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Page 1: Cobiosa - impag.ch...COBIOGUM is compatible with a multitude of cosmetic raw materi-als, can be worked in hot or cold, and is stable over a wide pH range. COBIOGUM leaves behind a

Product Catalogue 2019

Cobiosa

1 / 12

Page 2: Cobiosa - impag.ch...COBIOGUM is compatible with a multitude of cosmetic raw materi-als, can be worked in hot or cold, and is stable over a wide pH range. COBIOGUM leaves behind a

Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives

Use level Solubility

BIO-CERAMI-DYL HAIR

*

Water (and) Glycerine (and) Glycosphingolipids (and) Phos-pholipids (and) Acrylates C10-30 Alkyl acrylate (and) Crosspolymer (and) Cholesterol (and) Sodium Hydroxide

Repairs dried and damaged hairs, Improving their scales cohesion, Restores the lipidic barrier at hairs

Improvement of hair strength ((2 % shampoo, 3 % hair mask), Increase in brightness (1 % shampoo)

Pheno-xyethanol

1 - 3 %

Hydrodisper-sible

BIO-CERAMI-DYL PURE

*

Glycosphingolipids (and) Phos-pholipids (and) Cholesterol

Skin barrier strengthener, Improves cohesion of skin and hair scales, Repairs rough and very dry skins, Atopic and sensitive skins

Regenerative effect on damaged skin (0.5 %, D7), Improvement of atopic dermatitis (0.5 %, D14)

None 0.2 - 0.5 %

Liposoluble & Hydrodisper-sible

CERAMIDYL OMEGA

*

Plukenetia volubilis seed oil (and) Glycerin (and) Water (and) Glycosphingolipids (and) Polyglyceryl-5 Oleate (and) Phos-pholids (and) Tocopheryl acetate (and) Cholesterol

Contains poly-unsaturated fatty acids and ceramides to preserve the stratum corneum and hair lipids, Reinforces the skin & hair barriers, Treatments for sensitive & dry skin, Weak & dry hair

Hydration (5 %, 2h, 4h), "Better moisturized skin, softer skin, bet-ter general feeling, oily skin felt mattified" (5 %, D28; Panelist's evaluation)

None 3 - 5 %

Hydrodisper-sible

HYACERAMI-DYL

*

Glycerin (and) Ceramides (and) Squalane (and) Pentylene Glycol (and) Sodium Hyaluronate

Ceramides liposomes with anhydrous hyaluronic acid, High skin compatibility, Moisturization, Firmness and anti-wrinkles activities

Moisturization, Reduction of wrinkle volume and total rough-ness (2 %, 15 min, D28)

None 0.3 - 3 %

Liposoluble & hydrodisper-sible

LIPO CERAMI-DYL 20

Ethylhexyl Stearate (and) Glycosphingolipids (and) Phos-pholipids (and) Methyl Glucose Isostearate (and) Cholesterol

Protection, Reinforces skin and hair scales

None 1 - 2.5 %

Liposoluble, Hydrodisper-sible

LIPO CERAVIT C

*

Glycerin (and) Ascorbyl tetraiso-palmitate (and) Ceramides (and) Pentylene glycol

High concentration of Vitamin C (20 %) at Ceramide liposomes, Stimulates collagen production, Skin lightening & Anti-Aging

Promotion of collagen synthesis, Melanin inhibition, Anti-free radical scavenger

None 0.5 - 3 %

Liposoluble & Hydrodisper-sible

PHYTO CERAMIDYL OMEGA

*

Plukenetia Volubilis Seed Oil (and) Olea Europaea Fruit Oil (and) Glycerin (and) Aqua (and) Poly-glyceryl-5 Oleate (and) Ceramide 3 (and) Tocopherol

Protective active, Supplies lipids for the skin's stratum corneum and for the hair, Reinfoces barrier function at skin & hair, Sensitive and mature dry skins

Improvement of skin elasticity after a single application (3 %, 5 %, 30 min, 1h, 2h), Improve-ment of skin elasticity (5 %, D7, D15, D30), Wrinkle reduction (5 %, D30), Improvement of skin smoothness (5 %, D7, D15, D30)

None 3 - 5 %

Hydrodisper-sible

SPHINGOLI-PIDS COB PF

Octyldodecanol (and) Phos-pholipids (and) Cholesterol (and) Glycosphingolipids (and) Tocopheryl Acetate

Lipo-protection and lipo-structuration, Film-forming effect on the labial membrane, Maintains lips turgidity and optimal hydro-retention and permanent lubrication, Lipidic conditioner for the hair and scalp

Pheno-xyethanol

2 - 5 %

Liposoluble, Hydrodisper-sible

CHINA approved * CHINA approved (other INCI : Glycosphingolipids)

CERAMIDES

2

Page 3: Cobiosa - impag.ch...COBIOGUM is compatible with a multitude of cosmetic raw materi-als, can be worked in hot or cold, and is stable over a wide pH range. COBIOGUM leaves behind a

COBIOPURE is an extract from the leaves of Moringa oleifera, who-se cultivation following Guarani tradition in Paraguay is biodynamic according to the Demeter standard. Demeter International is the lar-gest organization for certification of biodynamic agriculture.

Moringa, also known as the drumstick tree, is best known for the high nutrient content of its leaves. 18 out of 20 essential amino acids, high concentrations of vitamins A and C, and high content of sodium, iron and other important minerals can be found in the leaves of this miracle tree. Due to this unique composition, Moringa has been an integral part of indigenous medicine for hundreds of years and is still used as a modern “silver bullet” in health and beauty products.

The white, odourless powder COBIOGUM is obtained from the en-dosperm inside the seeds of the native Peruvian Caesalpina spinosa, also known as Tara, and has excellent gel-forming properties. COBI-OGUM is of 100% natural origin and therefore offers an alternative to chemical thickeners.

The main components of COBIOGUM are galactomannans, a class of polysaccharides of unique hydrocolloid nature that have wonderful rheological properties.

The innovative active ingredient Cobiolift has remarkable film-forming, moisturizing and tightening properties. The 100% natural active is a pure fraction extracted from quinoa seeds and has a 3D structure perfectly matching the skin’s surface. Cobiolift rests like a natural, cohesive film on the skin, where it tightens, smoothes and makes the skin radiant over a long time. Various in-vivo studies con-firm the immediate, the long-lasting, the tightening and the moistu-rizing properties of Cobiolift.

In a clinical trial, 15 volunteers applied an emulsion containing Co-biolift once in the crow’s feet area at one of three different concen-trations (3%, 1.5% and 0.5%). Wrinkle depth was analyzed by PRIMOS measurement and compared with the placebo results after 30 mi-nutes and after 1 hour.

The Moringa extract COBIOPURE exhibits strong antioxidative and protective activity: the phenolic antioxidants present in COBIOPURE inhibit free radicals and prevent cell damage (in-vitro). Furthermore, the Moringa extract reduces UV-induced inflammations and pro-tects skin and hair against photodamage.

COBIOPURE is suitable for anti-inflammatory and antioxidative cos-metic products, as well as for use in UV-protection (hair and skin), anti-pollution, and revitalization of skin. The extract is water-soluble, free of preservatives, and natural cosmetics compliant.

COBIOGUM is compatible with a multitude of cosmetic raw materi-als, can be worked in hot or cold, and is stable over a wide pH range. COBIOGUM leaves behind a silky feel to the skin, has the capability of storing moisture, and gels easily in water, making it an attractive ingredient for cosmetics.

COBIOGUM has a versatile range of applications in skin and hair care products. A clinical study showed that COBIOGUM significantly in-creases skin moisture compared to placebo.

In 60% of the volunteers, 30 minutes after application, Cobiolift exhi-bits an immediate wrinkle-smoothing effect of 19% already at a very low application concentration of 0.5%. This effect becomes stronger at increasing application concentration of Cobiolift: Wrinkle depth was reduced by 45% already 30 minutes after a single application of a test emulsion containing 3% Cobiolift.

Cobiolift is a natural tightening active that achieves significant skin smoothing after 30 minutes already at an application concentration of 0.5%.

COBIOPURE – Moringa extract for holistic care

COBIOGUM – Natural gelling agent

COBIOLIFT – Polysaccharide from quinoa seeds with immediate tensor effect

BOTANICALS

3

Page 4: Cobiosa - impag.ch...COBIOGUM is compatible with a multitude of cosmetic raw materi-als, can be worked in hot or cold, and is stable over a wide pH range. COBIOGUM leaves behind a

CHINA approved Cosmos approved

Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives

Use level Solubility

BIO-CAPIGEN VEG

Aqua (and) Hydrolyzed Soy Protein (and) Propanediol (and) Glycerin (and) Panthenol (and) Polyquaternium-11 (and) Propylene Glycol (and) Zinc PCA (and) Glucose (and) Ornithine HCL (and) Niacinamide (and) Arginine HCL(and) Panax Ginseng Root Extract (and) Citrulline (and) Glucosamine HCL (and) Pyridoxine HCl (and) Allium Cepa (Onion) Bulb Extract (and) Biotin

Anti hair-loss vegetal complex

Stimulation of keratin (KRT1) synthesis

Phen-oxye-thanol, Sorbic acid, Po-tassium sorbate, Sodium benzoate

3 - 10 %

Hydrosoluble

BIO-SLIM PF

Water (and) Glycerin (and) Escin (and) Propylene Glycol (and) PVP (and) Thre-onine (and) Caffeine (and) Theophylline (and) Tromethamine (and) Fucus Vesiculosus Extract (and) Laminaria Di-gitata Extract (and) Equisetum Arvense Extract (and) Hedera Helix (IVI) Extract

Anti-cellulite and firming, Improves drainage of tissues, Avoiding abnormal liquid retention, Stimulates tissues oxygenation and blood micro-circulation, Increases skin firmness

Phen-oxye-thanol, Sodium benzoate, Potas-sium sorbate

2 - 5 %

Hydrosoluble

C20 + COBI-OLIVE

Olea europea (Olive) Fruit Extract (and) Glycerin (and) Water

Anti-free radical, Anti-inflammatory, UV Protector, Collagen booster, Anti-stress

Anti-inflammatory and UV protective effects, Collagen stimulation effect

Protective and soothing on skin reddening and erytheme induced by UV (0.5 %, 1h, 2h, 24h)

None 0.2 - 1 %

Soluble in Glycerin, Propanediol, Alcohol

CHIA PROTECT

Salvia Hispanica Seed Oil Avoids hair color fading caused by UV, Improve-ment of hair gloss and shine after UV exposure, Calming and anti-redness effect on skin, Improve-ment of skin moisture and elasticity

Protection of hair color caused by UV (ex-vivo, 5 %), Restoration of hair gloss and shine after hair dyeing, bleaching and UV exposure (ex-vivo)

Immediate (4 %, 8 min) and longterm (4 %, D28) calming, Anti-redness and anti-itching effect, Skin elasticity improve-ment, TEWL reduction (4 %, D28)

None 1 - 5 %

Liposoluble

Cobioage

Propanediol (and) Aqua (and) Caesalpi-nia Spinosa Fruit Extract.

Protects from skin aging exposome, Anti-aging, Anti-wrinkle and firming, protection of collagen, elastin and hyaluronic acid, Anti-pollution, Antioxidant, Anti-glycosylation

Anti-wrinkle and firming effect, Anti-oxidant capacity, Anti-lipid peroxi-dation, Anti-glycation acti-vity, Anti-hyaluronidase and anti-collagenase activity

Anti-aging and reden-sifying efficacy (3 %, D56). Skin firmness, Elasticity, Thickness, Skin density improved (3 %, D56)

None 0.5 - 5 %

Hydrosoluble

COBIO-AHA

Water (and) Glycerin (and) Sodium Lac-tate (and) Glycolic Acid (and) Sucrose (and) Urea (and) Sodium Citrate (and) Malic Acid (and) Tartaric Acid

Synergic complex of Alpha Hydroxy Acids strengthened with moisturizing agents: Oligosaccharides and Urea, Main components of the NMF

Pheno-xyethanol

2 - 10 %

Hydrosoluble

BOTANICALS

4

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CHINA approved Cosmos approved

Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives

Use level Solubility

Cobiobalance

Glycerin (and) Aqua (and) Polymnia Sonchifolia Root Juice

Prebiotic skincare, Preserves the skin microbiota, Skin comfort, Improves health and wellness of hair and scalp Simulates the skin's natural defense mecha-nisms

Helps in the regulation of the normal microbiota of the skin, maintaining its beneficial microflora, thanks to its prebiotic activity

Skin pH rebalancing capacity (5 %, D28)

None 1 - 10 %

Hydrosoluble

Cobiobright

Propanediol (and) Pouteria Lucuma Pulp Extract

Skin luminosity and brightness increasement, Anti-aging and skin repair properties, Pollu-tion protector, Prevents collagen degradation, Antioxidant

Brightening & depig-menting: Anti-Tyrosinase, Protection against the effects of environmental pollution because of antioxi-dant capacity

Skin brightening and skin luminosity increased (5 %, D28), "Skin is more hydrated, Skin color is more homogenous and skin is brighter" (5 %, D28; Panelist’s evaluation)

None 1- 5 %

Hydrosoluble

Cobiocare

Glycerin (and) Propolis Extract (and) Water

Natural treatments for acne and acneic lesions, Anti-microbial, Anti-bakterial, Anti-inflamma-tory properties

Bacterial inhibition test on some bacterial strains at different concentrations to determine respectively mini-mum Inhibitory Concentra-tion (MIC) and minimum Bactericidal Concentration (MCB)

Deodorizing Power (Sniff-test) (1.5 %, 8h, 24h); Reduction of acneic lesi-ons (4 %, D28; Panelist's evaluation)

None Antiodour produts: 1,5 % Treatment for acneic lesions: 4 %

Hydrosoluble

Cobiogum

Caesalpinia Spinosa Gum 100 % Natural gelling agent, Moisturizing & Film-forming active

Skin moisturizer (1 %, 30 min, 2h, 4h)

None 0.1 % - 2 %

Hydrosoluble

COBIOLIFT

Chenopodium Quinoa Seed Extract Natural polysaccharides extracted from the quinoa seeds with film forming characteristics to immediately reduce wrin-kles and skin roughness

Immediate wrinkle reduc-tion with stronger effects the higher the concentra-tion (0.5 %, 1.5 %, 3 %, 0 min, 30 min, 60 min)

None 0.5 - 3 %

Hydrosoluble

COBIO-PHY-TONIC

Propylene Glycol (and) Water (and) Hesperidin Methyl Chalcone (and) Malva Sylvestris (Mallow) Extract (and) Aesculus Hippocastanum (Horse Chest-nut) Seed Extract (and) Hamamelis Virginiana (Whitch Hazel) Extract (and) Ruscus Aculeatus Root Extract (and) Arnica Montana Flower Extract

Anti dark circle, Anti-eye bag treatement, De-congestive effect, Anti-irritant and calming

Improvement of blood circulation Lit.), Anti-in-flammatory and veno-tonic activity (lit.), Calming, decongestive and soothing (lit.), Anti-edema (lit.)

Anti-aye bag and anti-dark circles effect and roughness reduction (3 %, D28)

None 2 - 5 %

Hydro-soluble, Compatible with diluted ethanol, Insoluble in oils.

Cobiopure Propanediol (and) Water (and) Moringa Oleifera Leaf Extract.

The green treasure of the Guarani legacy for holistic skin & hair care

Anti-inflammatory activity, Skin anti-oxidant capacity in-vitro in keratinocytes, Anti-oxidant capacity on hair strands (ex-vivo)

None 1 % - 5 %

Hydrosoluble

BOTANICALS

5

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CHINA approved Cosmos approved

Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives

Use level Solubility

COBIOWHITE

Aqua (and) Glycerin (and) Polysorbate 20 (and) Hamamelis Virginiana Leaf Extract (and) Coriandrum Sativum Fruit Extract (and) Olea Europaea Fruit Extract

Whitening, Photo-Aging, Anti-age spot treat-menet, Anti-oxidative, Anti-aging, Firming

Inhibition of melanogenesis and typosinase activity, Reduction og stress-induced reactive oxygen species (ROS), Inhibition of MMPs

Whitening (Dark spot lightening, Reduction of skin melanin, Hyperpig-mentation and spot size (1 %, D56)

None 0.5-2 %

Hydrosoluble

DRAGON'S BLOOD

Propanediol (and) Water (and) Croton lechleri resin powder

Promotes Collagen formation, Improves irritated skins, Anti-inflammatory, Anti-free radicals treatments

Wound healing "scratch test", Anti-free radical acti-vity, Stimulation of synthesis of defense genes GPX2, ALDH3B1 and AKR1C2, Stimulation of synthesis if the AQP3 gene encoding for Aquaporin-3

None 3 - 5 %

Hydrosoluble

DRAGON'S BLOOD LP

Butyrospermum Parkii Butter Extract (and) Argania Spinosa Kernel Oil (and) Croton Lechleri Resin Powder

Improves damaged and cracked lips, Ingredient formulated to be used at lipsticks and balms

Lip repairing activity (5 %, D7)

None 3 - 5 %

Liposoluble

GINSENG EXTRACT

Propanediol (and) Aqua (and) Panax Ginseng Root Extract

Ginseng extract with anti-aging, immunosti-mulatory and hair growth stimulatory activity

Anti-aging (Lit.), Anti-oxidant activity (Lit.), Immunostimulatory activity (Lit.), Hair grow stimulatory activity (Lit.)

None 3 % to 5 % in skin care formulation, 1 % to 3 % in hair lotion, 5 % to 10 % in anti hair loss formu-lation

Hydrosoluble

HYDRARGAN

Argania Spinosa Kernel Oil Regenerating & nourishing, Anti-free radicals, Skin smoother, Protective for skin and hair

None 3 - 5 %

Liposoluble

PHYTO DE-CONGESTIVE

Propylenglycol (and) Water (and) Alcohol Denat (and) Hesperidin Methyl Chalcone (and) Malva Sylvestris Mal-low) Extract (and) Aesculus Hippo-castanum (Horse Chestnut) Seed Extract (and) Hamamelis Virginiana (Whitch Hazel) Extract (and) Ruscus Aculeatus Root Extract (and) Arnica Montana Flower Extract

Calming complex, decongestive, Improves micro-circulation and reactive skins

None 2 - 5 %

Hydrosoluble & compatible with diluted ethanol

PORE-REDUC-TYL

Water (and) Butylene Glycol (and) Fomes Officinalis (mushroom) Extract

Natural astringent and cleanser, Immediate tightening effect, Red-uction of pore size and number, Maintains the skin moisture

Immediate decrease of pore number (3 %, 5 min, 10 min), Longlasting decrease of pore number (3 %, 1h )

Pheno-xyethanol

2 - 5 %

Hydrosoluble

BOTANICALS

6

Page 7: Cobiosa - impag.ch...COBIOGUM is compatible with a multitude of cosmetic raw materi-als, can be worked in hot or cold, and is stable over a wide pH range. COBIOGUM leaves behind a

CHINA approved Cosmos approved

Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives

Use level Solubility

PORE-REDUC-TYL NT

Propanediol (and) Aqua (and) Fomes Officinalis Extract

Natural astringent and cleanser, Immediate tightening effect, Red-uction of pore size and number, Maintains the skin moisture

Immediate decrease of pore number (3%, 5min, 10min), Longlasting decrease of pore number (3%, 1h )

Pheno-xyethanol

2 - 5 %

Hydrosoluble

RADIANCYL

Propanediol (and) Water (and) Lepidi-um Meyenii Root Extract

Energizer, Nutritive and firming effects on skin, Promotes collagen synthesis, Anti-hair loss and hair strengthening

Growth stimulation on human fibroblasts

Increase of hair thickness and decrease of vellus/hairs ratio (shampoo 2 %; intensive care ampoule 10 %, D56)

None 3 - 5 %

Hydrosoluble and soluble in alcohol

RED ONION EXTRACT PF

Propylene Glycol (and) Water (and) Allium Cepa (Onion) Bulb Extract

Antiseptic and skin soothing properties, Wounds and scars reducer, Hair growth stimulator

Sodium benzoate, Potas-sium sorbate

1 - 5 %

Hydrosoluble

SACHA INCI OMEGA BUTTER

Plukenetia Volubilis Seed Oil (and) C10-18 Triglycerides

Emollient, Moisturizer, Texturing agent, Protector of dry and sensitive skin

Hydration effectiveness and barrier protection versus Shea Butter (pure) (5 %, 2h, 4h, 8h)

None 1 - 100 %

Liposoluble

SACHA INCI OMEGA OIL

Plukenetia Volubilis Seed Oil Natural oil rich in omega 3, 6 and 9, main compo-nents of cell membranes. Increases skin resistance to external aggressions. For dry and sensitive skins

Decrease on TEWL value (5 %, D30), Skin restoring capacity vs Placebo (5 %, 2h, 4h), "Better moisturized, Softer, Better general feeling and oily skin felt matified (5 %, D30; Panelist's evaluation), Silicone-like skin effect

None 2 - 5 %

Liposoluble

SEBOREDUC-TYL

Water (and) Butylene Glycol (and) Hydrolyzed Yeast Protein (and) Fomes Officinalis (Mushroom) Extract (and) Pyridoxine (and) Niacinamide (and) Panthenol (and) Allantoin (and) Threo-nine (and) Biotin

Regulates sebum secre-tion, Decreases the pore size, Improves structure and comfort of oily skin and hair

Inhibition of 5α-reductase activity

Anti-sebum activity and pore size reduction (2 %, D14), "Global improvement of skin condtion", "Less oily skin" (2 %, D14; Panelist's evaluation)

Chlor-phenesin, Pheno-xyethanol

5 - 10 %

Hydrosoluble and soluble in alcohol

TRICHOMEGA

Plukenetia Volubilis Seed Oil Natural oil rich in unsatu-rated poly fatty acids and tocopherols to protect the hair from breakage and split

Reduction of hair breakage (1 %), Reduction of hair split (1 %) (tests on hair tresses)

None 1 - 2 %

Liposoluble

UNCARYL

Propanediol, (and) Water (and) Uncaria Tormentosa Extract

Improves inmunnological system, Anti-oxidant and cyto-protector, Anti-in-flammatory, Anti-aging, Collagen booster

None 3 - 5 %

Hydrosoluble

BOTANICALS

7

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CHINA approved

Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives

Use level Solubility

AMINO GLYCO KVIAR

Water (and) Glycerin (and) Hydrolyzed Roe (and) Glycosami-noglycans (and) Glycogen

Nutrition, Energizing, Regenerating skin and moisturizing, Aged skin

Pheno-xyethanol, Methylpa-raben

1 - 2 %

Hydrosoluble

BIO-MARINE COLLAGEN 6

Soluble Collagen Nutrition of epidermis, Improves skin elasticity, Moisturizer and protector, Provides marine peptides and amino-acids"

Moisturizing effect on human horny layers

Chlor-phenesin, Methylpa-raben

0.5 - 5 %

Hydrosoluble

BIO-MARINE COLLAGEN 6 PH

Soluble Collagen Nutrition of epidermis, Improves skin elasticity, Moisturizer and protector, Provides marine peptides and amino-acids

Moisturizing effect on human horny layers

Phenoxye-thanol

0.5 - 5 %

Hydrosoluble

BIO-MARINE COLLAGEN HAIR

Soluble Collagen Filmogenic on hair damaged scales, Provides moisturization, protection & flexibility, Repairs damaged hairs

Repairing activity on damaged hair

Phenoxye-thanol

3 - 5 %

Hydrosoluble

BIO-MARINE ELASTIN

Hydrolyzed elastin Improves skin elasticity, Protector agent for skin and hair, Increases skin suppleness, Nutrition & regeneration

Pheno-xyethanol, Sorbic acid

5 %

Hydrosoluble

GLYCOENER-GIZER

Water (and) Glycerin (and) Glycogen

Energy source for skin cells, Promotes cell restora-tion and defense, stressed, dulled and tired skins

Growth stimulation on human fibro-blasts compared with epidermal growth factor

Pheno-xyethanol, Methylpa-raben

2 - 5 %

Hydrosoluble

HAIRDENSYL

Water (and) Soluble Collagen (and) Glycerin (and) Propylene Glycol (and) Honey (Mel) extract (and) Sodium PCA (and) Hydrolyzed elastin (and) Serine (and) Glycogen

Treatment to increase hair volume, Nutrition of hair follicles, Improves structure, Hair strengthner, Treatment for hair anti-aging, Helps to reduce hair loss

Protection to damaged hair

Phenozy-ethanol, Sorbic acid

5 - 10 %

Hydrosoluble

HYDRATENSYL COMPLEX

Water (and) Honey extract (and) Soluble Collagen (and) Hydrolyzed elastin (and) Sodium PCA (and) Serine (and) Glycogen

Special complex for skin nutrition, Moisturization and protection from marine & botanical origin

Pheno-xyethanol, Sorbic acid

3 - 5 %

Hydrosoluble

HYDRO MARI-NE COLLAGEN V10

Hydrolyzed Collagen Nutrition of epidermis, Improves elasticity, Moi-sturizing and protecting proteins

Pheno-xyethanol, Chlorphe-nesin

2 - 10 %

Hydrosoluble & soluble in glycols

OCEOVITAL GAG PF

Glycerin (and) Aqua (and) Glyco-saminoglycans (and) Glycogen

Stimulates oxygen consumption, Smoother and filmogenic, Restores energetic reserves, Anti-aging, Anti-stress, Moisturizing

Sodium Benzoate, Potassium sorbate

2 - 5 %

Hydrosoluble

MARINE

8

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We live in a sea of invisible electronic pollution, and the level of electromagnetic radiation (EMR) has dramatically increased over the past decade. Awareness of its detrimental effects is also increasing.

Various studies show that the radiation from mobile telephones has a negative impact on skin. The constant radiation of mobi-le telephones induces hugely elevated production of free radicals (ROS), thus favouring inflammatory responses. These inflammatory responses invoke a massive increase in ATP, which leads to cellular degradation and mitochondrial damage.

The active ingredient Poly-Helixan PF is obtained from the secretion of the garden snail Helix aspersa. This species of snail has existed for 600 million years and has adapted to extreme climatic conditions.

When the snail goes into hibernation, a special secretion polymeri-zes and covers the entrance to its shell to protect the snail’s Body.

Snail farmers in Chile whose hands were frequently exposed to snail secretion discovered that their hands were smoother and that minor wounds would heal faster. This led to the development of the first cream containing snail secretion.

The active ingredient Poly-Helixan PF is a rich complex for skin rege-neration. It is rich in calcium carbonate.

With Cobiodefender EMR, our partner Cobiosa has developed the first active ingredient that protects the skin against the damages of electromagnetic radiation and neutralizes the negative impact of electronic pollution (e-smog).

Cobiodefender EMR reduces the oxidative stress induced by EMR in keratinocytes and reduces excessive accumulation of ATPs (in-vitro). Further tests are being conducted to substantiate these results.

COBIODEFENDER EMR – Protecting the skin against electromagnetic radiation

POLY-HELIXAN PF – Rich, skin-regenerating snail-secretion complex

Composition of Poly-Helixan PF:• Allantoin: Stimulates skin regeneration and possesses regenerative

and anti-inflammatory effects

• Proteins: Nourishing, smoothing and skin texture-improving properties

• Vitamins A, C and E: Stimulates collagen synthesis and skin Regeneration

• Mucopolysaccharides: Moisturizing effect, protects the skin against external stress

• Proteolytic enzymes: Supports the protease/anti-protease

• Balance

• Collagen and elastin: Components of connective tissue

Poly-Helixan PF was tested on 15 volunteers aged between 13 and 55 with scars. The volunteers applied a cosmetic formulation contai-ning 5% Poly-Helixan PF twice daily in the scar area. The measure-ments of skin elasticity (Cutometer) and skin moisture content (Cor-neometer) were taken before and then 30 days after application. The scars were also assessed by video microscopy on Day 0 and on Day 30.

The Cutometer and Corneometer measurements revealed a 32% in-crease in skin elasticity and a 17% increase in skin moisture content. Furthermore, a visible improvement of the scars was observed after 30 days of treatment with 5% Poly-Helixan PF. (Illustration upon re-quest).

Poly-Helixan PF is suitable for applications in the areas of anti-aging, after-sun, aftershave, post-depilation skin care, impure skin and moi-sturizing care.

MARINE

SPECIALTIES

9

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CHINA approved

Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives

Use level Solubility

BIO-CAPIGEN PT

Placental Protein (and) Hydrolyzed Soy Protein (and) Propylene Glycol (and) Panthenol (and) Zinc PCA (and) Glucose (and) Ornithine HCL (and) Niacinamide (and) Arginine HCL (and) Pyridoxine (and) Glucosamine HCL (and) Citruline (and) Biotin

Anti-hair loss active, Improves the hair quality, Strong nutrient for hair health

Improvement of hair density and thickness (2 % Shampoo, 10 % intensive care ampoule, D56), "Hair has more volume and is stronger. The hair loss is reduced during day and while washing" (2 % Sham-poo, 10 % intensive care ampoule, D56; Panelist's evaluation)

Chlorphene-sin, Pheno-xyethanol, Sorbic acid

3 - 10 %

Hydrosoluble

BIO-COLLA-GEN V50

Hydrolized collagen Nutrition of epidermis, Improves elasticity, Moi-sturizing and protecting proteins, Firming

Chlorphene-sin, Sodium deydroace-tate

0.5 - 5 %

Hydrosoluble & soluble in glycols

BIO-HYDRAC-TYL

Water (and) Honey Extract (and) Sodium PCA (and) Serine (and) Glycogen

Hydro-regulator with analogous composition as skin's NMF, Improves water holding capacity of skin, Moisturizer

Skin hydration (ex-vivo) Skin hydration (5 %, 1h)

Phenoxye-thanol

3 - 10 %

Hydrosoluble

BIO-KERATIN PF

Water (and) Hydrolyzed Keratin

Restores cohesion of cuticulary scales, Improves hair's resistance, Hair conditioner, Nutritive for skin, hair and nails

Hair repair Sodium benzoate

5 - 10 %

Hydrosoluble

BIO-NUTRYL Amniotic Fluid Provides hydration and nutrition to the skin and hair, Natural detergent

Methyl-paraben , Hexametilen-trietamine, Sorbic acid

5 - 10 %

Hydrosoluble & soluble in alcohol (max.30º)

BIO-PROTEIN-OL PF

Placental Protein Stimulates oxygen con-sumption and metabolic processes, Strong nutrient, Anti-hair loss, Skin lightener

Stimulation of the oxygen consump-tion of epithelial cells

Chlorphe-nesin

5 - 10 %

Hydrosoluble & soluble in alcohol (max.30º)

BIOSPONGE HYDRACTYL

Honey Extract (and) Sodium PCA (and) Serine (and) Glycogen (and) Nylon 12 (and) Water

Micro-sponges acting as micro vectors for active, Chrono-cosmetics, Long moisturizing treatment, Improves water holding capacity of skin

Phenoxye-thanol

3 - 10 %

Insoluble in oils and water

SPECIALTIES

10

Page 11: Cobiosa - impag.ch...COBIOGUM is compatible with a multitude of cosmetic raw materi-als, can be worked in hot or cold, and is stable over a wide pH range. COBIOGUM leaves behind a

CHINA approved

Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives

Use level Solubility

COBIODEFEN-DER EMR

Aqua (and) Glycerin (and) Glycogen

Electromagnetic Defense Prevention of EMR induced ROS and ATP accumulation, Induction of expression of HSP70 (cytoprotective protein), Reduction of apoptosis in skin cells (ex-vivo), Prevention of desquamation of the stratum cor-neum (ex-vivo), Promotes synthesis of P53 by inducing miR-29b-3p in keratinocytes, Upregulation of fi-bronectin, Reduction of H3K79me3, H3K27me3, H3K9me3 histones

Phenoxye-thanol

2 - 6 %

Hydrosoluble

COBIODEFEN-DER EMR CHL

Aqua (and) Glycerin (and) Glycogen

Electromagnetic Defense Prevention of EMR induced ROS and ATP accumulation, Induction of expression of HSP70 (cytoprotective protein), Reduction of apoptosis in skin cells (ex-vivo), Prevention of desquamation of the stratum cor-neum (ex-vivo), Promotes synthesis of P53 by inducing miR-29b-3p in keratinocytes, Upregulation of fi-bronectin, Reduction of H3K79me3, H3K27me3, H3K9me3 histones

Chlorphe-nesin

2 - 6 %

Hydrosoluble

COBIOREPAIR WGC

Aqua (and) Umbilical Extract Synergistic mixture of con-centrated highly bioactive sulphated glycosamino-glycans (GAGs) of low molecular weight + HA of high and low molecular weight

Anti-oxidant protection on fibroblasts and keratinocytes, Cell chemo-attractive properties, Restoration of cellular matrix, Preservation of cell viability and morphology

Increase of epi-dermal thickness, Keratinocyte number, Collagen III fibers and elastic fibers (0.2 %, D90)

Phenoxye-thanol

0.2 - 3 %

Hydrosoluble

COBIOSTAB 400

Propylene Glycol (and) Hexamidine Diisethionate (and) Water

Hydro-soluble preservative system, Anti-dandruff and aseptizer

Anti-dandruff and anti-desquamation (1.25 %, D7, D14, D28)

Propylene glycol, Hexamidine Diisethionate

0.5 - 1.25 %

Hydrosoluble & soluble in ethanol

HAIR DANDRUFF REDUCER

Propylene Glycol (and) Hexamidine Diisethionate (and) Water

Antiseptic agent for skin and hair, Antimicrobial action against Pityrospo-rum ovale

Anti-dandruff and anti-desquamation (1.25 %, D7, D14, D28)

Propylene glycol, Hexamidine Diisethionate

0.5 - 1.25 %

Hydrosoluble (40-70 ºC) & in ethanol

HENTOWHITE AF

Polysorbate 20 (and) Hexyl-resorcinol (and) Caprylic Acid (and) Isopropyl Alcohol (and) Peg-400 (and) Caproic Acid (and) Capric Acid

Whitening care, Age Spot treatment, Photo-aging. Lightening

Inhibition of tyrosinase activity, Inhibition of melanin synthesis (ex-vivo)

Whitening (0.5 %, D28), "Spots are lighter, skin tone more uniform, skin looks healthier, spots are less percepti-ble" (0.5 %, D28; panelist's evaluation)

None 1 - 3 %

Hydrosoluble

KERATOPEEL Sucrose (and) Silica (and) Keratinase

Enzymatic peeling, Promotes the skin cell regeneration and renewal, Improves the acne and keratosis pilaris

Renewing effect (1 %, D15), Exfoliating effect (1 % D21)

None 2 %

Hydrosoluble

SPECIALTIES

11

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2019 | 06

Product INCI Features in-vitro & ex-vivo in-vivo Preser- vatives

Use level Solubility

LIPOSOMES KERATIN PF

Water (and) Glycerin (and) Sorbitol (and) Hydrolyzed Keratin (and) Lecithin (and) Caprylyl glycol (and) Xanthan gum

Liposomes loaded with Hydrolyzed Keratin at 20 %

Delipidated hair treated with keratin Sodium benzoate

1 - 5 %

Hydrosoluble

NEO-HELIXAN

Water (and) Snail Secretion Filtrate (and) Propylene Glycol (and) Glycerine (and) Glyco-saminoglycans (and) Allantoin (and) Hydrolyzed Collagen (and) Pyridoxine HCL

Skin repair and regenera-tor, Anti-aging complex, Increases skin elasticity and protection

Visible improvement of scars and skin elasticity (5 %, D30)

Pheno-xyethanol, Imidazolidi-nyl urea, Me-thylparaben, Ethylparaben, Propylpara-ben, Butylpa-raben

1 - 5 %

Hydrosoluble, Soluble with tensio-actives and alcohol mixtures

NEO-HELIXAN PF

Water (and) Snail Secretion Filtrate (and) Propylene Glycol (and) Glycerine (and) Glyco-saminoglycans (and) Allantoin (and) Hydrolyzed Collagen (and) Pyridoxine HCL

Skin repair and regenera-tor, Anti-aging complex, Increases skin elasticity and protection

Visible improvement of scars and skin elasticity (5 %, D30)

Phenoxye-thanol

1 - 5 %

Hydrosoluble, Soluble with tensio-actives and alcohol mixtures

POLY-HELIXAN PF

Snail secretion filtrate Skin repairs and rege-nerator, Stretch marks, Increases skin elasticity and protection, Improves skin healing

Visible improvement of scars and skin elasticity (5 %, D30)

Phenoxye-thanol

2 - 5 %

Hydrosoluble

Based on 45 years of experience, Cobiosa develops and manufactures efficient active ingredients for skin care and hair care applications.

The independent company Cobiosa is specialized in the extraction, isolation and purification of various proteins, amino acids, polypep-tides, glycolipids, enzymes and other complexes, and has many years of experience in the manufacture of cosmetic products for third par-ties.

This makes Cobiosa a renowned actives manufacturer with exten-sive know-how in development, production and marketing.

Cobiosa offers support in the registration of cosmetic products, con-ducts stability tests, guarantees the high quality of its raw materials and offers an exciting product portfolio of versatile cosmetic active ingredients.

CHINA approved

Distributed byIMPAG AGRäffelstrasse 128045 ZurichSwitzerland

Phone: +41 43 499 25 00 Fax: +41 43 499 25 01E-Mail: [email protected]: www.impag.ch

IMPAG Group Country OfficesSwitzerland / Zurich – www.impag.chGermany / Offenbach – www.impag.deFrance / Nancy – www.impag.frPoland / Warsaw – www.impag.plAustria / Vienna – www.impag.at

IMPAG Group Head OfficeSwitzerland / Zurich

SPECIALTIES

Natural, effective cosmetic actives

COBIOSA