coronary artery surgery results in 2016

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The Survey Committee of Japanese Association for Coronary Artery Surgery (JACAS) Coronary artery surgery results In 2016

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The Survey Committee of Japanese Association for Coronary Artery Surgery (JACAS)

Coronary artery surgery results

In 2016

Coronary artery bypass grafting (CABG), 2016 Total cases : 12,729 Isolated CABG : 8,492 (67%)(previous year:70%)

Concomitant CABG : 4,237 (33%)(previous year:30%) Isolated CABG Initial elective : 7,142 Except initial elective :1,350

Off-pump : 4,424 Off-pump : 695 On-pump : 2,718 On-pump : 655 (Off-pump rate : 62%) (Off-pump rate : 51%) (previous year : 63%) (previous year : 51%)

Changes of off-pump CABG rate(Initial elective CABG)

62%

0

10

20

30

40

50

60

70

80

1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

%

year

Initial elective CABG :7,142(100%) On-pump (arrest) :1,706(23.9%) On-pump (beating) :1,012(14.2%) Off-pump (total) :4,424(61.9%) Off-pump (complete) :4,322 On-pump (conversion) : 102 Off-pump complete rate :97.7%

Off to on-pump conversion rate :2.3% (previous year:1.8%)

Mortality of isolated CABG :1.66% (previous year:1.72%) Mortality of initial elective CABG:1.09% (previous year:0.83%) On-pump (arrest) :1.29% On-pump (beating) :1.28% Off-pump (total) :0.97% Off-pump (complete):0.86% (previous year:0.54%) On-pump (conversion):5.88% (previous year:4.40%)

Changes of mortality (Isolated and initial elective CABG)

1.66%

1.09%

0

0.5

1

1.5

2

2.5

3

3.5

4

1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

mo

rtal

ity

(%)

year

Isolated CABG

Initial elective CABG

Changes of mortality for procedures(Initial elective CABG)

0

1

2

3

4

5

6

7

8

2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

mo

rtal

ity

(%)

year

Off-pump(complete)

On-pump(beating)

On-pump(arrest)

Off to on-pump(conversion)

Mortality according to number of diseased vessels (Initial elective CABG:7,142, mortality:1.09%)

mortality

(%)

1.0

0 25 50 75 100 (%)

1VD

(0%)

2VD

(0.65%)

3VD

(1.20%)

LMT

(0%)

LMT+2VD

(0.78%)

LMT+1VD

(0.62%)

LMT+3VD

(1.56%)

2.0

Mortality according to number of diseased vessels (Except initial elective CABG:1,350, mortality:4.67%)

mortality

(%)

10

5

0 25 50 75 100 (%)

1VD

(7.50%)

2VD

(4.49%) 3VD

(4.17%)

LMT

(5.00%)

LMT+1VD

(0.00%)

LMT+2VD

(5.20%)

LMT+3VD

(5.08%)

mortality

(%)

10

5

0 25 50 75 100 (%)

Off-pump (total)

2.59%

On-pump

(beating)

7.46% On-pump

(arrest)

6.14%

Mortality according to surgical procedures (Except initial elective CABG:1.350, mortality:4.67%)

Graft number according to procedures(Initial elective CABG)

Total

On-pump

(arrest)

On-pump

(beating)

Off to on

(conversion)

Off-pump (complete)

0 25 50 75 100%

average No. (previous year)

3.05

(2.99)

3.17

(3.17)

3.10

(3.01)

3.25

(3.08)

2.99

(2.74)

1 2 3 4≦

4≦

4≦

4≦

4≦

2 1

graft number

4≦

0 25 50 75 100%

Off-pump

Off to on-pump (conversion) On-pump (beating)

On-pump

(arrest)

Off-pump

Off-pump

Off-pump

On-pump

(arrest)

On-pump

(arrest)

On-pump

(arrest)

57.2%

Procedure according to graft number(Initial elective CABG)

graft number

On-pump (arrest) vs. off-pump (Initial elective CABG)

0 25 50 75 100%

On-pump (arrest)

On-pump (arrest)

On-pump (arrest)

Off-pump

Off-pump

Off-pump

68%

68%

88%

91%

78%

76%

bypass+

bypass −

RCA

LAD

LCX

Off-pump vs. off to on-pump conversion (Initial elective CABG)

0 25 50 75 100%

RCA(+) 3,003

LAD(+) 4,497

LCX(+) 3,367

RCA(−) 1,421

LAD(−) 93

LCX(−) 1,057

Off-pump

Off to on-pump conversion

2.3%

2.0%

2.5%

2.1%

10.7%

1.6%

Off-pump

Off-pump

Off-pump

Off-pump

Off-pump

Bypass No. conversion

rate

Age distribution according to gender (Initial elective CABG)

2000 1000 1000 0 0

313

780

2094

2212

709

60

123

420

677

330

49≧

60−69

50−59

70−79

≧80

(Age) Male:79.1% Female:20.9%

3000

(case) (case)

Changes of elderly cases(Initial elective CABG)

50.9%

13.5%

0

10

20

30

40

50

60

2000 2001 2002 2003 2004 2005 2006 2008 2009 2010 2011 2012 2013 2014 2015 2016

%

year

70 y.o. ≦

80 y.o. ≦

Changes of mortality according age(Initial elective CABG)

0

0.5

1

1.5

2

2.5

3

3.5

2000 2001 2002 2003 2004 2005 2006 2008 2009 2010 2011 2012 2013 2014 2015 2016

mo

rtal

ity

(%)

year

49 y.o. ≧

50-59 y.o.

60-69 y.o.

70-79 y.o.

80 y.o. ≦

Graft selection (Total graft number of isolated CABG:22,938)

GEA

(3.2%)

RA

(3.8%)

LITA

(35.3%)

RITA

(15.6%)

SVG

(42.1%)

Changes of graft selection

0

5

10

15

20

25

30

35

40

45

2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

%

year

LITA

RITA

GEA

RA

SVG

0

0.5

1

1.5

2

2.5

3

3.5

4

4.5

Off-pump (complete) On-pump(arrest) On-pump(beating) Off to on-pump (coversion)

%

Stroke rate according to procedures(Isolated CABG)

Stroke cases:108

Stroke rate:108/8492(isolated CABG)=1.27%

1.10% 1.05%

1.96%

3.96%

p:0.0072

p:0.0332

p:0.0071

Results of emergency CABG after PCI complications

Emergency CABG; operation after PCI complications (coronary

occlusion and/or bleeding), within 24 hours

Cases:78

Rate:78/8492(isolated CABG);0.92%

Death cases:8

Mortality:10.2%

Results

cases death cases mortality(%)

CABG① 21 1 4.76

CABG② 27 3 11.11

CABG③ 16 3 18.75

CABG④ 6 0 0

Other procedures 8 1 12.5

Changes in results of ventricular septal perforation

Total No.:174, death:37 (mortality:21.2%)

0

10

20

30

40

50

60

mo

rtal

ity

(%)

year

Results of ventricular septal perforation (1)

alive

0 50 100 150

Total cases

Bypass(+)

Bypass(−)

death

37

174(mortality;21.2%)

72 13

102 24

137

78

(mortality;18.0%)

(mortality;23.5%)

(case)

200

59

Results of ventricular septal perforation (2)

0 50 100 150

Patch closure

alive

death

(mortality;22.0%)

18

19

(mortality;22.2%)

(mortality;21.0%)

(case)

Infarction exclusion

50

76

39 11

93 (mortality;18.4%)

Anterior infarction(mortality;19.5%)

Post-inferior infarction(mortality;26.8%)

52 14

Others 7 (mortality;14.2%)

14

15

Others 4 (mortality;75%)

4

1 3

6 1

Patch closure

Infarction exclusion

4

0

10

20

30

40

50

60

70

2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

mo

rtal

ity

(%)

Anterior VSP

Post-inferior VSP

Changes in results of ventricular septal perforation

according to region

year

Changes in results of papillary muscle rupture

Total No.:32, death:4 (mortality:12.5%)

0

5

10

15

20

25

30

35

40

45

50

mo

rtal

ity

(%)

year

0 10 20 30

Total cases

Bypass(+)

Bypass(−)

alive

death

32 (mortality:12.5%)

12

20 17

(mortality;8.33%)

(mortality;15.0%)

(case)

4 28

11

3

1

Results of papillary muscle rupture

Total No.:144, death:38 (mortality:26.4%)

0

20

40

60

80

100

120

mo

rtal

ity

(%)

year

Changes in results of LV free wall rupture

0 50 100 150

Total cases

Bypass(+)

Bypass(−)

alive

death

144 (mortality;26.4%)

(mortality;54.2%)

(mortality;9.5%)

(case)

38 106

Blowout type 60 (mortality;50.0%) 30 30

12 (mortality;33.3%) 8

48 26 22

Oozing type

Bypass(+)

Bypass(−)

84 8 76

22 (mortality;9.1%)

6 56 62 (mortality;9.7%)

20

4

2

Results of LV free wall rupture

0

10

20

30

40

50

60

70

80

2009 2010 2011 2012 2013 2014 2015 2016

mo

rtal

ity

(%)

Blowout type

Oozing type

Changes in results of LV free wall rupture

according to rupture type

year

Changes in results of left ventricular aneurysm (LVA)

Total No.:164, death:8 (mortality:4.87%)

0

2

4

6

8

10

12

14

16

18

mo

rtal

ity

(%)

year

0 100 200 300

Total cases

Bypass(+)

Bypass(−)

alive

death

8 (mortality;4.87%)

114

156

109 (mortality;4.38%)

(mortality;5.88%)

(case)

51 48

164

Results of left ventriculoplasty and/or aneurysmectomy

5

3

0 100 200

Total cases

death

312 (mortality;3.84%)

(case)

12 300

Total

Bypass(+)

Bypass(+)

Bypass(−)

Bypass(−)

Total

226(mortality;1.76%) 4 222

200(mortality;2.00%) 271

26(mortality;0%)

26

86(mortlity;9.30%)

78

59(mortality;11.86%)

8

52

27(mortality;3.70%)

26

alive

Mitral valve

plasty

Mitral valve

replacement

50 150 250

7

300

196 4

1

Results of MVR or MVP for ischemic MR

0 50 100 150

Total cases

death

67 (mortality;5.97%)

(case)

4

Total

Bypass(+)

Bypass(+)

Bypass(−)

Bypass(−)

Total

55(mortality;5.45%) 52

38(mortality;7.89%) 35

17(mortality;0%)

8(mortality;0%)

8

12(mortality;8.33%)

4(mortality;25.0%)

alive

Left ventriculoptasty

+ Mitral valve plasty

17

11

63

3

1

3

3

1

Results of ischemic MR+LVA or ischemic cardiomyopathy

Left ventriculoptasty

+ Mitral valve

replacement

Conclusions (1)

1. The mortality of isolated CABG was 1.66%, that of initial

elective CABG was 1.09%, indicating almost same excellent

results than those of previous year.

2. Of initial elective CABGs, 62% cases underwent off-pump

procedure, showing still high rate. The mortality of off-pump

was 0.86%, which was slightly higher than that of previous

year, indicating still good results.

3. Off to on-pump conversion rate was 2.3%, and the mortality

of those cases was 5.88%, resulting getting worse.

4. The more bypass number, the lower the off-pump rate.

However, of all 4 and/more bypass procedures, 57.2% cases

were done by off-pump CABG.

5. CABG cases is getting older year by year, more than 70

years old patients rate was 50.9%, more than 80 was 13.5%,

showing high rate.

Conclusions (2)

6. Arterial grafts were used in 57.9%n of all grafts, while vein

grafts were used in 42.1%. The frequency of vein graft

usage increased in recent years.

7. The complication rate of central nerve system stroke of all

isolated CABG was 1.27%. This rate of off-pump CABG

showed significantly lower than those of on-pump (beating)

and off to on-pump conversion procedures, resulting

OPCAG can avoid this complication.

8. After PCI complications, emergency operation underwent in

0.92% of all isolated CABG within 24 hours. The mortality of

those cases was 10.2%, showing still high rate.

9. The results of complications for acute and old myocardial

infarction improved than those of previous year. However,

the mortality of post-inferior VSP and blowout type free wall

rupture, were high rate, indicating worse prognosis.

Special survey of intra-operative graft flow measurement for CABG

The Survey Committee of Japanese Association for Coronary Artery Surgery (JACAS)

Question 1 ;Do you know that an intra-operative graft flow measurement fee can

charge as payment for medical services ?

Question 2 ;Do you charge this fee, actually ?

Yes(90.2%)

No(9.8%)

Yes(78.6%)

No(21.4%)

Question 3 ;What kind of equipment do you use for intra-operative graft flow

measurement ?

0

50

100

150

200

250

TTFM TTFM+Echo Echo others

215

26

6 6

Question 4 ;What kind of parameters do you measure for intra-operative graft

flow measurement ?

0

50

100

150

200

250

mean flow PI DF flow waveform

others

236

196

108

202

3

Question 5 ;What kind of parameters do you emphasize for intra-operative

graft flow measurement ?

0

20

40

60

80

100

120

140

160

180

200

mean flow PI DF flow waveform

others

174

140

10

81

3

Question 6 :Do you use any diagnostic image equipment except graft flow

measurement ?

Yes(16.5%)

No(83.5%)

Question 7 :What kind of diagnostic image equipment do you use ?

0

5

10

15

20

25

30

SPY PDE Echo Others

11

26

10

6

Question 8 :How many grafts did you revise to perform CABG due to

abnormal graft flow measurement, in last year ?

Answer; 347

Question 9 :How many grafts did you perform CABG, in last year ?

Answer; 29,008

Revision rate;1.2%

Question 10 :What were the reasons for revision to perform CABG ?

0

20

40

60

80

100

120

Technical error Graft dissection Coronary arterydissection

Bleeding and/orhematoma

Unknouw Others

108

36

14 13

23 15

Question 11(1) :Do you have any standard to revise to perform CABG ?

83

33

23

14

7

0

10

20

30

40

50

60

70

80

90

Graft flow measuement(flow, PI, DF)

Flow wave form Anastomosis shape Diagnostic imaging Doppler flow meter

Question 11(2) :Do you have any standard to revise to perform to CABG ?

(detail of graft flow measurement standard)

0

1

2

3

4

5

6

7

8

9

10

0 < 10 <15 < 20

0

2

4

6

8

10

12

> 4 > 5 > 10

mean flow PI

DF < 60% : 2

(ml/min)

Question 12 :Do you think that an intra-operative flow measurement is useful

to prevent graft failure for CABG?

No(3.6%)

Yes(96.4%)