cruz, john raymond nr32 ms-neuro

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    degenerative disorder of the central nervoussystem

    impairs the sufferer's motor skills and speech

    DOPAMINE normally sends signals that help

    coordinate your movements- 80 percent or

    more of these dopamine-producing cells aredamaged, dead, or otherwise degenerated

    usually affects people over the age of 50

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    John Michael "Ozzy" Osbourne (born 3 December 1948)is an English singer-songwriter and occasional actor, whosecareer has spanned over 40 years. As of December 2010,Osbourne has sold over 100 million albums worldwide

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    People witnessed legendary

    metal singer OzzyOsbourne shake, stammer,stutter and shuffle aroundwith a walk that grewincreasingly hunched over

    and motor functions thatonly seemed to be gettingworse.

    The 56-year-old singer presumed his body

    shakes were a result of a lifetime of drug abuse

    He complained his tremors were "practically

    destroying (his) life".

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    Ozzy said he first noticed

    the tremor in his early20s and that he's always

    stammered a bit when he

    gets excited.

    But lately, it had worsened and none of the

    medication doctors had prescribed for him had

    made any difference.

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    More and more, he

    started to feel like aprisoner in his own body.

    "You try and mask it. You

    try and walk around

    hoping people won't see

    your hands shaking," hesaid.

    "I've done a fair amount of self-abuse and self-medication for years, but I've got no choice

    anymore," he said. "If I drink alcohol or do any

    recreational drugs like smoke pot it will

    affect the medication I'm taking for this tremor

    and it'll probably make it worse.

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    Signs and Symptoms

    Slow or uncontrolled

    movement

    Shaky hands Imbalance

    Muscle stiffness

    Speech problems

    Features appeargradually and worsen

    over time

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    Encourage patient to participate in physical

    therapy and an exercise program to improve

    coordination and dexterity

    Emphasize importance of a daily exerciseprogram.

    Instruct patient in postural exercises and

    walking techniques to offset shuffling gait and

    tendency to lean forward.

    Encourage warm baths and showers to help relax

    muscles and relieve spasms.

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    Instruct patient to

    establish a regular bowel

    routine with a high fiber

    diet and plenty of fluids.Constipation is a problem

    due to muscle weakness,

    lack of exercise, and drug

    effects.

    Eat a well-balanced diet.

    Nutritional problems

    develop from difficulty

    chewing and swallowing

    and dry mouth from

    medications.

    Encourage patient to be an active participant in

    his/her therapy and in social and recreational

    events, as Parkinsonism tends to lead to

    withdrawal and depression.

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    Avoid frequent change in the environment to

    minimize confusion if the memory deficit is very

    severe, name boards and signboards by the side

    of the rooms and things will be very helpful.

    Instruct the patients to speak slowly and clearly,

    and to pause and take a keep breath at

    appropriate levels.

    Patients should not be forced into situations in

    which they feel ashamed of their appearance.

    Suicidal precautions to be followed, if the patient

    exhibits any suicidal ideas.

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    GBS is an autoimmune disorder.

    the peripheral nerves' myelin sheaths are injured or

    degraded, the nerves cannot transmit signals efficiently.

    Sometimes it is triggered by an infection, surgery or a

    vaccination.

    is called a syndrome rather than a disease because it is notclear that a specific disease-causing agent is involved.

    can affect people of any age, but it becomes more common

    with increasing age.

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    Diana Sabine Moussier

    (born 12 July 1966)

    is a German-born,

    Mexican-naturalized

    actress who is best

    known for her work,

    frequently as a

    villainess, in

    numerousMexicantelenovelas such as

    Entre el amor y el

    and Rosalinda

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    In late 2009, Moussier developedGuillain-Barr syndrome and wasforced to alter her shooting schedule

    onMi pecado in order to promote herrecovery.

    According to Juan Osorio, theproducer ofMi pecado, Moussier'sillness traveled from her spinal cordto her brain, affecting her ability toremember her lines and causing hersuch pain that doctors were forced toput her under sedation

    additionally, he claimed that Moussier might be leftparalyzed as a result of the illness.

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    As a result of her worsening health, Moussier

    was forced to leave the cast ofMi pecado shortly

    before the completion of filming.

    Moussier announced in

    late November 2009 that

    her health was

    improving and that shewould not be left

    paralyzed, although she

    stressed that Guillain-

    Barr "is an illness that

    takes months [from

    which to recover]".

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    Although she had

    recovered from Guillain-Barr by March 2010, her

    health has been further

    complicated by a

    diagnosis of chronicfatigue syndrome

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    Respiratory and GI infections.

    Vaccination

    Surgery

    PregnancyCamila PeraltaMoussier, born on 15 July 2003

    Paulo PeraltaMoussier, born on 3 July 2006

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    Numbness or tingling in the hands and feet and

    occasionally around the mouth and lips.

    Muscle weakness on both sides of the body in the

    legs, arms, and face. Difficulty speaking, chewing, and swallowing.

    Inability to move the eyes.

    Back pain.

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    Immunotherapy

    Given that GBS is an autoimmune disorder,

    therapies utilized in the acute management of

    the disease involve immunotherapy. Thefollowing discusses the use of plasma exchange

    (also known as

    Plasmapheresis- plasma exchange

    intravenous immunoglobulin (IVIg)

    and corticosteroids in the treatment ofGBS.

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    PLASMAPHERESIS

    therapy resulted in significant improvements in

    disability within 4 weeks of treatment, as well as

    recovery to full strength within 1 year in anincreased proportion of patients

    Plasma exchange is considered a safe and cost-effective treatment for GBS

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    IVIg(intravenous immunoglobulin)

    IVIg has become the preferred treatment for

    severe GBS in recent years, largely due to itsrelative convenience of administration

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    Corticosteroid Therapy

    Various studies evaluating the use of

    corticosteroids for the treatment ofGBS have

    failed to demonstrate clinical improvements interms of disability after 4 weeks of treatment.

    One theory concerning the lack of efficacy is that

    corticosteroid therapy adversely affects the

    recovery process ofGBS by inhibiting

    macrophage clearance of myelin debris, thushindering the remyelination process and/or

    aggravating the damage of denervated muscle

    fibers

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    Physical Therapyy The goals of the therapy programs are to reduce functional

    deficits and to target impairments and disabilitiesresulting from GBS.

    Occupational Therapy

    y Occupational therapy professionals should be involvedearly in the rehabilitation program to promote upper bodystrengthening, ROM, and activities that aid functional self-care.

    Speech Therapyy Speech therapy is aimed at promoting speech and safe

    swallowing skills for patients who have significantoropharyngeal weakness with resultant dysphagia anddysarthria

    Recreational Therapyy Participation in recreational therapy assists in the

    patient's adjustment to disability and improves integrationinto the community.

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    Treatment is nonspecific and symptomatic.

    Patient must be continuously observed for

    adequacy of respiratory effort.

    Continuous EKG monitoring. Supportive nursing care measures indicated by

    the patient's degree of paralysis.

    In several weeks, paralysis will begin to

    disappear, usually starting from the head andmoving downward.

    Residual effects are rare, but prolonged flaccid

    paralysis may lead to muscle atrophy requiring

    rehabilitation and physical therapy.

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    Avoid giving opioids and

    sedatives that may depress

    respirations.

    Position patient correctly and

    provide range-of-motion

    exercises.

    Provide good body alignment,

    range-of-motion exercises, andchange of position to prevent

    complications such as

    contractures, pressure sores, and

    dependent edema.

    Ensure adequate nutritionwithout the risk of aspiration.

    Encourage physical and

    occupational therapy exercises to

    help the patient regain strength

    during rehabilitation phase.

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