cruz, john raymond nr32 ms-neuro
TRANSCRIPT
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degenerative disorder of the central nervoussystem
impairs the sufferer's motor skills and speech
DOPAMINE normally sends signals that help
coordinate your movements- 80 percent or
more of these dopamine-producing cells aredamaged, dead, or otherwise degenerated
usually affects people over the age of 50
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John Michael "Ozzy" Osbourne (born 3 December 1948)is an English singer-songwriter and occasional actor, whosecareer has spanned over 40 years. As of December 2010,Osbourne has sold over 100 million albums worldwide
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People witnessed legendary
metal singer OzzyOsbourne shake, stammer,stutter and shuffle aroundwith a walk that grewincreasingly hunched over
and motor functions thatonly seemed to be gettingworse.
The 56-year-old singer presumed his body
shakes were a result of a lifetime of drug abuse
He complained his tremors were "practically
destroying (his) life".
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Ozzy said he first noticed
the tremor in his early20s and that he's always
stammered a bit when he
gets excited.
But lately, it had worsened and none of the
medication doctors had prescribed for him had
made any difference.
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More and more, he
started to feel like aprisoner in his own body.
"You try and mask it. You
try and walk around
hoping people won't see
your hands shaking," hesaid.
"I've done a fair amount of self-abuse and self-medication for years, but I've got no choice
anymore," he said. "If I drink alcohol or do any
recreational drugs like smoke pot it will
affect the medication I'm taking for this tremor
and it'll probably make it worse.
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Signs and Symptoms
Slow or uncontrolled
movement
Shaky hands Imbalance
Muscle stiffness
Speech problems
Features appeargradually and worsen
over time
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Encourage patient to participate in physical
therapy and an exercise program to improve
coordination and dexterity
Emphasize importance of a daily exerciseprogram.
Instruct patient in postural exercises and
walking techniques to offset shuffling gait and
tendency to lean forward.
Encourage warm baths and showers to help relax
muscles and relieve spasms.
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Instruct patient to
establish a regular bowel
routine with a high fiber
diet and plenty of fluids.Constipation is a problem
due to muscle weakness,
lack of exercise, and drug
effects.
Eat a well-balanced diet.
Nutritional problems
develop from difficulty
chewing and swallowing
and dry mouth from
medications.
Encourage patient to be an active participant in
his/her therapy and in social and recreational
events, as Parkinsonism tends to lead to
withdrawal and depression.
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Avoid frequent change in the environment to
minimize confusion if the memory deficit is very
severe, name boards and signboards by the side
of the rooms and things will be very helpful.
Instruct the patients to speak slowly and clearly,
and to pause and take a keep breath at
appropriate levels.
Patients should not be forced into situations in
which they feel ashamed of their appearance.
Suicidal precautions to be followed, if the patient
exhibits any suicidal ideas.
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GBS is an autoimmune disorder.
the peripheral nerves' myelin sheaths are injured or
degraded, the nerves cannot transmit signals efficiently.
Sometimes it is triggered by an infection, surgery or a
vaccination.
is called a syndrome rather than a disease because it is notclear that a specific disease-causing agent is involved.
can affect people of any age, but it becomes more common
with increasing age.
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Diana Sabine Moussier
(born 12 July 1966)
is a German-born,
Mexican-naturalized
actress who is best
known for her work,
frequently as a
villainess, in
numerousMexicantelenovelas such as
Entre el amor y el
and Rosalinda
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In late 2009, Moussier developedGuillain-Barr syndrome and wasforced to alter her shooting schedule
onMi pecado in order to promote herrecovery.
According to Juan Osorio, theproducer ofMi pecado, Moussier'sillness traveled from her spinal cordto her brain, affecting her ability toremember her lines and causing hersuch pain that doctors were forced toput her under sedation
additionally, he claimed that Moussier might be leftparalyzed as a result of the illness.
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As a result of her worsening health, Moussier
was forced to leave the cast ofMi pecado shortly
before the completion of filming.
Moussier announced in
late November 2009 that
her health was
improving and that shewould not be left
paralyzed, although she
stressed that Guillain-
Barr "is an illness that
takes months [from
which to recover]".
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Although she had
recovered from Guillain-Barr by March 2010, her
health has been further
complicated by a
diagnosis of chronicfatigue syndrome
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Respiratory and GI infections.
Vaccination
Surgery
PregnancyCamila PeraltaMoussier, born on 15 July 2003
Paulo PeraltaMoussier, born on 3 July 2006
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Numbness or tingling in the hands and feet and
occasionally around the mouth and lips.
Muscle weakness on both sides of the body in the
legs, arms, and face. Difficulty speaking, chewing, and swallowing.
Inability to move the eyes.
Back pain.
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Immunotherapy
Given that GBS is an autoimmune disorder,
therapies utilized in the acute management of
the disease involve immunotherapy. Thefollowing discusses the use of plasma exchange
(also known as
Plasmapheresis- plasma exchange
intravenous immunoglobulin (IVIg)
and corticosteroids in the treatment ofGBS.
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PLASMAPHERESIS
therapy resulted in significant improvements in
disability within 4 weeks of treatment, as well as
recovery to full strength within 1 year in anincreased proportion of patients
Plasma exchange is considered a safe and cost-effective treatment for GBS
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IVIg(intravenous immunoglobulin)
IVIg has become the preferred treatment for
severe GBS in recent years, largely due to itsrelative convenience of administration
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Corticosteroid Therapy
Various studies evaluating the use of
corticosteroids for the treatment ofGBS have
failed to demonstrate clinical improvements interms of disability after 4 weeks of treatment.
One theory concerning the lack of efficacy is that
corticosteroid therapy adversely affects the
recovery process ofGBS by inhibiting
macrophage clearance of myelin debris, thushindering the remyelination process and/or
aggravating the damage of denervated muscle
fibers
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Physical Therapyy The goals of the therapy programs are to reduce functional
deficits and to target impairments and disabilitiesresulting from GBS.
Occupational Therapy
y Occupational therapy professionals should be involvedearly in the rehabilitation program to promote upper bodystrengthening, ROM, and activities that aid functional self-care.
Speech Therapyy Speech therapy is aimed at promoting speech and safe
swallowing skills for patients who have significantoropharyngeal weakness with resultant dysphagia anddysarthria
Recreational Therapyy Participation in recreational therapy assists in the
patient's adjustment to disability and improves integrationinto the community.
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Treatment is nonspecific and symptomatic.
Patient must be continuously observed for
adequacy of respiratory effort.
Continuous EKG monitoring. Supportive nursing care measures indicated by
the patient's degree of paralysis.
In several weeks, paralysis will begin to
disappear, usually starting from the head andmoving downward.
Residual effects are rare, but prolonged flaccid
paralysis may lead to muscle atrophy requiring
rehabilitation and physical therapy.
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Avoid giving opioids and
sedatives that may depress
respirations.
Position patient correctly and
provide range-of-motion
exercises.
Provide good body alignment,
range-of-motion exercises, andchange of position to prevent
complications such as
contractures, pressure sores, and
dependent edema.
Ensure adequate nutritionwithout the risk of aspiration.
Encourage physical and
occupational therapy exercises to
help the patient regain strength
during rehabilitation phase.
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