cobiosa - impag.ch...cobiogum is compatible with a multitude of cosmetic raw materi-als, can be...
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Product Catalogue 2019
Cobiosa
1 / 12
Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives
Use level Solubility
BIO-CERAMI-DYL HAIR
*
Water (and) Glycerine (and) Glycosphingolipids (and) Phos-pholipids (and) Acrylates C10-30 Alkyl acrylate (and) Crosspolymer (and) Cholesterol (and) Sodium Hydroxide
Repairs dried and damaged hairs, Improving their scales cohesion, Restores the lipidic barrier at hairs
Improvement of hair strength ((2 % shampoo, 3 % hair mask), Increase in brightness (1 % shampoo)
Pheno-xyethanol
1 - 3 %
Hydrodisper-sible
BIO-CERAMI-DYL PURE
*
Glycosphingolipids (and) Phos-pholipids (and) Cholesterol
Skin barrier strengthener, Improves cohesion of skin and hair scales, Repairs rough and very dry skins, Atopic and sensitive skins
Regenerative effect on damaged skin (0.5 %, D7), Improvement of atopic dermatitis (0.5 %, D14)
None 0.2 - 0.5 %
Liposoluble & Hydrodisper-sible
CERAMIDYL OMEGA
*
Plukenetia volubilis seed oil (and) Glycerin (and) Water (and) Glycosphingolipids (and) Polyglyceryl-5 Oleate (and) Phos-pholids (and) Tocopheryl acetate (and) Cholesterol
Contains poly-unsaturated fatty acids and ceramides to preserve the stratum corneum and hair lipids, Reinforces the skin & hair barriers, Treatments for sensitive & dry skin, Weak & dry hair
Hydration (5 %, 2h, 4h), "Better moisturized skin, softer skin, bet-ter general feeling, oily skin felt mattified" (5 %, D28; Panelist's evaluation)
None 3 - 5 %
Hydrodisper-sible
HYACERAMI-DYL
*
Glycerin (and) Ceramides (and) Squalane (and) Pentylene Glycol (and) Sodium Hyaluronate
Ceramides liposomes with anhydrous hyaluronic acid, High skin compatibility, Moisturization, Firmness and anti-wrinkles activities
Moisturization, Reduction of wrinkle volume and total rough-ness (2 %, 15 min, D28)
None 0.3 - 3 %
Liposoluble & hydrodisper-sible
LIPO CERAMI-DYL 20
Ethylhexyl Stearate (and) Glycosphingolipids (and) Phos-pholipids (and) Methyl Glucose Isostearate (and) Cholesterol
Protection, Reinforces skin and hair scales
None 1 - 2.5 %
Liposoluble, Hydrodisper-sible
LIPO CERAVIT C
*
Glycerin (and) Ascorbyl tetraiso-palmitate (and) Ceramides (and) Pentylene glycol
High concentration of Vitamin C (20 %) at Ceramide liposomes, Stimulates collagen production, Skin lightening & Anti-Aging
Promotion of collagen synthesis, Melanin inhibition, Anti-free radical scavenger
None 0.5 - 3 %
Liposoluble & Hydrodisper-sible
PHYTO CERAMIDYL OMEGA
*
Plukenetia Volubilis Seed Oil (and) Olea Europaea Fruit Oil (and) Glycerin (and) Aqua (and) Poly-glyceryl-5 Oleate (and) Ceramide 3 (and) Tocopherol
Protective active, Supplies lipids for the skin's stratum corneum and for the hair, Reinfoces barrier function at skin & hair, Sensitive and mature dry skins
Improvement of skin elasticity after a single application (3 %, 5 %, 30 min, 1h, 2h), Improve-ment of skin elasticity (5 %, D7, D15, D30), Wrinkle reduction (5 %, D30), Improvement of skin smoothness (5 %, D7, D15, D30)
None 3 - 5 %
Hydrodisper-sible
SPHINGOLI-PIDS COB PF
Octyldodecanol (and) Phos-pholipids (and) Cholesterol (and) Glycosphingolipids (and) Tocopheryl Acetate
Lipo-protection and lipo-structuration, Film-forming effect on the labial membrane, Maintains lips turgidity and optimal hydro-retention and permanent lubrication, Lipidic conditioner for the hair and scalp
Pheno-xyethanol
2 - 5 %
Liposoluble, Hydrodisper-sible
CHINA approved * CHINA approved (other INCI : Glycosphingolipids)
CERAMIDES
2
COBIOPURE is an extract from the leaves of Moringa oleifera, who-se cultivation following Guarani tradition in Paraguay is biodynamic according to the Demeter standard. Demeter International is the lar-gest organization for certification of biodynamic agriculture.
Moringa, also known as the drumstick tree, is best known for the high nutrient content of its leaves. 18 out of 20 essential amino acids, high concentrations of vitamins A and C, and high content of sodium, iron and other important minerals can be found in the leaves of this miracle tree. Due to this unique composition, Moringa has been an integral part of indigenous medicine for hundreds of years and is still used as a modern “silver bullet” in health and beauty products.
The white, odourless powder COBIOGUM is obtained from the en-dosperm inside the seeds of the native Peruvian Caesalpina spinosa, also known as Tara, and has excellent gel-forming properties. COBI-OGUM is of 100% natural origin and therefore offers an alternative to chemical thickeners.
The main components of COBIOGUM are galactomannans, a class of polysaccharides of unique hydrocolloid nature that have wonderful rheological properties.
The innovative active ingredient Cobiolift has remarkable film-forming, moisturizing and tightening properties. The 100% natural active is a pure fraction extracted from quinoa seeds and has a 3D structure perfectly matching the skin’s surface. Cobiolift rests like a natural, cohesive film on the skin, where it tightens, smoothes and makes the skin radiant over a long time. Various in-vivo studies con-firm the immediate, the long-lasting, the tightening and the moistu-rizing properties of Cobiolift.
In a clinical trial, 15 volunteers applied an emulsion containing Co-biolift once in the crow’s feet area at one of three different concen-trations (3%, 1.5% and 0.5%). Wrinkle depth was analyzed by PRIMOS measurement and compared with the placebo results after 30 mi-nutes and after 1 hour.
The Moringa extract COBIOPURE exhibits strong antioxidative and protective activity: the phenolic antioxidants present in COBIOPURE inhibit free radicals and prevent cell damage (in-vitro). Furthermore, the Moringa extract reduces UV-induced inflammations and pro-tects skin and hair against photodamage.
COBIOPURE is suitable for anti-inflammatory and antioxidative cos-metic products, as well as for use in UV-protection (hair and skin), anti-pollution, and revitalization of skin. The extract is water-soluble, free of preservatives, and natural cosmetics compliant.
COBIOGUM is compatible with a multitude of cosmetic raw materi-als, can be worked in hot or cold, and is stable over a wide pH range. COBIOGUM leaves behind a silky feel to the skin, has the capability of storing moisture, and gels easily in water, making it an attractive ingredient for cosmetics.
COBIOGUM has a versatile range of applications in skin and hair care products. A clinical study showed that COBIOGUM significantly in-creases skin moisture compared to placebo.
In 60% of the volunteers, 30 minutes after application, Cobiolift exhi-bits an immediate wrinkle-smoothing effect of 19% already at a very low application concentration of 0.5%. This effect becomes stronger at increasing application concentration of Cobiolift: Wrinkle depth was reduced by 45% already 30 minutes after a single application of a test emulsion containing 3% Cobiolift.
Cobiolift is a natural tightening active that achieves significant skin smoothing after 30 minutes already at an application concentration of 0.5%.
COBIOPURE – Moringa extract for holistic care
COBIOGUM – Natural gelling agent
COBIOLIFT – Polysaccharide from quinoa seeds with immediate tensor effect
BOTANICALS
3
CHINA approved Cosmos approved
Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives
Use level Solubility
BIO-CAPIGEN VEG
Aqua (and) Hydrolyzed Soy Protein (and) Propanediol (and) Glycerin (and) Panthenol (and) Polyquaternium-11 (and) Propylene Glycol (and) Zinc PCA (and) Glucose (and) Ornithine HCL (and) Niacinamide (and) Arginine HCL(and) Panax Ginseng Root Extract (and) Citrulline (and) Glucosamine HCL (and) Pyridoxine HCl (and) Allium Cepa (Onion) Bulb Extract (and) Biotin
Anti hair-loss vegetal complex
Stimulation of keratin (KRT1) synthesis
Phen-oxye-thanol, Sorbic acid, Po-tassium sorbate, Sodium benzoate
3 - 10 %
Hydrosoluble
BIO-SLIM PF
Water (and) Glycerin (and) Escin (and) Propylene Glycol (and) PVP (and) Thre-onine (and) Caffeine (and) Theophylline (and) Tromethamine (and) Fucus Vesiculosus Extract (and) Laminaria Di-gitata Extract (and) Equisetum Arvense Extract (and) Hedera Helix (IVI) Extract
Anti-cellulite and firming, Improves drainage of tissues, Avoiding abnormal liquid retention, Stimulates tissues oxygenation and blood micro-circulation, Increases skin firmness
Phen-oxye-thanol, Sodium benzoate, Potas-sium sorbate
2 - 5 %
Hydrosoluble
C20 + COBI-OLIVE
Olea europea (Olive) Fruit Extract (and) Glycerin (and) Water
Anti-free radical, Anti-inflammatory, UV Protector, Collagen booster, Anti-stress
Anti-inflammatory and UV protective effects, Collagen stimulation effect
Protective and soothing on skin reddening and erytheme induced by UV (0.5 %, 1h, 2h, 24h)
None 0.2 - 1 %
Soluble in Glycerin, Propanediol, Alcohol
CHIA PROTECT
Salvia Hispanica Seed Oil Avoids hair color fading caused by UV, Improve-ment of hair gloss and shine after UV exposure, Calming and anti-redness effect on skin, Improve-ment of skin moisture and elasticity
Protection of hair color caused by UV (ex-vivo, 5 %), Restoration of hair gloss and shine after hair dyeing, bleaching and UV exposure (ex-vivo)
Immediate (4 %, 8 min) and longterm (4 %, D28) calming, Anti-redness and anti-itching effect, Skin elasticity improve-ment, TEWL reduction (4 %, D28)
None 1 - 5 %
Liposoluble
Cobioage
Propanediol (and) Aqua (and) Caesalpi-nia Spinosa Fruit Extract.
Protects from skin aging exposome, Anti-aging, Anti-wrinkle and firming, protection of collagen, elastin and hyaluronic acid, Anti-pollution, Antioxidant, Anti-glycosylation
Anti-wrinkle and firming effect, Anti-oxidant capacity, Anti-lipid peroxi-dation, Anti-glycation acti-vity, Anti-hyaluronidase and anti-collagenase activity
Anti-aging and reden-sifying efficacy (3 %, D56). Skin firmness, Elasticity, Thickness, Skin density improved (3 %, D56)
None 0.5 - 5 %
Hydrosoluble
COBIO-AHA
Water (and) Glycerin (and) Sodium Lac-tate (and) Glycolic Acid (and) Sucrose (and) Urea (and) Sodium Citrate (and) Malic Acid (and) Tartaric Acid
Synergic complex of Alpha Hydroxy Acids strengthened with moisturizing agents: Oligosaccharides and Urea, Main components of the NMF
Pheno-xyethanol
2 - 10 %
Hydrosoluble
BOTANICALS
4
CHINA approved Cosmos approved
Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives
Use level Solubility
Cobiobalance
Glycerin (and) Aqua (and) Polymnia Sonchifolia Root Juice
Prebiotic skincare, Preserves the skin microbiota, Skin comfort, Improves health and wellness of hair and scalp Simulates the skin's natural defense mecha-nisms
Helps in the regulation of the normal microbiota of the skin, maintaining its beneficial microflora, thanks to its prebiotic activity
Skin pH rebalancing capacity (5 %, D28)
None 1 - 10 %
Hydrosoluble
Cobiobright
Propanediol (and) Pouteria Lucuma Pulp Extract
Skin luminosity and brightness increasement, Anti-aging and skin repair properties, Pollu-tion protector, Prevents collagen degradation, Antioxidant
Brightening & depig-menting: Anti-Tyrosinase, Protection against the effects of environmental pollution because of antioxi-dant capacity
Skin brightening and skin luminosity increased (5 %, D28), "Skin is more hydrated, Skin color is more homogenous and skin is brighter" (5 %, D28; Panelist’s evaluation)
None 1- 5 %
Hydrosoluble
Cobiocare
Glycerin (and) Propolis Extract (and) Water
Natural treatments for acne and acneic lesions, Anti-microbial, Anti-bakterial, Anti-inflamma-tory properties
Bacterial inhibition test on some bacterial strains at different concentrations to determine respectively mini-mum Inhibitory Concentra-tion (MIC) and minimum Bactericidal Concentration (MCB)
Deodorizing Power (Sniff-test) (1.5 %, 8h, 24h); Reduction of acneic lesi-ons (4 %, D28; Panelist's evaluation)
None Antiodour produts: 1,5 % Treatment for acneic lesions: 4 %
Hydrosoluble
Cobiogum
Caesalpinia Spinosa Gum 100 % Natural gelling agent, Moisturizing & Film-forming active
Skin moisturizer (1 %, 30 min, 2h, 4h)
None 0.1 % - 2 %
Hydrosoluble
COBIOLIFT
Chenopodium Quinoa Seed Extract Natural polysaccharides extracted from the quinoa seeds with film forming characteristics to immediately reduce wrin-kles and skin roughness
Immediate wrinkle reduc-tion with stronger effects the higher the concentra-tion (0.5 %, 1.5 %, 3 %, 0 min, 30 min, 60 min)
None 0.5 - 3 %
Hydrosoluble
COBIO-PHY-TONIC
Propylene Glycol (and) Water (and) Hesperidin Methyl Chalcone (and) Malva Sylvestris (Mallow) Extract (and) Aesculus Hippocastanum (Horse Chest-nut) Seed Extract (and) Hamamelis Virginiana (Whitch Hazel) Extract (and) Ruscus Aculeatus Root Extract (and) Arnica Montana Flower Extract
Anti dark circle, Anti-eye bag treatement, De-congestive effect, Anti-irritant and calming
Improvement of blood circulation Lit.), Anti-in-flammatory and veno-tonic activity (lit.), Calming, decongestive and soothing (lit.), Anti-edema (lit.)
Anti-aye bag and anti-dark circles effect and roughness reduction (3 %, D28)
None 2 - 5 %
Hydro-soluble, Compatible with diluted ethanol, Insoluble in oils.
Cobiopure Propanediol (and) Water (and) Moringa Oleifera Leaf Extract.
The green treasure of the Guarani legacy for holistic skin & hair care
Anti-inflammatory activity, Skin anti-oxidant capacity in-vitro in keratinocytes, Anti-oxidant capacity on hair strands (ex-vivo)
None 1 % - 5 %
Hydrosoluble
BOTANICALS
5
CHINA approved Cosmos approved
Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives
Use level Solubility
COBIOWHITE
Aqua (and) Glycerin (and) Polysorbate 20 (and) Hamamelis Virginiana Leaf Extract (and) Coriandrum Sativum Fruit Extract (and) Olea Europaea Fruit Extract
Whitening, Photo-Aging, Anti-age spot treat-menet, Anti-oxidative, Anti-aging, Firming
Inhibition of melanogenesis and typosinase activity, Reduction og stress-induced reactive oxygen species (ROS), Inhibition of MMPs
Whitening (Dark spot lightening, Reduction of skin melanin, Hyperpig-mentation and spot size (1 %, D56)
None 0.5-2 %
Hydrosoluble
DRAGON'S BLOOD
Propanediol (and) Water (and) Croton lechleri resin powder
Promotes Collagen formation, Improves irritated skins, Anti-inflammatory, Anti-free radicals treatments
Wound healing "scratch test", Anti-free radical acti-vity, Stimulation of synthesis of defense genes GPX2, ALDH3B1 and AKR1C2, Stimulation of synthesis if the AQP3 gene encoding for Aquaporin-3
None 3 - 5 %
Hydrosoluble
DRAGON'S BLOOD LP
Butyrospermum Parkii Butter Extract (and) Argania Spinosa Kernel Oil (and) Croton Lechleri Resin Powder
Improves damaged and cracked lips, Ingredient formulated to be used at lipsticks and balms
Lip repairing activity (5 %, D7)
None 3 - 5 %
Liposoluble
GINSENG EXTRACT
Propanediol (and) Aqua (and) Panax Ginseng Root Extract
Ginseng extract with anti-aging, immunosti-mulatory and hair growth stimulatory activity
Anti-aging (Lit.), Anti-oxidant activity (Lit.), Immunostimulatory activity (Lit.), Hair grow stimulatory activity (Lit.)
None 3 % to 5 % in skin care formulation, 1 % to 3 % in hair lotion, 5 % to 10 % in anti hair loss formu-lation
Hydrosoluble
HYDRARGAN
Argania Spinosa Kernel Oil Regenerating & nourishing, Anti-free radicals, Skin smoother, Protective for skin and hair
None 3 - 5 %
Liposoluble
PHYTO DE-CONGESTIVE
Propylenglycol (and) Water (and) Alcohol Denat (and) Hesperidin Methyl Chalcone (and) Malva Sylvestris Mal-low) Extract (and) Aesculus Hippo-castanum (Horse Chestnut) Seed Extract (and) Hamamelis Virginiana (Whitch Hazel) Extract (and) Ruscus Aculeatus Root Extract (and) Arnica Montana Flower Extract
Calming complex, decongestive, Improves micro-circulation and reactive skins
None 2 - 5 %
Hydrosoluble & compatible with diluted ethanol
PORE-REDUC-TYL
Water (and) Butylene Glycol (and) Fomes Officinalis (mushroom) Extract
Natural astringent and cleanser, Immediate tightening effect, Red-uction of pore size and number, Maintains the skin moisture
Immediate decrease of pore number (3 %, 5 min, 10 min), Longlasting decrease of pore number (3 %, 1h )
Pheno-xyethanol
2 - 5 %
Hydrosoluble
BOTANICALS
6
CHINA approved Cosmos approved
Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives
Use level Solubility
PORE-REDUC-TYL NT
Propanediol (and) Aqua (and) Fomes Officinalis Extract
Natural astringent and cleanser, Immediate tightening effect, Red-uction of pore size and number, Maintains the skin moisture
Immediate decrease of pore number (3%, 5min, 10min), Longlasting decrease of pore number (3%, 1h )
Pheno-xyethanol
2 - 5 %
Hydrosoluble
RADIANCYL
Propanediol (and) Water (and) Lepidi-um Meyenii Root Extract
Energizer, Nutritive and firming effects on skin, Promotes collagen synthesis, Anti-hair loss and hair strengthening
Growth stimulation on human fibroblasts
Increase of hair thickness and decrease of vellus/hairs ratio (shampoo 2 %; intensive care ampoule 10 %, D56)
None 3 - 5 %
Hydrosoluble and soluble in alcohol
RED ONION EXTRACT PF
Propylene Glycol (and) Water (and) Allium Cepa (Onion) Bulb Extract
Antiseptic and skin soothing properties, Wounds and scars reducer, Hair growth stimulator
Sodium benzoate, Potas-sium sorbate
1 - 5 %
Hydrosoluble
SACHA INCI OMEGA BUTTER
Plukenetia Volubilis Seed Oil (and) C10-18 Triglycerides
Emollient, Moisturizer, Texturing agent, Protector of dry and sensitive skin
Hydration effectiveness and barrier protection versus Shea Butter (pure) (5 %, 2h, 4h, 8h)
None 1 - 100 %
Liposoluble
SACHA INCI OMEGA OIL
Plukenetia Volubilis Seed Oil Natural oil rich in omega 3, 6 and 9, main compo-nents of cell membranes. Increases skin resistance to external aggressions. For dry and sensitive skins
Decrease on TEWL value (5 %, D30), Skin restoring capacity vs Placebo (5 %, 2h, 4h), "Better moisturized, Softer, Better general feeling and oily skin felt matified (5 %, D30; Panelist's evaluation), Silicone-like skin effect
None 2 - 5 %
Liposoluble
SEBOREDUC-TYL
Water (and) Butylene Glycol (and) Hydrolyzed Yeast Protein (and) Fomes Officinalis (Mushroom) Extract (and) Pyridoxine (and) Niacinamide (and) Panthenol (and) Allantoin (and) Threo-nine (and) Biotin
Regulates sebum secre-tion, Decreases the pore size, Improves structure and comfort of oily skin and hair
Inhibition of 5α-reductase activity
Anti-sebum activity and pore size reduction (2 %, D14), "Global improvement of skin condtion", "Less oily skin" (2 %, D14; Panelist's evaluation)
Chlor-phenesin, Pheno-xyethanol
5 - 10 %
Hydrosoluble and soluble in alcohol
TRICHOMEGA
Plukenetia Volubilis Seed Oil Natural oil rich in unsatu-rated poly fatty acids and tocopherols to protect the hair from breakage and split
Reduction of hair breakage (1 %), Reduction of hair split (1 %) (tests on hair tresses)
None 1 - 2 %
Liposoluble
UNCARYL
Propanediol, (and) Water (and) Uncaria Tormentosa Extract
Improves inmunnological system, Anti-oxidant and cyto-protector, Anti-in-flammatory, Anti-aging, Collagen booster
None 3 - 5 %
Hydrosoluble
BOTANICALS
7
CHINA approved
Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives
Use level Solubility
AMINO GLYCO KVIAR
Water (and) Glycerin (and) Hydrolyzed Roe (and) Glycosami-noglycans (and) Glycogen
Nutrition, Energizing, Regenerating skin and moisturizing, Aged skin
Pheno-xyethanol, Methylpa-raben
1 - 2 %
Hydrosoluble
BIO-MARINE COLLAGEN 6
Soluble Collagen Nutrition of epidermis, Improves skin elasticity, Moisturizer and protector, Provides marine peptides and amino-acids"
Moisturizing effect on human horny layers
Chlor-phenesin, Methylpa-raben
0.5 - 5 %
Hydrosoluble
BIO-MARINE COLLAGEN 6 PH
Soluble Collagen Nutrition of epidermis, Improves skin elasticity, Moisturizer and protector, Provides marine peptides and amino-acids
Moisturizing effect on human horny layers
Phenoxye-thanol
0.5 - 5 %
Hydrosoluble
BIO-MARINE COLLAGEN HAIR
Soluble Collagen Filmogenic on hair damaged scales, Provides moisturization, protection & flexibility, Repairs damaged hairs
Repairing activity on damaged hair
Phenoxye-thanol
3 - 5 %
Hydrosoluble
BIO-MARINE ELASTIN
Hydrolyzed elastin Improves skin elasticity, Protector agent for skin and hair, Increases skin suppleness, Nutrition & regeneration
Pheno-xyethanol, Sorbic acid
5 %
Hydrosoluble
GLYCOENER-GIZER
Water (and) Glycerin (and) Glycogen
Energy source for skin cells, Promotes cell restora-tion and defense, stressed, dulled and tired skins
Growth stimulation on human fibro-blasts compared with epidermal growth factor
Pheno-xyethanol, Methylpa-raben
2 - 5 %
Hydrosoluble
HAIRDENSYL
Water (and) Soluble Collagen (and) Glycerin (and) Propylene Glycol (and) Honey (Mel) extract (and) Sodium PCA (and) Hydrolyzed elastin (and) Serine (and) Glycogen
Treatment to increase hair volume, Nutrition of hair follicles, Improves structure, Hair strengthner, Treatment for hair anti-aging, Helps to reduce hair loss
Protection to damaged hair
Phenozy-ethanol, Sorbic acid
5 - 10 %
Hydrosoluble
HYDRATENSYL COMPLEX
Water (and) Honey extract (and) Soluble Collagen (and) Hydrolyzed elastin (and) Sodium PCA (and) Serine (and) Glycogen
Special complex for skin nutrition, Moisturization and protection from marine & botanical origin
Pheno-xyethanol, Sorbic acid
3 - 5 %
Hydrosoluble
HYDRO MARI-NE COLLAGEN V10
Hydrolyzed Collagen Nutrition of epidermis, Improves elasticity, Moi-sturizing and protecting proteins
Pheno-xyethanol, Chlorphe-nesin
2 - 10 %
Hydrosoluble & soluble in glycols
OCEOVITAL GAG PF
Glycerin (and) Aqua (and) Glyco-saminoglycans (and) Glycogen
Stimulates oxygen consumption, Smoother and filmogenic, Restores energetic reserves, Anti-aging, Anti-stress, Moisturizing
Sodium Benzoate, Potassium sorbate
2 - 5 %
Hydrosoluble
MARINE
8
We live in a sea of invisible electronic pollution, and the level of electromagnetic radiation (EMR) has dramatically increased over the past decade. Awareness of its detrimental effects is also increasing.
Various studies show that the radiation from mobile telephones has a negative impact on skin. The constant radiation of mobi-le telephones induces hugely elevated production of free radicals (ROS), thus favouring inflammatory responses. These inflammatory responses invoke a massive increase in ATP, which leads to cellular degradation and mitochondrial damage.
The active ingredient Poly-Helixan PF is obtained from the secretion of the garden snail Helix aspersa. This species of snail has existed for 600 million years and has adapted to extreme climatic conditions.
When the snail goes into hibernation, a special secretion polymeri-zes and covers the entrance to its shell to protect the snail’s Body.
Snail farmers in Chile whose hands were frequently exposed to snail secretion discovered that their hands were smoother and that minor wounds would heal faster. This led to the development of the first cream containing snail secretion.
The active ingredient Poly-Helixan PF is a rich complex for skin rege-neration. It is rich in calcium carbonate.
With Cobiodefender EMR, our partner Cobiosa has developed the first active ingredient that protects the skin against the damages of electromagnetic radiation and neutralizes the negative impact of electronic pollution (e-smog).
Cobiodefender EMR reduces the oxidative stress induced by EMR in keratinocytes and reduces excessive accumulation of ATPs (in-vitro). Further tests are being conducted to substantiate these results.
COBIODEFENDER EMR – Protecting the skin against electromagnetic radiation
POLY-HELIXAN PF – Rich, skin-regenerating snail-secretion complex
Composition of Poly-Helixan PF:• Allantoin: Stimulates skin regeneration and possesses regenerative
and anti-inflammatory effects
• Proteins: Nourishing, smoothing and skin texture-improving properties
• Vitamins A, C and E: Stimulates collagen synthesis and skin Regeneration
• Mucopolysaccharides: Moisturizing effect, protects the skin against external stress
• Proteolytic enzymes: Supports the protease/anti-protease
• Balance
• Collagen and elastin: Components of connective tissue
Poly-Helixan PF was tested on 15 volunteers aged between 13 and 55 with scars. The volunteers applied a cosmetic formulation contai-ning 5% Poly-Helixan PF twice daily in the scar area. The measure-ments of skin elasticity (Cutometer) and skin moisture content (Cor-neometer) were taken before and then 30 days after application. The scars were also assessed by video microscopy on Day 0 and on Day 30.
The Cutometer and Corneometer measurements revealed a 32% in-crease in skin elasticity and a 17% increase in skin moisture content. Furthermore, a visible improvement of the scars was observed after 30 days of treatment with 5% Poly-Helixan PF. (Illustration upon re-quest).
Poly-Helixan PF is suitable for applications in the areas of anti-aging, after-sun, aftershave, post-depilation skin care, impure skin and moi-sturizing care.
MARINE
SPECIALTIES
9
CHINA approved
Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives
Use level Solubility
BIO-CAPIGEN PT
Placental Protein (and) Hydrolyzed Soy Protein (and) Propylene Glycol (and) Panthenol (and) Zinc PCA (and) Glucose (and) Ornithine HCL (and) Niacinamide (and) Arginine HCL (and) Pyridoxine (and) Glucosamine HCL (and) Citruline (and) Biotin
Anti-hair loss active, Improves the hair quality, Strong nutrient for hair health
Improvement of hair density and thickness (2 % Shampoo, 10 % intensive care ampoule, D56), "Hair has more volume and is stronger. The hair loss is reduced during day and while washing" (2 % Sham-poo, 10 % intensive care ampoule, D56; Panelist's evaluation)
Chlorphene-sin, Pheno-xyethanol, Sorbic acid
3 - 10 %
Hydrosoluble
BIO-COLLA-GEN V50
Hydrolized collagen Nutrition of epidermis, Improves elasticity, Moi-sturizing and protecting proteins, Firming
Chlorphene-sin, Sodium deydroace-tate
0.5 - 5 %
Hydrosoluble & soluble in glycols
BIO-HYDRAC-TYL
Water (and) Honey Extract (and) Sodium PCA (and) Serine (and) Glycogen
Hydro-regulator with analogous composition as skin's NMF, Improves water holding capacity of skin, Moisturizer
Skin hydration (ex-vivo) Skin hydration (5 %, 1h)
Phenoxye-thanol
3 - 10 %
Hydrosoluble
BIO-KERATIN PF
Water (and) Hydrolyzed Keratin
Restores cohesion of cuticulary scales, Improves hair's resistance, Hair conditioner, Nutritive for skin, hair and nails
Hair repair Sodium benzoate
5 - 10 %
Hydrosoluble
BIO-NUTRYL Amniotic Fluid Provides hydration and nutrition to the skin and hair, Natural detergent
Methyl-paraben , Hexametilen-trietamine, Sorbic acid
5 - 10 %
Hydrosoluble & soluble in alcohol (max.30º)
BIO-PROTEIN-OL PF
Placental Protein Stimulates oxygen con-sumption and metabolic processes, Strong nutrient, Anti-hair loss, Skin lightener
Stimulation of the oxygen consump-tion of epithelial cells
Chlorphe-nesin
5 - 10 %
Hydrosoluble & soluble in alcohol (max.30º)
BIOSPONGE HYDRACTYL
Honey Extract (and) Sodium PCA (and) Serine (and) Glycogen (and) Nylon 12 (and) Water
Micro-sponges acting as micro vectors for active, Chrono-cosmetics, Long moisturizing treatment, Improves water holding capacity of skin
Phenoxye-thanol
3 - 10 %
Insoluble in oils and water
SPECIALTIES
10
CHINA approved
Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives
Use level Solubility
COBIODEFEN-DER EMR
Aqua (and) Glycerin (and) Glycogen
Electromagnetic Defense Prevention of EMR induced ROS and ATP accumulation, Induction of expression of HSP70 (cytoprotective protein), Reduction of apoptosis in skin cells (ex-vivo), Prevention of desquamation of the stratum cor-neum (ex-vivo), Promotes synthesis of P53 by inducing miR-29b-3p in keratinocytes, Upregulation of fi-bronectin, Reduction of H3K79me3, H3K27me3, H3K9me3 histones
Phenoxye-thanol
2 - 6 %
Hydrosoluble
COBIODEFEN-DER EMR CHL
Aqua (and) Glycerin (and) Glycogen
Electromagnetic Defense Prevention of EMR induced ROS and ATP accumulation, Induction of expression of HSP70 (cytoprotective protein), Reduction of apoptosis in skin cells (ex-vivo), Prevention of desquamation of the stratum cor-neum (ex-vivo), Promotes synthesis of P53 by inducing miR-29b-3p in keratinocytes, Upregulation of fi-bronectin, Reduction of H3K79me3, H3K27me3, H3K9me3 histones
Chlorphe-nesin
2 - 6 %
Hydrosoluble
COBIOREPAIR WGC
Aqua (and) Umbilical Extract Synergistic mixture of con-centrated highly bioactive sulphated glycosamino-glycans (GAGs) of low molecular weight + HA of high and low molecular weight
Anti-oxidant protection on fibroblasts and keratinocytes, Cell chemo-attractive properties, Restoration of cellular matrix, Preservation of cell viability and morphology
Increase of epi-dermal thickness, Keratinocyte number, Collagen III fibers and elastic fibers (0.2 %, D90)
Phenoxye-thanol
0.2 - 3 %
Hydrosoluble
COBIOSTAB 400
Propylene Glycol (and) Hexamidine Diisethionate (and) Water
Hydro-soluble preservative system, Anti-dandruff and aseptizer
Anti-dandruff and anti-desquamation (1.25 %, D7, D14, D28)
Propylene glycol, Hexamidine Diisethionate
0.5 - 1.25 %
Hydrosoluble & soluble in ethanol
HAIR DANDRUFF REDUCER
Propylene Glycol (and) Hexamidine Diisethionate (and) Water
Antiseptic agent for skin and hair, Antimicrobial action against Pityrospo-rum ovale
Anti-dandruff and anti-desquamation (1.25 %, D7, D14, D28)
Propylene glycol, Hexamidine Diisethionate
0.5 - 1.25 %
Hydrosoluble (40-70 ºC) & in ethanol
HENTOWHITE AF
Polysorbate 20 (and) Hexyl-resorcinol (and) Caprylic Acid (and) Isopropyl Alcohol (and) Peg-400 (and) Caproic Acid (and) Capric Acid
Whitening care, Age Spot treatment, Photo-aging. Lightening
Inhibition of tyrosinase activity, Inhibition of melanin synthesis (ex-vivo)
Whitening (0.5 %, D28), "Spots are lighter, skin tone more uniform, skin looks healthier, spots are less percepti-ble" (0.5 %, D28; panelist's evaluation)
None 1 - 3 %
Hydrosoluble
KERATOPEEL Sucrose (and) Silica (and) Keratinase
Enzymatic peeling, Promotes the skin cell regeneration and renewal, Improves the acne and keratosis pilaris
Renewing effect (1 %, D15), Exfoliating effect (1 % D21)
None 2 %
Hydrosoluble
SPECIALTIES
11
2019 | 06
Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives
Use level Solubility
LIPOSOMES KERATIN PF
Water (and) Glycerin (and) Sorbitol (and) Hydrolyzed Keratin (and) Lecithin (and) Caprylyl glycol (and) Xanthan gum
Liposomes loaded with Hydrolyzed Keratin at 20 %
Delipidated hair treated with keratin Sodium benzoate
1 - 5 %
Hydrosoluble
NEO-HELIXAN
Water (and) Snail Secretion Filtrate (and) Propylene Glycol (and) Glycerine (and) Glyco-saminoglycans (and) Allantoin (and) Hydrolyzed Collagen (and) Pyridoxine HCL
Skin repair and regenera-tor, Anti-aging complex, Increases skin elasticity and protection
Visible improvement of scars and skin elasticity (5 %, D30)
Pheno-xyethanol, Imidazolidi-nyl urea, Me-thylparaben, Ethylparaben, Propylpara-ben, Butylpa-raben
1 - 5 %
Hydrosoluble, Soluble with tensio-actives and alcohol mixtures
NEO-HELIXAN PF
Water (and) Snail Secretion Filtrate (and) Propylene Glycol (and) Glycerine (and) Glyco-saminoglycans (and) Allantoin (and) Hydrolyzed Collagen (and) Pyridoxine HCL
Skin repair and regenera-tor, Anti-aging complex, Increases skin elasticity and protection
Visible improvement of scars and skin elasticity (5 %, D30)
Phenoxye-thanol
1 - 5 %
Hydrosoluble, Soluble with tensio-actives and alcohol mixtures
POLY-HELIXAN PF
Snail secretion filtrate Skin repairs and rege-nerator, Stretch marks, Increases skin elasticity and protection, Improves skin healing
Visible improvement of scars and skin elasticity (5 %, D30)
Phenoxye-thanol
2 - 5 %
Hydrosoluble
Based on 45 years of experience, Cobiosa develops and manufactures efficient active ingredients for skin care and hair care applications.
The independent company Cobiosa is specialized in the extraction, isolation and purification of various proteins, amino acids, polypep-tides, glycolipids, enzymes and other complexes, and has many years of experience in the manufacture of cosmetic products for third par-ties.
This makes Cobiosa a renowned actives manufacturer with exten-sive know-how in development, production and marketing.
Cobiosa offers support in the registration of cosmetic products, con-ducts stability tests, guarantees the high quality of its raw materials and offers an exciting product portfolio of versatile cosmetic active ingredients.
CHINA approved
Distributed byIMPAG AGRäffelstrasse 128045 ZurichSwitzerland
Phone: +41 43 499 25 00 Fax: +41 43 499 25 01E-Mail: [email protected]: www.impag.ch
IMPAG Group Country OfficesSwitzerland / Zurich – www.impag.chGermany / Offenbach – www.impag.deFrance / Nancy – www.impag.frPoland / Warsaw – www.impag.plAustria / Vienna – www.impag.at
IMPAG Group Head OfficeSwitzerland / Zurich
SPECIALTIES
Natural, effective cosmetic actives
COBIOSA