I

CURRICULUM VITAE

Personal details

PD Dr. med. Bruno Markus Balsiger

Business addresses

Gastroenterologische Praxis Balsiger, Seibold & Partner Crohn-Colitis-Zentrum Bremgartenstrasse 119 CH – 3012 Bern Phone +41 31 302 32 34 Fax +41 302 32 35 E-Mail: bern@magendarmsuisse.ch

Cabinet de gastro-entérologie Balsiger, Seibold & Partner Centre Crohn Colitis Chemin des Pensionnats 1 1700 Fribourg T 026 916 32 34 F 026 916 32 35

Privat address Jetzikofenstrasse 16, CH – 3038 Kirchlindach

Date of birth 5/3/1963

Citizien of Switzerland

Marial status Married with Dorothea Anna Kuratle

Children 4 Lukas Michaja, 9/16/1991

Annina Lena, 9/20/1993

Laura Tabea, 6/28/1995

Kayla Rebecca, 6/05/1998

Languages German (native language), English and French

Bern, August 13th, 2019

- 1 -

Work as medical doctor

2015 until today Externer leitender Arzt Gastroenterologie Kantonspital Fribourg

2008 until today Founder and co-owner of Gastroenterologische Praxis Balsiger, Seibold und Partner

2007 – 2008 Junior Consultant (Stv. Oberarzt) Spitalbern Tiefenau Medizin Jan 1, 2007 - April 30, 2008 (Prof. H.R. Baur)

2006 – 2006 Resident at the University of Basel, Gastroenterology Unit, Jan 1 – Dec 31, 2006 (Chairman: Prof. C. Beglinger)

2002 – 2005 Resident at the University of Berne, Gastroenterology Unit, Dec 1, 2002 – Dec 31, 2005 (Chairman: Prof. H.U. Scheurer)

2003 – 2004 Consultant (Oberarzt) for outpatient obesity program University of Berne Endocrinology Unit Aug 1, 2003 - June 30, 2004 (Chairman: PD P. Diem)

2000 – 2004 Within the scope of a Swiss Government academic support position (“Bundesförderungsstelle”), Oct 1, 2000 till Sept 30, 2004 and regular position since Oct 1, 2004

2001 – 2002 Consultant (Oberarzt) Dept. of Surgery Hospital Center of Biel (clinical work) and at the University of Berne, Department of Visceral and Transplantation Surgery (re- search) May 1, 2001- Nov 30, 2002 (Chairmen: Prof. M.W. Büchler/Prof. D. Candinas, Bern and Prof.U.Laffer, Biel)

2001 – 2001 Consultant (Oberarzt) at the University of Berne, Department of Visceral and Trans- plantation Surgery Jan 1, 2001- April 30, 2001 (Chairman: Prof. M.W. Büchler)

1999 – 2001 Responsible for obesity surgery patient program, including preoperative and postoperative care and follow up 1994 -1996 and 1999 -2001

2000 – 2000 Collaboration in outpatient program for Patients with inflammatory bowel disease. Jan 1 - Dec 31, 2000

Senior resident at the University of Berne, Department of Visceral and Transplantation Surgery, Oct 1, 2000 - Dec 31, 2000 (Chairman: Prof. M.W. Büchler)

Resident at the University of Berne, Department of Visceral and Transplantation Surgery, June 1, 2000 - September 30, 2000 (Chairman: Prof. M.W. Büchler)

Research Fellow at the Gastroenterology Research Unit, Mayo Clinic, Rochester, Minnesota, USA, March 1 - May 31, 2000 (Prof. M.G. Sarr)

1999 – 2000 University of Berne, Department of Visceral and Transplantation Surgery, July 1, 1999 - February 29, 2000 (Chairman: Prof. M.W. Büchler)

- 2 -

1996 – 1999 Research Fellow at the Gastroenterology Research Unit, Mayo Clinic, Rochester, Minnesota, USA, May 1, 1996 - June 30, 1999 (Prof. M.G. Sarr)

1994 – 1996 Resident at the University of Berne, Department of Visceral and Transplantation Surgery July 1, 1994- April 30, 1996 (Chairman: Prof. M.W. Büchler)

Responsible for obesity surgery patient program, including preoperative and postoperative care and follow up 1994 -1996 and 1999 -2001

1992 – 1994 Resident in the Hospital of Wattenwil Surgery/ Gynecology/ Internal Medicine from June 12, 1992- June 30, 1994 (Dr. B. Roth, Dr. R. Barandun, Dr. N. von Rechenberg)

1991 – 1991 Medical resident in the section for autopsy at the Institute of Pathology of the University of Berne Jan 1- Dec 31, 1991 (Prof.J. Laissue, Prof. T. Schaffner)

School education All schools absolved in Berne (4 years Primary School, 4 years Secondary School,

4 1/2 years Grammar School with finals in 1982)

Studies Studies of medicine at the Medical Faculty of the University of Berne 1983-1990

Final exams in 1989 and 1990

Promotion Promotion as Dr. med. July 26, 1993 Prof. Dr. med. U. Boschung, Institute of medical History, Universitiy of Berne

Venia Docendi Habiltiation in experimental Gastroenterology, venia docendi University of Bern, Nov 2005

Additional training Certificate of AO course in basic treatment of fractures, Davos 2001

Certificate of Gastrointestinal Surgery course of the

international society for gastrointestinal surgery,

Davos 2002

Certification for Advanced Trauma and Live Support (ATLS), Zurich 2002

Specially selected abstracts

Society for Surgery of the Alimentary Tract, Annual meeting May 17 - 20, 1998, New Orleans, USA SSAT and Ross Resident’s conference May 16th 1998, invitation and nomination (one of the best twenty abstracts) for the abstract: Small bowel transplantation (SBT) alters non-adrenergic non-

- 3 -

cholinergic (NANC) inhibition in longitudinal smooth muscle of the rat jejunum.

European Society for Surgical Research, 34th congress, April 22-24, 1999, Bern, Switzerland Nomination for Walter Brendel Session (second highest scoring abstract out of 500) with the abstract: Chronic lack of extrinsic neural input increases nitric oxide (NO) independent inhibition after rat small bowel transplantation (SBT).

Society for Surgery of the Alimentary Tract, Annual meeting May 16 - 19, 1999, Orlando, USA SSAT and Ross Resident’s conference May 15th 1998, invitation and nomination (one of the best twenty abstracts) for the abstract: Roux-en-Y gastric bypass as a remedial operation for gastroesophageal reflux (GER) after vertical banded gastroplasty (VBG)

Day of clinical research, University of Bern, Nov 13, 2002, Bern, Switzerland: third highest scoring of work performed by medical students (Seiler R) Muscular and neuronal adrenergic receptor mechanisms in rat ileal longitudinal muscle contractility.

Society for Surgery of the Alimentary Tract, Annual meeting May 18 - 21, 2003, Orlando, USA SSAT residents and fellows research conference May 17th 2003, invitation and nomination (one of the best twenty abstracts) for the abstract: Acute pancreatitis induces ileus by upregulating TNF and Nitric Oxide in the small intestine.

Grants and scholarships

1996-97 Department of Visceral and Transplantation Surgery, University of Bern: support for: The effects of small bowel autotransplantation on jejunal and ileal circular smooth muscle function in vitro in dogs.

1997 Astra Pharmaceuticals, Switzerland: support for: The effects of small bowel autotransplantation on jejunal and ileal circular smooth muscle function in vitro in dogs.

1997 Novartis Nutrition: support for: The effects of small bowel autotransplantation on jejunal and ileal circular smooth muscle function in vitro in dogs

1997-98 Swiss National Science Foundation: fellowship for prospective researchers for the project: The role of nitric oxide in rat jejunal and ileal longitudinal smooth muscle before and after small bowel transplantation.

1998 Novartis Foundation: support for: The effects of small bowel autotransplantation on jejunal and ileal circular smooth muscle function in vitro in dogs.

1998 Swiss Society for Gastroenterology and Hepatology: support in addition for: The role of nitric oxide in rat jejunal and ileal longitudinal smooth muscle before and after small bowel transplantation.

- 4 -

1998-99 Swiss Foundation for medical and biological science: fellowship for advanced researchers for a project extension (results one year after transplantation): The role of nitric oxide in rat jejunal and ileal longitudinal smooth muscle before and after small bowel transplantation.

1998 Special Credit University of Bern: High Tech 5ml, 12 channel organchamber system including electro stimulation and computer hard and software.

1999 Department of Clinical Research, University of Bern: Grant in aid for: Neuromuscular transmission and control of smooth muscle activity in the human intestine.

2000 Special Credit University of Bern: Eight additional high Tech 10ml organchambers

2001 (August) – 2003 (July) Swiss National Science Foundation project grant: (Nr.3100-061583) : Small bowel transplantation: changes in receptor specific adrenergic neuromuscular mechanisms in the rat ileum

2000 (Oct 1) – 2004 (Sept 30) Swiss Government academic support position (“Bundesförderungsstelle”)

2003 (August 1) – 2004 (Sept 30) Special extension of Swiss National Science Foundation project grant: (Nr. 3100-061583) : Small bowel transplantation: changes in receptor specific adrenergic neuromuscular mechanisms in the rat ileum

Active Collaboration

• Prof. Jukka Takala, Chair: Intensiv Care Unit, University of Bern, Inselspital, Bern Effect of endotoxin on contractile properties of splanchnic vasculature and small bowel in pigs.

• Dr. Sidney Shaw, Departement of clinical research, University of Bern

• Prof. U. Honegger, Departement of Pharmacology, University of Bern

• Michel Murr, MD, associate Professor of Surgery, University of South Florida, Tampa, FL, USA

• Michael Sarr, MD, Professor of Surgery and Chair General and Gastrointestinal Surgery, Mayo Clinic, Rochester, MN, USA

• PD J. Gschossmann, Departement of Gastroenterology, University of Bern

• Prof. Ch. Beglinger, Departement of Gastroenterology, University of Basel

•

- 5 -

Memberships • ABV - Aerztlicher Bezirksverein Bern Regio

• AGA - the American gastroenterological association

• Aerztegesellschaft des Kantons Bern

• Aerztlicher Bezirkverein Biel - Seeland

• ASGE - American society for gastrointestinal endoscopy

• ATLS - Advanced Trauma and Life Support

• DAG - Deutsche Adipositas-Gesellschaft

• ECCO - European Crohn's and Colitis Organisation

• EFSUMB - European Federation of Societies for Ultrasound in Medicine & Biology

• European Digestive Surgery

• International Federation for the Surgery of Obesity

• Magendarmliga Schweiz

• SGGSSG - Schweizerische Gesellschaft für Gastroenterologie

• SSAT - The society for surgery of the alimentary tract

• SSUM-SGUM Schweiz. Gesellschaft für Ultraschall in der Medizin

• Swiss Study Group for Morbid Obesity

• Verein Ärztekollegium Lindenhofspital

Publications

Original articles in peer reviewed journals

1. Seiler CA, Balsiger BM, Feodorovici M, Baer HU, Büchler MW. Extensive intraoperative lavage: the key maneuver in the treatment of severe peritonitis. Dig Surg 1996;13:400-404 (IMPF 0.645; R 95/139)

2. Shibata C, Balsiger BM, Anding WJ, Sarr MG. Adrenergic denervation hypersensitivity in ileal smooth muscle after small bowel transplantation in rats. Dig Dis Sci 1997; 42: 2213-2221 (IMPF 1.438; R 27/45)

3. Shibata C, Murr MM, Balsiger BM, Anding WJ, Sarr MG. Contractile activity of smooth muscle in rats 1 year after small bowel transplantation: differing adaptive response of the jejunum and ileum to denervation. J Gastrointest Surg 1998; 2:463-472 (IMPF 1.99; 28/141)

4. Shibata C, Balsiger BM, Anding WJ, Duenes JA, Miller VM, Sarr MG. Functional changes in non-adrenergic non-cholinergic inhibitory neurons in ileal circular smooth muscle after small bowel transplantation in rats. Dig Dis Sci 1998; 43: 2446-2454 (IMPF 1.438 R 27/45)

5. Luque-de Leon E, Tsiotos GG, Balsiger BM, Barnwell J, Burgart LJ, Sarr MG. Staging Laparascopy for pancreatic cancer should be used to select the best means of palliation and not only to maximize resectability rate. J Gastrointestinal Surg. 1999;3:111-118 (IMPF 1.99; 28/141)

6. Murr MM, Balsiger BM, Kennedy FP, Mai JL, Sarr MG.

- 6 -

Malabsorptive Procedures for Severe Obesity: A Comparison of Pancreaticobiliary Bypass (PBB) and Very Very Long Limb Roux-en-Y Gastric Bypass (VVLGB). J Gastrointestinal Surg. 1998;3:607-612 (IMPF 1.99; 28/141)

7. Brugger LE, Seiler CA, Mettler M, Balsiger BM, Feodorovici M, Baer HU, Buchler MW: [New approaches to the surgical treatment of diffuse peritonitis]. Zentralbl Chir 124:181-6, 1999 (IMPF 0.259; 128/141)

8. Murr MM, Balsiger BM, Farrugia G, Sarr MG. Role of nitric oxide, VIP and ATP in inhibitory neurotransmission in human jejunum. J Surg Res. 1999;84:8-12 (IMPF 1.726; 34/141)

9. Murr, MM; Balsiger, BM; Farrugia, G; Sarr, MG Role of nitric oxide, vasoactive intestinal polypeptide, and ATP in inhibitory neurotransmission in human jejunum JOURNAL OF SURGICAL RESEARCH, 84 (1): 8-12 JUN 1 1999

10. Murr, MM; Balsiger, BM; Kennedy, FP; Mai, JL; Sarr, MG. Malabsorptive procedures for severe obesity: Comparison of pancreaticobiliary bypass and very long limb Roux-en-Y gastric bypass. JOURNAL OF GASTROINTESTINAL SURGERY, 3 (6): 607-612 NOV-DEC 1999

11. Ohtani N, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Small bowel transplantation induces adrenergic denervation-hypersensitivity in ileal longitudinal smooth muscles in rats. J Gastrointest Surg 2000;4:77-85 (IMPF 1.99; 28/141)

12. Naef M, Sadowski C, de Marco D, Sabbioni M, Balsiger BM, Laederach K, Burgi U, Buchler MW: [Mason vertical gastroplasty in treatment of morbid obesity. Results of a prospective clinical study]. Chirurg 71:448-55, 2000 (IMPF 0.848; 72/141)

13. Balsiger BM, Kennedy FP, Abu-Lebdeh HS, et al. Prospective evaluation of Roux- en-Y gastric bypass as primary operation for medically complicated obesity [see comments]. Mayo Clin Proc 2000; 75(7):673-80. (IMPF 2.868; 14/107)

14. Balsiger BM, Murr MM, Mai J, Sarr MG. Gastroesophageal reflux after intact vertical banded gastroplasty: correction by conversion to Roux-en-Y gastric bypass. J Gastrointest Surg 2000; 4(3):276-81. (IMPF 1.99; 28/141)

15. Balsiger BM, Poggio JL, Mai J, Sarr MG. Ten and more years after Vertical banded gastroplasty as primary operation for morbid obesity. J Gastrointest Surg 2000;4:598-605 (IMPF 1.99; 28/141)

16. Sakorafas, GH; Tsiotou, AG; Balsiger, BM. Axillary lymph node dissection in breast cancer - Current status and controversies,

- 7 -

alternative strategies and future perspectives. ACTA ONCOLOGICA, 39 (4): 455-466 2000

17. Ohtani, N; Balsiger, BM; Anding, WJ; Duenes, JA; Sarr, MG Small bowel transplantation induces adrenergic hypersensitivity in ileal longitudinal smooth muscle in rats. JOURNAL OF GASTROINTESTINAL SURGERY, 4 (1): 77-84 JAN-FEB 2000

18. Balsiger, BM; Murr, MM; Poggio, JL; Sarr, MG Bariatric surgery - Surgery for weight control in patients with morbid obesity. MEDICAL CLINICS OF NORTH AMERICA, 84 (2): 477-+ MAR 2000

19. Balsiger, BM; Kennedy, FP; Abu-Lebdeh, HS; Collazo-Clavell, M; Jensen, MD; O'Brien, T; Hensrud, DD; Dinneen, SF; Thompson, GB; Que, FG; Williams, DE; Clark, MM; Grant, JE; Frick, MS; Mueller, RA; Mai, JL; Sarr, MG. Prospective evaluation of Roux-en-Y gastric bypass as primary operation for medically complicated obesity. MAYO CLINIC PROCEEDINGS, 75 (7): 673-680 JUL 2000

20. Balsiger BM, Duenes JA, Ohtani N, Shibata C, Farrugia G, Anding WJ, Sarr MG. Nitric oxide pathways in circular muscle of the rat jejunum before and after small bowel transplantation. J Gastrointest Surg 2000;4:86-92 (IMPF 1.99; 28/141)

21. Balsiger BM, Ohtani N, Anding WJ, Duenes JA, Zinsmeister AR, Sarr MG: Chronic extrinsic denervation after small bowel transplantation in rat jejunum: effects and adaptation in nitrergic and non-nitrergic neuromuscular inhibitory mechanisms. Surgery 129:478-89. 2001(IMPF 2.631; R 12/141)

22. Zyromski NJ, Duenes JA, Kendrick ML, Balsiger BM, Farrugia G, Sarr MG: Mechanism mediating nitric oxide induced inhibition in human jejunal longitudinal smooth muscle. Surgery 130:489-96. 2001 (IMPF 2.631; R 12/141)

23. Zyromski, NJ; Duenes, JA; Kendrick, ML; Balsiger, BM; Farrugia, G; Sarr, MG. Mechanism mediating nitric oxide-induced inhibition in human jejunal longitudinal smooth muscle SURGERY, 130 (3): 489-496 SEP 2001

24. Sabbioni ME, Dickson MH, Eychmüller S, Franke D, Goetz S, Hürny Ch, Naef M, Balsiger BM, de Marco Doris, Bürgi U, Büchler MW: Intermediate results of health related quality of life after vertical banded gastroplasty. Int J Obes Relat Metab Disord 26:277-80. 2002 (IMPF 2.363; 38/88)

25. Balsiger BM, Rickenbacher A, Biecker E, Tsui J, Dashwood M, Reichen J, Shaw S.G: Endotheline A-receptor blockade in experimental diabetes improves Glucose balance and gastrointestinal function. Clin Sci (Lond) 103 Suppl 1:430S-3S.

- 8 -

2002 (IMPF 1.941; 28/74)

26. Balsiger, BM; He, CL; Zyromski, NJ; Sarr, MG Neuronal adrenergic and muscular cholinergic contractile hypersensitivity in canine jejunum after extrinsic denervation JOURNAL OF GASTROINTESTINAL SURGERY, 7 (4): 572-582 MAY-JUN 2003

27. Clark, MM; Balsiger, BM; Sletten, CD; Dahlman, KL; Ames, G; Williams, DE; Abu-Lebdeh, HS; Sarr, MG Psychosocial factors and 2-year outcome following bariatric surgery for weight loss OBESITY SURGERY, 13 (5): 739-745 OCT 2003

28. Seiler, R; Rickenbacher, A; Shaw, S; Balsiger, BM alpha- and beta-adrenergic receptor mechanisms in spontaneous contractile activity of rat ileal longitudinal smooth muscle JOURNAL OF GASTROINTESTINAL SURGERY, 9 (2): 227-235 FEB 2005

29. Balsiger, BM (Balsiger, Bruno M.); Ernst, D (Ernst, Daniel); Giachino, D (Giachino, Daniel); Bachmann, R (Bachmann, Ruedi); Glaettli, A (Glaettli, Andreas) Prospective evaluation and 7-year follow-up of swedish adjustable gastric banding in adults with extreme obesity JOURNAL OF GASTROINTESTINAL SURGERY, 11 (11): 1470-1476 NOV 2007

30. Schirmer, BD (Schirmer, Bruce D.); Balsiger, BM (Balsiger, Bruno M.); Mazeh, H (Mazeh, Haggi); Hungness, ES (Hungness, Eric S.) Prospective evaluation and 7-year follow-up of swedish adjustable gastric banding in adults with extreme obesity – Discussion JOURNAL OF GASTROINTESTINAL SURGERY, 11 (11): 1476-1477 NOV 2007

31. Rickenbacher, A (Rickenbacher, Andreas); Seiler, R (Seiler, Roland); Honegger, U (Honegger, Ulrich); Shaw, SG (Shaw, Sidney G.); Balsiger, BM (Balsiger, Bruno M.) Role of beta(1)-, beta 2-, and beta(3)-adrenoceptors in contractile hypersensitivity in a model of small bowel transplantation SURGERY, 143 (1): 94-102 JAN 2008

32. Seiler, R (Seiler, Roland); Rickenbacher, A (Rickenbacher, Andreas); Shaw, S (Shaw, Sidney); Haefliger, S (Haefliger, Simon); Balsiger, BM (Balsiger, Bruno M.) Role of selective alpha and beta adrenergic receptor mechanisms in rat jejunal longitudinal muscle contractility JOURNAL OF GASTROINTESTINAL SURGERY, 12 (6): 1087-1093 JUN 2008

33. Balsiger BM, He CL, Zyromski NJ, Sarr MG: Neuronal adrenergic and muscular cholinergic contractiele

- 9 -

hypersensitivity in canine jejunum after extrinsic denervation. J Gastrointest Surg. 2003 May-Jun;7(4):572-82 (IMPF 1.99; 28/141)

34. Balsiger BM, Sarr MG: Chronic extrinsic denervation of the small bowel: effect on adrenergic and cholinergic contractile mechanisms in canine ileal circular muscle. Surgery. 2003 Nov;134 (5):783-90. (IMPF 2.631; R 12/141)

35. Clark MM, Balsiger BM, Sletten CD, Litzinger KL, Wolff G, Williams DE, Abu-Leb- deh HS, Sarr MG: Psychologic factors as predictors of two-year outcome following bariatric surgery for weight loss. Obes Surg. 2003 Oct;13 (5):739-45. (IMPF 2.356; R20/141)

36. Seiler R, Rickenbacher A, Shaw SG, Balsiger BM: Role of α1, α2, β1, β2, and β3- Adrenergic Receptor Mechanisms in Spontaneous Contractile Activity of Rat Ileal Longitudinal Smooth Muscle. J Gastrointest Surg 2005; 9: 227-235 (IMPF 1.99; 28/141)

37. Muller S, Arni S, Varga L, Balsiger BM, Hersberger M, Maly F, Seibold F. Serological and DNA-based evaluation of Chlamydia pneumoniae infection in inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2006 Aug;18(8):889-94. (IMPF 1.69; 29/46)

38. Rickenbacher A, Seiler R, Honegger U, Shaw SG, Balsiger BM:

Role of β1-, β2-, and β3-Adrenoceptors in Contractile

Hypersensitivity in a Model of Small Bowel Transplantation.

Surgery 2008

Original work, not peer reviewed

1. Balsiger BM, Ohtani N, Farrugia G, Sarr MG. Delayed induction of K+-channel dependent non-nitrergic inhibition in longitudinal smooth muscle of rat jejunum. Proceedings of the Falk Symposium 112; 231-235. 2000, Kluwer Academic Publishers, Dordrecht, NL

Review articles in peer reviewed journals

1. Balsiger BM, Luque-de Leon E, Sarr MG. Surgical treatment of obesity: who is an appropriate candidate? Mayo Clin Proc 1997; 72:551-558 (IMPF 2.868; R 14/107)

2. Balsiger BM, Murr MM, Poggio JL, Sarr MG. Bariatric surgery. Surgery for weight control in patients with morbid obesity. Med Clin North Am 2000; 84(2):477-89 (IMPF 2.138; 20/107)

3. Sakorafas GH, Tsiotou AG, Balsiger BM: Axillary lymph node

- 10 -

dissection in breast cancer: current status and controversies, alternative strategies, and future perspectives. Acta Oncol 2000;39(4):455-466 (IMPF 1.909; 60/114)

4. Sakorafas GH, Friess H, Balsiger BM, Büchler MW, Sarr MG. Problems of reconstruction during pancreatoduodenectomy. Dig Surg 18:363-9, 2001 (IMPF 0.645; R 95/141)

Review articles, not peer reviewed

1. Sarr MG, Balsiger BM. Bariatric surgery in the 1990’s. Swiss Surg 2001;7:11-15

2. Gschossmann JM, Holtmann G, Netzer P, Essig M, Balsiger BM, Scheurer U.Abdominal pain Internist (Berl). 2005 Oct;46(10):1096-104. (IMPF 0.35; 88/105)

Abstracts, accepted and published

1. Balsiger BM, Schilling M, Naef M, Sabbioni M, DeMarco D, Bürgi U, Sterchi A, Büchler MW. Vertical Banded Gastroplasty (Mason) as a Surgical Therapy for Morbid Obesity. Preliminary Results. Swiss Surg. 1995; Suppl. 2:27

2. Balsiger BM, Baer HU, Seiler CA, Feodorovici M, Franz S, Büchler MW. Peritonitis: Herdsanierung, ausgedehnte intraoperative Peritoneal-Lavage und direkter Abdominalverschluss als Standardtherapie. Swiss Surg. 1996; Suppl. 3:37

3. Naef M, Balsiger BM, Baer HU, Sabbioni M, DeMarco D, Bürgi U, Sterchi A, Büchler MW. Vertical banded Gastroplasty nach Mason zur chirurgischen Therapie morbider Adipositas. Eine prospektive klinische Studie. Akt.Ernaehr-Med., 1996; 21:A258

4. Shibata C, Balsiger BM, Sarr MG. The extrinsic denervation of small bowel transplantation (SBT) induces adrenergic hypersensitivity in ileal but not jejunal smooth muscle - at least one interneuron site away from the adrenergic synapse. Gastroenterology, 1997; 112:A824

5. Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Differing adaptive responses of ileal and jejunal smooth muscle to denervation after small bowel transplantation. Gastroenterology, 1997; 112:A1473

6. Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Inhibitory neural function in ileal circular smooth muscle after rat small bowel transplantation: Nitric oxide has no role. Gastroenterology, 1997; 112:A824

7. Balsiger BM, Ohtani N, Shibata C, Murr MM, Anding WJ, Duenes JA, Sarr MG. Small bowel transplantation (SBT) alters non-adrenergic non-cholinergic (NANC) inhibition in longitudinal smooth muscle of the rat jejunum. Gastroenterology, 1998; 114:

- 11 -

A1377

8. Balsiger BM, Ohtani N, Shibata C, Sarr MG. Non-adrenergic non-cholinergic (NANC) inhibition in longitudinal smooth muscle of rat jejunum: minor role of nitric oxide (NO). Gastroenterology, 1998; 114: A 716

9. Murr MM, Balsiger BM, Kennedy FP, Sarr MG. Malabsorbtive procedures for severe obesity: comparison of pancreaticobiliary bypass (PBB) and very, very long Roux-en-Y gastric bypass (VVLGB). Gastroenterology, 1998; 114: A1412

10. Choi MG, Camilleri M, Balsiger BM, Farrugia G. Effect and mechanism of glibenclamide on longitudinal smooth muscle contractility in rat colon. Gastroenterology, 1998; 114: A733

11. Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. Staging laparascopy for pancreatic cancer should be used to select the best palliation, not to increase resection rate. Gastroenterology, 1998; 114: A1407

12. Luque-de Leon, E; Tsiotos, GG; Balsiger, BM; Barnwell, J; Burgart, L; Sarr, MG. Staging laparoscopy for pancreatic cancer should be used to select the best palliation, not to increase resection rate. GASTROENTEROLOGY, 114 (4): S0149 Part 2 Suppl. S APR 15 1998

13. Balsiger BM, Ohtani N, Anding WJ, Duenes JA, Sarr MG. Chronic lack of extrinsic neural input increases nitric oxide (NO) independent inhibition after rat small bowel transplantation (SBT). Eur Surg Res 1999;31(suppl 1):1

14. Balsiger BM, Sarr MG. Roux-en-Y gastric bypass (RYGB) as primary operation for morbid obesity at the Mayo clinic. Eur Surg Res 1999;31(suppl 1): 8

15. Ohtani N, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Small bowel transplantation induces adrenergic denervation-hypersensitivity in ileal longitudinal smooth muscles in rats. Gastroenterology, 1999; 116: A1349

16. Ohtani N, Balsiger BM, Duenes JA, Sarr MG. Nitric oxide mediates non-adrenergic non-cholinergic (NANC) inhibition in ileal longitudinal smooth muscle of rats. Gastroenterology, 1999; 116: A1349

17. Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Extrinsic denervation of canine jejunum causes neuronal adrenergic and muscular cholinergic hypersensitivity. Gastroenterology, 1999; 116: A1075

18. Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Neural inhibition in jejunal circular muscle after small bowel transplantation (SBT): nitric oxide (NO) has no apparent role. Gastroenterology, 1999; 116: A1349

19. Balsiger, BM; Duenes, JA; Ohtani, N; Sarr, MG. Adenosine triphospate (ATP) inhibits canine jejunal contractions by

- 12 -

neuronal release of nitric oxide (NO). GASTROENTEROLOGY, 116 (4): G4670 Part 2 APR 1999

20. Balsiger BM, Murr MM, Sarr MG. Roux-en-Y gastric bypass as a remedial operation for gastroesophageal reflux (GER) after vertical banded gastroplasty (VBG). Gastroenterology, 1999; 116: A1348

21. Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Adenosine triphosphate (ATP) inhibits canine jejunal contractions by neuronal release of nitric oxide (NO). Gastroenterology, 1999; 116: A1076

22. Lee JS, Farrugia G, Balsiger BM, Camilleri M. Glibenclamide protection of colonic longitudinal smooth muscle contractile response to hypoxia in rats demaonstrates a physiological role of KATP channels. On longitudinal smooth muscle contractility in rat colon. Gastroenterology, 1999; 116: A1026

23. Balsiger, BM; Duenes, JA; Ohtani, N; Sarr, MG Adrenergic and cholinergic contractile mechanisms adapt after chronic extrinsic denervation of the small bowel. GASTROENTEROLOGY, 118 (4): 2088 Part 1 Suppl. 2 APR 2000

24. Balsiger, BM; Kelly, KA; Poggio, JL; Mai, J; Sarr, MG Long-term prospective follow-up (> 10 years) after vertical banded gastroplasty (VBG). GASTROENTEROLOGY, 118 (4): 3897 Part 1 Suppl. 2 APR 2000

25. Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Adrenergic contractile mechanisms adapt after chronic extrinsic denervation of the canine small bowel. Gastroenterology, 2000; 118(4): A2088

26. Balsiger BM, Poggio JL, Mai J, Sarr MG. Ten and more years after Vertical banded gastroplasty as primary operation for morbid obesity. Gastroenterology, 2000; 118(4): A3897

27. Balsiger BM, Sarr MG, Duenes JA, Anding WJ. Downregulation of nitric oxide dependent inhibition in rat jejunum one year after small bowel transplantation (SBT). Dig. Surg., 2000: 17: 124

28. Balsiger BM, Seiler R, Rickenbacher A, Müller J, Shaw SG: Muscular and neuronal adrenergic receptor mechanisms in rat ileal longitudinal muscle contractility. Gastroenterology, 2002; 123(1): 1249

29. Balsiger, BM; Seiler, R; Rickenbacher, A; Muller, J; Shaw, S. Muscular and neuronal alpha and beta adrenercig receptor mechanisms in rat ileal longitudinal muscle contractility. GASTROENTEROLOGY, 123 (1): 20-20 Suppl. S JUL 2002

30. Seiler R, Rickenbacher A, Müller J, Shaw SG, Balsiger BM: Role of α and β adrenergic receptor mechanisms in rat jejunal longitudinal muscle contractility. Gastroenterology, 2003; 124(1): 1342

- 13 -

31. Rickenbacher A, Seiler R, Müller J, Shaw SG, Balsiger BM: Role of β1, β2 and β3 receptor contractile mechanisms in adrenergic hypersensitivity after small bowel transplantation. Gastroenterology, 2003; 124(1): 1332

32. Rickenbacher A, Gallagher SF, Yang J, Balsiger BM, Gower WR, Norman JG, Murr MM: Acute pancreatitis induces ileus by upregulating TNF and Nitric Oxide in the small intestine. Gastroenterology, 2003; 124(1): 1331

33. Rickenbacher, A; Seiler, R; Mueller, J; Shaw, SG; Balsiger, BM Role of B1, B2 and B3 receptor contractile mechanisms in adrenergic hypersensitivity after small bowel transplantation GASTROENTEROLOGY, 124 (4): A797-A797 Suppl. S APR 2003

34. Seiler, R; Rickenbacher, A; Shaw, SG; Balsiger, BM Role of A and B adrenergic receptor mechanisms in rat jejurial longitudinal muscle contractility GASTROENTEROLOGY, 124 (4): A799-A799 Suppl. S APR 2003

35. Haefliger Simon, Seiler R, Rickenbacher A, Shaw SG, Balsiger BM: Differential role of nitric oxide in longitudinal and circular muscle of the rat colon. Gastroenterology, 2005; April suppl.

36. Balsiger, BM (Balsiger, Bruno M.); Hubacher, T (Hubacher, Thomas); Baumgartner, C (Baumgartner, Christine); Tovar, L (Tovar, Luis); Oulevey, M (Oulevey, Mareike); Knuesel, C (Knuesel, Christian); Essig, M (Essig, Manfred); Scheurer, U (Scheurer, Ulrich); Gschossmann, JM (Gschossmann, Juergen M.) Colonic hypomotility associated with butyrate-induced non-inflammatory hypersensitivity of the colon can be restored by estrogen substitution in ovariectomized rats GASTROENTEROLOGY, 132 (4): A41-A41 Suppl. 2 APR 2007

37. Balsiger, BM (Balsiger, Bruno M.); Giachino, D (Giachino, Daniel); Bachmann, R (Bachmann, Ruedi); Glaettli, A (Glaettli, Andreas) Seven year follow-up after Swedish laparoscopic gastric banding (SAGB) GASTROENTEROLOGY, 132 (4): A837-A837 Suppl. 2 APR 2007

38. Balsiger, BM (Balsiger, Bruno M.); Sterchi, A (Sterchi, Anna) Macro- and micronutrients in morbid obese patients before and after restrictive bariatric surgery GASTROENTEROLOGY, 132 (4): A880-A880 Suppl. 2 APR 2007

39. Balsiger, BM (Balsiger, Bruno M.); Hubacher, T (Hubacher, Thomas); Baumgartner, C (Baumgartner, Christine); Tovar, LA (Tovar, Luis A.); Knusel, C (Knusel, Christian); Flogerzi, B (Flogerzi, Beatrice); Rickenbacher, A (Rickenbacher, Andreas); Essig, M (Essig, Manfred); Scheurer, U (Scheurer, Ulrich); Gschossmann, JM (Gschossmann, Juergen M.) Effect of sexual hormones on cholinergic and adrenergic contractile mechanisms of colonic smooth muscle strips in an in vitro model of naive female rats. GASTROENTEROLOGY, 134 (4): A64-A64 Suppl. 1 APR 2008

- 14 -

40. Krayer, M (Krayer, Magali); Knusel, C (Knusel, Christian); Oulevey, M (Oulevey, Mareike); Flogerzi, B (Flogerzi, Beatrice); Tovar, LA (Tovar, Luis A.); Balsiger, BM (Balsiger, Bruno M.); Essig, M (Essig, Manfred); Scheurer, U (Scheurer, Ulrich); Gschossmann, JM (Gschossmann, Juergen M.) Effect of estrogen on visceral sensory function in a non-inflammatory colonic hypersensitivity rat model GASTROENTEROLOGY, 134 (4): A554-A555 Suppl. 1 APR 2008

41. Balsiger, BM (Balsiger, Bruno M.); Maecker, F (Maecker, Folkert); Glaettli, A (Glaettli, Andreas) Long-term outcome after distal gastric bypass combined with Swedish adjustable gastric banding (SAGB) GASTROENTEROLOGY, 134 (4): A871-A872 Suppl. 1 APR 2008

42. Balsiger BM, Krayer M, Rickenbacher A, Flogerzi B, Vennos C, Gschossmann JM. Tibetan herbal formula Padma Digestin modulates gastrointestinal motility in vitro. World J Gastrointest Pharmacol Ther. 2013 Feb 6;4(1):9-15. doi: 10.4292/wjgpt.v4.i1.9.

43. Gorrasi J, Jakob SM, Tovar L, Balsiger B, Brandt S, Bruegger

LE, Bracht H, Takala J. Shock. Perioperative Fluid

Accumulation Impairs Intestinal Contractility to a Smilar Extent

as Peritonitis and Endotoxemia.

2017 Dec 14. doi: 10.1097/SHK.0000000000001088.[Epub

ahead of print]

Book chapters

1. Balsiger BM, Seiler CA, Büchler MW. Peritonitis: Herdsanierung und intraoperativ extensive Lavage als Standardtherapie. In: Köckerling F, Hohenberger W, Teichmann W, eds. Intraabdominelle Infektionen. Heidelberg Leipzig: Barth, 1996 169-173

2. Sarr MG, Sakorafas GH, Balsiger BM, Farley DR. The spectrum of cystic neoplasms of the pancreas. In Dervenis C, ed. Pancreatic tumors: achievements and prospective. 2000. Thieme. Stuttgart

Presentations of papers on meetings and congresses

1. Balsiger B.M., Schilling M, Naef M, Sabbioni M, DeMarco D, Bürgi U, Sterchi A, Büchler MW. Vertical Banded Gastroplasty (Mason) as a Surgical Therapy for Morbid Obesity. Preliminary Results. Swiss association of Surgery: 82. annual congress, June 8-10, 1995, Lugano, Switzerland

- 15 -

2. Seiler CA, Balsiger BM, Feodorovici M, Büchler MW. Extensive Intraoperative Lavage. Abdominal Sepsis: International meeting, September 7-9, 1995, Berne, Switzerland

3. Büchler MW, Feodorovici M, Balsiger BM. The role of focus elimination: surgery. Abdominal Sepsis: International meeting, September 7-9, 1995, Berne, Switzerland

4. Balsiger BM, Naef M, Sabbioni M, Läderach K, de Marco D, Bürgi U, Sterchi A, Büchler MW. Indication for Vertical Banded Gastroplasty in morbid obesity. Interdisciplinar Meeting of Visceral Surgery, February 8, 1996, Berne, Switzerland

5. Baer HU, Balsiger BM. Technique and Results of Vertical Banded Gastroplasty in morbid obesity. Interdisciplinar Meeting of Visceral Surgery, February 8, 1996, Berne, Switzerland

6. Balsiger BM, Baer HU, Seiler CA, Feodorovici M, Franz S, Büchler MW. Peritonitis: Herdsanierung, ausgedehnte intraoperative Peritoneal-Lavage und direkter Ab- dominalverschluss als Standardtherapie. Swiss association of Surgery: 83 annual congress, June 6-8, 1996, Geneva, Switzerland

7. Naef M, Balsiger BM, Baer HU, Sabbioni M, DeMarco D, Bürgi U, Sterchi A, Büchler MW. Vertical banded Gastroplasty nach Mason zur chirurgischen Therapie morbider Adipositas. Eine prospektive klinische Studie. German society of research in obesity: 12 annual meeting, October 10 - 12, Wurzburg, Germany

8. Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Adrenergic denervation hypersensitivity in the ileal smooth muscle after small bowel transplantation in rats. Minnesota Surgical Society Fall Meeting, November 1, 1996, Minneapolis, USA

9. Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. Should staging laparascopy in pancreatic cancer be aimed at optimizing palliation, rather than increasing resectability rate? Minnesota Surgical Society Spring Meeting, May 2, 1997, Minneapolis, USA

10. Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Inhibitory neural function in ileal circular smooth muscle after rat small bowel transplantation: Nitric oxide has no role. American Gastroenterological Association and American Association for the Study of Liver Diseases, May 11 - 14, 1997, Washington D.C. USA

11. Shibata C, Balsiger BM, Sarr MG. The extrinsic denervation of small bowel transplantation induces adrenergic hypersensitivity in ileal but not jejunal smooth muscle - at least one interneuron site away from the adrenergic synapse. American Gastroenterological Association and American Association for the Study of Liver Diseases, May 11 - 14, 1997, Washington

- 16 -

D.C. USA

12. Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Differing adaptive responses of ileal and jejunal smooth muscle to denervation after small bowel transplantation. Society for Surgery of the Alimentary Tract, Annual meeting May 11 - 14, 1997, Washington D.C. USA

13. Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. Should staging laparascopy in pancreatic cancer be aimed at optimizing palliation rather than increasing resectability rate? Pancreas Club, May 11, 1997, Washington DC, USA

14. Balsiger BM, Othani N, Sarr MG. The role of nitric oxide in rat jejunal longitudinal smooth muscle. Gut Hormone Symposium, July 25 - July 28, 1997, Florissant, Colorado, USA

15. Othani N, Balsiger BM, Sarr MG. Technique of studying gut smooth muscle activity in vitro. Gut Hormone Symposium, July 25 - 28, 1997, Florissant, Colorado, USA

16. Balsiger BM, Shibata C, Sarr MG. The extrinsic denervation of small bowel transplantation (SBT) induces adrenergic hypersensitivity in ileal but not jejunal smooth muscle - at least one interneuron site away from the adrenergic synapse. Minnesota Surgical Society Fall Meeting, September 19, 1997, Duluth, Minnesota, USA

17. Balsiger BM, Othani N, Anding WJ, Duenes JA, Sarr MG. Nitric oxide (NO) inhibits rat jejunal longitudinal smooth muscle, but is not major mediator of non-adrenergic non-cholinergic (NANC) inhibition. Minnesota Surgical Society Fall Meeting, September 19, 1997, Duluth, Minnesota, USA

18. Balsiger BM, Othani N, Sarr MG. The role of nitric oxide in rat jejunal longitudinal smooth muscle. Midwest Motility Society Meeting, October 2, 1997, Prairie Du Chien, Wisconsin, USA

19. Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. Optimizacion de paliacion en cancer de pancreas mediante laparascopia etapificadora. XXI Mexican National Congress of General Surgery, November 3 - 7, 1997, Acapulco, Mexico

20. Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Inhibitory neural function in ileal circular smooth muscle after rat small bowel transplantation: Nitric oxide has no role. Third annual Balfour surgical research symposium, October 24, 1997, Rochester, Minnesota, USA

21. Shibata C, Balsiger BM, Sarr MG. The extrinsic denervation of small bowel transplantation induces adrenergic hypersensitivity in ileal but not jejunal smooth muscle - at least one interneuron site away from the adrenergic synapse. Third annual Balfour surgical research symposium, October 24, 1997, Rochester, Minnesota, USA

- 17 -

22. Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Differing adaptive responses of ileal and jejunal smooth muscle to denervation after small bowel transplantation. Third annual Balfour surgical research symposium, October 24, 1997, Rochester, Minnesota, USA

23. Balsiger BM, Othani N, Anding WJ, Duenes JA, Sarr MG. Nitric oxide (NO) and non-adrenergic non-cholinergic (NANC) inhibition in longitudinal smooth muscle of rat jejunum. 40th Annual University Surgical Residents’ Conference, February 14, 1998, Milwaukee, Wisconsin, USA

24. Balsiger BM, Ohtani N, Shibata C, Murr MM, Anding WJ, Duenes JA, Sarr MG. Small bowel transplantation (SBT) alters non-adrenergic non-cholinergic (NANC) inhibition in longitudinal smooth muscle of the rat jejunum. Society for Surgery of the Alimentary Tract, Annual meeting May 17 - 20, 1998, New Orleans, USA

25. Balsiger BM, Ohtani N, Shibata C, Sarr MG. Non-adrenergic non-cholinergic (NANC) inhibition in longitudinal smooth muscle of rat jejunum: minor role of nitric oxide (NO). American Gastroenterological Association and American Association for the Study of Liver Diseases, May 17 - 20, 1998, New Orleans, USA

26. Murr MM, Balsiger BM, Kennedy FP, Sarr MG. Malabsorbtive procedures for severe obesity: comparison of pancreaticobiliary bypass (PBB) and very, very long Roux-en-Y gastric bypass (VVLGB). Society for Surgery of the Alimentary Tract, Annual meeting May 17 - 20, 1998, New Orleans, USA

27. Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. Staging laparascopy for pancreatic cancer should be used to select the best palliation, not to increase resection rate. Society for Surgery of the Alimentary Tract, Annual meeting May 17 - 20, 1998, New Orleans, USA

28. Murr MM, Balsiger BM, Farrugia G, Sarr MG. Role of nitric oxide, VIP and ATP in inhibitory neurotransmission in human jejunum. Association of Academic Surgery, November 21, 1998, Seattle, USA

29. Balsiger BM, Ohtani N, Anding WJ, Duenes JA, Sarr MG. Chronic lack of extrinsic neural input increases nitric oxide (NO) independent inhibition after rat small bowel transplantation (SBT). European Society for Surgical Research, 34th congress, April 22-24, 1999, Bern, Switzerland

30. Balsiger BM, Sarr MG. Roux-en-Y gastric bypass (RYGB) as primary operation for morbid obesity at the Mayo clinic. European Society for Surgical Research, 34th congress, April 22-24, 1999, Bern, Switzerland

31. Balsiger BM, Murr MM, Sarr MG. Roux-en-Y gastric bypass as a remedial operation for gastroesophageal reflux (GER) after vertical banded gastroplasty (VBG). Society for Surgery of the

- 18 -

Alimentary Tract, Annual meeting May 16 - 19, 1999, Orlando, USA

32. Ohtani N, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Small bowel transplantation induces adrenergic denervation-hypersensitivity in ileal longitudinal smooth muscles in rats. Society for Surgery of the Alimentary Tract, Annual meeting May 16 - 19, 1999, Orlando, USA

33. Ohtani N, Balsiger BM, Duenes JA, Sarr MG. Nitric oxide mediates non-adrenergic non-cholinergic (NANC) inhibiton in ileal longitudinal smooth muscle of rats. American Gastroenterological Association and American Association for the Study of Liver Diseases, May 16 - 19, 1999, Orlando, USA

34. Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Extrinsic denervation of canine jejunum causes neuronal adrenergic and muscular cholinergic hypersensitivity. Gastroenterological Association and American Association for the Study of Liver Diseases, May 16 - 19, 1999, Orlando, USA

35. Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Neural inhibition in jejunal circular muscle after small bowel transplantation (SBT): nitric oxide (NO) has no apparent role. Society for Surgery of the Alimentary Tract, Annual meeting May 16 - 19, 1999, Orlando, USA

36. Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Adenosine triphosphate (ATP) inhibits canine jejunal contractions by neuronal release of nitric oxide (NO). Gastroenterological Association and American Association for the Study of Liver Diseases, May 16 - 19, 1999, Orlando, USA

37. Lee JS, Farrugia G, Balsiger BM, Camilleri M. Glibenclamide protection of colonic longitudinal smooth muscle contractile response to hypoxia in rats demaonstrates a physiological role of KATP channels. on longitudinal smooth muscle contractility in rat colon. Gastroenterological Association and American Association for the Study of Liver Diseases, May 16 - 19, 1999, Orlando, USA

38. Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Adrenergic contractile mechanisms adapt after chronic extrinsic denervation of the canine small bowel.: Society for Surgery of the Alimentary Tract, Annual meeting May 22 - 24, 2000, San Diego, USA

39. Balsiger BM, Poggio JL, Mai J, Sarr MG. Ten and more years after Vertical banded gastroplasty as primary operation for morbid obesity. Society for Surgery of the Alimentary Tract, Annual meeting May 22 - 24, 2000, San Diego, USA

40. Balsiger BM, Sarr MG, Duenes JA, Anding WJ. Downregulation of nitric oxide dependent inhibition in rat jejunum one year after small bowel transplantation (SBT). Int Society of Digestive Surgery, Sept 6-9, 2000 Hamburg, Germany

41. Balsiger BM, Seiler R, Rickenbacher A, Müller J, Shaw SG:

- 19 -

Muscular and neuronal-adrenergic receptor mechanisms in rat ileal longitudinal muscle contractility. Society for Surgery of the Alimentary Tract, Annual meeting May 19 - 22, 2002, San Francisco, USA

42. Seiler R, Rickenbacher A, Shaw SG, Balsiger BM: Muscular and neuronal adrenergic receptor mechanisms in rat ileal longitudinal muscle contractility. Day of clinical research, University of Bern, Nov 13, 2002, Bern, Switzerland

43. Seiler R, Rickenbacher A, Müller J, Shaw S.G, Balsiger BM: Role of α and β adrenergic receptor mechanisms in rat jejunal longitudinal muscle contractility. Society for Surgery of the Alimentary Tract, Annual meeting, May 17 - 22, 2003, Orlando, USA

44. Rickenbacher A, Seiler R, Müller J, Shaw S.G, Balsiger BM: Role of β1, β2 and β3 receptor contractile mechanisms in adrenergic hypersensitivity after small bowel transplantation. Society for Surgery of the Alimentary Tract, Annual meeting, May 17 - 22, 2003, Orlando, USA

45. Rickenbacher A, Gallagher SF, Yang J, Balsiger BM, Gower WR, Norman JG, Murr MM: Acute pancreatitis induces ileus by upregulating TNF and Nitric Oxide in the small intestine. Society for Surgery of the Alimentary Tract, Annual meeting, May 17 - 22, 2003, Orlando, USA

46. Haefliger Simon, Seiler R, Rickenbacher A, Shaw SG, Balsiger BM: Differential role of nitric oxide in longitudinal and circular muscle of the rat colon. Society for Surgery of the Alimentary Tract, Annual meeting, May 14 - 18, 2005, Chicago, USA

47. Apparent heterogeneity in splanchnic vascular response to norepinephrine during sepsis. J Gorasi, V Krejci, L Hiltebrand, S Brand, H Bracht, B Balsiger, J Takala, S Jakob. 27th International Symposium on Intensive Care and Emergency Medicine. Poster presentation. Brussels, Belgium. March 27-30, 2007

48. Apparent heterogenity in splachnic vascular response to norepinephrine during sepsis. J Gorrasi., LE Bruegger, S Brandt, H Bracht, B Balsiger, J Takala, SM Jakob. 3rd Swiss Symposium in Experimental Surgery. Bern, January 19, 2007

49. Hepatosplanchnic blood flow distribution and in vitro vascular reactivity during hypoxia and cardiac tamponade. José Gorrasi, Francesca Porta, Jukka Takala1, Bruno Balsiger, Sebastian Brandt, Lukas Bruegger, Hendrik Bracht, Stephan M. Jakob. Submitted to the European Congress of Intensive Care Medicine. Berlin, 2007

Video presentations

1. Balsiger BM, Baer HU, Büchler MW. Vertical Banded Gastroplasty. Interdisciplinar Meeting of Visceral Surgery, February 8, 1996, Berne, Switzerland

- 20 -

2. Luque-de Leon E, Balsiger BM, Sarr MG. Transeccion y derivacion gastrica vertical en y- Roux en el tratamiento de la obesidad morbida. XXI Mexican National Congress of General Surgery, November 3 - 7, 1997, Acapulco, Mexico

Unpublished work

1. Balsiger BM. History of Social Work in the Swiss Cancer Society. Thesis, July 26 1993, Prof. Dr. med. U. Boschung, Institute of medical History, Universitiy of Berne

Invited talks

• 24.03.2014 Berner Bildungszentrum Pflege – Proktoskopieverfahren

• 21.08.2015 Berner Bildungszentrum Pflege - Proktoskopieverfahren

• 13.09.2016 Berner Tumorabend– Diagnose: Darmkrebs

• 13.12.16 GI update QUALITÄTSZIRKEL

• 24.01.2017 Berner Tumorabend im Wallis

• 28.02.2017 Berner Bildungszentrum Pflege - Proktoskopieverfahren

• 07.11.2017 ABC Aerztenetzwerk – Schwer verdaulich

• 09.11.2017 Vorlesung 2. Semester-Studenten Thema: "klinische und endoskopische Aspekte des Gastrointestinaltraktes"

• 09.01.2018 Berner Tumorabend– Diagnose: Darmkrebs

• 20. 02.2018 Landfrauenverein Meikirch – Der Darm – ein hochkomplexes und wunderbares Organ

• 21.-22.06.2018 KMH-Kongress Bittersüss Luzern

• 17.08.2018 Berner Bildungszentrum Pflege - Proktoskopieverfahren

• 21.08.2018 Berner Tumorabend im Wallis

• 28.11.2018 Vorlesung Medizin zu klinische Aspekte des GIT 2018

• Teilnahme an diversen Advisory Boards