cps lab catalog

LABORATORY SERVICES: AGROCHEMICALS 2015

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�1 Laboratory Services: Agrochemicals 2015

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Laboratory Services: Agrochemicals 2015 �2

Contents About us 3Environmental Fate at CPS 4Product Chemistry at CPS 5Specialty Services 6Instruments 7Expertise 8Appendix: Protocols 9

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Who we are We’re more than a group of scientists. Specializing in environmental fate, structure elucidation, and product chemistry in the agrochemical industry, our team is engaged in the science of your business and the future of the field.

What we do Our team brings timeliness and structure to your studies. We stay at the bleeding edge of the industry through our publications, and by developing new methods like analyzing proteins via LC-MS/MS.

Why we do it Our laboratory was launched with the goal of helping our clients win in the market. No matter the stage of your pipeline, we’re interested in practicing the best science possible while moving your products forward.

Bring us on board. You’ll be glad you did.

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On-target science We’ve kept our laboratory focused during our steady growth, and our carbon-14 and e-fate services are a direct product of this relentless focus on quality science.

The right expertise Our Study Directors and scientists, with over 30 years worth of experience in environmental fate and metabolism, look at your studies as their own. They know the importance of your timelines, and of open and prompt communication.

The right gear Our laboratory is outfitted with the latest instrumentation to ensure that your work—from adsorb/desorb and metabolism to mineralization and structure elucidation—receives the best treatment possible.

14C & Environmental Fate

Study Type Matrix OECD Guidelines

EPA Guidelines

Adsorption/Desorption

Soil/Sediment

106 835.1230

Hydrolysis Water 111 835.2120; 835.2130 (UV/VIS absorption

Photolysis Soil 316 835.2410

Water 834.2210; 835.2240; 830.7050 (UV/VIS absorption

Aerobic/Anaerobic transformation

Soil 307 835.4100; 835.4200

Aquatic sediment

308 835.4300; 835.4400

Aerobic mineralization

Surface water

309 835.3190

Analytical services at a glance

Study Type Tests performed

Base Price/Rate

Modifyers & Additional Costs

Adsorption/Desorption 3 Soils $

Hydrolysis 1 pH at 3 Temperatures

$

Photolysis Soil/Water $

Aerobic/Anaerobic soil metabolism 3 Soils $

Aerobic/Anaerobic water/sediment metabolism

3 Soils $

Base rates

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People power Our scientists have you covered. Whether developing a method from scratch, identifying metabolites, or performing high-throughput analyses for your residue and product trials, we have the expertise, and the background, that your studies need.

High-tech New tools are always fun, and our lab has them. The newest piece in our facility—an AB Sciex Triple Quad 6500—allows us increased sensitivity for your newest methods and compounds.

Our standard We structured our laboratory according to one simple standard: Focus. We’re focused on providing high quality science while being accessible, even for your large programs. If anything, we shoot for over-communication, and that’s not a bad thing.

Residue and Product Chemistry

To talk about your studies, our rates, and more, contact us today.

tel. +1 610 558 3001 [email protected]

Study Type Guidelines Supported

Residues in rotational crops OECD 504

Multiresidue analysis OPPTS 860.1360

Stability in stored commodities

OECD 506

Field dissipation OPPTS 835.6100

Nature of residues in processed commodities

OECD 507 OPPTS 860.1300

Dislodgeabe foliar residue OPPTS 875.2100

Magnitude of residue (MOR) OPPTS 860.1500

MOR in processed commodities

OECD 508 OPPTS 860.1520

Residue decline OPPTS 860.1500

Crop field trials OECD 509 OPPTS 860.1500

Metabolism in crops OECD 501

Metabolism in rotational crops OECD 502

Metabolism in livestock OECD 503

Residues in livestock OECD 505

Total toxic residue OPPTS 860.1300


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At the core When it comes to ILVs, full or partial method development, even radiovalidations, we’ve got your back. Our analytical and method development chemists are at the ready.

At the forefront New methods to old problems can help shape an industry. With our multiplexed analysis of proteins by LC-MS/MS, we hope to do just that by making your large molecule analyses easier, faster, and cost effective.

Specialty Analytical Services

Development & validation

Independent laboratory validation (ILV)

Method development

Method validation14C Radiovalidation

Biotechnology

Multiplexed protein analysis via LC-MS/MS

ELISA


Study Type Base Price/Rate (plus modifiers)

Modifiers & Additional Costs

Independent Laboratory Validation $

Method Development $

Method Validation $14C Radiovalidation $

Multiplexed protein analysis via LC-MS/MS

$

ELISA $

Base rates

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Instrument

Beta-Ram 5B detector with Waters prep HPLC/UV/Fraction collector

Perkin Elmer Tri-Carb 2910 TR Liquid Scintillation Analyzer

Radiodetection

Instrument

Atlas SunTest CPS+ with Suncool

Harvey Oxidizer

UV-Vis Spectrophotometer

ELISA Tecan Iinfinite F200 microplate reader

Experimental

Instrument

Dionex ASE 350 accelerated solvent extractor

Miilestone Ethos EX microwave extractor

Waters 96-well positive pressure manifold for SPE & SLE extractions

(2) SPEX 2000 Geno-grinder extractors

Sample preparation

Tools of the trade some cool stuff we like to talk about

Instrument Front End

Waters Xevo G2-XS QTOF Acquity I-Class UPLC

AB Sciex 6500 Triple Quad LC-MS/MS

Shimadzu UPLC and CTC PAL autosampler

(2) Sciex API 4000 LC-MS/MS Agilent 1200 HPLC

(2) Agilent 6410B LC-MS/MS (1) Agilent 1290 UPLC(1) Agilent 1200 HPLC

Thermo DSQ-II GC-MS / GC-FID

Agilent 1100 LC-DAD

Chromatography

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Fenn Li, Ph.D.

Our Laboratory Group Leader, Fenn has over 20 years' experience in method development and trace level analysis, and over 8 years’ experience conducting and overseeing environmental fate studies.

More about Fenn Fenn has expertise spanning HPLC, GC, LC-MS/MS, GC/MS, and instruments for detecting radiolabeled compounds (LSC, radioactivity detector, oxidizer, etc).

As a study director and principal investigator for residue and environmental fate studies, Fenn keeps our studies on track and within guideline.

One of our study director superstars, Bridgett is an analytical chemist with experience in small and large molecule separations, environmental fate and metabolism, and protein chemistry.

More about Bridgett Bridgett has worked with LC-MS/MS instruments including accurate mass, and blends this with her knowledge of biotechnology to quantify protiens via LC-MS/MS.

Bridgett also acts as study director and principle investigator for soil and aquatic transformation and other environmental fate studies.

The people just some of the expertise that makes our lab awesome

Bridgett Steele, Ph.D.

To talk about your studies, our expertise, and more, contact us today.

tel. +1 610 558 3001 [email protected]

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We’ve included some sample protocols on the pages that follow for your review.

Enjoy!

Appendix: Protocols

cps lab catalog

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