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CV - Caroline E. Fife, M.D. Page 1 of 33 June 2017
CURRICULUM VITAE AND BIBLIOGRAPHY DATE: June 14, 2017 NAME: Caroline E. Fife, M.D., CWS, FUHM PRESENT TITLE: Medical Director
Wound Clinic CHI St. Luke’s Hospital, The Woodlands, Texas Chief Medical Officer Intellicure, Inc. Executive Director, The U.S. Wound Registry
OFFICE ADDRESS: 2700 Research Forest Dr., Suite 10 The Woodlands, TX 77381 Phone: (800) 603-7896
Fax: (832) 550-2941 DATE OF BIRTH: March 10, 1959 CITIZENSHIP: U.S.A. MARITAL STATUS: Married - Alan G. Moore, M.D. UNDERGRADUATE EDUCATION:
1977 – 1982 B.S., Medical Science, Texas A&M University, College Station, Texas (entered Medical School in 1980)
1977 Catalina Marine Science Center Research Diver/Technician
1977 – 1979 Chamber Technician/Research Assistant: Texas A&M University
Hyperbaric Laboratory: Hyperbaric Oxygen Therapy and Experimental Use of Hydrogen/Oxygen Mixtures for Deep Diving
GRADUATE EDUCATION:
1980 – 1984 M.D., Texas A&M University College of Medicine, College Station, Texas (combined BS/MD program)
1980 Elective in Aerospace & Hyperbaric Medicine, Brooks Field School
of Aerospace Medicine, USAF (7/2/80 - 7/16/80)
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POSTGRADUATE TRAINING: 1984 – 1985 Internship: The University of Texas Southwestern Medical
School/St. Paul's Hospital and Parkland Memorial Hospital, Dallas, Texas (6/1/84 - 5/31/85)
1985 – 1987 Residency: Family Medicine, The University of Texas
Southwestern Medical School, St. Paul's Hospital/Parkland Memorial Hospital/Texas Children's Hospital, Dallas, Texas (6/1/85 - 5/31/87)
1986 The Medicine of Diving Academic Course, Directed by Dr.
Jefferson Davis (4/9/86 - 4/12/86)
1987 National Oceanographic and Aerospace Administration/Undersea and Hyperbaric Medical Society: Physicians Hyperbaric Training Program, Key Biscayne, Florida (10/5/87 - 10/23/87)
1988 – 1990 Fellowship: Environmental & Hyperbaric Medicine, Duke
University, F.G. Hall Hypo-Hyperbaric Center, Durham, NC (9/15/88 - 4/5/90)
1989 – 1989 Doppler Bubble Monitoring Tutorial for Kisman-Masurel Coding
System, Defense and Civil Institute of Environmental Medicine (DCIEM), Toronto, Canada (4/19/89 - 4/21/89)
1993 – 1993 Physiologic Training for KC 135 Flight, Johnson Space Center,
NASA (3/9/93 - 3/10/93)
1994 Association of Diving Contractors Commercial Diving Training Seminar, “Introduction to Commercial Diving for Physicians, Denver, Colorado (6/22/94)
1994 Advanced Tutorial, Doppler Detection of Cerebral Emboli, San
Diego, California (2/15/94) EXPERIENCE:
1984 – 1985 Solo practice in Family Medicine, St. Paul's Family Medicine Clinic, Dallas, Texas (3,000 patient practice). (7/15/84 - 8/31/85)
1987 – 1989 Diving Medicine Physician, National Geographic/Institute of
Nautical Archaeology, Texas A&M University, Excavation of the Kas wreck, Turkey. Responsible for 2,000 to 3,500 man/dives per season between 140 and 190 feet. The largest series of open water dives utilizing in water oxygen decompression. (7/15/87 - 9/1/87, 7/15/88 - 9/1/88, 7/15/89 - 9/1/89)
1993 Terrestrial and Zero-G Advanced Life Support Pilot Study: ACLS
Protocols for Space Station Freedom, NASA/JSC, KC 135 Weightlessness Exposures. (4/20/93)
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ACADEMIC APPOINTMENTS:
1988 – 1990 Clinical Instructor, Family Medicine, Duke University/Watts Family Medicine Program. (10/88 - 4/90)
1990 – 1998 Assistant Professor, Anesthesiology, The University of Texas
Medical School at Houston 1991 – 2013 Adjunct Assistant Dental Oncologist and Adjunct Assistant
Professor of Dental Oncology, Division of Surgery and Anesthesiology, Department of Dental Oncology, The University of Texas M.D. Anderson Cancer Center
1995 – 2005 Special Member of Graduate Faculty of The University of Texas
Graduate School of Biomedical Sciences at Galveston 1998 – 2000 Associate Professor, Anesthesiology, The University of Texas
Medical School at Houston
2000 – 2008 Clinical Associate Professor (part-time), Anesthesiology The University of Texas Medical School at Houston
2002 – 2012 Special Consultant, NASA, JSC Neutral Buoyancy Laboratory
2007 – 2008 Associate Professor, Department of Radiology, Baylor College of
Medicine 2008 – 2011 Clinical Associate Professor, Department of Internal Medicine,
Division of Cardiology, The University of Texas Medical School at Houston
2011- 2012 Clinical Professor, Department of Internal Medicine, Division of
Cardiology, The University of Texas Medical School at Houston 2014- present Clinical Professor, Department of Internal Medicine, Division of
Geriatrics, Baylor College of Medicine, Houston, Texas
HOSPITAL APPOINTMENTS:
1990 – 2006 Director, Memorial Hermann Hospital Center for Wound Healing and Hyperbaric Medicine, Hermann Hospital, Houston, TX
1994 – 2000 Director, Memorial Hermann Industrial Medicine, Memorial
Hermann Hospital, Houston, TX
1996 – 2000 Director, Center for Environmental, Aerospace and Industrial Medicine, Memorial Hermann Hospital, Houston, TX
1996 – 1998 Director, Memorial Hermann Hospital Enterostomal Therapy
Nursing 2006 – 2012 Director of Clinical Research, Memorial Hermann Hospital Center
for Wound Healing and Hyperbaric Medicine, Houston, TX
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2012 – present Director, The Wound Care Center, St. Luke’s Hospital, The
Woodlands, Texas LICENSURE:
1985 Texas: G8104
CERTIFICATION:
1988, 1994, 2008 Diplomate, American Academy of Family Practice
1998 Certified in Wound Management, American Academy of Wound Management, Status: Certified Wound Specialist (CWS)
2000, 2010 Subspecialty Board Certified in Undersea and Hyperbaric
Medicine, American Board of Preventative Medicine CURRENT BOARD ACTIVITIES (2014) Alliance of Wound Care Stakeholders: Board of Directors Association for the Advancement of Wound Care (AAWC): Board of Directors American Professional Wound Care Association: Board of Directors PROFESSIONAL ORGANIZATIONS: Local
1990 – 2012 Harris County Medical Society 2012 – present Montgomery County Medical Society
Regional
1987 – 1988 Special Consultant to Texas Medical Association Physician Health Committee (Developed published guidelines for managing physicians with cognitive impairment)
1994 – 1995 Crew Health Care System (CHeCS) Training Consultant
Committee, Space Station Freedom Program, Krug Life Sciences, NASA
2000 Grant Reviewer for John Sealy Memorial Endowment Fund for
Biomedical Research 2000 Reviewer for Office of Naval Research (ONR) 2002 – 2012 Special Consultant to the Neutral Buoyancy Laboratory, NASA
JSC
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2006 – 2012 Special Consultant to Texas Parks and Wildlife Artificial Reefs
Diving Program
National 1984 Alpha Omega Alpha National Honor Society 1989 – Present Undersea and Hyperbaric Medical Society (President Elect 1996, President 1998-2000) 1994 – Present American Medical Association 1995 – Present American College of Hyperbaric Medicine 1995 – 2000 Aerospace Medical Association 1995 – Present International Society of Lymphology
1996 – Present The Wound Healing Society
1998 – Present American Academy of Family Physicians (Diplomate) 1998 – Present American College of Hyperbaric Medicine
1999 American Academy of Family Physicians – Active Teacher in
Family Medicine
2000 – 2005 National Oceanic and Atmospheric Administration (NOAA) Diving Medical Review Board. Five Year Renewable Term
2002 – Present Divers’ Alert Network Medical Advisory Panel (One of 5 physicians available 24 hours a day for advice and
review of difficult cases of decompression sickness) 2003 – 2004 Chairman, FDA Safety Committee for SWHI-01, “A Dose Escalating
Phase 1 Study of GAM501 in the Treatment of Diabetic Ulcers of the Lower Extremity” Selective Genetics Incorporated
2003 – 2006 Board of Directors of the American Academy of Wound
Management (AAWM). 2004 – 2008 Board of Directors, Association for the Advancement of Wound
Care (AAWC) 2014 - Present
2005 Chairman, NASA Safety Engineering Committee: “EVA Camp-Out Prebreathe Protocol Peer Review.” Team Charge: The objective of this consultation was to review the physiological, modeling and operations data related to ISS EVA “Camp-Out” Prebreathe Protocol DCS risk and to assess the appropriateness of the draft JSC flight rule regarding the use of the ISS EVA Camp-Out prebreathe protocol. Final report submitted to NASA/JSC, July, 2005
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2008 Member of the National Quality Forum (NQF) Pressure Ulcer
Framework, tasked by CMS to develop a framework for measuring quality for prevention and management of pressure ulcers at both the facility and practitioner levels across the continuum of healthcare. Funded by AHRQ.
2008 – 2013 Chairman of Data Safety and Monitoring Board: “TURN study:”
NIH trial for Bergstrom, N. (PI), Rapp, M. P. (Co-I), Horn, S (Co-PI). Preventing Pressure Ulcers: A Multi-site RCT in Nursing Facilities. National Institute for Nursing Research and National Institute for Aging.
2009 – Present AAWC National Quality Forum (NQF) representative 2009, 2010 Panel on Wound Care Evidence Based Research (Alliance of
Wound Care Stakeholders) 2010 National Panel: Shifting the Original Paradigm on Pressure Ulcer
Staging (STOP panel, a national organization tasked with redesigning the pressure ulcer staging system).
2016 National Quality Forum Measures Authorization Partnership
Committee for Sub Acute Care.
Undersea & Hyperbaric Medical Society: 1991 – 1994 Executive Committee, Member at Large 1991 – 1996 Chairman: Workshop Committee 1993, 1995 Annual Meeting Program Chairman 1993 – 2000 Member: Publications Committee 1994 – 2000 Member: Multicenter Trials Committee 1996 – 1998 President Elect 1998 – 2000 President 2000 – 2002 Immediate Past President 2009 Chairman: Research Foundation
HONORS AND AWARDS:
1993 Listed in Who’s Who in Diving (issued for the 25th Anniversary of SCUBA Diving)
1994 Alpha Omega Alpha
1996 Arnie Zetterstrom Medal Presented to Scientists who advanced the frontier in the use of hydrogen-oxygen mixtures for deep diving and possesses the character traits of intelligence, curiosity, and dedication exemplified by Arnie Zetterstrom.
1999 AMLI Dia Soren Award for best abstract submitted by an MD
2000 Woman Divers Hall of Fame Inaugural Member
2004 Jefferson C. Davis Clinical Excellence Award, Gulf Coast Chapter,
Undersea and Hyperbaric Medical Society.
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2008 Charles W. Shilling Award: In appreciation for contributions to the
advancement of operational hyperbaric medicine, presented by the Gulf Coast Chapter of the Undersea and Hyperbaric Medical Society
2008 Paul J. Sheffield Award for Teaching Excellence, presented by the
Gulf Coast Chapter of the Undersea and Hyperbaric Medical Society
2009 Roberta S. Abruzzese Publishing Award from Wolters Kluwer
Health for the best publication of the year for the manuscript “Estimating the Applicability of Wound Care Randomized Controlled Trials to General Wound-Care Populations.”
2010 The Robert Schobinger Prize for the best clinical paper, issued at
the 18th International Workshop on Vascular Anomalies,Brussels, Belgium:: Noninvasive characterization of lymphatic architecture and function in control and lymphedema subjects using near-infrared fluorescence imaging: John C. Rasmussen, Ph.D., Milton V. Marshall, Ph.D., I-Chih Tan, Ph.D., Kristen E. Adams, Ph.D., Melissa B. Aldrich, Ph.D., Xuejuan Wang, M.D., Caroline E. Fife, M.D., Erik A. Maus, M.D., Latisha A. Smith, M.D. and Eva M. Sevick-Muraca, Ph.D.
2012 Honorary Fellow Award, American College of Clinical Wound
Specialists 2012 Inducted as a Fellow of the Undersea and Hyperbaric Medical
Society (FUHM) 2013: Sharon Baronowski Founder’s Award: Presented at the Clinical
Symposium for Advances in Skin and Wound Care for advancing the practice of wound care
2013: Eric P. Kindwall, MD Award of Excellence in Clinical Hyperbaric
Medicine EDITORIAL POSITIONS:
2007 – present Clinical Editor: Today’s Wound Center (HMP Communications 2009 – present Editorial Board: Advances in Skin and Wound Care (Wolters
Kluwer Health)
SERVICE ON NATIONAL GRANT REVIEW PANELS, STUDY SECTIONS, COMMITTEES:
1996 – 1997 National Institute of Space Biomedical Sciences Consortium - (Proposal Reviewer)
2011 – 2013 Chairman: NASA Oversight Committee, The 2011 Decompression
Sickness (DCS) Standing Review Panel (SRP) is chartered by the
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Human Research Program (HRP) Program Scientist at the NASA Johnson Space Center (JSC).
SERVICE ON THE UNIVERSITY OF TEXAS MEDICAL SCHOOL AT HOUSTON COMMITTEES:
1996 – 2001 Committee for Protection of Human Subjects, Alternate
1996 – 1997 Member, Red Team Review Committee, National Space Biomedical Research Institute (NASA), UTHSC-H Consortium
1998 – 1999 “Front Desk” Operations Design Team of the Revenue Process
Redesign and IDX Implementation (RPR-IDX) Project 2000- 2005 Customer Service Task Force for University Care Plus SERVICE ON THE UNIVERSITY OF TEXAS MEDICAL SCHOOL AT HOUSTON AFFILIATED HOSPITAL COMMITTEES: Memorial Hermann Hospital
1994 – 1995 Smoking Cessation Committee 1995 – 1996 Skin Integrity Committee 1995 – 2005 Enterostomal Therapy Nursing 1997 – 1998 Hermann Medical Staff Affairs Committee 1997 – 1999 Hermann Volunteer Board of Directors
Wound Center, Lymphedema and Hyperbaric Medicine at Memorial Hermann Hospital
1990 – 2012 Hyperbaric Medicine Center (initiated program) 1991 – 2012 Wound Center/Limb Salvage Center (initiated program) 1995 – 2012 Lymphedema Center (initiated program)
SERVICE ON GRADUATE SCHOOL COMMITTEES:
1994 – 1995 The University of Texas Graduate School of Biomedical Sciences at Galveston
1995 – 1996 Baylor College of Medicine, Department of Audiology, Doctoral
Committee
1997 – 1998 The University of Texas School of Public Health, Masters Thesis Committee
2005 – 2006 The University of Texas School of Nursing, Doctoral Committee
(Mary Pat Rabb) 2006– 2006 Graduate committee of University of New South Wales Australia
(Michael Bennett, MD)
2007 – 2008 Baylor College of Medicine, Masters Thesis Committee (Sharma Ruchi)
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2009 – 2012 The University of Texas Houston Cynthia Davies-Venn Doctoral Committee
SERVICE TO THE COMMUNITY:
Bi-Annual Diving Safety/Medicine Courses for Area Scuba Divers Guest Lecturer on Diving Safety to Area Dive Clubs
Yearly Lay Presentations on Radio and TV on Carbon Monoxide Poisoning
National YMCA Scuba Program Participant
SPONSORSHIP OF STUDENT/GRADUATE/POST DOCTORALRESEARCH/FELLOWSHIPS:
1994 – 1996 Tommy L. Love, D.O. (Fellowship in Hyperbaric Medicine)
1994 Georgeann Baron, Ph.D. (Post Doctoral Research)
1995 David Warmflash (University of Tel Aviv, Sackler School of Medicine, Israel)
1995 Capt. John Allen (Doctoral Project in Audiology)
1995 Cem Buyucakir, M.D. (NATO Research Fellow, Turkish Armed
Forces Medical Corps)
1995 Joseph Dervay, M.D. (The University of Texas Medical Branch, Galveston, Texas, Space Medicine Fellow)
1995 Bernd Schumacher, M.D. (Baylor College of Medicine, Department
of Maternal Fetal Medicine)
1996 Elena Capsuto (The University of Texas School of Public Health, Biometry, Masters Student)
1996 Lubor Jarolimek, M.D. (Orthopedic Resident, The University of
Texas Medical School at Houston)
1996 Brooke Parish, student research (Medical Student, University of Tennessee)
1997 Sean Parks (The University of Texas School of Public Health,
Biometry, Masters Student) 1997 Moshe Kulikovsky, M.D. (Eilat, Israel) Hyperbaric Medicine
Fellowship
1998 Joseph P. Dervey, M.D. (The University of Texas Medical Branch, Galveston, Texas, Master of Medical Science)
1998 Fecundo Caride, D.D.S. (The University of Texas Dental Branch),
Masters, “Histomorphometric Evaluation of the Effect of
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Hyperbaric Oxygen on Wound Healing Following Guided Bone Regeneration: An Experimental Study in Rats”.
1999 Joseph P. Dervay, M.D., M.M.S., FACEP, NASA Flight Surgeon,
fellowship- clinical experience in Hyperbaric Medicine and Wound Care Management.
1999 Erik Maus, M.D. (Mexico City, Mexico), Fellowship in Undersea and
Hyperbaric Medicine
2000 Jaime Aristizabal, M.D. (Colombia) Fellowship in Undersea and Hyperbaric Medicine
2001 Surgeon Commander Jane Risdall, M.D., Royal Navy physician,
Fellowship in Undersea and Hyperbaric Medicine
2002 Gerald Schmitz, M.D. (Costa Rica), Fellowship in Undersea and Hyperbaric Medicine
2003 Jeffrey Ramos, M.D. (Philippines), Fellowship in Undersea and
Hyperbaric Medicine
2004 Odette Valderrama, M.D. (Philippines), Fellowship in Undersea and Hyperbaric Medicine
2005 Alex Suarez-Mendoza, M.D. (Mexico City, Mexico) Fellowship in
Undersea and Hyperbaric Medicine
2005 Charles Cross, Canadian Armed Forces master’s thesis candidate: "Are there significant differences in mainstream Hyperbaric medicine utilization between Canada and the United States?"
2006 Renie Guilliod, M.D. (Venezuela), Fellowship in Undersea and Hyperbaric Medicine
CME PROGRAM DIRECTORSHIPS:
1991 Doppler Monitoring For Scientists (Only course of its kind in the world - attracted scientists from Norway and Germany) Co-Director with Dr. Bruce Butler Sponsor: Undersea and Hyperbaric Medical Society
1992 Strategies for the Stubborn Wound: The Diabetic Foot and Other
Non-Healing Wounds Program Director Sponsors: The University of Texas - Houston Medical School and Hermann Center for Wound Healing
1993 Advances in Hyperbaric Oxygen Therapy
Halifax, Nova Scotia Program Director
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Sponsor: Undersea and Hyperbaric Medical Society 1994 Newly Discovered Mechanisms of Action of Hyperbaric Oxygen
Program Director Sponsor: Undersea and Hyperbaric Medical Society
1998 The Role of Oxygen in Wound Healing
CME Presenter UT-Houston Medical School/Memorial Hospital Southeast Continuing Medical Education Initiative
Sponsor: UT-Houston Medical School and Memorial Hermann Healthcare System
2004 A Primer on Wound Care for the Lymphedema Therapist, Reno
Nevada, National Lymphedema Network Annual Meeting 2006 Wound Healing for the Lymphedema Therapist, Nov.1, 2006,
Nashville, TN 2007 Undersea and Hyperbaric Medicine: Salvage of the Lower
Extremity in the Diabetic with Critical Limb Ischemia, Vascular Considerations, Las Vegas, Nevada
2008 Wound Healing for the Lymphedema Therapist, August 27, 2008,
National Lymphedema Network Annual Meeting 2009 Pressure Ulcers and the Law, Houston Texas, August 23-24, 2008
Meeting Keynotes (incomplete list) 2007 European Conference on “Oxygen & Infection” may 8-9, 2009 &
“5th Karolinska Postgraduate Course in Clinical Hyperbaric Oxygen Therapy” May 7, 2009 at the Clarion Hotel Sign, Stockholm, Sweden
2008 World Union of Wound Healing Societies, Toronto, Canada, June
6, 2008. Adverse Events with Negative Pressure Wound Therapy, data from the US Wound Registry.
2008 Women in Diving, A Perspective After 20 Years. Japanese Society
of Hyperbaric Medicine, Kyushu, Japan, 2008 2010 Does Hyperbaric Oxygen have a Role in Limb Salvage? 9th
Annual Congress of the Chinese Society of Hyperbaric Medicine, Chongqing, China Oct. 22, 2010
2012 Quality Measures and Why We need Them: American
Professional Wound Care Association Keynote Address, Philadelphia, PA
2012 Medicolegal Aspects of Pressure Ulcers, Advanced in Skin and
Wound Care Keynote with Kevin Yankowsky, Orlando, Fl.
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2016 Lymphedema: Extraordinary Challenges: American Professional Wound Care Association Keynote Address
2016 Pressure Injuries: How Deep is Our Understanding?
Thursday, September 8, 2016, Virginia Commonwealth University Annual Meeting.
2016 World Union of Wound Care, Hyperbaric Medicine Section
Director, Florence Italy, September 11, 2016 PAST GRANT SUPPORT National Oceanographic and Atmospheric Administration (#GTP226) Fife CE (PI), Vann
RD, Mebane GY and Dunford RD. Doppler Surveillance of Compressed Air Multi-day Diving. 1989. North Carolina State University College of Humanities and Social Sciences, Social Science Research and Computing Labs. Pollard GW, Mebane GY, Vann RD, Fife CE (Co-PIs), Construction of a Database of Compressed Air SCUBA Diving Between 140 and 180 fsw. 1989. National Oceanographic and Atmospheric Administration. Vann RD, Fife CE (Co-PI), Piantadosi CA. Improving the Efficiency of No-stop Repetitive Nitrox Diving with Surface Interval Oxygen". 1990. National Headache Foundation. Fife CE (PI), Meyer JS. Hyperbaric Oxygen for Migraine Headache, A Randomized, Blinded Trial. 1991–1993. National Headache Foundation. Fife CE (PI), Meyer JS, Hanson S. Transcranial Doppler Evaluation of the Effect of Hyperbaric Oxygen on Vascular Headache. 1992– 1994. R.W. Johnson Pharmaceuticals. Hebert A (PI), Fife CE (Co-PI), A Randomized Blinded Placebo Controlled Trial of E. coli Derived PDGF in the Treatment of Diabetic Foot Ulcerations. 1993–1994. Amgen/Pharmaco. Fife CE (Co-PI), Hebert A, Ericsson C. A Randomized, Blinded, Placebo Controlled Study of Platelet Derived Growth Factors in the Treatment of Venous Stasis Ulcerations. 1993–1994. Progressive Medical Equipment. Fife CE (PI), Barron G. Efficacy of Gradient Calibrated Sequential Compression Pump Therapy for Venous Stasis Ulcers. 1995–1997.
Alpha Therapeutic Corporation. Fife CE (PI), Hebert A, Orlander P, Smalling R, Bradbury W, Lyssy K. A Double-Blind Randomized, Parallel Group Placebo Controlled, Dose Response Study to Evaluate the Safety and Efficacy of Intravenous Lipo PGE1 Therapy in Patients with Ischemic Ulcers Due to Peripheral Vascular Disease. April 1995 – April 1996. (Study terminated by Alpha after preliminary data analysis) Bristol Meyers/Squibb. Hebert A (PI), Fife CE (Co-PI). Multicenter, Double-Blind, Parallel Group Efficacy and Safety Comparison of Ifetroban and Placebo in Patients with Venous Leg Ulcers. June 1995 – June 1996.
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King Pharmaceuticals. Fife CE, Smith L (Co-PIs). A Multi-Center, Double-Blind, Randomized, Parallel, Vehicle And Standard Care-Controlled, Dose-Ranging Study Assessing the Safety and Efficacy of MRE0094 Gel When Applied Topically for 90 Days to Subjects with Diabetic, Neuropathic, Foot Ulcers. 1996. NASA - Johnson Space Center. Fife CE (PI), Dervay J, Powell M, Butler B, Chen P. Effective Lifetime of Gas Micronuclei in Hypobaric Decompression. May 1996 – 1998. CIBA Pharmaceuticals. Fife CE (PI), Brandt K. A Double-Blind, Randomized, Parallel Group, Placebo-Controlled, Multiple-Dose, Multi-Center Trial to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of CGP 46614 in Patients with Chronic Pressure Ulcers Using Daily Topical Application for 16 Weeks with 3-Month Follow-Up Period, Protocol 007. January 1997, study withdrawn. Bedfont Scientific Ltd. Fife CE (PI), Persse D, Wilhelm G, Koch S. The Relationship Between Exhaled Alveolar CO And Blood Carboxyhemoglobin, A Field Trial. March 1997 – 1998. NASA - Johnson Space Center. Butler B, Fife CE (Co-PI), Powell M, Robinson R. Lifetimes of In vivo Gas Bubble Micronuclei. April 1997 – 1999. Organogenesis. Fife CE (PI), Orlander P, McGarvy W. A Multi-Center Prospective Randomized Controlled Trial of Graftskin for the Treatment of Diabetic Foot Ulcers. April 1997 – 1999. NASA - Johnson Space Center. Fife CE (PI), Butler B, Powell, M, Robinson R. Exercise During Prebreathe: Reduction of the Oxygen Prebreathe Time. ($600,000) April 1997 – 1999. Ortec International. Herbert A (PI), Fife CE (Co-PI). A Randomized Feasibility Study to Determine the Appropriate Number and Schedule of Applications of a Collagen Matrix Containing Allograft Cells for the Treatment of Venous Ulcers. May 1999 – December 1999. Novartis. Fife CE (PI). Lower Extremity Ulcer Observational Database Protocol. August 1999. Chrysalis Biotechnology. Fife CE (PI), Orlander P, McGarvy W, Lepow G. Accelerating the Healing of Chronic Diabetic Ulcers: A Pilot Phase II Efficacy Trial Protocol to Evaluate the Effects of the Synthetic Thrombin Peptide Chrysalin. September 1999 – September 2000. American Cancer Society (RSG-06-213-01-LR). Sevick EM (PI), Fife CE (Clinical Collaborator). Quantitative Optical Lymphography in Breast Cancer Patients. ($540,000), July 1, 2006 – June 30, 2009. National Institute for Nursing Research and National Institute for Aging. Fife CE, Consultant and Member, Data Safety and Monitoring Board for: Bergstrom N (PI), Rapp MP (Co-PI), Horn S (Co-PI). Preventing Pressure Ulcers: A Multi-site RCT in Nursing Facilities. ($2,584,626), Priority Score: 126; Percentile: 1.6; July 1, 2007 – June 30, 2011.
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NIH (R01 HL092923-01). Sevick EM (PI), Fife CE (Clinical Collaborator). Functional Lymph Angiography with NIR Imaging. ($1,488,400), September 15, 2008 – June 30, 2012. NIH (R01CA128919). Sevick EM (PI), Fife CE (Clinical Collaborator). Imaging Lymph Function in Humans and in Murine Models of Lymphedema. ($1,556,606), September 16, 2008 – July 31, 2013. Tactile Systems. Sevick EM (PI), Fife CE (Clinical Collaborator). The Use of NIR Optical Imaging to Evaluate the Efficacy of the Flexitouch System. ($89,992), February 28, 2008 – February 28, 2009, ($59,156) October 1, 2009 – October 31, 2015. TAMARIS (HSC-MS-08-0391). Maus E, Smith L, Fife CE. A Randomized Double-blind Placebo-Controlled Parallel Group Study of the Efficacy and Safety of 4 administrations of XRP0038/NV1FGF 4mg at 20-week Intervals on Amputation or Any death in Critical Limb Ischemia Patients with Skin Lesions. ($30,000), under review. TAMARIS (HSC-MS-08-0153). Maus E, Smith L, Fife CE. A Randomized Trial of the Flexitouch Compression System as an Adjunctive Treatment for Venous Stasis Ulcers. ($68,000). NIH (CA161804-01), Fife CE, Sevick EM (PIs). Real Time Imaging to Assess Efficacy of Manual Therapies. October 1, 2011 – September 30, 2016, ($3,525,387), Percentile: 17, resubmission pending.
COMPLETED CLINICAL RESEARCH STUDIES (non-funded):
Fife CE, Meyer JS. “The Effect of Hyperbaric Oxygen (HBO) on Vascular Headache Relief: Randomized Blinded Trial,” CPHS # HSC-MS-90-093, 1991. Fife CE, et al. “Endovasc: A Phase II, Single Center, Non-Placebo Controlled Treatment IND Study of Open Label, Liposomal Prostaglandin E1 (Lipoprostin) as Adjunct Therapy with Percutaneous Transluminal Limb Angioplasty in Patients with Ischemic and Non-Ischemic Peripheral Arterial Occlusive Disease (PAOD),” 1992. Schroth G, Thandroyen F, Fife CE. “Prevalence of Patent Foramen Ovale in Experienced SCUBA Divers,” CPHS # HSC-MS-91-059, 1992. Fife CE, Baron G, Marshall G, Sutton T. “The Effects of Hyperbaric Oxygen Therapy on Cytokine Populations in Wounds,” CPHS # HSC-MS-96-067, 1992. Fife CE, Robinson R, Dother S (Co-investigator). “Carbon Monoxide Exposure during Laproscopic Surgery,” CPHS Administrative Approval, 1992. Fife CE, Butler B. “Transcutaneous Doppler Surveillance of Simulated Compressed Air Dive,” CPHS # HSC-MS-92-045, 1993. University of Texas School of Public Health. Fife CE, Parks S. “Outcome and Cost Analysis of Venous Stasis Ulcerations utilizing Compression Bandaging,” CPHS Administrative Approval, 1993.
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Fife CE, Olson D, Weltge A. “Pilot Study: The Incidence of Occult Carbon Monoxide Poisoning in Emergency Room Patients,” CPHS Administrative Approval,1993. Hebert A, Fife CE. “An Open Label Comparative Study of Hydrocolloid Gel Versus Carrington TM Gel Wound Dressing in the Management of Sloughy Pressure Ulcers,” CPHS # HSC-MS-93-100, 1994. Levenback C, Fife CE. “A Pilot Study of Hyperbaric Oxygen in the Treatment of Pelvic Radiation Toxicity,” CPHS # HSC-MS-91-032, 1994. Fife CE, et al. “Evaluation of Ocular Side Effects in Patients Undergoing Hyperbaric Oxygen Therapy,” CPHS # HSC-MS-91-071, 1995. Fife CE, Capsuto E, Lyssy K, Murphy K, Short C. “Incidence of Pressure Sores in Intensive Care,” CPHS Administrative Approval, 1996. Fife CE, et al. “A Multicenter Analysis of Patient Characteristics, Treatment, Duration and Outcome of Nonhealing Diabetic Wounds Treated with Hyperbaric Oxygen Therapy,” CPHS # HSC-MS-96-031, 1996. Fife CE, Otto G. “Transcutaneous Oximetry at 2.0 vs 2.4 ATA,” CPHS Administrative Approval, 1996. Fife CE, Shumaker B. “Maternal and Fetal Effects of Simulated Airplane Travel,” CPHS # HSC-MS-95-101, 1998. Sevick-Muraca EM, Fife CE. Phase I H-20438, “Imaging Lymph Flow in Normal Controls and Lymphedema Patients,” IND 76,920, February 2007. Sevick-Muraca EM, Fife CE. Phase I, HSC-IMM-08-0401, “Lymphatic Structure and Function in Disease,” Combinational IND 102,765, July 2008, and HSC-IMM-12-290, “NIR Fluroescence Imaging for Assessment of Lymphatics in Cancer Treatment and Recovery,” single patient IND 105,824, August 2012. Sevick-Muraca EM, Fife CE. HSC-IMM-08-0415, “Imaging Lymphatic Function in Normal Subjects and in Persons with Lymphatic Disorders,” Combinational IND 102,827, July 2008.
Ambrose C, Maus E, Smith L, Fife CE. HSC-MS-05-0153, “Identification of Causative Bacteria in Osteomyelitis Using Rapid and Sensitive 16S rRNA Detection and Improved Identification of the Causative Bacteria in Diabetic Ulcer Polymicrobial Infections,” 2009 –2010. Cytomedix. Fife CE. “Platelet Rich plasma in Diabetic Foot Ulcers, Venous Ulcers and Pressure ulcers,” Coverage with Evidence Development Project, 2015.
PATENTS 1. Functional Near-infrared Fluorescence Lymphatic Mapping for Diagnosing
Accessing, Monitoring, and Directing Therapy of Lymphatic Disorders. Sevick-Muraca EM, Fife CE, Marshall MV, Maus EA, Rasmussen JC, Tan IC. 12/886,770, 9/21/2010. (Licensed to NIRF Imaging, 2013)
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PUBLICATIONS: For a complete list of non-peer reviewed publications, see https://carolinefifemd.com/articles Peer-reviewed Articles (open access articles available by hyperlinked title)
1. Fife CE and Fife WP. Treatment of Migraine with Hyperbaric Oxygen. Undersea Hyperbaric Med. 4(1): 7-15, 1989.
2. Smith RB, Gilbert TJ, Fife CE, Fife WP. [Letter] Migraine. J Hyperbaric Med. 4(2): 53,
1989. 3. Butler BD, Robinson BA, Fife CE, Sutton T. Doppler Detection of Decompression
Bubbles with Computer Assisted Digitization of Ultrasonic Signals. Aviat Space Environ Med. 62: 997-1004, 1991.
4. Zhang J, Fife CE, Curry M, Moon RE, Piantadosi CA, Vann RD. Venous Gas
Embolism and Complement Activation after Deep Repetitive Air Diving. Undersea Biomed Res. 18: 293-302, 1991.
5. Vann RD, Fawcett TA, Currie MS, Fife CE, Zhang J, Piantadosi CA. No-Stop
Repetitive N2/02 Diving with Surface Interval 02 (Phase I). Undersea Biomed Res. 19: 79-80, 1992.
6. Pollard GW, Vann RD, Marsh PL, Fife C. The Effects of Ascent Rate and Post-Dive
Exercise on the Development of Decompression Sickness in Rats. Undersea Biomed Res. 19: 34-35, 1992.
7. Akman MN, Loubser PG, Fife CE, Donovan WH. Hyperbaric Oxygen Therapy;
Implications for Spinal Cord Injury Patients with Intrathecal Baclofen Infusion Pumps. Case report. Paraplegia. 32: 281-284, 1994.
8. Okhuysen PC, Rex JH, Kapusta M, Fife CE. Successful Treatment of Extensive
Posttraumatic Soft-Tissue and Renal Infections Due to Apophysomyces elegans. Renal Infectious Diseases. 19: 329-331, 1994.
9. Fife CE, Fife WP. Should Pregnant Women Scuba Dive? A Review of the Literature.
J Travel Med. 1(3): 160-167, 1994. 10. Pracyk JB, Stolp BW, Fife CE, Gray L, Piantadosi CA. Brain Computerized
Tomography After Hyperbaric Oxygen Therapy for Carbon Monoxide Poisoning. Undersea Hyperbaric Med. 22(2): 1-7, 1995.
11. Butler BD, Fife CE, Sutton T, Pogodsky M, Chen P. Hepatic Portal Vein Gas with
Hyperbaric Decompression: Ultrasonic Identification. J Ultrasound Med. 14: 967-970, 1995.
12. Pollard GW, Marsh PL, Fife CE, Smith LR, Vann RD. Ascent Rate, Post-dive
Exercise, and Decompression Sickness in the Rat. Undersea Hyperbaric Med. 22(4): 367-376, 1995.
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13. Schumacher B, Olson G.L. Saade GR, Ou CN, Moise, Jr KJ, Fife CE. Effects of Acute-High-Altitude Exposure and Decreased Atmospheric Pressure on Lactate in Fetal Rabbits. J Soc Gynecol Invest. 3(2S): 275A, 1996.
14. Hanna GP, Fujise K, Kjellgren O, Field S, Fife CE, Schroth G, Clanton T, Anderson
V, Smalling RW. Infrapopliteal Transcatheter Interventions for Limb Salvage in Diabetic Patients: Importance of Aggressive Interventional Approach and Role of Transcutaneous Oximetry. J Am Cardiol. 30: 664-669, 1997.
15. Koch S, Fife CE, Nguyen M, Wilhelm G. Alveolar Carbon Monoxide Compared to
Carboxyhemoglobin in Acute Carbon Monoxide Poisoning. Crit Care Med. 25(1 Suppl), 1997.
16. Robinson R, Swaby G, Sutton T, Fife CE, Powell M, Butler BD. Venturi Vacuum
System for Hypobaric Chamber Operations: Technical Report. Aviat Space Environ Med. 68: 1046-1049, 1997.
17. Schumacher B, Olson G, Saade G, Ou C-N, Sutton T, Moise K, Fife CE. Simulated
Airplane Flight Increases Plasma Lactate in Fetal Rabbits. Undersea Hyperbaric Med. 26(2): 67-73, 1999.
18. Otto GH, Fife CE, Buyukcakir C. Effects of Smoking on Cost and Duration of
Hyperbaric Oxygen Therapy for Diabetic Patients with Non-healing Wounds. Undersea Hyperbaric Med. 27(2): 67-123, 2000.
19. Bozzuto TM, Fife CE. Adjunctive Therapies for Wound Healing. JAMA. 284(1): 40,
2000; author reply 41. 20. Fife CE. Advanced Gestational Age and Fetal Lactate Levels in Flight. Aviat Space
Environ Med. 72(8): 770, 2001. 21. Fife CE, Otto G, Capsuto EG, Brandt K, Lyssy K, Murphy K, Short C. The Incidence
of Pressure Ulcers in a Neurological Intensive Care Unit. Crit Care Med. 29(2): 283-90, 2001.
22. Buchman AL, Fife CE, Torres C, Smith L, Aristizibal J. Hyperbaric Oxygen Therapy
for Severe Ulcerative Colitis. J Clin Gastroenterol. 33(4): 337-339, 2001. 23. Dervay JP, Powell MR, Butler B, Fife CE. The Effect of Exercise and Rest Duration
on the Generation of Venous Gas Bubbles at Altitude. Aviat Space Environ Med. 73(1): 22-7, 2002.
24. Fife CE, Vanderploeg J. ABPM exam: What It's All About. SPUMS J. 32(1):10-11,
2002. 25. Fife CE, Buyukcakir C, Otto GH, Sheffield PJ, Warriner RA, Love TL, Mader J. The
Predictive Value of Transcutaneous Oxygen Tension Measurement in Diabetic Lower Extremity Ulcers Treated with Hyperbaric Oxygen Therapy: a Retrospective Analysis of 1,144 Patients. Wound Rep Regen. 10: 198-207, 2002.
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26. Fife CE, Otto G, Walker D, Turner T, Smith L. Healing Dehisced Surgical Wounds with Negative Pressure Wound Therapy. Ostomy Wound Manage. 50(4A Suppl): 28-31, 2004.
27. Fife CE. Risk vs. Benefit in Hyperbaric Medicine: A Brief Comment. Aviat Space
Environ Med. 75: 995-996, 2004. 28. St Leger Dowse M, Gunby A, Moncad R, Fife CE, Bryason P. A Prospective Field
Study of Reverse Dive Profiles in UK Female Recreational Divers. SPUMS J. 30(4): 183-188, 2004.
29. Feldmeier JJ, Hopf HW, Warriner III RA, Fife CE, Gesell LB, Bennett MH. UHMS
Position Statement: Topical Oxygen for Chronic Wounds. Undersea Hyperb Med. 32(3): 157-68, 2005.
30. Hymes SR, Strom EA, Fife CE. Radiation Dermatitis: Clinical Presentation,
Pathophysiology and Treatment. J Am Acad Dermatol. 54(1): 28-46, 2006. 31. Jennings RT, Murphy DMF, Ware DL, Aunon SM, Moon RE, Bogomolov VV,
Voronkov YI, Fife CE, Boyars MC, Ernst RD. Medical Qualification of a Commercial Spaceflight Participant: Not Your Average Astronaut. Aviat Space Environ Med. 77: 475-484, 2006.
32. St Leger Dowse M, Lee V, Shaw S, Smerdon G, Fife CE, Bryson P. A Relationship
Between the Menstrual Cycle and Decompression Illness. Is the Evidence Building? Eur J Underwater Hyperb Med. 7(4): 84-86, 2006.
33. St Leger Dowse M, Bunby A, Moncad R, Fife CE, Bryson P. Scuba Diving and
Pregnancy: Can We Determine Safe Limits? J Obstet Gynaecol. 26(6): 509-513, 2006.
34. St Leger Dowse M, Gunby A, Oncad RM, Fife CE, Morseman J, Bryson P. Problems
Associated with Scuba Diving Are Not Evenly Distributed Across a Menstrual Cycle. J Obstet Gynaecol. 26(3): 216-221, 2006.
35. Jennings RT, Murphy DM, Ware DL, Aunon SM, Moon RE, Bogomolov VV, Morgun
VV, Voronkov YI, Fife CE, Boyars MC, Ernst RD. Medical Qualifications of a Commercial Spaceflight Participant: Not Your Average Astronaut. Aviat Space Environ Med. 77(5): 475-484, 2006.
36. Hopf, HW, Ueno C, Aslam R, Burnand K, Fife CE, Grant L, Holloway A, Lafrati MD, Mani R, Misare B, Rosen N, Shapshak D, Slade B, West J, Barbul A. Guidelines for the Treatment of Arterial Insufficiency Ulcers. Wound Repair Regen. 14: 693-710, 2006.
37. Fife CE, Walker D, Farrow W, Otto G. Wound Center Facility Billing: A Retrospective
Analysis of Time, Wound Size, and Acuity Scoring for Determining Facility Level of Service. Ostomy Wound Manage. 53(1): 34-44, 2007.
38. Fife CE, Mader J, Stone J, Brill L, Satterfield K, Norfleet A, Zwernemann, A, Ryaby J,
Carney D. Thrombin Peptide Chrysalins Stimulates Healing of Diabetic Foot Ulcers in a Placebo-controlled Phase I/II Study. Wound Repair Regen. 15: 23-34, 2007.
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39. Fife CE, Buyukcakir C, Warriner R, Sheffield P, Love T, Otto G. Factors Influencing
the Outcome of Lower Extremity of Diabetic Ulcers Treated with Hyperbaric Oxygen Therapy. Wound Repair Regen. 15: 322-331, 2007.
40. Fife CE, Walker D, Thomson B, Carter M. Limitations of Daily Living Activities in
Patients with Venous Stasis Ulcers Undergoing Compression Bandaging: Problems with the Concept of Self-bandaging. Wounds. 19(10): 255-257, 2007.
41. Dowse M, Gunby A, Moncad R, Fife CE, Smerdon G, Bryson P. The Combined Oral
Contraceptive Pill and the Assumed 28 Day Cycle. J Obstet Gynecol. 27(5): 481-484, 2007.
42. Fife CE, Walker D, Thomson B, Otto G. The Safety of Negative Pressure Wound
Therapy Using Vacuum-assisted Closure in Diabetic Foot Ulcers Treated in the Outpatient Setting. Int Wound J. 5(Suppl 2): 17-22, 2008.
43. Fife CE, Carter MJ. Lymphedema in the Morbidly Obese Patient: Unique Challenges
in a Unique Population. Ostomy Wound Manage. 54(1): 44-56, 2008.
44. Fife CE, Benavides S, Carter MJ. A Patient-centered Approach to Treatment of Morbid Obesity and Lower Extremity Complications: An Overview and Case Studies. Ostomy Wound Manage. 54(1): 20-2, 24-32, 2008.
45. Rasmussen JC, Tan I-C, Marshall MV, Fife CE, Sevick-Muraca EM. Lymphatic Imaging
in Humans with Near-infrared Fluorescence. Curr Opin Biotechnol. 20(1): 74-82, 2009.
46. Hopf HW, Ueno C, Aslam R, Dardik A, Fife C, Grant L, Holloway A, Iafrati MD, Misare B, Rosen N, Shapshak D, Slade JB Jr, West J, Barbul A. Guidelines for the Prevention of Lower Extremity Arterial Ulcers. Wound Repair Regen. 16(2): 175-188, 2008.
47. Fife CE, Smith LA, Maus EA, McCarthy JJ, Koehler MZ, Hawkins T, Hampson NB.
Dying to Play Video Games: Carbon Monoxide Poisoning from Electrical Generators Following Hurricane Ike. Pediatrics. 123(6): e1035-8, 2009.
48. Hampson N, Dunn S, Bronstein A, Fife CE, Villanacci J, Zane D, et al. Carbon
Monoxide Exposures After Hurricane Ike—Texas, September 2008. MMWR. 58(31): 845-7, 2009.
49. Fife CE, Smart DR, Sheffield PJ, Hopf HW, Hawkins G, Clarke D. Transcutaneous
Oximetry in Clinical Practice: Consensus Statements from an Expert Panel Based on Evidence. Undersea Hyperb Med. 36(1): 43-53, 2009.
50. Ayello EA, Capitulo KL, Fife CE, Fowler E, Krasner DL, Mulder G, Sibbald RG,
Yankowsky KW. Legal Issues in the Care of Pressure Ulcer Patients: Key Concepts for Health Care Providers: A Consensus Paper from the International Expert Wound Care Advisory Panel. Palliat Med. 12: 995-1008, 2009.
51. Carter MJ, Fife CE, Walker D, Thomson B. Estimating the Applicability of Wound-
Care Randomized Controlled Trials to General Wound Care Populations by Estimating the Percentage of Individuals Excluded from a Typical Wound Care Population in Such Trials. Adv Skin Wound Care. 22: 316-24, 2009.
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52. Fife CE, Carter MJ. Lymphoedema in Bariatric Patients. J Lymphoedema. 4(2): 29-
37, 2009. 53. Fife CE, Carter MJ, Walker D, Thomson B. A Retrospective Data Analysis of
Antimicrobial Dressing Usage in 3,084 Patients. Ostomy Wound Manage. 56(3): 28-42, 2010.
54. Fife CE, Carter MJ, Walker D. Why is It So Hard to Do the Right Thing in Wound
Care?" Wound Rep Reg. 18: 154–158, 2010. 55. Fife CE, Maus E A, Carter MJ. Lipedema: A Frequently Misdiagnosed and
Misunderstood Fatty Deposition Syndrome. Adv Skin Wound Care. 23: 81-92, 2010. 56. Marshall MV, Rasmussen JC, Tan IC, Aldrich MB, Adams KE, Wang X, Fife CE,
Maus EA, Smith LA, Sevick-Muraca EM. Near-infrared Fluorescence Imaging in Humans with Indocyanine Green: A Review and Update. Open Surg Oncol J. 2(2): 12-25, 2010.
57. Adams K, Rasmussen JC, Darne C, Tan I-C, Aldrich MB, Marshall MV, Fife CE,
Maus EA, Smith LA, Guilliod R, Hoy S, Sevick-Muraca EM. Direct Evidence of Lymphatic Function Improvement after Advanced Pneumatic Compression Device Treatment of Lymphedema. Biomed Opt Express. 1(1): 114-125, 2010.
58. Fife CE, Yankowsky KW, Ayello EA, Capitulo KL, Fowler E, Krasner DL, Mulder G, Sibbald RG. Legal Issues in the Care of Pressure Ulcer Patients: Key Concepts for Health Care Providers--A Consensus Paper from the International Expert Wound Care Advisory Panel©. Adv Skin Wound Care. 23(11): 493-507, 2010.
59. Rasmussen JC, I-Chih T, Marshall MV, Adams KE, Kwon S, Fife CE, Maus EA,
Smith LA, Covington KR, Sevick-Muraca EA. Human Lymphatic Architecture and Dynamic Transport Imaged Using Near-infrared Fluorescence. Transl Oncol. 3(6): 362-372, 2010.
60. Fife CE, Hopf H. Commentary: A Review of the Mechanisms of Hyperbaric Oxygen
Therapy After 50 Years. Plast Reconstr Surg. 127(Suppl): 131S, 2011. 61. Fife CE, Hopf H. Discussion. Hyperbaric Oxygen: Its Mechanisms and Efficacy. Plast
Reconstr Surg. 127 Suppl 1: 142S-143S, 2011. 62. Tan IC, Maus EA, Rasmussen JC, Marshall MV, Adams KE, Fife CE, Smith LA,
Chan W, Sevick-Muraca EM. Assessment of Lymphatic Contractile Function after Manual Lymphatic Drainage Using Near-infrared Fluorescence Imaging. Arch Phys Med Rehabil. 92(5): 756-764 e1, 2011.
63. Fife C, St Leger Dowse M. Women and Pressure. Diving Hyperb Med. 41(1): 39;
author reply 39, discussion 39, 2011. 64. Snyder RJ, Driver V, Fife CE, Lantis J, Peirce B, Serena T, Weir D. Using a
Diagnostic Tool to Identify Elevated Protease Activity Levels in Chronic and Stalled Wounds: A Consensus Panel Discussion. Ostomy Wound Manage. 57(12): 36–46, 2011.
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65. Maus EA, Tan IC, Rasmussen JC, Marshall MV, Fife CE, Smith LA, Guilliod R,
Sevick-Muraca EM. Near-infrared Fluorescence Imaging of Lymphatics in Head and Neck Lymphedema. Head Neck. 34(3): 448-453, 2012.
66. Fife, CE, Carter MJ, Walker D, Thomson B. Wound Care Outcomes and Associated
Cost Among Patients Treated in U.S. Outpatient Wound Centers: Data from the U.S. Wound Registry. Wounds. 24(1): 10-17, 2012.
67. Fife, CE, Wall V, Carter M, Walker D, Thomson B. Examining the Relationship
Between Physician and Facility Level-of-Service Coding in Outpatient Wound Centers: Results of a Multicenter Study. Ostomy Wound Manage. 58(3): 20-28, 2012.
68. Fife CE, Yankowsky K, Carter MJ. Do Pressure Ulcer Prevention Protocols Improve
Patient Care But Increase Institutional Risk? Ostomy Wound Manage. 58(11): 48-7, 2012.
69. Aldrich MB, Guilliod R, Adams KE, Darne C, Fife CE, Maus EA, Smith L, Marshall
MV, Rasmussen JC, Tan IC, Wang X, Sevick-Muraca EM. Lymphatic Abnormalities in the Normal Contralateral Arms of Subjects with Breast Cancer-related Lymphedema as Assessed by Near-infrared Fluorescence Imaging. Biomed Opt Express. 3(6): 1256-1265, 2012.
70. Serena T, Bates-Jensen B, Carter MJ, Cordrey R, Driver V, Fife CE, Haser PB,
Krasner D, Nusgart M, Smith AP, Snyder RJ. Consensus Principles for Wound Care Research Obtained Using a Delphi Process. Wound Repair Regen. 20(3): 284-293, 2012.
71. Fife CE, Davey S, Maus EA, Guilliod R, Mayrovitz HN. A Randomized Controlled
Trial Comparing Two Types of Pneumatic Compression for Breast Cancer-related Lymphedema Treatment in the Home. Support Care Cancer. 20(12): 3279-3286, 2012.
72. Fife CE, Wall V, Carter MJ, Walker D, Thomson B, Turner T. Revenue in U.S.
Hospital Based Outpatient Wound Centers: Implications for Creating Accountable Care Organizations. J Hosp Admin. 2013; 2(3): 38-45.
73. Fife CE, Carey D, Spong K, Strba B, Wall V. Remote Medical Quality Management:
Improving Physician Practice Standards in Wound Care Via Telemedicine. J Wound Technol. 20: 46–50, 2013.
74. Horn SD, Fife CE, Smout RJ, Barrett RS, Thomson B. Development of a Wound
Healing Index for Patients with Chronic Wounds. Wound Rep Reg. 21; 823-832, 2013.
75. Fife CE, Walker D, Thomson B. Electronic Health Records, Registries, and Quality
Measures: What? Why? How? Adv Wound Care. 2(10): 598-604, 2013. 76. Burrows PE, Gonzalez-Garay ML, Rasmussen JC, Aldrich ME, Guilliod R, Maus EA,
Fife CE, Kwon S, Lapinski PE, King PD, Sevick-Muraca EM. Lymphatic Abnormalities Are Associated with RASA1 Mutations in Mouse and Man. Proct Natl Acad Sci. 110(21): 8621-8626, 2013.
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77. Carter MJ, Fife CE, Bennett M. Comment on: Margolis et al. Lack of Effectiveness of
Hyperbaric Oxygen Therapy for the Treatment of Diabetic Foot Ulcer and the Prevention of Amputation: A Cohort Study. Diabetes Care. 36: 1961-1966, 2013.
78. Linden R, Ledez K, Hopf H, Fife C. Topical Oxygen Therapy Is Not Hyperbaric
Therapy and the Two Treatments Should Not Be Confused. Int Wound J. 11(2): 230-231, 2014.
79. Rasmussen JC, Herbst KL, Aldrich MB, Darne CD, Tan IC, Zhu B, Guilliod R, Fife
CE, Maus EA, Sevick-Muraca EM. An Abnormal Lymphatic Phenotype is Associated with Subcutaneous Adipose Tissue Deposits in Dercum's Disease. Obesity. 22(10): 2186-2192, 2014.
80. Agollah GD, Gonzalez-Garay ML, Rasmussen JC, Tan I-C, Aldrich M.B, Darne C,
Fife CE, Guilloid R, Maus EA, King PD, Sevick-Muraca EM. Evidence for SH2 Domain-containing 5'-inosotil Phosphatase-2 (SHIP2) Contributing to a Lymphatic Dysfunction. PLoS One. 9(11): e112548, 2014.
81. Fife CE, Carter MJ, Walker D, Thomson B, Eckert KA. Diabetic Foot Ulcer Off-
loading: The Gap between Evidence and Practice. Data from the US Wound Registry. Adv Skin Wound Care 27(7): 310-316, 2014.
82. Fife CE. Massive Localized Lymphedema, a Disease Unique to the Morbidly Obese:
A Case Study. Ostomy Wound Manage. 60(1): 30-35, 2014. 83. Fife CE, Schaum KD. Now Available: Wound Care-Related Quality Measures. Adv
Skin Wound Care. 27(9): 391-395, 2014. 84. Snyder RJ, Frykberg RG, Rogers LC, Applewhite AJ, Bell D, Bohn G, Fife CE,
Jensen J, Wilcox J. The Management of Diabetic Foot Ulcers Through Optimal Off-loading: Building Consensus Guidelines and Practical Recommendations to Improve Outcomes. J Am Podiatr Med Assoc. 104(6): 555-67, 2014.
85. Horn S, Fife CE, Barret R, Thomson B. A Predictive Model for Pressure Ulcer
Outcome: The Wound Healing Index. Adv Skin Wound Care. 28(12): 560-572, 2015. 86. Rasmussen JC, Aldrich MB, Guilliod R, Fife CE, O’Donnell TF, Sevick-Muraca EM.
Near-infrared Fluorescence Lymphatic Imaging in a Patient Treated for Venous Occlusion. Journal of Vascular Surgery Cases. 1(3): 201-204, 2015.
87. Rasmussen JC, Fife CE, Sevick-Muraca EM. Near-infrared Fluorescence Lymphatic
Imaging in Lymphangiomatosis. Lymphat Res Biol. 13(3): 195-201, 2015. 88. Gould L, Abadir P, Brem H, Carter M, Conner-Kerr T, Davidson J, DiPietro L, Falanga
V, Fife C, Gardner S, Grice E, Harmon J, Hazzard WR, High KP, Houghton P, Jacobson N, Kirsner RS, Kovacs EJ, Margolis D, McFarland Horne F, Reed MJ, Sullivan DH, Thom S, Tomic-Canic M, Walston J, Whitney JA, Williams J, Zieman S, Schmader K. Chronic Wound Repair and Healing in Older Adults: Current Status and Future Research. Wound Repair Regen. 23(1): 1-13, 2015.
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89. Gould L, Abadir P, Brem H, Carter M, Conner-Kerr T, Davidson J, DiPietro L, Falanga V, Fife C, Gardner S, Grice E, Harmon J, Hazzard WR, High KP, Houghton P, Jacobson N, Kirsner RS, Kovacs EJ, Margolis D, McFarland Horne F, Reed MJ, Sullivan DH, Thom S, Tomic-Canic M, Walston J, Whitney JA, Williams J, Zieman S, Schmader K. Chronic Wound Repair and Healing in Older Adults: Current Status and Future Research. J Am Geriatr Soc. 63(3): 427-438, 2015.
90. Fife CE, Eckert KA, Carter MJ. An Update on the Appropriate Role for Hyperbaric
Oxygen: Indications and Evidence. Plast Reconstr Surg. 138(3 Suppl): 107S-116S, 2016.
91. Fife CE, Gelly H, Walker D, Eckert KA. Rapid Analysis of Hyperbaric Oxygen
Therapy Registry Data for Reimbursement Purposes: Technical Communication. Undersea Hyperb Med. 43(6):627-634, 2016.
92. Carter MJ, Gilligan AM, Waycaster CR, Fife CE. Treating Pressure Ulcers with
Clostridial Collagenase Ointment: Results from the US Wound Registry. Wound Repair Regen. 24(5): 904-912, 2016.
93. Rasmussen JC, Aldrich MB, Guilloid R, Fife CE, O’Donnell TF, Sevick-Muraca EM.
Near-infrared Fluorescence Lymphatic Imaging in a Patient Treated for Venous Occlusion. J Vasc Surg Cases. 4(1): 9-17, 2016.
94. Rasmussen JC, Aldrich MB, Tan IC, Darne C, Zhu B, O’Donnell TF, Fife CE, Sevick-
Muraca EM. Lymphatic Transport in Patients with Chronic Venous Insufficiency and Venous Leg Ulcers Following Sequential Pneumatic Compression. J Vasc Surg Venous Lymphat Disord. 4(1): 9-17, 2016.
95. Fife CE, Horn Susan D, Smout RJ, Barrett RS, Thomson B. A Predictive Model for
Diabetic Foot Ulcer Outcome: The Wound Healing Index. Adv Wound Care. 5(7): 279-287, 2016.
96. Snyder RJ, Fife CE, Moore Z. Components and Quality Measures of DIME
(Devitalized Tissue, Infection/Inflammation, Moisture Balance, and Edge Preparation) in Wound Care. Adv Skin Wound Care. 29(5): 205-215, 2016/
97. Carter MJ, Gilligan AM, Waycaster CR, Schaum K, Fife CE. Cost Effectiveness of Adding Clostridial Collagenase Ointment to Selective Debridement in Individuals with Stage IV Pressure Ulcers. J Med Econ. 20(3): 253-265, 2017.
98. Carter MJ, Fife CE. Clinic Visit Frequency in Wound Care Matters: Data from the US
Wound Registry. J Wound Care. 26(Sup1): S4-S10, 2017.
99. Gilligan AM, Waycaster CR, Bizier R, Chu BC, Carter MJ, Fife CE. Comparative Effectiveness of Clostridial Collagenase Ointment to Medicinal Honey for Treatment of Pressure Ulcers. Adv Wound Care (New Rochelle). 6(4): 125-134, 2017.
100. Fife CE, Eckert KA. Harnessing Electronic Healthcare Data for Wound Care
Research: Standards for Reporting Observational Registry Data Obtained Directly from Electronic Health Records. Wound Repair Regen. 2017 Apr 1. doi: 10.1111/wrr.12523. [Epub ahead of print]
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101. Serena TE, Fife CE, Eckert KA, Yaakov RA, Carter MJ. A New Approach to Clinical Research: Integrating Clinical Care, Quality Reporting, and Research Using a Wound Care Network-based Learning Healthcare System. Wound Repair Regen. 2017 Apr 17. doi: 10.1111/wrr.12538. [Epub ahead of print]
102. Fife CE, Farrow W, Hebert AA, Armer NC, Stewart BR, Cormier JN, Armer JM: Skin
and Wound Care in Lymphedema Patients; A Taxonomy, Primer and Literature Review. Adv Skin Wound Care. 2017 (30) 1-14.
Books
1. Wound Care Practice, 1st Edition. Eds: Sheffield PS, Smith APS, Fife CE. Best
Publishing, 2004.
2. Wound Care Practice, 2nd Edition. Eds: Sheffield PS, Fife CE. Best Publishing, 2009.
3. Women and Pressure: Diving and Altitude. Eds: Fife CE, St. Leger Dowse M. Best Publishing 2010.
4. Women and Pressure: Diving and Flying Special Edition. Eds: Fife CE, St. Leger
Dowse M. Best Publishing, 2011.
5. The Wound Care Certification Study Guide. Eds: Shah J, Sheffield P, Fife CE. Best Publishing, 2011.
Book Chapters
1. Fife CE, Camporesi EM. Physiologic Effects of Hyperbaric Hyperoxia. In: Problems
in Respiratory Care, Clinical Applications of Hyperbaric Oxygen, Eds: Camporesi EM, Moon RE. J.B. Lippincott Co: Philadelphia, 4(2): 142-149, 1991.
2. Fife CE, Piantadosi CA. Oxygen Toxicity. In: Problems in Respiratory Care, Clinical Applications of Hyperbaric Oxygen. Eds: Camporesi EM, Moon RE. J.B. Lippincott Co, Philadelphia, 4(2): 150-171, 1991.
3. Fife CE. Hyperbaric and Diving Medicine. In: Anesthesiology, A Comprehensive
Study Guide. Ed: Katz J. McGraw-Hill, 70-76, 1996. 4. Fife CE. In: Preferred Practice Protocols for Hyperbaric Medicine. Ed: Kelly Hill R.
American College of Hyperbaric Medicine, 1998. 5. Fife CE. Hyperbaric Oxygen in the Treatment of Headache. In: Textbook of
Hyperbaric Medicine, Third Edition. Ed: Jain KK. Hogrefe and Huber, 2000.
6. Fife CE. Hyperbaric Oxygen Therapy Applications in Wound Care. In: Wound Care Practice, 1st edition. Eds: Sheffield PS, Smith APS, Fife CE. Best Publishing, 661-684, 2004.
7. Smith APS, Fife CE. Advanced Therapeutics: The Biochemistry and Biophysical
Basis of Wound Products. In: Wound Care Practice, 1st edition. Eds: Sheffield PS, Smith APS, Fife CE. Best Publishing, 685-730, 2004.
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8. Fife CE. Hyperbaric Oxygen Therapy. In: Wound Healing: Science and Practice.
Eds. Falabella, Kirsner. Taylor Publishing, 2005. 9. Chambers MS, Martin JW, Fife CE, Garden AS, Gerngross PJ, Werning JW,
Mendenhall W. Osteoradionecrosis. In: Oral Cancer: Diagnosis, Management and Rehabilitation. 1st ed. Ed: Werning JW. New York, NY: Thieme Medical Publishers, Inc., 296-303, 2007.
10. Fife CE. Lymphedema the Hidden Epidemic. In: Geriatric Dermatology. Ed: Norman
RA. 2006.
11. Fife CE. Lymphedema, an Epidemic Hidden in Plain Sight. In: Wound Care Practice, 2nd edition. Eds: Sheffield PJ, Fife CE. Best Publishing, 377-404, 2007.
12. Fife CE, Warriner RA. Hyperbaric Oxygen Therapy. In: Wound Care Practice, 2nd
edition. Eds: Sheffield PJ, Fife CE. Best Publishing, 947-980, 2007.
13. Fife CE. Pressure Sores: Towards a New Understanding of an Old Problem. In: Wound Care Practice, 2nd edition. Eds: Sheffield PJ, Fife CE. Best Publishing, 431-466, 2007.
14. Fife CE. Hyperbaric Oxygen Therapy in Headache. In: The Textbook of Hyperbaric
Medicine, 4th Ed. Ed: Jain KK. Hogrefe and Huber, 2008. 15. Fife CE, Fife WP. Hyperbaric Oxygen Therapy in Chronic Lyme Disease. In: The
Textbook of Hyperbaric Medicine, 4th Ed. Ed: Jain KK. Hogrefe and Huber, 150-155, 2008.
16. Carter MJ, Fife CE. Factors Affecting the Healing of Chronic Wounds: An
Iconoclastic View. In: Microbiology of Wounds. Eds: Percival S, Cutting K. CRC Press of Taylor & Francis, 2010.
17. Pulak C, Vann RD, Fife CE. Underwater Archeology. In: Women and Pressure:
Diving and Flying, Special Edition. Eds: Fife CE, St. Leger Dowse M. Best Publishing, 295-299, 2011.
18. Fife CE. Pathophysiology of Wound Healing. In: The Wound Care Certification Study
Guide. Eds: Shah J, Sheffield P, Fife CE. Best Publishing, 33-38, 2011.
19. Fife CE, Shah J. Wound Assessment. In: The Wound Care Certification Study Guide. Eds: Shah J, Sheffield P, Fife CE. Best Publishing, 49-62, 2011.
20. Fife CE, Shah J. Wound Bed Preparation and Advanced Technologies for Wound
Healing. In: The Wound Care Certification Study Guide. Eds: Shah J, Sheffield P, Fife CE. Best Publishing, 97-110, 2011.
21. Simman R, Fife CE. Managing the Wound Patient: Surgery, Debridement, Grafts and
Flaps. In: The Wound Care Certification Study Guide. Eds: Shah J, Sheffield P, Fife CE. Best Publishing, 191-200, 2011.
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22. Fife CE. Highlights of National Treatment Guidelines and Quality Reporting in Wound Care. In: The Wound Care Certification Study Guide. Eds: Shah J, Sheffield P, Fife CE. Best Publishing, 271-280, 2011.
23. Fife CE, Carter MJ. Lipolymphedema. In: Color Atlas and Synopsis of Vascular
Disease. Eds: Dean S, Satiani B. McGraw-Hill Education, 2014.
24. Fife CE. Lymphedema. In: Wound Care Essentials: Practice Principles. Eds: Baranowski S, Ayello EA, Lippincott Williams & Wilkins, 358-376, 2015.
25. Krasner, D, Yankowsky K, Fife CE. Regulatory and Legal Issues in Wound Care. In:
Chronic Wound Care 5th Edition; A Clinical Source Book for Health Care Professionals. Eds: Krasner, Sibbald, Woo. HMP Communications, in press.
26. Fife CE, Eckert KA. Hyperbaric Oxygen Therapy and Chronic Lyme Disease: The
Controversy and the Evidence of Treating an Off-label Condition that May or May not Exist. In: Textbook of Hyperbaric Medicine. 6th ed. Ed: Jain KK. Springer, New York, 171-181, 2016.
27. Fife CE, Eckert KA, Workman WT. Ethical issues, Standards, and Quality Control in
Practice of Hyperbaric Medicine. In: Textbook of Hyperbaric Medicine. 6th ed. Ed: Jain KK. Springer, New York, 597-608, 2016.
Proceedings and Contributions 1. Fife CE. Repetitive Multi-day Air SCUBA Diving between 140 and 170 fsw: Update on
an Ongoing Project. In: Proceedings of the 10th Meeting of United States/Japanese Research Program in Natural Resources. Panel on Diving Physiology and Technology. 1989.
2. Fife CE. Multiday Repetitive Deep Air Diving: A Report on the Kas Excavation.
Proceedings of the 20th Annual Meeting of the European Undersea and Baromedical Society, Istanbul, Turkey, September, 1994.
3. Tan IC, Maus EA, Rasmussen JC, Marshall MV, Fife CE, Smith LA, Sevick-Muraca EM. Near-infrared Fluorescence Imaging of Lymphatics in Head and Neck Lymphedema. Proceeding of SPIE Photonic West, Advanced Biomedical and Clinical Diagnostic Systems IX, Mahadeva-Jansen, Vo-Dink, Grundfest, Volume 7890, 2011.
4. Rasmussen JC, Bautista M, Dickinson G, Niccum B, Tan IC, Adams KE, Aldrich MB, Marshall MV, Fife CE, Maus EA, Smith LA. Zhou K, Sevick-Muraca EM. Validation of AutoLF, a Platform for Quantifying Near-infrared Fluorescent Images of Lymphatic Propulston in Humans. Proceedings of SPIE, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IX, editors DL Farkas, DV Nicolau, RC Lief, Volume 7902, 2011.
Web-Based Publications
1. Fife CE, Smith L, Aristizabal J, Parker K. Clinical Use of Semi-Synthetic Human Skin for Wound Healing. http://www.cyberounds.com, 1999.
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2. Fife CE. Management of Peripheral Vascular Disease: The Non-Healing Foot Ulcer A Practical Approach to Assessment and Treatment. http://www.cyberounds.com, 1999.
3. Fife CE. Advances in Wound Treatment of The Diabetic Foot. Update on Foot and
Ankle, Audio-Digest Orthopaedics 23:02. Audio-Digest Foundation. http://www.audiodigest.org , February 2000.
4. Nates J, Aristizabal J, Kim D, Fife CE. Venous Air Embolism during Supine
Craniotomy for Aneurysm: Role of Hyperbaric Oxygen. The Internet Journal of Anesthesiology, ISSN 1092-406X, Vol4N3. http://www.ispub.com, August 2000.
5. Fife CE, Otto GH, Koch S, Nguyen M, Wilhelm G. A Noninvasive Method for Rapid
diagnosis of Carbon Monoxide Poisoning. The Internet Journal of Emergency & Intensive Care Medicine, ISSN 1092-4051, http://www.ispub.com, September 2001.
6. International Best Practice Statement: Optimising patient involvement in wound management. Wounds International. www.woundsinternational.com, 2015.
OTHER PROFESSIONAL COMMUNICATIONS: Selected Invited Presentations
1. *Keynote Address: The Pioneering Contributions of San Antonio and the Air Force to the Modern Practice of Hyperbaric Medicine and Wound Care. Symposium on Advanced Wound Care Annual Meeting, San Antonio, TX, April 30, 2006.
2. *Invited Chair: Sharing Best Practices in the Transition of Patients with V.A.C.®
Therapy from Hospital Care to the Home Care Setting. 21st Century Wound Care Putting the Patient First, Lisbon, Portugal, May 14, 2008.
3. *Invited Lecture: Safety of Negative Pressure. World Union of Wound Healing
Societies, Toronto, Canada, June 5, 2008.
4. *Invited Lecture: Managing Lymphedema in the Morbidly Obese. World Union of Wound Healing Societies, Toronto, Canada, June 5, 2008.
5. Invited Lecture: The Safety of Negative Pressure in Outpatients. Istanbul University,
Istanbul, Turkey, July 9, 2008.
6. *Keynote Address: The History of Wound Care. Undersea and Hyperbaric Medical Society Physician Board Review Course, Undersea and Hyperbaric Medical Society Gulf Coast Chapter meeting, Marriott Waterway, Woodlands TX, August 7, 2008.
7. *CME director: Wound Care for the Lymphedema Therapist Course. National
Lymphedema Network, San Diego, CA, August 29, 2008. 8. *CME course director: Pressure Ulcers and the Law. The Houstonian, Houston, TX,
September 23-24, 2008. 9. *Invited Lecture: Women in Diving, A Perspective After 20 Years. U.S. Japanese
Hyperbaric Society Meeting; Kyushu, Japan, November 7, 2008.
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10. *Invited Speaker: Hyperbaric Oxygen Therapy and the Diabetic Foot Ulcer and
Evidence Based Interpretation of Transcutaneous Oximetry. Oxygen and Infection Conference, endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), European Committee for Hyperbaric Medicine (ECHM); Stockholm, Sweden, May 7-8, 2009.
11. *Keynote Address: Transcutaneous Oximetry in Limb Salvage. Israeli Hyperbaric
Oxygen Society Meeting, Assaf Harofeh Hospital, Tel Aviv, Israel, September 24, 2009.
12. Negative Pressure Wound Therapy, an Economic Analysis. Vancouver, BC,
September 29, 2009. *Indicates international lectures, keynote addresses, and continuing medical education (CME)
Directorships
Other International Presentations, Published Abstracts, and Awarded Presentations 1. Fife CE, Gray L, Salee S, Piantadosi CA. The Prognostic Value of Brain CT
Following HBO in Severely Poisoned CO Patients. Undersea and Hyperbaric Medical Society Annual Scientific Meeting, June 6-11, 1989. Undersea Biomed. Res, 16(S):19, 1989.
2. Fife CE, Vann RD, Mebane GY, Dunford RD. Doppler Surveillance of Open-Water
Multi-Day Repetitive Diving. Undersea and Hyperbaric Medical Society Joint Meeting on Diving and Hyperbaric Medicine, August 11-18, 1990. Undersea Biomed Res. 17(S):135-136, 1990.
3. Fife CE, Zhang J, Vann RD, Currie MS, Moon RE, Piantadosi CA. Decompression
Stress After Repetitive Deep Air Dives: Use of Doppler Monitoring and Complement Activation. Undersea and Hyperbaric Medical Society Joint Meeting on Diving and Hyperbaric Medicine, August 11-18, 1990. Undersea Biomed Res. 17(S):104-105,1990.
4. Fife CE, Pollard GW, Mebane GY, Vann RD, Boso AE. A Database of Open-Water,
Compressed Air, Multi-Day Repetitive Dives to Depths of 100-190 FSW. Undersea and Hyperbaric Medical Society Annual Scientific Meeting, June 19-23, 1991. Undersea Biomed Res. 18(S):51, 1991.
5. Butler BD, Fife CE. Decompression Bubbles and Doppler: Enhancement of Bubble
Grade Analysis with Digitized Signals. Undersea and Hyperbaric Medical Society Annual Scientific Meeting, June 19-23, 1991. Undersea Biomed Res. 18(S):65, 1991.
6. Fife CE, Meyer JS, Berry JM, Sutton TE. Hyperbaric Oxygen and Acute Migraine
Pain: Preliminary Results of a Randomized, Blinded Trial. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, June 23-27, 1992. Undersea Biomed Res. 19(S)178:106-107, 1992.
7. Pollard GW, Vann RD, Marsh PL, Fife CE. The Effects of Ascent Rate and Post-Dive
Exercise on the Development of Decompression Sickness in Rats. Undersea and Hyperbaric Medical Society Annual Scientific Meeting, June 23-27, 1992. Undersea Biomed Res. 19(S)36:34-35, 1992.
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8. Sutton T, Swaby G, Benavidez E, Berry J, Fife CE. Alternative Breathing Gas
Delivery System for Tracheostomy Patients in the Multiplace Hyperbaric Chamber. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, June 23-27, 1992. Undersea Biomed Res. 19(S)88:61-62, 1992.
9. Vann RD, Fawcett TA, Currie MS, Fife CE, Zhang J, Piantadosi CA. No-Stop
Repetitive N2/O2 Diving with Surface Interval O2 (SIO2): Phase I. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, June 23-27, 1992. Undersea Biomed Res. 19(S)125:79-80,1992.
10. Fife CE, Hanson S, Mever JS, Maklad N. Transcranial Doppler Evaluation of
Cerebral Vessels during Hyperbaric Oxygenation. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, July 7-10, 1993. Undersea Hyperbaric Med. 20(S)5: 14, 1993.
11. Fife CE, Thandroyen F, Toole T, Schroth G, Dunford RD, Laasko B, Sutton T.
Echocardiographic and Audible Doppler Surveillance of Venous Gas Emboli in Compressed Air Divers. Undersea and Hyperbaric Medical Society Annual, Scientific Meeting, July 7-10, 1993. Undersea Hyperbaric Med. 20(S)125:79, 1993.
12. Aguilar III EA, Smith K, Fife CE. Salvage of Auricular Reconstruction Using
Hyperbaric Therapy. Proceedings: American Academy of Facial Plastic and Reconstructive Surgery, September 30, p 23, 1993.
13. Butler BD, Larson SR, Sutton T, Fife CE, Koch S. Emergency Intubation in a
Hyperbaric Chamber: Verification of Endotracheal Tube Placement Using a Disposable CO2 Detector. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, July 7-10, 1993. Undersea Hyperbaric Med. 20(S)34: 29-30, 1993.
14. Thandroyen FT, Fife CE, Schroth G. Right to Left Atrial Shunting and Right Heart
Pressure in Asymptomatic, Experienced Divers. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, July 7-10, 1993. Undersea Hyperbaric Med. 20(S)129: 81-82, 1993.
15. Fife CE, Powell MG, Sutton TE, Meyer JS. Transcranial Doppler Evaluation of the
Middle Cerebral Artery From 1 ATA to 3 ATA PO2. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, June 22-26, 1994. Undersea Hyperbaric Med. 21(S)117:77, 1994.
16. Sutton T, Swaby G, Saur S, Powell M, Butler BD, Fife CE. Adaptation of a
Hyperbaric Oxygen Therapy Chamber for Human Hypobaric Studies. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, June 22-26, 1994. Undersea Hyperbaric Med. 21(S)59:45, 1994.
17. Swaby GH, Hildreth S, McKinley BA, Fife CE. Preliminary Hyperbaric Test of Ivac
Med System III Fluid Infusion System. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, June 22-26, 1994. Undersea Hyperbaric Med. 21(S)58:44-45, 1994.
18. Sutton T, Freese M, Saur S, Swaby G, Fife CE, Berry J. Testing of a Portable Blood
Gas Analyzer Under Hyper/Hypobaric Conditions. Undersea and Hyperbaric Medical
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Society, Annual Scientific Meeting, June 22-26, 1994, Undersea Hyperbaric Med. 21(S)69:50, 1994.
19. Love T, Fife CE, Sutton T, Benoit D, Butler BD. Arterial Gas Embolism Following
Decompression with No Evidence of a Patent Foramen Ovale. (Poster Presentation) Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, June 20-24, 1995. Undersea Hyperbaric Med. 22(S)91:59, 1995.
20. Butler BD, Fife CE, Sutton T, Pogodsky M, Chen P. Portal Vein Gas After
Decompression: Case Report. (Poster presentation) Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, June 20-24, 1995. Undersea Hyperbaric Med. 22(S)95:61, 1995.
21. Baron GC, Suttle K, Berkowicz L, Love T, Sutton T, Swaby G, Cetina S, Parker K,
Lyssy K, Gold S, Fife CE: Pilot Study of Cytokines Recovered from Non-Healing Lower Extremity Wounds Treated with Adjunctive Hyperbaric Oxygen Therapy. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, Anchorage, Alaska, April 30-May 5, 1996. Undersea Hyperbaric Med. 23(S)65:45, 1996.
22. Büyükcakir C, Otto G, Fife CE. Predictive Factors in Outcome Utilizing Hyperbaric
Oxygen Therapy for Diabetic Nonhealing Wounds. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, Anchorage, Alaska, April 30-May 5, 1996. Undersea Hyperbaric Med. 23(S)76:51-52, 1996.
23. Schumacher B, Olson GL, Saade GR, Ou C-N, Sutton TE, Moise Jr KJ, Fife CE.
Simulated Flight Increases Lactate in Fetal Rabbits. Undersea and Hyperbaric Medical Society Annual, Scientific Meeting, Anchorage, Alaska, April 30-May 5, 1996. Undersea Hyperbaric Med. 23(S)120:78, 1996.
24. Swaby G, Brown S, Sutton T, Love T, Fife CE. Calibration of an End Tidal CO2
Monitor Under Hyperbaric Conditions. Undersea and Hyperbaric Medical Society, Annual Scientific Meeting, Anchorage, Alaska, April 30-May 5, 1996. Undersea Hyperbaric Med. 23(S), 1996.
25. Fife CE, Buyukcakir C, Otto G, Pontani B, Sheffield P, Mader J, Harrist R. Predicting
Outcome in Diabetics Undergoing Hyperbaric Oxygen Therapy for Nonhealing Lower Extremity Wounds: A Retrospective, Multi-Center Data Analysis of 1006 Patients. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, June 15-22, 1997. Undersea Hyperbaric Med. 24(S)42:16, 1997.
26. Schrader D, Parker K, Otto G, Fife CE. The Relationship Between Transcutaneous
Oximetry and Laser Skin Pressure Utilizing the Vasamedics Laser Doppler 2000. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, June 15-22, 1997. Undersea Hyperbaric Med. 24(S)11:11, 1997.
27. Fife CE, Cetina S. Initial Testing of the Mini Med 506 Insulin Pump in the Multiplace
Hyperbaric/Hypobaric Chamber. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, June 15-22, 1997. Undersea Hyperbaric Med. 24(S)11:11, 1997.
28. O’Malley E, Otto G, Berkowicz L, Suttle K, Kulikovsky M, Cetina S, Fife CE. Blood
Glucose Screening in Diabetics Undergoing Hyperbaric Oxygen Therapy. Undersea
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& Hyperbaric Medical Society Annual Scientific Meeting, Seattle, WA, May 21-23, 1998. Undersea Hyperbaric Med. 25(S)147:49, 1998.
29. Fife CE, Buyukcakir C, Otto G, Love T, Finn C, Pontani B. Outcome in Diabetic
Nonhealing Lower Extremity Wounds: Validation of a Predictive Model. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Seattle WA, May 21-23, 1998, Undersea Hyperbaric Med. 25(S)73:28, 1998
30. Dedi D, Prager T, Jacob R, Chan A, Fife CE. Visual Acuity Changes in Patients
Undergoing Hyperbaric Oxygen Therapy. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Seattle, WA, May 21-23, 1998. Undersea and Hyperbaric Med. 25(S)93:34, 1998.
31. Landers M, Otto GH, Posey K, Sutton T, Smith L, Aristizabal J, Fife CE. Neurological
Disorders In Patients Presenting with DCI. Undersea and Hyperbaric Medical Society Annual Meeting, Stockholm, Sweden, June 18-20, 2000.
32. Conkin J, Gernhardt ML, Foster PP, Pilmanis AA, Butler BD, Beltran E, Fife CE,
Vann RD, Gerth WA, Loftin KC, Acock K, Dervay JP, Waligora JM, Powell MR, Feivesont AH, Nishi,RY, Sullivan PA, Schneider SM. Relationship of Exercise, Age, and Gender on Decompression Sickness and Venous Gas Emboli During a 2-Hour Oxygen Prebreathe Prior to Hypobaric exposure. Undersea Hyperb Med 27(Supp): A10, 2000 118.
33. Gernhardt ML, Conkin J, Foster PP, Pilmanis AA, Butler BD, Beltran E, Fife CE,
Vann RD, Gerth WA, Loftin KC, Acock K, Dervay JP, Waligora JM, Powell MR Feiveson AH, Nish RY, Sullivan PA, and Schneider SM. Design and testing of a 2-hour oxygen prebrathe protocol for space walks from the International Space Station. Undersea and Hyperbaric Med. 27:S12, 2000.
34. Kulikovsky M, Otto GH, Smith L, Aristizabal J, Brown SD, Sutton T, Fife CE: Routine
Pulmonary Function Tests Prior to Hyperbaric Oxygen Therapy Are Not Indicated. Undersea and Hyperbaric Medical Society Annual Meeting, Stockholm, Sweden, June 18-20, 2000.
35. Ross C, Otto G, Smith L, Fife CE. The Combined Use of Hyperbaric Oxygen Therapy
and the Negative Pressure Wound Dressing (the ”VAC”) in Limb Threatening Wounds. Undersea and Hyperbaric Medical Society Annual Meeting, Quebec City, Canada, 2003. Undersea Hyperbaric Med. 33(2 Suppl), 2003.
36. St Leger Dowse M, Gunby A, Moncad R, Fife CE, Bryson P. The Perceived Effect of
Menstruation on Diving Incidents: A Three-year Prospective Observational Study. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Quebec City, Canada, 2003. Undersea Hyperbaric Med. 33(2 Suppl), 2003.
37. St Leger Dowse M, Gunby A, Moncad R, Fife CE, Bryson P. A Prospective
Observational Study of Reverse Diving Profiles (RDP) in UK Female Recreational Divers. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Quebec City, Canada, 2003. Undersea Hyperbaric Med. 33(2 Suppl), 2003.
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38. Swaby K, Smith L, Fife CE, Swaby G. Preventing Carbon Monoxide Poisoning in a Migratory Community. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Quebec City, Canada, 2003. Undersea Hyperbaric Med. 33(2 Suppl), 2003.
39. Conley J, Swaby K, Otto G, Smith L, Fife CE, Ross C. Blood Glucose Changes and
the Effects of Feeding in Diabetics Undergoing Hyperbaric Oxygen Therapy. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Quebec City, Canada, 2003. Undersea Hyperbaric Med. 33(2 Suppl), 2003.
40. Swaby K, Conley J, Otto G, Smith L, Ross C, Fife CE. A Prospective Study of
Feeding to Prevent Hypoglycemia in Diabetics Undergoing Hyperbaric Oxygen Therapy. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Quebec City, Canada, 2003.
41. Swaby K, Ross C, Sutton T, Swaby G, Benavidez TE, Berry JA, Fife CE. Alternative
Breathing Gas Delivery System for Tracheostomy Patients in the Multiplace Hyperbaric Chamber. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Quebec City, Canada, 2003.
42. Swaby K, Swaby G, Fife CE, Smith L. Testing Considerations for Fluid Infusion
Systems Used in the Hyperbaric Environment. Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Quebec City, 2003.
43. Fife CE, Smith L, Warriner RA, Sheffield PJ, Schmitz G, Ramos J, Swaby K, Otto G.
Is There an Ideal Treatment Pressure? Treatment at 2.0 VS 2.4 ATA: the Effect of Treatment Pressure on Transcutaneous Oximetry (TCOM). Undersea and Hyperbaric Medical Society Meeting, May 25-28, 2004, Sydney, Australia.
44. Fife CE, Otto GH, Walker D, Thomson B. The Effectiveness of Negative Pressure
Wound Therapy (NPWT) Using Open Cell Foam (OCF) in the Treatment of Diabetic Foot Ulcers in an Outpatient Setting. Third Congress of the World Union of Wound Healing Societies, Toronto, Canada, June 4-8, 2008.
45. Carter MJ, Fife CE, Walker D, Thomson B. An Estimate of the Applicability of
Wound-care Randomized Controlled Trials to General Wound-care Populations Based on Exclusion Criteria. Third Congress of the World Union of Wound Healing Societies, Toronto, Canada, June 4-8, 2008.
46. Fife CE, Otto GH, Walker D, Thomson B. The Safety of Negative Pressure Wound
Therapy in the Outpatient Setting. Third Congress of the World Union of Wound Healing Societies, Toronto, Canada, June 4-8, 2008.
47. Fife CE, Otto GH, Walker D, Thomson B. The Use of Advanced Therapeutics
Including Negative Pressure Wound Therapy in 8,611 patients Treated at 11 U.S. Outpatient Wound Centers. Third Congress of the World Union of Wound Healing Societies, Toronto, Canada, June 4-8, 2008.
48. Rasmussen JR, Tan I-C, Marshall MV, Sharma R, Fife CE, Maus EA, Smith LA, Sevick-
Muraca EM. Lymphatic Imaging in Normal Subjects and in Persons with Lymphedema. World Molecular Imaging Conference, Nice, France, September 2008.
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49. Rasmussen JC, Tan IC, Marshall MV, Adams KE, Kwon S, Fife CE, Maus EA, Smith LA, Sevick-Muraca EM. Characterization of Human Lymphatic Architecture and (Dys)function with Near-infrared Fluorescence Imaging,” World Molecular Imaging Congress, Montreal, Canada, September 2009.
50. Marshall MV, Rasmussen JC, Tan I-C, Adams KE, Fife C, Smith L, Maus EA, Sevick-
Muraca EM. Near infrared (NIR) Imaging of Lymphatic Function in Control Subjects and in Persons with Lymphedema. The Toxicologist. 108(1); 233, 2009.
51. Rasmussen JC, Marshall MV, Tan IC, Adams KE, Aldrich MB, Wang X, Fife CE,
Maus EA, Smith LA, Sevick-Muraca EM. Noninvasive Characterization of Lymphatic Architecture and Function in Control and Lymphedema Subjects Using Near-infrared Fluorescence Imaging. 18th International Workshop on Vascular Anomalies, Brussels, Belgium, April 2010. (winner of best clinical paper award)
52. Tan IC, Rasmussen J, Marshall M, Maus E, Fife C, Smith L, Sevick-Muraca EM. “NIR
Fluorescent Imaging to Evaluate Massage as a Lymphedema Therapy”, 57th Annual Meeting of Society of Nuclear Medicine, Salt Lake City, Utah, June 2010. (winner of Molecular Imaging Center of Excellence Young Investigator Award)
53. Marshall MV, Rasmussen JC, Tan IC, Aldrich MB, Adams KE, Drane C, Fife CE,
Smith LA, Maus EA, Hoy S, Sevick-Muraca EM. Fluorescent Molecular Imaging and Microdosing in Humans. World Molecular Imaging Congress, Kyoto, Japan, September 8-11, 2010.
54. Rasmussen JC, Tan I-C, Marshall MV, Adams KE, Kwon S, Fife CE, Maus EA, Smith LA, Sevick-Muraca EM. Assessing Lymphatic Architecture and Function in Health and Disease Using Near-infrared Fluorescence Imaging. 3rd International Lymphoedema Framework Conference, Toronto, Canada, June 16-18, 2011.
55. Tan IC, Maus EA, Rasmussen JC, Marshall MV, Fife CE, Smith LA, Sevick-Muraca EM. Near-infrared Fluorescence Imaging of Lymphatics in Head and Neck Lymphedema. 3rd International Lymphoedema Framework Conference, Toronto, Canada, June 16-18, 2011.
56. Rasmussen JC, Herbst KL, Aldrich MB, Darne D, Tan I-C, Zhu B, Guilliod R, Fife CE, Maus EA, Sevick-Muraca EM. Lymphatics in Adipose Disorders. 19th International Workshop on Vascular Anomalies, Malmo, Sweden, June 16-19, 2012.
57. Sevick-Muraca E, Agollah, G, Fife C, Rasmussen J, Gonzalez-Garay M. Phenotyping Lymphatic Abnormalities with Near-infrared Fluorescence Lymphatic Imaging for Accurate Genotyping with Next Generation Sequencing. 20th International Workshop on Vascular Anomalies, Melbourne, Australia, April 4, 2014.