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CONNS

SYNDROMEBehrens, Aleah NestineLagman, Bunny Dawn

Perez, Patria Nia

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Hyperaldosteronism (2

types:!" Primary Hyperaldosteronism #$aused

%y an a%normality o& the adrenal $orte'

2" Secondary Hyperaldosteronism #results&rom sustained eleated renin release anda$tiation o& angiotensin ))

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*+NN- -.ND/+01A""a Primary Hyperaldosteronism

)s an autonomous se$retion o& e'$ess

aldosterone1stimated to %e !3 4 23 o& all hypertensie

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PA5H+PH.-)+L+6.:(most $ommon $ause is due to %enign

adrenal adenoma o& the zona glomerulosa orto hyperplasia o& the adrenal $orte'

)s due to e'$essie stimulation o& the normaladrenal $orte' %y angiotensin )), A*5H, oreleated potassium

*an also %e due to %ilateral adrenal nodularhyperplasia and adrenal $ar$inomas

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Hyperaldosteronism promotes:

)n$reased renal sodium and waterrea%sorption with $orresponding hyperolemi$and hypertension

/enal e'$retion o& potassium

*HA/A*51/)71D B.:

1'tra$ellular 8uid olume oerload

Hypertension -uppression o& normal &eed%a$ me$hanisms

o& renin se$retion

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-ymptoms:5he e'$hange o& ions normally &a$ilitated %y

aldosterone results in :

hypertension and potassium depletion0us$ular weaness*ardia$ arrhythmiasHypoalemia0eta%oli$ alalosis5etany and paresthesiaHypernatremia1'$essie loss o& waterLe&t entri$ular dilation

Hypertrophy

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D)A6N+-)-:5wo $riteria:

Plasma aldosterone must %e raised

while renin is low

0/), *5 and N0/ (Nu$lear 0agneti$/esonan$e # used to lo$ate the aldosterone4

se$reting adenoma

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19ALA5)+N :

Blood pressure: eleated

-erum and rinary ele$trolyte leels:

-erum Na; normal or-erum

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5/1A501N5 :

0anagement o& hypertension andhypoalemia

)& adenoma is present4 surgi$al remoal