As my colleagues already presented,spinal cord repair after follicle stem cell implantation because most of the transplanted cells differentiated into Schwann cells that apparently promote axonal growth and functional recovery. Firstly,two months after transplantation, GFP-expressing cells had migrated into the joined region of the previously severedthoracic region of the spinal cord, differentiated to Schwanncells and the mice recovered significant hind-limb function. Moreover,we showed that hair follicle stem cells can can readily generate neurons, glial cells and other cell types provide a potential solution to spinal cord injury and ,most important,they do not form tumors. Nestin-expressing stem cells from hair follicles differentiated into immature Schwann cells that accelerate axonal growth and function recovery . Secondly,the hair follicle stem cells, a defined population, can functionally repair the severed spinal cord.Cell-replacement therapies show particular promise in the nervous system, where transplanted embryonic or bone marrow stem cells have been shown to improve the regain of function in animal models of spinal cord or peripheral nerve lesion.In conlusion,these results suggest that hair follicle stem cells can promote the recovery of spinal cord injury. Thus, hair follicle stem cells provide an effective and accessible source of stem cells for the promising treatmentof peripheral nerve and spinal cord lesion.

Conclusion Spinal cord repair after follicle stem cell implantation. Nestin-expressing stem cells from hair follicles differentiated into immature Schwann cells that promote axonal growth and recovery of function after spinal cord injury. Nestin-expressing hair follicle stem cells are available from normal skin and they do not form tumors. These can readily generate neurons, glial cells and other cell types provide a potential solution to these problems. Hair follicle stem cells provide an effectiveaccessible source of stem cells for the promising treatment of peripheral nerve and spinal cord injury.