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Now in its 46th year, this course reviews the most recent developments andcurrent controversies in the field of internal medicine. Particular emphasis willbe placed on topics of clinical relevance to the practicing physician. The coursewill include:Didactic Lectures – Clinically active faculty from the Department of Medicinewill emphasize recent clinical advances.Year-in-Review Literature Reviews – Faculty will review major articles fromthe general medical specialty literature with immediate importance to clinicalpractice.Clinical Dilemmas – In addition to case presentations to illustrate currentmanagement strategies, a special session on clinical problem-solving will beincluded.Questions and Answers – Ample time will be provided for specific questionsand discussions of problems commonly encountered by course participants.Internal Medicine Topics – Areas to be covered include cardiology, geriatrics,endocrinology, general internal medicine, women’s health, infectious diseases,gastroenterology, hematology and oncology, neurology, rheumatology, andpulmonary disease.Multidisciplinary Topics – Additional topics of interest to the practicinginternist will include issues in women’s health, geriatrics, emergency & hospitalmedicine, and neurology.Advances in Internal Medicine is presented by the Department of Medicine and is sponsored by the Office of Continuing Medical Education of the University of California, San Francisco School of Medicine.

GREENER MEETINGWe're saving paper! The syllabus will be available electronically prior to the course. A printed syllabus book is also available for purchase for an additional $40

TARGET AUDIENCEThis course is designed for practicing internists, family practitioners, and otherprimary care health professionals. It is also appropriate for hospitalists who wish tostay current on recent developments in internal medicine beyond the inpatient setting.

The purpose of this course is to increase competence and improve clinicianpractice in internal medicine. We specifically anticipate improvements in skills andstrategies to:• Better manage commonly encountered chronic medical problems such as

hyperlipidemia, diabetes, osteoporosis, obstructive lung disease, gout, andheadaches, as well as acute conditions such as skin and soft tissue infections,diarrhea, and musculoskeletal injuries;

• Bring practice patterns more in line with current evidence and guidelines withrespect to atrial fibrillation, coronary artery disease, chronic kidney disease,anticoagulation management, contraception, and preoperative medicalevaluation;

• Manage common problems traditionally treated by specialists, such as heartfailure, Hepatitis B & C infections, end-of-life care, rheumatoid arthritis, as wellas recognize the indications for referral to a subspecialist.

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May 7-11, 2018 • June 18-22, 2018

COURSE CHAIR

H. Quinny Cheng, MDProfessor of MedicineCOURSE FACULTY(University of California, San Franciscounless indicated)Theodore Abraham, MDProfessor of MedicineCo-director, UCSF HCM Center ofExcellenceDirector, UCSF Adult CardiacEchocardiography LaboratorySoraya Azari, MDAssistant Professor of MedicineAssociate Director, Primary CareResidency ProgramZuckerberg San Francisco GeneralRobert B. Baron, MD, MSProfessor of MedicineAssociate Dean for Graduate andContinuing Medical EducationJonathan Carter, MDAssociate Professor of SurgeryBariatric & Gastrointestinal Surgery ProgramsProgram DirectorAdvanced GI MinimallyInvasive/Bariatric SurgeryFellowshipKerry Cho, MDProfessor of MedicineDepartment of NephrologyStephanie Cohen, MD, MPHAssistant Professor of MedicineDivision of Infectious DiseasesMedical Director, San Francisco City ClinicKenneth Covinsky, MD, MPHProfessor of MedicineDivision of GeriatricsMadeline Deutsch, MD, MPHAssociate Professor ofClinical Family and Community MedicineDirector, UCSF Transgender CareCenter of Excellence forTransgender HealthNiharika Dixit, MDAssociate Professor of MedicineRena Fox, MDProfessor of MedicineYaron B. Gesthalter, MDAssistant Professor of Pulmonary &Critical Care MedicineJonathan Graf, MDAssociate Professor of MedicineDepartment of RheumatologyHarry Hollander, MDProfessor of Medicine, Division ofInfectious Diseases; DirectorInternal Medicine ResidencyTraining Program

COURSE FACULTY (CONT’D)

S. Andrew Josephson, MDCarmen Castro Franceschi andGladyne K. MitchellNeurohospitalist DistinguishedProfessor and Chair, Department of NeurologyMaya Katz, MDAssistant Professor of NeurologyJeffrey Kohlwes, MD, MPHAssociate Professor of MedicineDirector, VAMC PRIME ProgramAssociate Program DirectorInternal Medicine ResidencyAndrew D. Leavitt, MDProfessor of Medicine (Hematology)and of Laboratory MedicineMedical Director, UCSF Adult Bloodand Marrow Transplant LaboratoryChienying Liu, MDProfessor of MedicineDivision of Endocrinology andMetabolismUmesh Masharani, MB, BS, MRCPProfessor of MedicineDivision of Endocrinology andMetabolismMichelle Melisko, MDProfessor of Medicine (Hematology)and of Laboratory MedicineBradley Monash, MDAssistant Professor of Medicineand Pediatrics; Chief of MedicineServiceElizabeth J. Murphy, MD, DPhilProfessor of MedicineChief, Division of Endocrinologyand MetabolismZuckerberg San Francisco GeneralSusan Philip, MDAssistant Professor of MedicineCenter for AIDS ResearchZuckerberg San Francisco GeneralThomas A. Ports, MDProfessor of MedicineChief, Interventional CardiologyLaura Rosow, MDNeurologistAssociate Director, UCSF ALSCenterHope Rugo, MDProfessor of MedicineDirector, Breast Oncology andClinical Trial EducationUCSF Helen Diller FamilyComprehensive Cancer Center

COURSE FACULTY (CONT’D)

Brian S. Schwartz, MDAssociate Professor of MedicineDivision of Infectious DiseasesRupal Shah, MDAssistant Professor of MedicineDirector, UCSF Interstitial LungDisease ProgramCarlin Senter, MDAssistant Professor of Medicine and of Orthopaedic SurgeryBradley A. Sharpe, MDAssociate Professor of MedicineDivision of Hospital MedicineAssociate Chief, Medical ServiceAssociate Program DirectorInternal Medicine ResidencyProgramAmandeep Shergill, MDAssistant Professor of MedicineSan Francisco VA Medical CenterKanade Shinkai, MD, PhDAssociate Professor of DermatologyProgram Director, DermatologyResidency ProgramKrishan Soni, MD, MBA, FACCAssistant Professor of MedicineDivision of CardiologyDirector of Value Improvement forDOM-UCSF Health SubspecialtyServicesJohn Teerlink, MD, FACC, FAHA,FESC, FRCPProfessor of MedicineDirector, Heart Failure Program and Clinical EchocardiographyLaboratorySan Francisco VA Medical CenterNeeta Thakur, MD, MPHAssistant Professor of MedicineJudith M.E. Walsh, MD, MPHProfessor of Medicine; Women’sHealth Clinical Research CenterEric Widera, MDAssistant Professor of Medicine;Director, Hospice & Palliative CareSan Francisco VA Medical CenterLisa G. Winston, MDProfessor of MedicineDivision of Infectious Diseases;Vice Chief, Inpatient MedicalServices and HospitalEpidemiologist, Zuckerberg San FranciscoGeneral Hospital

Presented by the Department of MedicineUniversity of California, San Francisco

46th Annual

Advances in Internal Medicine

Earn a Full Year's MOC & CME Credit RequirementsFeatures an Electronic Audience Response System

Hugo Quinny Cheng, MDProfessor of MedicineUniversity of California, San Francisco

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_________________________________________________________________Last Name First M.I._________________________________________________________________Degree Specialty _________________________________________________________________ Address _________________________________________________________________ City State Zip _________________________________________________________________Daytime Phone Fax_________________________________________________________________Email

Address Label Code Letter (see address label: example, A, B, C, D, etc.) ____________________

Would you like to be on our priority email list? £ Yes £ No

Date of birth to be used as OCME registrant number: ___ ___ /___ ___ / X X Month Day

Please indicate if you have any special needs:_____________________________________

Registration Fees £ $950 Practicing Physicians£ $750 Nurses/Pharmacists/Physicians Assistants/Allied Health Professionals/

Residents/Fellows £ $40 Optional Printed Syllabus

Course (Select One):£ May 7-11, 2018 MDM18M19 – Holiday Inn Golden Gateway • San Francisco, CA£ June 18-22, 2018 MDM18M20 – UCSF Parnassus Campus, Cole Hall • San Francisco, CA

Make checks payable to UC RegentsPlease charge my credit card: £ Visa £ MasterCard £ AmEx for $ _________________________

________________________________________________|________/_______Card # Expiration date___________________________________|_____________________________Name on Card (Please Print) Authorized Signature

Refund Policy: Cancellations received in writing before the first day of the course will be refunded, less a $75 administrative fee. No refunds will be made on cancellations received after that date.Please check our website for up to date information on the course: cme.ucsf.edu

46TH ANNUAL ADVANCES IN INTERNAL MEDICINE

May 7-11, 2018 MDM18M19Holiday Inn Golden GatewayJune 18-22, 2018 MDM18M20UCSF Parnassus Campus, Cole Hall

Mail to : UCSF Office of CMEP.O. Box 45368San Francisco, CA 94145-0368Fax: (415) 502-1795

Online registration: cme.ucsf.eduRegistration Information: (415) 476-5808Course Information: (415) 476-4251

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Monday • May 7 and June 187:00 am Registration and Continental Breakfast8:00 Welcome and Overview H. Quinny Cheng, MDCARDIOLOGY • Moderator: Thomas A. Ports, MD 8:10 G Updates on Heart Failure John Teerlink, MD, FACC, FAHA,

FESC, FRCP9:00 Evaluation of the Athlete Theodore Abrahams, MD9:50 Coffee Break 10:10 G Update on Interventional Cardiology Krishan Soni, MD, MBA, FACC11:00 Thyroid Cases Chienying Liu, MD11:50 am Lunch on OwnGERIATRICS • Moderator: Eric Widera, MD 1:20 G Geriatrics & Palliative Care: Year in Review Eric Widera, MD/

Kenneth Covinsky, MD2:50 Coffee BreakENDOCRINOLOGY • Moderator: Umesh Masharani, MB, BS, MRCP 3:10 G Diabetes Prevention: What Works? Elizabeth J. Murphy, MD, DPhil4:00 P Keynote: Safer Opiate Prescribing Soraya Azari, MD4:50 pm Adjourn

Tuesday • May 8 and June 197:30 am Registration and Continental Breakfast GENERAL INTERNAL MEDICINE & WOMEN’S HEALTH • Moderator: Robert B. Baron, MD, MS8:00 Current Concepts in Caring for Transgender Madeline Deutsch, MD, MPH

Patients8:50 Current Issues in Hepatitis Rena Fox, MD9:40 Coffee Break 10:00 G Managing Hypertension in 2018: How Do We Robert B. Baron, MD, MS

Work With Conflicting Data and Conflicting Guidelines?

10:50 Updates in General Internal Medicine: Jeffrey Kohlwes, MD, MPHYear in Review

11:40 am Lunch 1:10pm P Understanding Sports Concussions: Should Our Carlin Senter, MD

Kids Be Playing Contact Sports? 2:00 Update in Women's Health: Year in Review Judith M.E. Walsh, MD, MPH2:50 Coffee BreakHOSPITAL MEDICINE • Moderator: H. Quinny Cheng, MD 3:10 Updates in Hospital Medicine Bradley A. Sharpe, MD4:00 Updates in Perioperative Medicine H. Quinny Cheng, MD4:50 pm Adjourn

G - Satisfies the California requirement for Geriatric CMEP - Satisfies the California requirement for Pain CME

46th Annual

Advances in Internal Medicine ACCREDITATIONThe University of California, San Francisco School ofMedicine (UCSF) is accredited by the AccreditationCouncil for Continuing Medical Education to provide continuing medical education for physicians. UCSF designates this live activity for a maximum of30.25 AMA PRA Category 1 CreditsTM. Physiciansshould claim only the credit commensurate with the extent of their participation in the activity.This CME activity meets the requirements underCalifornia Assembly Bill 1195, continuing educationand cultural and linguistic competency.Geriatric Medicine: The approved credits shownabove include 7.50 geriatric credits toward meetingthe requirement under California Assembly Bill 1820,Geriatric Medicine.Pain Management and Care for the Terminally Ill:The approved credits shown above include 2.50 AMAPRA Category 1 CreditsTM towards meeting therequirement under California Assembly Bill 487, Pain Management and Care for the Terminally Ill.Nurses: For the purpose of recertification, theAmerican Nurses Credentialing Center accepts AMA PRA Category 1 CreditsTM issued by organizations accredited by the ACCME.

Pharmacy: The California Board of Pharmacyaccepts as continuing professional education thosecourses that meet the standard of relevance to pharmacy practice and have been approved for AMA PRA Category 1 CreditTM. Physician Assistants: AAPA accepts category 1credit from AOACCME, Prescribed credit from AAFP, and AMA category 1 credit for the PRA for organizations accredited by the ACCME.American Board of Internal Medicine (ABIM) MOC: Successful completion of this CME activity, whichincludes participation in the evaluation component,enables the participant to earn up to 30.25 MOCpoints in the American Board of Internal Medicine’s(ABIM) Maintenance of Certification (MOC) program.Participants will earn MOC points equivalent to theamount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submitparticipant completion information to ACCME for thepurpose of granting ABIM MOC credit.Family Physicians: Application for CME credit has been filed with the American Academy of Family Physicians. Determination of credit is pending.

Wednesday • May 9 and June 207:00 am Registration and Continental Breakfast INFECTIOUS DISEASES • Moderator: Lisa G. Winston, MD8:00 Cutaneous Infections Kanade Shinkai, MD, PhD8:50 Vaccines: What's New? Lisa Winston, MD9:40 Coffee Break 10:00 UTI Update Brian S. Schwartz, MD10:50 STDs - Now More Than Ever Stephanie Cohen, MD, MPH (May)

Susan Philip, MD (June)11:40 am Lunch 1:10pm Clinical Problem Solving Harry Hollander, MDGASTROENTEROLOGY • Moderator: H. Quinny Cheng, MD 2:00 Celiac Disease & Gluten Sensitivity Amandeep Shergill, MD2:50 Coffee Break 3:10 Update on Bariatric Surgery Jonathan Carter, MD4:00 Cognitive Heuristics & Preventing Diagnostic Bradley Monash, MD

Errors4:50 pm Adjourn

Thursday • May 10 and June 217:30 am Registration and Continental Breakfast HEMATOLOGY AND ONCOLOGY • Moderator: Hope Rugo, MD8:00 Updates in Hematology: Thrombosis & Cytopenias Andrew D. Leavitt, MD8:50 Updates in Cancer Screening Niharika Dixit, MD9:40 Coffee Break 10:00 Cancer Survivorship: What You Need to Know Michelle Melisko, MD10:50 Nephrology Updates & Perspectives for Kerry Cho, MD

the Generalist11:40 am Lunch NEUROLOGY • Moderator: S. Andrew Josephson, MD 1:10pm Neuropathy Pearls for the Generalist Laura Rosow, MD2:00 Parkinson's Disease 2018 Maya Katz, MD2:50 Coffee BreakRHEUMATOLOGY • Moderator: Jonathan Graf, MD 3:10 GP The Year in Review in Rheumatology Jonathan Graf, MD4:00 GP Advances in Rheumatoid Arthritis: Diagnosis, Jonathan Graf, MD

Prognosis & Treatment 4:50 pm Adjourn

Friday • May 11 and June 227:30 am Registration and Continental Breakfast PULMONARY • Moderator: H. Quinny Cheng, MD8:00 Interstitial Lung Disease Rupal Shah, MD8:50 Asthma Updates Neeta Thakur, MD, MPH9:40 Coffee Break 10:00 Diagnostic & Therapeutic Approaches for Yaron B. Gesthalter, MD

Pleural Disease10:50 Advances in Internal Medicine Quiz Show: What H. Quinny Cheng, MD

Have We Learned?11:40 am Adjourn

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UCSF Parnassus CampusCole Hall, Medical Sciences Building513 Parnassus AvenueSan Francisco, CA 94122

Holiday Inn Golden Gateway1500 Van Ness AvenueSan Francisco, CA 94109(415) 441-4000

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May 7-11, 2018 • Holiday Inn Golden Gateway June 18-22, 2018 • UCSF Parnassus Campus (Cole Hall)

GENERAL INFORMATIONAdvanced registration closes two (2) business daysprior to start of course. REGISTRATION INFORMATIONTuition: $950 Practicing Physicians

$750 Nurses/Pharmacists/PhysiciansAssistants/Allied HealthProfessionals/Residents/Fellows

GREENER MEETINGWe're saving paper! The syllabus will be availableelectronically one week prior to the course. Optionalpurchase of a printed syllabus is available for anadditional $40.

Payment may be made by Visa, MasterCard, AmEx or check. REGISTER VIAOnline: cme.ucsf.edu

Mail: Complete course registration form and send with payment to:

UCSF Office of CMEP.O. Box 45368San Francisco, CA 94145-0368

Fax: Fax completed registration form to:(415) 502-1795 (be sure to includeyour credit card number)

Phone: To register by phone or to inquire about registration status, please call UCSF’s CME Registration Office at (415) 476-5808. Please check our website for up-to-date informationon the course: cme.ucsf.eduREFUND POLICYCancellations received in writing before the first day of the course will be refunded, less a $100administrative fee. No refunds will be made oncancellations received after that date.

CONFERENCE LOCATIONThe May Session of this conference will take place at the Holiday Inn Golden Gateway Hotel.Featuring chic décor, a new restaurant, and a centrallocation, while still offering affordable rates comparedto other San Francisco hotels, this full-service hotel iscentered between Nob Hill, Fisherman's Wharf, andthe Golden Gate Bridge, which offers an oasis forSan Francisco hotel guests looking for a true cityexperience.

CONFERENCE LOCATION (CONT’D)A block of guestrooms has been reserved at thespecial UCSF conference rate of $219/night forthe May sesssion. You are urged to make yourreservations early. The cut-off date is April 6, 2018, or until the group room block is filled. After this date,rooms will be provided on a space-available basisonly. To make hotel reservations on-line, go tocme.ucsf.edu and click on the hotel link in the Travel & Lodging section of the course webpage. If you prefer to telephone in your reservation, call 800-272-7098 and please identify yourself as amember of this UCSF conference to receive thespecial rate.The June Session is being held at Cole Hall on theUCSF Parnassus Campus at 513 Parnassus Avenue.Our preferred location for room reservations is theStanyan Park Hotel, conveniently located at 750Stanyan Street (cross street: Waller). The StanyanPark Hotel is offering a starting rate of $208/night.Additional upgraded room rates are available. Tomake your reservation, call 415-751-1000.By staying at the host hotel, you help UCSF meetits contractual obligations and keep registrationfees reasonable.RENTAL CARHertz is offering special rates for participants of thisconference; simply call 800-654-2240 and refer toconvention number # 03BW0137, or call your travelagent. You may also make reservations atwww.Hertz.com. Advance reservations arerecommended.AIR TRANSPORTATIONUCSF has negotiated special fares with UnitedAirlines for our course attendees. You may use thefollowing tour code to book on your own:United – www.united.com code: ZZ26868008Please check our website for up-to-date informationon the course: cme.ucsf.edu