 CUREGN Consortium: Renal Pathologist

for MIDWEST and NORTHWEST USA

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Board Certification: Certifications: American Board of Pathology 1990 Anatomic and Clinical Pathology Board Eligible Pediatric Pathology 2014 Recertified ABP APCP 1982 Greek Board of Clinical Pathology 1986 Greek Board of Anatomic Pathology Professional Society Memberships: United States and Canadian Academy of Pathology American Society for Investigative Pathology European Society of Pathology The Society for Pediatric Pathology Renal Pathology Society (RPS) International Society of Nephrology (ISN) American Society of Nephrology (ASN) National Kidney Foundation (NKF) International Society for Organ Transplantation American Heart Association International Pediatric Nephrology Association (IPNA)

Undergraduate chapter of the American Medical Women’s Association (AMWA) European Society of Nephrology & Transplantation ERA-EDTA American society of Pediatric Nephrology

Honors and Awards: Missouri Kidney Program, 1994 $10,000

Explant fibroblast culture of obstructed fetal opossum kidneys

Monsanto 2000 $2,000 Study of in vivo expression of Adhesion molecules Fujisawa 2001 $5,000 Viruses and renal allograft pathology

Midwest Stone Institute 1/1-12/30/2002 $ 135,000 PI George Steinhardt, Helen Liapis co-investigator Experimental ureteral obstruction in the opossum

Midwest Stone Institute 1/1-12/30/2003 $10,000 PI Helen Liapis GeneChip arrays in human congenitally obstructed kidneys

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NIH-NIDDK 2003-2007 PI Jeffrey Miner, RO1-DK0646871 Helen Liapis co-investigator, 1 % effort Mechanisms of cell matrix interactions in the kidney Midwest Stone Institute 1/1-12/30 2004 $10,000

PI Helen Liapis Aberrant gene transcript profiles suggest novel therapies for congenital obstructive nephropathy in humans WU pathology internal grants

Gene transcript and protein expression profiles of laser capture micro-dissected (LCM) kidney structures from congenitally obstructed kidneys 2004 $12,965

Gene expression profiles in renal biopsies 2005 $14,000 Gene expression in Diabetic Podocytes 2006 $15,000 R01 DK081592-01A1 (Feng Chen, Renal) 4/6/09-3/31/10 Genetic Determinants in Kidney and Urinary Tract Defects

3.5% effort

NIH, NIDDK 3-1-2005-4-28-13 PI Chen Feng RO1- DK067386 Helen Liapis co-investigator 5% effort

Calcineurin in Congenital Urinary Tract P30 Center for Kidney disease research NIDDK079333 2007-12 5% effort

Translational Research Core [C], animal model Core [D] Clinical trials Renal allograft pathology in the Serolimus protocol: Funded by Wyeth, PI Daniel Brennan April 2006 H. Liapis co-investigator $ 5,000 Management of BK virus in renal allograft recipients: NIH funded study, PI Daniel Brennan H Liapis: collaborator International lupus clinical trial (ATLAS): virtual pathology review: 2011-current Liapis & Gaut

National / International Honors 2014 Cure Glomerulonephropathy Network [CUREGN] Mid and

Northwest USA Consortium 2012 Distinguished Clinician Award, Washington University

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School of Medicine, February 9, 2012 2011 Jacob Churg Award for outstanding contributions in Renal 2011 American Association for the Advancement of Science New York, research Competitiveness Program, grant reviewer Pathology February 26, 2011 2006 Hellenic Spirit Foundation Distinguished Scientist Award, March 18, 2006 2005 National Kidney Foundation, University of Michigan Ann

Arbor, external grant reviewer 2003 Best poster award (Endothelin receptor expression in the

developing kidney of obstructed young opossum) World Congress of Nephrology, Berlin June 8-12, 2003

2003 Ad hoc reviewer National Institute of Health (NIH) Study Section on Urologic Research, March 17-18, 2003

2003 Young investigator award for our work on the genomics of congenital obstructive nephropathy: Renal Pathology Society, 92nd USCAP annual meeting, Washington DC

2002 NIH/NIDDK State of the Art Workshop: strategic planning on congenital obstructive uropathy. March 11-12, 2002

2001-2002 Italian Cancer Society, external reviewer for cancer grant proposals

1995-1999 Missouri Kidney Program, Technical Review Committee Editorial Board Associate Editor Clinical Kidney Journal 2015

British Medical Council (BMC) Nephrology 2012-2015 Editorial Board Pathology Research International 2009-current International Journal of Urology & Nephrology 2003-2011 Hippokratia 2006-current Nephron / Experimental Nephrology 2002-2007 Seminars in Diagnostic Pathology: Guest Editor 2002 Journal Reviewer Nephron /Experimental Nephrology International Journal of Urology & Nephrology Pathology Research International (ad hoc)Kidney International J Am Soc. Nephrology (JASN) Am J Kidney Diseases Nephrology Dialysis Transplantation Clinical Journal American Society of Nephrology CJASN) Transplantation Am J Pathology

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Am J Transplantation Pediatric Nephrology Modern Pathology Histology & Histopathology Archives of Pathology and Lab Medicine Pediatric Pathology Genomics J Clinical Pathology Am J Clinical Pathology British Journal of Cancer British Journal of Pharmacology Pathology, Research & Practice Am J of Nephrology Bibliography:

Peer reviewed manuscripts 1. Liapis AI, Lipscomb GC, Crosser OK, Liapis-Tsiroyianni H: A model of oxygen diffusion in absorbing tissues. Mathematical Modeling 3:83-92, 1980 2. Liapis, H: Monoclonal antibodies in leukemias. Medical Periscope (5) 20-21, 1986 3. deMello DE, Lima H, Liapis H: Midline cervical cysts in children; thyroglossal

anomalies. Arch. Otolaryngol. Head Neck Surg. 113:418-420, 1987 4. Liapis H, Xanthou M, Mandyla H: Immunocytochemical markers for human milk

macrophages and epithelial cells. Recent Advances in Mucosal Immunity, Part A, 431-435, 1987

5. Liapis H: Virological examinations in the hospital laboratory. Applied Clinical Microbiology and Lab. Diagnosis 2:18-22, 1987

6. Liapis H: Interpretation of the HTLV III antibody screening tests. Applied Clinical Microbiology and Lab. Diagnosis 2:51-56, 1987

7. Liapis H: Resolving ABO discrepancies. Applied Clinical Microbiology and Lab Diagnosis 3:42-49, 1988

8. deMello DE, Liapis H, Jureidini S, Nouri S, Kephart G, Gleich GT: Cardiac localization of eosinophil granule major basic protein in acute necrotizing myocarditis. New Engl. J. Med. 323:1542-1545, 1990

9. Liapis H, Crouch EC, Grosso L, Kitazawa S, Wick M: Expression of parathyroid-like protein ( PLP) in normal, proliferative, and neoplastic human breast tissues. Am. J. Pathol 143:1169-1178, 1993

10. Liapis H, Crouch EC, Roby J, Rader J: In situ localization of parathyroid hormone like protein (PLP) and mRNA in intraepithelial neoplasia and invasive carcinomas of the uterine cervix. (cover illustration: corresponding author) Human Pathol 24:1058-1066, 1993

11. Liapis H, Nag M, Steinhardt G: Effects of experimental ureteral obstruction on PDGF-A chain and type I collagen expression in fetal metanephric kidneys. Ped Nephrology 8:548-554, 1994

12. Steinhardt GF, Liapis H, Phillips B, Vogler G, Nag M, Yoon K: Insulin-like growth factor improves renal architecture in fetal kidneys with complete ureteral obstruction. J.

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Urol. 154:690-693, 1995 13. Liapis H, Roby J, Birkland TP, Davila RM, Ritter D, Parks WC: In situ hybridization of

human erythropoietin ( EPO) in pre and post natal kidneys. Ped Pathol & Lab Med 15:875-883, 1995

14. Larson RS, Rudloff MA, Liapis H, Manes JL, Davila R, Kissane J: The Ivemark syndrome: prenatal diagnosis of an uncommon cystic renal lesion with heterogeneous associations. Ped Nephrol 9:594-598, 1995

15. Carlini RG, Gupta A, Liapis H, Rothstein M: Endothelin-1 release by erythropoietin involves calcium signaling in endothelial cells. J. Cardiovasc Pharm 26:889-892, 1995

16. Liapis H, Flath A, Kitazawa S: Integrin α"vß3 expression by bone-residing breast cancer metastases. Diagn Mol Pathol 5(2):127-135, 1996

17. Marley EF, Liapis H, Hess JL, Dehner LP: Myocardial extramedullary hematopoiesis following myocardial infarction. Cardiovasc Pathol 5(6):333-336, 1996

18. Matayoshi A, Brown C, DiPersio J, Hang J, Liapis H, Kuestner R, Pacificci R: Blood-mobilized hematopoietic precursors differentiate into osteoclasts in absence of stromal cells. Proc Nat Acad Sci U.S.A. 93:10785-10790, 1996

19. Liapis H, Adler L, Wick MR, Rader SJ: Expression of avb3 integrin in ovarian epithelial tumors of low malignant potential is less frequent in contrast to ovarian carcinomas. Hum Pathol 28:443-449, 1997

20. Marley EF, Liapis H, Humphrey PA, Nadler R, Siegal C, Zhu X, Brandt JM, Dehner LP: Primitive neuroectodermal tumor of kidney: Another enigma. A pathologic, immunohistochemical and molecular diagnostic study. Am. J. Surg. Pathol. 21(3):354-359, 1997

21. Liapis H, Hong Y, Flath A, Steinhardt GF: Increased expression of platelet-derived growth factor A (PDGF-A) and collagenous matrix proteins in congenital multicystic renal dysplasia. Nephron 76:161-170, 1997

22. Basil JB, Kost ER, Liapis, H, Mutch DG: Recurrent ovarian low malignant potential tumor with cardiac metastasis. Obstet. Gynecol. 89 (5 Pt 2):854-856, 1997

23. Liapis H, Hutton K: Detection of integrins in formalin fixed, paraffin embedded tissues. J. Histoch and Cytoch 45 (5)737-741, 1997

24. Liapis H, Vogler G, Steinhardt GF: The North American opossum didelphis virginiana as a fetal nephrotoxicity model; histologic and ultrastructural assessment of uranyl nitrate (UN) induced damage. Microscopy Research and Technique 39, 285-296, 1997

25. Basile DP, Liapis H, Hammerman MR: Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury. Am J Physiol 272(5 Pt 2):F640-647, 1997

26. Hughes J H, El-Mofty S, Sessions D, Liapis H.: Primary intraepithelial paraganglioma with metachronous carotid body tumor: Report of a case and review of the literature. Pathology Research and Practice, 193:791-796, 1997

27. Bershoff- Matcha S J, Roper CC, Liapis H, Cooper J, and Little, JR: Primary pulmonary botryomycosis mimicking actinomycosis. Clin Infectious Dis 26:620-624,1998

28. Rader SJ, Gerhard DS, O’Sullivan M J, Li Y, Li L, Liapis H, Huettner PC.: CIN III

shows frequent allelic loss in 3- and 6p. Genes, Chromosomes and Cancer 22:57-65, 1998

29. Pelletier GJ, Brody SL, Liapis H, White RA, Hackett BP.: A human forkhead / winged helix transcription factor expressed in developing epithelium. Am J Physiology, 274 (18)

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L351-359, 1998 30. Tiniakos D, Yu H, Liapis H.: Osteopontin expression in ovarian carcinomas and tumors

of low malignant potential. Hum Pathol 29:1250-1254, 1998 31. Liapis H. Nag M, Kaji DM.: K-Cl cotransporter in the human kidney. Am J Physiol 275

(Cell Physiol.44):C1432-1437, 1998 32. Liapis H, Marley E F, Lin Y, Dehner LP.: p53 and Ki-67 proliferating cell nuclear

antigen in benign and malignant peripheral nerve sheath tumors in children. Ped and Dev Pathol 2,377-384, 1999

33. Liapis H, Miner JH.: The potential of gene therapy. Paradigms from animal models for kidney disease. Iatriki 75(1):30-36, 1999

34. Nakopoulou L, Liapis H. et al.: Matrix metalloproteinase-1 and 3 in breast cancer: correlation with progesterone receptors and other clinicopathologic features. Human Path 30 (4):436-442, 1999

35. Strauss BL, Guttman DH, Dehner LP, Hirby AH, Liapis H: Molecular analysis of Triton tumors. Human Path 30 (8) 984-988, 1999

36. Fracasso PM, Tan BR, Liapis H: Membranoproliferative glomerulonephritis following gemcitabine and vinorelbine chemotherapy for peritoneal mesothelioma. J Natl Cancer Inst. 91(20):1779-80, 1999

37. Liapis H, Papadakis I, Nakopoulou L. Nodular glomerulosclerosis secondary to mu heavy chain deposits. (cover illustration: corresponding author)Human Path 31:122-125, 2000

38. Liapis H, Yu H, Steinhardt GF: Cell proliferation, apoptosis, Bcl-2 and Bax expression in obstructed opossum early metanephroi. J Urol, 164:(2) 511-517, 2000

39. Hruska KA, Guanglie G, Liapis H, Klahr S, Morrissey J: Osteogenic protein 1 (OP-1) prevents renal fibrogenesis associated with ureteral obstruction. Am J Physiol / Renal 279:(1) F130-F143, 2000

40. Kulkarni S, Rader js, Zhang F, Liapis H et al: Cyclooxygenase-2 is over-expressed in human cervical cancer. Clin Cancer Res 7(2):429-34, 2001

41. Levy NT, Eisenberg PR, Botney MD, Liapis H, Trulock EP: Resolution of Primary pulmonary hypertension in left native lung, following right single lung transplantation. J Heart and Lung Transplant 20(3):381-4, 2001

42. Rajaram V, Liapis H. Immunoglobulin A nephropathy. Nephrol Dial Transplant. 16 Suppl 6:77-9, 2001

43. Rogers A, Liapis H, Hammerman MR: Transplantation of metanephroi across the major histocompatibility complex in the rat Am J Physiol Regulatory Integrative Comp Physiol 280:R132-R136, 2001

44. Bhayani SB, Liapis H, Kibel AS: Adult clear cell sarcoma of the kidney with atrial thrombus. J Urol 165 (3); 896-897, 2001

45. Guo G, Morrissey J, McCracken,Tolley T, Liapis H, Klahr S. Contributions of angiotensin II and tumor necrosis factor-a to the development of renal fibrosis. Am J Physiol 280 (5):F777-85, 2001

46. Liapis H, Barent B, Steinhardt GF: Extracellular matrix in fetal kidney following experimental obstruction. J Urol 166; 1433-1438, 2001

47. Nakopoulou L, Gakiopoulou, Liapis H et al: MMP-3 and MMP-1 in bladder cancer: a comparison with clinicopathologic features and survival. Appl Immunohistochm Molecul Morphol 9 (2):130-7, 2001

48. Liapis H, Godken N, Hmiel P, Miner JH. Histopathology, ultrastructure and clinical

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phenotypes in thin glomerular basement membrane disease variants. Human Path 33(8):836-45, 2002

49. Arie Perry, M.D., Sarah N. Kunz, Christine E. Fuller, M.D., Ruma Banerjee, Edith F. Marley, M.D., Helen Liapis, M.D., Mark A. Watson, M.D., Ph.D., David H. Gutmann, M.D., Ph.D. Differential NF1, p16, and EGFR Patterns by Interphase Cytogenetics (FISH) in Malignant Peripheral Nerve Sheath Tumor (MPNST) and Morphologically Similar Spindle Cell Neoplasms. J. Neuropathology Experimental Neurology, 61(8):702-709, 2002

50. Agfa I, Mahoney R, Beardsley M, Liapis H, Cowart R, Juknevicius I. Systemic amyloidosis associated with pleomorphic sarcoma of the spleen and remission of the nephrotic syndrome after removal of the tumor. Am J Kidney Dis 40 (2): 411-415, 2002

51. Cozzolino M, Dusso A, Liapis H, Finch J, Burke S, Slatopolsky E. Advantage of sevelamer hydrochloride (RenalGel) over calcium carbonate on ectopic calcification in

uremic rats. J Am Soc Nephrol 13(9):2299-308, 2002 52. Akimoto T, Liapis H, Hammerman MR. Microvessel formation from mouse embryonic

aortic explants, is hypoxia and VEGF dependent. Am J Phys, Regulatory 283:R487- R495, 2002

53. Liapis H, Doshi RH, Watson MA, Liapis A, Steinhardt GF. Reduced renin expression and altered gene transcript profiles in multicystic dysplastic kidneys. J Urol 168(4 Pt 2):1816-20, 2002

54. Foster K, Salinas L, Miller B, Liapis H.: Unusual types of diabetic GN and dual disease. Sem in Diag Path 19(3)160-174, 2002 55. Hoch B, Juknevicius I, Liapis H.: Glomerular pathology in Hepatitis C; correlation with

tissue HPC-PCR. Sem in Diag Path 19 (3) 175-187, 2002 56. Sotsiou F, Dimitriadis G, Liapis H: Diagnostic dilemmas in atypical postinfectious

glomerulonephritis. Sem in Diag Path 19(3) 146-159, 2002 57. Liapis H, Storch GA, Hill DA, Rueda J, Brennan C. Invasive CMV infection of the renal

allograft is much more common than the pathology indicates: A retrospective analysis of quantitative and qualitative buffy coat CMV-PCR, renal biopsy pathology and tissue CMV-PCR. Nephrol Dial Transpl 18(2):397-402, 2003

58. Liapis H. Biology of congenital obstructive nephropathy. Nephron / Exper Nephrol 93(3):E87, 2003 59. Schnitzler MA, Lowell JA, Hmiel SP, Hardinger KL, Liapis H, Ceriotti CS, Brennan DC.

Cytomegalovirus Disease after Prophylaxis with Oral Ganciclovir in Renal Transplantation: The Importance of HLA-DR Matching. J Am Soc Nephrol 14(3):780-5, 2003

60. Wang S, Chen Q, Simon TC, Strebeck F, Chaudhary L, Idleburg C, Morrissey J, Klahr S, Liapis H, Hruska KA: Bone morphogenic protein-7(BMP-7), a novel therapy for diabetic nephropathy. Kidney Int. 63(6):2037-49, 2003

61. Rogers SA, Liapis H, Hammerman MR. Intraperitoneal transplantation of pancreatic anlagen. Am Soc of Artificial Internal Organs (ASAIO) Journal 49, 527-32, 2003

62. Cozzolino M, Dusso A, Liapis H, Finch J, Staniforth M, Burke S, Slatopolski E. Sevelamer hydrochloride prevents high phosphorus-induced vascular calcifications in long-term experimental uremia. Kidney Int 64(5):1653-1661, 2003

63. Thrombotic Microangiopathy involving the kidney: A Histopathologic Perspective.

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Hippokratia 7(4): 152-158, 2003 64. Kameswaran S, Simon TC, Liapis H, Parks WC, McGuire JK. Matrilysin (MMP-7)

expression in renal tubular damage: Association with Wnt4. Kidney Int 65(6):2212-22, 2004

65. Ogunleye DA, Lewin SN, Liapis H Herzog TG. Hemolytic Uremic Syndrome presenting after treatment of endodermal sinus tumor. Obs Gyn 104:1184-7, 2004

66. Redlinger WFJ, Kissane J, Liapis H: Congenital bilateral renal arteriovenous malformation (AVM): An unrecognized cause of renal failure in children, (cover illustration: corresponding author) Ped Dev Path,

7(3):285-9, 2004 67. Rajaram V, Hill DA, Doherty GM, Liapis H, Dehner LP. Pleomorphic

rhabdomyosarcoma of the anterior wall following treatment for carcinoma of the rectum. Int J Surg Path 12(2):161-5, 2004

68. Liapis H, Foster K, Theodoropoulou E, Monga G, S. Pizzolitto Mazzucco G. Phenotype /genotype correlations in the ultrastructure of monogenetic glomerular diseases. Ultrast Path 28:181-197, 2004

69. Liapis H, Ho AK, Brown D, Mindel G, Gleich G. Thrombotic microangiopathy associated with hypereosinophilia syndrome. Kidney Int 67:1806-11, 2005

70. Tsirpanlis G, Moustakas G, Sakka E, Triantafylis G, Sotsiou F, Liapis H, Ziroyannis P. Catastrophic antiphospholipid syndrome in a young girl. Ped Nephrol 20:519-2, 2005

71. Rogers SA, Liapis H, Hammerman MR. Normalization of glucose post-transplantation of pig pancreatic anlagen into non-immunosuppressed diabetic rats depends on obtaining anlagen prior to embryonic day 35. Transpl Immunol 14(2):67-75, 2005

72. Lewin SN, Mutch DG, Whitcomb BP, Liapis H, Herzog TJ. Three cases of hemolytic uremic syndrome in ovarian cancer patients treated with combination gemcitabine and pegylated liposomal doxorubicin Gynecol Oncol 97:228-33, 2005

73. Slatopolsky E, Liapis H, Finch J. Progressive accumulation of lanthanum in the liver of normal and uremic rats. Kidney Int 68(6):2809-13, 2005

74. Rogers SA, Chen F, Talcott M, Liapis H, Hammerman

MR. Glucose tolerance

normalization following transplantation of pig pancreatic primordia into non-immunosuppressed diabetic ZDF rats. Transpl Immunol 16(3-4):176-84, 2006

75. Jain S, Suarez AA, McGuire J, Liapis H. Expression profiles of Congenital Renal Dysplasia Reveal New Insights in Renal Development and Disease. Ped Nephrol, 22 (7): 962-74, 2007

76. Price KL, Long DA, Jina N, Liapis H, Hubank M, Woolf AS, Winyard PJD. Microarray interrogation of human metanephric mesenchymal cells highlights potentially important molecules in vivo. Am J Physiol Physiological Genomics 28 (2):193-202, 2007

77.Solez K, Colvin RB, Racusen LC, Sis B, Halloran PH, Liapis H, etal: Banff ’05 Meeting Report and the Banff Classification of Renal Allograft Pathology, Eliminating “Chronic Allograft Nephropathy”, Am J Transplant 7(3):518-26, 2007

78.Mizobuchi M, Morrissey J, Finch JL, Martin D, Liapis H, Slatopolski E. Combination therapy with an angiotensin-converting-enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic rats. J Am Soc Nephrol. 8(6):1796-806, 2007

79. Liapis H and Tsokos GC. Pathology and Immunology of lupus nephritis. Can we bridge

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the two? Int J Urol Nephrol, 39(1):223-31, 2007 80.Gokden N, Cetin N, Colakoglu N, Kumar J, Abul-Ezz S, Barlogie S, Liapis H, Walker

PD. Morphologic manifestations of combined light chain deposition disease and light chain cast nephropathy. Ultrastruct Pathol, 31(2):141-9, 2007

81.Suh N, Liapis H, Misdraji S, Brunt EM, Wang HL. Epstein-BarrVirus Hepatitis: Diagnostic Value of In situ Hybridization, Polymerase Chain Reaction and Immunohistochemistry on Native Liver Biopsy from immunocompetent patients. Am J Surg Pathol, 31(9):1403-1409, 2007

82.De Petris L, Hruska KA, Chiechio S, Liapis H. Bone Morphogenetic Protein-7 delays Podocyte Injury due to High Glucose, Nephrol Dial Transplt 22(12):3442-3450, 2007

83.Gokden N, Barlogie B, Liapis H. Morphologic Heterogeneity of Renal Light Chain Deposition Disease. Ultrastr Pathol, 32:17-24, 2008

84.Driscoll JA, Bhalla S, Liapis H, Ibricevic A, and Brody SL. Autosomal dominant polycystic kidney disease is associated with an increased prevalence of bronchiectasis, CHEST,133(5):1181-8. 2008

85.Liapis H. Molecular Pathology of Nephrotic Syndrome in Childhood. A Contemporary Approach to Diagnosis. Pediatr Dev Pathol. 11(4):154-63, 2008

86.Holt DB, Liapis H, Mohanakumar T, Phelan DR, Gandhi SK, Huddleston CB, Canter CE. Complement fragment C4d and C3d deposition in Pediatric Heart Transplant Recipients with a Positive Crossmatch. J Heart Lung Transplant, 27(10):1073-8, 2008

87.Qunshan J, McDill BW, B Sankarapandian, Liapis H, Jeffrey B. Kopp, Lawrence B. Holzman, Mario R. Capecchi, Jeffrey H. Miner, Feng Chen. Targeted ablation of podocytes reveals their indispensable structural and signaling roles in glomerulogenesis. Am J Physiol Renal Physiol. 295(6):F1790-8, 2008

88.Studelska DR, Mandik-Nayak L, Zhou X, Pan J, Weiser P, McDowell LM, Lu H, Liapis H, Allen PM, Shih FF, Zhang L. High affinity glycosaminoglycan and autoantigen interaction explains joint specificity in a mouse model of rheumatoid arthritis. J Biol Chem. 23;284(4):2354-62 , 2009

89.Kedainis RL, Koch MJ, Brennan DC, Liapis H. Focal C4d + in Renal Allografts is Associated with the Presence of Donor Specific Antibodies and Decreased Allograft Survival. Am J Transplant. 9(4):812-9, 2009

90.Benway BM, Baca G, Bhayani SB, Das NA, Katz MD, Diaz DL, Maxwell KL, Badwan KH, Talcott MR, Liapis H, Cabello JM, Venkatesh R, Figenshau RS. Selective Versus Nonselective Arterial Clamping During Laparoscopic Partial Nephrectomy: Impact upon Renal Function in the Setting of a Solitary Kidney in a Porcine Model. J Endourol. 23 (7):1127-33, 2009

91.Lennerz JK, Spence DC, Iskandar SS, Dehner LP, Liapis H. Glomerulocystic kidney: one hundred year perspective. (cover illustration: corresponding author) Arch Pathol Lab Med. 134 (4):583-605, 2010

92.Surendran K, Selassie M, Stromberski C, McCright B. Liapis H, Krigman H, Kopan R.. Reduced Notch signaling leads to renal cysts and papillary microadenomas. J Am Soc Nephrol 21(5):819-32, 2010

93.Tripathi P, Guo Q, Wang y, Coussens M, Liapis H, Jain S, Kuehn MR, Capecchi MR, and Chen F. Axial Structures regulates kidney positioning but not nephrogenesis through Shh. Dev Bio 15;340(2):518-27, 2010

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94.Sis B, Mengel M, Mark Haas, Robert B. Colvin, Philip F. Halloran, Lorraine C. Racusen, Kim Solez, Liapis H etal. Banff ’09 Meeting Report: Antibody Mediated Graft Deterioration and Implementation of Banff Working Group. Am J Transplant. 10(3):464-71, 2010

95.Mizobuchi M, Nakamura H, Tokumoto M, Finch J, Morrisey J, Liapis H, Slatopolski E. Myocardial effects of VDR activators in renal failure. J Steroid Biochem Mol Biol.121 (1-2):188-92, 2010

96.Rogers SA, Mohanakumar T, Liapis H, Hammerman RC. Engraftment of cells from porcine islets of Langerhans and normalization of glucose tolerance following transplantation of pig pancreatic primordia in non-immune suppressed diabetic rats. Am J Path 177(2):854-64, 2010

97.Wang Y, Jarad G, Tripathi P, Pan M, Cunningham J, Martin D, Holzman LB, Liapis H, Miner JH, Chen F. Activation of NFAT signaling in podocytes causes glomerular sclerosis, J Am Soc Nephrol 21(10):1657-66, 2010

98.Jain S, De Petris L, Hoshi M, Akilesh S, and Liapis H. Expression profiles of podocytes exposed to high glucose reveal new insights into early diabetic glomerulopathy. (cover illustration: corresponding author) Lab Invest. 91(4):488-98, 2011.

99.Rogers SA, Tripathy P, Mohanakumar T Liapis H, Chen F, Talcott MR, Faulkner C, Hammerman MR. Engraftment of cells from porcine islets of Langerhans following transplantation of pig pancreatic primordia in non-immune suppressed diabetic rhesus macaques. Organogenesis, (3):154-62, 2011

100.Finch J, Suarez E, Husain K, Ferder L, Cardema M, Glenn D, Gardner D, Liapis H, Slatopolsky E. The Effect of Combining an ACE Inhibitor and a VDR Activator on Glomerulosclerosis, Proteinuria and Renal Oxidative Stress in Uremic Rats". Am J Physiol, Renal (1):F141-9, 2012

101.Chen YM, Marcos L, Liapis H, Steinberg TH, Morrison OR. An unusual cause of membranous glomerulonephritis in a patient with HIV. Int Urol Nephrol;44:983-6. doi: 10.1007/s11255-011-9945-6, 2012

102.McGuire JK, Harju-Baker S, Rims C, Sheen JH, Liapis H. Matrilysin (MMP-7) inhibition of BMP-7 induced renal tubular branching morphogenesis suggests a role in the pathogenesis of human renal dysplasia. J. Histochem Cytochem. 60 (3):243-53, 2012

103.Ryu M, Migliorini A, Miosge N, Gross O, Shankland S, Brinkkoetter PT, Hagmann H, Romagnani P, Liapis H, Anders HJ. Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury. J Pathol, 2012 May 3. doi: 10.1002/path.4046

104.Chatterjee R, Ramos E, Hoffman M, VanWinkle J, Martin d, Davis DK, Hoshi M, Hmiel SP, Beck A, Hruska K, Coplen D, Liapis H, Mitra R, Druley T, Austin P and Jain S. Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET signaling complex in a cohort of living US patients with urinary tract malformations. Hum Genet 131(11):1725-38, 2012 doi: 10.1007/s00439-012-1181-3

105.Darisipudi MN, Thomasova D, Kulkarni OP, Mulay SR, Liapis H, Anders HJ. Uromodulin triggers IL-1β-dependent innate immunity by activating the NLRP3

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inflammasome. J Am Soc Nephrol 23:1783-9, doi: 10.1681/ASN.2012040338, 2012. 106.Liapis H and Gaut JP. Renal biopsy in the era of genomics. Ped Nephrol (DOI)

10.1007/s00467-012-2356-9, 2012 107.Allam R, Scherbaum CR, Darisipudi MN, Mulay SR, Hägele H, Lichtnekert J,

Hagemann JH, Rupanagudi KV, Ryu M, Schwarzenberger C, Hohenstein B, Hugo C, Uhl B, Reichel CA, Krombach F, Monestier M, Liapis H, Moreth K, Schaefer L, Anders HJ. Histones from Dying Renal Cells Aggravate Kidney Injury via TLR2 and TLR4. J Am Soc Nephrol.23:1375-88. doi: 10.1681/ASN.2011111077, 2012

108.Mulay SR, Kulkarni OP, Rupanagudi KV, Migliorini A, Vilaysane A, Muruve D, Shi Y, Munro F, Liapis H, Anders HJ. Kidney stone disease: calcium oxalate crystals induce inflammation and acute kidney injury by activating NLRP3 inflammasome-mediated interleukin-1β secretion in renal dendritic cells. J Clin Invest. 2; 123:236-46. doi: 10.1172/JCI63679, 2013

109.Mulay SR, Thomasova D, Ryu M, Kulkarni OP, Migliorini A,Bruns H, Gröbmayr R, Lazzeri E, Liapis H, Romagnani P, Anders HJ. Podocyte loss involves MDM2-driven mitotic catastrophe. J. Pathol 230;322-335, 2013 DOI:10.1002/path.4193

110.Finch JL, Lee DH, Liapis H, Ritter C, Zhang S, Suarez E, Ferder L, and Slatopolsky E. The Effect of Phosphate Restriction on Mortality in Uremic Rats with Established Vascular Calcification. Kidney Int 2013 Dec;84(6):1145-53. doi: 10.1038/ki.2013.213.

111.Migliorini A, Angelotti ML, Mulay SR, Kulkarni OO, Demleitner J, Dietrich A, Shankland S, Sagrinati C, Ballerini L, Peired A, Liapis H, Romagnani P, Anders HJ. The antiviral cytokines IFN-α and IFN-β modulate podocytes and parietal epithelial cells: Implications for IFN toxicity, viral glomerulonephritis and glomerular regeneration. Am. J Pathol 2013 doi:pii: S0002-9440(13)00335-0. 10.1016/j.ajpath.2013.04.017

112.Gaut JP, Liapis H. IgA dominant post-infectious glomerulonephritis, pathology and insights into disease mechanisms. Diagn Histopath 2013 http://dx.doi.org/10.1016/j.mpdhp.2013.02.005http://dx.doi.org/10.1016/j.mpdhp.2013.02.005.

113.Chatterjee R, Hoffman M, Cliften P, Windus D, Seshan S, Liapis H, Jain S. An integrated clinicopathological and custom targeted multiplexed exome sequencing approach delineates genetic basis for atypical or complex presentation of Alport syndrome. PloS One 2013 10;8(10):e76360. doi: 10.1371/journal.pone.0076360.

114.Torosyan R, Anwar S, Liapis H, Morrison AR. Clinicopathological course of acute kidney injury following brown recluse (Loxoscles reclusa) envenomation. Clinical Kidney Journal 2013; doi: 10.1093/ckj/sft111

115.Peired A, Angelotti ML, Ronconi E, La Marca G, Mazzinghi B, Sisti A, Lombardi D, Giocaliere E, Della Bona M, Villanelli F, Parente E, Ballerini L, Sagrinati C, Wanner N, Huber TB, Liapis H, Lazzeri E, Lasagni L, Romagnani P. Proteinuria impairs glomerular regeneration by sequestering retinoic acid. J Am Soc Nephrol 2013 24:1756-68. doi: 10.1681/ASN.201209095.

116.Liapis H. Electron microscopy in kidney research: seeing is believing. Ultrastr Path 2013;37(5):340-5. doi: 10.3109/01913123.2013.810689.

117. Liapis H, Romagnani P, Anders HJ. New insights in podocyte death: mitotic catastrophe. Am J Pathol doi:pii: S0002-9440(13)00547-6. 10.1016/j.

118.Liapis H, Jain S. The Interface of Genetics with Pathology in Alport Nephritis. J Am Soc

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Nephrol. 2013 24(12):1925-7. doi: 10.1681/ASN.2013080913 119.Gaut JP, Hoshi M, Jain S, Liapis H. Claudin 1 and nephrin label cellular crescents in

diabetic glomerulosclerosis. Hum Pathol. 2014;45(3):628-35. doi: 10.1016/j.humpath.2013.10.030.

120.Roma AA, Amador-Ortiz C, Liapis H. Significance of isolated vasculitis in the gynecological tract: what clinicians do with the pathologic diagnosis of vasculitis? Ann Diagn Pathol. 2014;18(4):199-202. doi: 10.1016/j.anndiagpath.2014.

121.Haas M, Sis B, Racusen LC, Solez K, Glotz D, Colvin RB, Castro MC, David DS, David-Neto E, Bagnasco SM, Cendales LC, Cornell LD, Demetris AJ, Drachenberg CB, Farver CF, Farris AB 3rd, Gibson IW, Kraus E, Liapis H, Loupy A, Nickeleit V, Randhawa P, Rodriguez ER, Rush D, Smith RN, Tan CD, Wallace WD, Mengel M; as the Banff meeting report writing committee. Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions. Am J Transplant. 2014;14(2):272-83. doi: 10.1111/ajt.12590.

122. Ritter S, Zhang S, Finch JL, Liapis H, Suarez E, Ferder L, Delmez J,Slatopolski E. Cardiac and renal effects of Atrasentan in combination with enalapril and paracalcitrol in uremic rats. Kidney Bood Pressure Research. 2014;39(4):340-52. doi: 10.1159/000355811.

123.Thomasova D, Bruns H, Kretschmer V, Ebrahim M, Liapis H, Kotb A, Endlich N, Anders HJ. Podocyte MDM2 prevents p53-mediated podocyte loss and glomerulosclerosis. J Am Soc Nephrol 2014. Oct 14 pii: ASN.2014040345.

124.Maliakkal JG, Liapis H, White AJ, Ahn SY. C1q nephropathy in the setting of granulomatosis with polyangiitis treated with tacrolimus. Clin Kidney J. 2014: 499-500. doi: 10.1093/ckj/sfu087.

125.Kumar SV, Kulkarni OP, Mulay SR, Darisipudi MN, Romoli S, Thomasova D, Scherbaum CR, Hohenstein B, Hugo C, Müller S, Liapis H, Anders HJ. Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN. J Am Soc Nephrol. 2015 Feb 2. pii: JASN.2014070673.

126.Chen M, Liapis H. Focal Segmental Glomerulosclerosis: Molecular Genetics and Targeted Therapies. BMC 2015.

127.Mulay Shrikant R., Jyaysi Desai, Santhosh VR Kumar, Jonathan Eberhard, Dana Thomasova, Simone Romoli, Melissa Grigorescu, Bastian Popper, Volker Vielhauer, hristoph Reichel, Fritz Krombach, Martin Herrmann, Helen Liapis, Stefan Krautwald, Andreas Linkermann, Hans-Joachim Anders. Crystal-related cytotoxicity requires TNFR1-RIPK1-RIPK3-MLKL signalling. Nature in press

128.Anwar S, Larson DS, Naimi N, Ashraf M, Culiberk N, Liapis H, Wei C, Reiser J, Brennan DC. A case report of adrenocorticotropic hormone to treat recurrent focal segmental glomerular sclerosis post-transplantation and biomarker monitoring. Front Med (Lausanne). doi: 10.3389/fmed.2015.00013

129.Manson SR, Song JB, Guo Q, Liapis H, Austin PF. Cell Type Specific Changes in BMP-7 Expression Contribute to the Progression of Kidney Disease in Patients with Obstructive Uropathy. J Urol. 2015 Mar 23. pii: S0022-5347(14)04847-2. doi: 10.1016/j.juro.2014.10.117

130.Alvarez BS, Liapis H, Anders HJ. Links between coagulation, inflammation, regeneration and fibrosis in kidney pathology. Lab Inv in press

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131.Manda KR, Tripathi P, Hsi AC, Ning J, Ruzinova MB, Liapis H, Bailey M, Zhang H, Maher CA, Humphrey PA, Andriole GL, Ding L, You Z, Chen F. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence. Oncogene. 2015 Oct 19. doi: 10.1038/onc.2015.389.

132.Kumar Vr S, Darisipudi MN, Steiger S, Devarapu SK, Tato M, Kukarni OP, Mulay SR, Thomasova D, Popper B, Demleitner J, Zuchtriegel G, Reichel C, Cohen CD, Lindenmeyer MT, Liapis H, Moll S, Reid E, Stitt AW, Schott B, Gruner S, Haap W, Ebeling M, Hartmann G, Anders HJ. Cathepsin S Cleavage of Protease-Activated Receptor-2 on Endothelial Cells Promotes Microvascular Diabetes Complications. J Am Soc Nephrol. 2015 Nov 13. pii: ASN.2015020208.

Invited Publications:

1. Cryer P, Slone R, Whyte MP, Liapis H: Depression and Hypercalcemia CPC. Am. J.

Med. 101:111-117, 1996 2. Molecular pathology and tissue gene arrays in renal dysplasia. Hereditary kidney disease

update, 2003. Letters to the Editor:

1. Akilesh S, Jendrisak M, Zhang L, Lewis JS Jr, Liapis H. Acute Renal Allograft Thrombosis in “Seronegative” Antiphospholipid Syndrome, Nephrol Dial Transpl 2009

2. Red cell transverse through thin glomerular basement membranes. Kidney Int 61: (2):762-3, 2002

3. Liapis H, Dehner LP, Gutmann D. P53 in cellular / atypical neurofibromas. Am J Surg Pathol 23 (9), 1156-1157, 1999

Books / chapters

1. Diagnostic Pathology: Kidney diseases: 2nd edition, AMIRSYS, 2015.authored by R.B. Colvin, A Chang, B. Farris, N. Kambham, L. Cornell, R. Meehan, H. Liapis, S. Bonsib, S. Seshan, S. Jain and J Gaut.

- Alport syndrome - A-actinin deficiency - Collagenofibrotic glomerulopathy - Cystinosis - Diffuse mesangial sclerosis - Finish type nephropathy - Hereditary exostoses - Pierson syndrome - Podocin deficiency - Thin membrane disease - Type III hyperlipidemia - Lipoprotein glomerulopathy

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- Overview of Cystic Diseases - Muc-1 Disease - Nephronopthisis and related disorders - Nail-patella syndrome

2. Pathobiology of human Disease: A dynamic encyclopedia of disease mechanisms. H. Liapis section editor Kidney and Urinary tract, 1st edition Elsevier, 2014

3. Pathology of Solid Organ Transplantation: H. Liapis and H. Wang, 1st edition Springer,

2010 http://link.springer.com/book/10.1007/978-3-540-79343-4

4. Diagnostic Pathology: Kidney diseases: 1st edition, AMIRSYS, 2011 authored by R.B. Colvin, A Chang, B. Farris, N. Kambham, L. Cornell, R. Meehan, H. Liapis, S. Bonsib, S. Seshan, S. Jain and J Gaut.

Liapis H & Gaut JP

- Alport syndrome - A-actinin deficiency - Collagenofibrotic glomerulopathy - Classification of cystic kidney Diseases - Cystinosis - Diffuse mesangial sclerosis - Finish type nephropathy - Hereditary exostoses - Pierson syndrome - Podocin deficiency - Thin membrane disease - Type III hyperlipidemia - Lipoprotein glomerulopathy - Medullary Cystic kidney disease/Nephronopthisis - Nail-patella syndrome - Obstructive nephropathy - Classification of CACUT

Jain S & Liapis H - Dysplasia-Hypoplasia-Renal agenesis - Obstructive Nephropathy - Reflux nephropathy - Ectopia, malrotation, duplication, fusion, supernumerary kidney

5. Heptinstall’s Pathology of the Kidney, Liapis H and Winyard P: Chapter 4: Cystic Diseases of the Kidney and developmental defects. Edited by Jennette, Olson, Schwartz and Silva. Lippincott –Raven, 7th edition, 2014

6. Heptinstall’s Pathology of the Kidney : Liapis H, Gaut JP, Arend L: Chapter 22: Urinary tract infections/ Hydronephrosis / Reflux nephropathy, Lippincott –Raven, 7th edition, 2014

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7. The Washinghton of Surgical Pathology Manual 2nd edition 2011: Transplantation pathology of the kidney .Gaut JP & Liapis H. Lippincott –Williams & Wilkins 2st edition 2012

8. The Washinghton of Surgical Pathology Manual 2nd:Chapter 20 Surgical Diseases of the kidney–Maldevelopment and Non-neoplastic Cystic Diseases Hertel JD, Humphrey PA, Liapis H. Lippincott –Williams & Wilkins 2st edition 2012

9. The Washington of Surgical Pathology Manual: Chapter on Kidney pathology, (medical & non-neoplastic) edited by Humphrey PA, Dehner LP, Pfeifer JD. Lippincott –Williams & Wilkins 1st edition 2008

10. Heptinstall’s Pathology of the Kidney, Liapis H and Winyard P: Chapter 26: Cystic Diseases of the Kidney and developmental defects. Edited by Jennette, Olson, Schwartz and Silva. Lippincott –Raven, 6th edition, 2006

11. Heptinstall’s Pathology of the Kidney : Weiss MA and Liapis H: Chapter 22: Urinary tract infections/ Hydronephrosis / Reflux nephropathy, Lippincott –Raven, 6th edition, 2006

12. Contemporary Diabetes: The Diabetic kidney. Chapter 18: Hruska, KA, DePetris L, Li T, Wang S. Geurs T, Strebeck F, Chen Q and Liapis H. The prospect of a novel therapeutic, BMP7, in diabetic nephropathy. Edited by P Cortes and CE Mogensen, Humana Press 2006

13. Guest Editor: Seminars in Diagnostic Pathology: Rare, New and Variant glomerulopathies: A diagnostic challenge. August 2002

14. Atlas of renal pathology: Clinical Nephrology 2003 15. Renal Pathology Tutorial: H. Liapis, Tricia Pavlopoulos and Douglas Hamerski 2000 16. Nephropathology quiz pages Liapis H. Atheroembolic emboli: Int Urol Nephrol. 35(3):435, 43, 2003 17. Hassan A, Liapis H: Light chain deposition disease in kidney without evidence of

multiple myeloma: Int Urol Nephrol 35(4):579-80, 595-6, 2003 18. Liapis H. Fabry’s disease: Int Urol Nephrol 38 (2):361-2, 2006 19. Liapis H. Gouty nephritis: Int Urol Nephrol 38 (3-4):783-4, 2006 20. Liapis H, Kedainis R: Granulomatous interstitial nephritis. Int Urol Nephrol May 30,

2007 21. Liapis H, Young DO. Collapsing FSGS. Quiz Page Am J Kidney Dis: 49:A49-51, 2007

Invited Presentations:

1. Adhesion molecules in cancer. Kobé University School of Medicine, Department of Pathology, Kobe, Japan, April 22, 1994

2. The role of integrins in cancer progression and metastases. University Hospital of Zurich, Department of Pathology, Zurich, Switzerland, July 28, 1994

3. Avß3 (Vitronectin receptor) expression in breast cancer and breast cancer bone metastases. Technical University of Munich, Department of Pathology, Munich, Germany, August 5, 1994

4. Selective expression of the integrin "αvß3 by bone residing breast cancer metastases. American Society for Bone and Mineral Research, Kansas City, MO., September 12, 1994

5. Integrin expression in tumors of low malignant potential and invasive carcinomas of the

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ovary. XX International Congress of the International Academy of Pathology, Hong Kong October 10, 1994

6. The role of adhesion molecules in breast cancer; 5th Panhellenic Congress of Pathology; Ioannina, Greece, May 24, 1996.

7. P53 mutations and Ki-67 proliferative cell nuclear antigen in benign and MPNSTs in children. Annual Meeting of the Society of Pediatric Pathology /USCAP March 1, 1997

8. Adhesion molecules and their ligands in invasive and non-invasive breast adenocarcinoma: Euro Cell Path Society; May 13, 1997, Greece

9. Malignant peripheral nerve sheath tumors in children; utility of p53 and Ki-67 proliferating cell nuclear antigen in clinicopathologic assessment. European School of Pathology Pediatric Path Sessions, May 23, 1997, Greece

10. Expression of vitronectin and fibronectin receptors by pulmonary adenocarcinomas. USCAP, March 1998, Boston

11. The potential of gene therapy; animal models for kidney disease. May 1998, 6th Panhellenic Congress of Pathology, University of Alexandroupolis, May 21, 1998, Greece

12. Thin Membrane Disease variants versus Alport. Genetic analysis is important to specific diagnosis. USCAP, March 1999, San Francisco

13. Apoptosis and cell proliferation in experimental fetal obstruction. USCAP, March 1999, San Francisco

14. Viral infections in the renal allograft: Morphologic clues and utility of PCR. 5th Banff Conference on Solid Organ Allograft Pathology: June 8, 1999, Banff, Canada

15. Interpretation of the transplant renal biopsy. University of Athens, Dep. of Pathology and of Internal Medicine, May 17, 1999

16. Growth factors and their potential in the treatment of fetal hydronephrosis. Mothers and Babies research center, Washington University, St Louis, October 27, 1999

17. Growth factors in the North American opossum fetal kidney obstruction model. Institute of Child Health, University College London, November 25, 1999

18. Pathology and Pathobiology of Lupus nephritis. Univ. of Athens Medical School, departments of Immunology and Nephrology. February 7, 2000

19. Extracellular matrix in fetal kidney fibrosis following obstruction. USCAP March New Orleans, 2000

20. Ureteral obstruction in the fetal kidney. Washington Univ. Dep. of Medicine, Renal division, May 17, 200021. The role of Growth Factors in fetal kidney fibrosis. University of North Carolina, Chapel

Hill, Department of Pathology, May 25, 2000 22. Malignant pediatric kidney tumors in adults. University of North Carolina at Chapel Hill,

Department of Pathology, May 26, 2000 23. Molecular Pathogenesis of renal fibrosis. Renal Pathology Society, Companion meeting,

USCAP Atlanta, March 4, 2001 24. Unusual renal neoplasms: Clues to diagnosis and prognostic markers. Turin , Italy July

17, 2001 25. IgA Nephropathy, Pathology and pathogenesis. 5th BANTAO Congress, sponsored by

the International Society of Nephrology (ISN), October 3, 2001 26. The role of Electron microscopy in pediatric renal biopsy. Ultrastructural Pathology

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Society. March 1, Chicago, USCAP, 2002 27. Molecular pathology in congenital urinary obstruction. National Institute of Health 28. State of the Art Workshop, March 111-12, 2002 29. Gene chip arrays in dysplastic kidneys. Univ. of Athens, Dep. Ped. Nephrology, March

17,2002 30. Altered gene transcript profiles in congenitally obstructed human kidneys, USCAP,

Washington DC, March 24, 2003 31. Visiting Professor: University of Turin, Italy “Conrad Pirani” Lecturer: Pathobiology of

Lupus Nephritis and the New Classification, April 10-12, Turin, Italy, 2003 32. Atypical Hemolytic Uremic syndrome (HUS). University of Turin, April 12, 2003. 33. Visiting Professor: Renal pathology post-graduate course on kidney tumors. Slide

seminar, Unusual Kidney Tumors. Univ. of Ioannina, Greece, May 27, 2003 34. Molecular pathology in kidney neoplasia. Univ. of Ioannina, Greece May 28, 2003 35. Thrombotic Microangiopathies: A Differential Diagnosis. Univ. of Ioannina, Greece

May 28, 2003 36. Congenital obstructive nephropathy: Lessons from animal models. 37. Third International Congress of Nephrology organized by the Spanish Society,

November 2003 38. Novel genes in renal dysplasia. Univ. of Kansas (KUMU) Nephrology, August 26, 2004 39. Renal Pathology slide conference. KUMU Department of Pathology August 25, 2004 40. Ultrastructural pathology in genetic glomerular disease; contemporary implications.

International Academy of Pathology (IAP), Brisbane, Australia, October 15, 2004 41. Collagen IV α3-5 chain immunohistochemistry in human disease. USCAP in San

Antonio, Renal Pathology Society satellite meeting, February 2005 42. Global proteomics in dysplastic and normal developing kidneys. USCAP San Antonio,

Texas, February 2005 43. Genomics or Proteomics for congenital obstructive nephropathy. World Congress of

Hellenic Association of Biomedical scientists, Athens, Greece, May 16, 2005 44. Global Proteomics in obstructive nephropathy. European Congress of Pathology, Paris,

France, September 3, 2005 45. Mechanisms of Podocyte Injury in Response to High Glucose and Diabetes, American

Society of Nephrology, Philadelphia, November 10, 2005 46. Podocyte gene expression profiling in an in vitro model of diabetic nephropathy. United

States and Canadian Academy of Pathology, Atlanta, Georgia, February 15, 2006 and 6th international Podocyte Conference, Helsinki, Finland June 8-11, 2006

47. Cystic Diseases of the kidney. Visiting Professor Shanxi University China, April 8-14, 2006

48. Diagnostic challenges in Cystic Kidney Disease. Grand Rounds New York University, NY, June 22, 2006

49. Viruses and glomerular disease. 3rd World Congress on Quality in Clinical Practice: Thessaloniki, Greece, September 28-October 1, 2006

50. Pathology of Lupus Nephritis: an update. Saint Louis Children’s Hospital, Rheumatology division. December 7, 2006

51. Humorally (C4d) mediated rejection in lung transplantation. WU Lung transplant program, January 26, 2007

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52. Pathophysiology of Glomerular disease: University of Crete Graduate program March 6, 2007

53. Renal pathology for nephrologists and rheumatologists, University of Crete, Department of Medicine, March 5-7, 2007

54. Cystic kidney diseases; pathology and pathogenesis: University of Crete graduate program, March 7, 2007

55. Cystic Kidney Diseases: an update. Brigham Women’s Hospital, Boston, July 9,2007 56. Thin Membrane Disease: Two Diseases or One? Washington University St. Louis, Renal

Path Conference, March 16, 2007 57. Phenotype-Genotype correlations in monogenetic glomerular diseases. 14th International

Pediatric Nephrology Association, (IPNA) Budapest, September 1, 2007 58. Lipoprotein glomerulopathy. Nephropathology Working Group, 21st European Society of

Pathology (ESP) in Istanbul, September 12, 2007 59. Thin Basement Membrane Disease: Disease, lesion or both? 21st ESP in Istanbul, Pre-

congress Nehropathology symposium, September 8, 2007 60. Glomerulocystic kidney disease and glomerulocystic findings in renal biopsies:

Differential diagnosis and clinical relevance of pathologic findings. RPS-KUFA 4TH Satellite meeting, Istanbul, September 13, 2007

61. Visiting professor, Department of Pathology, University of Indiana, September 26-27, 2007

62. Light Chain Deposition Disease. The disease spectrum. Nephrology Grand Rounds, WU Renal Division, December 21, 2007

63. Collapsing glomerulopathy: Spanish Society of Nephrology, Madrid, Spain, April 2-6, 2008

64. Kidney Transplant Pathology: Banff 2007 classification update. Spanish Society of Nephrology, Madrid, Spain, April 5, 2008

65. Nephropathology symposium: Collapsing FSGS: a pattern or a disease? 3rd Intercontinental ESP meeting in Barcelona Spain, May 17-22, 2008

66. Renal Pathology Symposium, Molecular pathology of Congenital Nephrotic syndrome: IAP in Athens, October 17, 2008

67. Advances in Systemic Vasculitides and Vasculopathies. Anti-Phospholipid syndrome. IAP in Athens, October 15, 2008

68. Symposium on Biology of Kidney Maldevelopment: Bench and Bedside. The Transcriptome of Renal Dysplasia: American Society of Nephrology (ASN): Annual meeting, Philadelphia, November 9, 2008

69. Keynote speaker: Not all in Pathology is about Cancer. Kidney in Center Stage. Annual meeting of the Spanish Society of Pathology, Seville, Spain May 22, 2009

70. Moderator and speaker: Significance of focal C4d deposition, 10th Banff Conference, Canada, August 10, 2009

71. Co-Moderator symposium “Renal Diseases of Children in Adults” ASN 2009 in San Diego, California, October 31st.

72. Clinicopathologic conference, panelist. ASN 2009 in San Diego, California, October 31 73. NYU Grand rounds, May 17, 2010 Molecular pathogenesis of glomerular cysts 1ST RPS-

ESP International renal pathology Conference: Glomerulocystic kidney disease: Genomic insights. La Coruna, Spain June 9-12, 2010

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74. NKF-IPNA held in NYC August, 2010 75. IAP Brazil Workshop renal allograft pathology: donor biopsy. October 2010. 76. IAP Brazil, Short Course Chair: Infectious diseases and the kidney. October 2010 77. KUFA Council of Pediatric Nephrology and Urology, New York University, March 18,

2011 78. University College London, Clinicopathologic conference at Children’s Hospital at Great

Ormond street. Pediatric Cystic kidney disease on renal biopsy. March 21, 2011 79. 11TH Banff conference in allograft pathology, Paris chair: Pre-implantation biopsy

working group update, June 7, 2011 80. Nephrology forum, Heidelberg, Germany. The Podocyte in Diabetes. December 9, 2011 81. Ludwig Maximilian University (LMU)-Nephrology, Munich, Germany: Podocytes

exposed to high glucose in vitro. December 6, 2011 82. 54th Annual Congress of the Mexican Society of Pathology Queretaro, Mexico, plenary

session “Antibody mediated transplant rejection”. May 1-4th, 2012 83. 54th Annual Congress of the Mexican Society of Pathology Dual glomerular disease in

renal allograft biopsies. May 1-4th, 2012 84. Ultrastructural Pathology, Scanning and freeze fracture electron microscopy: correlation

with transmission electron microscopy in kidney disease pathogenesis, Regensburg, Germany, August 4-10, 2012

85. BANFF 2013. Implantation biopsy consensus guidelines. 8-20-13, Brazil. 86. Congenital & Infantile nephrotic Syndrome, Pediatric Nephrology 41st year Seminar,

Guest Faculty, University of Miami, Miller School of Medicine, March 6, 2014 87. Mitotic catastrophe: An unrecognized cause of Podocyte Death. WU Renal Research

Conference, Jan 29, 2014 88. Pediatric Cystic Diseases: Pathology. Pediatric Nephrology 41st year Seminar, Guest

Faculty, University of Miami, Miller School of Medicine, March 7, 2014 89. Congenital & Infantile Nephrotic syndrome: Pediatric Nephrology 41st year Seminar,

Guest Faculty, University of Miami, Miller School of Medicine, March 6, 2014 90. Pediatric Cystic Disease on renal biopsy, Pediatric Nephrology 41st year Seminar, Guest

Faculty, University of Miami, Miller School of Medicine, March 8, 2014 91. Clinicopathologic conference at Children’s Hospital at Great Ormond street. University

College London, Pediatric Renal biopsy. March 31, 2014 92. Molecular Pathology of the Nephrotic Syndrome. Washington University course:

Surgical pathology in the Genomic era. May 5,2014 93. Role of next generation sequencing in diagnosis of hereditary renal diseases. IAP

Bangkok, October 6-10, 2014 94. Past, Present and Future of the Banff group on classification of kidney allograft rejection.

Epson & St. Helier University Hospitals NHS Trust. December 19, 2014. 95. Congenital & Infantile Nephrotic syndrome: Pediatric Nephrology 42st year Seminar,

Guest Faculty, University of Miami, Miller School of Medicine, March 5-7, 2015 96. Pediatric Cystic Diseases: Pathology. Pediatric Nephrology 42st year Seminar, Guest

Faculty, University of Miami, Miller School of Medicine, March 5-7, 2015 97. Fabry’s and other metabolic diseases in children. University of Miami, Miller School of

Medicine, March 5-7, 2015 98. Recurrent and de novo glomerular disease in children. University of Miami, Miller

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School of Medicine, March 5-7, 2015 99. Congenital membranous. University of Miami, Miller School of Medicine, March 5-7,

2015 100. BANNF 2015. Chair and speaker on Donor biopsy pathology final report. 101. ISSRP, Bari, Italy, July 29-31, 2015. Teaching Faculty. 102. ASN 2015 San Diego. Moderator: Not Just Another Cell in the Glomerulus: The

Emergence of the Parietal Cell. Moderator. 103. Alexion Internal Education forum. NYC August 18-19, 2015 104. Hara M, Liapis H. Mitotic Catastrophe in diabetic Nephropathy. Oral presentation. ASN

November 2015 105. 16th Prague Postgraduate Training Course in Nephrology, January 22-23, 2016. 106. When to add molecular genetics for renal biopsy diagnosis? 107. Registries and nephropathology; is there difference between Europe and US?

University of Miami, Miller School of Medicine, Pediatric Nephrology Seminar XLIII and Renal Pathology Course, March 9-10, 2016

108. Annual Pathology Conference, Mexico City, March 11-12, 2016. 109. IPNA 2016. Congenital and Infantile Nephrotic Syndrome

C1q nephropathy The spectrum of pediatric Cystic Kidney diseases Pathology and molecular genetics GU anomalies (CAKUT): a field mature for molecular genetics?

Organizational / educational activities in National/International societies/organizations

1. 5th Banff International Conference on Organ Transplantation, 1999. 2. American Society of Nephrology: Renal biopsy interpretation for nephrologists, 1999-

2005 3. Society of Pediatric Pathology (SPP) and the United States and Canadian Academy of

Pathology (USCAP). Workshop in pediatric renal biopsy pathology, 2000, 2001, 2002. 4. USCAP - Renal Pathology Society: Publications /communications committee 2000-2003 5. 5th BANTAO Congress organizing committee: Chair, symposium on Renal pathology;

clinicopathologic correlations, under COMGAN (commission on advancement of nephrology worldwide), Thessaloniki, 2001.

6. RPS communications committee 2001-2003) 7. Congenital Urinary Obstruction. State of the art workshop, moderator, NIH, Bethesda,

March 11-12, 2002 8. Am Society of Nephrology (ASN) Co-moderator, symposium on “Advances in our 9. Understanding of congenital renal disease: molecular and genetic approaches”. 36th

Annual Meeting in San Diego, Nov 16, 2003 10. American Society of Nephrology (ASN) Abstract reviewer Clinical Renal Pathology /

Laboratory Medicine, 2003 11. ASN Clinicopathologic Conference, November 2004, St Louis 12. Renal Pathology Society scientific and program committee for USCAP and ASN 2004-

06 meetings

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13. Chair symposium “Renal biopsy interpretation in medical glomerular diseases and transplantation" Nafplion, Greece February 10-12, 2005

14. Chair symposium “Biology of Kidney Disease” 8th World Hellenic Biomedical Congress, Athens, Greece May 16, 2005

15. Renal Pathology Society Secretary Treasurer April 2005-present 16. Chair: Renal pathology practices around the world: 3rd World Congress on Quality in

Clinical Practice: Thessaloniki, GR, September 28-October 1, 2006 17. ASN abstract reviewer 2006 18. Chair Conference: Renal biopsy interpretation. Controversies and Challenges.

Washington University, St. Louis, March 16, 2007. 19. Visiting professor Graduate Program "Cellular and Genetic Etiology, Diagnosis and

Treatment of Human Diseases" University of Crete department of Medicine, March 5-7, 2007

20. Chair: Free communications Genetics session,14th International Pediatric Nephrology Association, annual meeting, Budapest, Hungary, September 1, 2007

21. Visiting professor, Department of Pathology, University of Indiana, September 26-27, 2007

22. External reviewer pathology faculty promotion committee at Brown University, October 2008

23. Co-Chair: Hematuria and the Nephritic Syndrome: RPS/SLANH Renal pathology course native kidney diseases. Mexico City, April 15-16, 2009

24. External faculty promotion committee University College London, United Kingdom, 2009

25. Elected Renal Pathology Society Councilor, March 2010 26. Program Committee, 1st International Renal Pathology Meeting, La Coruña, Spain, June

9-12, 2010 27. Elected to the Executive Committee Faculty Council (ECFC) Washington University St.

Louis 2010-13 28. United States and Canadian Academy of Pathology Scientific Review Board Abstract

Committee 2011-2013 29. USCAP Ambassador: mentoring the next generation of pathologists 2011-2016 30. ASN Kidney week 2012 Co-moderator Basic and Clinical science symposium on

Congenital anomalies of the kidney and the Urinary tract (CAKUT), Nov 4, 2012, San Diego

31. ASN Postgraduate education committee (PGE) committee 2013-2016 32. RPS president 2014 33. IPNA chair of Renal pathology course, September 2016, Igarassu, Brazil.

Consultation Medical renal biopsies submitted by local/national/international nephrologists Interdepartmental consults for medical and transplant kidneys Medicolegal consultations Biomedical Systems ATLAS Lupus study, October 2011- present.

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Alexion August 2015-present. Abstracts:

1. Giamarellou H, Liapis-Tsiroyianni H: LY12735 and RO139904: New spectrum Cephalosporins; Comparative activity with Cefuroxime-Cefsulodin-Cefotaxime and Cephalothin. Proceedings of Second Mediterranean Congress of Chemotherapy, Oct. 13-16, 1980.

2. Mandyla H, Liapis H, Xanthou M: Changes of human milk leukocytes, during various processes of milk storage. Proc. International Symposium on New Aspects of Nutrition in Pregnancy, Infancy and Prematurity. Athens, Greece, Oct. 3-4, 1986,

3. Larson R, Rudloff M, Liapis H, Davila R., Manes J, Kissane J: The Ivemark syndrome: a rare cystic lesion with syndromic associations. Polycystic Kidney Disease Research Foundation, Kansas City, Missouri, June 19-21, 1992.

4. Liapis H, Gersell D, Roby J, Rader J: In situ localization of parathyroid hormone-like protein and mRNA in carcinomas of the uterine cervix from normocalcemic and hypercalcemic patients without bone metastasis. Lab Invest 68:75A (#429), 1993

5. Liapis H, Crouch EC, Kissane JM, Davila RM: PDGF-A chain and type I collagen mRNAs are abnormally distributed and overexpressed in congenital renal dysplasia. Pathol. Res. Pract. 189:741 (#6-7), 1993

6. Liapis H, Davila RM, Roby J, Parks WC: Erythropoietin is expressed by eosinophils in human liver and kidney. Lab Invest 70(1):159A, 1994

7. Liapis H, Civitelli R: PTHrp effects on growth of MCF-7, ZR-75, T-47D and MDA-MB-231 breast cancer cells in culture. Third International Conference on New Actions of Parathyroid Hormone. Kyoto, Japan, April 1994.

8. Liapis H, Teitelbaum S, Kitazawa S, Smith JW, Merkel K, Ross FP: Selective expression of the integrin αvß3 by bone-residing breast cancer metastases. J. Bone Min. Res. 9:146 (#A102), 1994

9. Liapis H, Hutton K, Wick MR, Chan I, Rader J: Integrin expression in borderline and invasive ovarian carcinoma. XX International Congress of the International Academy of Pathology and 11th World Congress of Academic and Environmental Pathology. Hong Kong, October 9-14, 1994

10. Steinhardt G, Liapis H, Vogler G, Yoon P: Insulin-like growth factor improves renal architecture in fetal kidneys with complete unilateral ureteral obstruction. American Academy of Pediatrics, Dallas, TX, October 22-26, 1994

11. Adler LM, Liapis H, Rader JS: Comparison of integrin expression and clinical characteristics in ovarian carcinomas and tumors of low malignant potential. 20th Annual Meeting of the Society of Gynecologic Oncologists. San Francisco, CA, February 22, 1995

12. Liapis H, Davila RM, Flath A, Smith JW: Developmental expression of "vß3, "vß5, and "5ß1 integrin receptors in fetal and adult human kidneys. Lab Invest 72(1):160A (#935), 1995

13. Liapis H, Flath A, Smith JW: Tubular epithelial integrins are downregulated in cystic renal dysplasia. Lab Invest 72(1):160A (#936), 1995

14. El-Mofty S, Liapis H, Swanson P, Flaris N, Roberts R: Psammomatoid ossifying

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fibroma, cemento-ossifying fibroma and ossifying meningioma: comparative histogenesis. Annual Meeting, American Academy of Oral and Maxillofacial Pathology, Colorado Springs, Colorado, May 6-9, 1995.

15. Liapis H, Flath A, Sudbeck BD: Coexpression of vitronectin receptor ("vß3), 92-kD (MMP-9), and 72-kD (MMP-2) metalloproteinases in breast cancer metastasis to bone. Pathology Research & Practice 191(7 & 8):713,1995

16. Liapis H, Swanson PE, Flath A, Steinhardt GF: Phenotype of activated interstitial cells in fetal opossum kidneys. Pathology Research & Practice 191(7 & 8):713,1995

17. Urban J, Liapis H, Merkel K, Teitelbaum S, Krukowski M, Miller: Sequential appearance of proteins in single distraction osteogenesis specimens. American Society for Bone and Mineral Research, Baltimore, MD, September 11, 1995.

18. Ritter JH, Wick MR, Dresler CM, Liapis H: Expression of the vitronectin and fibronectin receptors by pulmonary adenocarcinomas: an immunohistologic study. ASCP/CAP Meeting, New Orleans, LA, September 16-22, 1995

19. Yianopoulou I, Nakopoulou L, Liapis H, Davaris P: Localization of stromelysin 1 (MMP-3) mRNA in breast cancer: Comparison with MMP-1 and MMP-3 protein expression and correlation with clinical parameters. 5th Panhelleic Congress of Pathology, A 67, page 141 in Congress proceedings, May 1996

20. Liapis H, Marley EF, Lin X, Dehner LP: p53 mutations and Ki-67 proliferating cell nuclear antigen in benign and malignant peripheral nerve sheath tumors (MPNST) in children. Lab Invest 76(1) 4p (20A), 1997

21. Liapis H, Nag M, Kaji D.M: K-CL co-transporter is highly expressed in distal tubular epithelium of the human kidney. J Am.Soc Nephrol. 8:38A,1997

22. Rader JS, Gerhard JS, O’Sullivan MJ, Li, MJ, Li Y, Liapis H, Huettner PC: Chromosomal deletions in CIN III of the cervix. Annual meeting of Gyn-Oncol, 1997

23. Tiniakos D, Yu, H, Liapis: Osteopontin expression in ovarian carcinomas and tumors of low malignant potential. Lab Invest 76 (1)111A, 1997

24. Tiniakos D, Yu H, Liapis, H: Extracellular matrix proteins in ovarian carcinomas and tumors of low malignant potential. Lab Invest 76 (1) 110A,1997.

25. Ritter JH, Wick MR, Dresler CM, Liapis H: Expression of the Vitronectin and fibronectin receptors by pulmonary adenocarcinomas: An immunohistologic study. United States and Canadian Academy of Pathology, March 1998, Boston

26. Liapis H, Yu H, Steinhardt GF: Apoptosis and Bcl-2 in experimental fetal obstruction. 7th International Workshop on Developmental Nephrology. Stockholm, Sept 9-11, 1998

27. Kaji D.M. and Liapis H: Expression of K-CL co-transport (KCC1) in human tissues. J. ASN. 9:37A,1998

28. Liapis H, Godken N, Cole B, Miner J: Thin Membrane Disease variants vs Alport. Genetic analysis is important to specific diagnosis. IAP, San Francisco, March 1999

29. Liapis H, Steinhardt G .F: Apoptosis and Cell proliferation in experimental ureteral obstruction. USCAP, San Fransisco, March 1999

30. Miner JH, Andrews KL, Betsyuaku T, Shipley MJ, Liapis H, Senior RM: Gelatinase B and Laminin b2 mutations alter the progression of Alport nephritis. International workshop on Alport syndrome. Utah, April 15-17, 1999

31. Levy NT, Eisenberg PR, Botney MD, Liapis H, Trulock EP: Resolution of Primary

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pulmonary hypertension in left native lung, following right single lung transplantation. Am J Resp Crit Care 159: (30A157-A157) S, 1999

32. Marley E, Zhang H, Guttman D, Liapis H :P53, P21, Mib-1, MAPK and Rb expression in plexiform neurofibromas and MPNSTs. USCAP, New Orleans March 25, 2000

33. Rader JC, Koki AT, Edwards D, Masferrer J, Mutch DG, Liapis H: Cyclooxyganase-2 expression in Uterine and Ovarian Cancers. Gyn Onc, 2000

34. Afify A, Liapis H, Werness B: Expression of p53, p21 and Ki-67 in papillary serous carcinomas and serous tumors of low malignant potential. Lab Inv 80(1), 119A #693, 2000

35. Liapis H, Zhang H, Steinhardt GF: Extracellular matrix in fetal kidney fibrosis following obstruction. USCAP, New Orleans, 2000

36. Liapis H, Storch G, Hill A, Rueda H, Singer G, Brennan D: Tissue, Blood CMV-PCR and renal pathology in allograft biopsies. Int Transplt Soc, Rome, Italy, Aug 2000

37. Liapis H, Barent B, Rieckenberg C: Phenotype and function of fetal kidney fibroblasts in response to growth factors. JASN (11) 387A, 2000

38. Rogers SA, Liapis H, Hammerman MR: Transplantation of metanephroi across the major histocompatibility complex in rats. JASN (11) 382A, 2000

39. Hruska KA, Chen Q, Liapis H, Chauddhary L, Wozniac M, Klahr S, McCartney JM, Sampath K, Morrissey J: BMP7 protects tubulointerstitial fibrosis and preserves GFR in chronic kidney disease. JASN (11) 629A, 2000

40. Hruska KA, Chen Q, Liapis H, Chaudhary L, Wozniac M, Klahr S, McCartney J, Sampath K, Morrissey J: Kidney tubulointerstitial disease is treatable with BMP -7 in a rat model. JASN (11) 620A, 2000

41. Afify A, Liapis H, Werness B. Expression of p53, p21 WAF1/C1P1 and Ki-67 in papillary serous carcinomas and serous tumours of low malignant potential. Lab Invest 80 (1), 693A, 2000

42. Gokden N, Ehrig T, Barbatis C, Liapis H: CD44s, V5, 6, 7, 8 are differentially expressed in renal cell carcinomas. Mod Path, 14 (1), 631A, 2001

43. Cozzolino M, Dusso A, Liapis H, Finch J, Burke S, Slatopolsky E. Advantage of sevelamer hydrochloride (RenalGel) over calcium carbonate on ectopic calcification in uremic rats. JASN (12)762 A, 2001

44. JM Pullman, CC Nast, Ferrario F and the renal path society: Renal biopsies: Standards for adequacy and evaluation. JASN (12),735A, 2001

45. Morrissey J, Fitzgerald M, Guo Guangie, Moridaira K, Tolley T, Liapis H, McCracken R, Klahr S. During the progression of renal fibrosis endogenous endostatin formation leads to decreased peritubular capillaries. JASN (12) 515A, 2001

46. Doshi R, Liapis H, Steinhardt G.: Renin localization in multicystic dysplastic kidneys associated with infant hypertension. Am Acad of Ped, annual meeting October 2001

47. Morrissey J, Fitzgerald M, Moridaira K, McCracken R, Tolley T, Liapis H, Klahr S 48. ACE inhibition blunts endogenous endostatin production in renal fibrosis. FASEB

Journal16 (4): A121_A121 Part 1, 2002 49. Cozzolino M, Dusso A, Liapis H, Finch J, Staniforth M, Burke S, Slatopolski E.

Sevelamer hydrochloride prevents high phosphorus-induced vascular calcifications in long-term experimental uremia. J Am Soc Nephrol (13) 579A, 2002

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50. Wang S, Chen Q, Eisenbeis P, Strebeck F, Liapis H, Idelburg C, Morrissey J, Klahr S, Hruska KA. Bone morphogenetic protein 7(BMP7) an effective therapy for chronic kidney disease (CKD). J Am Soc Nephrol (13) 45A, 2002

51. McGuire JM, Parks WC, Liapis H. Matrilysin expression in human cystic disease. J Am Soc Nephrol (13), 537A, 2002

52. Cruz RC, Steinhardt GF, Liapis H, et al. The role of matrix metalloproteinases (MMPs) 53. in unilateral ureteral obstruction (UUO) in newborn rats. FASEB J 16 (5): A1097 Part 2,

2002 54. Suarez A, Steinhardt GF, Liapis H: Altered gene transcript profiles in congenitally

obstructed human kidneys. Lab Invest (83), A1227, 2003 55. Liapis H, Rajaram V, Beck A, Brennan D. C4d expression in pediatric renal transplant

biopsies. Nephrol Dial Trans vol 18, p294 (T33A), 2003 56. Charonis A, Liapis H. Differential expression of endothelin receptors in the developing

kidney following unilateral ureteral obstruction. European Renal cell Biology, Venice, March 12, 2003

57. Drakopoulos A, Charonis A, Vlachoyiannis J, Liapis H. Differential expression of endothelin receptors and increased extracellular matrix synthesis in the developing kidney following unilateral ureteral obstruction in the opossum. Nephrol Dial Transpl Vol 18 Supplement, p 281(M878A), 2003

58. Liapis H, Niederhoff RA, Sotelo AK, Suarez AA, Weitraub SJ. Cytokine induction in tubular epithelial cells under mechanical tension. JASN, San Diego, 2003

59. Suarez AA, Matthew S, Hruska K, Liapis H. BMP7 expression is decreased in human chronic kidney disease. USCAP, February 28, Vancouver, Canada 2004

60. Niederhoff RA, Sotelo AK, Suarez AA, Liapis H, Wientraub SJ. Regulation of Cytokine and Apoptotic Regulatory protein expression in proximal tubular epithelial cells under mechanical tension. Am Urologic Association (AUA), March 2004

61. Yang J, McDill BW, LiapisH, Miner JH, Holzman LB, Chen F. Regulation of kidney development. J Am Soc Nephrol (15) 523A, 2004 62. McGuire J, Liapis H, Suarez A, Hruska K. Matrilysin (MMP7) is expressed in Renal 63. Dysplasia and inhibits Bone Morphogenetic Protein 7 (BMP7) induced tubulogenesis.

J Am Soc Nephrol (15) 818, 2004 64. Alvarez G, Malone J, Gross J , Townsend R, Liapis H. Global proteomics in dysplastic

and normal fetal kidneys. Lab Inv 85, A1225, 2005 65. Alvarez G, Liapis H, Wang HL. Late onset centrilobular necrosis in liver allografts:

does humorally mediated rejection play a role? Lab Inv, A, 2006 66. Suh N, Liapis H, Misdraji J, Brunt EM, Wang HL. Epstein-Barr Virus Hepatitis: 67. Diagnostic Value of Immunohistochemistry, In Situ Hybridization and Polymerase Chain

Reaction on Liver Biopsy Abstract #1301 USCAP in Atlanta, February 2006 68. De Petris l, Jain S, Hruska K, Liapis H. Podocyte gene expression profiling in an in

vitro model of diabetic nephropathy. Lab Inv, 2006 69. De Petris L, Thomas DB, Liapis H, Barisoni L. Dystroglycan (DG) protein expression

and gene transcription in minimal change nephrosis (MCN) and focal segmental glomerulosclerosis (FSGS). 6thInternational Podocyte Conference, Biomedicum, Helsinki, Finland June 8-11, 2006.

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70. Mizobuchi M, Morrissey J, Finch J, Liapis H and Slatopolsky E. Combination therapy with an angiotensin-converting-enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic rats. ASN Annual meeting San Diego, CA November 18, 2006.

71. Bantle E, Ritter RH, Trulock EP and Liapis H.C4d Deposition in Lung Allograft Biopsies: Detection by immunohistochemistry and correlation with anti-donor serum antibodies, histology and patient outcome. USCAP, San Diego, CA, March 2007.

72. Holt BD, Liapis H, Phelan DR, Gandhi ACD,SK, Huddleston MD, Canter CE. Complement Fragments C4d and C3d deposition does not correlate with rejection in pediatric heart transplant recipients with a positive cross-match. The international Society of Heart and Lung Transplantation 27th annual meeting, San Francisco, CA, February 2007

73. Ohashi R, Zhang W, Liapis H. Phenotypic podocyte profiles in HIV infected patients with glomerulonephritis subjected to anti-viral therapy. ASN San Francisco, CA November 2007

74. Santosh S, Kedainis, R, Liapis H Vijayan A. The changing face of lupus nephritis: review of biopsies from 1997-2007, F-PO998, ASN San Francisco, CA November 2007.

75. Kedainis R, Koch M, Liapis H. Detection of C4d Deposits in renal allografts: A single center experience. F-PO650, ASN San Francisco, CA, November 2007.

76. Driscoll JA, Ibricevic A, Bhalla S, Liapis L, Brody SL. Autosomal dominant polycystic kidney disease is associated with an increased prevalence of bronchiectasis. ATS 2008

77. Spence D, Dehner LP, Liapis H. PAX-2 and Tamm-Horsfall Immunohistochemistry Facilitate the Diagnosis of Glomerular Cysts in Bilateral Cystic Kidneys," abstract #1511, to the United States and Canadian Academy of Pathology's 97th Annual Meeting, March 1-7, 2008

78. Sarabu N, Ritter CS, Boudreaux S, Arcidiacono MV, Slatopolsky E, Liapis H, Brown AJ. Expression and Potential Functions of the Calcium-sensing Receptor in the Adrenal Gland. ASN, Nov 2008

79. Lennerz JK, Jain S and Liapis H. In silico study of glomerular cyst pathogenesis. USCAP Boston, 2009

80. Liu Ta-Chiang and Liapis H. Thin Glomerular Basement Membrane: Histopathologic, Ultrastructural and Molecular Variability. USCAP 2010, Washington DC, March 22, 2010

81. Finch J, Suarez E, Husain K, Feder L, Cruz M, Glenn D, Gardner D, Liapis H, Slatopolsky E. The effect of combining an ACE inhibitor and a VDR activator on glomerulosclerosis, proteinuria and renal oxidative stress in uremic rats. ASN 2010

82. Jain S, Ramos E, Druley T, Hruska, KA, Austin P, Hmiel P, Beck A, Coplen D, Mitra R, Liapis H. Genetic analysis by targeted and whole exome sequencing reveals multiple deleterious variants in CAKUT patients. ASN, 2010

83. Gaut J, Shen J, DeGuire M, Klein C, Liapis H. Acute Glomerulitis with neutrophils may underscore the development of glomerular basement membrane multi-Lamination in transplant glomerulopathy. #2468 United States and Canadian Academy of Pathology's 100th Annual Meeting, February 26 - March 4, in San Antonio, TX. 2011

84. Roma A, Amador-Ortiz C, Liapis H. Significance of gynecologic vasculitis. USCAP in

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San Antonio, TX 2011 85. Gottipati S, Wagner S, Vasquez-Martel E, Gaut J, Liapis H. Transplant glomerulopathy

and dual disease: An uncommon occurrence in renal allograft biopsies USCAP in Vancouver, 2012

86. Karnes HE, Gaut JP, Takasu O, Liapis H. the clinicopathol;ogic spectrum of rhabdomyolysis and KIM1 immunohistochemistry in patients with acute kidney injury. USCAP in Vancouver, 2012

87. Younberg G, LiapisH. Alport-like Changes in Allograft Glomerular Basement Membranes: a Peculiar Manifestation Occurring early post-transplan in a Pediatric Donor-Adult Recipient Renal Transplantation USCAP in Vancouver, 2012

88. Vijayan A, Liapis H. "Changing Spectrum of Lupus Nephritis: Eight Year Data From a Tertiary Referral Center", for the 2012 ACR/ARHP Annual Meeting.

89. Thomasova D, Bruns HA, Lozano G, Liapis H, Anders HJ. Lack of murine double minute (MDM)-2 in podocytes causes autophagic cell death and focal segmental glomerulosclerosis. ERA-EDTA May 2013 annual meeting.

90. Slatopolsky E, Ritter C, Finch JL, Liapis H, Suarez E, Ferder L, Delmez J and Zhang S. Protective Effects of Enalapril, Atrasentan and Paricalcitol on Glomerulosclerosis, Proteinuria and Cardiac Oxidative Stress in Uremic Rats . ASN 2013

91. Anwar S, Naimi N, Ashraf M, Liapis H, Jarad G, Brennan DC. Concurrent and sequential analysis of Glomerular albumin permeability, Soluble urokinase receptor, and Angiotensin 1 receptor antibody in a renal transplant recipient with recurrent Focal Segmental Glomerular Sclerosis. ASN 2013

92. IgA Nephropathy Precipitated after Hemi-Hepatectomy for Colorectal Metastasis. Anwar S, Larson S, Ashraf M, Liapis H, Morrison A. ASN 2013

93. Patel KR, Liapis H, Gaut JP. Genotype-phenotype correlation in a case of infantile steroid resistant nephrotic syndrome. SSP 2014

94. Gaut JP, Hoshi M, Jain S, Liapis H. Claudin-1 and Nephrin Label Cellular Crescents in Diabetic Glomerulosclerosis. USCAP 2014, San Diego, CA

95. Chen Y, Zhou Y, Gaut JP, Liapis H. Podocyte loss in diabetic glomerulosclerosis. USCAP 2014, San Diego, CA.

96. Chrisinger JA, Gaut JP, Jain S, Liapis H. Podocyte death in glomerulonephritis. USCAP 2014, San Diego, CA.

97. Thomasova D, Bruns H. A., Kretschmer V, Ebrahim M., Liapis H., Kotb A., 98. Endlich N, Ander H.-J. MDM2 in Podozyten verhindert den durch p53-Überexpression-

vermittelten Zelltod (Podoptose), Proteinurie und Glomerulosklerose 99. Annual German Soc of Nephrology meeting, Berlin. September 2014. 100. Liapis H. Role of next generation sequencing (NGS) in the diagnosis of hereditary renal

disease. IAP 214 Bangkok. 101. Mutneja A, Cossey N, Liapis H, Cheny. Thrombotic Microangiopathy secondary to

multicentric Castleman’s disease. ASN 2014 102. Anwar S, Liapis H, Brennan D. Novel Use of Masitinib for Recurrent Familial

Interstitial Nephritis Post Renal Transplantation. ASN 2014 103. Liapis H. Boils C, Gaut JP, Hennigar R. Silva F. Immunohistochemical Analysis of

Myoglobin Cast Nephropathy in Renal Biopsies. USCAP 2015, Boston, March 25, 2015.

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104. Hara M, Liapis H. Mitotic Catastrophe in diabetic Nephropathy. ASN November 2015

TEACHING 1982-1985 General and Organ Pathology medical student course; St Louis University, St

Louis, MO Inflammation Bone pathology Cardiac pathology, including congenital heart disease OB-GYN pathology Prostate Kidney

1986-87 Transfusion Medicine, Athens, Greece 1988 Renal Pathology weekly conferences, St Louis University, St Louis, MO 1991-93 Transfusion Medicine, weekly resident conferences 1991-93 Endocrine pathology and metabolic bone diseases: Washington University (WU) School of Medicine, Sophomore Pathology Course 1994-present Cardiovascular and Urinary pathology, including kidney: WU Sophomore

Pathology Course 1996-2014 Renal pathology section of the WU pathology course to Sophomore med students 1996 Molecular techniques in Pathology 1994-2014 Renal pathology: biannual specialty conferences WU pathology residents 1994-2014 Renal pathology: weekly Clinicopathologic Nephrology Conference 1994-2014 Gross organ pathology (Monday morning conference for 1st and 2nd year

residents) 1994-2014 Unknown glass slide conference (Tuesday morning conference for all path

residents and fellows) 2004-2014 Nephrology fellow curriculum lectures 2008-2014 Core-curriculum in renal pathology for residents in pathology