Course information (extracts from the 2018-19 Handbook)

Courseaimsandlearningoutcomes

Courseaims

Theaimsofthisone-year,full-timeresearchtrainingcourseareasfollows:• togivethestudentexperienceofresearchwork;• toexposethemtoavarietyoflaboratoryenvironmentsandthebalanceofself-

sufficiencyandteamworkneededinaresearcher;• tointroducethemtothebasicskillsofexperimentaldesign,projectmanagement,time

managementetc.neededinresearch;• tofamiliarisethestudentwiththepracticalitiesoflaboratoryresearch,impartingan

understandingofthenatureofbenchresearch,ofrecordkeepinganddatahandlingandofgoodlaboratorypractice;

• tointroducethemtobasicanalyticaltechniquesneededtounderstandandcontextualisetheirresearch;

• tofamiliarisethemwithbasicscientificwritingandpresentationskills.

Thecoursealsoaimsto:• attractstudentsfromawiderangeofbackgroundsintoneurosciencebyprovidinga

taughtmodulewithabasicoverviewofneuroscience;• providestudentsthoroughtraininginneurosciencemethods,dataanalysisandstatistics

techniques;• givestudentsthenecessarybasicbutbroadunderstandingofneurosciencetoprepare

themforfuturePhDstudies;• providestudentswithadequateexperienceinneuroscienceresearchtoenablethemto

makeaninformedchoiceofPhDprojectiftheysowish.

Learningoutcomes

UponsuccessfulcompletionoftheMPhilcourse,studentswillhave:• developedabroadunderstandingofmodernresearchtechniques,andthorough

knowledgeoftheliterature,applicabletoresearchintopicsrelatedtoNeuroscience;• beenexposedtoanumberoftheoreticalapproachestobrainscienceandtrainedin

criticalthinkinginthearea;• acquiredspecificexpertiseinneuroscienceresearchmethodsandstatistics;• demonstratedoriginalityintheapplicationofknowledge,togetherwithapractical

understandingofhowresearchandenquiryareusedtocreateandinterpretknowledgeinthefield;

• acquiredknowledgeofabroadrangeofinterdisciplinaryresearchareasandsupervisorstoinformtheirchoiceofPhDprojectsifapplicable;

• undertakentrainingingenericandtransferableresearchskillsincludingthecriticalevaluationofcurrentresearchandresearchtechniquesandmethodologies.

MPhilProgrammeStructure

TheprogrammeisadministeredfromtheDepartmentofPhysiology,DevelopmentandNeuroscience,butbothtaughtcomponentsandlabrotationsinvolveawiderangeofparticipatingdepartments.

TheMPhilisaone-yearfull-timeprogrammeandinvolvesbothformalteachingandresearch:studentsareintegratedintotheresearchcultureofatleastoneDepartmentbyjoiningaresearchgroup.Inaddition,theytakeresearchtechniquemodulestobroadentheirexperienceofresearchtechniques.TheymayattendtheDepartments'programmeofresearchseminarsandothergraduatecourses,butmostresearchtrainingisprovidedwithinthegroupstructureandoverseenbytheirresearchsupervisors.Informalopportunitiestodevelopresearchskillsalsoexistthroughmentoringbyfellowstudentsandmembersofstaff.

TheMPhilbeginswithaninductionperiodcomprisinggenericcoursesorganisedbytheGraduateSchoolofLifeSciences(includingsafety,scienceethics,keepinglaboratorynotebooksandintellectualproperty),andintroductorylecturesonaspectsofNeurosciencefollowedbymeetingswitheachoftheparticipatingsupervisorsintheirlaboratories.Thesemeetingswillformthebasisofselectionofonemini-project.Inaddition,thestudentswillchoosethreeshorterresearchtrainingmodules,spanningdifferentaspectsofNeuroscience,introducingarangeofproblems,experimentaltechniquesandlaboratoryenvironments.

MPhilResearchProjects

TheMPhilincludesaprojectinalaboratoryofthestudent'schoice,chosenfromprojectsofferedbyCambridgeNeurosciencePrincipalInvestigators- a list is issued to the students when they joinThewriteupfortheprojectisformallyassessedand forms70%oftheoverallmarkforthedegree.

ExtendedEssay

A5,000-wordextendedessay;ThetopicoftheessaymustbeapprovedbytheProgrammeDirectorandwillformthebasisoftheportfoliooflecturesandseminarswhichthestudenttakes.StudentswishingtocontinuetothePhDmayseekapprovaltoreplacetheessaywitharesearchproposalfortheirchosenproject.Thisessayforms25%oftheoverallmarkforthedegree.

ResearchMethodsandStatistics

1 PracticalintroductiontoMATLABProgramming-compulsory

This8-hourintensivecoursefocusesonpracticalhands-onvariablehandlingandprogrammingimplementationratherthanontheory.

Fortimetable,pleaseseeAppendix1andformoreinformationseeAppendix4

2 StatisticalMethodsforBiologists-compulsory

This30-hour‘StatisticsforBiologists’coursewillfocusonpracticalstatistics,teachingyouhowtoperformsimpleanalysesusingthestatisticalpackageR.Thismodulewillbelinkedtoanassessmentthatwillform5%oftheoverallmarkforthedegree.

Fortimetable,pleaseseeAppendix1andformoreinformationseeAppendix4

3 StatisticalMethodsforCognitivePsychologists–optional

This9-hourlecturecoursewillserveasanintroductiontostatisticalmethodsforgraduatestudents.

Fortimetable,pleaseseeAppendix1andformoreinformationseeAppendix4

ThefirstsessionisscheduledforThursday4thOct11:00-12:00andisheldintheLectureTheatre,MRCCognitionandBrainSciencesUnit,UniversityofCambridge,ChaucerRoad.

CambridgeNeurosciencethemedseminars

Studentsreceiveatotalofmorethan20hoursoflectures,seminarsandworkshopsonthefive

mainthemesofCambridgeNeuroscience;DevelopmentalNeuroscience,CellularandMolecular

Neuroscience,CognitiveandBehaviouralNeuroscience,ClinicalandVeterinaryNeuroscience,

SystemsandComputationalNeuroscience.Fortimetable,seeAppendix1.

WorkshopsonNeuroscienceMethods

StudentsmayattendPartIINeuroscienceMethodsworkshops.TheseareorganisedasonelecturepresentationonaThursday3-4pm.Details provided when students join the course.

ResearchTrainingModules

Studentswillchooseaminimumofthreeresearchtrainingmodules,fromachoiceofninemodules.Studentsmaycomplete(andindeedareencouraged)morethantheminimumthreeresearchmodules.

Someofthesemodulesarealreadytimetabledinconjunctionwithothercoursesandotherswillbespecificallyrunforyourgroup.FormoreinformationoneachoftheResearchModulesseeAppendix5.

InterdisciplinaryseminarsandjournalClubs,Seminars

TheCambridgeNeurosciencecommunitycollectivelyhosts~350talksandseminarsperannum.Pleaseseehttp://www.neuroscience.cam.ac.uk/talks/Tosignuptoreceiveemailalertsaboutneuroscienceseminars,ortoaddtalkstothelist,pleasevisithttp://www.talks.cam.ac.ukFormoreinformation,seeAppendix6.

MPhilCourseworkandEvaluation

TheMPhilisassessedinfourways:1. Areportontheresearchproject,approvedorprescribedbytheDegreeCommittee,not

exceeding10,000wordsinlength,includingtables,figurelegends,andappendices,butexcludingbibliography(70%).Submissiondeadline1August2019.

2. A5,000-wordextendedessay;ThetopicoftheessaymustbeapprovedbytheProgrammeDirectorandwillformthebasisoftheportfoliooflecturesandseminarswhichthestudenttakes.StudentswishingtocontinuetothePhDmayseekapprovaltoreplacetheessaywitharesearchproposalfortheirchosenproject.Thisessayforms25%oftheoverallmarkforthedegree.Submissiondeadline1April2019.

3. AnMCQpaperonResearchmethodsandstatisticscriticalappraisal(5%).Separatelyarranged.

4. Anoralexamination,whichwillcoverallofthesubmittedworkabove.Thisoralexaminationformstheoverallmarkforthedegree.TobearrangedforAugust2019.

Thereisnospecificassessmentoftheresearchmodules,butthismayformpartoftheoralexaminationin(4)above.

MPhilProjectReports

Projectreportsshouldbeamaximumof10,000wordsinlength,includingfigurelegendsbutexcludingthebibliography(andwordsinTables).Yourwordcount(excludingthebibliography)mustbegivenonthetitlepage.

Reportsshouldbebrokendowninto:Abstract,Introduction,Methods,Results,DiscussionandReferences.

ResearcherDevelopment

• PersonalSkills(e.g.leadershipandresilience)

• ProfessionalSkills(e.g.presentationskillsandtimemanagement)

• Career-relatedSkills(e.g.writingCVsandinterviewtechnique)

• AcademicSkills(e.g.paperwritingandteaching)

• EntrepreneurialSkills(e.g.commercialawarenessandinnovation)

ResearcherDevelopment(RD)encompassesallofthelearninganddevelopmentthatyoumightwishtoexperienceandacquireduringyourtimeinCambridge.Itisneededtoprovideyouwiththeskillsandexperiencesthatyouneedbothtodayandforthefuture,whateverthatmightbe.

ThestructureforyourRDisprovidedbytheCambridgeResearcherDevelopmentFramework.Thistellsyouaboutthecompetenciesyouneedtogaintomeetthegoalofbecomingaprofessionalresearcher

WithinCambridgetherearemanyprovidersofRDactivities.ThecentralprovisionisprovidedbytheResearcherDevelopmentTeam(www.rdp.cam.ac.uk)andtheGSLSprovidesyouwithaCoreSkillsTrainingProgramme(CSTP)andotherlifescience-specificactivities(www.gradschl.lifesci.cam.ac.uk/GSLSRD).TrainingisalsoavailablefromtheUniversityInformationServices,UniversityLibraryandtheCareers’Service.

TheCSTPisagroupofactivitiesthatyouarestronglyrecommendedtocompleteinyourfirst

AtallstagesoftheProgrammeyoumustadheretotheUniversityandSchoolGuidelinesforassessedwork.TheUniversity’sstatementonplagiarismisbelow.Moreinformationisavailablehere:www.admin.cam.ac.uk/univ/plagiarism/students/

Plagiarism

year.IthasbeendesignedtogetyoustartedinplanningyourRDandprovidingyoutrainingintheareasofpersonaleffectivenessandcommunication.IfyousuccessfullycompletetheCSTPyouwillreceiveacertificatefromtheGSLS.

DepartmentalTrainingOpportunities

Duringtheyear,studentswillbeinvitedtotakepartintrainingopportunities(journalclubs,etc.)intheDepartment(s)orPartnerInstitute(s)wheretheyaredoingtheirprojects.

HealthandSafety

StudentsmustadheretothespecifichealthandsafetyregulationsoftheDepartmentinwhichtheyareworkingateachstageoftheProgramme.InformationonGeneralSafetyinResearchLabsisincludedinAppendix3.StudentsmustattendthecompulsorylecturesintheUniversitySafetycourseinOctober(seeAppendix1).Wealsoencouragestudentstoattendtheoptionalbiologicalsafety,cryogenics,VDUs,pipettes,glassandsharps,andradiationcourses.Coursescanbebookedonline:www.safety.admin.cam.ac.uk/training/graduate-safety-course/current-timetable-venues-and-handouts

Laptops

Studentswillrequirealaptopforsomeofthecompulsorymodulesincludedinthiscourse.Laptopsarenotprovided.

Lectures

Studentsarewelcometoattendundergraduatelecturesinneuroscience.OfparticularinterestistheNSTPart1BNeurobiologycourse:euhttps://www.biology.cam.ac.uk/undergrads/nst/courses/neuro

Appendix1:2018/19StudentTimetables

Introductions,Safety,ResearchMethodsandStatistics(COMPULSORY)Date Time Activity1stOctoberMon 16:00-17:00 WelcometotheMPhilBasicandTranslationalNeuroscience

Venue:SmallMeetingRoom,PhysiologicalLaboratory-Map

2ndOctoberTue 08:45-13:00 TheUniversityGeneralSafetyandChemical/LaboratorySafetyCourse(compulsory)Venue:BabbageLectureTheatre-MapAllstudents–IMPORTANTAttendanceismandatory.Pleasegotohttp://www.safety.admin.cam.ac.uk/training/graduate-safety-course/current-timetable-venues-and-handouts.

3rdOctoberWed Varioustimes(nobookingrequired)

Optionalsafetysessions

TheUniversitySafetyCourseII:Optionalsessions.Venue:MillLaneLectureRooms-MapForfurtherinformationandtimetableseewww.safety.admin.cam.ac.uk/training/graduate-safety-course/current-timetable-venues-and-handouts).https://www.safety.admin.cam.ac.uk/files/day2_prog_oct18.pdf

4thOctober,Thur

5thOctober,Fri

10:00-12:0014:00-16:00

10:00-12:0015:30-17:30

Matlabprogramming,compulsory

PracticalintroductiontoMATLABProgramming

Venue:KennethCraikRoom-CraikMarshallBuildinghttps://www.training.cam.ac.uk/jsss/venue/1897185

Coursedescriptionandprerequisitescanbefound:https://www.training.cam.ac.uk/jsss/event/2511964andhttps://www.psychol.cam.ac.uk/grads/grads/information-for-all-graduate-students-1/pg-prog/programming#section-0

3rd-18thDecember(varioustimes–27hours)

StatisticalMethodsforBiologists–compulsoryVenue:MillLaneMeetingrooms(checkonlinecalendar)StatisticsforBiologiststhatfocusesonpracticalstatistics,teachingyouhowtoperformsimpleanalysesusingthestatisticalpackageR.

Exam:January18th10:00-13:00,Venue:Mill Lane Lecture Theatres – Room 5

SeminarsonthethemesofCambridgeNeuroscience(COMPULSORY)Date,time,location Lecturers ActivityWeekstarting16Oct

Monday8Oct,15:00-16:30

Wed10Oct,10:00-12:00

Wed17Oct,14:00-16:00

Friday19Oct,10:00-12:00

Venue:Smallmeetingroom,PDN

Lecturers:

DrHughRobinson

ProfessorOlePaulsen

ProfessorOlePaulsen

DrDavidParker

CellularandMolecularNeuroscience

• Actionpotentialsandvoltage-gatedionchannels

• Synaptictransmissionandligand-gatedionchannels

• Synapticplasticity,neuro-modulationandGPCRs

• Neuronalnetworks

Weekstarting29October

Monday29Oct,14:00-16:00

Tuesday30Oct,14:00-16:00

Venue:Smallmeetingroom,PDN

Lecturers:

DrMatthiasLandgraf

DrMarcoTripodi

DevelopmentalNeuroscience

Weekstarting12November,

Thur15Nov,10:00-12:00

Monday19Nov,10:00-12:00

Venue:MathsLab

Lecturers

DrStephenEglen(DAMTP)

DrRaphaelRomeroGarcia(Psychiatry)

SystemsandComputationalNeuroscience

WeekstartingTBC

Venue:TBC

DrDavidBelin(Psych)DrPaulaBanca(Psych)DrAmyMilton(Psych)ProfessorAngelaRoberts(Physiology,DevelopmentandNeuroscience)

CognitiveandBehaviouralNeuroscience• BehaviouralControlin

PsychiatricDisorders• Compulsivityand

ImpulsivityinAddiction• Memory• Emotion

WeekstartingTBC

Venue:TBC

ProfessorRogerBarkerProfessorGiovannaMallucci

Workshop:MedicalandVeterinaryNeuroscience

Extract from the 2018-19 Course HandbookExtract from the 2018-19 Course Handbook

Optionalstatisticsseminars

4thOctober,Thu11thOctoberThu18thOctober,Thu

25thOctober,Thu8thNovember,Thu

15thNovember,Thu22ndNovember,Thu

29thNovember,Thu6thDecember,Thu

11:00-12:0011:00-12:0011:00-12:00

11:00-12:0011:00-12:00

11:00-12:0011:00-12:00

11:00-12:0011:00-12:00

StatisticalMethodsforCognitivePsychologists-Optional

ExploratoryDataAnalysisSimpleandmultiplelinearregressionTheGeneralLinearModelandcomplexdesignsincludingAnalysisofCovarianceCategoricalDataAnalysisANOVAofbalancedmulti-factorialdesigns:betweensubjectdesigns,andsinglesubjectstudiesRepeatedmeasuresandmixedmodelANOVAPost-hoctests,multiplecomparisons,contrastsandhandlinginteractionsPoweranalysisLatentvariablemodels:factoranalysisandallthat

Venue:LectureTheatre,MRCCognitionandBrainSciencesUnit,15ChaucerRoad,CambridgeCB27EFmapMoreinformation

Extract from the 2018-19 Course Handbook

Optionalneurobiologylectures

NeurobiologyLectures2018-19Thursday,SaturdayandTuesday,12noon

* Lectureswillbeheldat13:00,(exceptSaturday24thNovemberwhichisat12:00noon)

Venue:AnatomyLectureTheatre

Term Subject Lecs Startdate Lecturer

Mich. ElectricalPropertiesofNeurons 4 4thOct DrSueJones

NeurotransmissionandNeuromodulation 5 13thOct DrPeterEvans

Hearing 3 25thOct DrIanWinter

Vision 6 1stNov DrHughMatthews

OlfactionandTaste 2 15thNov DrHughMatthews

SomatosensationandPain* 4 20thNovDrIanWinter(3)DrEwanStJohnSmith(1)

Lent MotorSystem 8 15thJan DrDavidParker

SensorimotorIntegration 2 2ndFeb DrSteveEdgley

NeuralDetermination 4 7thFeb DrRichardAdams

DevelopmentofNeuralConnections 4 16thFeb DrMatthiasLandgraf

SynapticEfficacy 4 26thFeb Dr.SusannaMierau

MotivationandEmotion 4 7thMar DrAmyMilton

Easter LanguageandtheBrain 2 23rdApr DrMeredithShafto

LearningandMemory 4 27thApr

HigherFunctionsoftheNervousSystem 3 7thMay DrHannahClarke

Appendix4:ResearchMethodsandStatistics

PracticalintroductiontoMATLABProgramming(8hours)CompulsoryDénesSzűcswillrunan8-hourintensivecourseentitled'PracticalintroductiontoMATLABProgramming'.Thecoursefocusesonpracticalhands-onvariablehandlingandprogrammingimplementationratherthanontheory.Thiscourseisintendedforthosewhohaveneverprogrammedbeforeincludingthosewhoonlycall/runMatlabscriptsbutarenotfamiliarwithhowcodeworksandhowmatricesarehandledinMatlab.(Notethatcallingacoupleofscriptsisnot'real'programming.).ItisessentialthatyoubringyourownlaptopwiththelatestversionofMatlab(seewww.mathworks.com)pre-installed.CambridgestudentscandownloadandinstallMatlabfrommathworks.comforfreewiththeirCRSid.Selectandinstallallpackagesavailabletoyou.WewillimmediatelywriteprogrammecodesothebestwaytolearnistouseMatlabduringtheclassfortakingnotesandrunningthecode.ItisadvisablethatyouskimthroughtheexcellentfreeresourceGettingStartedandLanguageFundamentalsThursday4October2018-10.00-12.00and14:00-16:00Friday5October2018-10.00-12.00and15.30-17.30AllsessionswilltakeplaceintheKennethCraikSeminarRoom.Youmustattendallsessions.

StatisticalMethodsforBiologists(27hours)CompulsoryDrMattCastlewillrunthiscourse.Thecourseis10sessionsof2.5-3hourseach.Itisessentialthatyoubringyourownlaptop.Thefirst1hourisaninteractivelectureandtheremainderisessentiallyapracticalsession.StatisticsforBiologiststhatfocusesonpracticalstatistics,teachingyouhowtoperformsimpleanalysesusingthestatisticalpackageR.Thiscoursewilltakeplacefrom3rd-13thDecember.December3rd,4th6th7th10th11th(14:00-17:00oneachday);13thDecember(10:00-13:00and14:00-17:00).Allclasseswilltakeplacein‘17MillLane–MeetingRoomB’exceptDecember6th(17MillLane–MeetingRoomE).Thiscoursewillbefollowedbyanassessment(5%offinalmark)onFridayJanuary18th2019,10:00-13:00(MillLaneLectureTheatres–Room5).Youmustattendallsessions.

StatisticalMethodsforCognitivePsychologists(9hours)Optionalhttp://www.mrc-cbu.cam.ac.uk/seminar-information/statistics-seminars/Thisisacourseplannedwiththeneedsinmindofagraduatestudentstartingtheirstudies.Thepresentationwillbeasfairlyformallectures,eachaimingto:

• outlineaparticularclassofmethods• giveexamplesofitbeingappliedtorealisticsituations• indicatehowtoimplementitusingsoftwareavailableatCBU.

AlltalkswillbegivenbyPeterWatsonoftheMRCCognitionandBrainSciencesUnit.TalkswilltakeplaceonThursdaymorningsfrom11:00-12:00inMichaelmastermfromOctober4th-December6th2018,intheLectureTheatreattheMRCCognitionandBrainSciencesUnit(MRCCBSU),15ChaucerRoad,CambridgeCB27EF.

Appendix5:ResearchTrainingModules(provisionallist)

ResearchModule1:ComputationalNeuroscience(16hours)DrStephenEglen,DepartmentofAppliedMathsandTheoreticalPhysics(February2019)This16-hourcoursewillintroducekeytechniquesincomputationalneuroscience.ThestartingpointistheclassicalmodelofactionpotentialgenerationandpropagationbyHodgkinandHuxley.Afterthisisintroduced,wewillexaminesimplificationsforcomputationalconvenience.Movingfromthesinglecelltonetworksofneuronsallowsustostudyshort-andlong-termmemoryformation.Wethenexplorehowlarge-scalehumanbrainnetworksaregeneratedandanalysed.Inthefinalpartofthecoursewewillexaminenetworkplasticityanddevelopment.

ResearchModule2:QuantitativeAnalysisofNeuroimagingStudiesDrJonSimonsandDrJaneGarrison,DepartmentofPsychology(December2018)Meta-analysisisanincreasinglypopularandusefulmethodforintegratingresearchfindingsacrossnumerousfunctionalneuroimagingstudies.Quantitativemeta-analysescanbeusedtolocalisebrainregionsmostconsistentlyassociatedwithaparticulartypeofbehaviourdespitevariationinparticipants,tasksandscanningprocedures.Studentswilllearnhowtoextractcoordinatesofbrainactivationpatternsfromneuroimagingpapersandusesoftwaretoconductameta-analysisofhumanbrainfunction.

ResearchModule3:NeuralmarkersandmechanismsofimpulsivityandcompulsivityProfessorJeffDalleyandDrBiancaJupp,DepartmentofPsychology(February2019)Impulsiveandcompulsivesymptomsarepresentinmanyneuropsychiatricandneurologicaldisorders(e.g.ADHD,OCD,addiction,PD).Cluestotheaetiologyofimpulsive/compulsivedisordershavebeensignificantlyinformedbytranslationalresearchinclinicalpopulations,heathyhumanvolunteers,andexperimentalanimals,tothepointwherenoveltherapiesarenowbecomingarealisticprospect.StudentswilljointheDalleylaboratorytoworkonthemolecularandbehaviouralmechanismsofimpulsivity/compulsivityinrats,andwillacquiretransferrableskillsinatleasttwooffollowingexperimentaltechniques:(i)theobjectivemeasurementofbehaviourinexperimentalanimals;(ii),localgeneexpressioninthebrain;(iii)analysisofsubpico-molarquantitiesofneurotransmittersinbrainsamples;(iv)interventionalapproachestotargetdefinedneuralcircuitsinthebrain;(v)analysispipelinesforhigh-fieldmagneticresonanceimaging(rsfMRI,voxel-basedmorphometry,spectroscopy,diffusiontensorimaging).

ResearchModule4:LoosePatchClampRecording(20hours)DrHughMatthews&ProfessorChrisHuang,DepartmentofPhysiology,Development&Neuroscience(November2018)In this intensivehands-onpracticalmethods course youwill investigate the voltage and timedependent sodium and potassium conductances of mouse gastrocnemius muscle. You willrecordthe ioniccurrents flowingacrossthemusclemembraneundervoltageclampusingtheloose patch clamp technique. From these records you will be able to study the voltage-dependentgatingofthesodiumandpotassiumconductancesunderlyingtheactionpotential.Youwill also use a computermodel incorporating the Hodgkin-Huxley equations to simulate

someoftheexperimentswhichyouwillcarryout, inorderto improveyourunderstandingofthewayinwhichtheseconductancesdependonmembranepotential.

ResearchModule5:CognitiveElectrophysiology(20hours)DrDenesSzucs,DepartmentofPsychology(DatesTBC)Inabouttwohoursdurationstudentswillattendhands-onpracticalsessions,learnabouthumannon-invasiveelectrophysiologicaldataacquisitionandsetupadummymeasurementsession.Duringtherestoftheprojectstudentswillhaveachancetoworkwithalreadyacquiredhightemporalandspatialresolution(129electrodechannels)electrophysiologicaldatatogainsomedataanalysisexperience.Theacquireddatawillhavebeencollectedinanumericalcognitionexperimentalparadigminadulthumansandoffersinsightsintohownumericalrepresentationsareorganized.Thismoduleisparticularlysuitedtostudentswithstrongprogramming,analyticalandMatlabexperiencebecauseitrequiredadvancedmodellingofthedata.Thisprojectcanbedevelopedfurtherintoafullblownresearchproject."

ResearchModule6:Invertebratemodelsforstudyingneuro-developmentaldisorders(6-8hours)DrJimenaBerniandDrMatthiasLandgraf,DepartmentofZoology(January2019)Thisresearchmoduleisahands-onintroductiontothepowerofinvertebratemodelsystemsforstudyingneurodevelopmentalconditions.YouwillbeworkingwithaDrosophila(fruitfly)modelforstudyingmechanismsunderlyingnetworktuningduringcriticalperiodsandseizures,whichresultwhentuningisdisturbed,leadingtosub-optimallyadjusted,unstablenetworks.Withinafewhourswewillexploreforthefirsttimetheroleofnovelplasticitypathwaysinnetworktuningandseizuresusceptibility;usinggeneticmanipulationswewillaskwhetherseizuresusceptibilityiscompartmentalisedtospecificregionsorneuronalsubsets.Youwillworkwithlarvalandadultstages,observeandquantifyrangesofanimalbehaviourandcarryoutdifferentseizureinductionassays.Overall,thisresearchmodulewillillustratetheadvantagesofusinginvertebratemodelsystemsforfundamentalresearchthatisclinicallyrelevantandoffersopportunitiesfortranslation.

Skills-orientedtrainingopportunitiesattheMRCCBSU(Researchmodules7-9)http://imaging.mrc-cbu.cam.ac.uk/methods/education

DetailswillbeannouncedbeforeindividualeventsviaMRCCBSU"skillstraining"mailinglist,instructionscanbefoundhere:http://imaging.mrc-cbu.cam.ac.uk/methods/education.(NonMRCCBSUpeoplecansubscribebysendingane-mailtoskillstraining-subscribe@mrc-cbu.cam.ac.uk.)

ResearchModule7:IntroductiontoScientificComputingandMatlab(16hours)DrOlafHauk,MRCCognitionandBrainSciencesUnit(October2018)Moreinformation:http://imaging.mrc-cbu.cam.ac.uk/methods/MatlabLecturesScheduleMatlabistheSwissArmyKnifeofdataanalysis:nomatterwhetheryouareanalysingneuroimagingdata,behaviouraldataoryourlatestbankstatements,Matlabcanmakeyoudothingsyouthoughtwereneverpossible.TheseMatlabworkshopsalsoserveasanintroduction

toscientificcomputing,whichwillbeusefulevenifyouaremorelikelytouseR,Pythonetc.inyourwork.Theseworkshopsareaimedatresearcherswithnoorlittlepriorexperiencetoprogramming(inMatlaborotherwise).ItisnotintendedtoprovideafullMatlaborLinuxcourse,butrathersignificantlyfacilitatethefirstfewsteps.ThiscoursewilltakeplaceintheweekcommencingOctober22nd2018(22nd,23rd,24th,26th).SessionswilltakeplaceintheWestWingSeminarRoomandwilltakeapproximately2hours,withanopportunitytopracticeandaskquestionsafterwards.

ResearchModule8:IntroductiontoSignalAnalysisinMatlab(14hours)DrOlafHauk,MRCCognitionandBrainSciencesUnit(November2018)Moreinformation:http://imaging.mrc-cbu.cam.ac.uk/methods/SignalAnalysisMatlabScheduleTheseworkshopsareaimedatbeginners,butsomebasicknowledgeofMatlabisrequired,e.g.atthelevelofourprevious"IntroductiontoMatlabandScientificComputing"workshops(ResearchModule7).ItisnotintendedtoprovideafullMatlaborsignalprocessingcourse,butrathersignificantlyfacilitatethefirstfewsteps.Theseworkshopsprovideabasisforthefollowingworkshopseries"IntroductiontoNeuroimagingMethods"(ResearchModule9).ThiscoursewilltakeplaceintheweekcommencingNovember12th2018(12th,13th,14th16th).SessionswilltakeplaceintheWestWingSeminarRoomandwilltakeapproximately2hours.

ResearchModule9:IntroductiontoNeuroimagingMethods(~40hours)DrOlafHauk,MRCCognitionandBrainSciencesUnit(January2019-February2019)Moreinformation:http://imaging.mrc-cbu.cam.ac.uk/methods/IntroductionNeuroimagingLecturesLecturesandworkshopswilltakeplaceinJanuaryandFebruary2019intheWestWingSeminarRoom(unlessstatedotherwise,pleasechecklink).Theyarestructuredinthreeblocks:MRI(Jan15-17),fMRIandConnectivity(Feb13-15),aswellasEEG/MEGandMultimodalImaging(Feb19-23).Workshopsusuallytakeabout2hours,lecturesmaybeshorter.

Attendeesoftheneuroimagingworkshopsareexpectedtohavebasicknowledgeofscientificprogramming(e.g.Matlab,R,Python).Theydon'tnecessarilyhavetoattendtheMRCCBSUworkshopsonMatlab(ResearchModules6and7),buttheyshouldhaveequivalentskills.Iftheydon'thavethis,theymayhavetoteamupwithothermembersofthecourseinordertodothehands-onwork.Laptopswillbeprovidedfortheworkshops.

Extract from the 2018-19 Course HandbookExtract from the 2018-19 Course Handbook

Extract from the 2018-19 Course Handbook

Appendix6:InterdepartmentalSeminars,talksandlecturesTheCambridgeNeurosciencecommunitycollectivelyhosts~350talksandseminarsperannum.Tosignuptoreceiveemailalertsaboutneuroscienceseminars,pleasevisithttp://www.talks.cam.ac.uk/.Aselectionofisshownbelow.Seecompletelisthttps://www.neuroscience.cam.ac.uk/talks/Seminarseries AdrianSeminarsinNeuroscience

When Mondaysat16:30-18:00

Where HodgkinHuxleySeminarRoom,PhysiologyBuilding,DowningSite.Seminarseries BehaviouralandClinicalNeuroscienceSeminars

When Daysvary,13:00-14:00

Where KennethCraikRoom,CraikMarshallBuilding,DowningSite,Cambridge.

Seminarseries FosterTalks

When Thursday16:00-17:00

Where HodgkinHuxleySeminarRoom,PhysiologyBuilding,DowningSite.

Seminarseries ZangwillClub

When Friday,16:30-17:30

Where GroundFloorLectureTheatre,DepartmentofPsychology.

Seminarseries DepartmentofPsychiatry&CPFTThursdayLunchtimeSeminarSeries

When Thursday,12:30-13:30

Where SeminarRoom,HerchelSmithBuilding,ForvieSite..

Seminarseries ComputationalNeuroscience

When Checklinkforupcomingtalks

Where ComputationalandBiologicalLearningLab(http://learning.eng.cam.ac.uk/),DepartmentofEngineering(fordirectionsseehttp://learning.eng.cam.ac.uk/Public/Directions)

Seminarseries ChaucerClub

When Thursday15:30-17:00

Where MRCCognitionandBrainSciencesUnit

Seminarseries ClinicalNeurosciencesSeminarSeries

When UsuallyThursday12:00-13:00

Where JamesFawcettSeminarRoom,vanGeestBuilding

Seminarseries MentalHealthLifeCourseLectureSeries

When Lectureswilltakeplaceonceaterm,checklinkfordetails

Where CambridgeInstituteofPublicHealthLargeSeminarRoom(firstfloor)

Seminarseries WednesdayLunchTimeSeminarSeries(MRCCBSU)

When Wednesday12:30-13:30

Where MRCCognitionandBrainSciencesUnit