Through its strategic CORES program (Centralized Operations of Research Equipment and Supports), the Faculty of Medicine has developed a range of multi-user research facilities providing access to sophisticated equipment and services supported by trained experts.

The CORES facilities welcome users from the Dalhousie community, other academic institutions, and external commercial groups.

CORESRESEARCH FACILITIES

FACULTY OF MEDICINE

ADVANCE YOUR RESEARCH WITH STATE-OF-THE-ART FACILITIES AND SERVICES

FACULTY OF MEDICINE

CORES CONTACT:Jessica ConnorsManager, Research and Infrastructure Supportjessica.connors@dal.ca

dal.ca/medicine

The Flow Cytometry Core Facility maintains and operates several state-of-the-art flow cytometers that support a broad range of capabilities including:

FLOW CYTOMETRY

• Complex multi-colour analytical flow cytometry

• Full-service cell sorting

• Image cytometry (ImageStream®)

We offer comprehensive cytometry training for independent use of several instruments as well as expert consultation to optimize panel design and sample preparation.

For more information, please contact: Derek Rowter, Manager | cellsort@dal.ca | 902-494-7858

ELECTRON MICROSCOPY (EM)

The EM Core Facility provides advanced research services for both Transmission and Scanning EM applications, including:

• Sample preparation • Sample thick/thin

Critical point drying and sputter coating

• Use of JEOL JEM 1230 TEM and/or Zeiss Sigma 300 FESEM

We offer consultation and training for instrument operation and accessible EM-related techniques.

For more information, please contact: Mary Ann Trevors, Manager | mary.ann.trevors@dal.ca | 902-494-2346

• Sample preparation • Sample thick/thin

sectioning and staining

• Critical point drying and sputter coating

• Use of JEOL JEM 1230 TEM and/or Zeiss Sigma 300 FESEM

CELLULAR & MOLECULAR DIGITAL IMAGING (CMDI)

The CMDI Core Facility houses an array of sophisticated, state-of-the-art imaging systems that support a range of techniques including:

• Widefield fluorescent microscopy

• Confocal laser scanning microscopy

• Super-resolution microscopy

• Laser microdissection• Small animal CT scanning

We provide training for independent use of imaging systems as well as several workstations with software for image processing and 3D image reconstruction.

For more information, please contact: Stephen Whitefield, Manager | s.whitefield@dal.ca | 902-489-7849

• Widefield fluorescent microscopy

• Confocal laser scanning microscopy

• Super-resolution microscopy

• Laser microdissection• Small animal CT scanning

The BMS Core Facility offers a full range of mass spectrometry-based analytical services including:

• Proteomics• Metabolomics

• Lipidomics• Customized MS methods

These workflows can be tailored to meet specific needs through one-on-one support from technical experts.

For more information, please contact: Alejandro Cohen, Manager | alejandro.cohen@dal.ca | 902-494-8359

BIOLOGICAL MASS SPECTROMETRY (BMS)

• Proteomics• Metabolomics

• Lipidomics• Customized MS methods

FACULTY OF MEDICINE

CORES CONTACT:Jessica ConnorsManager, Research and Infrastructure Supportjessica.connors@dal.ca

dal.ca/medicine

ZEBRAFISH

The Zebrafish Core Facility provides researchers with state-of-the-art zebrafish resources and services including:

• Microinjection suite• Fluorescent microscopy suite• Behavioral monitoring lab•

• • Breeding and maintenance• Embryo procurement on request

All animal husbandry and system monitoring is conducted by trained staff so you can focus on your research!

For more information or to request tissues, please contact: David Malloy, Manager | zebrafishcore@dal.ca | 902-494-2031

• Breeding and maintenance• Embryo procurement

on request

• Microinjection suite• Fluorescent

microscopy suite• Behavioral monitoring lab

MARITIME BRAIN TISSUE BANK (MBTB)

The Maritime Brain Tissue Bank (MBTB) is a vital resource for researchers studying neurodegenerative diseases. Established in 1993, the MBTB contains brain tissues from healthy individuals and those affected by diseases, including:

• Alzheimer’s disease• Frontotemporal dementia• Lewy body disease

• Amyotrophic Lateral Sclerosis

• Multiple sclerosis

For more information or to request tissues, please contact: Andrew Reid, Manager | andrew.reid@dal.ca | 902-494-4130

• Alzheimer’s disease• Frontotemporal dementia• Lewy body disease

• Amyotrophic lateral sclerosis (ALS)• Multiple sclerosis• Parkinson’s disease

GENOMICS

The Genomics Core Facility provides access to next-generation sequencing (NGS) technologies and sample library preparation services for a range of applications including:

• Whole genome sequencing• Exome sequencing• Transcriptome sequencing

• Sanger Sequencing

We also offer sample DNA extraction and storage services.

For more information, please contact: Mathew Nightingale, Manager | genomics@dal.ca | 902-494-1203

• Whole genome sequencing

• Exome sequencing

• Transcriptome sequencing• Sanger sequencing