curriculum vitae...curriculum vitae name: john anthony vanchiere, m.d., ph.d. work address and...

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Curriculum Vitae Name: John Anthony Vanchiere, M.D., Ph.D. Work Address and phone: 1501 Kings Highway, #5-303 Section of Pediatric Infectious Diseases LSU Health Sciences Center - Shreveport Shreveport, LA 71130 318-675-6081 – phone 318-675-6059 - fax Home Address and phone: 6409 Birnamwood Road Shreveport, LA 71106 318-865-4860 - phone Marital Status: Married, five daughters and one son Date and Place of Birth: June 15, 1966; Ft. Wainwright, AK E-mail: [email protected] Current Positions (all at LSU Health Science Center - Shreveport): January 2011-present Vice-Chair for Pediatric Research, Department of Pediatrics July 2009 – present Associate Professor, Department of Pediatrics June 2007-present Chief, Section of Pediatric Infectious Diseases June 2007 – present Member, Center for Molecular and Tumor Virology Academic Employment History: June 2007 – June 2009 Assistant Professor, Department of Pediatrics LSU Health Science Center, Shreveport, LA June 2005 – May 2007 Assistant Professor Department of Molecular Virology and Microbiology Baylor College of Medicine, Houston, TX January 2003- May 2007 Assistant Professor, Department of Pediatrics Section of Infectious Diseases Baylor College of Medicine, Houston, TX Post-Doctoral Training: August 1999 - December 2002 Pediatric Infectious Diseases Fellow Post-Doctoral Fellow in Molecular Virology Baylor College of Medicine, Houston, TX June 1996 – July 1999 General Pediatrics Resident Baylor College of Medicine/Texas Children's Hospital Houston, Texas 77030

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Page 1: Curriculum Vitae...Curriculum Vitae Name: John Anthony Vanchiere, M.D., Ph.D. Work Address and phone: 1501 Kings Highway, #5-303 Section of Pediatric Infectious Diseases LSU Health

Curriculum Vitae

Name: John Anthony Vanchiere, M.D., Ph.D.

Work Address and phone: 1501 Kings Highway, #5-303 Section of Pediatric Infectious Diseases LSU Health Sciences Center - Shreveport Shreveport, LA 71130 318-675-6081 – phone 318-675-6059 - fax

Home Address and phone: 6409 Birnamwood Road Shreveport, LA 71106 318-865-4860 - phone

Marital Status: Married, five daughters and one son

Date and Place of Birth: June 15, 1966; Ft. Wainwright, AK

E-mail: [email protected]

Current Positions (all at LSU Health Science Center - Shreveport):

January 2011-present Vice-Chair for Pediatric Research, Department of Pediatrics

July 2009 – present Associate Professor, Department of Pediatrics

June 2007-present Chief, Section of Pediatric Infectious Diseases

June 2007 – present Member, Center for Molecular and Tumor Virology

Academic Employment History:

June 2007 – June 2009 Assistant Professor, Department of Pediatrics LSU Health Science Center, Shreveport, LA

June 2005 – May 2007 Assistant Professor Department of Molecular Virology and Microbiology Baylor College of Medicine, Houston, TX January 2003- May 2007 Assistant Professor, Department of Pediatrics Section of Infectious Diseases Baylor College of Medicine, Houston, TX

Post-Doctoral Training:

August 1999 - December 2002 Pediatric Infectious Diseases Fellow Post-Doctoral Fellow in Molecular Virology

Baylor College of Medicine, Houston, TX

June 1996 – July 1999 General Pediatrics Resident Baylor College of Medicine/Texas Children's Hospital Houston, Texas 77030

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Education: 1988-1996 M.D., Medical Scientist Training Program

Emory University School of Medicine Atlanta, Georgia 30322

1988-1996 Ph.D., Neuroscience Emory University, Graduate School of Arts and Sciences Atlanta, Georgia 30322

1984-1988 B.S., Physics with Honors, Cum Laude B.S., Chemistry Tulane University New Orleans, Louisiana 70118

1980-1984 Diploma with Academic Distinction St. Louis Catholic High School Lake Charles, Louisiana 70601

Research Training: 1999-2003 Polyomavirus excretion and infection in immune-compromised children and

children with renal diseases. Mentor: Janet S. Butel, Ph.D. Baylor College of Medicine, Houston, Texas

1999-2003 Vitamin A Supplementation in HIV-infected Children in Romania: a Placebo-Controlled Clinical Trial. Mentor: Mark W. Kline, M.D. Baylor International Pediatric AIDS Initiative Baylor College of Medicine, Houston, Texas

1991-1995 Molecular Analysis of the Nucleoprotein, Phosphoprotein, and Matrix Genes of the Hamster Neurotropic Strain of Measles Virus Mentor: William J. Bellini, PhD Centers for Disease Control and Prevention, Atlanta, Georgia.

1987-1988 Optimization of 117m-Sn Production using the Szilard-Chalmers Process Mentor: Leonard F. Mausner, PhD Brookhaven National Laboratory, Upton, New York.

Training Grants and Fellowships: Woodruff Scholar in Medicine, Emory University School of Medicine, 1988-1996. Medical Student Research Grant from the Southern Medical Association, July 1992-June 1993. Investigator-Initiated Grant from Pharmavite, Inc. $40,000, January 2000-May 2002. Secure the Future Fellow in Pediatric HIV Care, Gaborone, Botswana, June-July 2000. Pediatric Infectious Diseases Society Fellowship, July 2000-June2002. NIH Pediatric Medical Research Loan Repayment Program, 2002-2004, 2004-2006.

Honors and Special Recognition: Deans' Honors Scholar, Tulane University College of Arts and Sciences, 1984-1988. National Merit Scholarship, Fall 1984-Spring 1988.

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NCR Centennial Scholarship, Fall 1984-Spring 1988. Science and Engineering Research Semester (Dept of Energy), Fall 1987, Brookhaven

National Laboratory, Upton, NY. Sigma Xi Award for Undergraduate Research, Tulane University, May 1988. Daniel Stanley Elliott Award for Excellence in Physics, Tulane University, May 1988. Participant in the Complex Systems Summer School. Santa Fe Institute, Santa Fe, NM

Summer 1989. Vice-President of Student Government Association, Emory University, 1990-1991. Henry Taub Outstanding Young Investigator Award, Baylor College of Medicine, 2002. Distinguished Lecturer, American Society for Microbiology, 2013-2015. Academic Service BCM Faculty Research & Fellowship Support Committee, 2006-2007 LSUHSC-S Antibiotic Committee, 2008-2013 LSUHSC-S Intramural Grant Review Committee, 2009-2013 LSUHSC-S Institutional Review Board for Human Subject Research Member, 2009-2010, 2012-2013 Vice-Chair, 2010-2012 LSUHSC-S Conflict of Interest Committee, 2010-2013 LSUHSC-S Institutional Animal Care and Use Committee, 2013-2015 LSUHSC-S Department of Pediatrics Residency Education Committee, 2012-present LSUHSC-S Department of Pediatrics Medical Student Curriculum Committee, 2012-present Academic Mentorship: HHMI Mentor for Roger K. Nicome, M.D., 2003-2004 Dissertation Committee of Niraj C. Patel, M.D., 2005-2007 Masters Degree Research Director for Julie Moran, 2006-2007 General Pediatrics Residents: Meena Merti, M.D., 2005-2006 Rohit Gupta, M.D., 2008-2010 Michael Henry, M.D., 2010-2013 CELLULAR Students: Marcie McMahon, 2010-2011 Payton Bannon, 2011-2012 SMART Students: Katie Vanchiere, 2010-2011 Lara Caraway, 2011-2012 Heather Dotting, 2011-2012 Sarah Brantley, 2012-2013 LBRN Students: Lara Crawford, 2013 Scientific Reviews for Professional Journals: Journal of Pediatric Infectious Diseases Journal of the Acquired Immune Deficiency Syndrome Pediatrics Virus Research Journal of Pediatrics Clinical Therapeutics Journal of Infectious Diseases Folia Microbiologica

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Professional Affiliations: American Academy of Pediatrics Louisiana Chapter of the American Academy of Pediatrics

- Executive Committee, Member-at-Large (2007-2011) - Treasurer (2011-2013) - Research Committee, Chairman (2009-2011)

Pediatric Infectious Diseases Society - Research Affairs Committee, Member (2012-2015)

Infectious Disease Society of America American Society for Virology American Society of Microbiology Community Involvement: -Diocesan AIDS Ministry of Catholic Charities, Member of the Speakers Bureau (1999-2005) -Helping Hands Medical Mission, Regional Coordinator for Houston area (2003-2007) -St. Thomas More Catholic Church, Director of the Parish Mission Project (2003-2007) -Medical Director, Helping Hands Medical Missions, Sonsonate, El Salvador (2003-2007) -Executive Board Member, Northwest Louisiana Interfaith Pharmacy (2011-present) -Medical Consultant and Lecturer, Community Focus on Adolescent Sexual Health (Spring 2012) Journal Articles (Peer-reviewed Scientific Research):

1. Rota, P.A., Bloom, A.E, Vanchiere, J.A., and Bellini, W.J. (1994) Evolution of the Nucleoprotein and Matrix Genes of Wild-Type Strains of Measles Virus Isolated from Recent Epidemics. Virology, 198, 724-730.

2. Hummel, K.B., Vanchiere, J.A., and Bellini, W.J. (1994) Restriction of Fusion Protein mRNA as a Mechanism of Measles Virus Persistence. Virology, 202, 665-672.

3. Vanchiere, J.A., Bellini, W.J., and Moyer, S.A. (1995) Hypermutation of the Phosphoprotein and Altered mRNA Editing in the Hamster Neurotropic Strain of Measles Virus. Virology, 207, 555-561.

4. Vanchiere, J.A., White, Z.S., and Butel, J.S. (2005) Detection of BK virus and Simian Virus 40 in the Urine of Healthy Children. Journal of Medical Virology, 75(3), 447-454.

5. Vanchiere, J.A., Nicome, R.K., Greer, J.M., Demmler, G.J., and Butel, J.S. (2005) Frequent Detection of Polyomaviruses in Stool Samples from Hospitalized Children. Journal of Infectious Diseases, 192, 658-664.

6. Vanchiere, J.A., Abudayyeh, S., Copeland, C.M., Lu, L.B., Graham, D.Y., and Butel, J.S. (2009) Polyomavirus Shedding in the Stool of Healthy Adults. Journal of Clinical Microbiology, August 2009, 2388-2391.

7. Broekema, N.M., Abend, J.R., Bennett, S.M., Butel, J.S., Vanchiere, J.A., and Imperiale, M.J. (2010) A system for the analysis of BKV non-coding control regions: application to clinical isolates from an HI/AIDS patient. Virology, 407(2), 368-373.

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8. Patra, K.P., Vanchiere, J.A., Bocchini, Jr., J.A. (2011) Adherence to CLSI Recommendations for Testing of Staphylococcus aureus isolates in Louisiana Hospitals: Report of a Clinical Failure and Results of a Questionnaire Study. Journal of Clinical Microbiology, 49(8), 3019-20.

9. McClure, G.M., Gardner, J.S., Williams, J.T., Copeland, C.M., Frilot, C.F., Groome, L.J. and Vanchiere, J.A. (2012) Dynamics of Pregnancy-Associated Polyomavirus Urinary Excretion: A Prospective Longitudinal Study. Journal of Medical Virology, 84, 1312-1322.

10. Kling, C.L., Wright, A.T., Katz, S.E., McClure, G.B., Gardner, J.S., Williams, J.T., Meinerz, N.M., Garcea, R.L. and Vanchiere, J.A. (2012) Dynamics of Urinary Polyomavirus Shedding in Healthy Adult Women. Journal of Medical Virology, 84, 1459-1463.

11. Kimberlin, D.W., Acosta, E.P., Prichard, M.N., Sánchez, P.J., Ampofo, K., Lang, D., Ashouri, N., Vanchiere, J.A., Abzug, M.J., Abughali, N., Caserta, M.T., Englund, J.A., Sood, S.K., Spigarelli, M.G., Bradley, J.S., Lew, J., Michaels, M.G., Wan, W., Cloud, G., Jester, P., Lakeman, F.D. and Whitley R.J.

for the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group (2013) Oseltamivir Pharmacokinetics, Dosing, and Resistance in Children From Birth to Two Years of Age with Influenza. The Journal of Infectious Diseases, 207, 709-720.

12. Capraro GA, Rambin ED, Vanchiere JA, Bocchini JA, Matthews-Greer JM. (2013) High rates of inducible clindamycin resistance among prenatal group B streptococcal isolates in one northwest Louisiana academic medical center. Journal of Clinical Microbiology, 51(7), ###-###.

13. Vanchiere, J.A., Carillo, B., Morrow, A.L., Jiang, X., Ruiz-Palacios, G.M. and Butel, J.S. (2013) Fecal Polyomavirus Excretion in Infancy. To be submitted to Journal of Infection.

14. Vanchiere, J.A., Copeland, C.M., Lee, C.W., Williams, J.T., Ruiz, J., Williams, L., and Abee, C.R. (2013) Detection of the Squirrel Monkey Polyomavirus in Feces of Captive-bred Squirrel Monkeys (Saimiri boliviensis). To be submitted to Journal of General Virology.

15. Vanchiere, J.A., Copeland, C.M., Williams, J.T., Ruiz, J. and Abee, C.R. (2013) Experimental Infection of Bolivian Squirrel Monkeys (Saimiri boliviensis boliviensis) with Human BK Polyomavirus. For submission to the Journal of Infectious Diseases.

Journal Articles (Peer-reviewed Clinical Papers and Letters):

1. Patel, N.C. and Vanchiere, J.A. (2005) Unilateral Shoulder Swelling in a Preterm Neonate. Seminars in Pediatric Infectious Diseases. 2005 Jan; 16(1), 6, 70-71.

2. Patel, P., Vanchiere, J.A., Conrad, S.A., and Scott, L.K. (2010) Use of therapeutic plasma exchange (TPE) as a rescue therapy in 2009 H1N1 influenza A-associated respiratory failure and hemodynamic shock. Pediatric Critical Care Medicine, June 2010, 10.1097.

3. Vanchiere, J.A. and Casillas, A.M. (2010) Urinary Cytokines in BK Viruria: Letter to the Editor. Transplantation, 90(2), 227.

4. Taba, K.E., Vanchiere, J.A., Kavanaugh, A.S., Lusk, J.D., Smith, M.B. (2011) Successful Treatment of Ophthalmomyiasis Interna Posterior with Ivermectin. Retinal Cases and Brief Reports, 6(1):91-94, Winter 2012.

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5. Patra, K.P., Vanchiere, J.A., Bocchini, J.A., Wu, A.C., Jackson, R.D., Kiel, E.A., and Mello, D. (2012) Sinus of Valsalva aneurysm with Pneumococcal endocarditis. Texas Heart Institute Journal. 39(2):277-80.

6. Sankararaman S, Wells W and Vanchiere J.A. (2012) Case 2: Fever, cough, shortness of breath, jaundice, and hepatomegaly in a teenager. Pediatrics in Review, 33(5):233-9.

Book Chapters:

1. “Human Polyomaviruses and Papillomaviruses.” In Textbook of Pediatric Infectious Diseases, 5th Edition (Feigin, Cherry, Demmler and Kaplan, eds.) Saunders: Philadelphia, 2004.

2. “Polyomaviruses.” In Oski’s Pediatrics: Principles and Practice (4th Edition), (McMillan, DeAngelis, Feigin and Warshaw, eds.) Lippincott: Philadelphia, 2006.

3. “Human Polyomaviruses.” In Textbook of Pediatric Infectious Diseases, 6th Edition (Feigin, Cherry, Demmler and Kaplan, eds.) Saunders: Philadelphia, 2009.

4. “Human Polyomaviruses.” In Red Book: 2009 Report of the Committee on Infectious Diseases. 28th ed. American Academy of Pediatrics: Elk Grove Village, IL, 2009.

5. “Human Polyomaviruses.” In Red Book: 2012 Report of the Committee on Infectious Diseases. 29th ed. American Academy of Pediatrics: Elk Grove Village, IL, 2012.

6. “Adenoviruses.” In Red Book: 2012 Report of the Committee on Infectious Diseases. 29th ed. American Academy of Pediatrics: Elk Grove Village, IL, 2012.

7. “Human Polyomaviruses.” In Feigin and Cherry’s Textbook of Pediatric Infectious Diseases, 7th Edition (Cherry, Harrison, Kaplan, Hotez and Steinbach, eds.) Elsevier: Amsterdam, 2013.

Abstracts:

1. Vanchiere, J.A., Matusa, R.F. and Kline, M.W. The Vitamin A Supplementation Trial (VAST): A Clinical Trial of High-dose Vitamin A in HIV-infected Romanian Children. Poster presentation at the Annual Pediatric Fellows' Day, Baylor College of Medicine, Houston, TX. February 2001.

2. Vanchiere, J.A., Kale, A.S. and Butel, J.S. The Association of Polyomavirus Infection with Nephrotic Syndrome in Children. Poster presentation at the Infectious Diseases Society of America Annual Meeting, San Francisco, CA, October 2001 (with travel grant).

3. Vanchiere, J.A., Kale, A.S., and Butel, J.S. The Association of Polyomavirus Infection with Nephrotic Syndrome in Children. Invited presentation at the St. Jude/PIDS Pediatric Microbial Research Conference, Memphis, TN, February 2002 (with travel grant).

4. Vanchiere, J.A., Kale, A.S., White, Z.S., and Butel, J.S. Association of SV40 with Nephrotic Syndrome in Children. Poster presentation at the International Immune Compromised Host Society meeting, Bergen, Norway, June 2002 (with travel grant).

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5. Vanchiere, J.A., Nicome, R.K., Greer, J.M., Demmler, G.J., and Butel, J.S. Frequent Detection of Polyomaviruses in Stool Samples from Hospitalized Children. Poster Presentation at the St. Jude/PIDS Pediatric Microbial Research Conference, Memphis, TN, February 2005.

6. Vanchiere, J.A., Nicome, R.K., White, Z.S., and Butel, J.S. Diversity of BK Virus Strains in Pediatric Blood, Urine and Stool Samples. Poster Presentation at the Society for Pediatric Research Annual Meeting, Washington, D.C., May 2005.

7. Vanchiere, J.A., Nicome, R.K., Demmler, G.J., and Butel, J.S. Frequent Detection of Polyomaviruses in Stool Samples from Hospitalized Children. Oral Presentation at the 3rd International Conference on Human Polyomaviruses, Providence, RI, October 2005.

8. Vanchiere, J.A., Carrillo, B.B., Morrow, A.L., Jiang, X., Ruiz-Palacios, G.M., and Butel, J.S. BK Virus Excretion in the Stool of Healthy Infants. Poster Presentation at the Society for Pediatric Research Annual Meeting, Toronto, Canada, May 2007.

9. Vanchiere, J.A., Carrillo, B. B., Morrow, A.L., Graham, D.Y., and Butel, J.S. Excretion of Polyomaviruses in the Stool of Healthy Infants and Adults. Oral Presentation at the 4th International Conference on Human Polyomaviruses, Barcelona, Spain, October 2007.

10. Kale, A.S., Vanchiere, J.A., Moran, J.A., Soletsky, E., and Butel, J.S. Polyomavirus Excretion in Pediatric Renal Disease. Poster Presentation at the American Society of Nephrology Annual Meeting, San Francisco, CA, November 2007.

11. Kale, A.S., Vanchiere, J.A., Moran, J.A., Soletsky, E., and Butel, J.S. Polyomavirus Excretion in Pediatric Renal Disease. Poster Presentation at the Society for Pediatric Research Annual Meeting, Honolulu, HI, May 2008.

12. Copeland, C.M., Lee, C.W., Abee, C.R., Williams, L. and Vanchiere, J.A. Detection of the Squirrel Monkey Polyomavirus in Feces from Bolivian and Peruvian Squirrel Monkeys. Poster presentation at the American Society for Virology Annual Meeting, Vancouver, BC, July 2009.

13. Kimberlin, D, Acosta, E, Sanchez, P, Ampofo, K, Vanchiere, J, Englund, J, Sood, S,, Lang, D, Caserta, M, Abzug, M, Abughali, N, Michaels, M, Spigarelli, M, Wan, W, Jester, P, Griffin, J, Whitley, R, for NIAID Collaborative Antiviral Study Group (CASG). Oseltamivir (OST) and OST Carboxylate (CBX) Pharmacokinetics (PK) in Infants: Interim Results from a Multicenter Trial. 47th Annual Meeting of The Infectious Diseases Society of America (IDSA), Philadephia, Pennsylvania, October 31, 2009; Abstract #804.

14. Vanchiere, J.A., Copeland, C.M., Ruiz, J., Butel, J.S., Abee, C.R. Experimental infection of squirrel monkeys (Saimiri boliviensis boliviensis) with human BK virus by intragastric inoculation. Oral presentation at the American Society for Virology annual meeting, Bozeman, MT, July 2010.

15. Vanchiere, J.A., Rambin, E.D., Saucier, A., Bocchini, J.A., Matthews-Greer, J. High Rates of Erythromycin, Clindamycin & Inducible Resistance in GBS Isolated from OB Patients LSUHSC-Shreveport. Oral presentation at the American Society of Microbiology annual meeting, New Orleans, LA, May 2011.

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16. Wiltrakis SM, Cloud GA, Whitley RJ, Sánchez PJ, Ampofo K, Lang D, Ashouri N, Vanchiere JA, Abzug MJ, Abughali N, Caserta MT, Englund JA, Sood SK, Spigarelli MG, Bradley JS, Lew J, Michaels MG, Jester PM, Kimberlin DW. Predictors of Influenza Disease Severity and Resolution in Infants: Results of a National Collaborative Trial. Society for Pediatric Research (SPR), Boston, Massachusetts, April 28, 2012; Abstract #752603. 17. Vanchiere, J.A., McClure, G.B., Rogers, D.L., Nehete, P.N., Ruiz, J.C., McArthur, M.J., Baze, W.B., and Abee, C.R. Development of a nonhuman primate model of polyomavirus disease in Bolivian squirrel monkeys. Oral Presentation at the 5th International Conference on Polyomaviruses and Human Diseases: Basic and Clinical Perspectives. Stresa, Italy, May 9-11, 2013.

18. Reisman, L., Habib, S., Latiolais, L.S., McClure, G.B., Vanchiere, J.A. Treatment of BK Virus Nephropathy after Kidney Transplantation in a Young Child: Elimination of Viremia and Preservation of Function by Treatment with CMX001. Poster Presentation at the 7th Congress of the International Pediatric Transplantation Association. Warsaw, Poland, July 2013.

Invited Lectures:

“Molecular Diagnostics in Immune Compromised Hosts: Focus on BK virus and HHV-6” Children’s Oncology Group Meeting, Washington, D.C., May 2004.

“Human Polyomaviruses: Benign Companions or Hidden Foes?” Pediatric Grand Rounds, Baylor College of Medicine and Texas Children’s Hospital, November 2004.

“Viral Persistence: Surveillance of the Iceberg from Its Surface” Society for Pediatric Research Meeting, PIDS Symposium: “Virus-Host Interactions: Mechanisms Underlying Persistent Viral Infections,” (Co-organizers: J.A. Vanchiere and K. Alexander) May 2005.

“West Nile Virus: When should you worry?” and “Persistent Virus Infections: A Rogue’s gallery of Foes and Opportunists” Acute Care Pediatrics for the Primary Care Provider Conference, Hilton Head, S.C., June 2005.

“Neonatal HSV Infection: Don’t get burned” Pediatrics Grand Rounds at LSU Medical School, Children’s Hospital of New Orleans, July 2005.

“Update on West Nile Virus” Pediatric Postgraduate Symposium at Baylor College of Medicine, Houston, TX, March 2006.

“BK Virus in Pediatric Transplant Recipients” Pediatric Transplant Symposium at the Texas Transplant Institute in San Antonio, TX, April 2006.

“Human Polyomaviruses: Ubiquitous and Emerging Companions” Pediatric Grand Rounds at University of Texas Medical School in Houston, TX, June 2006.

“Molecular Diagnostics in Immune Compromised Hosts” Symposium Presentation at the College of American Pathologist’s Annual Meeting, San Diego, CA, September 2006.

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“Human Polyomaviruses: Ubiquitous and Emerging Companions” Pediatric Grand Rounds at Driscoll Children’s Hospital, Corpus Christi, TX, December 2006.

“Human Polyomaviruses: Ubiquitous, Oncogenic and Still Misunderstood” Grand Rounds Presentation at the Feist-Weiller Cancer Center of LSUHSC-Shreveport, LA, October 2007.

“Antibiotic Stewardship 101: Vancomycin Use in Pediatric Patients” Pediatric Grand Rounds at LSU Health Sciences Center-Shreveport, LA, January 2008.

“Development of a non-human primate model of BK virus infection and disease” Visiting Professor Lecture at M.D. Anderson Cancer Center, Bastrop, TX, March 2009

“Human Polyomaviruses: Ubiquitous, Oncogenic and Still Misunderstood” Grand Rounds Presentation at Cook Children’s Hospital, Fort Worth, TX, March 2009.

“CIVIC 2009: A school-based initiative for influenza vaccination in Caddo Parish” Invited speaker at the Louisiana School Nurses Organization Annual Meeting, Gonzales, LA, April 2009.

“Nothing to Sneeze about: the importance of newly recognized respiratory viruses” Practical Pediatrics CME course presentation, LSUHSC-S, Shreveport, LA, December 2009.

“Diagnosis and Management of Clostridium difficile infection in Children” Pediatric Grand Rounds at Our Lady of the Lake Hospital, Baton Rouge, LA, November 2010.

“Pediatric Healthcare for Children in Louisiana: Where the heck are we going?” Practical Pediatrics CME course presentation, LSUHSC-S, Shreveport, LA, December 2010.

“Pediatric Healthcare for Children in Louisiana” Presentation with Dr. Stewart Gordon, President of the Louisiana Chapter of the American Academy of Pediatrics, to the Baton Rouge Press Club, February 2011.

“Cytomegalovirus and BK virus after kidney transplantation.” Nephrology Grand Rounds at LSUHSC-S, Shreveport, LA, June 2011.

Sexually-transmitted Infections in the School-aged Population: Strategies to Reverse the Epidemic.” Presentation at the Louisiana School-Based Health Center Annual Conference, Baton Rouge, LA April 2012.

“Primary Prevention of Smoking in Youth and Adolescents.” Presentation and Roundtable Discussion at Our Lady of the Lake Hospital, Baton Rouge, LA, April 2012.

“Sexually transmitted infections in adolescence.” Team presentation at Woodlawn High School, Shreveport, LA to ROTC classes, May 2012.

“Molecular Studies of Endemic Viruses in Neotropical Primates: Clues and Conundrums in Evolutionary Biology.” Invited Speaker at the 12th Congress of the Latin American Association for Biological Anthropology, San Jose, Costa Rica, November 2012.

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“Potpourri of Infectious Diseases 2013” Invited speaker with Joseph A. Bocchini, Jr., M.D., Presentation to the Louisiana Association of School-Based Health Clinics Annual Conference, Marksville, LA, April 9-10, 2013. “BK Virus in Pediatric Transplantation: The Basics” Symposium Speaker at the Society for Pediatric Research Annual Meeting, Washington, D.C., May 5, 2013.

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Current/Recent Research Grants and Contracts:

1) “Immune Correlates of BK Virus Reactivation and Persistence in Pregnancy” NIH/NCRR - NIH Center Grant P20RR018724 Center for Molecular and Tumor Virology May 2008-April 2013 Total Cost: $9,704,477.00 Vanchiere = Sub-Principal Investigator: 50% effort, $149,000 per year (reduced by 20% in year 4)

2) “Reactivation of Endemic Squirrel Monkey Viruses during Short-term Immune Suppression”

Cattlemen for Cancer Research Grant, M.D. Anderson Cancer Center October 1, 2010 – September 30, 2011 Total cost: $40,000 Vanchiere = Co-investigator with Dr. Pramod Nehete at MDACC

3) “Infection of Bolivian Squirrel Monkeys with Human JC Polyomavirus” Scientific Research Agreement with Inhibikase Therapeutics, LLC April 2011 – March 2012 Total cost: $127,000 Vanchiere = Principal Investigator

4) “Reactivation of Endemic Squirrel Monkey Viruses during Rituximab-induced Immune Suppression” Cattlemen for Cancer Research Grant, M.D. Anderson Cancer Center June 1, 2012 – May 30, 2013 Total cost: $40,000 Vanchiere = Co-investigator with Dr. Pramod Nehete at MDACC

5) “Single-dose Pharmacokinetic study of Ceftaroline in Pediatric Patients”

Clinical Trial Contract with Cerexa, Inc. March 2011 – February 2012 Vanchiere = Site Principal Investigator

6) “Expanded Access Protocol for Use of CMX001 in Patients with Life-threatening dsDNA Virus

infections (Protocol 350)” Clinical Trial Contract with Chimerix, Inc. June 2011 – May 2013 Vanchiere = Site Principal Investigator

7) “A Phase III Randomized, Partially Double-Blind, Active-Comparator-Controlled, Lot-to-Lot

Consistency Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 4, and 6 Months Concomitantly with Prevnar 13™ and RotaTeqTM” Clinical Trial Contract with Merck + ICON June 2011 – May 2014 Vanchiere = Site Principal Investigator

8) Targeted Clinical Research to Address Select Viral Infections RFP # BAA NIAID-DMID-NIHAI2010101 Principal Investigator = Richard Whitley, M.D., University of Alabama at Birmingham Funded October 2011 Study Period: February 2012 – August 2015

– Preemptive Antiviral Therapy in Infants exposed to Maternal HSV Shedding at Delivery – Investigation of CMX-001 in Infants with Neonatal HSV Disease – Pharmacokinetic, Pharmacodynamic and Resistance Evaluation of IV Gancyclovir

Vanchiere = Site Principal Investigator at LSUHSC-S

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Vanchiere/May 2013

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9) Genotyping of BKV Strains from Clinical Trials of CMX001

Scientific Research Agreement with Chimerix, Inc. September 2011 – August 2014 Vanchiere = Principal Investigator

10) Clinical Trial Contract with Glaxo-Smith-Kline, Inc.; “A Phase IIIA, observer-blind, randomized

study to evaluate non-inferiority of a second dose of GSK Biologicals’ measles-mumps-rubella vaccine vs. a second dose of Merck & Co., Inc.’s MMR vaccine when administered with and without diphtheria, tetanus, acellular pertussis and inactivated polio (DTaP-IPV) vaccine and varicella vaccine to healthy children four to six years of age. 115158 (MMR-158). June 2012 – August 2014; Vanchiere-Site Principal Investigator; estimated $120,000

11) “Endemic Squirrel Monkey Virus and BK Virus Reactivation during Prolonged Immune Suppression” Cattlemen for Cancer Research Grant, M.D. Anderson Cancer Center January 2012 – June 2013 Total cost: $40,000 Vanchiere = Co-investigator with Dr. Pramod Nehete at MDACC

12) Clinical Trial Contract with Cerexa, Inc.; “A Multicenter, Randomized, Observer-Blinded, Active-Controlled Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of Ceftaroline Versus Comparator in Pediatric Subjects With Acute Bacterial Skin and Skin Structure Infections (P903-23) May 2012 – July 2014; Vanchiere = Site Principal Investigator

Completed Grant and Contracts:

1) “A Pharmacokinetic/Pharmacodynamic and Safety Evaluation of Oseltamivir (Tamiflu) for the Treatment of Children less than 24 Months of Age with Confirmed Influenza Infection” Collaborative Antiviral Study Group (CASG) – NIH/NIAID/DMID CASG#114, DMID#06-0059 Vanchiere = Study Site Principal Investigator: 5% effort

2) “Development of a Non-human Primate Model of BK Virus Infection” LSUHSC-Shreveport Intramural Faculty Grant July 2008-June 2009 Total Cost: $18,058 Vanchiere = Principal Investigator: 10% effort

3) “Excretion of Polyomaviruses in Human Feces”

Baylor College of Medicine Intramural Seed Grant July 2005 – June 2006 Total Cost: $25,000 Vanchiere = Principal Investigator

4) “The Role of Polyomaviruses in Pediatric Renal Disease”

NIH/NIDDK- Mentored Clinical Scientist Development Grant (K-08) DK062090 August 2002 – July 2007 Total Cost: $602,630 Vanchiere = Principal Investigator: 70% effort