course curriculum · 1. compulsory courses (1) the student must take introduction to dentistry,...

2015 Academic Year

Course Curriculum (Syllabus)

Tohoku University, Graduate School of Dentistry

Table of contents

1. Curriculum policy and Diploma policy ----------------------------------------------- 1 2. Completion Requirements and Registration Procedures ----------------------- 3 3. About foreign student dentistry clinical inspection simulation training -- 9 4. The Institute for International Advanced Research and Education -------- 9 5. Joint Lectures ------------------------------------------------------------------------------ 11 6. 2015 Academic Calendar ---------------------------------------------------------------- 12 7. Educational Goals and Class Plan by Subject (Master’s Course) ----------- 13 8. Educational Goals and Class Plan by Subject (Doctoral Course) ----------- 59 9. Student Counseling Center ------------------------------------------------------------ 151

1. Curriculum policy and Diploma policy (Master’s Course) Curriculum policy

The Master’s course curriculum, which is designed to provide flexible programs that meet students’ interests, consists of a wide range of basic and specialized subjects, beginning with Introduction to Dentistry, and covering subjects needed for future dentistry and oral science such as Medical and Dental Biomaterials, Theory of Medical/Dental Equipment, Food Science, International Dental Health, and Social Dentistry. Each student studies under the guidance of more than one instructor. During the first year, students take Introduction to Dentistry as well as Introduction to Clinical Dentistry and Practical Training at Hospitals to acquaint themselves with dentistry and dental medicine. In the Special Training for the Master’s Thesis, which covers the period from the rst to second years to the completion of a Master’s thesis, students study the Basic Theory of Graduate School Research to familiarize themselves with matters that govern all research, from ethics to technical regulations. They then summarize their research themes and plans as a Summary of Theme Selection, allowing them to begin research at an early stage of the Master’s course. These courses allow dental hygienists and technicians, nurses and other healthcare professionals, as well as graduates in science and engineering, and nutrition and health, to acquire extensive knowledge and advanced research skills in dentistry and oral science that will enable them to contribute to maintaining and promoting these areas in public health.

Diploma Policy

To complete the Master’s course in dentistry, students must be enrolled for two years or more, and earn 30 credits or more (18 credits or more from compulsory subjects and 12 credits or more from elective subjects). They must also undergo the necessary research guidance and submit a Master’s thesis, then pass the evaluation and final examinations to be certified as having completed the course.

If a student is recognized to have made outstanding research achievements, only one year of study is required.

Students who are currently employed or subject to other special circumstances are permitted to study for more than two years under the planned schedule, during a period to be determined by the School.

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(Doctoral Course) Curriculum policy

The doctoral course’s dentistry curriculum, in which one student studies under the guidance of more than one instructor, encourages students to begin research at an early stage of their doctoral course, acquire expertise and specialized knowledge, and develop an interdisciplinary outlook. The Special Training for a Doctoral Thesis, provided from the first to the fourth year, helps students develop the skills necessary to write a doctoral thesis. The Basic Theory on Graduate School Research class, taken in the first year, provides students with the mass of rules that a researcher must comply with, from research ethics to various types of regulations. At the Research Theme Selection Conference, first-year students present their research theme and plan, and hold discussions with each other, developing their research skills in the early stages of their doctoral education. Students are required to take the Advanced Theory of Dentistry course from the first year, in which they learn about the latest research from instructors who are experts in various fields. They acquire many different experimental techniques necessary for conducting research in the Experimental Technique Training course. In addition, Dental Seminars, in which small groups of students work with the latest research information, are designed to help develop their sense of purpose and increase their motivation to conduct research. To produce quality theses, assessments from many different viewpoints by multiple instructors are essential. To make this possible, we have been strengthening the screening setup by introducing a system of a preliminary reviewing that uses “contributing a paper to a top-rated international journal” as the chief criterion. At the same time, we provide assistance to students in giving presentations at international academic meetings, with the aim of having them cultivate a global outlook and perspective.

Diploma Policy

To complete the Doctoral course, students are required to be in the program for four years or more, and earn 30 credits or more from the following subjects: nine or more credits for the Advanced Theory of Dentistry course, six or more credits for Dental Seminars, six or more credits for the Experimental Technique Training course, and nine or more credits for Special Training for Doctoral Thesis. Students must also receive the necessary research guidance and submit a Doctoral thesis, then pass the evaluation and the final examination.

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2. Completion Requirements and Registration Procedures (Master’s Course) Completion Requirements

To complete the master’s degree program of Tohoku University Graduate School of Dentistry, the student must take at least 2 years of course work, earn at least 30 credits (18 compulsory credits and 12 elective credits) from the classes shown in Appendix 1 of the syllabus, submit a master’s thesis that adheres to the research guidance, successfully defend the thesis and pass the final examination. Registration Procedures 1. Compulsory courses

(1) The student must take Introduction to Dentistry, Introduction to Clinical Dentistry and Tour of Dental Clinic, according to the class schedule in the first year.

(2) For Basic Technical Courses in Dental Sciences, the student must take at least 3 elective courses (at least 3 credits in total; 1 credit/course) that must be elected in the first or second year.

(3) The student must take a specialty dental course under the guidance of his/her primary advisor in the second year.

(4) The student must take Special Training Course for Master’s Thesis Preparation under the guidance of his/her primary advisor in the first and second year. In the first year, credits will be given for taking Foundation of Graduate School Research , submission of Abstract of Research Theme Selection and acquiring special knowledge during this process.

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2. Elective courses The student must take at least 6 elective courses (12 credits). A registration example is shown for each course in the table below.

1 Course for co-dental personnel

2 Oral health course

3 Course for dental equipment and functional foods development

Oral Biology ○ ○ ○

Oral Pathophysiology ○ ○ ○ Medical and Dental Bio-materials ○ * ○ Medical and Dental Device Science ○ * ○

Food Science ○ * ○

International Oral Health ○ ○ ○

Social Dentistry ○ ○ ○

Comprehensive Dentistry ○ ○ ○ Oral Health Care for Children and Adolescents ○ ○ *

Oral Restoration ○ ○ ○

Stomatognathic Function ○ * *

Special needs Dentistry ○ ○ *

Geriatric Dentistry ○ ○ ○

Dental Infection Control ○ ○ * Oral and Maxillofacial Reconstruction ○ ○ ○ Oral Immunological Disease Control * * *

Longevity Oral Science * * *

Oral Health Science Theory * * * Oral Care Program for Cancer Patients ○ ○ ○

*:This course has specific restrictions. Discuss with your primary advisor before selecting this course. Oral Care Program for Cancer Patients (1 credit);at least 6 other courses need to be completed to meet the master’s degree requirements because the student can earn only 1 credit by taking this course.

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(Doctoral Course) Completion Requirements

Students who intend to complete the Doctoral Course in this Graduate School

must be enrolled for four years or more in the same course, must acquire 30 or more credits from course subjects (9 or more credits from Lectures in Dental Sciences, 6 or more credits from Seminars in Dental Sciences, 6 or more credits from Technical Courses in Dental Sciences, and 9 credits from Courses for Thesis Preparation, Table 1), and after receiving the required research guidance, must submit a Doctoral dissertation and pass a dissertation evaluation as well as a final examination.

However, in accordance with the provisions of the Graduate School Council of this Graduate School stated elsewhere, an enrollment period of three or more years shall be sufficient for the Doctoral Course, if the student is recognized to have achieved superior research results.

Under some circumstances, such as the student being employed, the Graduate School Council of this Graduate School may grant permission to take an educational program over a planned, fixed period that exceeds the standard course term (four years for the Doctoral Course) upon request. Those enrolling under this system are called "Long-term Students," and must pay total tuition fees equal to those paid by students who complete their studies within normal year limits. Registration Procedures 1. Students must register for subjects from a total of three or more of the

departments offered in Lectures in Dental Sciences, Seminars in Dental Sciences and Technical Courses in Dental Sciences. including at least one subject offered by the academic division with which the student is affiliated.

Lectures in Dental Sciences: 3 credits per class in each department, for a total of 9 or more credits Seminars in Dental Sciences: 2 credits per class in each department, for a total of 6 or more credits Technical Courses in Dental Sciences: 2 credits per class in each department, for a total of 6 or more credits

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*Joint lecture: Consult with the head instructor before registering. Advanced Theory of Oral Health Science(2 credits), Oral Cancer Detection (1 credits): Because the credits is not enough, it is possible to take three subjects each other.

Course Subject

Lectures in Dental Sciences Credits Seminars in Dental

Sciences Credits Technical Courses in Dental Sciences Credits

Courses for Thesis Preparation

Credits

Oral Biology Oral Ecology and Biochemistry 3 Oral Ecology and

Biochemistry 2 Oral Ecology and Biochemistry 2 Oral Biology 9

Dental Pharmacology 3 Dental Pharmacology 2 Dental

Pharmacology 2

Oral Microbiology 3 Oral Microbiology 2 Oral Microbiology 2 Periodontology and Endodontology 3 Periodontology and

Endodontology 2 Periodontology and Endodontology 2

Oral Molecular Bioregulation 3 Oral Molecular

Bioregulation 2 Oral Molecular Bioregulation 2

Oral Function and Morphology

Oral and Craniofacial Anatomy

3 Oral and Craniofacial Anatomy

2 Oral and Craniofacial Anatomy

2 Oral Function and Morphology

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Dental and Digital Forensics 3 Dental and Digital

Forensics 2 Dental and Digital Forensics 2

Oral Physiology 3 Oral Physiology 2 Oral Physiology 2

Advanced Prosthetic Dentistry 3 Advanced Prosthetic

Dentistry 2 Advanced Prosthetic Dentistry

2

Aging and Geriatric Dentistry 3 Aging and

Geriatric Dentistry 2 Aging and Geriatric Dentistry 2

Comprehensive Dentistry 3 Comprehensive

Dentistry 2 Comprehensive Dentistry 2

Restorative Dentistry Dental Biomaterials 3 Dental Biomaterials 2 Dental Biomaterials 2 Restorative

Dentistry 9

Operative Dentistry 3 Operative Dentistry 2 Operative Dentistry 2

Molecular and Regenerative Prosthodontics

3 Molecular and Regenerative Prosthodontics

2 Molecular and Regenerative Prosthodontics

2

Oral Health and Development Sciences Preventive Dentistry 3 Preventive Dentistry 2 Preventive

Dentistry 2 Oral Health and Development Sciences

9

Pediatric Dentistry 3 Pediatric Dentistry 2 Pediatric Dentistry 2 Orthodontics and Dentofacial Orthopedics

3 Orthodontics and Dentofacial Orthopedics

2 Orthodontics and Dentofacial Orthopedics

2

Oral Dysfunction Science 3 Oral Dysfunction

Science 2 Oral Dysfunction Science 2

International Oral Health 3 International Oral

Health 2 International Oral Health 2

Oral Medicine and Surgery Oral Pathology 3 Oral Pathology 2 Oral Pathology 2 Oral Medicine

and Surgery 9

Oral Diagnosis 3 Oral Diagnosis 2 Oral Diagnosis 2 Oral and Maxillofacial Surgery

3 Oral and Maxillofacial Surgery 2

Oral and Maxillofacial Surgery

2

Dento-oral Anesthesiology 3 Dento-oral

Anesthesiology 2 Dento-oral Anesthesiology 2

Craniofacial Engineering and Regeneration

Craniofacial Development and Regeneration

3 Craniofacial Development and Regeneration

2 Craniofacial Development and Regeneration

2 Craniofacial Engineering and Regeneration

9

Craniofacial Function Engineering

3 Craniofacial Function Engineering

2 Craniofacial Function Engineering

2

Community Oral Health Science Community Oral

Health Science 3 Community Oral Health Science 2 Community Oral

Health Science 2 Community Oral Health Science

9

Molecular Pathogenesis of Oral Tumor

Oral Cancer Therapeutics 3 Molecular

Pathogenesis of Oral Tumor

2

Oral Cancer Therapeutics 2 Molecular

Pathogenesis of Oral Tumor

9

Molecular Oral Oncology 3 Molecular Oral

Oncology 2

Bio-Dental Engineering Bio-Dental Engineering 3 Bio-Dental

Engineering 2 Bio-Dental Engineering 2 Bio-Dental

Engineering 9

Intractable Diseases and Immunology Intractable Diseases

and Immunology 3 Intractable Diseases and Immunology 2

Intractable Diseases and Immunology

2 Intractable Diseases and Immunology

9

Immune Regulation and Oral Immunity* Immune Regulation

and Oral Immunity 3 Immune Regulation and Oral Immunity 2

Immune Regulation and Oral Immunity

2 Immune Regulation and Oral Immunity

9

Geriatric Oral Science* Geriatric Oral Science 3 Geriatric Oral

Science 2 Geriatric Oral Science 2 Geriatric Oral

Science 9

Oncology dentist course Clinical Oncology I 3

Clinical Oncology II 3 Clinical Oncology III 3

Advanced Theory of Oral Health Science (specialized classes)

2 Oral Cancer Detection 1

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2. Courses for Thesis Preparation confer specialized knowledge, and allow the conducting of independent research relevant to preparation of the Doctoral thesis under guidance from an academic advisor in the field to which the graduate student belongs. There is no set curriculum for the instruction received for preparing the thesis (for which 1 credit is awarded in the 1st year, 4 in the 2nd year, and 4 in the 3rd year, for a total of 9 credits), as it will differ for each graduate student depending on the content and stage of their research. However in their first year students shall receive one credit for attending Introduction to Research, presenting at theme selection meetings, and acquiring specialized knowledge in connection with these activities. Details regarding the theme selection meetings will be provided at a later date. Students shall be awarded eight credits for participating in “journal club”, clinical conferences, research seminars, research progress reports and medical examinations held individually in each department, and acquiring specialized knowledge by attending and presenting at academic conferences from their second through third year. Fourth-year students shall publish the research results they have obtained up to that point in their Doctoral theses. In cases where the Graduate School Committee judges a student enrolled for two or more years to have performed outstanding research, and to be ahead of schedule in their research progress, that student may be permitted to submit a Doctoral thesis based on credits they are expected to obtain in their third year. 3. Earning Credits (1) A maximum of three subjects can be taken per year in each of Lectures in

Dental Sciences, Seminars in Dental Sciences, and Technical Courses in Dental Sciences.

(2) Credit can be earned in Lectures in Dental Sciences, Seminars in Dental Sciences, and Technical Courses in Dental Sciences up until the student's third year. A student could also take one or two courses over two to three years; for example, they could take six credits in Lectures in Dental Sciences and two credits each in Seminars in Dental Sciences and Technical Courses in Dental Sciences during their first year, three credits in Lectures in Dental Sciences and two credits each in Seminars in Dental Sciences and Technical Courses in Dental Sciences during their second year, and then take two credits each in Seminars in Dental Sciences, and Technical Courses in Dental Sciences during their third year. A table of average credit acquisition per academic year is shown below.

1st Year 2nd Year 3rd Year 4th year Total

Lectures in Dental Sciences 9 9

Seminars in Dental Sciences 4 2 6 Technical Courses in Dental Sciences 2 4 6

Courses for Thesis Preparation 1 4 4 9

Total Credits 16 10 4 30

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4. Course Registration Procedure

Students must register for subjects chosen from Lectures in Dental Sciences, Seminars in Dental Sciences, and Technical Courses in Dental Sciences within the designated registration period. Details on registration procedure will be provided at the Orientation.

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3. About foreign student dentistry clinical inspection simulation training

In this graduate course, I perform dentistry clinical inspection simulation training for a foreign student. Since it is very useful training in order that this may study basic dentistry, the foreign student needs to participate at any cost.

Although this training carries out a summer closure period mainly, since it carries out also during the winter closure when it can never participate, participate in either at any cost.

In addition, I connect a concrete schedule each time.

4. The Institute for International Advanced Research and Education (Master’s Course)

Tohoku University Institute for International Advanced Research and Education is a post-graduate educational organization that supports the training of world-class young researchers with outstanding knowledge and creative “integrated intelligence” by blending different specialties to pioneer and study new research fields. Institute for International Advanced Research and Education aims to supplement and enhance the functions of existing graduate schools and institutes by establishing 5 new multi-disciplinary research fields based on the organic coordination of outcomes from 12 global COE programs and by training world-class young researchers.

To be selected as a master’s research trainee at the Institute, the student must earn at least 6 credits specified by the Institute in the first year of the master’s program at the Graduate School of Dentistry, and apply for the selection screening of the Institute at the end of the first year. Selected students will be eligible to receive scholarships and other grants for paper submissions and attendance at scientific meetings and international conferences from the second year. In principle, Master’s research trainees will be selected from among students who plan to pursue doctoral degrees.

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(Doctoral Course) The Tohoku University Institute for International Advanced Research and

Education is an educational organization of the graduate school which strives to open new fields of research by combining different fields, and use the knowledge obtained from this process to encourage the development of young world-class researchers who possess outstanding intellect, creativity, and an education in "comprehensive knowledge." This institute is organically connected to the thirteen 21st century COE Programs, allowing it to address various new multidisciplinary research areas. By furthering the development of young, world-class researchers, it complements the functions of the university's existing graduate schools and research institutes.

Students wishing to become Doctoral research institute students should apply at the end of the first year of their Doctoral course and undergo the prescribed selection process. Selected students will receive a scholarship award starting the second year of their Doctoral course and receive financial aid for costs related to their thesis, academic societies, and attending international academic conferences. They will also be able to receive aid for research expenses commensurate with their research plan and for international internships. Graduate students must take the assigned course in Oral Health Science (see syllabus) of this institute. In this course, students will study Oral Health Science through a combination with dentistry, engineering, and material sciences.

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5. Joint Lectures I. Immune Regulation and Oral Immunity (joint lecture)

The Tohoku University Graduate School of Dentistry is promoting "Interface Oral Health Science" as the next step in dentistry. One area of this research is the host/parasite interface; our program, focused on the Oral Biology course, is one of the most advanced area in Japan.

The oral immune response is crucial to understanding biological defenses, and inflammations of the salivary glands and oral mucosa caused by irregularities in the immune response have a large impact on the patient's quality of life. This course addresses their regulation and control.

This University has a basic agreement with the National Center for Global Health and Medicine (http://www.imcj.go.jp/rese/top/index.html) through which it is promoting understanding and control of oral diseases related to immune response, and planning the joint course in Immune Regulation and Oral Immunity (syllabus TBD) taught by researchers from this institute in order to foster highly specialized professionals.

II. Geriatric Oral Science (joint lecture)

Due to the aging of the Japanese population, research and education aimed at building a foundation for serving the elderly has become critical. However, currently universities have not adequately established groundwork for research in geriatric sciences, let alone in geriatric oral science. In response to these trends in Japanese society, the creation of a foundation for geriatric oral science and the fostering of professionals capable of creating and applying knowledge in this field are pressing issues.

This University has a basic agreement with the National Center for Geriatrics and Gerontology (http://www.nils.go.jp/) through which it is promoting geriatric oral science research, and planning the joint course in "Geriatric Oral Science" (syllabus TBD) taught by researchers from this institute in order to foster highly specialized professionals. III. Molecular Imaging Educational/Training Course

This course is a joint venture of the graduate schools of medicine, dentistry, pharmaceutical science and engineering. It is based in the Tohoku University Cyclotron and Radioisotope Center, and National Institute of Radiological Sciences. Backed by a track record of research results, the course aims to foster molecular imaging researchers through an interdisciplinary education and research system. The Tohoku University Graduate School of Dentistry is engaged in research on molecular imaging in the field of dentistry, and is striving to create researchers and medical professionals capable of utilizing PET. Master and Doctoral Students belonging to the School of Medicine, Graduate School of Dentistry, Graduate School of Pharmaceutical Sciences, or School of Engineering can take this course.

IV. Tumor specialized dentist course

Since it contributes to local cancer medical treatment, it is a course aiming at training the dentist (oral surgeon) well versed in the diagnosis and the cure for cancer of the mouth.

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Description Schedule

Entrance Ceremony Apr. 3 (Fri.),2015

Orientation (1st year students) Early Apr.

1st semester classes Apr.—Sep.

Registration Mid Apr.

Student Health Check May

Anniversary of University's founding 22-Jun

Graduate School Entrance Examinations (1st) July

Registration Mid Oct.

Preliminary Doctoral Thesis Examination(4th year Doctoral students) Sep.—Oct.

Research Theme Selection Meetings(1st year doctoral students) October

Deadline to submit doctoral thesis(2nd year Master and 4th year Doctoral

students)Mid Dec.

Graduate School Entrance Examinations (2nd) Mid Dec.

2nd semester classes (after Winter Vacation) Jan.—Mar.

Announcement of graduation/completionapproval Planned for Feb. 18 (Thu.)

Degree Conferral Ceremony Mar. 25 (Fri.),2016

*This calendar is provisional. There may be changes to the schedule.

2nd semester classes (up to Winter Vacation) Oct.—Dec.

6. 2015 Academic Calendar for the School/Graduate School of Dentistry

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7. Educational Goals and Class Plan by Subject (Master’s Course)

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Course Subject Basic Technical Courses in Dental Sciences: Aging and Geriatric Dentistry

Instructor (circle name of main Instructor)

○ Yoshinori Hattori et al.

Credits 1

Day/time of classes Consult with learners Place Laboratory of Aging & Geriatric

Dentistry

Aims & Content of Class

[Aims]

This training class is aimed to learn the research methods for capturing, analyzing, and evaluating stomatognathic functions.

[Contents]

1) Registration, analysis and evaluation of jaw motion 2) Registration, analysis and evaluation of electromyographic

activities of the jaw muscles 3) Registration, analysis and evaluation of masticatory function 4) Registration, analysis and evaluation of dental occlusion

Text/Materials/References etc. None

Method of evaluating performance By presence and report

Comments Day/time of this class is flexible. Students should contact the following before registration. Prof.HATTORI [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: Comprehensive Dentistry


○ Masahiko KIKUCHI Akio IZUMIDA Naoki ENDO

Credits 1

Day/time of classes

First Term Monday /4th Period Place Office of Comprehensive

Dentistry


[Aims] To learn the theoretical and practical methods for dental education especially related to the post clinical training program. [Contents] 1. History of dental education 2. Theory of dental education 3. Objectives of dental education 4. Methods for dental education 5. Evaluation for dental education

Text/Materials/References etc. Materials

Method of evaluating performance By report

Comments Day/time and place of this class are flexible. Students should contact the following before registration. Prof.KIKUCHI [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: Dental Biomaterials


○ Yukyo TAKADA Masatoshi TAKAHASHI Taichi TENKUMO Guang Hong

Credits 1

Day/time of classes Consult with students Place Div. of Dental Biomaterials,

(Building A, 4F)


[Aims]

The aim is to practice the research technique for observation methods and elemental analyses working for own research theme, using a scanning electron microscope (SEM) with energy dispersive X-ray spectrometry (EDS).

[Contents]

Principle of a scanning electron microscope

Preparation of specimens Observation methods Principle of an electron probe X-ray microanalyzer Preparation of specimens Elemental analysis methods

Qualitative analysis Quantitatively analysis Mapping analysis

Text/Materials/References etc. Non

Method of evaluating performance By presence and reports

Comments

The lecture days will be adjusted after consultation with students who take this course. (Attendance in all day is necessary on lecture days.) Students should contact the following before registration. Assoc. Prof.TAKADA [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: Operative Dentistry


○ Masahiro SAITO

Credits 1

Day/time of classes Consult with learners Place Staff Room of Division of

Operative Dentistry


[Aims] To understand the periodontal tissue destruction by chronic inflammatory disease, establishment of animal model are necessary. In this lecture, basic knowledge for immunohistochemical analysis is explained to evaluate animal model of periodontal disease. [Contents] 1) Basic knowledge of histochemical analysis

To understand how to prepare tissue section of periodontal disease model.

2) Basic knowledge of fluorescence microscopy To understand basic of knowledge of fluorescence imaging, and how to fluorescence microscope.

3) Basic knowledge of confocal immunofluorescence microscopy To understand basic of knowledge of confocal imaging, and how to confocal laser scanning microscopy .

Text/Materials/References etc.

Method of evaluating performance

Comments Students should contact the following before registration. Prof.SAITO [email protected]

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Course Subject

Basic Technical Courses in Dental Sciences: Molecular and Regenerative Prosthodontics


○ Hiroshi EGUSA Masahiro YAMADA

Credits 1

Day/time of classes Consult with learners Place

Laboratory of the Division of Molecular and Regenerative Prosthodontics


[Aim] To learn the basic experimental skills for research of molecular and regenerative prosthodontics. [Contents] 1. Lectures on stem cell culture 2. Stem cell culture 3. Guided differentiation of stem cells 4. Discussion and reports on the outcome of the experiments

Text/Materials/References etc. At the Bench: A Laboratory Navigator, Kathy Barker

Method of evaluating performance Attendance records and reports

Comments

Number of participants may be limited. Applicants should contact with Prof. Egusa before registration. Students should contact the following before registration. Prof.EGUSA [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: Preventive Dentistry


○ Takeyoshi KOSEKI Ryouichi HOSOKAWA Naoko TANDA

Credits 1

Day/time of classes Thursday, 3rd period Place Consult with learners


[Aims] Aims are to learn the skills of public health and preventive dentistry for promoting the motivation toward the oral health in the social activity. [Contents] Basic technical training #1 (in January) ･Environmental measurement ･Measurement of atmospheric pollution ･Water quality measurement ･Anthropometric Basic technical training #2 (in July) ･Diagnostic method of early caries lesions ･Oral hygiene method ･Oral Examination method ･Application of fluoride ･Caries-activity test and hemoccult test ･Examination method of periodontal condition

Text/Materials/References etc. Instruct in the beginning of the class.

Method of evaluating performance Attendance and reports.

Comments

Day/time and place of this class are flexible. Consult with instructors. Students should contact the following before registration. Prof. KOSEKI [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: Pediatric Dentistry


○ Satoshi Fukumoto

Credits 1

Day/time of classes

Jun, Oct (Fri 1st and 2nd period) Place suspense


[Aims] Purpose of this course is learning the culture methods of dental epithelium and mesenchyme to analyze their differentiation. [Contents] 1) Culture and evaluation of dental epithelial and mesenchymal cells

proliferation. 2) Isolation of mRNA from dental epithelial and mesenchymal cells. 3) Culture of tooth germ and salivary gland from embryonic day 13

mouse. 4) Protein purification of enamel matrix from postonatal day 7 mouse.


Method of evaluating performance Attendance record and reports

Comments

Please confirm the schedule of course Students should contact the following before registration. Prof.FUKUMOTO [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: Orthodontics and Dentofacial Orthopedics


○ Teruko TAKANO- YAMAMOTO et al.

Credits 1

Day/time of classes

The time of classes will be decided in consulting with student.

Place Laboratory of Orthodontics and Dentfacial Orthopedics, and etc.


[Aims] The aim is to learn the basic methods of examination and analysis in orthodontic field and related fields, and to learn basic experimental technique to study basic research of biological reaction in orthodontic [Contents] Students learn the examination, analysis and experimental technique of basic knowledge in orthodontic field and related fields by one-to-one. The class contents are decided in consultation with students attending a lecture. Our plans are the following contents. In addition, the master's course is aim at learning a basic technique and theory. 1. Cell culture (Periodontal cells, bone related cells etc.) 2. Animal experimentation (mouse, rat, dog etc.) 3. Orthodontic materials 4. Cephalometric analysis 5. Three-dimensional analysis of stomatognathic function 6. Introduction of medical statistics


In this seminar, handouts will be distributed to students.

Method of evaluating performance Based on attendances of classes and reports

Comments

Students who take this course are required to contact Teruko Takano-Yamamoto, to attend the classes. Students should contact the following before registration. Prof. YAMAMOTO [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: Oral Dysfunction Science


○ Kaoru IGARASHI, and others

Credits 1

Day/time of classes

The 2nd semester, Thursday, The 4th class Place Seminar & Training Room of

Oral Dysfunction Science


[Aims] To learn various examinations and analyses that are necessary for diagnosis, treatment planning, and treatment evaluation of dentofacial anomaly and jaw deformity. [Contents] 1. Various radiographic examinations (Instructors: Kaoru Igarashi and others) 2. Roentgenographic cephalometric analyses (Instructors: Kaoru Igarashi and others) 3. Examinations of various oral functions (Instructors: Kaoru Igarashi and others) 4. Other examinations and analyses (Instructors: Kaoru Igarashi and others)


Assigned textbooks on orthodontics and orthognathic surgery


Comments

Day/time and place of this class are flexible. Consult with instructors. Students should contact the following before registration. Prof. IGARASHI [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: International Oral Health


○ Ken OASKA Jun AIDA

Credits 1

Day/time of classes Consult with learners Place Seminar room of the dept.


The aims of this lecture are: To learn dental health system of Japan as well as other countries. To learn the analytical methods in the epidemiological study, bio-

statistics using SPSS software. Content of class: ・ To make a research protocol in the filed study. ・ To analyze the data using SPSS software. ・ To learn about the strength of evidence of variety of study designs.

Text/Materials/References etc. Instruct at the beginning of the class.


Comments Students should contact the following before registration. Prof.OSAKA [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: Oral Ecology and Biochemistry


○ Takuichi SATO, Jumpei WASHIO, Gen MAYAGAGI,

Yuki ABIKO Credits 1

Day/time of classes Monday 14:40-16:10 Place Division of Oral Ecology and

Biochemistry


[Aims] The aim of this training course is to obtain and master the research technique on oral ecosystem, oral biofilm and oral diseases, such as dental caries, periodontal diseases and halitosis, in order to perform experiments in the Division of Oral Ecology and Biochemistry. [Contents] Students who take this course may learn basic biochemical methods including spectrophotometric and enzymatic analyses, and molecular biological methods including polymerase chain reaction and sequencing. Furthermore, students may learn advanced procedures on plaque bacterial culture and handling, and advanced anaerobic techniques utilizing an anaerobic glove box.


Method of evaluating performance Evaluation will be done based on submitted reports.

Comments Students should contact the following before registration. Prof. TAKAHASHI [email protected]

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Course Subject Basic Technical Courses

in Dental Sciences: Oral Pathology


○ Hiroyuki KUMAMOTO

Credits 1

Day/time of classes

First semester Fri 4 Place Division of Oral Pathology


[Aims] Preparation and histological observation of tissue specimens are learned. [Contents] Preparation of tissue specimens, containing fixation, embedding, sectioning, and staining, are exercised. Findings of these specimens are discussed.

Text/Materials/References etc. None specified.

Method of evaluating performance Attendance and discussion.

Comments Students should contact the following before registration. Prof. KUMAMOTO [email protected]

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Course Subject Basic Technical Courses in Dental Sciences: Oral Diagnosis


○ Takashi SASANO Maya SAKAMOTO Noriaki SHOJI Masahiro IIKOBO

Credits 1

Day/time of classes

Fridays, 3rd and 4th peri-ods

Place Laboratory of Oral Diagnosis


[Aim] To acquire knowledge to diagnose the oral disease comprehensively with the overall information obtained from an interview to the patient, the clinical findings and the diagnostic images. [Content] ・To teach clinical diagnosis for oral and maxillofacial diseases based on the patient’s history, clinical findings, laboratory data and diagnos-tic imaging (lecture). Text/Materials/



Comments Students should contact the following before registration. Prof. Takashi SASANO [email protected]

26

Course Subject Basic Technical Courses in Dental Sciences : Oral and Maxillofacial Surgery


○ Tetsu TAKAHASHI Shiro MORI Wataru HASHIMOTO

Credits 1

Day/time of classes

Friday, 4th and 5th hour Second semester Place

Div. of Oral and Maxillofacial Surgery, 10F East Ward, 3F Outpatient Section


【Aims】 To master basic research technique for the development of basic research and clinical research of oral and maxillofacial surgery 【Contents】 1. To learn how to make a frozen section, how to make a pathological

tissue section, a various kind of staining method 2. To learn tissue morphometrics 3. To learn biomaterial for implant, soft tissue and hard tissue interface

observation, analysis method 4. Methods for researches on control of tumors on oral and maxillofacial

region 5. To learn experimental method of bone disease treatment

Text/Materials/References etc. A report should be presented suitably.


It judges by the check of the degree of comprehension by the number of times of attendance, and a report, etc.

Comments

Opening time and a course content may be changed after consulting with a participant. Students should contact the following before registration. Prof.Tetsu TAKAHASHI [email protected]

27

Course Subject Basic Technical Courses in Dental Sciences: Dento-oral Anesthesiology


○ Eiji MASAKI Kentaro MIZUTA Kanta KIDO Makoto YASUDA Hiroshi HOSHIJIMA

Astuko MATODA Credits 1

Day/time of classes

The second semester Friday, the 4th period Place

Medical office of Division of Dento-oral Anesthesiology in Clinical Building 4th flower


[Aims] To learn how to make the study design and carry out the research in dento-oral anesthesiology. [Contents] 1. Basic research of anesthesiology i) Study Design ii) Methodology iii) Evaluation of study 2. Clinical research of anesthesiology i) Study Design ii) Methodology iii) Evaluation of study 3. Medical statistics 4. Presentation



Comments

Day/time of this class is flexible Students should contact the following before registration. Prof.MASAKI [email protected]

28

Course Subject

Basic Technical Courses in Dental Sciences: Craniofacial Development and Regeneration


○ Yasuyuki SASANO Megumi NAKAMURA

Credits 1

Day/time of classes TBA (1st -4th semester ) Place TBA


[Aims] This subject aims to learn about technics and methods used for tissue biology and calcified tissue research. [Contents] Animal experiments Transmission electron microscopy Scanning electron microscopy Micro-computed tomography In situ hybridization Immunohistochemistry


Method of evaluating performance Attendance and report

Comments

Details are subject to change Students should contact the following before registration. Prof.Yasuyuki SASANO [email protected]

29

Course Subject Basic Technical Courses in Dental Sciences: Craniofacial Function Engineering


○ Osamu SUZUKI Takahisa ANADA

Credits 1

Day/time of classes Consult with learners Place Laboratory of Craniofacial

Function Engineering


[Aims] To understand the methodology of bone tissue engineering and the materials used such as synthetic biomaterials and stem cells. [Contents] 1. Methodology of bone tissue engineering 2. Analyses of scaffold materials, such as natural polymers and inorganic hydroxyapatite (HA) and octacalcium phosphate (OCP), by x-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy 3. Cell culture



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.SUZUKI [email protected]

30

Course Subject Basic Technical Courses in Dental Sciences: Community Oral Health Science


○ Akito TSUBOI Naru SHIRAISHI

Credits 1

Day/time of classes

The 1st term, Tuesday, 4th – 5th periods Place Laboratory of Community Oral

Health Science


[Aims]

To learn about the outlines of clinical epidemiologic studies in the dentistry.

[Contents]

1. Research design of clinical epidemiology 2. An introduction to genome cohort study 3. Medical statistics 4. Presentation for medical research



Comments

Please confirm the schedule of course. Students should contact the following before registration. Prof.TSUBOI [email protected]

31

Course Subject Basic Technical Courses in Dental Sciences: Department of Oral Cancer Therapeutics


○ Hisanori HORIUCHI

Credits 1

Day/time of classes

To be determined after discussion Place

Laboratory of the Department of Molecular and Cellular biology, Institute of Development, Aging and Cancer, Tohoku University


[Aims] To learn basic technique of biochemistry [Contents]

Basic technical training of protein analysis using biochemical methods such as electrophoresis and immunoblotting.


Method of evaluating performance Attendance and Reports

Comments

The time of course might be changed after mutual talk. Students should contact the following before registration. Prof.HORIUCHI [email protected]

32

Course Subject Basic Technical Courses in Dental Sciences: Molecular Oral Oncology


○ Hozumi MOTOHASHI

Credits 1

Day/time of classes

Consult with Hozumi Motohashi Place

Department of Gene Expression Regulation, Institute of Development, Aging and Cancer


[Aims] To learn the experimental technique of molecular cell biology for the analysis of transcription factors and nuclear proteins. [Contents] Training course of experimental technique of molecular cell biology including cell culture, protein analysis, gene expression analysis and epigenetic analysis



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.MOTOHASHI [email protected]

33

Course Subject Basic Technical Courses in Dental Sciences: Bio-Dental Engineering


○ Shinji KAMAKURA

Credits 1

Day/time of classes

The second semester Monday 13:00~16:10 Place Laboratory of Bone Regenerative

Engineering and others


[Aims] To learn fundamental technical skills concerning about Bio-Dental Engineering

and related field in the course of implantation of biomaterials to the tissues in

experimental animals, such as rats and so on.

[Contents] 1. Implantation procedures of biomaterials in experimental animals

2. Procedures of perfusion fixation

3. Preparation of histopathological specimens of hard tissues

4. Staining technique of histopathological specimens of hard tissues

5. Histomorphometry of histopathological specimens of hard tissues

Text/Materials/References etc. No textbook is used but handouts are distributed.


The evaluation is performed based on the attendance at the class and scores on the submitted reports.

Comments

Opening hours and place of the class will be altered in accordance with consulting with participants. An applicant should attend the education and training by Institute for Animal Experimentation Tohoku University School of Medicine in advance. Because of restriction on number of accepted applicants, an applicant should consult with main instructor beforehand. Students should contact the following before registration. Prof. KAMAKURA [email protected]

34

Course Subject Basic Technical Courses in Dental Sciences: [Dental Pharmacology]


○ Minoru WAKAMORI Takashi YOSHIDA Hisahiko KUBOTA

Credits 1

Day/time of classes Monday / 4-5th Place Mol. Biol. & Biochem. Room in

Lab. of Pharmacol.


[Aims] This course is designed to help students master molecular biological, electrophysiological and pharmacological techniques which enable them to perform their thesis works by themselves. [Contents] We will lecture on the principles of the following techniques, and there-after students will have practical training.

1) Mammalian cell culture 2) PCR analysis 3) Cloning method and sequence analysis 4) Gene transfection 5) Patch-clamp techniques 6) Measurement of changes in the intracellular Ca2+ concentration

Text/Materials/References etc. There is no text for this course.


The largest part of the evaluation will be based on active participation in class activities.

Comments Students should contact the following before registration. Prof. WAKAMORI [email protected]

35

Course Subject Basic Technical Courses in Dental Sciences: Intractable Diseases and Immunobiology


○ Kouetsu OGASAWARA

Credits 1

Day/time of classes T.B.A Place IDAC etc.


[Aim] To acquire the methods for immunology and molecular biology. [Contents] 1. Cellular Immunology methods. 2. Molecular biology and immunology methods.

3. Advanced scientific methods.

Our lab member only. If you take the class, you should belong to our lab.

Text/Materials/References etc. T.B.A

Method of evaluating performance Reports and attendance

Comments

To be discussed contents of the course with students. Students should contact the following before registration. Prof.OGASAWARA [email protected]

36

Course Subject Basic Technical Courses in Dental Sciences: Oral Microbiology


○ Haruhiko TAKADA Hiroyuki TADA Hidemi RIKIISHI et al.

Credits 1

Day/time of classes Consult with learners Place Laboratories of Oral

Microbiology


[Aims] Students learn the rudiments of experimental techniques for microbiology, immunology and related fields. [Contents] 1. Students learn the rudiments of experimental techniques for

microbiology, immunology and related fields; such as cell culture, ELISA, RT-PCR, real-time PCR, Western blotting, flow cytometry, immunostaining, and experiments using animals (mainly mice).

2. Students could select techniques among the above program with consultation.

Text/Materials/References etc. Protocols and suitable materials are available.

Method of evaluating performance By attendance to the basic technical course.

Comments Students should contact the following before registration. Prof.TAKADA [email protected]

37

Course Subject Basic Technical Courses in Dental Sciences: Periodontology and Endodontology


○ Keiichi SASAKI Eiji NEMOTO, And others

Credits 1

Day/time of classes Consult with learners Place Consult with learners


[Aims] Learning of required experimental skill in Periodontology, Endodontology and the related fields. [Contents] Learning of required experimental skill to research Periodontology, Endodontology and the related fields on a one-on-one coaching. 1.Cell culture 2. ELISA 3.RT-PCR and Real-time PCR 4.Western blotting 5. Flowcytometry 6.Basic technique in animal experiment (mouse and rat)

Text/Materials/References etc. Provide materials if needed


Comments Number of students may be limited. Students should contact the following before registration. Assoc. Prof. NEMOTO [email protected]

38

Course Subject Basic Technical Courses in Dental Sciences: Oral Molecular Bioregulation


○ Shunji SUGAWARA Toshinobu KUROISHI

Credits 1

Day/time of classes

Second semester/Mon. 4th period Place Laboratory of Oral Molecular

Bioregulation


[Aims] Master the basics of Western blotting, and utilized the skills in the research. [Contents]

1. Master the basic principles of Western blotting (Sugawara) 2. Learn the skills of Western blotting (Kuroishi) 3. Discuss the application of research (Sugawara and Kuroishi)

Text/Materials/References etc. None.

Method of evaluating performance By presence and report.

Comments Day/time of this class is flexible. Students should contact the following before registration. Prof.SUGAWARA [email protected]

39

Course Subject Basic Technical Courses in Dental Sciences: Division of Oral and Craniofacial Anatomy


○ Hiroyuki ICHIKAWA Tadasu SATO

Mitsuhiro KANO Credits 1



[Aims] To learn and understand the method for measurement of anatomical and histological data about sensory neurons in the tooth pulp and periodontal tissues [Contents] 1. Measure and software 2. Measurement of cell size of sensory neurons innervating the tooth

pulp 3. Measurement of the length of nerve fibers in the tooth and

periodontal tissues 4. Measurement of immunoreactive intensity in tooth pulp sensory

neurons 5. Estimation and investigation of errors in measurement statistical

analysis

Text/Materials/References etc. none


Comments Day/time of this class is flexible. Students should contact the following before registration. Prof.ICHIKAWA [email protected]

40

Course Subject Basic Technical Courses in Dental Sciences: Dental and Digital Forensics


○ Toshihiko SUZUKI

Credits 1

Day/time of classes

TBD – Please ask the instructor. Place TBD – Please ask the instructor.


[Aims] The aim of this course is to acquire the techniques to identify human skeleton.

[Contents]

Identification of human bones Bones of the vertebral column and the thorax Bones of the pectoral girdle and the upper limb Bones of the pelvis and the lower limb Basic structure of the skull Determination of sex of the skeleton Estimation of age at death in the skeleton


Textbooks are not specified. Other recommended readings will be provided in the course.


Grading will be based on participation and practical skills test.

Comments Students should contact the following before registration. Assoc. Prof. SUZUKI [email protected]

41

Course Subject Basic Technical Courses in Dental Sciences: [Oral Physiology]


○ Takashi TODA

Credits 1

Day/time of classes Consult with learners Place Laboratory of Oral Physiology


[Aims] 1. To learn the in vivo experimental methods of neurophysiology. 2. To understand the in vivo experimental methods for somatic sensation. 3. To understand the methodology of acute experiments of animals. [Contents] 1. Methodology of anesthesia of animals. 2. Methodology of animal preparations. 3. Methodology of single neuron recording with metal microelectrodes. 4. Methodology of numerical analyses of neural activities.



Comments Day/time of this class is flexible. Students should contact the following before registration. Assoc. Prof. TODA [email protected]

42

Course Subject Basic Technical Courses in Dental Sciences: Advanced Prosthetic Dentistry


○ Keiichi SASAKI Toru OGAWA Soshi HANAWA

Credits 1



[Aims] This course aims to learn the research methods with technical pro-cedures needed for performing your own research experiment. [Contents] 1. in vivo measurement

1) using a strain gauge and pressure-transducer 2) using a 3D load-measuring sensor installed in a

dental crown and implant. 3) using a pressure sensor sheet to measure the me-

chanical stress beneath a denture-base (Instructor: Keiichi Sasaki)

2. Measurement of the bone metabolic activity using a bone

Scintigraphy (Instructor: Toru Ogawa)

3. Measurement of the function with mastication and

swallowing 1) EMG (Electromyogram) of masticatory muscles 2) Measurement of tongue movement (Instructor: Toru Ogawa, Soshi Hanawa)

4. Prospective clinical study

(Instructor: Toru Ogawa) Text/Materials/References etc. Instruct in the beginning of the class.


Comments

Day/time and place of this class are flexible. Consult with instructors. Students should contact the following before registration. Prof.SASKI [email protected]

43

Course Subject Oral Biology Instructor (circle name of main Instructor)

Nobuhiro TAKAHASHI Takashi TODA Yasuyuki SASANO

○ Hiroyuki ICHIKAWA Credits 2

Day/time of classes First/Third semester Place TBA


[Aims] This subject aims to learn about basic dental science including anatomy, histology, physiology and biochemistry of cranio-oro-facial region, with scientific and logical thinking. [Contents] ・To learn about biochemical structure and function of body constituents

such as nucleic acid and protein. ・To learn about the oral cavity as an ecological system consisting of

host tissue (teeth, mucous, saliva etc) and parasite (microorganisms). (Prof. TAKAHASHI)

・To learn about neural mechanisms underlying oro-facial functions, such as feeding and articulation. (Associate Prof. TODA)

・To learn about histology and embryology of teeth and other cranio-oro-facial structures as well as histogenesis and regeneration of these organs, which provides a base for clinical regenerative medicine and dentistry. (Prof. SASANO)

・ To learn gross anatomy of human cranial and cervical structures. ・ To learn morphology and function of teeth and other intra-oral

structures (Prof. ICHIKAWA)



Comments

Details are subject to change. Students should contact the following before registration. Prof.ICHIKAWA [email protected]

44

Course Subject Oral Pathophysiology Instructor (circle name of main Instructor)

Minoru WAKAMORI Haruhiko TAKADA Shunji SUGAWARA

○ Hiroyuki KUMAMOTO Hisanori HORIUCHI Hozumi MOTOHASHI Credits 2

Day/time of classes Tuesday/3rd Place Not determined


[Aims] We provide multidisciplinary perspectives on a wide variety of oral diseases, including a pharmacological aspect, a microbiological aspect, an immunological aspect, a morphological aspect, and cell signaling. [Contents] Students attending the lecture first learn historical aspect of bacteriolo-

gy, especially oral bacteriology. Then, they should learn innate im-munity in oral mucosa in relation to pathogenesis of infectious dis-eases in oral cavity, especially periodontal diseases, with special ref-erence to up-to-date findings in the field. (Prof. Takada)

Learn host defense mechanism that is characteristic of oral mucosa, and

understand the immunologic characteristics in the expression of pathogenesis of the oral mucosal diseases. In addition, discuss the creation of prevention and treatment of the diseases. (Prof. Sugawara)

Molecular mechanism about regulation by low molecular weight GTP

binding protein associated with osteolysis inhibitor bisphosphonates is introduced. (Prof. Horiuchi)

Transcription regulatory mechanism associated with oncogenesis and

progression of oral cancer is introduced with lectures about mouse developmental engineering. (Prof. Motohashi)

Pathological characteristics of various kinds of oral and maxillofacial

disorders are introduced. (Prof. Kumamoto) Lecture and discussion on molecular mechanisms of oral sensations which monitor environmental conditions. (Prof. Wakamori)

Text/Materials/References etc. None specified

Method of evaluating performance Attendance and discussion


45

Course Subject Medical and Dental Biomaterials


○ Keiichi SASAKI Yukyo TAKADA Osamu SUZUKI Takashi GOTOH Mitsuo NIINOMI Credits 2



[Aims] Students learn the knowledge for biomaterials used widely in medicine dentistry, involving the physicochemincal, mechanical and biological properties necessary as biomaterials. [Contents] ・To learn about the knowledge research and development of future

biomaterials based upon comprehension of physicochemincal, mechanical and biological properties necessary as biomaterials used for restoration and reconstruction of stomatognathic system.

・To learn about the biomaterials for orofacial reconstruction and their

clinical use. (Prof. SASAKI)

・To learn about the biomaterials for restorative dentistry and their clinical use. (Assistant Prof. KOBAYASHI)

・To learn about the biomaterials for tissue regeneration and their clinical use. (Prof. SUZUKI)

・To learn about the ceramics as dental biomaterials. (Prof. GOTOH)

・To learn about titanium and titanium alloy as dental biomaterials. (Prof. NIINOMI)

Instruct in the beginning of the class.

Method of evaluating performance Instruct in the beginning of the class.

Comments


46

Course Subject Medical and Dental Device Science


○ Keiichi SASAKI Yukyo TAKADA

Credits 2



[Aims] This subject aims to learn about requirement for the medical and dental equipments and devices from the view point of mechanics and material science. [Contents] ・ To learn about necessary properties as the medical and dental

equipments and devices for reconstruction and maintenance of stomatognathic form and function in terms of mechanics, biomaterial science, biometrics and ergonomics.

・To learn about the requirement for the medical and dental equipments

and devices based on orofacial reconstruction. (Prof. SASAKI)

・To learn about the requirement for the medical and dental equipments

and devices based on restorative dentistry. (Lecturer SASAZAKI)



Comments


47

Course Subject Food Science Instructor (circle name of main Instructor)

○ Takeyoshi KOSEI Keiichi SASAKI NobuhiroTAKAHASHI

Credits 2

Day/time of classes

The 1st term, Tuesday, 3rd periods Place Consult with learners


[Aims] Aims are to learn the knowledge for research and development of functional foods, from the viewpoint of maintenance and promotion of oral health (such as prevention of dental caries and periodontal diseases) and functions. [Contents] To learn about food properties, based on nutritional science and biochemistry. ・To learn about the relationship between foods and dental caries from sugar metabolic activity of oral microbiota (dental plaque/oral biofilm), with research and development of non/low-cariogenic foods. (Prof. Takahashi, in April) ・To learn about the relationship between physical property of food and dental plaque, as the ecosystem of oral symbiotic microbes in the environment with saliva, in the aspect of molecular biology and biomechanics. (Prof. Koseki, in May) ・To learn about the relationship between texture of food and function of mastication and swallowing, and discusses the influence of eating upon the function of stomatognathic system. (Prof. Sasaki, in June)



Comments


48

Course Subject International Oral Health



Credits 2

Day/time of classes Consult with learners Place Seminar room of the dept.


The aims of this lecture are: To lea r n den t a l h ea lt h sys t em of J a pa n a s well a s ot h er cou n t r ies . To lea r n th e fr a m ework of globa l cooper a t ion in h ea lth field . Content of class:

・To learn about the health insurance systems in Japan and other

OECD countries.

・ To learn about the present state and future role of the Japanese social

insurance system.



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.OSAKA [email protected]

49

Course Subject Social Dentistry Instructor (circle name of main Instructor)

○ Takeyoshi KOSEKI Ken OSAKA

Credits 2

Day/time of classes

The 2nt term, Monday, 3rd periods Place Consult with learners


[Aims] Aims are to learn the knowledge in the field of dental-health economics, dental welfare, and politics of dental healthcare, and understand various issues of dental care and oral health management. [Contents] ・To learn about the prospects of dentistry through fact finding of the social problems among dental care and oral health, and lectures adequate cooperation of social welfare system and dental care, e.g. disclosing information of dental treatment (Prof. Koseki, in April and May). ・To learn about the current status and future perspective of social insurance system in Japan, especially the relation of nursing-care insurance system, dental care and oral health condition (Prof. Osaka, in June and July).



Comments


50

Course Subject Comprehensive Dentistry



Credits 2

Day/time of classes

First Term Monday /4th Period Place Office of Comprehensive

Dentistry


[Aims] To understand the outline of comprehensive dentistry and primary care. [Contents] To learn post graduate clinical education, team health care and general dental treatment in the comprehensive clinic.



Comments

Day/time and place of this class are flexible. Students should contact the following before registration. Prof.KIKUCHI [email protected]

51

Course Subject Oral Health Care for Children and Adolescents


○ Takeyoshi KOSEKI Kaoru IGARASHI

Satoshi FUKUMOTO Teruko YAMAMOTO

Credits 2

Day/time of classes

The 2nd term, Tuesday, 3rd periods Place Consult with learners


[Aims] Aims are to learn the etiology, prevention, and treatment of oral disorder and diseases in the developmental period throughout childhood and into adulthood, and to understand the importance of developing healthy mouth in their life. [Contents] ・To learn about the basics and clinical skills of hygiene management of oral health for developing healthy mouth (Prof. Koseki, in October). ・To learn about the guiding and management system of healthy dental arch and functional occlusion in developmental period (Prof. Fukumoto, in November). ・To learn about the etiology, prevention, and treatment of malocclusion and disorder of craniofacial development (Prof. Yamamoto, in December). ・ To learn about the various problems and medical and dental management of cleft lip and palate (Prof. Igarashi, in December).



Comments


52

Course Subject Oral Restoration Instructor (circle name of main Instructor)

○ Keiichi SASAKI Eiji NEMOTO Masahiro SAITO Masahiko KIKUCHI

Credits 2

Day/time of classes TBA(1st -4th semester) Place

TBA


[Aims] This subject aims to learn about restoration, reconstruction, rehabilitation and maintenance of the oral and craniomaxillofacial form and function damaged by various diseases and injury at the life stages after adulthood. [Contents] ・ To learn about pathological condition and pathogenesis of

periodontal disease, and prevention and management of periodontal disease. ( Assoc. Prof. NEMOTO)

・ To learn about prevention and management of oral diseases based on comprehension of the relationship among the oral diseases and systemic diseases. (Prof. KIKUCHI)

・ To learn about pathological condition and management of disorders accompanying with the loss of orofacial tissues including teeth, alveolar bone and soft tissues caused by dental caries, periodontal disease, inflammation and tumor in orafacila region. (Prof. SASAKI)

・ To learn about pathological condition and management of tooth decay caused by dental caries. (Prof. SAITO)



Comments


53

Course Subject Stomatognathic Function


○ Yoshinori HATTORIet al.

Credits 2

Day/time of classes Consult with leaners Place Laboratory of Aging & Geriatric

Dentistry


[Aims]

The stomatognathic system, which is comprised in digestive, respiratory, and sensory organs, participates in numerous functions. The aims of this class are to understand the functions of this system, and to learn the essential methods to study these functions.

[Contents]

1) Numerous functions of the stomatognathic system 2) Various methods to study stomatognathic functions



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.HATTORI [email protected]

54

Course Subject Special needs Dentistry Instructors (circle name of main Instructor)

○ Kazuko IGARI

Credits 2

Day/time of classes

October – December (Consult with learners) Place Consult with learners


Aims: To understand the special needs in dentistry for the person with mentally and/or physically disorders and learn the methods of oral health supports for them Contents:

1) Characteristic of oral findings and behavior of the person with mentally and/or physically disorders:

Mentally retardation, Cerebral palsy, Autistic disorder, Epilepsy, etc 2) Behavior management of person with special needs in dentistry 3) Eating and swallowing disorder and its rehabilitation in developmental stage


Method of Evaluating Performance By presence and reports

Comments

Day/time of classes are decided in consultation with learners Students should contact the following before registration. Senior Asst. Prof. IGARI [email protected]

55

Course Subject Geriatric Dentistry Instructor (circle name of main Instructor)

○ Yoshinori HATTORI

Credits 2


Dentistry


[Aims]

In spite of remarkable development of oral health care, the mean life-span of the tooth is still far shorter than that of the individuals in Japan. This may partly due to the contribution of age-specific risk factors of dental caries and periodontitis, both are the main causes of tooth loss in the elderly people. The aim of this class is to understand the age-specific risk factors of oral health.

. [Contents]

1) The current state of oral and dental health of Japanese elderly

population 2) The risk factors of oral and dental health in the stage of old age



Comments


56

Course Subject Dental Infection Control Instructor (circle name of main Instructor)

○ Keiichi SASAKI Hideaki ENDO

Credits 2

Day/time of classes

Consult with Hidetoshi SHIMAUCHI Place Division of Dental Infection

Control


[Aims] 1. To understand the hospital infection disease and its mechanisms, basic knowledge for prevention of hospital infection and specificity of dental infection control measures. 2. To obtain the necessary knowledge to offer safe dental treatment. [Contents] 1. Infection control dental seminar 1) Basic knowledge for infectious disease 2) Basis of infection control measures 3) Infection control measures for dentistry 2. Practice for standard precaution in dental hospital 3. Attendance at the designated lectures Designated lectures by faculty of Tohoku University Graduate School of Dentistry. 4. Attendance at the designated seminar, lectures or faculty development etc. Attendance at the "1" and "2" are required, and addition, students who take this course must select "3" or "4".


Method of evaluating performance By presence and reports.

Comments Students should contact with Dr. Endo before registration.

57

Course Subject Oral and Maxillofacial Reconstruction


○ Yasuyuki SASANO Keiichi SASAKI Tetsu TAKAHASHI Eiji MASAKI Osamu SUZUKI Credits 2



[Aims] This subject aims to learn about reconstruction of the oral and craniomaxillofacial complex from the aspect of cell and tissue biology, tissue engineering and clinical dental science. [Contents] ・ To learn about development and repair of the oral and craniomaxillofacial complex from the aspect of cell and tissue biology. (Prof. SASANO) ・To learn about reconstruction of the oral and craniomaxillofacial complex from the aspect of biomaterials science and tissue engineering. (Prof. SUZUKI) ・To learn about reconstruction of the oral and craniomaxillofacial complex from the aspect of clinical physiology and prosthodontics. (Prof. SASAKI) ・To learn about reconstruction of the oral and craniomaxillofacial complex from the aspect of oral and maxillofacial surgery. (Prof. TAKAHASHI) ・To learn about reconstruction of the oral and craniomaxillofacial complex from the aspect of anesthesiology. (Prof. MASAKI)



Comments

Details are subject to change Students should contact the following before registration. Prof.Yasuyuki SASANO [email protected]

58

8. Educational Goals and Class Plan by Subject (Doctoral Course)

59

Course Subject Lectures in Dental Sciences: Dental Pharmacology



Credits 3

Day/time of classes Monday / 1st Place Seminar Room in Lab. of

Pharmacol.


[Aims] This course is designed to help students understand membrane physiology. [Contents] Neurons convey fast neural information by virtue of electrical and chem-

ical signals. The chemical signals released from pre-synaptic mem-branes are converted into electrical signals by ligand-gated ion channels. Electrical signals are carried by transmembrane ion cur-rents, and result in changes in transmembrane voltage. Therefore, we will lecture on the following points.

1) Electrophysiological and molecular biological descriptions of ionic

channels and transporters Lecture on the Hodgkin-Huxley model and structural biology of ion channels

2) Channelopathy Lecture on the diseases caused by dysfunction of the channels

3) Channels and transporters as targets for drug therapy 4) New channels as receptors of oral sensations and signal amplifiers

A. TRPV1 channel and pain B. TRP channels as mechanosensors C. TRP channels as signal amplifiers





60

Course Subject Lectures in Dental Sciences: Oral Microbiology


○ Haruhiko TAKADA et al.

Credits 3

Day/time of classes Consult with students Place Consult with students


Aims Students could attend the lectures on the frontiers of oral science, especially oral microbial infections and host responses against the microbes, and learn up-to-date findings in the closely related scientific fields. Students might obtain useful information for their own research in PhD course. Contents 1. Selected lectures by scientists in Tohoku University Graduate School

of Dentistry. 2. Lectures in “Seminar on Immunology” organized by Tohoku

University Graduate School of Medicine. 3. Selected lectures in “Infection and Immunity” for undergraduate

students in Tohoku University School of Dentistry. 4. Other related special lectures. Students should select lectures among the above program (more than 4 hours, including lectures by Prof. Takada).


Resume and related materials are available on attending in some lectures.

Method of evaluating performance By attending and reports on demand.


61

Course Subject Lectures in Dental Sciences: Periodontology and Endodontology

Instructors (circle name of main Instructor)

○ Keiichi SASAKI Eiji NEMOTO And others

Credits 3



Aims Understanding 1) infectious diseases in endo-perio lesion and 2) host-parasite interaction associated between oral and systemic lesions. Understanding possible development of new therapy based on biological response and enhancing capabilities to gather information leading to new clinical dentistry. Contents 1. Seminar in periodontology and Endodontology (8 hrs) 1) Periodontitis and immune response (2 hrs) 2) Endodontitis and immune response (2 hrs) 3) Periodontal regeneration from the aspect of cellular biology (2hrs) 4) Periodontitis and systemic diseases (2hrs)

2. Assigned Seminar (more than 2 hrs x 6) Any special lectures related to dentistry conducted by faculty in department of dentistry

3. Any other assigned Seminar (more than 2 hrs x 6)

mandatory subject：content1 elective subject: content 2 or 3



Comments Day/time of this class is flexible. Students should contact the following before registration. Assoc. Prof. NEMOTO [email protected]

62

Course Subject Lectures in Dental Sciences: Oral Molecular Bioregulation



Credits 3

Day/time of classes

First semester/Mon. 1st and 2nd periods Place B4 Seminar Room (Building B)


Aims Understand the mechanisms of immune and inflammatory responses and oral defense. Contents 1. Learn about oral defense mechanism and the expression and

pathogenesis of oral diseases (Sugawara)

2. Learn about the mechanism of immune response and tolerance induction in oral mucosa (Kuroishi)




63

Course Subject Lectures in Dental Sciences: Oral and Craniofacial Anatomy


○ Tadasu SATO Mitsuhiro KANO Satoshi KAWAKAMI Tessei NAGAYAMA

Credits 3



Aims To learn and understand the advanced science research about neuronal degeneration and regeneration Contents 1. Morphological changes of neurons by their degeneration and

regeneration 2. Importance of neurotrophic factors for neuronal regeneration 3. Application of neurotrophic factors



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.ICHIKAWA [email protected]

64

Course Subject Lectures in Dental Sciences: Dental and Digital Forensics



Credits 3

Day/time of classes

TBD - Please ask the instructor. Place TBD - Please ask the instructor.


A: Course for dentists / dental care professionals

The aim of this lecture: This course is designed for dental professionals. In this course, students learn basic knowledge of method of personal identification using dental information.

Content of Class:

What is dental identification? Collecting the post-mortem information Collecting the ante-mortem information Matching and comparison of post- and ante- mortem information Dental identification in mass fatality incident

B: Course for non-dental professionals

The aim of this lecture: This course is designed for non-dental professionals. In this course, students learn basic knowledge of method to differentiate human from non-human bones and teeth.

Content of Class: Human or non-human? Basic comparative anatomy of mammalian skeleton Basic comparative anatomy of mammalian dentition


Textbooks are not specified. Other recommended readings will be provided in the lectures.

Method of evaluating performance Grading will be based on participation and final report.


65

Course Subject Lectures in Dental Sciences: Oral Physiology


○ Takashi TODA

Credits 3



The aim of this lecture:

1. To understand the basic neurophysiology. 2. To understand the sensory physiology. 3. To understand the neurophysiology on motor system. Contents of Class: 1. Outline of neurophysiology 2. Somatic sensation 3. Oral sensation 4. Pain and analgesia 5. Neural mechanisms of mastication 6. Periodontal sensation




66

Course Subject Lectures in Dental Sciences: Advanced Prosthetic Dentistry

Instructor (○:responsible instructor)

○ Keiichi SASAKI Toru OGAWA

Credits 3

Day/time of classes

the 1st term, Tuesday, 1st -2nd periods Place The office of Advanced Prosthetic

Dentistry


【Aims】

To learn basic research, clinical study and state-of-the-art study in the prosthetic dental field. This course provides with the information of these outline.

【Content】

1. Current trends and issues of the prosthetic dentistry (Instructor: Keiichi Sasaki)

2. Biomaterial - biological interface (Instructor: Keiichi Sasaki) 3. Biomechanical - biological interface (Instructor: Keiichi Sasaki) 4. Relationship between the function of mastication and swallowing (Instructor: Keiichi Sasaki) 5. Evidence in the prosthodontics (Instructor: Toru Ogawa)

Text/Materials/References etc. Ask the corresponding instructor.

Method of evaluating performance Attendance of the class and a report of assignment.

Comments

In consultation with students, time of classes can be changed. Students should contact the following before registration. Prof.SASKI [email protected]

67

Course Subject Lectures in Dental Sciences: Aging and Geriatric Dentistry



Credits 3


Dentistry



1. To understand the risk factors for the deterioration of the oral health status of the elderly population

2. To argue the strategy for promoting geriatric oral health Content of Class:

1. Oral health status of the Japanese elderly population 2. Risk factors for the deterioration of geriatric oral health status 3. The strategy for promoting oral health in the elderly population


Method of Evaluating Performance By presence and report

Comments


68

Course Subject Lectures in Dental Sciences:Comprehensive Dentistry



Credits 3

Day/time of classes

Second Term Monday /1st & 2nd Period Place Office of Comprehensive

Dentistry


The aim of this lecture: To learn the relationship between oral status and systemic health for understanding holistic dental care. Content of Class: 1. Oral hygiene and quality of life 2. Eating function and nutrition 3. Mastication and physical function 4. Mastication and mental health 5. Oral hygiene and systemic diseases




69

Course Subject Lectures in Dental Sciences: Dental Biomaterials



Credits 3

Day/time of classes

The first and second hours on Wednesday in the first semester

Place Div. of dental biomaterials on the fifth floor in the basic research (Building A)


Aim

The aim is to understand basic knowledge of metallic materials used for dentistry and to equip its applied skill.

Contents Overview of titanium and titanium alloys Titanium and titanium alloys as biomaterials Biocompatibility of titanium alloys Corrosion resistance of titanium alloys Dental casting of titanium alloys Titanium alloys for a dental CAD/CAM Development of new titanium alloys for a dental CAD/CAM Application of magnets Dental magnetic attachments Corrosion resistance and biocompatibility of magnetic alloys



Comments

After consultation with learners, time and day of starting the course will be adjusted. Students should contact the following before registration. Assoc. Prof.TAKADA [email protected]

70

Course Subject Lectures in Dental Science:Operative Dentistry


○ Masahiro SAITO

Credits 3

Day/time of classes Consult with learners Place Staff Room of Division of

Operative Dentistry


The aim of this lecture: 1. Understanding of the dental treatment for patient of systemic

disease 2. Understanding of the periodontal ligament regeneration therapy

Content of Class:

1. Systemic disease and operative dentistry 1) Basic knowledge of connective tissue disorder accompanied by dental

disease. 2) Evaluation of periodontal tissue using disease animal model.

3. Regeration therapy of periodontal ligament 4. 1) Basic knowledge of regeneration therapy 2) Basic knowledge and clinical trial of the periodontal ligament regeneration therapy.



Comments

Day/time of this class is flexible Students should contact the following before registration. Prof.SAITO [email protected]

71

Course Subject Lectures in Dental Sciences: Molecular and Regenerative Prosthodontics


○ Hiroshi EGUSA

Credits 3

Day/time of classes To be announced Place

Seminar room of the Division of Molecular and Regenerative Prosthodontics


[Aims]

To learn the basic knowledge for molecular and regenerative prosthodontics and to understand biology-based prosthodontic treatment approach.

[Contents]

Lectures 1. Increasing diversity in prosthodontic research 2. Prosthodontics as science 3. Impact of biotechnology on current and future prosthodontics 4. Stem cells in dentistry 5. Application of regenerative medicine to fixed prosthodontics


Egusa H. et al.: Stem cells in dentistry -Part I: stem cell sources & Part II: Clinical applications. Journal of Prosthodontic Research. 2012.


Comments

Applicants should contact with Prof. Egusa before registration. Students should contact the following before registration. Prof.EGUSA [email protected]

72

Course Subject Lectures in Dental Sciences: Preventive Dentistry


○ Takeyoshi KOSEKI Ryouichi HOSOKAWA Naoko TANDA

Hanako SUENAGA Masaki SUGAZAKI Credits 3

Day/time of classes

Second Term Monday /3rd period Place Laboratory of Preventive

Dentistry

Aims & objectives of Class

Aims and objectives: To learn the dental practice and oral health guidance of preventive dentistry, to improve and promote public oral health to ensure the healthy life style among whole nations. Content of class: 1. Study various problems and effective managements of the activities of

oral health promotion in local communities. 2. Study oral environmental factors and preventive oral diseases in the

elderly.



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof. KOSEKI [email protected]

73

Course Subject Lectures in Dental Sciences: Pediatric Dentistry



Credits 3

Day/time of classes

Jun, Oct (Thu 1st and 2nd period) Place suspense


[Purpose] Purpose of this course is to understand the pediatric dental disorder (phenotypes, frequency and treatment) and regeneration medicine in the field of dental research. [Contents] First semester (Jun) 1) Physical and psychological development of children necessary for the

pediatric dental treatment. 2) Genetic disorder associated with craniofacial development.

Second semester (Oct) 1) Over view of tooth regeneration study.



Comments

Please confirm the schedule of course. Students should contact the following before registration. Prof.FUKUMOTO [email protected]

74

Course Subject Lectures in Dental Sciences: Orthodontics and Dentofacial Orthopedics



Credits 3

Day/time of classes

Instructors will contact the graduate students. Place Instructors will contact the

graduate students.


[Aims] To understand the current clinical and basic research of orthodontics by leading-edge information of diagnosis and treatment of malocclusion. To understand the basic knowledge of bone metabolism in maxillofacial growth and tooth movement. [Content of Class] 1. Seminar series (8 hours) 1) Biological reaction and mechanism of tooth movement (2 hours) 2) Orthodontic diagnosis and cephalometric analysis (2 hours) 3) Analysis of stomatognathic function on orthodontic treatment (2 hours) 4) Orthodontic treatment of patients with congenital anomaly (2 hours) 2. Attendance at the designated lectures (2 hours × 6 or more) Designated lectures by faculty of Tohoku University Graduate School of Dentistry. 3. Attendance at the designated seminars or lectures etc. (2hours × 6 or more) Attendance at the “1” is required, and in addition, graduate students who take this course must select the “2” or “3”.



Method of Evaluating Performance Based on attendances of classes and reports

Comments

Graduate students who take this course are required to contact their instructor, Teruko Takano-Yamamoto, to attend the classes. Students should contact the following before registration. Prof. YAMAMOTO [email protected]

75

Course Subject Lectures in Dental Sciences: Oral Dysfunction Science



Credits 3

Day/time of classes

The 2nd semester, Tuesday, The 1st and 2nd classes

Place Seminar & Training Room of Oral Dysfunction Science



1. To understand the latest researches performed in this laboratory and those on the relevant issues from other laboratories in the world.

2. To obtain useful information for your own research. Content of Class: 1. Periodontal tissue responses to the external force (Instructors: Kaoru Igarashi and others) 2. Biological rhythms and orthodontic treatment (Instructor: Kaoru Igarashi) 3. Assigned lectures, seminars and others



Comments


76

Course Subject Lectures in Dental Sciences: International Oral Health



Credits 3

Day/time of classes

First Term Thursday /1-2nd period Place The seminar room of the

department


The aims of this lecture are: To learn dental health system of Japan as well as other countries. To learn the framework of global cooperation in health field.

Content of class: ・ To comprehend the needs of international collaboration. ・ To learn about the appropriate technology in cooperation with

developing countries. ・ To learn about the present state and future role of the Japanese

social insurance system.




77

Course Subject Lectures in Dental Sciences: Oral Pathology



Credits 3

Day/time of classes

First semester Fri 1,2 Place Division of Oral Pathology


[Objective] Specific and synthetic lectures about oral cancer and odontogenic tumor are done. [Contents] 1. Oral cancer: Precancerous lesions, epidemiology, etiology, morphology, diagnosis, and therapy. 2. Odontogenic tumor: Tooth development, classification, morphology, diagnosis, and molecular aspect.




78

Course Subject Lectures in Dental Sciences: Oral Diagnosis



Credits 3

Day/time of classes

Fridays, 3rd and 4th periods Place Laboratory of Oral Diagnosis


[Aim] To acquire knowledge to diagnose a disorder based on scientific evidence and logical thinking. [Content] ・To teach clinical diagnosis for oral and maxillofacial diseases based on the patient’s history, clinical findings, laboratory data and diagnostic imaging (lecture).


Oral Diagnosis and Radiology (5th Edition) (published in our department)


Comments

Day/time of classes is subject to change by consulting with the students. Students should contact the following before registration. Prof. Takashi SASANO [email protected]

79

Course Subject Lectures in Dental Sciences:Oral and Maxillofacial Surgery


○ Tetsu TAKAHASHI Masatoshi CHIBA Shiro MORI Kensuke YAMAUCHI Wataru HASHIMOTO Credits 3

Day/time of classes

Friday, 1st and 2nd hour Second semester Place



【Aims】 To learn the basic knowledge of morphology, pathophysiology and treatment for oral and maxillofacial regions, and further learn materials and methods for basic and clinical research for oral and maxillofacial surgery. Lastly, brush up the cutting edge of research 【Contents】 1. Current concept of Oral and Maxillofacial Surgery 2. Congenital anormalies and doformities in oral and maxillofacial area 3. Inflammation and trauma in oral and maxillofacial region 4. Tumors in oral and maxillofacial region 5. Temporomandibular diseases 6. Morphological and functional reconstruction in oral and maxillofacial

region 7. Reconstruction using dental implants in oral and maxillofacial region


Method of Evaluating Performance


Comments


80

Course Subject Lectures in Dental Sciences: Dento-oral Anesthesiology


○ Eiji MASAKI Kentaro MIZUTA Kanta KIDO

Credits 3

Day/time of classes

The second semester Friday, the 1st・

2nd period Place



【Aim】 To understand basic and clinical science for conducting the research of dento-oral anesthesiology. 【Contents】 1. Introduction of anesthesiology 2. General management of patient 3. Local anesthesia 4. Sedation for dental treatment 5. General anesthesia 6. Co-existing disease and its problems in anesthesiology 7. Diagnosis and treatment of pain in oro-facial area 8. Management of complications during dental treatment 9. Cardio-pulmonary resuscitation



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.MASAKI [email protected]

81

Course Subject Lectures in Dental Sciences: Craniofacial Development and Regeneration


○ Yasuyuki SASANO

Credits 3



Aim of this course: To introduce scientific research in tissue biology of bones and teeth. Content of the class: 1. Introduction of research conducted by the lecturer. 2. Review of recent information in literature.



Comments

Day/time of this class is flexible Students should contact the following before registration. Prof.Yasuyuki SASANO [email protected]

82

Course Subject Lectures in Dental Sciences: Craniofacial Function Engineering



Credits 3





1. To understand the biological reaction of bone substitute materials such as octacalcium phosphate (OCP).

2. To understand the role of stem cells in relation to bone regeneration. 3. To understand the methodology of tissue engineering. Content of class: 1. Methodology of tissue engineering 2. Design of biomaterials 3. Cells and biomaterials 4. Drug delivery system with biomaterials



Comments


83

Course Subject Lectures in Dental Sciences: Division of Community Oral Health Science



Credits 3

Day/time of classes

the 1st term, Tuesday, 1st -2nd periods Place Laboratory of Community Oral

Health Science



The aging of Japanese population was rapidly brought about by a combination of low fertility and high life expectancies. Under this social background, the lectures aim to learn and understand the advanced science research about dental health support system for community.

Content of Class:

1. Review of the community dental health support 2. Oral health care and quality of life 3. Strategy for oral health promotion in the aging community



Comments


84

Course Subject Lectures in Dental Sciences: Oral Cancer Therapeutics


○ Hisanori HORIUCHI Ryutaro SHIRAKAWA

Credits 3

Day/time of classes

Consult with Hisanori Horiuchi Place

Department of Molecular and Cellular Biology, Institute of Development, Aging and Cancer


The aim of this lecture: To understand the molecular mechanism of cellular processes such as cell proliferation and movement in oral inflammation and cancer Content of Class: Lecture on the molecular mechanisms of intracellular signal transduction.



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.HORIUCHI [email protected]

85

Course Subject Lectures in Dental Sciences: Molecular Oral Oncology



Credits 3

Day/time of classes




The aim of this lecture: To understand the regulatory mechanisms of gene expression in response to oral inflammation and mechanical stress Content of Class: Lecture on the molecular mechanisms of stress-activated gene expression



Comments


86

Course Subject Lectures in Dental Scienc-es: Bio-Dental Engineering


○ Shinji KAMAKURA

Credits 3

Day/time of classes

Consult with registered participants Place

Room No. 201, Building No.5 The Graduate School of Medicine’s

campus and others


Aims

To learn various biomaterials using in the field of dentistry and oral surgery and

relationship between organism and these materials

To explain the latest regenerative medicine on dental field and related new

materials

Contents

Bone regenerative materials and so on



The evaluation is performed based on attendance at lectures

and scores on examination.

Comments

Opening hours and place of the class will be altered in

accordance with consulting with participants.

Students should contact the following before registration. Prof. KAMAKURA [email protected]

87

Course Subject Lectures in Dental Sciences: Intractable Diseases and Immunology



Credits 3



[Aim] To understand the Cutting-edge research in immunology. [Contents]

1. Discussion in the seminar. (To be announced)



Comments


88

Course Subject Seminars in Dental Sciences: Division of Oral Ecology and Biochemistry


Nobuhiro TAKAHASHI ○ Takuichi SATO Jumpei WASHIO Gen MAYANAGI Yuki ABIKO Credits 2


Biochemistry


The aim of this exercise lesson class is to learn current topics on oral ecosystem, oral biofilm and oral diseases (such as dental caries, periodontal diseases and halitosis), in order to encourage the research activities performed by students in the Division of Oral Ecology and Biochemistry. Students who take this class may attend the weekly research seminar in the Division of Oral Ecology and Biochemistry, and then they may biannually perform the presentations of the progress reports on their own research activities.




89

Course Subject Seminars in Dental Sciences: Dental Pharmacology



Credits 2

Day/time of classes Monday / 3rd Place Seminar Room in Lab. of

Pharmacol.


[Aims & Contents] This seminar is designed to help students accumulate knowledge about signal transmission and intracellular signal transduction through the class presentation. Before the class presentation, students need to read some articles which are related to their own thesis works.



The largest part of the evaluation will be based on active participation in class activities and class presentations.


90

Course Subject Seminars in Dental Sciences: Oral Microbiology



Credits 2

Day/time of classes

Thursday 16:00～18:00 Place A3 seminar room


Aims Students read up-to-date scientific articles in microbiology, immunology and related fields, and explain the findings in the reports for attendants. Students should also attend the discussion on the reports presented by other attendants. Through these trainings students could master how to explore useful information and obtain skill to present scientific findings and to discuss on scientific theory and hypothesis. Contents 1. Students should read papers published recently in high-grade

journals in microbiology, immunology and related fields, and explain the findings in the reports for attendants.

2. Students should present papers more than two times. 3. Students also attend the discussion on the papers presented by othe

attendants.

Text/Materials/References etc. Materials prepared by presenters are available.


By presentation and discussion. (Students should attend the seminars)


91

Course Subject Seminars in Dental Sciences: Periodontology and Endodontology



Credits 2

Day/time of classes

1st and latter semester Every Thursday (16:00~17:00)

Place Conference room in Division of Periodontology &Endodontology


Aims Developing an ability to comprehend international scientific paper regarding basic science of Endodontology, Periodontology and the related fields including bacteriology, immunology, and regenerative medicine. Enhancing of capacity gathering useful information and providing comprehensive yet concise commentaries on the topics. Contents This exercise is prepared for a graduate student and post-doctoral researcher. Article about the background of the study of each participant or the experimental method are discussed. The student attending a lecture can acquire the power to read and understand an English article and summarize the content in more by participating in this. In addition, The ability as the researcher is improved by up-date the latest information and participating in discussion. More than 30 hours through 1st and latter semester is required for the student.


The person in charge makes a document every time and distributes it.

Method of Evaluating Performance Evaluating by presentation contents and attendance.

Comments The attendance applicant talk with main instructo. Students should contact the following before registration. Assoc. Prof. NEMOTO [email protected]

92

Course Subject Seminars in Dental Sciences: Oral Molecular Bioregulation



Credits 2

Day/time of classes

First semester/Thu. 5th period Place B4 Seminar Room (Building B)


Aims By reading the English papers related to the study of Oral Molecular Bioregulation and by presenting and discussing its contents, you will develop the ability to understand the study, evaluate the paper and take advantage of your research. Contents In addition to participating in the debate to attend the meeting of our laboratory held on every Thursdays, you will introduce English research papers as a presenter.




93

Course Subject Seminars in Dental Sciences: Oral and Craniofacial Anatomy



Credits 2

Day/time of classes

Second semester Consult with learners Place Consult with learners


Aims To learn and understand the recent data about nociceptive transmission of oral and craniofacial structures Contents 1. Reading papers about nociceptive transmission of oral and

craniofacial structures 2. Presentation of the papers 3. Discussion about the subject of the papers




94

Course Subject Seminars in Dental Sciences: Dental and Digital Forensics



Credits 2

Day/time of classes



A. Course for dentists / dental care professionals

The aim: This course is designed for dental professionals. In this course, students learn fundamental methods of dental identification through the experience of filling the Japanese DVI (Disaster Victim Identification) forms on some actual cases of forensic autopsies.

Content of Class:

Postmortem dental examination Taking dental photographs Reconstruction of the ante-mortem dental status from the records Matching and comparison

Students are required to have reading ability in Japanese in order to read medical records written in Japanese.

B: Course for non-dental professionals

The aim: This course aims to make a fundamental understanding of forensic identification of human and non-human bones through intensive reading of the scientific literatures

Content of Class:

To obtain skills on reading scientific papers or textbooks on specialized areas



Method of evaluating performance Grading will be based on participation and final report.


95

Course Subject Seminars in Dental Sciences: Oral Physiology


○ Takashi TODA

Credits 2



The aim of this seminar:

1. To understand the neurophysiology of somethesia. 2. To understand the neurophysiology of mastication. Contents of Class: 1. Somatic sensation 2. Oral sensation 3. Gustatory sensation 4. Pain and analgesia 5. Motor neurophysiology 6. Mastication 7. Periodontal sensation




96

Course Subject Seminars in Dental Sciences: Advanced Prosthetic Dentistry

Instructor (○: responsible instructor)


Credits 2

Day/time of classes

The 1st term Tuesday, 3rd period Place The office of Advanced Prosthetic

Dentistry


【Aims】 Learn the research methods with technical procedure for performing

own research experiment. 【Content】

1. Biomechanical study in prosthodontics (Instructor: Keiichi Sasaki) ① Biomechanics of jaw bone, temporomandibular joint and

dentition ② Biomechanics of prostheses ③ In vivo measurement ④ Analysis by finite elemental model

2. Biomaterial-biological reaction in Prosthodontics

(Instructor: Keiichi Sasaki) ① Regulation of biological reaction by biomaterial

- Self-organization - Control of biological reaction - Mechanical adaptability

② Surface reforming/modification of biomaterial ③ Development into new biomaterial

3. Study about function of mastication and swallowing (Instructor: Keiichi Sasaki)

4. Prospective clinical study (Instructor: Toru Ogawa)


Method of evaluating performance Attendance of the class and a report of assignment.

Comments


97

Course Subject Seminars in Dental Sciences: Aging and Geriatric Dentistry


○ Takahisa MURAKAMI

Credits 2


Dentistry; Hanamaki, Iwate



To learn the theory and practice of clinical epidemiology through the participation in a longitudinal cohort study (the Ohasama Study).

Content of Class:

Lecture on the mutual interrelation between the oral and general health conditions Lecture on the history, aim, and outcome of the Ohasama Study Participation in the Ohasama Study




98

Course Subject Seminars in Dental Sciences:Comprehensive Dentistry



Credits 2

Day/time of classes

Second Term Monday / 3rd Period Place Office of Comprehensive

Dentistry


The aim of this lecture: To understand the educational method and role of comprehensive dentistry and primary care. Content of Class: To learn the outline of pre and post graduate clinical education and comprehensive dental care in the comprehensive clinic.




99

Course Subject Seminars in Dental Sciences: Dental Biomaterials



Credits 2

Day/time of classes

Consecutive three days (all day) in the first or last semester



Aim

The aim is to acquire the fundamental observation methods and elemental analyses that are necessary to study biomaterials, using a scanning electron microscope (SEM) and an electron probe X-ray microanalyzer (EPMA), respectively.

Contents

Principle of a scanning electron microscope Preparation of specimens Observation methods Principle of an electron probe X-ray microanalyzer Preparation of specimens Elemental analysis methods Qualitative analysis

Quantitative analysis



Comments

Learners must participate in the Experimental Technical Course (Dental Biomaterials). The lecture days will be adjusted after consultation with the learners. (Presence in all day is necessary on lecture days.) Students should contact the following before registration. Assoc. Prof.TAKADA [email protected]

100

Course Subject Seminars in Dental Science:Operative Dentistry


○ Masahiro SAITO

Credits 2

Day/time of classes Consult with learners Place Laboratory of Division of

Operative Dentistry



Basic understanding of pathology and treatment regarding cardiovascular disease associated with apical periodontitis and periodontitis

Content of Class: 1. Basic understanding of cardiovascular disease

1) Understanding of aorta including anatomy and biochemistry 2) Understanding of the molecular pathogenesis of arterial disease 3) Basic understanding of clinical treatment for arterial disease

2. Dental treatment of cardiovascular disease

1) Effect of cardiovascular disease on apical periodontitis and periodontitis

2) Basic understanding of conservative dentistry for cardiovascular disease 3) Clinical treatment of conservative dentistry for cardiovascular disease



Comments

Day/time of this class flexible Students should contact the following before registration. Prof.SAITO [email protected]

101

Course Subject Seminars in Dental Sciences: Molecular and Regenerative Prosthodontics


○ Hiroshi EGUSA

Credits 2

Day/time of classes To be announced Place

Seminar room of the Division of Molecular and Regenerative Prosthodontics


[Aims]

To increase technical knowledge for molecular and regenerative prosthodontics and to understand concepts of the biology-driven prosthodontics.

[Contents]

1. Participating in our weekly Journal Club and lab meeting. 2. Presentation and discussion in the Journal Club.

Text/Materials/References etc. Articles will be assigned for the Journal Club.


Attendance records and a proactive approach in their presentation/discussion.

Comments

Applicants should contact with Prof. Egusa before registration. Students should contact the following before registration. Prof.EGUSA [email protected]

102

Course Subject Seminars in Dental Sciences: Preventive Dentistry


○ Takeyoshi KOSEKI Naoko TANDA Ryouichi HOSOKAWA Hanako SUENAGA Masaki SUGAZAKI Credits 2

Day/time of classes


Dentistry

Aims & objectives of Class

The aims and objectives: To learn the skills for providing the motivation toward the oral health in the social activity of preventive dentistry. In this class, we focus on the effect of oral malodor measuring as the motivational tool of oral health. Content of class: 1. Basics of oral malodor measurements 2. Application of oral malodor measurements 3. Activity of oral health promotion and education with oral malodor

measurement as a motivational tool.



Comments


103

Course Subject Seminars in Dental Sciences: Pediatric Dentistry



Credits 2

Day/time of classes

Jun, Oct (Thu 3rd period) Place suspense


[Purpose] To predict tooth eruption and occlusional development, and evaluate the feeding and swelling of children, student who take the course study the basic knowledge and evaluation technique in pediatric dentistry. [Contents] First semester (Jun) 1) Diagnosis of tooth anormaly. 2) Evaluation of primary and mixed dentition, and prediction of

permanent dentition.

Second semester (Oct) 1) Evaluation of feeding and swelling in developmental stages. 2) Dysphagia rehabilitation.


Method of evaluating performance Attendance record and reports.

Comments


104

Course Subject Seminars in Dental Sciences: Orthodontics and Dentofacial Orthopedics



Credits 2

Day/time of classes Wednesday 17:00 Place Department of Orthodontics


Purpose The purpose of this course is to be able to obtain the ability to understand, discuss, objectively evaluate, and review the content of the research, and to search information for graduate student’s clinic and research of current principles of orthodontics and recent English articles related to the tooth movement by EBM (evidence-based medicine). Content This course is a Journal Club of discussing diagnosis and treatment technique related to the field of orthodontics. Graduate students should present the recent and high-level English article to the participants. Especially, the graduate student must evaluate and report the validity of materials and methods, discussion of the results obtained by the author, and basic and clinical significance of the study. In addition, when the other graduate student is presenting, the student must aggressively participate during the discussion, and progress one’s research ability of clinical orthodontics.

Text/Materials/References etc. Instructor will pass the hand outs during the course

Method of evaluating performance Quality of the presentation, reports and attendance rate

Comments

Students must report and discuss with Dr.Yamamoto prior to taking the course. There may be a change in the schedule. Students should contact the following before registration. Prof. YAMAMOTO [email protected]

105

Course Subject Seminars in Dental Sciences: Oral Dysfunction Science



Credits 2

Day/time of classes

The 1st semester, Wednesday, The 5th class Place Seminar & Training Room of

Oral Dysfunction Science



1. To understand the consensus and controversy on the diagnosis and treatment of malocclusion through reading around selected articles and books.

2. To get ability to objectively evaluate papers. Content of Class: Literature reviews in the field of malocclusion and related issues


Assigned articles and textbooks on malocclusion (The reading list will be provided.)

Method of evaluating performance By presence and report (summary of the papers)

Comments


106

Course Subject Seminars in Dental Sciences: International Oral Health



Credits 2

Day/time of classes

First Term Thursday /3rd period Place The seminar room of the

department


The aims of this lecture are: To learn dental health system of Japan as well as other countries. To learn the framework of global cooperation in health field.

Content of class: ・ To comprehend the indicators in global oral health situation. ・ To analyze the data on health of Japan and other OECD countries. ・ To learn about the health inequality of oral health in Japan and the

world.




107

Course Subject Seminars in Dental Sciences: Oral Pathology



Credits 2

Day/time of classes

First semester Fri 3 Place Division of Oral Pathology


[Objective] Autopsy cases are observed, and association of the oral lesion is learned. [Contents] Macroscopic and microscopic observation of autopsy cases is exercised , and various organs and tissues, containing the oral cavity, are examined.




108

Course Subject Seminars in Dental Sciences: Oral Diagnosis



Credits 2

Day/time of classes

Mondays～Fridays, 1st and 2nd periods Place

Mainly at Tohoku University Hospital Oral Diagnosis outpatient ambulatory


[Aim] Learn the method of oral diagnosis based on knowledge from scientific evidence and logical thinking. [Content] ・Teach diagnostic imaging for oral and maxillofacial diseases focusing on MRI, CT and US in clinical practice. ・Teach diagnosis methods of oral disease and planning treatment course in clinical practice.




Comments

Lecture will be held with residents. Day/time of classes is subject to change by consulting with the students. Students should contact the following before registration. Prof. Takashi SASANO [email protected]

109

Course Subject Seminars in Dental Sciences: Oral and Maxillofacial Surgery


○ Tetsu TAKAHASHI Shiro MORI Kensuke YAMAUCHI Masatoshi CHIBA Keiko MATSUI Credits 2

Day/time of classes

Friday, 3rd hour Second semester Place



【Aims】 To extract the subject for oral and maxillofacial surgery, to learn the basic knowledge and materials and methods for planning and performing of front line researches for solution and enforcement of it. 【Contents】 1. To learn clinical Anatomy of oral and maxillofacial region 2. To learn functions and their evaluation in oral and maxillofacial region 3. To learn artificial materials for reconstruction of oral and maxillofacial region 4. To learn method of reconstruction, clinical aspects, and researches on hard

tissue of oral and maxillofacial surgery 5. To learn method of reconstruction, clinical aspects, and researches on soft

tissue of oral and maxillofacial surgery 6. To learn basic researches on regenerative medicine 7. To learn clinical application of regenerative medicine to oral and maxillofacial

region



Comments Students should contact the following before registration. Prof.Tetsu TAKAHASHI [email protected]

110

Course Subject Seminars in Dental Sciences: Dento-oral Anesthesiology



Credits 2

Day/time of classes

The second semester Friday, the 3rd period Place



【Aim】 To practice clinical anesthesia 【Contents】 1. Preoperative evaluation of patients 2. Patient monitor and its interpretation 3. Sedation for dental treatment 4. Induction and maintenance of general anesthesia 5. Postoperative anesthetic management



Comments


111

Course Subject Seminars in Dental Sciences: Craniofacial Development and Regeneration



Credits 2


Development and Regeneration


The aims of this lecture: To understand the methodology of tissue biology through studying the latest research articles published in the international journals. This course is the common class with the seminars in Dental Sciences: Craniofacial Function Engineering Content of class: 1. Study of the research articles 2. Study of the structure of the articles 3. Study of the method of presentation and discussion in the researches



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.Yasuyuki SASANO [email protected]

112

Course Subject Seminars in Dental Sciences: Craniofacial Function Engineering



Credits 2




The aims of this lecture: To understand the methodology of tissue engineering through studying the latest research articles published in the international journals. This course is the common class with the seminars in Dental Sciences: Craniofacial Development and Regeneration. Content of class: 1. Study of the research articles 2. Study of the structure of the articles 3. Study of the method of presentation and discussion in the researches



Comments


113

Course Subject Seminars in Dental Sciences: Division of Community Oral Health Science



Credits 2

Day/time of classes

the 1st term, Tuesday, 3rd periods Place Laboratory of Community Oral

Health Science


The aim:

To understand the methodology of community oral health science and the related field including epidemiology, bacteriology and neurology, through studying the latest research articles published in the international journals.

Content of Class:

1. To read articles about oral and general health promotion 2. To make the concise summary of the article 3. To present the summary of article 4. To discuss about the subject of the article



Comments


114

Course Subject Seminars in Dental Sciences: Molecular Pathogenesis of Oral Tumor


○ Hozumi MOTOHASHI Hisanori HORIUCHI Ryutaro SHIRAKAWA

Credits 2

Day/time of classes

Consult with Hozumi Motohashi Place seminar room of Institute of

Development, Aging and Cancer


The aim: To understand the front lines of various fields of basic bioscience by listening to the lectures by seminar speakers Content of Class: Seminars of basic bioscience at Institute of Development, Aging and Cancer



Comments


115

Course Subject Seminars in Dental Sci-ences: Bio-Dental Engi-neering


○ Shinji KAMAKURA

Credits 2

Day/time of classes

The first semester Tuesday 8:50~12:00 Place Laboratory of Bone Regenerative



Aims

After perusing the highly cited and the latest manuscripts in English concerning

about Bio-Dental Engineering, draw up the abstracts and plainly explain the

content.

Present and make a report of content and progress of your own research.

To aim to acquire the undermentioned competence of presentation and

discussion through these exertion.

Search and obtain useful information from manuscripts

Explain and discuss the contents of your own research

Contents

Journal club concerning about Bio-Dental Engineering and related fields

To present and make a report of content and progress of your own research



The evaluation is performed based on the submitted reports

(abstracts of manuscripts) and oral presentation.

Comments

Opening hours and place of the class will be altered in

accordance with consulting with participants.

Students should contact the following before registration. Prof. KAMAKURA [email protected]

116

Course Subject

Seminars in Dental Sciences: Intractable Diseases and Immunobiology



Credits 2



[Aim] To obtain the knowledge and methods for research in immunology. [Contents]

1. Presentation in our Journal club.

2. Discussion in the seminar. (To be announced)



Comments


117

Course Subject Technical Courses in Dental Sciences: Oral Ecology and Biochemistry


Nobuhiro TAKAHASHI ○ Takuichi SATO Jumpei WASHIO Gen MAYANAGI Yuki ABIKO Credits 2


Biochemistry


The aim of this training course is to obtain and master the experimental technique on oral ecosystem, oral biofilm and oral diseases (e.g., dental caries, periodontal diseases and halitosis), in order to perform experiments in the Division of Oral Ecology and Biochemistry. Students who take this course may learn basic biochemical methods (e.g., spectrophotometric and enzymatic analyses, and HPLC－based analysis for carboxylic acids), and molecular biological methods (e.g., polymerase chain reaction, random cloning and DNA sequencing). Furthermore, students may learn advanced experimental technique on oral plaque biofilm (e.g., culture, isolation and identification of oral microorganisms, and metabolomics of oral biofilm), utilizing an anaerobic glove box and a capillary electrophoresis equipped with a mass spectrometer.




118

Course Subject Technical Courses in Dental Sciences: Dental Pharmacology



Credits 2

Day/time of classes Monday / 4-5th Place Mol. Biol. & Biochem. Room in

Lab. of Pharmacol.


[Aims] This course is designed to help students master molecular biological, electrophysiological and pharmacological techniques which enable them to perform their thesis works by themselves. [Contents] We will lecture on the principles of the following techniques, and there-

after students will have practical training. 1) Mammalian cell culture 2) PCR analysis 3) Cloning method and sequence analysis 4) Gene transfection 5) Patch-clamp techniques 6) Measurement of changes in the intracellular Ca2+ concentration





119

Course Subject Technical Courses in Dental Sciences:Oral Microbiology



Credits 2

Day/time of classes Consult with learners Place Laboratories of Oral

Microbiology


Aims Students learn experimental techniques for microbiology, immunology and related fields. Contents 1. Students learn experimental techniques for microbiology,

immunology and related fields; such as cell culture, ELISA, RT-PCR, real-time PCR, Western blotting, flow cytometry, immunostaining, and experiments using animals (mainly mice).

2. Students could select techniques among the above program with consultation.

Text/Materials/References etc. Protocols and suitable materials are available.

Method of evaluating performance By attendance to training course.


120

Course Subject Technical Courses in Dental Sciences: Periodontology and Endodontology



Credits 2

Day/time of classes Consult with learners Place Practice room in Division of

Periodontology &Endodontology


Aims

Learning of required experimental skill in Periodontology, Endodontology and the related fields. Contents

Learning of required experimental skill to research Periodontology, Endodontology and the related fields on a one-on-one coaching. 1. Cell culture 2. ELISA 3. RT-PCR and Real-time PCR 4. Western blotting 5. Flowcytometry 6. Basic technique in animal experiment (mouse and rat)

Text/Materials/References etc. Provide materials if needed


Comments Number of students may be limited. Students should contact the following before registration. Assoc. Prof. NEMOTO [email protected]

121

Course Subject Technical Courses in Dental Sciences: Oral Molecular Bioregulation



Credits 2

Day/time of classes

Second semester/Mon. 4th and 5th periods Place Collaborative Experimental Lab.

Ⅵ (Building C)


Aims Master the basics of Western blotting, and utilized the skills in the research. Contents 1. Master the basic principles of Western blotting (Sugawara)

2. Learn the skills of Western blotting (Kuroishi)

3. Discuss the application of research (Sugawara and Kuroishi)




122

Course Subject Technical Courses in Dental Sciences: Oral and Craniofacial Anatomy



Credits 2

Day/time of classes

Second semester Consult with learners Place Consult with learners


Aims To learn methods about making histological sections Contents 1. Perfusion with fixative 2. Cutting sections 3. Immunohistochemistry 4. Taking microphotographs


Method of evaluating performance By presence


123

Course Subject Technical Courses in Dental Sciences: Dental and Digital Forensics



Credits 2

Day/time of classes



The aim:

The aim of this course is to acquire the techniques to identify human skeleton or teeth, and bone fragments as well.

Content of Class:

Identification of human bones Identification of human permanent teeth Identification of human deciduous teeth Identification of fragments of bones or teeth




Grading will be based on participation and practical skills test


124

Course Subject Technical Courses in Dental Sciences: Oral Physiology


○ Takashi TODA

Credits 2



The aim of this course:

1. To learn the in vivo experimental methods of neurophysiology using rats.

2. To understand the in vivo experiment methods for somatic sensation. 3. To understand the methodology of acute experiments of animals. Contents of Course: 1. Methodology of anesthesia of animals 2. Methodology of recordings neuroactivities with metal microelectrodes 3. Methodology of animal preparations 4. Methodology of vivo electrical stimulation to peripheral nerves 5. Methodology of vivo electrical stimulation to central nervous system 6. Methodology of data analysis 7. Methodology of tissue preparations




125

Course Subject Technical Courses in

Dental Sciences: Advanced Prosthetic

Dentistry Instructor

(○: responsible instructor)


Credits 2

Day/time of classes

The 1st term Tuesday, 4- 5st period Place The office of Advanced

Prosthetic Dentistry

Aims & Content of

Class

【Aim】 Learn the research-methods with technical procedure for performing own research experiment. 【Contents】 1. in vivo measurement

① using a strain gauge and pressure-transducer ② using a 3D load-measuring sensor installed in a dental crown

and implant. ③ using a pressure sensor sheet to measure the mechanical stress

beneath a denture-base (Instructor: Keiichi Sasaki)

2. Measurement of the bone metabolic activity using a bone scintigraphy

(Instructor: Toru Ogawa)

3. Measurement of the function with mastication and swallowing ① EMG (Electromyogram) of masticatory muscles ② Measurement of tongue movement

(Instructor: Toru Ogawa, Soshi Hanawa)

4. Prospective clinical study (Instructor: Toru Ogawa)


Method of evaluating performance Attendance and report of an assignment.

Comments


126

Course Subject Technical Courses in Dental Sciences: Aging and Geriatric Dentistry



Credits 2


Dentistry


The aim of this course:

To learn the research methods for capturing, analyzing, and evaluating various oral functions

Content of Class:

1. Registration, analysis and evaluation of the motion of the jaw 2. Registration, analysis and evaluation of the electromyography of the jaw muscles 3. Registration, analysis and evaluation of the chewing oral function 4. Registration, analysis and evaluation of the occlusion of the dentitions




127

Course Subject Technical Courses in Dental Sciences: Comprehensive Dentistry



Credits 2

Day/time of classes

Second Term Monday /4th & 5th Period Place Office of Comprehensive

Dentistry


The aim of this lecture: To learn the theoretical and practical methods for dental education especially related to the post clinical training program. Content of Class: 1. History of dental education 2. Theory of dental education 3. Objectives of dental education 4. Methods for dental education 5. Evaluation for dental education




128

Course Subject Technical Courses in Dental Sciences: Dental Biomaterials



Credits 2

Day/time of classes

Consecutive three days (all day) in the first or last semester



Aim The aim is to practice the research technique for observation methods and elemental analyses working for own research theme, using a scanning electron microscope (SEM) and an electron probe X-ray microanalyzer (EPMA), respectively.

Contents

Principle of a scanning electron microscope Preparation of specimens Observation methods

Principle of an electron probe X-ray microanalyzer Preparation of specimens Elemental analysis methods

Qualitative analysis Quantitatively analysis Mapping analysis



Comments

Learners must participate in the Practice Course (Dental Biomaterials). The lecture days will be adjusted after consultation with the learners. (Presence in all day is necessary on lecture days.) Students should contact the following before registration. Assoc. Prof.TAKADA [email protected]

129

Course Subject Technical Courses in Dental Sciences: Operative Dentistry


○Keisuke HANDA

Credits 2

Day/time of classes Consult with learners Place Laboratory of Division of

Operative Dentistry


The aim of this course Basic understanding of cell culture and animal model experiment to master technology of regeneration therapy. Contents of Class : 1. Learning of cell culture technology

Understanding of basic technology of osteoblast cell culture which is important for bone regeneration therapy.

2. Gene expression analysis

Understanding of the experimental technique for gene expression analysis including RNA isolation and PCR technology to investigate osteoblast differentiation.

3. Implantation analysis Understanding of implantation analysis using immunodeficiency animal to investigate bone regeneration ability in vivo



Comments

Day/time of this class flexible Students should contact the following before registration. Prof.SAITO [email protected]

130

Course Subject

Technical Courses in Dental Sciences: Molecular and Regenerative Prosthodontics


○ Hiroshi EGUSA Masahiro YAMADA

Credits 2

Day/time of classes Consult with learners Place

Laboratory of the Division of Molecular and Regenerative Prosthodontics


[Aim]

To learn the basic experimental skills for research of molecular and regenerative prosthodontics.

[Contents]

1. Lectures on stem cell culture 2. Stem cell culture 3. Guided differentiation of stem cells 4. Discussion and reports on the outcome of the experiments

Text/Materials/References etc. At the Bench: A Laboratory Navigator, Kathy Barker


Comments

Number of participants may be limited. Applicants should contact with Prof. Egusa before registration. Students should contact the following before registration. Prof.EGUSA [email protected]

131

Course Subject Technical Courses in Dental Sciences: Preventive Dentistry


○ Takeyoshi KOSEKI Naoko TANDA Ryouichi HOSOKAWA Hanako SUENAGA Masaki SUGAZAKI Credits 2

Day/time of classes


Dentistry

Aims & Objective of Class

Aims and objectives : To understand the basic methodology of preventive dentistry, we demonstrate the several experiment techniques and clinical procedures of public health and preventive dentistry. Content of class: (January 2014)

Monitoring method of climate and environment Monitoring method of air pollution Monitoring method of drinking water Body measurement and nutrition evaluation

(July 2013) Diagnostic method of early caries lesions Methods of oral hygiene Oral examination Application of fluoride for the prevention of dental caries Risk assessment of the dental caries Periodontal examination Scaling and root planing Professional mechanical tooth cleaning



Comments


132

Course Subject Technical Courses in Dental Sciences: Pediatric dentistry



Credits 2

Day/time of classes

Jun, Oct (Thu 4 and 5th period) Place suspense


[Purpose] Purpose of this course is learning the induction methods of ameloblasts and odontoblasts from precursor cells to develop the tooth regeneration. [[Contents] 1) Culture and evaluation of dental epithelial cells inducted by growth

factors. 2) Induction of neuronal, odontoblstic and adipogenic cells fron dental

pulp stem cells. 3) Culture of dental pulp cells from primary tooth. 4) Gene expression screening of tooth specific genes to evaluate the tooth

cell phenotype.



Comments


133

Course Subject Technical Courses in Dental Sciences: Orthodontics and Dentofacial Orthopedics



Credits 2

Day/time of classes

The time of classes will be decided in consulting with student.

Place Laboratory of Orthodontics and Dentfacial Orthopedics, and etc.


[Aims] The aim is to learn the methods of examination and analysis in orthodontic field and related fields, and to learn basic experimental technique to study basic research of biological reaction in orthodontic treatment. [Content of Class] Students learn the examination, analysis and experimental technique of basic knowledge in orthodontic field and related fields by one-to-one. The class contents are decided in consultation with students attending a lecture. Our plans are the following contents. In addition, the master's course and Ph.D. course are opened at the same time and aim at learning a basic technique and theory. 1. Cell culture (Periodontal cells, bone related cells etc.) 2. Animal experimentation (mouse, rat, dog etc.) 3. In situ hybridization 4. Immunohistology 5. Confocal laser scanning microscopy 6. Orthodontic materials 7. Cephalometric analysis 8. Three-dimensional analysis of stomatognathic function 9. Introduction of medical statistics 10. Application of medical statistics



Method of Evaluating Performance Based on attendances of classes and reports

Comments

Students who take this course are required to contact Teruko Takano-Yamamoto, to attend the classes. Students should contact the following before registration. Prof. YAMAMOTO [email protected]

134

Course Subject Technical Courses in Dental Sciences: Oral Dysfunction Science



Credits 2

Day/time of classes

The 2nd semester, Thursday, The 4th and 5th classes

Place Seminar & Training Room of Oral Dysfunction Science


The aim of this technical course:

To learn various examinations and analyses that are necessary for diagnosis, treatment planning, and treatment evaluation of dentofacial anomaly and jaw deformity.

Content of Class: 1. Various radiographic examinations (Instructors: Kaoru Igarashi and others) 2. Roentgenographic cephalometric analyses (Instructors: Kaoru Igarashi and others) 3. Examinations of various oral functions (Instructors: Kaoru Igarashi and others) 4. Other examinations and analyses (Instructors: Kaoru Igarashi and others)


Assigned textbooks on orthodontics and orthognathic surgery


Comments


135

Course Subject Technical Courses in Dental Sciences: International Oral Health



Credits 2

Day/time of classes

First Term Thursday /4and5th period

Place The seminar room of the department


The aims of this lecture are: To make a plan of international collaboration on oral health targeting

some developing countries. To learn the framework of global cooperation in health field.

Content of class: ・ To comprehend the indicators in global oral health situation and the

project cycle management. ・ To analyze the data on health of Japan and other OECD countries. ・ To make a proposal of international collaboration with a developing

country in South –East Asia.




136


Dental Sciences: Oral Pathology



Credits 2

Day/time of classes

First semester Fri 4,5 Place Division of Oral Pathology


[Objective] Preparation and histological observation of tissue specimens are learned. If indicated, specific staining, immunohistochemistry, and molecular investigation are added. [Contents] Preparation of tissue specimens, containing fixation, embedding, sectioning, and staining, are exercised. Significance of the histopathological features and other examination is discussed.




137


Dental Sciences: Oral Diagnosis



Credits 2

Day/time of classes

Mondays～Fridays 1,2 hours Place

Mainly at Tohoku University Hospital Oral Diagnosis outpatient ambulatory


【AIM】 Learn the method of oral diagnosis based on knowledge from scientific evidence and logical thinking. 【CONTENTS】・Learn examination of X-ray CT imaging in practice (Requires diagnostic imaging knowledge) ・Learn diagnosis of Orofacial Pain in practice (Requires physiological knowledge) ・Learn diagnosis of Taste Disorder in practice (Requires physiological knowledge) ・Learn diagnosis of Dry mouth in practice (Requires physiological knowledge) ・Learn diagnosis of Oral Mucosa Disease in practice (Requires immunological knowledge)



Method of Evaluating Performance Attendance, behavior, and reports

Comments

Wear fresh white coat in clinical exercise. Day/time of classes is subject to change by consulting with the students. Students should contact the following before registration. Prof. Takashi SASANO [email protected]

138

Course Subject Technical Courses in Dental Sciences: Oral and Maxillofacial Surgery


○ Tetsu TAKAHASHI Shiro MORI Wataru HASHIMOTO

Credits 2

Day/time of classes

Friday, 4th and 5th hour Second semester Place



【Aims】 To master practical technique for the experiments for development of oral and maxillofacial surgery after planning of the research projects 【Contents】 1. Statistical analysis for clinical study of oral and maxillofacial

surgery 2. Methods for researches on control of tumors on oral and maxillofacial

region 3. To learn how to make a frozen section, how to make a pathological

tissue section, a various kind of staining method 4. Research method for clinical application of regenerative medicine in

oral and maxillofacial region 5. Clinical observation and methods of analysis of interface between

bone and dental implants 6. Methods of histomorphometric analysis on oral and maxillofacial

regeion 7. New methods of morphometric analysis using diagnostic imaging

such as computed tomography




Comments


139

Course Subject Technical Courses in Dental Sciences: Dento-oral Anesthesiology



Credits 2

Day/time of classes

The second semester Friday, the 4・5th

period Place



【Aim】 To learn how to make the study design and carry out the research in dento-oral anesthesiology. 【Contents】 1. Basic research of anesthesiology i) Study Design ii) Methodology iii) Evaluation of study 2. Clinical reserach of anesthesiology i) Study Design ii) Methodology iii) Evaluation of study 3. Medical statistics 4. Presentation



Comments


140

Course Subject

Technical Courses in Dental Sciences: Craniofacial Development and Regeneration



Credits 2


Development and Regeneration


Aim of this course: To learn methodology that is used for research in tissue biology. Content of the class: To learn and/or experience the following methodologies 1. Animal experiments 2. In situ hybridization 3. Immunonhistochemistry 4. Electron microscopy 5. Micro–computed tomography (Micro-CT)



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.Yasuyuki SASANO [email protected]

141

Course Subject Technical Courses in Dental Sciences: Craniofacial Function Engineering



Credits 2




The aims of this lecture: To understand the methodology of tissue engineering and the materials used such as synthetic biomaterials and stem cells. Content of class: 1. Methodology of tissue engineering 2. Analyses of scaffold materials, such as biodegradable polymers and inorganic hydroxyapatite (HA) and octacalcium phosphate (OCP), by x-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy 3. Cells culture



Comments


142

Course Subject Technical Courses in Dental Sciences: Division of Community Oral Health Science



Credits 2

Day/time of classes

the 1st term, Tuesday, 4th -5th periods Place Laboratory of Community Oral

Health Science


The aim:

To learn about the outlines of clinical epidemiologic studies in the dentistry.

Content of Class:

1. Research design of clinical epidemiology 2. An introduction to genome cohort study 3. Medical statistics 4. Presentation for medical research



Comments


143

Course Subject Technical Courses in Dental Sciences: Oral Cancer Therapeutics


○ Hisanori HORIUCHI Ryutaro SHIRAKAWA

Credits 2

Day/time of classes

Consult with Hisanori Horiuchi Place

Department of Molecular and Cellular Biology, Institute of Development, Aging and Cancer


The aim: To learn the experimental technique of molecular biology for the analysis of intracellular signal transduction Content of Class: Training course of experimental technique of molecular biology including generation and purification of recombinant proteins and biochemical experiments and producing antibodies with them



Comments

Day/time of this class is flexible. Students should contact the following before registration. Prof.HORIUCHI [email protected]

144

Course Subject Technical Courses in Dental Sciences: Molecular Oral Oncology



Credits 2

Day/time of classes




The aim: To learn the experimental technique of molecular cell biology for the analysis of transcription factors and nuclear proteins Content of Class: Training course of experimental technique of molecular cell biology including cell culture, protein analysis, gene expression analysis and epigenetic analysis



Comments


145

Course Subject Technical Courses in Den-tal Sciences: Bio-Dental Engineering


○ Shinji KAMAKURA

Credits 2

Day/time of classes

The second semester Monday 13:00~16:10 Place Laboratory of Bone Regenerative



Aims

To learn fundamental technical skills concerning about Bio-Dental Engineering

and related field in the course of implantation of biomaterials to the tissues in

experimental animals, such as rats and so on.

Contents

1. Implantation procedures of biomaterials in experimental animals

2. Procedures of perfusion fixation

3. Preparation of histopathological specimens of hard tissues

4. Staining technique of histopathological specimens of hard tissues

5. Histomorphometry of histopathological specimens of hard tissues



The evaluation is performed based on the attendance at the class and scores on the submitted reports.

Comments

Opening hours and place of the class will be altered in accordance with consulting with participants. An applicant should attend the education and training by Institute for Animal Experimentation Tohoku University School of Medicine in advance. Because of restriction on number of accepted applicants, an applicant should consult with main instructor beforehand. Students should contact the following before registration. Prof. KAMAKURA [email protected]

146

Course Subject Technical Courses in Dental Sciences: Intractable Diseases and Immunobiology



Credits 2



[Aim] To acquire the methods for immunology and molecular biology. [Contents] 1. Cellular Immunology methods. 2. Molecular biology and immunology methods.

3. Advanced scientific methods.

Our lab member only. If you take the class, you should belong to our lab.



Comments


147


Dental Sciences: Oral cancer screening


○ Hiroyuki Kumamoto Takashi Sasano Tetsu Takahashi

Takeyoshi Koseki Credits 1

Day/time of classes Not determined Place Not determined


[Objective] Oral cancer accounts for about 2% of total malignancies and recently increases. Since outcome of oral cancer depends on stages of the lesions, it is important to find the early lesion of oral cancer. Purpose of this course is to detect early oral cancer and to work together with high-order hospitals. [Contents] ・Pathology of oral cancer and precancerous lesions. ・Diagnosis of oral mucosal lesions. ・Clinical aspects and therapies of oral cancer. ・Oral care for patients with cancer.



Comments This program is one of intensive courses in professional training plan for cancer in Tohoku, and is held in open-class system for dentists.

148

9. School/Graduate School of Dentistry Student Counseling Center

The Tohoku University School/Graduate School of Dentistry provides a Student Counseling Center for dealing with problems experienced by graduate and undergraduate students. The center provides counseling for a variety of issues, from concerns related to studies, career and lifestyle, to coercion by religious groups and sexual harassment. If necessary, the center will provide information on appropriate services and specialists. Students with concerns are encouraged to request counseling at an early stage.

The details of counseling are kept strictly confidential, but if a student’s issue cannot be resolved by the Counseling Center alone, concerned instructors or staff may be consulted, with permission from that student. Counseling Hours: As needed, subject to availability of instructors and counselors. Contact: Student’s Affairs

(TEL 717-8248; E-mail: [email protected]) Counselors: [Undergraduate Students] Undergraduate Educational Records and Programs

Committee Director, Educational Records and Programs Committee in charge of each grade [Graduate school Students] Graduate Educational Records and Programs Committee Director

149

course curriculum · 1. compulsory courses (1) the student must take introduction to dentistry,...

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