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TRANSCRIPT
COMMON EQUINE DISEASES – CAN dac® HELP? 2
OUTLINE
• Digestive Function • Diseases
– Equine Metabolic Syndrome – Cushings – Colic – Tying Up – COPD – HYPP – EPM – Ulcers – Kidney Disease – Liver Disease
• Questions
COMMON EQUINE DISEASES – CAN dac® HELP? 3
DIGESTIVE FUNCTION - EVOLUTION MODERN DIET • Cereal grain based • Rapid intake • Increased Acidity of GI Tract • Frustration due to confinement • Lack of Socialization • Exercise Level
NATURAL DIET • Fibre Based • Wide variety of forages • Nibbler – small amounts • Continuous Grazing • Moving while eating • Herd
COMMON EQUINE DISEASES – CAN dac® HELP? 4
DIGESTIVE FUNCTION – NUTRITIONAL DISORDERS
Change in horse’s diet & eating habits
– Fit human schedule
– Convenience
– Availability of feedstuffs
The key to understanding how to
feed horses is… the knowledge of
the digestive system and how it
functions.
COMMON EQUINE DISEASES – CAN dac® HELP? 5
DIGESTIVE FUNCTION - STOMACH
• One small compartment
• 9% of capacity
• Dictates meal size
• Acid, pepsin
• Protein digestion
COMMON EQUINE DISEASES – CAN dac® HELP? 6
DIGESTIVE FUNCTION – SMALL INTESTINE
• Seventy feet long • 25% capacity • Enzymatic digestion
– CHO
– Protein
– Fat
– Minerals
– Vitamins
COMMON EQUINE DISEASES – CAN dac® HELP? 7
DIGESTIVE FUNCTION – LARGE INTESTINE
• 65% of capacity
• Cecum and colon
• Enlargement to promote fermentation
• Microbial fermentation of plant fiber
– Volatile Fatty Acids
– B vitamins
• Absorption in Large Intestine
– Water
– Electrolytes
COMMON EQUINE DISEASES – CAN dac® HELP? 8
EQUINE DISEASES
General Symptoms of concern –
• Abnormal discharges from the eyes, nose or other body opening
• Foul breath • Limping • Loss of appetite or condition • Violent head shaking or scratching, licking or
biting any part of the body • Roughened coat or hair loss • Lumps or open sores
“All Disease Begins in the Gut” Hippocrates, Father of Medicine
COMMON EQUINE DISEASES – CAN dac® HELP? 9
EQUINE METABOLIC SYNDROME
• Obesity
• Insulin Resistance
• Laminitis
• Cushings
COMMON EQUINE DISEASES – CAN dac® HELP? 10
EQUINE METABOLIC SYNDROME
VMRCVM Study (Thatcher, 2007)
• 51% of ALL horses are overweight
• 19% Obese Scottish Study (Wyse et al., 2008)
• 32% of pleasure horses obese • 35% of pleasure horses fat
UK Study (Harker et al., 2011)
• 62% of horses competing at shows were overweight, fat or obese
COMMON EQUINE DISEASES – CAN dac® HELP? 11
EQUINE METABOLIC SYNDROME
• Obesity • Insulin resistance • Chronic inflammation • Oxidative stress • Impaired reproduction • Placental restriction • Lowered birth weights • Hyperlipemia • Laminitis • Heat Stress • Bone Injury • Joint Injury • Tendon Injury • Reduced Performance
COMMON EQUINE DISEASES – CAN dac® HELP? 12
EQUINE METABOLIC SYNDROME
• Grazing management
• Decrease Sugar and Starch
– Total diet less than 10 - 12%
• Antioxidants to support immune function
• Calories from fat not grain if weight gain needed
COMMON EQUINE DISEASES – CAN dac® HELP? 13
EQUINE METABOLIC SYNDROME
• dac® Oil
– Calories from fat
• dac® E & Se
– Antioxidants, immune function
• dac® DDA
– Immune function
COMMON EQUINE DISEASES – CAN dac® HELP? 14
TYING UP
• Azoturia, Exertional Rhabdomolysis, RER, PSSM, EPSM
• Muscle Damage, Pain
• Sporadic vs Chronic
• Sporadic occurs when horses are exercised in excess of their level of conditioning • Hot, humid conditions , increased
body temp
• Loss of fluid and electrolytes in sweat
• Depletion of muscle energy stores
COMMON EQUINE DISEASES – CAN dac® HELP? 15
TYING UP Chronic tying up
– repeated episodes
– increased muscle enzyme activity, even with mild exertion
– Abnormality in intracellular calcium regulation
– Abnormal muscle glycogen storage
– Genetic Component
COMMON EQUINE DISEASES – CAN dac® HELP? 16
TYING UP • Quarter horses, racing horses, draught
breeds
• Remove high starch and sugar ingredients – Corn, barley, molasses
• Increase fiber content & quality – Beet pulp, alfalfa
• Increase calories from fat
• Electrolyte supplementation
• Vitamin E supplementation
• Free Choice Salt
COMMON EQUINE DISEASES – CAN dac® HELP? 17
TYING UP
• dac® Oil
– Calories from fat
• dac® E & Se
– Muscle damage
• dac® Formula Calm B
– Reduce excitable behavior
• dac® Electro Aid
– Replace lost salts
COMMON EQUINE DISEASES – CAN dac® HELP? 18
COPD
• Chronic Obstructive Pulmonary Disease – Heaves
• Lung disease, similar to asthma
• Allergic reaction to inhaled particulates
• Air passages become inflamed
• Chronic cough or heaving to expel air and particulates
COMMON EQUINE DISEASES – CAN dac® HELP? 19
COPD
• Trouble breathing
• Cough
• Visible heave line of flank
• Wheezing
• Nasal discharge
• Inability to exercise
• Rapid breathing
COMMON EQUINE DISEASES – CAN dac® HELP? 20
COPD
• Minimize dust
• Wet feed
• Wet hay
• Ventilate barn
• Turnout as much as possible
• dac® Oil – Increased omega 3 to decrease
inflammation in the respiratory system
– Decrease dust particles in feed
COMMON EQUINE DISEASES – CAN dac® HELP? 21
HYPP
• Hyperkalemic Periodic Paralysis
• Genetic disorder
• Disrupted sodium channels
• Increased potassium in blood
• Excessive muscle contraction
COMMON EQUINE DISEASES – CAN dac® HELP? 22
HYPP
• Muscle twitching
• Paralysis
• Seizures
• Respiratory noise
• Sudden death
http://www.youtube.com/watch?v=GSLRhaRxFDU
COMMON EQUINE DISEASES – CAN dac® HELP? 23
HYPP
• Results of HYPP genetic test – nn
• normal
– nH • One copy of
defective gene
– HH • 2 copies of
defective gene, severely affected
COMMON EQUINE DISEASES – CAN dac® HELP? 24
HYPP
• Total diet potassium less than 1.2%
• No molasses, orchard grass hay, alfalfa products, wheat bran
• No Electrolytes
• Oats + vitamin & mineral
• dac® Orange Superior
COMMON EQUINE DISEASES – CAN dac® HELP? 25
EPM
• Equine Protozoal Myeloencephalitis
• Neurological disease
• Transmitted via opossum feces
• Caused by sarcocystis neurona parasite
• Need medication to suppress parasite
COMMON EQUINE DISEASES – CAN dac® HELP? 26
EPM • Symptoms
– Incoordination – Gait abnormalities – Head tilt – Facial nerve paralysis – Difficulty swallowing – Loss of sensation along
the face, neck and body – Weakness – Lameness – Weight loss – Blindness – Seizures
COMMON EQUINE DISEASES – CAN dac® HELP? 27
EPM
• Low NSC feed – Beet pulp
• Plenty of fiber
• High fat
• Good quality protein – Rebuild damaged muscle tissue – Alfalfa, soybean meal
• Vitamin E – Rebuild damaged nerves
Diarrhea is a side affect of medication
COMMON EQUINE DISEASES – CAN dac® HELP? 28
EPM
• dac® DDA
– fiber digestion, diarrhea
• dac® Oil
– Weight gain without grain
• dac® E & Se
– nerve rebuilding
• dac® Orange Superior
– If feeding unfortified ingredients
COMMON EQUINE DISEASES – CAN dac® HELP? 30
ULCERS – PERFORMANCE HORSES
GastricUlcers Colonic
Ulcers No UlcersGastric &ColonicUlcers
87%
63%
3%
54%
Pellegrini, 2005
COMMON EQUINE DISEASES – CAN dac® HELP? 31
ULCERS - CAUSES
• Increased Acidity
• Exercise Intensity
• Intermittent feeding
• Transport stress
• NSAID’s
• High Starch
– VFA’s, pH
COMMON EQUINE DISEASES – CAN dac® HELP? 32
ULCERS - GASTRIC
Margo Plicatus
Small Intestine
Esophagus
Pyloric Sphincter
COMMON EQUINE DISEASES – CAN dac® HELP? 33
ULCERS - GASTRIC
• Alfalfa
• Frequent meals
• Constant access to hay or pasture
• dac® DDA – to stimulate appetite
• dac® Oil – Weight gain without grain
COMMON EQUINE DISEASES – CAN dac® HELP? 34
ULCERS - COLONIC
• Less frequent but more severe than gastric ulcers
• Symptoms – Intermittent colic
– Lethargy
– Anorexia
– Fever
– Diarrhea
– Dehydration
– Ventral edema
COMMON EQUINE DISEASES – CAN dac® HELP? 35
ULCERS - COLONIC
• Pelleted/cubed forage
• Frank Andrews – Yeast Extract may help with colonic ulcers
– Stabilize hindgut pH
• Yeast extract is a key component of dac® DDA
• dac® Oil – Weight gain without grain
COMMON EQUINE DISEASES – CAN dac® HELP? 37
COLIC
• Impaction Colic – Dehydrated digestive tract
– dac® Electro-Aid
– dac® DDA
• Gas Colic – Gas build up – pain, most
common
– dac® DDA
– dac® Oil
COMMON EQUINE DISEASES – CAN dac® HELP? 38
KIDNEY DISEASE
• Loss of kidney function • Waste products will accumulate in the horse's
system, causing toxicity/poisoning • Can occur after:
– dehydration – Acute blood loss – Exercise-associated sweat losses – Sepsis
• Chronic • Acute
COMMON EQUINE DISEASES – CAN dac® HELP? 39
KIDNEY DISEASE
• Lethargy • Drinking excess amounts of
water • Urinating a lot • Discolored urine • Strong smelling urine • Toxins in blood can:
– Irritate the stomach – Anorexia – Depression
COMMON EQUINE DISEASES – CAN dac® HELP? 40
KIDNEY DISEASE
• Low protein – No legumes (alfalfa, clover), soybeans
• Low phosphorus – No Wheat bran
• Low calcium – No legumes (alfalfa, clover), no beet pulp
• Use Fat Supplements
• Electrolytes
• Plenty of fresh clean water
COMMON EQUINE DISEASES – CAN dac® HELP? 41
KIDNEY DISEASE
• No commercial grain concentrates
• Limited amount of whole or crimped oats
• Grass hay
• No ad lib salt – Add 1 to 2 oz. daily
• dac® Oil
• dac® Electro-Aid
• dac® DDA - enhance digestion of fiber, boost immune function
COMMON EQUINE DISEASES – CAN dac® HELP? 42
LIVER DISEASE
• Liver Dysfunction
• Lethargy
• Dark colored urine
• Itchy
COMMON EQUINE DISEASES – CAN dac® HELP? 43
LIVER DISEASE
• Unbalanced amino acids
– Decreased branched-chain amino acids (leucine, isoleucine, and valine)
– Increased aromatic amino acids (phenylalanine, tyrosine, and tryptophan)
• Ammonia production increases
COMMON EQUINE DISEASES – CAN dac® HELP? 44
LIVER DISEASE
• Meet energy without excess protein – Protein source should have high branched chain: aromatic
AA ratio
• Do not feed fat supplements • Readily available soluble carbohydrates are essential • 50% steam flaked corn + 50% grass hay
– Can add molasses
• Multiple small feeding to prevent ammonia surges • Avoid - Legume hays, oats, and soybeans because of
high levels of aromatic AA’s • Plenty of clean fresh water
COMMON EQUINE DISEASES – CAN dac® HELP? 45
LIVER DISEASE
• No dac® Oil
• Beet pulp
• Wheat Bran
• Steam Flaked Corn
• B-Vitamins
• Vitamin C
• dac® Yucca – Ammonia Production
• dac® DDA – enhance digestion of fiber, boost immune function
Correct AA ratio
dac® Orange Superior
COMMON EQUINE DISEASES – CAN dac® HELP? 46
QUESTIONS
Dr. Tania Cubitt – [email protected] dac® Office - [email protected]